1XCG | Genus

Total Genus 125

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	125
sequence length	368
structure length	355
Chain Sequence	QNWQHTVGKDVVAGLTQREIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKENLMPREELARLFPNLPELIEIHNSWCEAMKKLREEGPIIKEISDLMLARFDGPAREELQQVAAQFCSYQSIALELIKTKQRKESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLESIIKHTEGGTSEHEKLCRARDQCREILKYVNEAVKQTENRHRLEGYQKRLDATALERASNPLAAEFKSLDLTTRKMIHEGPLTWRISKDKTLDLHVLLLEDLLVLLQKQDEKLLLKCTFSPVLKLNAVLIRSVATDKRAFFIICTSKLGPPQIYELVALTSSDKNTWMELLEEAVRNA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 355 atoms

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355 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Signaling protein activator/signaling protein
source organism	Homo sapiens
publication title	The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle pubmed doi rcsb
molecule keywords	Rho guanine nucleotide exchange factor 11
total genus	125
structure length	355
sequence length	368
chains with identical sequence	E
ec nomenclature
pdb deposition date	2004-09-01

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00621	RhoGEF	RhoGEF domain
A	PF17838	PH_16	PH domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.900.10	Mainly Alpha	Up-down Bundle	Dbl Homology Domain; Chain A	Dbl homology (DH) domain	1xcgA01
2.30.29.30	Mainly Beta	Roll	PH-domain like	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	1xcgA02

4TYZA 3HQCA 2I1JA 1QQGA 2D9ZA 1FB8A 4KHBB 4DX90 1GC6A 1XODA 2R0DA 4GOUA 4ZRJA 3X23A 1AWEA 1MKEA 2W2WA 2CY5A 2NMBA 1U2BA 1OQNA 1MIZB 3UZTA 2DTCA 2COCA 4IAPA 1BTNA 5JLJB 4A5KA 3VIAA 4KHAA 2CAYA 2GCLA 5LONB 4WSFA 1TQZA 2YS3A 5C5BA 1TJ6A 2D9YA 2EMTA 2P8VA 2DYNA 5D27A 5DHFB 4KVGB 4HAYB 2D11A 4NY0A 2ROZB 4B6HA 2DHIA 4ZRKA 1U5FA 4GZUA 5HE2A 3TO1A 3T06A 3FM8C 4PNKA 2M38A 2CODA 2RGNB 3DXDA 2NZ8B 5JHHA 2YRYA 1V5MA 2K2UA 4DXAB 4K2OA 2YSZA 1UPQA 4IOYX 1W1DA 3QIJA 2CRFA 4YONA 2I5CA 2E2XA 4F7UP 1B55A 4HHVA 3KSYA 3KZ1A 2LOXA 1WVHA 2DHKA 3FSSA 4EKUA 1P6SA 1U5GA 4EMOA 2KGXB 3SYXA 1BTKA 5HE1A 1Y19B 1TXDA 2J0JA 2YS1A 3ODWA 4HDQA 5L81A 2W2XD 3QWMA 3A8PA 1GG3A 2V76A 4TKNA 4HB4B 1BAKA 3QBVB 1NTVA 1DDWA 2AL6A 2D2QA 2LG1A 4KAXB 4NSWA 1WJMA 4H8SA 3PSCA 1NTYA 1W1GA 4P7IA 2IYBA 3V5WA 3P7ZA 1KZGA 1XR0B 3TFMA 4BBKA 4CHMA 3KRWA 1OY2A 2L1CA 3VOQA 5DHAB 4HAXB 3F0WA 2ELBA 1EGXA 3TW1A 1EVHA 2EC1A 2RNRB 3NSUA 4F7HA 3F5RA 3LJUX 3BJIA 1P5TA 4GXBA 2DYQA 5HE3A 4MY6A 2LYDA 2YS5A 1KZ7A 1X11A 1PFJA 1SGHA 4A6KA 1P3RA 1DYNA 2D4QA 2YT0A 3D8DA 2P0HA 1LB1A 2Y8FA 3DXCA 3TCAA 5D3XA 4GPTB 1K5GB 2ADZA 1V89A 4YL8A 1IRSA 2VKIA 5HE0A 5KQ4A 2D9VA 2GCJA 3PVWA 3ULBA 5C16A 2Y7BA 5D3VA 3DXEA 1FHXA 3SO6A 4DX8A 2MWNB 1U5EA 4KHOA 1UNPA 1U29A 2Q13A 1MPHA 1V61A 1BY1A 2OQBA 2X18A 4HATB 1DBHA 3M1IB 4HAWB 2H7DA 5C5BB 1XCGA 4HAZB 1H10A 2DX1A 2RSGA 1FGZA 2KUPA 3SUZA 3RCPA 1MIXA 1Y5OA 1MAIA 3HK0A 4K2PA 1RJ2A 2DKQA 1WI1A 1E5WA 3TVVA 3PP2A 4C0AA 3PZDA 2UZRA 3FEHA 5D3YA 2Z0QA 3SNHA 2DX5A 2DHJA 2AEHA 2IFSA 4L6EA 1V5PA 1ZM0A 1EF1A 3OANA 3ML4A 3A8QA 2VRWB 4ZRIA 2DA0A 2Y8GA 3KRXA 2Z0OA 2G35A 4HAUB 1SHCA 2K2JA 2BCJA 4MK0A 1M7EA 3U8ZA 1KI1B 5KCVA 4A6FA 2QKLA 5D3WA 2KCJA 5FI1A 2KR9A 2VSZA 1ZC3B 4CYEA 3GYPA 4WVFB 4A6FB 3ODOA 3PVLA 3PEGA 4K81A 2COAA 3WA0A 3BINA 3MDBC 1X05A 1UNRA 3ODXA 1NU2A 2DN6A 4MT7A 4GMXB 2Z0PA 4HAVB 3O96A 4D0OA 3PG7A 2ZPYA 3ZVRA 1W1HA 1M7RA 1XX0A 3HW2B 1K5DB 2YVCA 1FHWA 3P6AA 3AJ4A 1XKEA 2DKPA 3D8FA 3N7CA 1QC6A 5FI0A 1U27A 4DBBA 2N0YA 1DDMA 5DH9B 2YT1A 1ZVRA 4IFSA 2D9XA 1X86A 5J3QA 1FOEA 4EJNA 1X1FA 3ULCA 2UVMA 1DROA 3G9WA 3WYFB 1WG7A 1EAZA 1XD4A 2OTXA 1H4RA 1RRPB 5DIFB 3AU5A 1NI2A 1FGYA 4Z2MB 1UPRA 4D0NB 2L2IA 4GMVA 3JV3A 5C79A 4PQ0A 1FAOA 1WGUA 2GS0A 5JP4A 2J59M 1F5XA 1ISNA 2ROVA 5J3YA 4XWXA 2DLWA 2M14A 5J3TA 5EFXA 1DDVA 3GF9A 2MDXA 2QKMA 4HDOA 1J0WA 1MK7B 2PZ1A 2HTHB 1J19A 2HE7A 4K17A 1V5UA 5C6RA 2EJ8A 5CLQB 5JHGA 2MFQA 1LW3A 4GN1A 1UEFA 2LOZA 3D8EA 2D9WA 1MK9B 1Q67A 2I1KA 1I2HA 1WGQA 4A6HA 1BWNA 3GYOA 2P0FA 2W2XC 3CIKA 4HB3B 4F7GA 1OMWA 3KY9A 1ZC4B 1Z87A 4HB0B 1FHOA 4HB2B 5LOPB 2R09A 2DFKA 1AQCA 2FJLA 2RVBB 2UZSA 4Z2NA 3EO2A 2ELAA 1V88A 2LULA 1WJ1A 1UNQA 3MPXA 1N3HA 2GJYA 2D10A 5DI9B 2CY4A 5CLLB 5GOWB 2I5FA 3IVFA 2RLOA 2N23A 1U5DA 2YF0A 3CXBB 2XQNM 1I7AA 1X1GA 1PLSA 1PMSA 3U7DA 2MKRA 3SV1A 2K00A 2COFA 3PVUA 2P0DA 2H7EA 5KQ1A 2LKOA 3A98B 3AU4A 3ZDTA 1GC7A 4CHJA 2J0KA 4GYVA 2J0MA 4Y94A 1ZSQA 2RUKB 2EMSA 2JP2A 4WJ7A
chains in the Genus database with same CATH superfamily

4TYZA 3HQCA 3U12A 2I1JA 1QQGA 5I2MA 2D9ZA 1FB8A 4KHBB 4DX90 1GC6A 1XODA 2R0DA 4GOUA 4ZRJA 3X23A 1AWEA 2NMBA 2W2WA 1MKEA 2CY5A 1ZYIA 3A58A 1U2BA 1OQNA 1MIZB 3UZTA 2DTCA 2COCA 4IAPA 1BTNA 4OT1A 5JLJB 4A5KA 3VIAA 4KHAA 2CAYA 2GCLA 5LONB 3HIEA 4WSFA 1TQZA 5I2SA 2YS3A 2KUQA 5C5BA 1TJ6A 2D9YA 2EMTA 2P8VA 2DYNA 5D27A 2Z14A 5DHFB 4KVGB 4HAYB 2D11A 3OHMB 4NY0A 2ROZB 4B6HA 2DHIA 4ZRKA 1U5FA 4GZUA 2FJUB 5HE2A 3TO1A 3T06A 3FM8C 4L1RA 4PNKA 2M38A 2CODA 2RGNB 3DXDA 2NZ8B 5JHHA 2YRYA 1V5MA 2K2UA 4DXAB 4K2OA 2YSZA 1UPQA 4IOYX 1W1DA 3QIJA 2CRFA 4YONA 2I5CA 2E2XA 4F7UP 1B55A 4HHVA 3KSYA 3KZ1A 2LOXA 1WVHA 2DHKA 3FSSA 4EKUA 1P6SA 1U5GA 4EMOA 2KGXB 3SYXA 1BTKA 5HE1A 1Y19B 1TXDA 2J0JA 2YS1A 3ODWA 2K8EA 2R2YA 4HDQA 5L81A 2W2XD 3QWMA 5M4YB 3A8PA 1GG3A 2V76A 2K49A 4TKNA 4HB4B 1BAKA 3QBVB 1NTVA 1DDWA 2AL6A 2D2QA 2LG1A 4KAXB 4NSWA 1WJMA 4H8SA 3PSCA 1NTYA 1W1GA 4P7IA 2IYBA 3V5WA 3P7ZA 1KZGA 1XR0B 3TFMA 4BBKA 4CHMA 3KRWA 1OY2A 2L1CA 3NWAA 5DHAB 3VOQA 4HAXB 3F0WA 2ELBA 1EGXA 2NBVA 1EVHA 3TW1A 2EC1A 2RNRB 3NSUA 4F7HA 3F5RA 3LJUX 3BJIA 1P5TA 4GXBA 2DYQA 5HE3A 2RRFA 4MY6A 2KR0A 2LYDA 2YS5A 1KZ7A 1X11A 1PFJA 1SGHA 4A6KA 1P3RA 1DYNA 2D4QA 2YT0A 2Z59A 3D8DA 2P0HA 1LB1A 2Y8FA 3DXCA 3TCAA 5D3XA 4GPTB 1K5GB 2ADZA 1V89A 4YL8A 1IRSA 2VKIA 5HE0A 5KQ4A 2D9VA 2GCJA 3PVWA 3ULBA 5C16A 2Y7BA 5D3VA 3DXEA 1FHXA 3SO6A 4DX8A 2MWNB 1U5EA 4KHOA 1UNPA 1U29A 2Q13A 1MPHA 1V61A 3DCXA 1BY1A 2OQBA 2X18A 4HATB 1DBHA 3M1IB 4HAWB 2H7DA 5C5BB 1XCGA 4HAZB 1H10A 2DX1A 2RSGA 1FGZA 2KUPA 3SUZA 3RCPA 1MIXA 1Y5OA 3FVCA 1MAIA 3HK0A 4K2PA 1RJ2A 2DKQA 1WI1A 1E5WA 3TVVA 3PP2A 4C0AA 3PZDA 2UZRA 3FEHA 5D3YA 2Z0QA 3SNHA 1T77A 1MI1A 2DX5A 2DHJA 2AEHA 2IFSA 4L6EA 1V5PA 1ZM0A 1EF1A 3OANA 3ML4A 3A8QA 4QXAB 2VRWB 4ZRIA 4D6WA 2DA0A 2Y8GA 3KRXA 2Z0OA 2G35A 4HAUB 1SHCA 2K2JA 2BCJA 4MK0A 3HSAA 1M7EA 3U8ZA 1KI1B 4QJ3B 5KCVA 4A6FA 2QKLA 5D3WA 2KCJA 5FI1A 2KR9A 2VSZA 1ZC3B 4CYEA 3GYPA 4WVFB 4A6FB 3ODOA 3PVLA 3PEGA 4QJ5B 4K81A 2COAA 3WA0A 3BINA 3MDBC 1X05A 1UNRA 3ODXA 1NU2A 2DN6A 4MT7A 4GMXB 2Z0PA 4HAVB 3O96A 4D0OA 3PG7A 2ZPYA 4GNKB 3ZVRA 1W1HA 1M7RA 1XX0A 3HW2B 1K5DB 4CSQA 2YVCA 1FHWA 3P6AA 3AJ4A 1XKEA 2DKPA 3D8FA 3N7CA 1QC6A 5FI0A 5LG4B 1U27A 4DBBA 2N0YA 4DIXA 1DDMA 5DH9B 2YT1A 1ZVRA 3NW8A 4IFSA 2D9XA 1X86A 5J3QA 1FOEA 4EJNA 1X1FA 3ULCA 2UVMA 1DROA 3G9WA 3WYFB 1WG7A 3NWDA 1EAZA 1XD4A 2OTXA 1H4RA 1RRPB 5DIFB 3AU5A 1NI2A 1FGYA 4Z2MB 1UPRA 4D0NB 2L2IA 2ZKMX 4GMVA 3JV3A 3NWFA 5C79A 4PQ0A 1FAOA 1WGUA 2GS0A 5JP4A 2J59M 1F5XA 1ISNA 2ROVA 5J3YA 4XWXA 2DLWA 2M14A 5J3TA 5EFXA 1DDVA 3GF9A 2MDXA 2QKMA 4HDOA 1J0WA 1MK7B 2PZ1A 2HTHB 1J19A 2HE7A 4K17A 1V5UA 5C6RA 2EJ8A 5CLQB 5JHGA 2MFQA 1LW3A 4GN1A 1UEFA 2LOZA 3D8EA 2D9WA 1MK9B 1Q67A 2I1KA 1I2HA 1WGQA 4A6HA 4OSNA 1BWNA 3GYOA 2P0FA 2W2XC 3CIKA 4HB3B 2GUMA 4HSIA 4F7GA 1OMWA 3KY9A 1ZC4B 1Z87A 4HB0B 4QJ4B 1FHOA 4HB2B 5LOPB 2R09A 2DFKA 3B77A 1AQCA 2FJLA 2RVBB 2UZSA 2Z4DA 4Z2NA 3EO2A 2ELAA 1V88A 2LULA 1WJ1A 1UNQA 3MPXA 1N3HA 2GJYA 2D10A 5DI9B 2CY4A 5CLLB 5GOWB 2I5FA 3IVFA 2RLOA 2N23A 1U5DA 2YF0A 2Z13A 3CXBB 2XQNM 1I7AA 1X1GA 1PLSA 1PMSA 3U7DA 2MKRA 2KIEA 3SV1A 2K00A 2COFA 3PVUA 2P0DA 2H7EA 2YT2A 5KQ1A 2LKOA 3A98B 3AU4A 3ZDTA 1GC7A 4CHJA 5IRSA 2J0KA 4GYVA 2KIGA 4KHBA 2J0MA 4Y94A 1ZSQA 2RUKB 2EMSA 2JP2A 4WJ7A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4TYZ A;  3HQC A;  2I1J A;  1QQG A;  2D9Z A;  1FB8 A;  4KHB B;  4DX9 0;  1GC6 A;  1XOD A;  2R0D A;  4GOU A;  4ZRJ A;  3X23 A;  1AWE A;  1MKE A;  2W2W A;  2CY5 A;  2NMB A;  1U2B A;  1OQN A;  1MIZ B;  3UZT A;  2DTC A;  2COC A;  4IAP A;  1BTN A;  5JLJ B;  4A5K A;  3VIA A;  4KHA A;  2CAY A;  2GCL A;  5LON B;  4WSF A;  1TQZ A;  2YS3 A;  5C5B A;  1TJ6 A;  2D9Y A;  2EMT A;  2P8V A;  2DYN A;  5D27 A;  5DHF B;  4KVG B;  4HAY B;  2D11 A;  4NY0 A;  2ROZ B;  4B6H A;  2DHI A;  4ZRK A;  1U5F A;  4GZU A;  5HE2 A;  3TO1 A;  3T06 A;  3FM8 C;  4PNK A;  2M38 A;  2COD A;  2RGN B;  3DXD A;  2NZ8 B;  5JHH A;  2YRY A;  1V5M A;  2K2U A;  4DXA B;  4K2O A;  2YSZ A;  1UPQ A;  4IOY X;  1W1D A;  3QIJ A;  2CRF A;  4YON A;  2I5C A;  2E2X A;  4F7U P;  1B55 A;  4HHV A;  3KSY A;  3KZ1 A;  2LOX A;  1WVH A;  2DHK A;  3FSS A;  4EKU A;  1P6S A;  1U5G A;  4EMO A;  2KGX B;  3SYX A;  1BTK A;  5HE1 A;  1Y19 B;  1TXD A;  2J0J A;  2YS1 A;  3ODW A;  4HDQ A;  5L81 A;  2W2X D;  3QWM A;  3A8P A;  1GG3 A;  2V76 A;  4TKN A;  4HB4 B;  1BAK A;  3QBV B;  1NTV A;  1DDW A;  2AL6 A;  2D2Q A;  2LG1 A;  4KAX B;  4NSW A;  1WJM A;  4H8S A;  3PSC A;  1NTY A;  1W1G A;  4P7I A;  2IYB A;  3V5W A;  3P7Z A;  1KZG A;  1XR0 B;  3TFM A;  4BBK A;  4CHM A;  3KRW A;  1OY2 A;  2L1C A;  3VOQ A;  5DHA B;  4HAX B;  3F0W A;  2ELB A;  1EGX A;  3TW1 A;  1EVH A;  2EC1 A;  2RNR B;  3NSU A;  4F7H A;  3F5R A;  3LJU X;  3BJI A;  1P5T A;  4GXB A;  2DYQ A;  5HE3 A;  4MY6 A;  2LYD A;  2YS5 A;  1KZ7 A;  1X11 A;  1PFJ A;  1SGH A;  4A6K A;  1P3R A;  1DYN A;  2D4Q A;  2YT0 A;  3D8D A;  2P0H A;  1LB1 A;  2Y8F A;  3DXC A;  3TCA A;  5D3X A;  4GPT B;  1K5G B;  2ADZ A;  1V89 A;  4YL8 A;  1IRS A;  2VKI A;  5HE0 A;  5KQ4 A;  2D9V A;  2GCJ A;  3PVW A;  3ULB A;  5C16 A;  2Y7B A;  5D3V A;  3DXE A;  1FHX A;  3SO6 A;  4DX8 A;  2MWN B;  1U5E A;  4KHO A;  1UNP A;  1U29 A;  2Q13 A;  1MPH A;  1V61 A;  1BY1 A;  2OQB A;  2X18 A;  4HAT B;  1DBH A;  3M1I B;  4HAW B;  2H7D A;  5C5B B;  1XCG A;  4HAZ B;  1H10 A;  2DX1 A;  2RSG A;  1FGZ A;  2KUP A;  3SUZ A;  3RCP A;  1MIX A;  1Y5O A;  1MAI A;  3HK0 A;  4K2P A;  1RJ2 A;  2DKQ A;  1WI1 A;  1E5W A;  3TVV A;  3PP2 A;  4C0A A;  3PZD A;  2UZR A;  3FEH A;  5D3Y A;  2Z0Q A;  3SNH A;  2DX5 A;  2DHJ A;  2AEH A;  2IFS A;  4L6E A;  1V5P A;  1ZM0 A;  1EF1 A;  3OAN A;  3ML4 A;  3A8Q A;  2VRW B;  4ZRI A;  2DA0 A;  2Y8G A;  3KRX A;  2Z0O A;  2G35 A;  4HAU B;  1SHC A;  2K2J A;  2BCJ A;  4MK0 A;  1M7E A;  3U8Z A;  1KI1 B;  5KCV A;  4A6F A;  2QKL A;  5D3W A;  2KCJ A;  5FI1 A;  2KR9 A;  2VSZ A;  1ZC3 B;  4CYE A;  3GYP A;  4WVF B;  4A6F B;  3ODO A;  3PVL A;  3PEG A;  4K81 A;  2COA A;  3WA0 A;  3BIN A;  3MDB C;  1X05 A;  1UNR A;  3ODX A;  1NU2 A;  2DN6 A;  4MT7 A;  4GMX B;  2Z0P A;  4HAV B;  3O96 A;  4D0O A;  3PG7 A;  2ZPY A;  3ZVR A;  1W1H A;  1M7R A;  1XX0 A;  3HW2 B;  1K5D B;  2YVC A;  1FHW A;  3P6A A;  3AJ4 A;  1XKE A;  2DKP A;  3D8F A;  3N7C A;  1QC6 A;  5FI0 A;  1U27 A;  4DBB A;  2N0Y A;  1DDM A;  5DH9 B;  2YT1 A;  1ZVR A;  4IFS A;  2D9X A;  1X86 A;  5J3Q A;  1FOE A;  4EJN A;  1X1F A;  3ULC A;  2UVM A;  1DRO A;  3G9W A;  3WYF B;  1WG7 A;  1EAZ A;  1XD4 A;  2OTX A;  1H4R A;  1RRP B;  5DIF B;  3AU5 A;  1NI2 A;  1FGY A;  4Z2M B;  1UPR A;  4D0N B;  2L2I A;  4GMV A;  3JV3 A;  5C79 A;  4PQ0 A;  1FAO A;  1WGU A;  2GS0 A;  5JP4 A;  2J59 M;  1F5X A;  1ISN A;  2ROV A;  5J3Y A;  4XWX A;  2DLW A;  2M14 A;  5J3T A;  5EFX A;  1DDV A;  3GF9 A;  2MDX A;  2QKM A;  4HDO A;  1J0W A;  1MK7 B;  2PZ1 A;  2HTH B;  1J19 A;  2HE7 A;  4K17 A;  1V5U A;  5C6R A;  2EJ8 A;  5CLQ B;  5JHG A;  2MFQ A;  1LW3 A;  4GN1 A;  1UEF A;  2LOZ A;  3D8E A;  2D9W A;  1MK9 B;  1Q67 A;  2I1K A;  1I2H A;  1WGQ A;  4A6H A;  1BWN A;  3GYO A;  2P0F A;  2W2X C;  3CIK A;  4HB3 B;  4F7G A;  1OMW A;  3KY9 A;  1ZC4 B;  1Z87 A;  4HB0 B;  1FHO A;  4HB2 B;  5LOP B;  2R09 A;  2DFK A;  1AQC A;  2FJL A;  2RVB B;  2UZS A;  4Z2N A;  3EO2 A;  2ELA A;  1V88 A;  2LUL A;  1WJ1 A;  1UNQ A;  3MPX A;  1N3H A;  2GJY A;  2D10 A;  5DI9 B;  2CY4 A;  5CLL B;  5GOW B;  2I5F A;  3IVF A;  2RLO A;  2N23 A;  1U5D A;  2YF0 A;  3CXB B;  2XQN M;  1I7A A;  1X1G A;  1PLS A;  1PMS A;  3U7D A;  2MKR A;  3SV1 A;  2K00 A;  2COF A;  3PVU A;  2P0D A;  2H7E A;  5KQ1 A;  2LKO A;  3A98 B;  3AU4 A;  3ZDT A;  1GC7 A;  4CHJ A;  2J0K A;  4GYV A;  2J0M A;  4Y94 A;  1ZSQ A;  2RUK B;  2EMS A;  2JP2 A;  4WJ7 A; 
#chains in the Genus database with same CATH topology
 4TYZ A;  3HQC A;  3U12 A;  2I1J A;  1QQG A;  5I2M A;  2D9Z A;  1FB8 A;  4KHB B;  4DX9 0;  1GC6 A;  1XOD A;  2R0D A;  4GOU A;  4ZRJ A;  3X23 A;  1AWE A;  2NMB A;  2W2W A;  1MKE A;  2CY5 A;  1ZYI A;  3A58 A;  1U2B A;  1OQN A;  1MIZ B;  3UZT A;  2DTC A;  2COC A;  4IAP A;  1BTN A;  4OT1 A;  5JLJ B;  4A5K A;  3VIA A;  4KHA A;  2CAY A;  2GCL A;  5LON B;  3HIE A;  4WSF A;  1TQZ A;  5I2S A;  2YS3 A;  2KUQ A;  5C5B A;  1TJ6 A;  2D9Y A;  2EMT A;  2P8V A;  2DYN A;  5D27 A;  2Z14 A;  5DHF B;  4KVG B;  4HAY B;  2D11 A;  3OHM B;  4NY0 A;  2ROZ B;  4B6H A;  2DHI A;  4ZRK A;  1U5F A;  4GZU A;  2FJU B;  5HE2 A;  3TO1 A;  3T06 A;  3FM8 C;  4L1R A;  4PNK A;  2M38 A;  2COD A;  2RGN B;  3DXD A;  2NZ8 B;  5JHH A;  2YRY A;  1V5M A;  2K2U A;  4DXA B;  4K2O A;  2YSZ A;  1UPQ A;  4IOY X;  1W1D A;  3QIJ A;  2CRF A;  4YON A;  2I5C A;  2E2X A;  4F7U P;  1B55 A;  4HHV A;  3KSY A;  3KZ1 A;  2LOX A;  1WVH A;  2DHK A;  3FSS A;  4EKU A;  1P6S A;  1U5G A;  4EMO A;  2KGX B;  3SYX A;  1BTK A;  5HE1 A;  1Y19 B;  1TXD A;  2J0J A;  2YS1 A;  3ODW A;  2K8E A;  2R2Y A;  4HDQ A;  5L81 A;  2W2X D;  3QWM A;  5M4Y B;  3A8P A;  1GG3 A;  2V76 A;  2K49 A;  4TKN A;  4HB4 B;  1BAK A;  3QBV B;  1NTV A;  1DDW A;  2AL6 A;  2D2Q A;  2LG1 A;  4KAX B;  4NSW A;  1WJM A;  4H8S A;  3PSC A;  1NTY A;  1W1G A;  4P7I A;  2IYB A;  3V5W A;  3P7Z A;  1KZG A;  1XR0 B;  3TFM A;  4BBK A;  4CHM A;  3KRW A;  1OY2 A;  2L1C A;  3NWA A;  5DHA B;  3VOQ A;  4HAX B;  3F0W A;  2ELB A;  1EGX A;  2NBV A;  1EVH A;  3TW1 A;  2EC1 A;  2RNR B;  3NSU A;  4F7H A;  3F5R A;  3LJU X;  3BJI A;  1P5T A;  4GXB A;  2DYQ A;  5HE3 A;  2RRF A;  4MY6 A;  2KR0 A;  2LYD A;  2YS5 A;  1KZ7 A;  1X11 A;  1PFJ A;  1SGH A;  4A6K A;  1P3R A;  1DYN A;  2D4Q A;  2YT0 A;  2Z59 A;  3D8D A;  2P0H A;  1LB1 A;  2Y8F A;  3DXC A;  3TCA A;  5D3X A;  4GPT B;  1K5G B;  2ADZ A;  1V89 A;  4YL8 A;  1IRS A;  2VKI A;  5HE0 A;  5KQ4 A;  2D9V A;  2GCJ A;  3PVW A;  3ULB A;  5C16 A;  2Y7B A;  5D3V A;  3DXE A;  1FHX A;  3SO6 A;  4DX8 A;  2MWN B;  1U5E A;  4KHO A;  1UNP A;  1U29 A;  2Q13 A;  1MPH A;  1V61 A;  3DCX A;  1BY1 A;  2OQB A;  2X18 A;  4HAT B;  1DBH A;  3M1I B;  4HAW B;  2H7D A;  5C5B B;  1XCG A;  4HAZ B;  1H10 A;  2DX1 A;  2RSG A;  1FGZ A;  2KUP A;  3SUZ A;  3RCP A;  1MIX A;  1Y5O A;  3FVC A;  1MAI A;  3HK0 A;  4K2P A;  1RJ2 A;  2DKQ A;  1WI1 A;  1E5W A;  3TVV A;  3PP2 A;  4C0A A;  3PZD A;  2UZR A;  3FEH A;  5D3Y A;  2Z0Q A;  3SNH A;  1T77 A;  1MI1 A;  2DX5 A;  2DHJ A;  2AEH A;  2IFS A;  4L6E A;  1V5P A;  1ZM0 A;  1EF1 A;  3OAN A;  3ML4 A;  3A8Q A;  4QXA B;  2VRW B;  4ZRI A;  4D6W A;  2DA0 A;  2Y8G A;  3KRX A;  2Z0O A;  2G35 A;  4HAU B;  1SHC A;  2K2J A;  2BCJ A;  4MK0 A;  3HSA A;  1M7E A;  3U8Z A;  1KI1 B;  4QJ3 B;  5KCV A;  4A6F A;  2QKL A;  5D3W A;  2KCJ A;  5FI1 A;  2KR9 A;  2VSZ A;  1ZC3 B;  4CYE A;  3GYP A;  4WVF B;  4A6F B;  3ODO A;  3PVL A;  3PEG A;  4QJ5 B;  4K81 A;  2COA A;  3WA0 A;  3BIN A;  3MDB C;  1X05 A;  1UNR A;  3ODX A;  1NU2 A;  2DN6 A;  4MT7 A;  4GMX B;  2Z0P A;  4HAV B;  3O96 A;  4D0O A;  3PG7 A;  2ZPY A;  4GNK B;  3ZVR A;  1W1H A;  1M7R A;  1XX0 A;  3HW2 B;  1K5D B;  4CSQ A;  2YVC A;  1FHW A;  3P6A A;  3AJ4 A;  1XKE A;  2DKP A;  3D8F A;  3N7C A;  1QC6 A;  5FI0 A;  5LG4 B;  1U27 A;  4DBB A;  2N0Y A;  4DIX A;  1DDM A;  5DH9 B;  2YT1 A;  1ZVR A;  3NW8 A;  4IFS A;  2D9X A;  1X86 A;  5J3Q A;  1FOE A;  4EJN A;  1X1F A;  3ULC A;  2UVM A;  1DRO A;  3G9W A;  3WYF B;  1WG7 A;  3NWD A;  1EAZ A;  1XD4 A;  2OTX A;  1H4R A;  1RRP B;  5DIF B;  3AU5 A;  1NI2 A;  1FGY A;  4Z2M B;  1UPR A;  4D0N B;  2L2I A;  2ZKM X;  4GMV A;  3JV3 A;  3NWF A;  5C79 A;  4PQ0 A;  1FAO A;  1WGU A;  2GS0 A;  5JP4 A;  2J59 M;  1F5X A;  1ISN A;  2ROV A;  5J3Y A;  4XWX A;  2DLW A;  2M14 A;  5J3T A;  5EFX A;  1DDV A;  3GF9 A;  2MDX A;  2QKM A;  4HDO A;  1J0W A;  1MK7 B;  2PZ1 A;  2HTH B;  1J19 A;  2HE7 A;  4K17 A;  1V5U A;  5C6R A;  2EJ8 A;  5CLQ B;  5JHG A;  2MFQ A;  1LW3 A;  4GN1 A;  1UEF A;  2LOZ A;  3D8E A;  2D9W A;  1MK9 B;  1Q67 A;  2I1K A;  1I2H A;  1WGQ A;  4A6H A;  4OSN A;  1BWN A;  3GYO A;  2P0F A;  2W2X C;  3CIK A;  4HB3 B;  2GUM A;  4HSI A;  4F7G A;  1OMW A;  3KY9 A;  1ZC4 B;  1Z87 A;  4HB0 B;  4QJ4 B;  1FHO A;  4HB2 B;  5LOP B;  2R09 A;  2DFK A;  3B77 A;  1AQC A;  2FJL A;  2RVB B;  2UZS A;  2Z4D A;  4Z2N A;  3EO2 A;  2ELA A;  1V88 A;  2LUL A;  1WJ1 A;  1UNQ A;  3MPX A;  1N3H A;  2GJY A;  2D10 A;  5DI9 B;  2CY4 A;  5CLL B;  5GOW B;  2I5F A;  3IVF A;  2RLO A;  2N23 A;  1U5D A;  2YF0 A;  2Z13 A;  3CXB B;  2XQN M;  1I7A A;  1X1G A;  1PLS A;  1PMS A;  3U7D A;  2MKR A;  2KIE A;  3SV1 A;  2K00 A;  2COF A;  3PVU A;  2P0D A;  2H7E A;  2YT2 A;  5KQ1 A;  2LKO A;  3A98 B;  3AU4 A;  3ZDT A;  1GC7 A;  4CHJ A;  5IRS A;  2J0K A;  4GYV A;  2KIG A;  4KHB A;  2J0M A;  4Y94 A;  1ZSQ A;  2RUK B;  2EMS A;  2JP2 A;  4WJ7 A; 
#chains in the Genus database with same CATH homology
 4TYZ A;  3HQC A;  2I1J A;  1QQG A;  2D9Z A;  1FB8 A;  4KHB B;  4DX9 0;  1GC6 A;  1XOD A;  2R0D A;  4GOU A;  4ZRJ A;  3X23 A;  1AWE A;  1MKE A;  2W2W A;  2CY5 A;  2NMB A;  1U2B A;  1OQN A;  1MIZ B;  3UZT A;  2DTC A;  2COC A;  4IAP A;  1BTN A;  5JLJ B;  4A5K A;  3VIA A;  4KHA A;  2CAY A;  2GCL A;  5LON B;  4WSF A;  1TQZ A;  2YS3 A;  5C5B A;  1TJ6 A;  2D9Y A;  2EMT A;  2P8V A;  2DYN A;  5D27 A;  5DHF B;  4KVG B;  4HAY B;  2D11 A;  4NY0 A;  2ROZ B;  4B6H A;  2DHI A;  4ZRK A;  1U5F A;  4GZU A;  5HE2 A;  3TO1 A;  3T06 A;  3FM8 C;  4PNK A;  2M38 A;  2COD A;  2RGN B;  3DXD A;  2NZ8 B;  5JHH A;  2YRY A;  1V5M A;  2K2U A;  4DXA B;  4K2O A;  2YSZ A;  1UPQ A;  4IOY X;  1W1D A;  3QIJ A;  2CRF A;  4YON A;  2I5C A;  2E2X A;  4F7U P;  1B55 A;  4HHV A;  3KSY A;  3KZ1 A;  2LOX A;  1WVH A;  2DHK A;  3FSS A;  4EKU A;  1P6S A;  1U5G A;  4EMO A;  2KGX B;  3SYX A;  1BTK A;  5HE1 A;  1Y19 B;  1TXD A;  2J0J A;  2YS1 A;  3ODW A;  4HDQ A;  5L81 A;  2W2X D;  3QWM A;  3A8P A;  1GG3 A;  2V76 A;  4TKN A;  4HB4 B;  1BAK A;  3QBV B;  1NTV A;  1DDW A;  2AL6 A;  2D2Q A;  2LG1 A;  4KAX B;  4NSW A;  1WJM A;  4H8S A;  3PSC A;  1NTY A;  1W1G A;  4P7I A;  2IYB A;  3V5W A;  3P7Z A;  1KZG A;  1XR0 B;  3TFM A;  4BBK A;  4CHM A;  3KRW A;  1OY2 A;  2L1C A;  3VOQ A;  5DHA B;  4HAX B;  3F0W A;  2ELB A;  1EGX A;  3TW1 A;  1EVH A;  2EC1 A;  2RNR B;  3NSU A;  4F7H A;  3F5R A;  3LJU X;  3BJI A;  1P5T A;  4GXB A;  2DYQ A;  5HE3 A;  4MY6 A;  2LYD A;  2YS5 A;  1KZ7 A;  1X11 A;  1PFJ A;  1SGH A;  4A6K A;  1P3R A;  1DYN A;  2D4Q A;  2YT0 A;  3D8D A;  2P0H A;  1LB1 A;  2Y8F A;  3DXC A;  3TCA A;  5D3X A;  4GPT B;  1K5G B;  2ADZ A;  1V89 A;  4YL8 A;  1IRS A;  2VKI A;  5HE0 A;  5KQ4 A;  2D9V A;  2GCJ A;  3PVW A;  3ULB A;  5C16 A;  2Y7B A;  5D3V A;  3DXE A;  1FHX A;  3SO6 A;  4DX8 A;  2MWN B;  1U5E A;  4KHO A;  1UNP A;  1U29 A;  2Q13 A;  1MPH A;  1V61 A;  1BY1 A;  2OQB A;  2X18 A;  4HAT B;  1DBH A;  3M1I B;  4HAW B;  2H7D A;  5C5B B;  1XCG A;  4HAZ B;  1H10 A;  2DX1 A;  2RSG A;  1FGZ A;  2KUP A;  3SUZ A;  3RCP A;  1MIX A;  1Y5O A;  1MAI A;  3HK0 A;  4K2P A;  1RJ2 A;  2DKQ A;  1WI1 A;  1E5W A;  3TVV A;  3PP2 A;  4C0A A;  3PZD A;  2UZR A;  3FEH A;  5D3Y A;  2Z0Q A;  3SNH A;  2DX5 A;  2DHJ A;  2AEH A;  2IFS A;  4L6E A;  1V5P A;  1ZM0 A;  1EF1 A;  3OAN A;  3ML4 A;  3A8Q A;  2VRW B;  4ZRI A;  2DA0 A;  2Y8G A;  3KRX A;  2Z0O A;  2G35 A;  4HAU B;  1SHC A;  2K2J A;  2BCJ A;  4MK0 A;  1M7E A;  3U8Z A;  1KI1 B;  5KCV A;  4A6F A;  2QKL A;  5D3W A;  2KCJ A;  5FI1 A;  2KR9 A;  2VSZ A;  1ZC3 B;  4CYE A;  3GYP A;  4WVF B;  4A6F B;  3ODO A;  3PVL A;  3PEG A;  4K81 A;  2COA A;  3WA0 A;  3BIN A;  3MDB C;  1X05 A;  1UNR A;  3ODX A;  1NU2 A;  2DN6 A;  4MT7 A;  4GMX B;  2Z0P A;  4HAV B;  3O96 A;  4D0O A;  3PG7 A;  2ZPY A;  3ZVR A;  1W1H A;  1M7R A;  1XX0 A;  3HW2 B;  1K5D B;  2YVC A;  1FHW A;  3P6A A;  3AJ4 A;  1XKE A;  2DKP A;  3D8F A;  3N7C A;  1QC6 A;  5FI0 A;  1U27 A;  4DBB A;  2N0Y A;  1DDM A;  5DH9 B;  2YT1 A;  1ZVR A;  4IFS A;  2D9X A;  1X86 A;  5J3Q A;  1FOE A;  4EJN A;  1X1F A;  3ULC A;  2UVM A;  1DRO A;  3G9W A;  3WYF B;  1WG7 A;  1EAZ A;  1XD4 A;  2OTX A;  1H4R A;  1RRP B;  5DIF B;  3AU5 A;  1NI2 A;  1FGY A;  4Z2M B;  1UPR A;  4D0N B;  2L2I A;  4GMV A;  3JV3 A;  5C79 A;  4PQ0 A;  1FAO A;  1WGU A;  2GS0 A;  5JP4 A;  2J59 M;  1F5X A;  1ISN A;  2ROV A;  5J3Y A;  4XWX A;  2DLW A;  2M14 A;  5J3T A;  5EFX A;  1DDV A;  3GF9 A;  2MDX A;  2QKM A;  4HDO A;  1J0W A;  1MK7 B;  2PZ1 A;  2HTH B;  1J19 A;  2HE7 A;  4K17 A;  1V5U A;  5C6R A;  2EJ8 A;  5CLQ B;  5JHG A;  2MFQ A;  1LW3 A;  4GN1 A;  1UEF A;  2LOZ A;  3D8E A;  2D9W A;  1MK9 B;  1Q67 A;  2I1K A;  1I2H A;  1WGQ A;  4A6H A;  1BWN A;  3GYO A;  2P0F A;  2W2X C;  3CIK A;  4HB3 B;  4F7G A;  1OMW A;  3KY9 A;  1ZC4 B;  1Z87 A;  4HB0 B;  1FHO A;  4HB2 B;  5LOP B;  2R09 A;  2DFK A;  1AQC A;  2FJL A;  2RVB B;  2UZS A;  4Z2N A;  3EO2 A;  2ELA A;  1V88 A;  2LUL A;  1WJ1 A;  1UNQ A;  3MPX A;  1N3H A;  2GJY A;  2D10 A;  5DI9 B;  2CY4 A;  5CLL B;  5GOW B;  2I5F A;  3IVF A;  2RLO A;  2N23 A;  1U5D A;  2YF0 A;  3CXB B;  2XQN M;  1I7A A;  1X1G A;  1PLS A;  1PMS A;  3U7D A;  2MKR A;  3SV1 A;  2K00 A;  2COF A;  3PVU A;  2P0D A;  2H7E A;  5KQ1 A;  2LKO A;  3A98 B;  3AU4 A;  3ZDT A;  1GC7 A;  4CHJ A;  2J0K A;  4GYV A;  2J0M A;  4Y94 A;  1ZSQ A;  2RUK B;  2EMS A;  2JP2 A;  4WJ7 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1XCGA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations