The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
16
|
sequence length |
100
|
structure length |
96
|
Chain Sequence |
QECTKFKVSSCRECIESGPGCTWCQKLNFTGPGDPDSIRCDTRPQLLMRGCAADDIMDPTSLAETQEDQKQLSPQKVTLYLRPGQAAAFNVTFRRA
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
A structural hypothesis for the transition between bent and extended conformations of the leukocyte beta2 integrins
pubmed doi rcsb |
| molecule keywords |
Integrin beta-2
|
| molecule tags |
Cell adhesion
|
| source organism |
Homo sapiens
|
| total genus |
16
|
| structure length |
96
|
| sequence length |
100
|
| ec nomenclature | |
| pdb deposition date | 2007-03-07 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF17205 | PSI_integrin | Integrin plexin domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Single Sheet | N-terminal domain of TfIIb | N-terminal domain of TfIIb | ||
| Alpha Beta | 2-Layer Sandwich | ligand-binding face of the semaphorins, domain 2 | ligand-binding face of the semaphorins, domain 2 |
#chains in the Genus database with same CATH superfamily 4WK2 B; 2P28 A; 3NIF B; 3AFC A; 3T3P B; 1SSL A; 3ZE1 B; 4UM9 B; 3ZE0 B; 2VDL B; 3AL8 B; 1U8C B; 4O3T B; 3VI4 B; 1YUK A; 1OLZ A; 2VDN B; 3OKW A; 4UM8 B; 2UZY B; 2VDQ B; 4GZ8 A; 4UM9 D; 3NIG B; 4K3J B; 3NID B; 4WJK B; 3ZDX B; 3OL2 B; 5E6S B; 5E6R B; 5E6U B; 2P26 A; 2VDO B; 3ZE2 B; 4Z7O B; 3ZDY B; 4Z7Q B; 3AL9 A; 4Z7N B; 2VDP B; 3AL8 A; 4WK0 B; 3T3M B; 4FWW A; 2VDM B; 5HDB B; 3ZDZ B; 2VC2 B; 4WK4 B; 2VDK B; 3NVQ A; 1TYE B; 3OL2 A; 1SHY B; 2VDR B; 3VI3 B; 3FCU B; 3OKY B; 4O3U B; #chains in the Genus database with same CATH topology 1K9M 1; 1VQ5 Z; 1M1K 2; 1SIW A; 3NH8 A; 3OW2 Y; 4NBG A; 1Q16 A; 1QYP A; 1WZN A; 3CCV Z; 3CC2 1; 2YU9 I; 1YIJ Z; 4QTU A; 3CD6 1; 3CCJ Z; 1Q7Y 1; 2VUM I; 2PM9 A; 2V45 A; 3S15 I; 1VQN 1; 5C44 I; 3J7A 4; 3QWU A; 4DK1 A; 2JNY A; 3S1Q I; 4A3G I; 3GTK I; 1YI2 1; 1RO2 A; 2QRC B; 2H85 A; 1QF8 A; 1Y1V S; 1YHQ 1; 2JUB A; 4E2W A; 2R7Z I; 4RVD A; 1L1O C; 2GTH A; 3IF8 A; 2JIP A; 2AYD A; 1RO4 A; 2IZ4 A; 3EER A; 2QR1 B; 3H0G I; 5FLM I; 1Q81 1; 2VDR B; 2VF1 A; 5IT9 b; 2QKD A; 4A3J I; 1TWC I; 3PO3 S; 3IFU A; 5IT9 f; 1VQ4 Z; 3RZO I; 1YIJ 1; 2Y0S A; 3CCJ 1; 2JS4 A; 1RO0 A; 2JIO A; 4WJK B; 5D1P A; 2BJO A; 2QA4 Z; 3CCU Z; 4A3B I; 4RVG A; 4A3D I; 5LL6 f; 3G71 1; 3D2L A; 3CPW Y; 1KRL A; 4XX2 A; 2JIQ A; 1Q86 1; 1DL6 A; 3D6W A; 4MON A; 3T3P B; 1Y8C A; 5C4J I; 3I55 Z; 4UM9 B; 1FDO A; 1OLZ A; 3CCL 1; 4E31 A; 2RBL A; 2E9H A; 1KC8 1; 4BY7 I; 1ML8 A; 3CCE Z; 3CQZ I; 3ZE2 B; 4MD8 A; 3J81 b; 4A3M I; 4Z7N B; 4RVH A; 1S7M A; 5IP9 I; 1I6H I; 1TYE B; 2E7Z A; 1VQO Z; 1VQN Z; 1VQ4 1; 1PFT A; 1QXF A; 3GCF A; 4WK2 B; 1X3W A; 4MD9 A; 1M1K 1; 4NBC A; 1QVF Y; 1VQM Z; 3ZE1 B; 4MD7 A; 1W2B Z; 1YI2 Z; 1RQF A; 2PK7 A; 2QA4 1; 2JIR A; 1JJ2 Z; 3S14 I; 3CC7 Z; 2VPY A; 3NH4 A; 2DE7 A; 4E30 A; 5FLX b; 3Q87 A; 4EWC A; 2JWG A; 2RT9 A; 2JR6 A; 5FLX f; 4AYB A; 5A2Q b; 2G2K A; 4E33 A; 5A2Q f; 2OOX B; 2DE5 A; 3MZK B; 2R6M A; 1YUA A; 4E2Y A; 4E32 A; 2VDN B; 3VI4 B; 3CCE 1; 1TWG I; 4DQY B; 4HGZ A; 4BBS I; 2IZ3 A; 1ZB8 A; 1YJ9 1; 3CXC Z; 3ZDY B; 2F4M A; 2JMO A; 3AL8 A; 3T3M B; 1VQO 1; 1LQL A; 3HOU I; 3S2D I; 2DE6 A; 5T67 A; 4S1T A; 3J80 f; 4X6A I; 1WW9 A; 1ZB9 A; 3G71 Z; 1VQM 1; 3I56 1; 2I3C A; 3G6E Z; 3CC7 1; 1U8C B; 2V3V A; 3S1N I; 3HOW I; 3NIG B; 1YJW Z; 4A3K I; 4NOZ A; 3CCL Z; 2VDO B; 3NFZ A; 4NB8 A; 2QLV B; 3NDJ A; 4A3I I; 1S72 Z; 3KIF A; 2QEX 1; 1VQ6 Z; 2EGT A; 3OL2 A; 3M4O I; 2JA6 I; 4RS4 A; 3G4S Z; 2HF1 A; 2OTL 1; 1RLY A; 4QTT A; 3T4N B; 2V8K A; 3ESW A; 3HOV I; 2VPZ A; 2QRE B; 4K3J B; 3CCQ Z; 1FDI A; 2VPW A; 4Z7Q B; 1QVG Z; 3CC4 Z; 2VPX A; 2V8J A; 1VQL Z; 4A3C I; 1N8R 2; 2NVT I; 3GTP I; 2LEX A; 3G6E 1; 3HOX I; 4NFR A; 1Z02 A; 1YJW 1; 3CCM Z; 4Y52 I; 2UZY B; 2NVX I; 4NBE A; 3D9X A; 1S72 1; 3F3P C; 3VMH A; 1W2B Y; 1VQ6 1; 3JAM b; 1AA6 A; 4A3F I; 3G4S 1; 1K83 I; 1USP A; 1YJ9 Z; 1JJ2 Y; 3S1M I; 3JAM f; 3M3Y I; 2LFU A; 2AKL A; 1N2F A; 1X0T A; 3VMI A; 5C3E I; 2M48 A; 1NUI A; 1TFI A; 3BG0 B; 3NDI A; 3GTM I; 2LIY A; 3I56 Z; 3CCQ 1; 1K8A 2; 1K73 2; 4O3T B; 3OKW A; 2K3R A; 3EED A; 2NVQ I; 4UM9 D; 4A3L I; 4RV9 A; 3CC4 1; 4Z7O B; 2NVY I; 1WCM I; 1VQL 1; 3CCR Z; 2VUG A; 1Q82 2; 4NBB A; 1KQS Z; 3ZDZ B; 2VC2 B; 1KD1 1; 1SHY B; 2QRD B; 3CXC Y; 2QEX Z; 3CCM 1; 1M90 2; 4A3E I; 4NB9 A; 3S1R I; 2Q4Z A; 3AL8 B; 4Y7N I; 3FKI I; 1TWH I; 3GTQ I; 3S16 I; 2OTL Z; 4A93 I; 3FQM A; 4MRI A; 3F3F C; 2JIM A; 2V8I A; 1R9T I; 4RVF A; 1Y1V I; 3I07 A; 1VQ9 Z; 3TDH B; 3LUS A; 2B63 I; 1NJI 2; 2O53 A; 3J80 b; 2OZK A; 4HH4 A; 1KD1 2; 2W03 A; 3VI3 B; 3OKY B; 3P5J B; 3VB9 A; 3CCS Z; 4CL1 A; 1Z01 A; 2WB1 A; 1X3Z A; 4TNU A; 3GTJ I; 3CME Z; 1WII A; 1TWF I; 1VLA A; 3FQQ A; 3K7A I; 4BXX I; 4UM8 B; 2VDQ B; 4MXU A; 3PO3 I; 3HOZ I; 3OL2 B; 3PO2 I; 2IV2 X; 3CCR 1; 3GKQ A; 5E6U B; 2P26 A; 3H3V J; 1YIT 1; 3OW2 Z; 2OTJ Z; 3NVQ A; 1N8R 1; 1VQ7 1; 4DGL A; 3FCU B; 1K9M 2; 4E2Z A; 1QVG Y; 1VQP Z; 2RHB A; 1RNI A; 1YJN 1; 3KIH A; 1WJ2 A; 2VDL B; 3MON A; 1I3Q I; 2J6A A; 1YUK A; 1ZH1 A; 3IX0 A; 4GZ8 A; 1NP6 A; 1VQ9 1; 3ZDX B; 5E6S B; 1Q7Y 2; 3I4N I; 2GU2 A; 4NBD A; 1VQK Z; 2VDP B; 4BY1 I; 4FWW A; 3HKZ A; 3BG1 B; 1VQ5 1; 2RPR A; 5D1O B; 2E2J I; 3CCS 1; 2JA7 I; 3CCV 1; 2P28 A; 3CME 1; 3NIF B; 4BBR I; 1SSL A; 5AN9 F; 1TWA I; 3U50 C; 1K8A 1; 2WAQ A; 1K73 1; 1USP B; 5D1O A; 3I4M I; 3NID B; 3GTO I; 2R93 I; 1VQ8 Z; 3MZL B; 1SFO I; 1Y1W I; 2Q51 A; 3AL9 A; 2OTJ 1; 2F4O A; 2M6N A; 1Q82 1; 5IP7 I; 2JA8 I; 5HDB B; 4WK4 B; 4NBH A; 2ZAE B; 2K5R A; 1Q81 2; 3GTL I; 2GTI A; 3CMA Z; 1VQP 1; 2RIQ A; 2KI7 B; 3AFC A; 5CM2 M; 1M90 1; 3S17 I; 3HOY I; 3ZE0 B; 2W04 A; 1KQS Y; 2OOY B; 2P3Y A; 4MH4 A; 3VTN A; 3CPW Z; 1I50 I; 3CC2 Z; 4E2X A; 1VQK 1; 3S2H I; 3RZD I; 3CD6 Z; 4WK0 B; 3J81 f; 1NJI 1; 2VDK B; 1YIT Z; 5T6B A; 1Q86 2; 4NH1 C; 3VMG A; 4O3U B; 2JWH A; 4NBF A; 1VQ7 Z; 3GTG I; 3NH5 A; 2E2H I; 1JWH C; 4NBA A; 2PMZ A; 2YAD A; 3CCU 1; 1VQ8 1; 2HU9 A; 1KC8 2; 3IR7 A; 1YJN Z; 1YHQ Z; 1P9N A; 2KPI A; 5E6R B; 1Z03 A; 2O4H A; 1QVF Z; 4HGY A; 5C4X I; 3CMA 1; 3TE5 B; 2E2I I; 2R92 I; 2VDM B; 2NAP A; 3GTM S; 3I55 1; 2JA5 I; 5T64 A; #chains in the Genus database with same CATH homology 1K9M 1; 1VQ5 Z; 1M1K 2; 3NH8 A; 3OW2 Y; 4NBG A; 1QYP A; 3CCV Z; 3CC2 1; 2YU9 I; 1YIJ Z; 4QTU A; 3CD6 1; 3CCJ Z; 1Q7Y 1; 2VUM I; 2PM9 A; 3S15 I; 1VQN 1; 5C44 I; 3J7A 4; 3QWU A; 4DK1 A; 2JNY A; 3S1Q I; 4A3G I; 3GTK I; 1YI2 1; 1RO2 A; 2QRC B; 2H85 A; 1QF8 A; 1Y1V S; 1YHQ 1; 2JUB A; 4E2W A; 2R7Z I; 4RVD A; 1L1O C; 2GTH A; 3IF8 A; 1RO4 A; 2IZ4 A; 3EER A; 2QR1 B; 3H0G I; 5FLM I; 1Q81 1; 2VDR B; 2VF1 A; 5IT9 b; 2QKD A; 4A3J I; 1TWC I; 3PO3 S; 3IFU A; 5IT9 f; 1VQ4 Z; 3RZO I; 1YIJ 1; 2Y0S A; 3CCJ 1; 2JS4 A; 1RO0 A; 4WJK B; 5D1P A; 2BJO A; 2QA4 Z; 3CCU Z; 4A3B I; 4RVG A; 4A3D I; 5LL6 f; 3G71 1; 3CPW Y; 1KRL A; 4XX2 A; 1Q86 1; 1DL6 A; 3D6W A; 4MON A; 3T3P B; 5C4J I; 3I55 Z; 4UM9 B; 1OLZ A; 3CCL 1; 4E31 A; 2RBL A; 2E9H A; 1KC8 1; 4BY7 I; 1ML8 A; 3CCE Z; 3CQZ I; 3ZE2 B; 4MD8 A; 3J81 b; 4A3M I; 4Z7N B; 4RVH A; 1S7M A; 5IP9 I; 1I6H I; 1TYE B; 1VQO Z; 1VQN Z; 1VQ4 1; 1PFT A; 3GCF A; 4WK2 B; 1X3W A; 4MD9 A; 1M1K 1; 4NBC A; 1QVF Y; 1VQM Z; 3ZE1 B; 4MD7 A; 1W2B Z; 1YI2 Z; 1RQF A; 2PK7 A; 2QA4 1; 1JJ2 Z; 3S14 I; 3CC7 Z; 3NH4 A; 2DE7 A; 4E30 A; 5FLX b; 3Q87 A; 4EWC A; 2JWG A; 2RT9 A; 2JR6 A; 5FLX f; 4AYB A; 5A2Q b; 2G2K A; 4E33 A; 5A2Q f; 2OOX B; 2DE5 A; 3MZK B; 2R6M A; 1YUA A; 4E2Y A; 4E32 A; 2VDN B; 3VI4 B; 3CCE 1; 1TWG I; 4DQY B; 4HGZ A; 4BBS I; 2IZ3 A; 1ZB8 A; 1YJ9 1; 3CXC Z; 3ZDY B; 2F4M A; 2JMO A; 3AL8 A; 3T3M B; 1VQO 1; 1LQL A; 3HOU I; 3S2D I; 2DE6 A; 5T67 A; 4S1T A; 3J80 f; 4X6A I; 1WW9 A; 1ZB9 A; 3G71 Z; 1VQM 1; 3I56 1; 2I3C A; 3G6E Z; 3CC7 1; 1U8C B; 3S1N I; 3HOW I; 3NIG B; 1YJW Z; 4A3K I; 4NOZ A; 3CCL Z; 2VDO B; 3NFZ A; 4NB8 A; 2QLV B; 3NDJ A; 4A3I I; 1S72 Z; 3KIF A; 2QEX 1; 1VQ6 Z; 2EGT A; 3OL2 A; 3M4O I; 2JA6 I; 4RS4 A; 3G4S Z; 2HF1 A; 2OTL 1; 1RLY A; 4QTT A; 3T4N B; 2V8K A; 3ESW A; 3HOV I; 2QRE B; 4K3J B; 3CCQ Z; 4Z7Q B; 1QVG Z; 3CC4 Z; 2V8J A; 1VQL Z; 4A3C I; 1N8R 2; 2NVT I; 3GTP I; 3G6E 1; 3HOX I; 4NFR A; 1Z02 A; 1YJW 1; 3CCM Z; 4Y52 I; 2UZY B; 2NVX I; 4NBE A; 3D9X A; 1S72 1; 3F3P C; 3VMH A; 1W2B Y; 1VQ6 1; 3JAM b; 4A3F I; 3G4S 1; 1K83 I; 1USP A; 1YJ9 Z; 1JJ2 Y; 3S1M I; 3JAM f; 3M3Y I; 2LFU A; 2AKL A; 1N2F A; 1X0T A; 3VMI A; 5C3E I; 2M48 A; 1NUI A; 1TFI A; 3BG0 B; 3NDI A; 3GTM I; 2LIY A; 3I56 Z; 3CCQ 1; 1K8A 2; 1K73 2; 4O3T B; 3OKW A; 2K3R A; 3EED A; 2NVQ I; 4UM9 D; 4A3L I; 4RV9 A; 3CC4 1; 4Z7O B; 2NVY I; 1WCM I; 1VQL 1; 3CCR Z; 2VUG A; 1Q82 2; 4NBB A; 1KQS Z; 3ZDZ B; 2VC2 B; 1KD1 1; 1SHY B; 2QRD B; 3CXC Y; 2QEX Z; 3CCM 1; 1M90 2; 4A3E I; 4NB9 A; 3S1R I; 2Q4Z A; 3AL8 B; 4Y7N I; 3FKI I; 1TWH I; 3GTQ I; 3S16 I; 2OTL Z; 4A93 I; 3FQM A; 4MRI A; 3F3F C; 2V8I A; 1R9T I; 4RVF A; 1Y1V I; 3I07 A; 1VQ9 Z; 3TDH B; 3LUS A; 2B63 I; 1NJI 2; 2O53 A; 3J80 b; 2OZK A; 4HH4 A; 1KD1 2; 2W03 A; 3VI3 B; 3OKY B; 3P5J B; 3VB9 A; 3CCS Z; 4CL1 A; 1Z01 A; 2WB1 A; 1X3Z A; 4TNU A; 3GTJ I; 3CME Z; 1WII A; 1TWF I; 1VLA A; 3FQQ A; 3K7A I; 4BXX I; 4UM8 B; 2VDQ B; 4MXU A; 3PO3 I; 3HOZ I; 3OL2 B; 3PO2 I; 3CCR 1; 3GKQ A; 5E6U B; 2P26 A; 3H3V J; 1YIT 1; 3OW2 Z; 2OTJ Z; 3NVQ A; 1N8R 1; 1VQ7 1; 4DGL A; 3FCU B; 1K9M 2; 4E2Z A; 1QVG Y; 1VQP Z; 2RHB A; 1RNI A; 1YJN 1; 3KIH A; 2VDL B; 3MON A; 1I3Q I; 2J6A A; 1YUK A; 1ZH1 A; 3IX0 A; 4GZ8 A; 1NP6 A; 1VQ9 1; 3ZDX B; 5E6S B; 1Q7Y 2; 3I4N I; 2GU2 A; 4NBD A; 1VQK Z; 2VDP B; 4BY1 I; 4FWW A; 3HKZ A; 3BG1 B; 1VQ5 1; 2RPR A; 5D1O B; 2E2J I; 3CCS 1; 2JA7 I; 3CCV 1; 2P28 A; 3CME 1; 3NIF B; 4BBR I; 1SSL A; 5AN9 F; 1TWA I; 3U50 C; 1K8A 1; 2WAQ A; 1K73 1; 1USP B; 5D1O A; 3I4M I; 3NID B; 3GTO I; 2R93 I; 1VQ8 Z; 3MZL B; 1SFO I; 1Y1W I; 2Q51 A; 3AL9 A; 2OTJ 1; 2F4O A; 2M6N A; 1Q82 1; 5IP7 I; 2JA8 I; 5HDB B; 4WK4 B; 4NBH A; 2ZAE B; 2K5R A; 1Q81 2; 3GTL I; 2GTI A; 3CMA Z; 1VQP 1; 2RIQ A; 2KI7 B; 3AFC A; 5CM2 M; 1M90 1; 3S17 I; 3HOY I; 3ZE0 B; 2W04 A; 1KQS Y; 2OOY B; 2P3Y A; 4MH4 A; 3VTN A; 3CPW Z; 1I50 I; 3CC2 Z; 4E2X A; 1VQK 1; 3S2H I; 3RZD I; 3CD6 Z; 4WK0 B; 3J81 f; 1NJI 1; 2VDK B; 1YIT Z; 5T6B A; 1Q86 2; 4NH1 C; 3VMG A; 4O3U B; 2JWH A; 4NBF A; 1VQ7 Z; 3GTG I; 3NH5 A; 2E2H I; 1JWH C; 4NBA A; 2PMZ A; 2YAD A; 3CCU 1; 1VQ8 1; 2HU9 A; 1KC8 2; 1YJN Z; 1YHQ Z; 1P9N A; 2KPI A; 5E6R B; 1Z03 A; 2O4H A; 1QVF Z; 4HGY A; 5C4X I; 3CMA 1; 3TE5 B; 2E2I I; 2R92 I; 2VDM B; 3GTM S; 3I55 1; 2JA5 I; 5T64 A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
