4HSI | Genus

Total Genus 128

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	128
sequence length	619
structure length	601
Chain Sequence	KAENTDANFYVCPPPTGATVVQFEQPRRCPTRPEGQNYTEGIAVVFKENIAPYKFKATMYYKDVTVSQVWFGHRYSQFMGIFEDRAPVPFEEVIDKINAKGVCRSTAKYVRNNLETTAFHRDDHETDMELKPANAATRTSRGWHTTDLKYNPSRVEAFHRYGTTVNCIVEEVDARSVYPYDEFVLATGDFVYMSPFYGYREGSHTEHTSYAADRFKQVDGFYARDLTTKARATAPTTRNLLTTPKFTVAWDWVPKRPSVCTMTKWQEVDEMLRSEYGGSFRFSSDAISTTFTTNLTEYPLSRVDLGDCIGKDARDAMDRIFARRYNATHIKVGQPQYYLANGGFLIAYQPLLSNTLAELYVREHLREQSVERIKTTSSIEFPGLGFTYGHIQRHVNDMLGRVAIAWCELQNHELTLWNEARKLNPNAIASVTVGRRVSARMLGDVMAVSTCVPVAADNVIVQNSMRISSRPGACYSRPLVSFRYEDQGPLVEGQLGENNELRLTRDAIEPCTVGHRRYFTFGGGYVYFEEYAYSHQLSRADITTVSTFIDLNITMLEDHEFVPLEVYTRHEIKDSGLLDYTEVQRRNQLHDLRFADIDTVI

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Viral protein
source organism	Human herpesvirus 1
publication title	Extensive Mutagenesis of the HSV-1 gB Ectodomain Reveals Remarkable Stability of Its Postfusion Form. pubmed doi rcsb
molecule keywords	Envelope glycoprotein B
total genus	128
structure length	601
sequence length	619
chains with identical sequence	B, C, D
ec nomenclature
pdb deposition date	2012-10-30

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00606	Glycoprotein_B	Herpesvirus Glycoprotein B ectodomain
A	PF17416	Glycoprot_B_PH1	Herpesvirus Glycoprotein B
A	PF17417	Glycoprot_B_PH2	Herpesvirus Glycoprotein B PH-like domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.30.29.100	Mainly Beta	Roll	PH-domain like	PH-domain like	4hsiA03
3.30.1450.20	Alpha Beta	2-Layer Sandwich	Beta-lactamase Inhibitory Protein; Chain:B, domain 1	Beta-lactamase Inhibitory Protein; Chain:B, domain 1	4hsiA01

3FVCA 2GUMA 4OSNA 3NWDA 4HSIA 3NWAA 4L1RA 4OT1A 3NW8A 3NWFA
chains in the Genus database with same CATH superfamily

2DX1A 1QC6A 4C0AA 1W1DA 1WJMA 2ROZB 2Z59A 4KHAA 1B55A 4K2OA 4Z2NA 4GN1A 3DXCA 1WI1A 5JHHA 5KQ1A 4KHBB 2YS3A 2DA0A 2RUKB 3ML4A 1UNPA 3SUZA 3RCPA 2Y7BA 4H8SA 3HW2B 3TVVA 2D9WA 4HB0B 1FHWA 4ZRJA 2KR0A 2YS5A 4IFSA 3ZDTA 2GCJA 1W1GA 3NSUA 1FOEA 3PSCA 5FI0A 2DN6A 3U8ZA 1EAZA 2EMSA 3P7ZA 3TW1A 4F7HA 4GPTB 3WA0A 2D2QA 3DXEA 2LG1A 3TCAA 4HAUB 1W1HA 2NZ8B 1X1GA 5EFXA 1PMSA 2KIGA 4GMXB 1X1FA 3V5WA 3BJIA 1U5DA 3NWDA 1QQGA 3AU4A 3NWAA 4QJ5B 2GUMA 4GZUA 5J3QA 1NI2A 2GS0A 2KIEA 2LKOA 3GYPA 3FM8C 2DTCA 1WVHA 1P5TA 1DROA 5C5BA 2MDXA 1MIXA 1WGQA 1MK7B 1UPRA 2I1KA 3FSSA 3QBVB 4DX90 1I7AA 1OQNA 3A98B 1KZGA 1DDWA 5JHGA 2K49A 1XX0A 2M38A 3QIJA 1SGHA 2NBVA 4Y94A 1U5GA 1FGZA 2YSZA 1U29A 4NY0A 1Y5OA 3PVUA 3C4PB 3VIAA 5HE1A 2GCLA 3D8FA 2E2XA 2H7DA 2P0DA 1FGYA 1V5MA 5KQ4A 3N7CA 4TKNA 4YL8A 1EVHA 5GOWB 1WG7A 2X18A 3HSAA 2ELBA 2R0DA 1MPHA 2KXXA 1MIZB 2G35A 1J0WA 3GYOA 4D6WA 3SNHA 3ULCA 2YF0A 2EJ8A 3KSYA 1ZM0A 1J19A 2ROVA 3N4IB 2COAA 4QJ3B 2PZ1A 3SYXA 1V5UA 5HE2A 1I2HA 5LOPB 1E5WA 1ISNA 5IRSA 2KM7A 1P3RA 4A5KA 5EKQE 4HDOA 2D9ZA 3FVCA 1DBHA 1DDVA 1FAOA 4BBKA 4PNKA 2DFKA 2K2UA 5HE3A 3T06A 1NU2A 1BWNA 4EJNA 1X86A 5D3YA 1Y19B 2DHIA 2RVBB 3M1IB 2I1JA 1V61A 5DHAB 2UZRA 1M7EA 4CHMA 1U2BA 3HIEA 2AL6A 3C4OB 4DM5A 2D9XA 1JTGB 2R2YA 4GMVA 1GG3A 1Z87A 2I5CA 1X11A 3E2LC 3UZTA 2BCJA 1ZSQA 3E2KC 2D11A 4KAXB 5JLJB 1EGXA 4F7GA 2Z0OA 2YRYA 3DCXA 2MKRA 2P0HA 2M14A 3ODWA 2W2XC 4EMOA 2QKLA 2PXGA 4EKUA 4D0NB 2QKMA 2MFQA 5C5BB 2DYQA 1UNRA 1WGUA 3U7DA 2AEHA 5KCVA 1ZVRA 5D0QE 3FEHA 3ODXA 3SV1A 1UPQA 1RRPB 2D10A 2MWNB 1OMWA 3ODOA 2IFSA 3X23A 3MDBC 2EC1A 2YT0A 5DH9B 2VRWB 3KY9A 5C16A 1LW3A 4WJ7A 1H10A 2ZPYA 1V88A 3A8QA 4KHOA 1MI1A 1ZC4B 2RLOA 2CY4A 1AWEA 4TYZA 4A6FA 1SHCA 3HQCA 5J3TA 5M4YB 2KCJA 1XCGA 2RSGA 2ELAA 4HB3B 1GC6A 2RRFA 2N23A 3NWFA 2FJLA 4K17A 5I2MA 3F5RA 4WVFB 3O96A 4DXAB 2J0JA 1MKEA 2G2UB 1LB1A 2G2WB 1P6SA 1PLSA 2HTHB 3TO1A 1NTVA 3QWMA 1IRSA 4OT1A 1MAIA 5D27A 2YT2A 1K5GB 4MK0A 3AU5A 2VKIA 2Z4DA 2L1CA 4DIXA 5C6RA 5D3XA 4CHJA 2Z13A 5HE0A 2RGNB 5CLLB 3WYFB 5DI9B 4HAZB 1U5EA 1TQZA 2Z14A 5CLQB 3DXDA 4K81A 3PEGA 4HSIA 4P7IA 3ULBA 2CAYA 3HK0A 2H7EA 1UEFA 2KUPA 1OY2A 3KRXA 4HAWB 2L2IA 1KZ7A 2Q13A 2RNRB 1K5DB 4DBBA 2Z0QA 3G9WA 3KZ1A 3U12A 4ZRIA 1ZC3B 4HAYB 3BINA 3P6AA 2J0KA 2K8EA 4A6HA 1ZYIA 5DIFB 4QJ4B 1XD4A 3A8PA 2DHKA 1M7RA 4CSQA 5L81A 1NTYA 2ADZA 4HB2B 4K2PA 3TFMA 1XXMC 2GJYA 2DYNA 2VSZA 4L1RA 5D3VA 3C7UB 2DX5A 5I2SA 2V76A 1MK9B 2W2XD 2YVCA 4WSFA 3CXBB 5J3YA 2CODA 3F0WA 2LULA 1FHOA 3NW8A 2YT1A 4KHBA 1FHXA 4A6FB 2N0YA 1XR0B 4HAVB 4F7UP 2NMBA 4CYEA 2ZKMX 1UNQA 2J59M 1X05A 2OTXA 2R09A 2P8VA 3AJ4A 2J0MA 3KRWA 5LG4B 1PFJA 3MPXA 1AQCA 3VOQA 2D4QA 2OQBA 2LOXA 1KI1B 1DYNA 3PZDA 4HAXB 3OHMB 2COCA 2Z0PA 4MT7A 2P0FA 4A6KA 2IYBA 4Z2MB 2YS1A 1WJ1A 5D3WA 2FJUB 1EF1A 3C7VB 3IVFA 4GXBA 4XWXA 2DHJA 2UVMA 2DKPA 4IAPA 1GC7A 1U5FA 4KVGB 2COFA 2K00A 5AYWE 2K2JA 4HB4B 1BAKA 3SO6A 3D8EA 4HATB 2Y8FA 3OANA 4GNKB 4YONA 5C79A 1BTNA 2CRFA 2Y8GA 1U27A 1RJ2A 1XKEA 3PG7A 4L6EA 4DX8A 1TJ6A 4ZRKA 2XQNM 2HE7A 2UZSA 3PP2A 1S0WC 2DLWA 4OSNA 1FB8A 3PVLA 2D9VA 2B5RC 1V5PA 3D4EA 4B6HA 3LJUX 2DKQA 4PQ0A 3D8DA 4IOYX 2KUQA 1BTKA 1DDMA 4HDQA 5DHFB 5D0OE 2D9YA 1V89A 2LOZA 1T77A 1TXDA 2KGXB 3A58A 3ZVRA 5JP4A 4QXAB 5LONB 1H4RA 2YH9A 3B77A 4GOUA 2LYDA 2EMTA 3CIKA 2I5FA 1XODA 4NSWA 2CY5A 2JP2A 2W2WA 5FI1A 4MY6A 4HHVA 3GMUB 1N3HA 1Q67A 3PVWA
chains in the Genus database with same CATH topology

2KXXA 4KHBA 3GYOA 4D6WA 2Z59A 4KHAA 4Z2NA 5M4YB 3N4IB 4KHBB 4QJ3B 5IRSA 3TVVA 2KM7A 2RRFA 2ZKMX 3NWFA 5EKQE 5I2MA 3FVCA 2KR0A 5LG4B 4IFSA 2GCJA 2G2UB 2G2WB 3TO1A 3OHMB 4OT1A 3TW1A 2YT2A 4Z2MB 2Z4DA 2FJUB 3C7VB 4DIXA 2KIGA 2Z13A 3HIEA 3C4OB 2Z14A 4DM5A 3NWDA 1JTGB 2R2YA 3NWAA 5AYWE 4HSIA 3E2LC 4QJ5B 2GUMA 4GNKB 3E2KC 2KIEA 3GYPA 3FSSA 2PXGA 1S0WC 2K49A 4OSNA 3U12A 2NBVA 5D0QE 2B5RC 3D4EA 2K8EA 1ZYIA 4QJ4B 4PQ0A 4IOYX 4CSQA 2KUQA 1XXMC 3C4PB 5D0OE 4L1RA 3A58A 2GCLA 3C7UB 4QXAB 2YH9A 5I2SA 4GOUA 3GMUB 4KHOA 3NW8A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 3FVC A;  2GUM A;  4OSN A;  3NWD A;  4HSI A;  3NWA A;  4L1R A;  4OT1 A;  3NW8 A;  3NWF A; 
#chains in the Genus database with same CATH topology
 2DX1 A;  1QC6 A;  4C0A A;  1W1D A;  1WJM A;  2ROZ B;  2Z59 A;  4KHA A;  1B55 A;  4K2O A;  4Z2N A;  4GN1 A;  3DXC A;  1WI1 A;  5JHH A;  5KQ1 A;  4KHB B;  2YS3 A;  2DA0 A;  2RUK B;  3ML4 A;  1UNP A;  3SUZ A;  3RCP A;  2Y7B A;  4H8S A;  3HW2 B;  3TVV A;  2D9W A;  4HB0 B;  1FHW A;  4ZRJ A;  2KR0 A;  2YS5 A;  4IFS A;  3ZDT A;  2GCJ A;  1W1G A;  3NSU A;  1FOE A;  3PSC A;  5FI0 A;  2DN6 A;  3U8Z A;  1EAZ A;  2EMS A;  3P7Z A;  3TW1 A;  4F7H A;  4GPT B;  3WA0 A;  2D2Q A;  3DXE A;  2LG1 A;  3TCA A;  4HAU B;  1W1H A;  2NZ8 B;  1X1G A;  5EFX A;  1PMS A;  2KIG A;  4GMX B;  1X1F A;  3V5W A;  3BJI A;  1U5D A;  3NWD A;  1QQG A;  3AU4 A;  3NWA A;  4QJ5 B;  2GUM A;  4GZU A;  5J3Q A;  1NI2 A;  2GS0 A;  2KIE A;  2LKO A;  3GYP A;  3FM8 C;  2DTC A;  1WVH A;  1P5T A;  1DRO A;  5C5B A;  2MDX A;  1MIX A;  1WGQ A;  1MK7 B;  1UPR A;  2I1K A;  3FSS A;  3QBV B;  4DX9 0;  1I7A A;  1OQN A;  3A98 B;  1KZG A;  1DDW A;  5JHG A;  2K49 A;  1XX0 A;  2M38 A;  3QIJ A;  1SGH A;  2NBV A;  4Y94 A;  1U5G A;  1FGZ A;  2YSZ A;  1U29 A;  4NY0 A;  1Y5O A;  3PVU A;  3C4P B;  3VIA A;  5HE1 A;  2GCL A;  3D8F A;  2E2X A;  2H7D A;  2P0D A;  1FGY A;  1V5M A;  5KQ4 A;  3N7C A;  4TKN A;  4YL8 A;  1EVH A;  5GOW B;  1WG7 A;  2X18 A;  3HSA A;  2ELB A;  2R0D A;  1MPH A;  2KXX A;  1MIZ B;  2G35 A;  1J0W A;  3GYO A;  4D6W A;  3SNH A;  3ULC A;  2YF0 A;  2EJ8 A;  3KSY A;  1ZM0 A;  1J19 A;  2ROV A;  3N4I B;  2COA A;  4QJ3 B;  2PZ1 A;  3SYX A;  1V5U A;  5HE2 A;  1I2H A;  5LOP B;  1E5W A;  1ISN A;  5IRS A;  2KM7 A;  1P3R A;  4A5K A;  5EKQ E;  4HDO A;  2D9Z A;  3FVC A;  1DBH A;  1DDV A;  1FAO A;  4BBK A;  4PNK A;  2DFK A;  2K2U A;  5HE3 A;  3T06 A;  1NU2 A;  1BWN A;  4EJN A;  1X86 A;  5D3Y A;  1Y19 B;  2DHI A;  2RVB B;  3M1I B;  2I1J A;  1V61 A;  5DHA B;  2UZR A;  1M7E A;  4CHM A;  1U2B A;  3HIE A;  2AL6 A;  3C4O B;  4DM5 A;  2D9X A;  1JTG B;  2R2Y A;  4GMV A;  1GG3 A;  1Z87 A;  2I5C A;  1X11 A;  3E2L C;  3UZT A;  2BCJ A;  1ZSQ A;  3E2K C;  2D11 A;  4KAX B;  5JLJ B;  1EGX A;  4F7G A;  2Z0O A;  2YRY A;  3DCX A;  2MKR A;  2P0H A;  2M14 A;  3ODW A;  2W2X C;  4EMO A;  2QKL A;  2PXG A;  4EKU A;  4D0N B;  2QKM A;  2MFQ A;  5C5B B;  2DYQ A;  1UNR A;  1WGU A;  3U7D A;  2AEH A;  5KCV A;  1ZVR A;  5D0Q E;  3FEH A;  3ODX A;  3SV1 A;  1UPQ A;  1RRP B;  2D10 A;  2MWN B;  1OMW A;  3ODO A;  2IFS A;  3X23 A;  3MDB C;  2EC1 A;  2YT0 A;  5DH9 B;  2VRW B;  3KY9 A;  5C16 A;  1LW3 A;  4WJ7 A;  1H10 A;  2ZPY A;  1V88 A;  3A8Q A;  4KHO A;  1MI1 A;  1ZC4 B;  2RLO A;  2CY4 A;  1AWE A;  4TYZ A;  4A6F A;  1SHC A;  3HQC A;  5J3T A;  5M4Y B;  2KCJ A;  1XCG A;  2RSG A;  2ELA A;  4HB3 B;  1GC6 A;  2RRF A;  2N23 A;  3NWF A;  2FJL A;  4K17 A;  5I2M A;  3F5R A;  4WVF B;  3O96 A;  4DXA B;  2J0J A;  1MKE A;  2G2U B;  1LB1 A;  2G2W B;  1P6S A;  1PLS A;  2HTH B;  3TO1 A;  1NTV A;  3QWM A;  1IRS A;  4OT1 A;  1MAI A;  5D27 A;  2YT2 A;  1K5G B;  4MK0 A;  3AU5 A;  2VKI A;  2Z4D A;  2L1C A;  4DIX A;  5C6R A;  5D3X A;  4CHJ A;  2Z13 A;  5HE0 A;  2RGN B;  5CLL B;  3WYF B;  5DI9 B;  4HAZ B;  1U5E A;  1TQZ A;  2Z14 A;  5CLQ B;  3DXD A;  4K81 A;  3PEG A;  4HSI A;  4P7I A;  3ULB A;  2CAY A;  3HK0 A;  2H7E A;  1UEF A;  2KUP A;  1OY2 A;  3KRX A;  4HAW B;  2L2I A;  1KZ7 A;  2Q13 A;  2RNR B;  1K5D B;  4DBB A;  2Z0Q A;  3G9W A;  3KZ1 A;  3U12 A;  4ZRI A;  1ZC3 B;  4HAY B;  3BIN A;  3P6A A;  2J0K A;  2K8E A;  4A6H A;  1ZYI A;  5DIF B;  4QJ4 B;  1XD4 A;  3A8P A;  2DHK A;  1M7R A;  4CSQ A;  5L81 A;  1NTY A;  2ADZ A;  4HB2 B;  4K2P A;  3TFM A;  1XXM C;  2GJY A;  2DYN A;  2VSZ A;  4L1R A;  5D3V A;  3C7U B;  2DX5 A;  5I2S A;  2V76 A;  1MK9 B;  2W2X D;  2YVC A;  4WSF A;  3CXB B;  5J3Y A;  2COD A;  3F0W A;  2LUL A;  1FHO A;  3NW8 A;  2YT1 A;  4KHB A;  1FHX A;  4A6F B;  2N0Y A;  1XR0 B;  4HAV B;  4F7U P;  2NMB A;  4CYE A;  2ZKM X;  1UNQ A;  2J59 M;  1X05 A;  2OTX A;  2R09 A;  2P8V A;  3AJ4 A;  2J0M A;  3KRW A;  5LG4 B;  1PFJ A;  3MPX A;  1AQC A;  3VOQ A;  2D4Q A;  2OQB A;  2LOX A;  1KI1 B;  1DYN A;  3PZD A;  4HAX B;  3OHM B;  2COC A;  2Z0P A;  4MT7 A;  2P0F A;  4A6K A;  2IYB A;  4Z2M B;  2YS1 A;  1WJ1 A;  5D3W A;  2FJU B;  1EF1 A;  3C7V B;  3IVF A;  4GXB A;  4XWX A;  2DHJ A;  2UVM A;  2DKP A;  4IAP A;  1GC7 A;  1U5F A;  4KVG B;  2COF A;  2K00 A;  5AYW E;  2K2J A;  4HB4 B;  1BAK A;  3SO6 A;  3D8E A;  4HAT B;  2Y8F A;  3OAN A;  4GNK B;  4YON A;  5C79 A;  1BTN A;  2CRF A;  2Y8G A;  1U27 A;  1RJ2 A;  1XKE A;  3PG7 A;  4L6E A;  4DX8 A;  1TJ6 A;  4ZRK A;  2XQN M;  2HE7 A;  2UZS A;  3PP2 A;  1S0W C;  2DLW A;  4OSN A;  1FB8 A;  3PVL A;  2D9V A;  2B5R C;  1V5P A;  3D4E A;  4B6H A;  3LJU X;  2DKQ A;  4PQ0 A;  3D8D A;  4IOY X;  2KUQ A;  1BTK A;  1DDM A;  4HDQ A;  5DHF B;  5D0O E;  2D9Y A;  1V89 A;  2LOZ A;  1T77 A;  1TXD A;  2KGX B;  3A58 A;  3ZVR A;  5JP4 A;  4QXA B;  5LON B;  1H4R A;  2YH9 A;  3B77 A;  4GOU A;  2LYD A;  2EMT A;  3CIK A;  2I5F A;  1XOD A;  4NSW A;  2CY5 A;  2JP2 A;  2W2W A;  5FI1 A;  4MY6 A;  4HHV A;  3GMU B;  1N3H A;  1Q67 A;  3PVW A; 
#chains in the Genus database with same CATH homology
 2KXX A;  4KHB A;  3GYO A;  4D6W A;  2Z59 A;  4KHA A;  4Z2N A;  5M4Y B;  3N4I B;  4KHB B;  4QJ3 B;  5IRS A;  3TVV A;  2KM7 A;  2RRF A;  2ZKM X;  3NWF A;  5EKQ E;  5I2M A;  3FVC A;  2KR0 A;  5LG4 B;  4IFS A;  2GCJ A;  2G2U B;  2G2W B;  3TO1 A;  3OHM B;  4OT1 A;  3TW1 A;  2YT2 A;  4Z2M B;  2Z4D A;  2FJU B;  3C7V B;  4DIX A;  2KIG A;  2Z13 A;  3HIE A;  3C4O B;  2Z14 A;  4DM5 A;  3NWD A;  1JTG B;  2R2Y A;  3NWA A;  5AYW E;  4HSI A;  3E2L C;  4QJ5 B;  2GUM A;  4GNK B;  3E2K C;  2KIE A;  3GYP A;  3FSS A;  2PXG A;  1S0W C;  2K49 A;  4OSN A;  3U12 A;  2NBV A;  5D0Q E;  2B5R C;  3D4E A;  2K8E A;  1ZYI A;  4QJ4 B;  4PQ0 A;  4IOY X;  4CSQ A;  2KUQ A;  1XXM C;  3C4P B;  5D0O E;  4L1R A;  3A58 A;  2GCL A;  3C7U B;  4QXA B;  2YH9 A;  5I2S A;  4GOU A;  3GMU B;  4KHO A;  3NW8 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4HSIA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations