5FI1 | Genus

Total Genus 123

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	123
sequence length	362
structure length	344
Chain Sequence	GEFAAARESERQLRLRLCVLNEILGTERDYVGTLRFLQSAFLHRIRQNVADSVEKGLTEENVKVLFSNIEDILEVHKDFLAALEYCLHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLVELNKIPTVRAFLLSCMLLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELAKRTPGKHPDHPAVQSALQAMKTVCSNINETKRQMEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRES

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 344 atoms

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344 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Signaling protein
source organism	Homo sapiens
publication title	Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3. pubmed doi rcsb
molecule keywords	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac excha
total genus	123
structure length	344
sequence length	362
ec nomenclature
pdb deposition date	2015-12-22

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00621	RhoGEF	RhoGEF domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.900.10	Mainly Alpha	Up-down Bundle	Dbl Homology Domain; Chain A	Dbl homology (DH) domain	5fi1A01
2.30.29.30	Mainly Beta	Roll	PH-domain like	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	5fi1A02

2M38A 1P5TA 2ZPYA 1H4RA 1MK9B 2VSZA 4MT7A 3PVLA 1OQNA 1WGQA 4GZUA 4HAUB 2UZRA 2YT1A 3CIKA 1W1HA 3AU5A 1XCGA 5D3VA 2D2QA 2GJYA 1XX0A 2D9YA 2JP2A 3FM8C 1V61A 5JLJB 1MIZB 2OQBA 5LOPB 1NI2A 1K5DB 1OMWA 4KVGB 1FHXA 2G35A 1OY2A 2UVMA 4D0OA 2DYQA 2LOZA 1LW3A 3AJ4A 1AWEA 1ZC3B 2ADZA 4L6EA 2X18A 3P7ZA 5HE3A 2J0MA 2W2WA 3RCPA 5D3YA 5DHAB 1EF1A 3HQCA 1UNQA 2CRFA 2MWNB 1NTYA 2AL6A 4CHJA 2CY5A 4KHAA 2ROVA 2DLWA 5DI9B 1WG7A 3P6AA 2YS3A 1PMSA 4ZRIA 2DA0A 1J19A 1EVHA 3QIJA 1I7AA 2AEHA 2QKLA 2HE7A 1DROA 5HE2A 2Z0OA 3IVFA 4K17A 1KZ7A 3A8QA 2Y7BA 3ULCA 3U8ZA 2P0FA 4WVFB 4GOUA 4HDOA 1ZSQA 2RGNB 5J3QA 2DYNA 1DBHA 5C5BB 3V5WA 2P8VA 1UPQA 2YF0A 2IYBA 2K2JA 4ZRJA 1SGHA 1ZVRA 2COFA 1TQZA 2RSGA 3G9WA 2DTCA 3ODOA 3PVUA 2HTHB 2D9WA 1U2BA 3ZDTA 4IOYX 2L1CA 1B55A 4HAZB 3D8DA 1IRSA 1DYNA 4GPTB 2Q13A 5J3TA 1XODA 5CLLB 2QKMA 1NTVA 4HAVB 4DXAB 1BTKA 1WGUA 4Z2NA 4MY6A 2H7DA 2GCLA 4HAXB 4HB0B 1KI1B 1BAKA 2ELBA 1Y5OA 3ML4A 1XD4A 4HHVA 3SO6A 3MPXA 4HAYB 3QWMA 3KRXA 5C6RA 3SV1A 3O96A 5DHFB 2DN6A 1GG3A 2CY4A 4DBBA 4HB2B 1U27A 2ELAA 2LKOA 2I1KA 3F0WA 4IAPA 1J0WA 4K2OA 1TJ6A 2LG1A 4B6HA 2E2XA 4EKUA 3QBVB 2DKPA 2BCJA 1Y19B 5JHHA 1I2HA 2RLOA 4ZRKA 2N0YA 1X05A 2D9ZA 3HK0A 3WYFB 4K81A 1AQCA 1BY1A 1ISNA 3MDBC 2YVCA 2RUKB 2YS5A 5CLQB 5D27A 2D11A 1MPHA 1W1GA 1WJ1A 5HE1A 2RVBB 2I1JA 1N3HA 3ODWA 2EMSA 3PVWA 5C5BA 2IFSA 1MIXA 1LB1A 4HDQA 3D8EA 1ZC4B 2KCJA 2MFQA 4TYZA 1F5XA 2KR9A 3TVVA 1FOEA 2Y8GA 4F7UP 1Q67A 2D4QA 4F7GA 4DX90 2CODA 3BJIA 2Z0PA 5KQ1A 1U5DA 2XQNM 5C16A 2DKQA 2I5FA 3DXEA 3NSUA 4DX8A 1DDWA 1ZM0A 5D3WA 2VRWB 3DXCA 1BWNA 2DFKA 3M1IB 5J3YA 3N7CA 1Z87A 2J0JA 1U5FA 2KUPA 4Y94A 4PNKA 5JP4A 1U5GA 2YT0A 5DIFB 1BTNA 3U7DA 4BBKA 1WVHA 1X1GA 1V5MA 3ODXA 2K00A 3VIAA 1EGXA 1UNPA 1V88A 3A8PA 1W1DA 1V89A 1FB8A 2DHKA 1H10A 1X11A 4CHMA 5LONB 2J59M 4K2PA 1V5PA 1PFJA 2Z0QA 5KQ4A 3LJUX 4GN1A 3KY9A 3AU4A 2DX1A 2K2UA 1FHWA 3TW1A 2D10A 1UPRA 4GXBA 3KSYA 5L81A 3D8FA 4GMVA 3FEHA 1DDVA 2COCA 3CXBB 4A6HA 4YL8A 4C0AA 2GCJA 4HB4B 1XR0B 5GOWB 4NSWA 3ZVRA 1XKEA 5C79A 2OTXA 3GYOA 4P7IA 1NU2A 1UNRA 2CAYA 1MK7B 3PP2A 5JHGA 1FHOA 5FI1A 3T06A 1P3RA 1PLSA 1V5UA 2J0KA 2MDXA 3F5RA 4Z2MB 2V76A 3ULBA 2LULA 2DHJA 2DX5A 3PEGA 2P0HA 2KGXB 5D3XA 1QQGA 2M14A 4HB3B 3SNHA 3TCAA 3GYPA 1QC6A 1SHCA 3HW2B 2W2XD 1EAZA 1K5GB 3PG7A 4IFSA 2R09A 3KRWA 4A6FA 4WSFA 1RJ2A 3DXDA 3EO2A 2H7EA 4NY0A 3BINA 4HATB 3TO1A 2EJ8A 5DH9B 1M7RA 2EC1A 4GYVA 5HE0A 2UZSA 2Y8FA 3OANA 1X86A 1MKEA 2RNRB 3X23A 2NZ8B 1FGZA 5KCVA 2LOXA 2VKIA 2I5CA 4CYEA 3WA0A 4KHOA 4XWXA 4TKNA 3JV3A 4A6FB 1WJMA 2N23A 1DDMA 5FI0A 2D9XA 3A98B 4EJNA 3SYXA 2YSZA 2EMTA 1MAIA 3TFMA 2YRYA 5EFXA 4PQ0A 2FJLA 1GC6A 4D0NB 4EMOA 1WI1A 2R0DA 2YS1A 2W2XC 4F7HA 3PSCA 2P0DA 4A6KA 3KZ1A 1UEFA 2L2IA 1X1FA 2NMBA 2GS0A 1RRPB 2D9VA 1U29A 4H8SA 1P6SA 2PZ1A 4YONA 3GF9A 4KAXB 3FSSA 2MKRA 4KHBB 4MK0A 1U5EA 1FAOA 2ROZB 3UZTA 4GMXB 4A5KA 4HAWB 3PZDA 3VOQA 1M7EA 2DHIA 2COAA 4WJ7A 1TXDA 3SUZA 1KZGA 1E5WA 1FGYA 2LYDA 1GC7A
chains in the Genus database with same CATH superfamily

2M38A 1P5TA 2ZPYA 1H4RA 1MK9B 2VSZA 4MT7A 3PVLA 1OQNA 1WGQA 4GZUA 4HAUB 2UZRA 2YT1A 3CIKA 1W1HA 3AU5A 1XCGA 5D3VA 2GUMA 2D2QA 2GJYA 1XX0A 2D9YA 2JP2A 3FM8C 1V61A 5JLJB 1MIZB 3HIEA 2OQBA 5I2SA 5LOPB 1NI2A 1K5DB 1OMWA 4KVGB 1FHXA 2G35A 1OY2A 2UVMA 4D0OA 2DYQA 2LOZA 1LW3A 3AJ4A 1AWEA 1ZC3B 2ADZA 4L6EA 2X18A 3P7ZA 5HE3A 2J0MA 2W2WA 3RCPA 5D3YA 5DHAB 1EF1A 3HQCA 1UNQA 2CRFA 2MWNB 1NTYA 2AL6A 4CHJA 2CY5A 4KHAA 2ROVA 2DLWA 5DI9B 1WG7A 3P6AA 2YS3A 1PMSA 4ZRIA 2DA0A 1J19A 1EVHA 3QIJA 1I7AA 2AEHA 2QKLA 2HE7A 1DROA 1MI1A 5HE2A 2Z0OA 3IVFA 4K17A 3NWFA 1KZ7A 3A8QA 2Y7BA 3ULCA 3U8ZA 2P0FA 4WVFB 4KHBA 4GOUA 4HDOA 1ZSQA 2RGNB 5J3QA 2DYNA 1DBHA 5C5BB 3V5WA 2P8VA 1UPQA 2YF0A 2IYBA 2K2JA 4ZRJA 1SGHA 1ZVRA 2COFA 4QJ4B 1TQZA 2RSGA 3G9WA 2DTCA 3ODOA 3PVUA 2HTHB 2D9WA 1U2BA 3ZDTA 4IOYX 2L1CA 1B55A 4HAZB 3D8DA 1IRSA 1DYNA 4GPTB 2Q13A 5J3TA 1XODA 5CLLB 2QKMA 1NTVA 4HAVB 4DXAB 4QJ5B 5LG4B 1BTKA 1WGUA 4Z2NA 4MY6A 2H7DA 2GCLA 5M4YB 4HAXB 4HB0B 1KI1B 4OSNA 2Z59A 3NW8A 1BAKA 2ELBA 1Y5OA 3ML4A 2NBVA 1XD4A 4HHVA 3SO6A 3MPXA 4HAYB 3QWMA 3KRXA 2KR0A 5C6RA 3SV1A 2Z4DA 3O96A 5DHFB 2DN6A 2Z14A 1GG3A 2CY4A 4DBBA 4HB2B 1U27A 2ELAA 1ZYIA 2LKOA 5IRSA 2I1KA 3F0WA 4IAPA 1J0WA 4K2OA 1TJ6A 2LG1A 4B6HA 2E2XA 4EKUA 3QBVB 2DKPA 2BCJA 1Y19B 5JHHA 1I2HA 2RLOA 4ZRKA 2R2YA 3NWDA 2N0YA 2KIGA 1X05A 2D9ZA 3HK0A 3WYFB 4K81A 1AQCA 1BY1A 1ISNA 3HSAA 4L1RA 3MDBC 2YVCA 2RUKB 2YS5A 5CLQB 4CSQA 5D27A 2D11A 1MPHA 1W1GA 1WJ1A 5HE1A 2RVBB 2I1JA 1N3HA 3ODWA 2EMSA 3PVWA 5C5BA 2IFSA 1MIXA 1LB1A 4HDQA 2FJUB 3D8EA 1ZC4B 2KCJA 2MFQA 4TYZA 1F5XA 2KR9A 3TVVA 1FOEA 2Y8GA 4F7UP 1Q67A 2D4QA 4F7GA 4DX90 2CODA 3BJIA 2Z0PA 5KQ1A 1U5DA 2XQNM 5C16A 2DKQA 2I5FA 3DXEA 3NSUA 4DX8A 1DDWA 1ZM0A 5D3WA 2VRWB 3A58A 3DXCA 1BWNA 2DFKA 3M1IB 5J3YA 3N7CA 1Z87A 2J0JA 1U5FA 2KUPA 2ZKMX 4Y94A 4PNKA 5JP4A 1U5GA 2YT0A 5DIFB 1BTNA 3U7DA 4BBKA 1WVHA 1X1GA 1V5MA 3ODXA 2K00A 3VIAA 1EGXA 1UNPA 1V88A 3A8PA 1W1DA 3OHMB 3NWAA 4HSIA 1V89A 2YT2A 1FB8A 2DHKA 1H10A 1X11A 4CHMA 5LONB 2J59M 2KUQA 4K2PA 1V5PA 1PFJA 2Z0QA 5KQ4A 4DIXA 3LJUX 4GN1A 3KY9A 3AU4A 2DX1A 2K2UA 1FHWA 3TW1A 2D10A 1UPRA 5I2MA 4GXBA 3KSYA 5L81A 3D8FA 4GMVA 3B77A 3FEHA 1DDVA 2COCA 3CXBB 4A6HA 4YL8A 4C0AA 2GCJA 4HB4B 1XR0B 5GOWB 4NSWA 3ZVRA 1XKEA 5C79A 2OTXA 3GYOA 4P7IA 1NU2A 4D6WA 1UNRA 2CAYA 1MK7B 3PP2A 5JHGA 1FHOA 3FVCA 5FI1A 3T06A 1P3RA 1PLSA 1V5UA 2J0KA 2MDXA 3F5RA 4Z2MB 2V76A 3ULBA 2LULA 2DHJA 2DX5A 2RRFA 3PEGA 4GNKB 2P0HA 2KGXB 5D3XA 1QQGA 2M14A 4HB3B 3SNHA 3TCAA 3GYPA 1QC6A 1SHCA 3HW2B 2W2XD 1EAZA 1K5GB 3PG7A 4IFSA 3DCXA 2R09A 3KRWA 4A6FA 4WSFA 1RJ2A 3DXDA 3EO2A 2H7EA 4NY0A 3BINA 4HATB 4QJ3B 3TO1A 2EJ8A 5DH9B 1M7RA 4OT1A 2EC1A 4GYVA 5HE0A 2UZSA 2Y8FA 3OANA 1X86A 1MKEA 2RNRB 3X23A 2NZ8B 1FGZA 5KCVA 2LOXA 2VKIA 2I5CA 4CYEA 3WA0A 4KHOA 4XWXA 4TKNA 3JV3A 4A6FB 2KIEA 1WJMA 2N23A 1DDMA 1T77A 5FI0A 2D9XA 3A98B 4EJNA 3SYXA 2YSZA 2EMTA 1MAIA 3TFMA 2YRYA 5EFXA 4PQ0A 2FJLA 1GC6A 4D0NB 4EMOA 1WI1A 2R0DA 2YS1A 2W2XC 4F7HA 3PSCA 2P0DA 4A6KA 2K49A 3KZ1A 1UEFA 2L2IA 1X1FA 2NMBA 2GS0A 1RRPB 2D9VA 1U29A 4H8SA 1P6SA 2PZ1A 4YONA 3GF9A 4KAXB 3FSSA 2MKRA 4KHBB 4MK0A 1U5EA 1FAOA 2ROZB 3UZTA 4GMXB 4A5KA 2Z13A 4HAWB 2K8EA 3PZDA 3VOQA 1M7EA 2DHIA 2COAA 4WJ7A 3U12A 1TXDA 4QXAB 3SUZA 1KZGA 1E5WA 1FGYA 2LYDA 1GC7A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2M38 A;  1P5T A;  2ZPY A;  1H4R A;  1MK9 B;  2VSZ A;  4MT7 A;  3PVL A;  1OQN A;  1WGQ A;  4GZU A;  4HAU B;  2UZR A;  2YT1 A;  3CIK A;  1W1H A;  3AU5 A;  1XCG A;  5D3V A;  2D2Q A;  2GJY A;  1XX0 A;  2D9Y A;  2JP2 A;  3FM8 C;  1V61 A;  5JLJ B;  1MIZ B;  2OQB A;  5LOP B;  1NI2 A;  1K5D B;  1OMW A;  4KVG B;  1FHX A;  2G35 A;  1OY2 A;  2UVM A;  4D0O A;  2DYQ A;  2LOZ A;  1LW3 A;  3AJ4 A;  1AWE A;  1ZC3 B;  2ADZ A;  4L6E A;  2X18 A;  3P7Z A;  5HE3 A;  2J0M A;  2W2W A;  3RCP A;  5D3Y A;  5DHA B;  1EF1 A;  3HQC A;  1UNQ A;  2CRF A;  2MWN B;  1NTY A;  2AL6 A;  4CHJ A;  2CY5 A;  4KHA A;  2ROV A;  2DLW A;  5DI9 B;  1WG7 A;  3P6A A;  2YS3 A;  1PMS A;  4ZRI A;  2DA0 A;  1J19 A;  1EVH A;  3QIJ A;  1I7A A;  2AEH A;  2QKL A;  2HE7 A;  1DRO A;  5HE2 A;  2Z0O A;  3IVF A;  4K17 A;  1KZ7 A;  3A8Q A;  2Y7B A;  3ULC A;  3U8Z A;  2P0F A;  4WVF B;  4GOU A;  4HDO A;  1ZSQ A;  2RGN B;  5J3Q A;  2DYN A;  1DBH A;  5C5B B;  3V5W A;  2P8V A;  1UPQ A;  2YF0 A;  2IYB A;  2K2J A;  4ZRJ A;  1SGH A;  1ZVR A;  2COF A;  1TQZ A;  2RSG A;  3G9W A;  2DTC A;  3ODO A;  3PVU A;  2HTH B;  2D9W A;  1U2B A;  3ZDT A;  4IOY X;  2L1C A;  1B55 A;  4HAZ B;  3D8D A;  1IRS A;  1DYN A;  4GPT B;  2Q13 A;  5J3T A;  1XOD A;  5CLL B;  2QKM A;  1NTV A;  4HAV B;  4DXA B;  1BTK A;  1WGU A;  4Z2N A;  4MY6 A;  2H7D A;  2GCL A;  4HAX B;  4HB0 B;  1KI1 B;  1BAK A;  2ELB A;  1Y5O A;  3ML4 A;  1XD4 A;  4HHV A;  3SO6 A;  3MPX A;  4HAY B;  3QWM A;  3KRX A;  5C6R A;  3SV1 A;  3O96 A;  5DHF B;  2DN6 A;  1GG3 A;  2CY4 A;  4DBB A;  4HB2 B;  1U27 A;  2ELA A;  2LKO A;  2I1K A;  3F0W A;  4IAP A;  1J0W A;  4K2O A;  1TJ6 A;  2LG1 A;  4B6H A;  2E2X A;  4EKU A;  3QBV B;  2DKP A;  2BCJ A;  1Y19 B;  5JHH A;  1I2H A;  2RLO A;  4ZRK A;  2N0Y A;  1X05 A;  2D9Z A;  3HK0 A;  3WYF B;  4K81 A;  1AQC A;  1BY1 A;  1ISN A;  3MDB C;  2YVC A;  2RUK B;  2YS5 A;  5CLQ B;  5D27 A;  2D11 A;  1MPH A;  1W1G A;  1WJ1 A;  5HE1 A;  2RVB B;  2I1J A;  1N3H A;  3ODW A;  2EMS A;  3PVW A;  5C5B A;  2IFS A;  1MIX A;  1LB1 A;  4HDQ A;  3D8E A;  1ZC4 B;  2KCJ A;  2MFQ A;  4TYZ A;  1F5X A;  2KR9 A;  3TVV A;  1FOE A;  2Y8G A;  4F7U P;  1Q67 A;  2D4Q A;  4F7G A;  4DX9 0;  2COD A;  3BJI A;  2Z0P A;  5KQ1 A;  1U5D A;  2XQN M;  5C16 A;  2DKQ A;  2I5F A;  3DXE A;  3NSU A;  4DX8 A;  1DDW A;  1ZM0 A;  5D3W A;  2VRW B;  3DXC A;  1BWN A;  2DFK A;  3M1I B;  5J3Y A;  3N7C A;  1Z87 A;  2J0J A;  1U5F A;  2KUP A;  4Y94 A;  4PNK A;  5JP4 A;  1U5G A;  2YT0 A;  5DIF B;  1BTN A;  3U7D A;  4BBK A;  1WVH A;  1X1G A;  1V5M A;  3ODX A;  2K00 A;  3VIA A;  1EGX A;  1UNP A;  1V88 A;  3A8P A;  1W1D A;  1V89 A;  1FB8 A;  2DHK A;  1H10 A;  1X11 A;  4CHM A;  5LON B;  2J59 M;  4K2P A;  1V5P A;  1PFJ A;  2Z0Q A;  5KQ4 A;  3LJU X;  4GN1 A;  3KY9 A;  3AU4 A;  2DX1 A;  2K2U A;  1FHW A;  3TW1 A;  2D10 A;  1UPR A;  4GXB A;  3KSY A;  5L81 A;  3D8F A;  4GMV A;  3FEH A;  1DDV A;  2COC A;  3CXB B;  4A6H A;  4YL8 A;  4C0A A;  2GCJ A;  4HB4 B;  1XR0 B;  5GOW B;  4NSW A;  3ZVR A;  1XKE A;  5C79 A;  2OTX A;  3GYO A;  4P7I A;  1NU2 A;  1UNR A;  2CAY A;  1MK7 B;  3PP2 A;  5JHG A;  1FHO A;  5FI1 A;  3T06 A;  1P3R A;  1PLS A;  1V5U A;  2J0K A;  2MDX A;  3F5R A;  4Z2M B;  2V76 A;  3ULB A;  2LUL A;  2DHJ A;  2DX5 A;  3PEG A;  2P0H A;  2KGX B;  5D3X A;  1QQG A;  2M14 A;  4HB3 B;  3SNH A;  3TCA A;  3GYP A;  1QC6 A;  1SHC A;  3HW2 B;  2W2X D;  1EAZ A;  1K5G B;  3PG7 A;  4IFS A;  2R09 A;  3KRW A;  4A6F A;  4WSF A;  1RJ2 A;  3DXD A;  3EO2 A;  2H7E A;  4NY0 A;  3BIN A;  4HAT B;  3TO1 A;  2EJ8 A;  5DH9 B;  1M7R A;  2EC1 A;  4GYV A;  5HE0 A;  2UZS A;  2Y8F A;  3OAN A;  1X86 A;  1MKE A;  2RNR B;  3X23 A;  2NZ8 B;  1FGZ A;  5KCV A;  2LOX A;  2VKI A;  2I5C A;  4CYE A;  3WA0 A;  4KHO A;  4XWX A;  4TKN A;  3JV3 A;  4A6F B;  1WJM A;  2N23 A;  1DDM A;  5FI0 A;  2D9X A;  3A98 B;  4EJN A;  3SYX A;  2YSZ A;  2EMT A;  1MAI A;  3TFM A;  2YRY A;  5EFX A;  4PQ0 A;  2FJL A;  1GC6 A;  4D0N B;  4EMO A;  1WI1 A;  2R0D A;  2YS1 A;  2W2X C;  4F7H A;  3PSC A;  2P0D A;  4A6K A;  3KZ1 A;  1UEF A;  2L2I A;  1X1F A;  2NMB A;  2GS0 A;  1RRP B;  2D9V A;  1U29 A;  4H8S A;  1P6S A;  2PZ1 A;  4YON A;  3GF9 A;  4KAX B;  3FSS A;  2MKR A;  4KHB B;  4MK0 A;  1U5E A;  1FAO A;  2ROZ B;  3UZT A;  4GMX B;  4A5K A;  4HAW B;  3PZD A;  3VOQ A;  1M7E A;  2DHI A;  2COA A;  4WJ7 A;  1TXD A;  3SUZ A;  1KZG A;  1E5W A;  1FGY A;  2LYD A;  1GC7 A; 
#chains in the Genus database with same CATH topology
 2M38 A;  1P5T A;  2ZPY A;  1H4R A;  1MK9 B;  2VSZ A;  4MT7 A;  3PVL A;  1OQN A;  1WGQ A;  4GZU A;  4HAU B;  2UZR A;  2YT1 A;  3CIK A;  1W1H A;  3AU5 A;  1XCG A;  5D3V A;  2GUM A;  2D2Q A;  2GJY A;  1XX0 A;  2D9Y A;  2JP2 A;  3FM8 C;  1V61 A;  5JLJ B;  1MIZ B;  3HIE A;  2OQB A;  5I2S A;  5LOP B;  1NI2 A;  1K5D B;  1OMW A;  4KVG B;  1FHX A;  2G35 A;  1OY2 A;  2UVM A;  4D0O A;  2DYQ A;  2LOZ A;  1LW3 A;  3AJ4 A;  1AWE A;  1ZC3 B;  2ADZ A;  4L6E A;  2X18 A;  3P7Z A;  5HE3 A;  2J0M A;  2W2W A;  3RCP A;  5D3Y A;  5DHA B;  1EF1 A;  3HQC A;  1UNQ A;  2CRF A;  2MWN B;  1NTY A;  2AL6 A;  4CHJ A;  2CY5 A;  4KHA A;  2ROV A;  2DLW A;  5DI9 B;  1WG7 A;  3P6A A;  2YS3 A;  1PMS A;  4ZRI A;  2DA0 A;  1J19 A;  1EVH A;  3QIJ A;  1I7A A;  2AEH A;  2QKL A;  2HE7 A;  1DRO A;  1MI1 A;  5HE2 A;  2Z0O A;  3IVF A;  4K17 A;  3NWF A;  1KZ7 A;  3A8Q A;  2Y7B A;  3ULC A;  3U8Z A;  2P0F A;  4WVF B;  4KHB A;  4GOU A;  4HDO A;  1ZSQ A;  2RGN B;  5J3Q A;  2DYN A;  1DBH A;  5C5B B;  3V5W A;  2P8V A;  1UPQ A;  2YF0 A;  2IYB A;  2K2J A;  4ZRJ A;  1SGH A;  1ZVR A;  2COF A;  4QJ4 B;  1TQZ A;  2RSG A;  3G9W A;  2DTC A;  3ODO A;  3PVU A;  2HTH B;  2D9W A;  1U2B A;  3ZDT A;  4IOY X;  2L1C A;  1B55 A;  4HAZ B;  3D8D A;  1IRS A;  1DYN A;  4GPT B;  2Q13 A;  5J3T A;  1XOD A;  5CLL B;  2QKM A;  1NTV A;  4HAV B;  4DXA B;  4QJ5 B;  5LG4 B;  1BTK A;  1WGU A;  4Z2N A;  4MY6 A;  2H7D A;  2GCL A;  5M4Y B;  4HAX B;  4HB0 B;  1KI1 B;  4OSN A;  2Z59 A;  3NW8 A;  1BAK A;  2ELB A;  1Y5O A;  3ML4 A;  2NBV A;  1XD4 A;  4HHV A;  3SO6 A;  3MPX A;  4HAY B;  3QWM A;  3KRX A;  2KR0 A;  5C6R A;  3SV1 A;  2Z4D A;  3O96 A;  5DHF B;  2DN6 A;  2Z14 A;  1GG3 A;  2CY4 A;  4DBB A;  4HB2 B;  1U27 A;  2ELA A;  1ZYI A;  2LKO A;  5IRS A;  2I1K A;  3F0W A;  4IAP A;  1J0W A;  4K2O A;  1TJ6 A;  2LG1 A;  4B6H A;  2E2X A;  4EKU A;  3QBV B;  2DKP A;  2BCJ A;  1Y19 B;  5JHH A;  1I2H A;  2RLO A;  4ZRK A;  2R2Y A;  3NWD A;  2N0Y A;  2KIG A;  1X05 A;  2D9Z A;  3HK0 A;  3WYF B;  4K81 A;  1AQC A;  1BY1 A;  1ISN A;  3HSA A;  4L1R A;  3MDB C;  2YVC A;  2RUK B;  2YS5 A;  5CLQ B;  4CSQ A;  5D27 A;  2D11 A;  1MPH A;  1W1G A;  1WJ1 A;  5HE1 A;  2RVB B;  2I1J A;  1N3H A;  3ODW A;  2EMS A;  3PVW A;  5C5B A;  2IFS A;  1MIX A;  1LB1 A;  4HDQ A;  2FJU B;  3D8E A;  1ZC4 B;  2KCJ A;  2MFQ A;  4TYZ A;  1F5X A;  2KR9 A;  3TVV A;  1FOE A;  2Y8G A;  4F7U P;  1Q67 A;  2D4Q A;  4F7G A;  4DX9 0;  2COD A;  3BJI A;  2Z0P A;  5KQ1 A;  1U5D A;  2XQN M;  5C16 A;  2DKQ A;  2I5F A;  3DXE A;  3NSU A;  4DX8 A;  1DDW A;  1ZM0 A;  5D3W A;  2VRW B;  3A58 A;  3DXC A;  1BWN A;  2DFK A;  3M1I B;  5J3Y A;  3N7C A;  1Z87 A;  2J0J A;  1U5F A;  2KUP A;  2ZKM X;  4Y94 A;  4PNK A;  5JP4 A;  1U5G A;  2YT0 A;  5DIF B;  1BTN A;  3U7D A;  4BBK A;  1WVH A;  1X1G A;  1V5M A;  3ODX A;  2K00 A;  3VIA A;  1EGX A;  1UNP A;  1V88 A;  3A8P A;  1W1D A;  3OHM B;  3NWA A;  4HSI A;  1V89 A;  2YT2 A;  1FB8 A;  2DHK A;  1H10 A;  1X11 A;  4CHM A;  5LON B;  2J59 M;  2KUQ A;  4K2P A;  1V5P A;  1PFJ A;  2Z0Q A;  5KQ4 A;  4DIX A;  3LJU X;  4GN1 A;  3KY9 A;  3AU4 A;  2DX1 A;  2K2U A;  1FHW A;  3TW1 A;  2D10 A;  1UPR A;  5I2M A;  4GXB A;  3KSY A;  5L81 A;  3D8F A;  4GMV A;  3B77 A;  3FEH A;  1DDV A;  2COC A;  3CXB B;  4A6H A;  4YL8 A;  4C0A A;  2GCJ A;  4HB4 B;  1XR0 B;  5GOW B;  4NSW A;  3ZVR A;  1XKE A;  5C79 A;  2OTX A;  3GYO A;  4P7I A;  1NU2 A;  4D6W A;  1UNR A;  2CAY A;  1MK7 B;  3PP2 A;  5JHG A;  1FHO A;  3FVC A;  5FI1 A;  3T06 A;  1P3R A;  1PLS A;  1V5U A;  2J0K A;  2MDX A;  3F5R A;  4Z2M B;  2V76 A;  3ULB A;  2LUL A;  2DHJ A;  2DX5 A;  2RRF A;  3PEG A;  4GNK B;  2P0H A;  2KGX B;  5D3X A;  1QQG A;  2M14 A;  4HB3 B;  3SNH A;  3TCA A;  3GYP A;  1QC6 A;  1SHC A;  3HW2 B;  2W2X D;  1EAZ A;  1K5G B;  3PG7 A;  4IFS A;  3DCX A;  2R09 A;  3KRW A;  4A6F A;  4WSF A;  1RJ2 A;  3DXD A;  3EO2 A;  2H7E A;  4NY0 A;  3BIN A;  4HAT B;  4QJ3 B;  3TO1 A;  2EJ8 A;  5DH9 B;  1M7R A;  4OT1 A;  2EC1 A;  4GYV A;  5HE0 A;  2UZS A;  2Y8F A;  3OAN A;  1X86 A;  1MKE A;  2RNR B;  3X23 A;  2NZ8 B;  1FGZ A;  5KCV A;  2LOX A;  2VKI A;  2I5C A;  4CYE A;  3WA0 A;  4KHO A;  4XWX A;  4TKN A;  3JV3 A;  4A6F B;  2KIE A;  1WJM A;  2N23 A;  1DDM A;  1T77 A;  5FI0 A;  2D9X A;  3A98 B;  4EJN A;  3SYX A;  2YSZ A;  2EMT A;  1MAI A;  3TFM A;  2YRY A;  5EFX A;  4PQ0 A;  2FJL A;  1GC6 A;  4D0N B;  4EMO A;  1WI1 A;  2R0D A;  2YS1 A;  2W2X C;  4F7H A;  3PSC A;  2P0D A;  4A6K A;  2K49 A;  3KZ1 A;  1UEF A;  2L2I A;  1X1F A;  2NMB A;  2GS0 A;  1RRP B;  2D9V A;  1U29 A;  4H8S A;  1P6S A;  2PZ1 A;  4YON A;  3GF9 A;  4KAX B;  3FSS A;  2MKR A;  4KHB B;  4MK0 A;  1U5E A;  1FAO A;  2ROZ B;  3UZT A;  4GMX B;  4A5K A;  2Z13 A;  4HAW B;  2K8E A;  3PZD A;  3VOQ A;  1M7E A;  2DHI A;  2COA A;  4WJ7 A;  3U12 A;  1TXD A;  4QXA B;  3SUZ A;  1KZG A;  1E5W A;  1FGY A;  2LYD A;  1GC7 A; 
#chains in the Genus database with same CATH homology
 2M38 A;  1P5T A;  2ZPY A;  1H4R A;  1MK9 B;  2VSZ A;  4MT7 A;  3PVL A;  1OQN A;  1WGQ A;  4GZU A;  4HAU B;  2UZR A;  2YT1 A;  3CIK A;  1W1H A;  3AU5 A;  1XCG A;  5D3V A;  2D2Q A;  2GJY A;  1XX0 A;  2D9Y A;  2JP2 A;  3FM8 C;  1V61 A;  5JLJ B;  1MIZ B;  2OQB A;  5LOP B;  1NI2 A;  1K5D B;  1OMW A;  4KVG B;  1FHX A;  2G35 A;  1OY2 A;  2UVM A;  4D0O A;  2DYQ A;  2LOZ A;  1LW3 A;  3AJ4 A;  1AWE A;  1ZC3 B;  2ADZ A;  4L6E A;  2X18 A;  3P7Z A;  5HE3 A;  2J0M A;  2W2W A;  3RCP A;  5D3Y A;  5DHA B;  1EF1 A;  3HQC A;  1UNQ A;  2CRF A;  2MWN B;  1NTY A;  2AL6 A;  4CHJ A;  2CY5 A;  4KHA A;  2ROV A;  2DLW A;  5DI9 B;  1WG7 A;  3P6A A;  2YS3 A;  1PMS A;  4ZRI A;  2DA0 A;  1J19 A;  1EVH A;  3QIJ A;  1I7A A;  2AEH A;  2QKL A;  2HE7 A;  1DRO A;  5HE2 A;  2Z0O A;  3IVF A;  4K17 A;  1KZ7 A;  3A8Q A;  2Y7B A;  3ULC A;  3U8Z A;  2P0F A;  4WVF B;  4GOU A;  4HDO A;  1ZSQ A;  2RGN B;  5J3Q A;  2DYN A;  1DBH A;  5C5B B;  3V5W A;  2P8V A;  1UPQ A;  2YF0 A;  2IYB A;  2K2J A;  4ZRJ A;  1SGH A;  1ZVR A;  2COF A;  1TQZ A;  2RSG A;  3G9W A;  2DTC A;  3ODO A;  3PVU A;  2HTH B;  2D9W A;  1U2B A;  3ZDT A;  4IOY X;  2L1C A;  1B55 A;  4HAZ B;  3D8D A;  1IRS A;  1DYN A;  4GPT B;  2Q13 A;  5J3T A;  1XOD A;  5CLL B;  2QKM A;  1NTV A;  4HAV B;  4DXA B;  1BTK A;  1WGU A;  4Z2N A;  4MY6 A;  2H7D A;  2GCL A;  4HAX B;  4HB0 B;  1KI1 B;  1BAK A;  2ELB A;  1Y5O A;  3ML4 A;  1XD4 A;  4HHV A;  3SO6 A;  3MPX A;  4HAY B;  3QWM A;  3KRX A;  5C6R A;  3SV1 A;  3O96 A;  5DHF B;  2DN6 A;  1GG3 A;  2CY4 A;  4DBB A;  4HB2 B;  1U27 A;  2ELA A;  2LKO A;  2I1K A;  3F0W A;  4IAP A;  1J0W A;  4K2O A;  1TJ6 A;  2LG1 A;  4B6H A;  2E2X A;  4EKU A;  3QBV B;  2DKP A;  2BCJ A;  1Y19 B;  5JHH A;  1I2H A;  2RLO A;  4ZRK A;  2N0Y A;  1X05 A;  2D9Z A;  3HK0 A;  3WYF B;  4K81 A;  1AQC A;  1BY1 A;  1ISN A;  3MDB C;  2YVC A;  2RUK B;  2YS5 A;  5CLQ B;  5D27 A;  2D11 A;  1MPH A;  1W1G A;  1WJ1 A;  5HE1 A;  2RVB B;  2I1J A;  1N3H A;  3ODW A;  2EMS A;  3PVW A;  5C5B A;  2IFS A;  1MIX A;  1LB1 A;  4HDQ A;  3D8E A;  1ZC4 B;  2KCJ A;  2MFQ A;  4TYZ A;  1F5X A;  2KR9 A;  3TVV A;  1FOE A;  2Y8G A;  4F7U P;  1Q67 A;  2D4Q A;  4F7G A;  4DX9 0;  2COD A;  3BJI A;  2Z0P A;  5KQ1 A;  1U5D A;  2XQN M;  5C16 A;  2DKQ A;  2I5F A;  3DXE A;  3NSU A;  4DX8 A;  1DDW A;  1ZM0 A;  5D3W A;  2VRW B;  3DXC A;  1BWN A;  2DFK A;  3M1I B;  5J3Y A;  3N7C A;  1Z87 A;  2J0J A;  1U5F A;  2KUP A;  4Y94 A;  4PNK A;  5JP4 A;  1U5G A;  2YT0 A;  5DIF B;  1BTN A;  3U7D A;  4BBK A;  1WVH A;  1X1G A;  1V5M A;  3ODX A;  2K00 A;  3VIA A;  1EGX A;  1UNP A;  1V88 A;  3A8P A;  1W1D A;  1V89 A;  1FB8 A;  2DHK A;  1H10 A;  1X11 A;  4CHM A;  5LON B;  2J59 M;  4K2P A;  1V5P A;  1PFJ A;  2Z0Q A;  5KQ4 A;  3LJU X;  4GN1 A;  3KY9 A;  3AU4 A;  2DX1 A;  2K2U A;  1FHW A;  3TW1 A;  2D10 A;  1UPR A;  4GXB A;  3KSY A;  5L81 A;  3D8F A;  4GMV A;  3FEH A;  1DDV A;  2COC A;  3CXB B;  4A6H A;  4YL8 A;  4C0A A;  2GCJ A;  4HB4 B;  1XR0 B;  5GOW B;  4NSW A;  3ZVR A;  1XKE A;  5C79 A;  2OTX A;  3GYO A;  4P7I A;  1NU2 A;  1UNR A;  2CAY A;  1MK7 B;  3PP2 A;  5JHG A;  1FHO A;  5FI1 A;  3T06 A;  1P3R A;  1PLS A;  1V5U A;  2J0K A;  2MDX A;  3F5R A;  4Z2M B;  2V76 A;  3ULB A;  2LUL A;  2DHJ A;  2DX5 A;  3PEG A;  2P0H A;  2KGX B;  5D3X A;  1QQG A;  2M14 A;  4HB3 B;  3SNH A;  3TCA A;  3GYP A;  1QC6 A;  1SHC A;  3HW2 B;  2W2X D;  1EAZ A;  1K5G B;  3PG7 A;  4IFS A;  2R09 A;  3KRW A;  4A6F A;  4WSF A;  1RJ2 A;  3DXD A;  3EO2 A;  2H7E A;  4NY0 A;  3BIN A;  4HAT B;  3TO1 A;  2EJ8 A;  5DH9 B;  1M7R A;  2EC1 A;  4GYV A;  5HE0 A;  2UZS A;  2Y8F A;  3OAN A;  1X86 A;  1MKE A;  2RNR B;  3X23 A;  2NZ8 B;  1FGZ A;  5KCV A;  2LOX A;  2VKI A;  2I5C A;  4CYE A;  3WA0 A;  4KHO A;  4XWX A;  4TKN A;  3JV3 A;  4A6F B;  1WJM A;  2N23 A;  1DDM A;  5FI0 A;  2D9X A;  3A98 B;  4EJN A;  3SYX A;  2YSZ A;  2EMT A;  1MAI A;  3TFM A;  2YRY A;  5EFX A;  4PQ0 A;  2FJL A;  1GC6 A;  4D0N B;  4EMO A;  1WI1 A;  2R0D A;  2YS1 A;  2W2X C;  4F7H A;  3PSC A;  2P0D A;  4A6K A;  3KZ1 A;  1UEF A;  2L2I A;  1X1F A;  2NMB A;  2GS0 A;  1RRP B;  2D9V A;  1U29 A;  4H8S A;  1P6S A;  2PZ1 A;  4YON A;  3GF9 A;  4KAX B;  3FSS A;  2MKR A;  4KHB B;  4MK0 A;  1U5E A;  1FAO A;  2ROZ B;  3UZT A;  4GMX B;  4A5K A;  4HAW B;  3PZD A;  3VOQ A;  1M7E A;  2DHI A;  2COA A;  4WJ7 A;  1TXD A;  3SUZ A;  1KZG A;  1E5W A;  1FGY A;  2LYD A;  1GC7 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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5FI1A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations