5JHG | Genus

Total Genus 125

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	125
sequence length	368
structure length	356
Chain Sequence	QNWQHTVGKDVVAGLTQREIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKENLMPREELARLFPNLPELIEIHNSWCEAMKKLREEGPIIKEISDLMLARFDGPAREELQQVAAQFCSYQSIALELIKTKQRKESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLESIIKHTEGGTSEHEKLCRARDQCREILKYVNEAVKQTENRHRLEGYQKRLDATALERASNPLAAEFKSLDLTTRKMIHEGPLTWRISKDKTLDLHVLLLEDLLVLLQKQDEKLLLKCHTFSPVLKLNAVLIRSVATDKRAFFIICTSKLGPPQIYELVALTSSDKNTWMELLEEAVRNA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 356 atoms

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356 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Signaling protein/transcription
source organism	Homo sapiens
publication title	Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and ARHGEF11 rcsb
molecule keywords	Rho guanine nucleotide exchange factor 11
total genus	125
structure length	356
sequence length	368
chains with identical sequence	E
ec nomenclature
pdb deposition date	2016-04-21

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00621	RhoGEF	RhoGEF domain
A	PF17838	PH_16	PH domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.900.10	Mainly Alpha	Up-down Bundle	Dbl Homology Domain; Chain A	Dbl homology (DH) domain	5jhgA01
2.30.29.30	Mainly Beta	Roll	PH-domain like	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	5jhgA02

2FJLA 1SGHA 3PVLA 5CLQB 1N3HA 3ULCA 1X11A 1MAIA 2K2JA 3P7ZA 4K2OA 3FSSA 2D2QA 4ZRJA 2J0MA 5JLJB 3A8QA 1KZ7A 2YS5A 4WVFB 1Z87A 1UPQA 1QQGA 1U2BA 4HDQA 4B6HA 2DA0A 2KUPA 3AU5A 3NSUA 2I1KA 3TVVA 4CHJA 2IFSA 2GCJA 3U7DA 2NZ8B 3G9WA 2ADZA 2NMBA 1W1DA 4DXAB 4D0OA 2M14A 2DHIA 1NU2A 4IOYX 4A6HA 2ROZB 3T06A 3ODWA 4ZRKA 3WA0A 2HE7A 4KAXB 4GPTB 1Y5OA 4Z2NA 1MPHA 2G35A 2HTHB 2R0DA 4TYZA 3VOQA 1M7EA 4A6FB 2YS3A 5J3QA 1V61A 1WGQA 3V5WA 2ELAA 2OQBA 1K5GB 3PZDA 3PEGA 2DN6A 2YF0A 1V5UA 3A98B 4F7HA 4GN1A 3AU4A 1I2HA 1FB8A 3D8EA 2VRWB 2Q13A 1OQNA 3HK0A 4HB3B 2EJ8A 5D3YA 2DTCA 3ODOA 1U29A 2P0FA 2I5FA 3HQCA 2GCLA 4PQ0A 2RLOA 2ELBA 4H8SA 1FHXA 1XX0A 4K2PA 4GZUA 1ISNA 3KSYA 2W2WA 2RNRB 2MFQA 4HB4B 2KR9A 1LB1A 4A5KA 3AJ4A 4HAUB 2AL6A 1PFJA 4DX8A 3ZVRA 3SUZA 1XD4A 1EAZA 2QKMA 4F7UP 3PG7A 2Y8FA 1V5PA 5D3XA 4HB0B 4P7IA 1MIXA 5D27A 1WJMA 3PVUA 3ODXA 4NY0A 2LG1A 4KHAA 5KQ1A 2H7EA 3MPXA 3GF9A 1KI1B 3WYFB 1U5DA 2CAYA 4K17A 4YL8A 2EMTA 2D10A 1GC6A 1UNPA 2YVCA 2DX5A 2UZSA 1DYNA 1P3RA 3A8PA 5J3YA 1U5EA 2P8VA 4HAZB 1Q67A 5JHGA 1SHCA 1U5FA 4KVGB 3IVFA 2DFKA 1X1GA 4GMXB 2D9VA 4IFSA 1DBHA 2P0DA 2OTXA 4WSFA 4GXBA 1WVHA 1V88A 3VIAA 2ROVA 5KCVA 2LULA 4A6FA 5DIFB 1BWNA 3N7CA 2ZPYA 1NTYA 5DHFB 3P6AA 1QC6A 4TKNA 4Z2MB 3DXCA 4GMVA 1FOEA 5JP4A 5C16A 1FAOA 4YONA 1DDMA 4Y94A 4MT7A 2LOZA 4HAWB 5D3WA 1UEFA 2R09A 3KZ1A 3DXDA 2EMSA 3KRXA 3SYXA 2VSZA 1EGXA 1ZM0A 2YT1A 3GYPA 5LONB 5HE1A 1F5XA 5C5BB 2DHKA 3ZDTA 4MK0A 5C79A 4HAXB 1W1GA 3U8ZA 3BINA 5JHHA 4KHOA 2DYNA 2AEHA 5FI0A 2W2XD 4XWXA 5L81A 3D8FA 3M1IB 1RRPB 2MKRA 1DROA 1ZSQA 1EF1A 2Y8GA 2YS1A 1M7RA 1UNQA 3CXBB 2Y7BA 2DKQA 5DH9B 5C6RA 2K00A 4CHMA 1MK7B 1BTNA 1FGYA 1U27A 2GJYA 3D8DA 2L2IA 1J0WA 2BCJA 1MKEA 2XQNM 1NI2A 1PMSA 1DDWA 2EC1A 2J0JA 3F5RA 1V89A 2RSGA 1DDVA 3ULBA 1XR0B 2YRYA 2JP2A 1H4RA 1MIZB 4ZRIA 1W1HA 3TFMA 1BAKA 2GS0A 3FM8C 4HATB 4EKUA 1P5TA 1BTKA 2CODA 3JV3A 3PSCA 1X1FA 3CIKA 5HE0A 1GC7A 1XCGA 1U5GA 3MDBC 4HAYB 4HB2B 1K5DB 1UPRA 2X18A 2DX1A 3EO2A 3KRWA 4MY6A 3FEHA 2W2XC 2VKIA 3RCPA 1LW3A 2KGXB 2CY5A 4GOUA 1TXDA 2N0YA 2PZ1A 2K2UA 1OMWA 2MDXA 1IRSA 2D9YA 2LOXA 4D0NB 1RJ2A 4C0AA 2Z0PA 2V76A 2I5CA 3PVWA 1I7AA 4EMOA 4BBKA 4F7GA 2D9ZA 1MK9B 1ZC3B 3DXEA 2D4QA 1X05A 2DKPA 5KQ4A 1WG7A 1NTVA 2COAA 4CYEA 5DI9B 3KY9A 3SO6A 5C5BA 5J3TA 3QIJA 1J19A 3OANA 4KHBB 3HW2B 1V5MA 2CY4A 2IYBA 4L6EA 2LYDA 5GOWB 5CLLB 5LOPB 1EVHA 2COCA 3O96A 2Z0OA 5HE2A 4HHVA 3BJIA 4HDOA 4K81A 2Z0QA 4EJNA 2RGNB 2QKLA 1AQCA 1BY1A 2KCJA 1ZC4B 1GG3A 2UZRA 2E2XA 2N23A 4PNKA 2CRFA 3GYOA 2RVBB 1FHOA 2DHJA 1TQZA 2H7DA 3ML4A 2J0KA 2UVMA 3X23A 2P0HA 2D11A 3UZTA 1XKEA 2L1CA 2YT0A 3TCAA 3QWMA 1WI1A 3LJUX 1X86A 5FI1A 4HAVB 2DLWA 2LKOA 1UNRA 3QBVB 2J59M 3TO1A 1E5WA 1FHWA 4NSWA 1TJ6A 4DX90 2MWNB 2I1JA 5HE3A 1OY2A 5DHAB 3SV1A 1P6SA 1WGUA 2D9WA 3TW1A 2COFA 1FGZA 1XODA 3F0WA 1AWEA 1Y19B 1ZVRA 2DYQA 3SNHA 1B55A 4GYVA 5D3VA 1PLSA 2M38A 2YSZA 1KZGA 2D9XA 1WJ1A 3PP2A 5EFXA 4WJ7A 1H10A 4A6KA 4DBBA 4IAPA 2RUKB
chains in the Genus database with same CATH superfamily

2FJLA 1SGHA 3PVLA 5CLQB 1N3HA 2Z4DA 3ULCA 1X11A 1MAIA 2K2JA 3P7ZA 4K2OA 4KHBA 3FSSA 2D2QA 4ZRJA 2J0MA 5JLJB 3A8QA 1KZ7A 2YS5A 4WVFB 1Z87A 1UPQA 1QQGA 1U2BA 3B77A 5LG4B 4HDQA 4B6HA 4DIXA 2DA0A 2KUPA 3AU5A 3NSUA 2I1KA 3TVVA 4CHJA 2IFSA 2GCJA 3U7DA 2NZ8B 3G9WA 2ADZA 2NMBA 1W1DA 4DXAB 4D0OA 2M14A 2DHIA 1NU2A 4IOYX 4A6HA 2ROZB 3T06A 3ODWA 4ZRKA 3WA0A 2HE7A 4KAXB 4GPTB 1Y5OA 4Z2NA 1MPHA 2G35A 2HTHB 2R0DA 4TYZA 3VOQA 1M7EA 4A6FB 2YS3A 5J3QA 1V61A 1WGQA 2GUMA 3V5WA 2ELAA 2OQBA 1K5GB 3PZDA 3PEGA 2DN6A 2YF0A 1V5UA 3A98B 4F7HA 4GN1A 3AU4A 3U12A 1I2HA 1FB8A 3D8EA 2VRWB 2Q13A 1OQNA 3HK0A 4HB3B 2EJ8A 5D3YA 2DTCA 3ODOA 1U29A 2P0FA 2I5FA 3HQCA 2GCLA 4PQ0A 2RLOA 2ELBA 4H8SA 1FHXA 1XX0A 4K2PA 4CSQA 4GZUA 1ISNA 3KSYA 2W2WA 3HIEA 2RNRB 2MFQA 4HB4B 2KR9A 1LB1A 4A5KA 3AJ4A 4HAUB 4QXAB 2AL6A 1PFJA 4DX8A 3ZVRA 3SUZA 1XD4A 1EAZA 2QKMA 2NBVA 4F7UP 3PG7A 2Y8FA 1V5PA 5D3XA 4HB0B 4P7IA 1MIXA 5D27A 1WJMA 3PVUA 3ODXA 4NY0A 2KUQA 2LG1A 4KHAA 3DCXA 5KQ1A 2H7EA 3MPXA 3GF9A 3NWAA 2FJUB 1KI1B 3WYFB 1U5DA 2CAYA 4K17A 4YL8A 2EMTA 2D10A 1GC6A 1UNPA 2YVCA 2DX5A 2UZSA 1DYNA 1P3RA 3A8PA 5J3YA 1U5EA 2P8VA 4HAZB 1Q67A 5JHGA 1SHCA 1U5FA 4KVGB 4D6WA 3IVFA 2DFKA 1X1GA 4GMXB 2D9VA 4IFSA 1DBHA 2P0DA 2OTXA 4WSFA 4GXBA 1WVHA 1V88A 4GNKB 3VIAA 2ROVA 5KCVA 2KR0A 2LULA 4A6FA 5DIFB 1BWNA 3N7CA 2ZPYA 1NTYA 5DHFB 3P6AA 1QC6A 4TKNA 4QJ3B 4Z2MB 3DXCA 4GMVA 1FOEA 5JP4A 5C16A 1FAOA 4YONA 2Z59A 1DDMA 2YT2A 4Y94A 4MT7A 2LOZA 4HAWB 5D3WA 1UEFA 2R09A 3KZ1A 3DXDA 2EMSA 3KRXA 3SYXA 2VSZA 1EGXA 1ZM0A 2Z13A 2YT1A 3GYPA 5LONB 5HE1A 1F5XA 5C5BB 2DHKA 3ZDTA 4MK0A 5C79A 4HAXB 1W1GA 3U8ZA 3BINA 5JHHA 3HSAA 4KHOA 2DYNA 2AEHA 5FI0A 2R2YA 2W2XD 4XWXA 3D8FA 5L81A 3M1IB 2ZKMX 1RRPB 2MKRA 1DROA 1ZSQA 1EF1A 2Y8GA 2YS1A 1M7RA 1MI1A 1UNQA 3CXBB 2Y7BA 4OT1A 5IRSA 2DKQA 5DH9B 5C6RA 4HSIA 2RRFA 2K00A 4CHMA 1MK7B 1BTNA 1FGYA 1U27A 2GJYA 3D8DA 2L2IA 1J0WA 2BCJA 1MKEA 2XQNM 1NI2A 1PMSA 1DDWA 2KIGA 2EC1A 2J0JA 3F5RA 1V89A 2RSGA 1DDVA 3ULBA 1XR0B 2YRYA 3A58A 1ZYIA 1H4RA 2JP2A 1MIZB 4ZRIA 1W1HA 3TFMA 1BAKA 2GS0A 3FM8C 4HATB 4EKUA 1P5TA 1BTKA 2CODA 3JV3A 3PSCA 1X1FA 5I2MA 3CIKA 4OSNA 5HE0A 1GC7A 1XCGA 1U5GA 3MDBC 4HAYB 4HB2B 1K5DB 1UPRA 2X18A 2DX1A 3EO2A 3KRWA 4MY6A 3FEHA 2W2XC 2VKIA 3RCPA 1LW3A 2KGXB 2CY5A 4GOUA 1TXDA 2N0YA 2PZ1A 2K2UA 1OMWA 2MDXA 1IRSA 2D9YA 2LOXA 4D0NB 1RJ2A 4C0AA 2Z0PA 2K8EA 2V76A 2I5CA 3PVWA 1I7AA 4EMOA 4BBKA 4F7GA 2K49A 2D9ZA 3NW8A 1MK9B 2Z14A 1ZC3B 3DXEA 2D4QA 1X05A 2DKPA 5KQ4A 1WG7A 1NTVA 2COAA 4CYEA 5DI9B 3KY9A 3SO6A 5C5BA 5J3TA 3QIJA 1J19A 3OANA 4KHBB 3HW2B 1V5MA 2CY4A 2IYBA 5M4YB 4L6EA 2LYDA 5GOWB 5I2SA 5CLLB 3OHMB 5LOPB 1EVHA 2COCA 3O96A 1T77A 2Z0OA 5HE2A 4HHVA 3BJIA 4HDOA 4K81A 2Z0QA 4EJNA 2RGNB 2QKLA 1AQCA 1BY1A 2KCJA 1ZC4B 1GG3A 2UZRA 2E2XA 2N23A 4PNKA 2CRFA 3GYOA 2RVBB 1FHOA 3NWDA 2DHJA 1TQZA 2H7DA 3ML4A 4L1RA 2J0KA 2UVMA 3X23A 2P0HA 2D11A 3UZTA 1XKEA 2L1CA 2YT0A 3TCAA 3QWMA 1WI1A 3LJUX 1X86A 5FI1A 4HAVB 2DLWA 2LKOA 1UNRA 3QBVB 2J59M 3NWFA 4QJ4B 3TO1A 1E5WA 1FHWA 4NSWA 1TJ6A 4DX90 2MWNB 2I1JA 5HE3A 1OY2A 5DHAB 3SV1A 1P6SA 1WGUA 2D9WA 3TW1A 2COFA 1FGZA 1XODA 3F0WA 1AWEA 1Y19B 4QJ5B 1ZVRA 2KIEA 2DYQA 3SNHA 1B55A 4GYVA 5D3VA 1PLSA 2M38A 2YSZA 1KZGA 2D9XA 1WJ1A 3PP2A 5EFXA 3FVCA 4WJ7A 1H10A 4A6KA 4DBBA 4IAPA 2RUKB
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2FJL A;  1SGH A;  3PVL A;  5CLQ B;  1N3H A;  3ULC A;  1X11 A;  1MAI A;  2K2J A;  3P7Z A;  4K2O A;  3FSS A;  2D2Q A;  4ZRJ A;  2J0M A;  5JLJ B;  3A8Q A;  1KZ7 A;  2YS5 A;  4WVF B;  1Z87 A;  1UPQ A;  1QQG A;  1U2B A;  4HDQ A;  4B6H A;  2DA0 A;  2KUP A;  3AU5 A;  3NSU A;  2I1K A;  3TVV A;  4CHJ A;  2IFS A;  2GCJ A;  3U7D A;  2NZ8 B;  3G9W A;  2ADZ A;  2NMB A;  1W1D A;  4DXA B;  4D0O A;  2M14 A;  2DHI A;  1NU2 A;  4IOY X;  4A6H A;  2ROZ B;  3T06 A;  3ODW A;  4ZRK A;  3WA0 A;  2HE7 A;  4KAX B;  4GPT B;  1Y5O A;  4Z2N A;  1MPH A;  2G35 A;  2HTH B;  2R0D A;  4TYZ A;  3VOQ A;  1M7E A;  4A6F B;  2YS3 A;  5J3Q A;  1V61 A;  1WGQ A;  3V5W A;  2ELA A;  2OQB A;  1K5G B;  3PZD A;  3PEG A;  2DN6 A;  2YF0 A;  1V5U A;  3A98 B;  4F7H A;  4GN1 A;  3AU4 A;  1I2H A;  1FB8 A;  3D8E A;  2VRW B;  2Q13 A;  1OQN A;  3HK0 A;  4HB3 B;  2EJ8 A;  5D3Y A;  2DTC A;  3ODO A;  1U29 A;  2P0F A;  2I5F A;  3HQC A;  2GCL A;  4PQ0 A;  2RLO A;  2ELB A;  4H8S A;  1FHX A;  1XX0 A;  4K2P A;  4GZU A;  1ISN A;  3KSY A;  2W2W A;  2RNR B;  2MFQ A;  4HB4 B;  2KR9 A;  1LB1 A;  4A5K A;  3AJ4 A;  4HAU B;  2AL6 A;  1PFJ A;  4DX8 A;  3ZVR A;  3SUZ A;  1XD4 A;  1EAZ A;  2QKM A;  4F7U P;  3PG7 A;  2Y8F A;  1V5P A;  5D3X A;  4HB0 B;  4P7I A;  1MIX A;  5D27 A;  1WJM A;  3PVU A;  3ODX A;  4NY0 A;  2LG1 A;  4KHA A;  5KQ1 A;  2H7E A;  3MPX A;  3GF9 A;  1KI1 B;  3WYF B;  1U5D A;  2CAY A;  4K17 A;  4YL8 A;  2EMT A;  2D10 A;  1GC6 A;  1UNP A;  2YVC A;  2DX5 A;  2UZS A;  1DYN A;  1P3R A;  3A8P A;  5J3Y A;  1U5E A;  2P8V A;  4HAZ B;  1Q67 A;  5JHG A;  1SHC A;  1U5F A;  4KVG B;  3IVF A;  2DFK A;  1X1G A;  4GMX B;  2D9V A;  4IFS A;  1DBH A;  2P0D A;  2OTX A;  4WSF A;  4GXB A;  1WVH A;  1V88 A;  3VIA A;  2ROV A;  5KCV A;  2LUL A;  4A6F A;  5DIF B;  1BWN A;  3N7C A;  2ZPY A;  1NTY A;  5DHF B;  3P6A A;  1QC6 A;  4TKN A;  4Z2M B;  3DXC A;  4GMV A;  1FOE A;  5JP4 A;  5C16 A;  1FAO A;  4YON A;  1DDM A;  4Y94 A;  4MT7 A;  2LOZ A;  4HAW B;  5D3W A;  1UEF A;  2R09 A;  3KZ1 A;  3DXD A;  2EMS A;  3KRX A;  3SYX A;  2VSZ A;  1EGX A;  1ZM0 A;  2YT1 A;  3GYP A;  5LON B;  5HE1 A;  1F5X A;  5C5B B;  2DHK A;  3ZDT A;  4MK0 A;  5C79 A;  4HAX B;  1W1G A;  3U8Z A;  3BIN A;  5JHH A;  4KHO A;  2DYN A;  2AEH A;  5FI0 A;  2W2X D;  4XWX A;  5L81 A;  3D8F A;  3M1I B;  1RRP B;  2MKR A;  1DRO A;  1ZSQ A;  1EF1 A;  2Y8G A;  2YS1 A;  1M7R A;  1UNQ A;  3CXB B;  2Y7B A;  2DKQ A;  5DH9 B;  5C6R A;  2K00 A;  4CHM A;  1MK7 B;  1BTN A;  1FGY A;  1U27 A;  2GJY A;  3D8D A;  2L2I A;  1J0W A;  2BCJ A;  1MKE A;  2XQN M;  1NI2 A;  1PMS A;  1DDW A;  2EC1 A;  2J0J A;  3F5R A;  1V89 A;  2RSG A;  1DDV A;  3ULB A;  1XR0 B;  2YRY A;  2JP2 A;  1H4R A;  1MIZ B;  4ZRI A;  1W1H A;  3TFM A;  1BAK A;  2GS0 A;  3FM8 C;  4HAT B;  4EKU A;  1P5T A;  1BTK A;  2COD A;  3JV3 A;  3PSC A;  1X1F A;  3CIK A;  5HE0 A;  1GC7 A;  1XCG A;  1U5G A;  3MDB C;  4HAY B;  4HB2 B;  1K5D B;  1UPR A;  2X18 A;  2DX1 A;  3EO2 A;  3KRW A;  4MY6 A;  3FEH A;  2W2X C;  2VKI A;  3RCP A;  1LW3 A;  2KGX B;  2CY5 A;  4GOU A;  1TXD A;  2N0Y A;  2PZ1 A;  2K2U A;  1OMW A;  2MDX A;  1IRS A;  2D9Y A;  2LOX A;  4D0N B;  1RJ2 A;  4C0A A;  2Z0P A;  2V76 A;  2I5C A;  3PVW A;  1I7A A;  4EMO A;  4BBK A;  4F7G A;  2D9Z A;  1MK9 B;  1ZC3 B;  3DXE A;  2D4Q A;  1X05 A;  2DKP A;  5KQ4 A;  1WG7 A;  1NTV A;  2COA A;  4CYE A;  5DI9 B;  3KY9 A;  3SO6 A;  5C5B A;  5J3T A;  3QIJ A;  1J19 A;  3OAN A;  4KHB B;  3HW2 B;  1V5M A;  2CY4 A;  2IYB A;  4L6E A;  2LYD A;  5GOW B;  5CLL B;  5LOP B;  1EVH A;  2COC A;  3O96 A;  2Z0O A;  5HE2 A;  4HHV A;  3BJI A;  4HDO A;  4K81 A;  2Z0Q A;  4EJN A;  2RGN B;  2QKL A;  1AQC A;  1BY1 A;  2KCJ A;  1ZC4 B;  1GG3 A;  2UZR A;  2E2X A;  2N23 A;  4PNK A;  2CRF A;  3GYO A;  2RVB B;  1FHO A;  2DHJ A;  1TQZ A;  2H7D A;  3ML4 A;  2J0K A;  2UVM A;  3X23 A;  2P0H A;  2D11 A;  3UZT A;  1XKE A;  2L1C A;  2YT0 A;  3TCA A;  3QWM A;  1WI1 A;  3LJU X;  1X86 A;  5FI1 A;  4HAV B;  2DLW A;  2LKO A;  1UNR A;  3QBV B;  2J59 M;  3TO1 A;  1E5W A;  1FHW A;  4NSW A;  1TJ6 A;  4DX9 0;  2MWN B;  2I1J A;  5HE3 A;  1OY2 A;  5DHA B;  3SV1 A;  1P6S A;  1WGU A;  2D9W A;  3TW1 A;  2COF A;  1FGZ A;  1XOD A;  3F0W A;  1AWE A;  1Y19 B;  1ZVR A;  2DYQ A;  3SNH A;  1B55 A;  4GYV A;  5D3V A;  1PLS A;  2M38 A;  2YSZ A;  1KZG A;  2D9X A;  1WJ1 A;  3PP2 A;  5EFX A;  4WJ7 A;  1H10 A;  4A6K A;  4DBB A;  4IAP A;  2RUK B; 
#chains in the Genus database with same CATH topology
 2FJL A;  1SGH A;  3PVL A;  5CLQ B;  1N3H A;  2Z4D A;  3ULC A;  1X11 A;  1MAI A;  2K2J A;  3P7Z A;  4K2O A;  4KHB A;  3FSS A;  2D2Q A;  4ZRJ A;  2J0M A;  5JLJ B;  3A8Q A;  1KZ7 A;  2YS5 A;  4WVF B;  1Z87 A;  1UPQ A;  1QQG A;  1U2B A;  3B77 A;  5LG4 B;  4HDQ A;  4B6H A;  4DIX A;  2DA0 A;  2KUP A;  3AU5 A;  3NSU A;  2I1K A;  3TVV A;  4CHJ A;  2IFS A;  2GCJ A;  3U7D A;  2NZ8 B;  3G9W A;  2ADZ A;  2NMB A;  1W1D A;  4DXA B;  4D0O A;  2M14 A;  2DHI A;  1NU2 A;  4IOY X;  4A6H A;  2ROZ B;  3T06 A;  3ODW A;  4ZRK A;  3WA0 A;  2HE7 A;  4KAX B;  4GPT B;  1Y5O A;  4Z2N A;  1MPH A;  2G35 A;  2HTH B;  2R0D A;  4TYZ A;  3VOQ A;  1M7E A;  4A6F B;  2YS3 A;  5J3Q A;  1V61 A;  1WGQ A;  2GUM A;  3V5W A;  2ELA A;  2OQB A;  1K5G B;  3PZD A;  3PEG A;  2DN6 A;  2YF0 A;  1V5U A;  3A98 B;  4F7H A;  4GN1 A;  3AU4 A;  3U12 A;  1I2H A;  1FB8 A;  3D8E A;  2VRW B;  2Q13 A;  1OQN A;  3HK0 A;  4HB3 B;  2EJ8 A;  5D3Y A;  2DTC A;  3ODO A;  1U29 A;  2P0F A;  2I5F A;  3HQC A;  2GCL A;  4PQ0 A;  2RLO A;  2ELB A;  4H8S A;  1FHX A;  1XX0 A;  4K2P A;  4CSQ A;  4GZU A;  1ISN A;  3KSY A;  2W2W A;  3HIE A;  2RNR B;  2MFQ A;  4HB4 B;  2KR9 A;  1LB1 A;  4A5K A;  3AJ4 A;  4HAU B;  4QXA B;  2AL6 A;  1PFJ A;  4DX8 A;  3ZVR A;  3SUZ A;  1XD4 A;  1EAZ A;  2QKM A;  2NBV A;  4F7U P;  3PG7 A;  2Y8F A;  1V5P A;  5D3X A;  4HB0 B;  4P7I A;  1MIX A;  5D27 A;  1WJM A;  3PVU A;  3ODX A;  4NY0 A;  2KUQ A;  2LG1 A;  4KHA A;  3DCX A;  5KQ1 A;  2H7E A;  3MPX A;  3GF9 A;  3NWA A;  2FJU B;  1KI1 B;  3WYF B;  1U5D A;  2CAY A;  4K17 A;  4YL8 A;  2EMT A;  2D10 A;  1GC6 A;  1UNP A;  2YVC A;  2DX5 A;  2UZS A;  1DYN A;  1P3R A;  3A8P A;  5J3Y A;  1U5E A;  2P8V A;  4HAZ B;  1Q67 A;  5JHG A;  1SHC A;  1U5F A;  4KVG B;  4D6W A;  3IVF A;  2DFK A;  1X1G A;  4GMX B;  2D9V A;  4IFS A;  1DBH A;  2P0D A;  2OTX A;  4WSF A;  4GXB A;  1WVH A;  1V88 A;  4GNK B;  3VIA A;  2ROV A;  5KCV A;  2KR0 A;  2LUL A;  4A6F A;  5DIF B;  1BWN A;  3N7C A;  2ZPY A;  1NTY A;  5DHF B;  3P6A A;  1QC6 A;  4TKN A;  4QJ3 B;  4Z2M B;  3DXC A;  4GMV A;  1FOE A;  5JP4 A;  5C16 A;  1FAO A;  4YON A;  2Z59 A;  1DDM A;  2YT2 A;  4Y94 A;  4MT7 A;  2LOZ A;  4HAW B;  5D3W A;  1UEF A;  2R09 A;  3KZ1 A;  3DXD A;  2EMS A;  3KRX A;  3SYX A;  2VSZ A;  1EGX A;  1ZM0 A;  2Z13 A;  2YT1 A;  3GYP A;  5LON B;  5HE1 A;  1F5X A;  5C5B B;  2DHK A;  3ZDT A;  4MK0 A;  5C79 A;  4HAX B;  1W1G A;  3U8Z A;  3BIN A;  5JHH A;  3HSA A;  4KHO A;  2DYN A;  2AEH A;  5FI0 A;  2R2Y A;  2W2X D;  4XWX A;  3D8F A;  5L81 A;  3M1I B;  2ZKM X;  1RRP B;  2MKR A;  1DRO A;  1ZSQ A;  1EF1 A;  2Y8G A;  2YS1 A;  1M7R A;  1MI1 A;  1UNQ A;  3CXB B;  2Y7B A;  4OT1 A;  5IRS A;  2DKQ A;  5DH9 B;  5C6R A;  4HSI A;  2RRF A;  2K00 A;  4CHM A;  1MK7 B;  1BTN A;  1FGY A;  1U27 A;  2GJY A;  3D8D A;  2L2I A;  1J0W A;  2BCJ A;  1MKE A;  2XQN M;  1NI2 A;  1PMS A;  1DDW A;  2KIG A;  2EC1 A;  2J0J A;  3F5R A;  1V89 A;  2RSG A;  1DDV A;  3ULB A;  1XR0 B;  2YRY A;  3A58 A;  1ZYI A;  1H4R A;  2JP2 A;  1MIZ B;  4ZRI A;  1W1H A;  3TFM A;  1BAK A;  2GS0 A;  3FM8 C;  4HAT B;  4EKU A;  1P5T A;  1BTK A;  2COD A;  3JV3 A;  3PSC A;  1X1F A;  5I2M A;  3CIK A;  4OSN A;  5HE0 A;  1GC7 A;  1XCG A;  1U5G A;  3MDB C;  4HAY B;  4HB2 B;  1K5D B;  1UPR A;  2X18 A;  2DX1 A;  3EO2 A;  3KRW A;  4MY6 A;  3FEH A;  2W2X C;  2VKI A;  3RCP A;  1LW3 A;  2KGX B;  2CY5 A;  4GOU A;  1TXD A;  2N0Y A;  2PZ1 A;  2K2U A;  1OMW A;  2MDX A;  1IRS A;  2D9Y A;  2LOX A;  4D0N B;  1RJ2 A;  4C0A A;  2Z0P A;  2K8E A;  2V76 A;  2I5C A;  3PVW A;  1I7A A;  4EMO A;  4BBK A;  4F7G A;  2K49 A;  2D9Z A;  3NW8 A;  1MK9 B;  2Z14 A;  1ZC3 B;  3DXE A;  2D4Q A;  1X05 A;  2DKP A;  5KQ4 A;  1WG7 A;  1NTV A;  2COA A;  4CYE A;  5DI9 B;  3KY9 A;  3SO6 A;  5C5B A;  5J3T A;  3QIJ A;  1J19 A;  3OAN A;  4KHB B;  3HW2 B;  1V5M A;  2CY4 A;  2IYB A;  5M4Y B;  4L6E A;  2LYD A;  5GOW B;  5I2S A;  5CLL B;  3OHM B;  5LOP B;  1EVH A;  2COC A;  3O96 A;  1T77 A;  2Z0O A;  5HE2 A;  4HHV A;  3BJI A;  4HDO A;  4K81 A;  2Z0Q A;  4EJN A;  2RGN B;  2QKL A;  1AQC A;  1BY1 A;  2KCJ A;  1ZC4 B;  1GG3 A;  2UZR A;  2E2X A;  2N23 A;  4PNK A;  2CRF A;  3GYO A;  2RVB B;  1FHO A;  3NWD A;  2DHJ A;  1TQZ A;  2H7D A;  3ML4 A;  4L1R A;  2J0K A;  2UVM A;  3X23 A;  2P0H A;  2D11 A;  3UZT A;  1XKE A;  2L1C A;  2YT0 A;  3TCA A;  3QWM A;  1WI1 A;  3LJU X;  1X86 A;  5FI1 A;  4HAV B;  2DLW A;  2LKO A;  1UNR A;  3QBV B;  2J59 M;  3NWF A;  4QJ4 B;  3TO1 A;  1E5W A;  1FHW A;  4NSW A;  1TJ6 A;  4DX9 0;  2MWN B;  2I1J A;  5HE3 A;  1OY2 A;  5DHA B;  3SV1 A;  1P6S A;  1WGU A;  2D9W A;  3TW1 A;  2COF A;  1FGZ A;  1XOD A;  3F0W A;  1AWE A;  1Y19 B;  4QJ5 B;  1ZVR A;  2KIE A;  2DYQ A;  3SNH A;  1B55 A;  4GYV A;  5D3V A;  1PLS A;  2M38 A;  2YSZ A;  1KZG A;  2D9X A;  1WJ1 A;  3PP2 A;  5EFX A;  3FVC A;  4WJ7 A;  1H10 A;  4A6K A;  4DBB A;  4IAP A;  2RUK B; 
#chains in the Genus database with same CATH homology
 2FJL A;  1SGH A;  3PVL A;  5CLQ B;  1N3H A;  3ULC A;  1X11 A;  1MAI A;  2K2J A;  3P7Z A;  4K2O A;  3FSS A;  2D2Q A;  4ZRJ A;  2J0M A;  5JLJ B;  3A8Q A;  1KZ7 A;  2YS5 A;  4WVF B;  1Z87 A;  1UPQ A;  1QQG A;  1U2B A;  4HDQ A;  4B6H A;  2DA0 A;  2KUP A;  3AU5 A;  3NSU A;  2I1K A;  3TVV A;  4CHJ A;  2IFS A;  2GCJ A;  3U7D A;  2NZ8 B;  3G9W A;  2ADZ A;  2NMB A;  1W1D A;  4DXA B;  4D0O A;  2M14 A;  2DHI A;  1NU2 A;  4IOY X;  4A6H A;  2ROZ B;  3T06 A;  3ODW A;  4ZRK A;  3WA0 A;  2HE7 A;  4KAX B;  4GPT B;  1Y5O A;  4Z2N A;  1MPH A;  2G35 A;  2HTH B;  2R0D A;  4TYZ A;  3VOQ A;  1M7E A;  4A6F B;  2YS3 A;  5J3Q A;  1V61 A;  1WGQ A;  3V5W A;  2ELA A;  2OQB A;  1K5G B;  3PZD A;  3PEG A;  2DN6 A;  2YF0 A;  1V5U A;  3A98 B;  4F7H A;  4GN1 A;  3AU4 A;  1I2H A;  1FB8 A;  3D8E A;  2VRW B;  2Q13 A;  1OQN A;  3HK0 A;  4HB3 B;  2EJ8 A;  5D3Y A;  2DTC A;  3ODO A;  1U29 A;  2P0F A;  2I5F A;  3HQC A;  2GCL A;  4PQ0 A;  2RLO A;  2ELB A;  4H8S A;  1FHX A;  1XX0 A;  4K2P A;  4GZU A;  1ISN A;  3KSY A;  2W2W A;  2RNR B;  2MFQ A;  4HB4 B;  2KR9 A;  1LB1 A;  4A5K A;  3AJ4 A;  4HAU B;  2AL6 A;  1PFJ A;  4DX8 A;  3ZVR A;  3SUZ A;  1XD4 A;  1EAZ A;  2QKM A;  4F7U P;  3PG7 A;  2Y8F A;  1V5P A;  5D3X A;  4HB0 B;  4P7I A;  1MIX A;  5D27 A;  1WJM A;  3PVU A;  3ODX A;  4NY0 A;  2LG1 A;  4KHA A;  5KQ1 A;  2H7E A;  3MPX A;  3GF9 A;  1KI1 B;  3WYF B;  1U5D A;  2CAY A;  4K17 A;  4YL8 A;  2EMT A;  2D10 A;  1GC6 A;  1UNP A;  2YVC A;  2DX5 A;  2UZS A;  1DYN A;  1P3R A;  3A8P A;  5J3Y A;  1U5E A;  2P8V A;  4HAZ B;  1Q67 A;  5JHG A;  1SHC A;  1U5F A;  4KVG B;  3IVF A;  2DFK A;  1X1G A;  4GMX B;  2D9V A;  4IFS A;  1DBH A;  2P0D A;  2OTX A;  4WSF A;  4GXB A;  1WVH A;  1V88 A;  3VIA A;  2ROV A;  5KCV A;  2LUL A;  4A6F A;  5DIF B;  1BWN A;  3N7C A;  2ZPY A;  1NTY A;  5DHF B;  3P6A A;  1QC6 A;  4TKN A;  4Z2M B;  3DXC A;  4GMV A;  1FOE A;  5JP4 A;  5C16 A;  1FAO A;  4YON A;  1DDM A;  4Y94 A;  4MT7 A;  2LOZ A;  4HAW B;  5D3W A;  1UEF A;  2R09 A;  3KZ1 A;  3DXD A;  2EMS A;  3KRX A;  3SYX A;  2VSZ A;  1EGX A;  1ZM0 A;  2YT1 A;  3GYP A;  5LON B;  5HE1 A;  1F5X A;  5C5B B;  2DHK A;  3ZDT A;  4MK0 A;  5C79 A;  4HAX B;  1W1G A;  3U8Z A;  3BIN A;  5JHH A;  4KHO A;  2DYN A;  2AEH A;  5FI0 A;  2W2X D;  4XWX A;  5L81 A;  3D8F A;  3M1I B;  1RRP B;  2MKR A;  1DRO A;  1ZSQ A;  1EF1 A;  2Y8G A;  2YS1 A;  1M7R A;  1UNQ A;  3CXB B;  2Y7B A;  2DKQ A;  5DH9 B;  5C6R A;  2K00 A;  4CHM A;  1MK7 B;  1BTN A;  1FGY A;  1U27 A;  2GJY A;  3D8D A;  2L2I A;  1J0W A;  2BCJ A;  1MKE A;  2XQN M;  1NI2 A;  1PMS A;  1DDW A;  2EC1 A;  2J0J A;  3F5R A;  1V89 A;  2RSG A;  1DDV A;  3ULB A;  1XR0 B;  2YRY A;  2JP2 A;  1H4R A;  1MIZ B;  4ZRI A;  1W1H A;  3TFM A;  1BAK A;  2GS0 A;  3FM8 C;  4HAT B;  4EKU A;  1P5T A;  1BTK A;  2COD A;  3JV3 A;  3PSC A;  1X1F A;  3CIK A;  5HE0 A;  1GC7 A;  1XCG A;  1U5G A;  3MDB C;  4HAY B;  4HB2 B;  1K5D B;  1UPR A;  2X18 A;  2DX1 A;  3EO2 A;  3KRW A;  4MY6 A;  3FEH A;  2W2X C;  2VKI A;  3RCP A;  1LW3 A;  2KGX B;  2CY5 A;  4GOU A;  1TXD A;  2N0Y A;  2PZ1 A;  2K2U A;  1OMW A;  2MDX A;  1IRS A;  2D9Y A;  2LOX A;  4D0N B;  1RJ2 A;  4C0A A;  2Z0P A;  2V76 A;  2I5C A;  3PVW A;  1I7A A;  4EMO A;  4BBK A;  4F7G A;  2D9Z A;  1MK9 B;  1ZC3 B;  3DXE A;  2D4Q A;  1X05 A;  2DKP A;  5KQ4 A;  1WG7 A;  1NTV A;  2COA A;  4CYE A;  5DI9 B;  3KY9 A;  3SO6 A;  5C5B A;  5J3T A;  3QIJ A;  1J19 A;  3OAN A;  4KHB B;  3HW2 B;  1V5M A;  2CY4 A;  2IYB A;  4L6E A;  2LYD A;  5GOW B;  5CLL B;  5LOP B;  1EVH A;  2COC A;  3O96 A;  2Z0O A;  5HE2 A;  4HHV A;  3BJI A;  4HDO A;  4K81 A;  2Z0Q A;  4EJN A;  2RGN B;  2QKL A;  1AQC A;  1BY1 A;  2KCJ A;  1ZC4 B;  1GG3 A;  2UZR A;  2E2X A;  2N23 A;  4PNK A;  2CRF A;  3GYO A;  2RVB B;  1FHO A;  2DHJ A;  1TQZ A;  2H7D A;  3ML4 A;  2J0K A;  2UVM A;  3X23 A;  2P0H A;  2D11 A;  3UZT A;  1XKE A;  2L1C A;  2YT0 A;  3TCA A;  3QWM A;  1WI1 A;  3LJU X;  1X86 A;  5FI1 A;  4HAV B;  2DLW A;  2LKO A;  1UNR A;  3QBV B;  2J59 M;  3TO1 A;  1E5W A;  1FHW A;  4NSW A;  1TJ6 A;  4DX9 0;  2MWN B;  2I1J A;  5HE3 A;  1OY2 A;  5DHA B;  3SV1 A;  1P6S A;  1WGU A;  2D9W A;  3TW1 A;  2COF A;  1FGZ A;  1XOD A;  3F0W A;  1AWE A;  1Y19 B;  1ZVR A;  2DYQ A;  3SNH A;  1B55 A;  4GYV A;  5D3V A;  1PLS A;  2M38 A;  2YSZ A;  1KZG A;  2D9X A;  1WJ1 A;  3PP2 A;  5EFX A;  4WJ7 A;  1H10 A;  4A6K A;  4DBB A;  4IAP A;  2RUK B;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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5JHGA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations