5JHG | Genus

Total Genus 125

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	125
sequence length	368
structure length	356
Chain Sequence	QNWQHTVGKDVVAGLTQREIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKENLMPREELARLFPNLPELIEIHNSWCEAMKKLREEGPIIKEISDLMLARFDGPAREELQQVAAQFCSYQSIALELIKTKQRKESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLESIIKHTEGGTSEHEKLCRARDQCREILKYVNEAVKQTENRHRLEGYQKRLDATALERASNPLAAEFKSLDLTTRKMIHEGPLTWRISKDKTLDLHVLLLEDLLVLLQKQDEKLLLKCHTFSPVLKLNAVLIRSVATDKRAFFIICTSKLGPPQIYELVALTSSDKNTWMELLEEAVRNA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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Time for openFile(/file/5d0e2d3656ae3462f4c0add6/pdb.gz): 1292 ms

reading 356 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

356 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 26 ms

Adding embedded #jmolscript: select ({0:355});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Signaling protein/transcription
source organism	Homo sapiens
publication title	Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and ARHGEF11 rcsb
molecule keywords	Rho guanine nucleotide exchange factor 11
total genus	125
structure length	356
sequence length	368
chains with identical sequence	E
ec nomenclature
pdb deposition date	2016-04-21

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00621	RhoGEF	RhoGEF domain
A	PF17838	PH_16	PH domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.900.10	Mainly Alpha	Up-down Bundle	Dbl Homology Domain; Chain A	Dbl homology (DH) domain	5jhgA01
2.30.29.30	Mainly Beta	Roll	PH-domain like	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	5jhgA02

2P0FA 4GYVA 5C6RA 2I5CA 2P8VA 3F5RA 5D3XA 3ODWA 2AL6A 1Q67A 2D9WA 5CLQB 2G35A 4K2OA 2YS3A 2DKPA 3PP2A 1OY2A 4WVFB 3X23A 3ZDTA 3SUZA 4GMXB 4GXBA 2VSZA 2D9XA 1I2HA 2YSZA 4ZRJA 2ROVA 3U8ZA 3FEHA 1J19A 3TO1A 4MK0A 3PG7A 2DYNA 4NSWA 4HDQA 4A5KA 1U5GA 2XQNM 2YS1A 4CYEA 2KCJA 3D8EA 3PVUA 3BINA 2UVMA 2YVCA 1KZ7A 4K17A 2JP2A 2DLWA 1DDVA 5KCVA 2Z0QA 2P0DA 2YT0A 4Y94A 1K5GB 3EO2A 1BAKA 1DBHA 3JV3A 1XR0B 2V76A 5JHHA 2EC1A 1I7AA 2R09A 1MIXA 2GCJA 4KHAA 4EMOA 3DXCA 3PVLA 1PLSA 2DHIA 1UNPA 3KRWA 2RVBB 1FGYA 2KGXB 4YONA 5L81A 1P3RA 2M14A 2BCJA 3SO6A 5D3YA 2MFQA 5CLLB 3QIJA 2X18A 1B55A 2I1JA 2YS5A 2I1KA 2YF0A 4A6FA 2DN6A 2D4QA 3M1IB 2COCA 3GYPA 4HATB 2HE7A 2Z0OA 5D3WA 5HE0A 2DYQA 4KAXB 3LJUX 1UNQA 1FAOA 1GC7A 2KUPA 4GZUA 2LYDA 2L1CA 2GCLA 1OQNA 4IOYX 1FGZA 1TQZA 2J59M 1M7EA 1FB8A 1UPRA 1AWEA 3ULBA 1ZVRA 4KHOA 3CXBB 5KQ4A 3P7ZA 1M7RA 1U5FA 3GF9A 4D0OA 2R0DA 5GOWB 2D9ZA 1V89A 2N23A 1EVHA 3OANA 1X1FA 2COFA 4KHBB 1NI2A 1E5WA 1H10A 3DXDA 3AU4A 2YT1A 1FHOA 4HB4B 2K2UA 5DH9B 3PZDA 4MY6A 2Z0PA 1X1GA 3ODXA 4P7IA 4EKUA 2IYBA 1UPQA 2LG1A 2UZRA 3HQCA 1MK7B 1NTVA 4IFSA 1TJ6A 2COAA 4B6HA 2FJLA 2I5FA 1Z87A 4GOUA 2ELBA 5EFXA 3A8PA 5D3VA 2RSGA 2CRFA 5C5BB 2DFKA 4WJ7A 5J3YA 1SHCA 3ODOA 4XWXA 4HDOA 4DX90 4TYZA 5JHGA 1BTNA 4CHMA 1P6SA 2CAYA 1WJMA 4A6FB 3D8DA 5LOPB 2CODA 3CIKA 1WVHA 5FI0A 4K2PA 4HB2B 1MIZB 2DA0A 1V88A 4HHVA 1ZM0A 2E2XA 1W1DA 5C79A 4TKNA 2QKMA 3NSUA 5DHFB 1X11A 3D8FA 1FHXA 1WJ1A 2D9VA 2MDXA 2J0KA 1XD4A 4EJNA 2P0HA 2DX5A 1XCGA 2HTHB 5DI9B 2DKQA 1KZGA 4D0NB 1PFJA 1U5DA 2D10A 4HAYB 3AJ4A 3ZVRA 2LOZA 2YRYA 1XX0A 1Y5OA 5DIFB 1DROA 1N3HA 3KZ1A 1V5MA 5KQ1A 1H4RA 4GPTB 3P6AA 5D27A 1RJ2A 3G9WA 1W1HA 2W2XC 2W2WA 2UZSA 4NY0A 3TW1A 2AEHA 3FSSA 3GYOA 3TCAA 4BBKA 2MKRA 1MAIA 5J3TA 1RRPB 1F5XA 3SNHA 4KVGB 3O96A 2OTXA 2NMBA 3SV1A 1LB1A 2OQBA 1WI1A 3KY9A 2DHKA 2J0JA 1Y19B 3PSCA 2N0YA 1TXDA 3WA0A 4K81A 4A6KA 4A6HA 3DXEA 1V5PA 2PZ1A 5HE2A 3KSYA 3RCPA 5HE3A 1U2BA 2D2QA 4F7UP 5JLJB 4HAUB 5LONB 1BTKA 4HB0B 4ZRIA 3SYXA 2VKIA 3PEGA 1WGQA 1PMSA 2GS0A 2H7EA 4DBBA 4ZRKA 5FI1A 4F7GA 4GMVA 4L6EA 5J3QA 1XKEA 1QC6A 3T06A 1V5UA 2L2IA 1BWNA 4F7HA 2Q13A 4H8SA 1DYNA 4HB3B 1J0WA 2J0MA 2LKOA 2K00A 3IVFA 3ML4A 2DTCA 2ELAA 4PNKA 2RNRB 2ADZA 4Z2MB 1EAZA 1WGUA 2RGNB 3FM8C 1MPHA 1DDMA 3TFMA 3TVVA 3VIAA 3HK0A 4WSFA 1U5EA 2H7DA 1ZC4B 3QBVB 4HAWB 3VOQA 2Y7BA 1UNRA 4MT7A 1K5DB 5HE1A 1X86A 1MK9B 2D9YA 1BY1A 3ULCA 2EMSA 5C16A 2D11A 4DXAB 2EMTA 3BJIA 3UZTA 3V5WA 5JP4A 1GG3A 1W1GA 2ROZB 4HAZB 3N7CA 2ZPYA 1WG7A 4HAXB 4DX8A 4CHJA 1X05A 1QQGA 2CY5A 1ZC3B 2QKLA 1EF1A 3HW2B 4Z2NA 2MWNB 1GC6A 5C5BA 4GN1A 1V61A 1ISNA 4HAVB 1AQCA 1SGHA 3A98B 1UEFA 2DX1A 4IAPA 3MPXA 1IRSA 1XODA 2RLOA 1NTYA 2NZ8B 1DDWA 3AU5A 3QWMA 1FHWA 1KI1B 2K2JA 1NU2A 1U27A 3PVWA 1U29A 2LULA 2DHJA 2CY4A 2GJYA 3MDBC 5DHAB 3U7DA 1OMWA 2KR9A 2EJ8A 1FOEA 1ZSQA 3A8QA 4PQ0A 2VRWB 2M38A 3WYFB 2Y8FA 2RUKB 1EGXA 1P5TA 3KRXA 2Y8GA 4C0AA 1LW3A 1MKEA 3F0WA 4YL8A 2IFSA 2W2XD 2LOXA
chains in the Genus database with same CATH superfamily

2P0FA 4GYVA 5C6RA 2I5CA 2P8VA 3F5RA 5D3XA 3ODWA 2AL6A 1Q67A 2D9WA 5CLQB 2G35A 2NBVA 4K2OA 2YS3A 2DKPA 3PP2A 1OY2A 4WVFB 3X23A 3ZDTA 3SUZA 4GMXB 4GXBA 2VSZA 2D9XA 1I2HA 2YSZA 4ZRJA 2ROVA 3U8ZA 3FEHA 1J19A 3TO1A 4MK0A 4KHBA 3PG7A 2DYNA 4NSWA 4HDQA 4A5KA 1U5GA 2XQNM 2YS1A 4CYEA 2KCJA 3D8EA 3PVUA 1MI1A 3BINA 2UVMA 1T77A 2YVCA 1KZ7A 4K17A 2JP2A 2DLWA 1DDVA 5KCVA 2Z0QA 2P0DA 2YT0A 4Y94A 1K5GB 2Z13A 3EO2A 1BAKA 1DBHA 3JV3A 1XR0B 2V76A 5JHHA 2FJUB 2EC1A 1I7AA 2R09A 1MIXA 2GCJA 4GNKB 4KHAA 4EMOA 3DXCA 3PVLA 1PLSA 2DHIA 1UNPA 3KRWA 2RVBB 1FGYA 2Z4DA 2KGXB 4YONA 5L81A 1P3RA 2M14A 2BCJA 3FVCA 5D3YA 2MFQA 5CLLB 3SO6A 3QIJA 2X18A 1B55A 2I1JA 2YS5A 2I1KA 2YF0A 4A6FA 2DN6A 2D4QA 3M1IB 2COCA 3GYPA 4HATB 2HE7A 2Z0OA 5D3WA 5HE0A 2DYQA 4KAXB 3LJUX 1UNQA 1FAOA 1GC7A 2KUPA 4HSIA 4GZUA 2LYDA 2L1CA 2GCLA 1OQNA 5I2MA 4IOYX 1FGZA 1TQZA 2J59M 1M7EA 1FB8A 1UPRA 1AWEA 3ULBA 1ZVRA 4KHOA 3CXBB 5KQ4A 3A58A 3P7ZA 1M7RA 1U5FA 3GF9A 4D0OA 2R0DA 5GOWB 5IRSA 2KUQA 2D9ZA 1V89A 2N23A 1EVHA 3OANA 1X1FA 2COFA 4KHBB 1NI2A 1E5WA 1H10A 3DXDA 3AU4A 2YT1A 1FHOA 4HB4B 2K2UA 5DH9B 3PZDA 4MY6A 2Z0PA 1X1GA 3ODXA 4P7IA 4EKUA 2IYBA 2KIEA 1UPQA 2LG1A 2UZRA 3HQCA 1MK7B 1NTVA 4IFSA 1TJ6A 2COAA 1ZYIA 4B6HA 2FJLA 2I5FA 1Z87A 4GOUA 2ELBA 5EFXA 3A8PA 5D3VA 2RSGA 2CRFA 5C5BB 2DFKA 4WJ7A 5J3YA 1SHCA 3ODOA 4XWXA 2Z14A 4HDOA 4DX90 4TYZA 5JHGA 1BTNA 4CHMA 1P6SA 2CAYA 1WJMA 4A6FB 3D8DA 5LOPB 2CODA 3CIKA 1WVHA 5FI0A 4K2PA 4D6WA 4HB2B 4QJ4B 1MIZB 2DA0A 1V88A 4HHVA 2KR0A 3DCXA 1ZM0A 2E2XA 1W1DA 5I2SA 5C79A 4TKNA 2QKMA 3NSUA 5DHFB 1X11A 3D8FA 1FHXA 1WJ1A 2D9VA 2MDXA 2J0KA 1XD4A 4EJNA 2P0HA 2DX5A 4L1RA 1XCGA 2HTHB 5DI9B 2DKQA 1KZGA 4D0NB 1PFJA 2ZKMX 1U5DA 2D10A 4HAYB 3AJ4A 3ZVRA 2R2YA 2LOZA 2YRYA 1XX0A 1Y5OA 4QXAB 5DIFB 1DROA 1N3HA 3NWDA 3KZ1A 1V5MA 2RRFA 5KQ1A 1H4RA 4GPTB 3P6AA 5D27A 1RJ2A 3G9WA 1W1HA 4OT1A 2W2XC 2W2WA 4OSNA 2UZSA 4NY0A 3TW1A 2AEHA 3FSSA 3GYOA 3TCAA 4BBKA 2MKRA 1MAIA 4CSQA 5J3TA 1RRPB 1F5XA 3SNHA 4KVGB 2KIGA 3O96A 2OTXA 2NMBA 3SV1A 5M4YB 2Z59A 1LB1A 2OQBA 1WI1A 3KY9A 2DHKA 2J0JA 1Y19B 3PSCA 2N0YA 1TXDA 3WA0A 4K81A 4A6KA 4A6HA 3DXEA 1V5PA 2PZ1A 3HIEA 5HE2A 3KSYA 3RCPA 5HE3A 1U2BA 2D2QA 4F7UP 5JLJB 4HAUB 5LONB 1BTKA 3U12A 4HB0B 4ZRIA 3SYXA 2VKIA 3OHMB 3PEGA 1WGQA 1PMSA 2GS0A 2H7EA 4DBBA 4ZRKA 5FI1A 4F7GA 4GMVA 4L6EA 5J3QA 1XKEA 1QC6A 3T06A 1V5UA 2L2IA 1BWNA 4F7HA 2Q13A 4H8SA 1DYNA 4HB3B 1J0WA 2J0MA 2LKOA 2K00A 3IVFA 3ML4A 2DTCA 2ELAA 4PNKA 2RNRB 2ADZA 4Z2MB 1EAZA 1WGUA 2RGNB 3FM8C 1MPHA 1DDMA 2K8EA 3TFMA 3TVVA 3VIAA 3HK0A 4WSFA 1U5EA 2H7DA 1ZC4B 3QBVB 4HAWB 3VOQA 4DIXA 2Y7BA 1UNRA 4MT7A 1K5DB 5HE1A 1X86A 1MK9B 2D9YA 1BY1A 3ULCA 2EMSA 5C16A 2D11A 4DXAB 2EMTA 3BJIA 3UZTA 3V5WA 5JP4A 4QJ3B 1GG3A 3NWFA 1W1GA 2ROZB 4HAZB 3N7CA 2ZPYA 1WG7A 4HAXB 4DX8A 4CHJA 1X05A 1QQGA 2K49A 2CY5A 3NW8A 1ZC3B 2QKLA 1EF1A 3HW2B 2YT2A 4Z2NA 2MWNB 1GC6A 5C5BA 4GN1A 1V61A 1ISNA 4HAVB 1AQCA 1SGHA 3A98B 1UEFA 2DX1A 4IAPA 3MPXA 1IRSA 2GUMA 1XODA 2RLOA 1NTYA 2NZ8B 1DDWA 3AU5A 3QWMA 1FHWA 1KI1B 2K2JA 1NU2A 3HSAA 1U27A 3PVWA 1U29A 2LULA 3NWAA 2DHJA 2CY4A 2GJYA 3MDBC 5DHAB 3U7DA 1OMWA 2KR9A 2EJ8A 1FOEA 1ZSQA 4QJ5B 3A8QA 4PQ0A 2VRWB 2M38A 3WYFB 5LG4B 2Y8FA 2RUKB 1EGXA 1P5TA 3KRXA 2Y8GA 4C0AA 1LW3A 1MKEA 3F0WA 3B77A 4YL8A 2IFSA 2W2XD 2LOXA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2P0F A;  4GYV A;  5C6R A;  2I5C A;  2P8V A;  3F5R A;  5D3X A;  3ODW A;  2AL6 A;  1Q67 A;  2D9W A;  5CLQ B;  2G35 A;  4K2O A;  2YS3 A;  2DKP A;  3PP2 A;  1OY2 A;  4WVF B;  3X23 A;  3ZDT A;  3SUZ A;  4GMX B;  4GXB A;  2VSZ A;  2D9X A;  1I2H A;  2YSZ A;  4ZRJ A;  2ROV A;  3U8Z A;  3FEH A;  1J19 A;  3TO1 A;  4MK0 A;  3PG7 A;  2DYN A;  4NSW A;  4HDQ A;  4A5K A;  1U5G A;  2XQN M;  2YS1 A;  4CYE A;  2KCJ A;  3D8E A;  3PVU A;  3BIN A;  2UVM A;  2YVC A;  1KZ7 A;  4K17 A;  2JP2 A;  2DLW A;  1DDV A;  5KCV A;  2Z0Q A;  2P0D A;  2YT0 A;  4Y94 A;  1K5G B;  3EO2 A;  1BAK A;  1DBH A;  3JV3 A;  1XR0 B;  2V76 A;  5JHH A;  2EC1 A;  1I7A A;  2R09 A;  1MIX A;  2GCJ A;  4KHA A;  4EMO A;  3DXC A;  3PVL A;  1PLS A;  2DHI A;  1UNP A;  3KRW A;  2RVB B;  1FGY A;  2KGX B;  4YON A;  5L81 A;  1P3R A;  2M14 A;  2BCJ A;  3SO6 A;  5D3Y A;  2MFQ A;  5CLL B;  3QIJ A;  2X18 A;  1B55 A;  2I1J A;  2YS5 A;  2I1K A;  2YF0 A;  4A6F A;  2DN6 A;  2D4Q A;  3M1I B;  2COC A;  3GYP A;  4HAT B;  2HE7 A;  2Z0O A;  5D3W A;  5HE0 A;  2DYQ A;  4KAX B;  3LJU X;  1UNQ A;  1FAO A;  1GC7 A;  2KUP A;  4GZU A;  2LYD A;  2L1C A;  2GCL A;  1OQN A;  4IOY X;  1FGZ A;  1TQZ A;  2J59 M;  1M7E A;  1FB8 A;  1UPR A;  1AWE A;  3ULB A;  1ZVR A;  4KHO A;  3CXB B;  5KQ4 A;  3P7Z A;  1M7R A;  1U5F A;  3GF9 A;  4D0O A;  2R0D A;  5GOW B;  2D9Z A;  1V89 A;  2N23 A;  1EVH A;  3OAN A;  1X1F A;  2COF A;  4KHB B;  1NI2 A;  1E5W A;  1H10 A;  3DXD A;  3AU4 A;  2YT1 A;  1FHO A;  4HB4 B;  2K2U A;  5DH9 B;  3PZD A;  4MY6 A;  2Z0P A;  1X1G A;  3ODX A;  4P7I A;  4EKU A;  2IYB A;  1UPQ A;  2LG1 A;  2UZR A;  3HQC A;  1MK7 B;  1NTV A;  4IFS A;  1TJ6 A;  2COA A;  4B6H A;  2FJL A;  2I5F A;  1Z87 A;  4GOU A;  2ELB A;  5EFX A;  3A8P A;  5D3V A;  2RSG A;  2CRF A;  5C5B B;  2DFK A;  4WJ7 A;  5J3Y A;  1SHC A;  3ODO A;  4XWX A;  4HDO A;  4DX9 0;  4TYZ A;  5JHG A;  1BTN A;  4CHM A;  1P6S A;  2CAY A;  1WJM A;  4A6F B;  3D8D A;  5LOP B;  2COD A;  3CIK A;  1WVH A;  5FI0 A;  4K2P A;  4HB2 B;  1MIZ B;  2DA0 A;  1V88 A;  4HHV A;  1ZM0 A;  2E2X A;  1W1D A;  5C79 A;  4TKN A;  2QKM A;  3NSU A;  5DHF B;  1X11 A;  3D8F A;  1FHX A;  1WJ1 A;  2D9V A;  2MDX A;  2J0K A;  1XD4 A;  4EJN A;  2P0H A;  2DX5 A;  1XCG A;  2HTH B;  5DI9 B;  2DKQ A;  1KZG A;  4D0N B;  1PFJ A;  1U5D A;  2D10 A;  4HAY B;  3AJ4 A;  3ZVR A;  2LOZ A;  2YRY A;  1XX0 A;  1Y5O A;  5DIF B;  1DRO A;  1N3H A;  3KZ1 A;  1V5M A;  5KQ1 A;  1H4R A;  4GPT B;  3P6A A;  5D27 A;  1RJ2 A;  3G9W A;  1W1H A;  2W2X C;  2W2W A;  2UZS A;  4NY0 A;  3TW1 A;  2AEH A;  3FSS A;  3GYO A;  3TCA A;  4BBK A;  2MKR A;  1MAI A;  5J3T A;  1RRP B;  1F5X A;  3SNH A;  4KVG B;  3O96 A;  2OTX A;  2NMB A;  3SV1 A;  1LB1 A;  2OQB A;  1WI1 A;  3KY9 A;  2DHK A;  2J0J A;  1Y19 B;  3PSC A;  2N0Y A;  1TXD A;  3WA0 A;  4K81 A;  4A6K A;  4A6H A;  3DXE A;  1V5P A;  2PZ1 A;  5HE2 A;  3KSY A;  3RCP A;  5HE3 A;  1U2B A;  2D2Q A;  4F7U P;  5JLJ B;  4HAU B;  5LON B;  1BTK A;  4HB0 B;  4ZRI A;  3SYX A;  2VKI A;  3PEG A;  1WGQ A;  1PMS A;  2GS0 A;  2H7E A;  4DBB A;  4ZRK A;  5FI1 A;  4F7G A;  4GMV A;  4L6E A;  5J3Q A;  1XKE A;  1QC6 A;  3T06 A;  1V5U A;  2L2I A;  1BWN A;  4F7H A;  2Q13 A;  4H8S A;  1DYN A;  4HB3 B;  1J0W A;  2J0M A;  2LKO A;  2K00 A;  3IVF A;  3ML4 A;  2DTC A;  2ELA A;  4PNK A;  2RNR B;  2ADZ A;  4Z2M B;  1EAZ A;  1WGU A;  2RGN B;  3FM8 C;  1MPH A;  1DDM A;  3TFM A;  3TVV A;  3VIA A;  3HK0 A;  4WSF A;  1U5E A;  2H7D A;  1ZC4 B;  3QBV B;  4HAW B;  3VOQ A;  2Y7B A;  1UNR A;  4MT7 A;  1K5D B;  5HE1 A;  1X86 A;  1MK9 B;  2D9Y A;  1BY1 A;  3ULC A;  2EMS A;  5C16 A;  2D11 A;  4DXA B;  2EMT A;  3BJI A;  3UZT A;  3V5W A;  5JP4 A;  1GG3 A;  1W1G A;  2ROZ B;  4HAZ B;  3N7C A;  2ZPY A;  1WG7 A;  4HAX B;  4DX8 A;  4CHJ A;  1X05 A;  1QQG A;  2CY5 A;  1ZC3 B;  2QKL A;  1EF1 A;  3HW2 B;  4Z2N A;  2MWN B;  1GC6 A;  5C5B A;  4GN1 A;  1V61 A;  1ISN A;  4HAV B;  1AQC A;  1SGH A;  3A98 B;  1UEF A;  2DX1 A;  4IAP A;  3MPX A;  1IRS A;  1XOD A;  2RLO A;  1NTY A;  2NZ8 B;  1DDW A;  3AU5 A;  3QWM A;  1FHW A;  1KI1 B;  2K2J A;  1NU2 A;  1U27 A;  3PVW A;  1U29 A;  2LUL A;  2DHJ A;  2CY4 A;  2GJY A;  3MDB C;  5DHA B;  3U7D A;  1OMW A;  2KR9 A;  2EJ8 A;  1FOE A;  1ZSQ A;  3A8Q A;  4PQ0 A;  2VRW B;  2M38 A;  3WYF B;  2Y8F A;  2RUK B;  1EGX A;  1P5T A;  3KRX A;  2Y8G A;  4C0A A;  1LW3 A;  1MKE A;  3F0W A;  4YL8 A;  2IFS A;  2W2X D;  2LOX A; 
#chains in the Genus database with same CATH topology
 2P0F A;  4GYV A;  5C6R A;  2I5C A;  2P8V A;  3F5R A;  5D3X A;  3ODW A;  2AL6 A;  1Q67 A;  2D9W A;  5CLQ B;  2G35 A;  2NBV A;  4K2O A;  2YS3 A;  2DKP A;  3PP2 A;  1OY2 A;  4WVF B;  3X23 A;  3ZDT A;  3SUZ A;  4GMX B;  4GXB A;  2VSZ A;  2D9X A;  1I2H A;  2YSZ A;  4ZRJ A;  2ROV A;  3U8Z A;  3FEH A;  1J19 A;  3TO1 A;  4MK0 A;  4KHB A;  3PG7 A;  2DYN A;  4NSW A;  4HDQ A;  4A5K A;  1U5G A;  2XQN M;  2YS1 A;  4CYE A;  2KCJ A;  3D8E A;  3PVU A;  1MI1 A;  3BIN A;  2UVM A;  1T77 A;  2YVC A;  1KZ7 A;  4K17 A;  2JP2 A;  2DLW A;  1DDV A;  5KCV A;  2Z0Q A;  2P0D A;  2YT0 A;  4Y94 A;  1K5G B;  2Z13 A;  3EO2 A;  1BAK A;  1DBH A;  3JV3 A;  1XR0 B;  2V76 A;  5JHH A;  2FJU B;  2EC1 A;  1I7A A;  2R09 A;  1MIX A;  2GCJ A;  4GNK B;  4KHA A;  4EMO A;  3DXC A;  3PVL A;  1PLS A;  2DHI A;  1UNP A;  3KRW A;  2RVB B;  1FGY A;  2Z4D A;  2KGX B;  4YON A;  5L81 A;  1P3R A;  2M14 A;  2BCJ A;  3FVC A;  5D3Y A;  2MFQ A;  5CLL B;  3SO6 A;  3QIJ A;  2X18 A;  1B55 A;  2I1J A;  2YS5 A;  2I1K A;  2YF0 A;  4A6F A;  2DN6 A;  2D4Q A;  3M1I B;  2COC A;  3GYP A;  4HAT B;  2HE7 A;  2Z0O A;  5D3W A;  5HE0 A;  2DYQ A;  4KAX B;  3LJU X;  1UNQ A;  1FAO A;  1GC7 A;  2KUP A;  4HSI A;  4GZU A;  2LYD A;  2L1C A;  2GCL A;  1OQN A;  5I2M A;  4IOY X;  1FGZ A;  1TQZ A;  2J59 M;  1M7E A;  1FB8 A;  1UPR A;  1AWE A;  3ULB A;  1ZVR A;  4KHO A;  3CXB B;  5KQ4 A;  3A58 A;  3P7Z A;  1M7R A;  1U5F A;  3GF9 A;  4D0O A;  2R0D A;  5GOW B;  5IRS A;  2KUQ A;  2D9Z A;  1V89 A;  2N23 A;  1EVH A;  3OAN A;  1X1F A;  2COF A;  4KHB B;  1NI2 A;  1E5W A;  1H10 A;  3DXD A;  3AU4 A;  2YT1 A;  1FHO A;  4HB4 B;  2K2U A;  5DH9 B;  3PZD A;  4MY6 A;  2Z0P A;  1X1G A;  3ODX A;  4P7I A;  4EKU A;  2IYB A;  2KIE A;  1UPQ A;  2LG1 A;  2UZR A;  3HQC A;  1MK7 B;  1NTV A;  4IFS A;  1TJ6 A;  2COA A;  1ZYI A;  4B6H A;  2FJL A;  2I5F A;  1Z87 A;  4GOU A;  2ELB A;  5EFX A;  3A8P A;  5D3V A;  2RSG A;  2CRF A;  5C5B B;  2DFK A;  4WJ7 A;  5J3Y A;  1SHC A;  3ODO A;  4XWX A;  2Z14 A;  4HDO A;  4DX9 0;  4TYZ A;  5JHG A;  1BTN A;  4CHM A;  1P6S A;  2CAY A;  1WJM A;  4A6F B;  3D8D A;  5LOP B;  2COD A;  3CIK A;  1WVH A;  5FI0 A;  4K2P A;  4D6W A;  4HB2 B;  4QJ4 B;  1MIZ B;  2DA0 A;  1V88 A;  4HHV A;  2KR0 A;  3DCX A;  1ZM0 A;  2E2X A;  1W1D A;  5I2S A;  5C79 A;  4TKN A;  2QKM A;  3NSU A;  5DHF B;  1X11 A;  3D8F A;  1FHX A;  1WJ1 A;  2D9V A;  2MDX A;  2J0K A;  1XD4 A;  4EJN A;  2P0H A;  2DX5 A;  4L1R A;  1XCG A;  2HTH B;  5DI9 B;  2DKQ A;  1KZG A;  4D0N B;  1PFJ A;  2ZKM X;  1U5D A;  2D10 A;  4HAY B;  3AJ4 A;  3ZVR A;  2R2Y A;  2LOZ A;  2YRY A;  1XX0 A;  1Y5O A;  4QXA B;  5DIF B;  1DRO A;  1N3H A;  3NWD A;  3KZ1 A;  1V5M A;  2RRF A;  5KQ1 A;  1H4R A;  4GPT B;  3P6A A;  5D27 A;  1RJ2 A;  3G9W A;  1W1H A;  4OT1 A;  2W2X C;  2W2W A;  4OSN A;  2UZS A;  4NY0 A;  3TW1 A;  2AEH A;  3FSS A;  3GYO A;  3TCA A;  4BBK A;  2MKR A;  1MAI A;  4CSQ A;  5J3T A;  1RRP B;  1F5X A;  3SNH A;  4KVG B;  2KIG A;  3O96 A;  2OTX A;  2NMB A;  3SV1 A;  5M4Y B;  2Z59 A;  1LB1 A;  2OQB A;  1WI1 A;  3KY9 A;  2DHK A;  2J0J A;  1Y19 B;  3PSC A;  2N0Y A;  1TXD A;  3WA0 A;  4K81 A;  4A6K A;  4A6H A;  3DXE A;  1V5P A;  2PZ1 A;  3HIE A;  5HE2 A;  3KSY A;  3RCP A;  5HE3 A;  1U2B A;  2D2Q A;  4F7U P;  5JLJ B;  4HAU B;  5LON B;  1BTK A;  3U12 A;  4HB0 B;  4ZRI A;  3SYX A;  2VKI A;  3OHM B;  3PEG A;  1WGQ A;  1PMS A;  2GS0 A;  2H7E A;  4DBB A;  4ZRK A;  5FI1 A;  4F7G A;  4GMV A;  4L6E A;  5J3Q A;  1XKE A;  1QC6 A;  3T06 A;  1V5U A;  2L2I A;  1BWN A;  4F7H A;  2Q13 A;  4H8S A;  1DYN A;  4HB3 B;  1J0W A;  2J0M A;  2LKO A;  2K00 A;  3IVF A;  3ML4 A;  2DTC A;  2ELA A;  4PNK A;  2RNR B;  2ADZ A;  4Z2M B;  1EAZ A;  1WGU A;  2RGN B;  3FM8 C;  1MPH A;  1DDM A;  2K8E A;  3TFM A;  3TVV A;  3VIA A;  3HK0 A;  4WSF A;  1U5E A;  2H7D A;  1ZC4 B;  3QBV B;  4HAW B;  3VOQ A;  4DIX A;  2Y7B A;  1UNR A;  4MT7 A;  1K5D B;  5HE1 A;  1X86 A;  1MK9 B;  2D9Y A;  1BY1 A;  3ULC A;  2EMS A;  5C16 A;  2D11 A;  4DXA B;  2EMT A;  3BJI A;  3UZT A;  3V5W A;  5JP4 A;  4QJ3 B;  1GG3 A;  3NWF A;  1W1G A;  2ROZ B;  4HAZ B;  3N7C A;  2ZPY A;  1WG7 A;  4HAX B;  4DX8 A;  4CHJ A;  1X05 A;  1QQG A;  2K49 A;  2CY5 A;  3NW8 A;  1ZC3 B;  2QKL A;  1EF1 A;  3HW2 B;  2YT2 A;  4Z2N A;  2MWN B;  1GC6 A;  5C5B A;  4GN1 A;  1V61 A;  1ISN A;  4HAV B;  1AQC A;  1SGH A;  3A98 B;  1UEF A;  2DX1 A;  4IAP A;  3MPX A;  1IRS A;  2GUM A;  1XOD A;  2RLO A;  1NTY A;  2NZ8 B;  1DDW A;  3AU5 A;  3QWM A;  1FHW A;  1KI1 B;  2K2J A;  1NU2 A;  3HSA A;  1U27 A;  3PVW A;  1U29 A;  2LUL A;  3NWA A;  2DHJ A;  2CY4 A;  2GJY A;  3MDB C;  5DHA B;  3U7D A;  1OMW A;  2KR9 A;  2EJ8 A;  1FOE A;  1ZSQ A;  4QJ5 B;  3A8Q A;  4PQ0 A;  2VRW B;  2M38 A;  3WYF B;  5LG4 B;  2Y8F A;  2RUK B;  1EGX A;  1P5T A;  3KRX A;  2Y8G A;  4C0A A;  1LW3 A;  1MKE A;  3F0W A;  3B77 A;  4YL8 A;  2IFS A;  2W2X D;  2LOX A; 
#chains in the Genus database with same CATH homology
 2P0F A;  4GYV A;  5C6R A;  2I5C A;  2P8V A;  3F5R A;  5D3X A;  3ODW A;  2AL6 A;  1Q67 A;  2D9W A;  5CLQ B;  2G35 A;  4K2O A;  2YS3 A;  2DKP A;  3PP2 A;  1OY2 A;  4WVF B;  3X23 A;  3ZDT A;  3SUZ A;  4GMX B;  4GXB A;  2VSZ A;  2D9X A;  1I2H A;  2YSZ A;  4ZRJ A;  2ROV A;  3U8Z A;  3FEH A;  1J19 A;  3TO1 A;  4MK0 A;  3PG7 A;  2DYN A;  4NSW A;  4HDQ A;  4A5K A;  1U5G A;  2XQN M;  2YS1 A;  4CYE A;  2KCJ A;  3D8E A;  3PVU A;  3BIN A;  2UVM A;  2YVC A;  1KZ7 A;  4K17 A;  2JP2 A;  2DLW A;  1DDV A;  5KCV A;  2Z0Q A;  2P0D A;  2YT0 A;  4Y94 A;  1K5G B;  3EO2 A;  1BAK A;  1DBH A;  3JV3 A;  1XR0 B;  2V76 A;  5JHH A;  2EC1 A;  1I7A A;  2R09 A;  1MIX A;  2GCJ A;  4KHA A;  4EMO A;  3DXC A;  3PVL A;  1PLS A;  2DHI A;  1UNP A;  3KRW A;  2RVB B;  1FGY A;  2KGX B;  4YON A;  5L81 A;  1P3R A;  2M14 A;  2BCJ A;  3SO6 A;  5D3Y A;  2MFQ A;  5CLL B;  3QIJ A;  2X18 A;  1B55 A;  2I1J A;  2YS5 A;  2I1K A;  2YF0 A;  4A6F A;  2DN6 A;  2D4Q A;  3M1I B;  2COC A;  3GYP A;  4HAT B;  2HE7 A;  2Z0O A;  5D3W A;  5HE0 A;  2DYQ A;  4KAX B;  3LJU X;  1UNQ A;  1FAO A;  1GC7 A;  2KUP A;  4GZU A;  2LYD A;  2L1C A;  2GCL A;  1OQN A;  4IOY X;  1FGZ A;  1TQZ A;  2J59 M;  1M7E A;  1FB8 A;  1UPR A;  1AWE A;  3ULB A;  1ZVR A;  4KHO A;  3CXB B;  5KQ4 A;  3P7Z A;  1M7R A;  1U5F A;  3GF9 A;  4D0O A;  2R0D A;  5GOW B;  2D9Z A;  1V89 A;  2N23 A;  1EVH A;  3OAN A;  1X1F A;  2COF A;  4KHB B;  1NI2 A;  1E5W A;  1H10 A;  3DXD A;  3AU4 A;  2YT1 A;  1FHO A;  4HB4 B;  2K2U A;  5DH9 B;  3PZD A;  4MY6 A;  2Z0P A;  1X1G A;  3ODX A;  4P7I A;  4EKU A;  2IYB A;  1UPQ A;  2LG1 A;  2UZR A;  3HQC A;  1MK7 B;  1NTV A;  4IFS A;  1TJ6 A;  2COA A;  4B6H A;  2FJL A;  2I5F A;  1Z87 A;  4GOU A;  2ELB A;  5EFX A;  3A8P A;  5D3V A;  2RSG A;  2CRF A;  5C5B B;  2DFK A;  4WJ7 A;  5J3Y A;  1SHC A;  3ODO A;  4XWX A;  4HDO A;  4DX9 0;  4TYZ A;  5JHG A;  1BTN A;  4CHM A;  1P6S A;  2CAY A;  1WJM A;  4A6F B;  3D8D A;  5LOP B;  2COD A;  3CIK A;  1WVH A;  5FI0 A;  4K2P A;  4HB2 B;  1MIZ B;  2DA0 A;  1V88 A;  4HHV A;  1ZM0 A;  2E2X A;  1W1D A;  5C79 A;  4TKN A;  2QKM A;  3NSU A;  5DHF B;  1X11 A;  3D8F A;  1FHX A;  1WJ1 A;  2D9V A;  2MDX A;  2J0K A;  1XD4 A;  4EJN A;  2P0H A;  2DX5 A;  1XCG A;  2HTH B;  5DI9 B;  2DKQ A;  1KZG A;  4D0N B;  1PFJ A;  1U5D A;  2D10 A;  4HAY B;  3AJ4 A;  3ZVR A;  2LOZ A;  2YRY A;  1XX0 A;  1Y5O A;  5DIF B;  1DRO A;  1N3H A;  3KZ1 A;  1V5M A;  5KQ1 A;  1H4R A;  4GPT B;  3P6A A;  5D27 A;  1RJ2 A;  3G9W A;  1W1H A;  2W2X C;  2W2W A;  2UZS A;  4NY0 A;  3TW1 A;  2AEH A;  3FSS A;  3GYO A;  3TCA A;  4BBK A;  2MKR A;  1MAI A;  5J3T A;  1RRP B;  1F5X A;  3SNH A;  4KVG B;  3O96 A;  2OTX A;  2NMB A;  3SV1 A;  1LB1 A;  2OQB A;  1WI1 A;  3KY9 A;  2DHK A;  2J0J A;  1Y19 B;  3PSC A;  2N0Y A;  1TXD A;  3WA0 A;  4K81 A;  4A6K A;  4A6H A;  3DXE A;  1V5P A;  2PZ1 A;  5HE2 A;  3KSY A;  3RCP A;  5HE3 A;  1U2B A;  2D2Q A;  4F7U P;  5JLJ B;  4HAU B;  5LON B;  1BTK A;  4HB0 B;  4ZRI A;  3SYX A;  2VKI A;  3PEG A;  1WGQ A;  1PMS A;  2GS0 A;  2H7E A;  4DBB A;  4ZRK A;  5FI1 A;  4F7G A;  4GMV A;  4L6E A;  5J3Q A;  1XKE A;  1QC6 A;  3T06 A;  1V5U A;  2L2I A;  1BWN A;  4F7H A;  2Q13 A;  4H8S A;  1DYN A;  4HB3 B;  1J0W A;  2J0M A;  2LKO A;  2K00 A;  3IVF A;  3ML4 A;  2DTC A;  2ELA A;  4PNK A;  2RNR B;  2ADZ A;  4Z2M B;  1EAZ A;  1WGU A;  2RGN B;  3FM8 C;  1MPH A;  1DDM A;  3TFM A;  3TVV A;  3VIA A;  3HK0 A;  4WSF A;  1U5E A;  2H7D A;  1ZC4 B;  3QBV B;  4HAW B;  3VOQ A;  2Y7B A;  1UNR A;  4MT7 A;  1K5D B;  5HE1 A;  1X86 A;  1MK9 B;  2D9Y A;  1BY1 A;  3ULC A;  2EMS A;  5C16 A;  2D11 A;  4DXA B;  2EMT A;  3BJI A;  3UZT A;  3V5W A;  5JP4 A;  1GG3 A;  1W1G A;  2ROZ B;  4HAZ B;  3N7C A;  2ZPY A;  1WG7 A;  4HAX B;  4DX8 A;  4CHJ A;  1X05 A;  1QQG A;  2CY5 A;  1ZC3 B;  2QKL A;  1EF1 A;  3HW2 B;  4Z2N A;  2MWN B;  1GC6 A;  5C5B A;  4GN1 A;  1V61 A;  1ISN A;  4HAV B;  1AQC A;  1SGH A;  3A98 B;  1UEF A;  2DX1 A;  4IAP A;  3MPX A;  1IRS A;  1XOD A;  2RLO A;  1NTY A;  2NZ8 B;  1DDW A;  3AU5 A;  3QWM A;  1FHW A;  1KI1 B;  2K2J A;  1NU2 A;  1U27 A;  3PVW A;  1U29 A;  2LUL A;  2DHJ A;  2CY4 A;  2GJY A;  3MDB C;  5DHA B;  3U7D A;  1OMW A;  2KR9 A;  2EJ8 A;  1FOE A;  1ZSQ A;  3A8Q A;  4PQ0 A;  2VRW B;  2M38 A;  3WYF B;  2Y8F A;  2RUK B;  1EGX A;  1P5T A;  3KRX A;  2Y8G A;  4C0A A;  1LW3 A;  1MKE A;  3F0W A;  4YL8 A;  2IFS A;  2W2X D;  2LOX A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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5JHGA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations