1XD4 | Genus

Total Genus 279

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	279
sequence length	849
structure length	824
Chain Sequence	EQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSANDVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYARDILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESAAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEEGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIAHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPR

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Signaling protein
source organism	Homo sapiens
publication title	Structural analysis of autoinhibition in the ras activator son of sevenless. pubmed doi rcsb
molecule keywords	Son of sevenless protein homolog 1
total genus	279
structure length	824
sequence length	849
chains with identical sequence	B
ec nomenclature
pdb deposition date	2004-09-03

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00169	PH	PH domain
A	PF00617	RasGEF	RasGEF domain
A	PF00618	RasGEF_N	RasGEF N-terminal motif
A	PF00621	RhoGEF	RhoGEF domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.840.10	Mainly Alpha	Orthogonal Bundle	Son of Sevenless (SoS) protein; Chain S, domain 2	Ras guanine-nucleotide exchange factors catalytic domain	1xd4A04
1.20.870.10	Mainly Alpha	Up-down Bundle	Son of sevenless (SoS) protein; Chain S, domain 1	Son of sevenless (SoS) protein Chain: S domain 1	1xd4A03
1.20.900.10	Mainly Alpha	Up-down Bundle	Dbl Homology Domain; Chain A	Dbl homology (DH) domain	1xd4A01
2.30.29.30	Mainly Beta	Roll	PH-domain like	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	1xd4A02

2D10A 1EAZA 3QXLA 3SV1A 1PFJA 4HB4B 1W1HA 2CODA 1UEFA 4CYEA 3D8EA 1J19A 2DKQA 3DXEA 1NVWS 3PEGA 2Y8GA 4ZRKA 1QQGA 1MIXA 3N7CA 4MY6A 3CIKA 2YT0A 3BJIA 1NVUS 4ZRIA 3ULCA 4JGWA 1KZ7A 1MPHA 5C79A 5D3XA 5JHHA 1MK7B 1KZGA 4F7ZA 2YS1A 2G35A 4IOYX 3HK0A 3A8PA 2DX1A 1LW3A 2Y7BA 1BTNA 2QKMA 3CXBB 2KCJA 3PSCA 3TCAA 2QKLA 2EJ8A 5CM8A 2MDXA 2DN6A 2H7EA 2YT1A 4GMXB 4A6FA 3VIAA 1OMWA 4GN1A 1P5TA 4KHBB 2D9YA 3G9WA 3GYPA 4HB3B 1V5UA 2CRFA 2ADZA 4GOUA 4B6HA 1GC6A 2N0YA 3A8QA 1TJ6A 1F5XA 4A6HA 2AEHA 4MT7A 1WG7A 2DHIA 4URXS 2DA0A 4A6KA 4KAXB 1QC6A 5DIFB 1WJ1A 1EF1A 2VKIA 2UZSA 4A6FB 4PQ0A 1XKEA 3ML4A 2Y8FA 2RVBB 3SYXA 2MFQA 5CLQB 2W2WA 2N23A 4F7GA 4URVS 2LOZA 3OANA 4H8SA 2VSZA 3BINA 1U2BA 3NSUA 1Y5OA 4DX8A 3GF9A 1LB1A 5D27A 4Y94A 5FI1A 1NTYA 3A98B 3RCPA 3TFMA 4HDQA 3KRWA 4XWXA 4WSFA 1ZSQA 1UPRA 3IVFA 2DFKA 4NSWA 5LONB 1OY2A 1XODA 5L81A 4US2S 3FSSA 3PVLA 3WA0A 4HAZB 1U5DA 1X86A 2OTXA 2E2XA 4NYIS 1P6SA 3WYFB 2DX5A 2UZRA 1UNPA 1I7AA 1WGQA 2EC1A 3PP2A 5EFXA 3ZDTA 1FHOA 4DXAB 5C16A 2GJYA 2Z0PA 2W2XD 4K2PA 5JP4A 2COFA 2RUKB 1FHXA 4MGKE 1E5WA 2I1KA 3KRXA 2Z0OA 4NYMS 3F5RA 1Y19B 4MH0E 2CY5A 5DHFB 2RGNB 3GYOA 3PZDA 4DBBA 2LULA 2COAA 1ISNA 2DHJA 2PZ1A 2LG1A 2DHKA 1DROA 2UVMA 4HB0B 4NYJS 1FB8A 1U27A 2VRWB 5J3TA 1U5FA 5HE2A 2DKPA 1K5DB 4URUS 1X1FA 4MGYE 2D9VA 1DBHA 4US1S 4KVGB 4NY0A 1PMSA 3FEHA 3VOQA 4TKNA 2RNRB 2OQBA 3ODWA 2CY4A 1M7EA 1TQZA 1NVXS 4MK0A 5KQ4A 2YF0A 1RJ2A 3QBVB 2COCA 4GZUA 1ZM0A 3ZVRA 1KI1B 2YSZA 1V5MA 2V76A 1XX0A 2ROZB 2IYBA 2R0DA 4D0OA 2MKRA 3QWMA 4K81A 1FAOA 3DXCA 1X1GA 4GYVA 2EMTA 3X23A 5C5BA 4Z2NA 3O96A 2MWNB 2R09A 4F7HA 5J3YA 1BKDS 2YRYA 1Z87A 5CM9A 1X05A 4EMOA 4MGZE 2I1JA 3PVUA 4P7IA 2P8VA 2GCJA 3PG7A 4F7UP 4BBKA 1H10A 2D9XA 1IRSA 3V5WA 2NZ8B 1N3HA 1DYNA 2IFSA 5D3YA 5HE0A 4HDOA 4ZRJA 2ZPYA 4CHJA 3T06A 4TYZA 5C5BB 1V61A 1Q67A 3SO6A 5C6RA 1H4RA 2ELBA 2GCLA 2L1CA 2AL6A 1UNQA 1GC7A 3M1IB 1M7RA 2YS3A 3SUZA 1UNRA 2I5CA 5J3QA 3U8ZA 1ZC3B 2D4QA 3ODOA 3TVVA 3DXDA 1AQCA 3F0WA 5DI9B 2DYQA 2RLOA 1XD2C 4URWS 4Z2MB 4KHOA 4L9MA 1UPQA 3LJUX 2J0JA 1MK9B 2Q13A 3KZ1A 1FGYA 2H7DA 2BCJA 2J0KA 4HAWB 4WJ7A 4GXBA 4DX90 1P3RA 1FHWA 1WJMA 5DHAB 3TO1A 4D0NB 4HAUB 1J0WA 1I2HA 2II0A 1V89A 3AJ4A 5CLLB 2D11A 4IAPA 1MIZB 4A5KA 4GPTB 4HAYB 3ODXA 1B55A 3MDBC 5JHGA 4IFSA 3P6AA 2NMBA 1MAIA 2GS0A 2I5FA 1ZVRA 2IJES 1K5GB 4KHAA 2XQNM 2X18A 4EJNA 1NU2A 2J59M 2BYVE 2ROVA 1DDMA 2Z0QA 4C0AA 2K2JA 3TW1A 5HE3A 2HE7A 3T6GA 2KGXB 2JP2A 1TXDA 1MKEA 2DTCA 4K17A 3T6AA 3D8FA 5LOPB 1DDWA 4HHVA 2M14A 4L6EA 3AU4A 1NVVS 5D3WA 2LYDA 3HQCA 1FOEA 2KR9A 3AU5A 2KUPA 4MGIE 1DDVA 2EMSA 2D9ZA 1NTVA 1SHCA 1WI1A 5D3VA 1XCGA 2DLWA 3HW2B 1BTKA 1U5EA 4EKUA 3KSYA 2YVCA 2LOXA 3PVWA 1SGHA 2D2QA 4HATB 4URZS 5FI0A 2K00A 2FJLA 4YONA 5DH9B 2L2IA 4HAXB 4HB2B 1FGZA 3D8DA 1WGUA 3SNHA 2CAYA 2W2XC 1X11A 1WVHA 4CHMA 3UZTA 2K2UA 1V5PA 2P0HA 2RSGA 3QIJA 3P7ZA 1AWEA 2DYNA 2P0FA 1OQNA 4US0S 5JLJB 3EO2A 1GG3A 5KQ1A 2D9WA 5HE1A 3MPXA 4YL8A 1XR0B 3FM8C 2M38A 2YS5A 2LKOA 5KCVA 1NI2A 4PNKA 1XD4A 4K2OA 1U5GA 1BY1A 1RRPB 2P0DA 2ELAA 1PLSA 3KY9A 1W1GA 1ZC4B 3CF6E 1V88A 1EGXA 3JV3A 4GMVA 4HAVB 1W1DA 4URYS 4WVFB 1U29A 2HTHB 1BAKA 5GOWB 3ULBA 3U7DA 1BWNA 1EVHA 2J0MA
chains in the Genus database with same CATH superfamily

2D10A 1EAZA 3QXLA 3SV1A 1PFJA 4HB4B 5I2MA 1W1HA 2CODA 1UEFA 4CYEA 3D8EA 1J19A 2DKQA 3NWAA 3DXEA 1NVWS 3PEGA 3DCXA 2Y8GA 4ZRKA 3A58A 1QQGA 4CSQA 1MIXA 3N7CA 4DIXA 4MY6A 3CIKA 2YT0A 3BJIA 1NVUS 4ZRIA 3ULCA 4JGWA 2YT2A 1KZ7A 1MPHA 5C79A 5D3XA 5JHHA 1MK7B 1KZGA 4F7ZA 2YS1A 2G35A 4IOYX 3HK0A 3A8PA 2DX1A 1LW3A 2Y7BA 1BTNA 2QKMA 3CXBB 2KCJA 3PSCA 3TCAA 2QKLA 2EJ8A 5CM8A 2MDXA 2DN6A 2H7EA 2YT1A 4GMXB 4A6FA 3VIAA 1OMWA 4GN1A 4OT1A 1P5TA 4KHBB 2D9YA 3G9WA 3GYPA 4HB3B 1V5UA 2CRFA 2ADZA 4GOUA 4B6HA 1GC6A 3OHMB 2N0YA 3A8QA 1TJ6A 1F5XA 4A6HA 2AEHA 4MT7A 1WG7A 2DHIA 4URXS 2DA0A 4A6KA 4KAXB 1QC6A 5DIFB 1WJ1A 1EF1A 2VKIA 3U12A 2UZSA 4OSNA 4PQ0A 1XKEA 3ML4A 4A6FB 2Y8FA 2RVBB 3SYXA 2MFQA 5CLQB 2W2WA 2N23A 4F7GA 4URVS 5I2SA 2LOZA 3OANA 4H8SA 2K8EA 2VSZA 3BINA 1U2BA 3NSUA 1Y5OA 4DX8A 3GF9A 1LB1A 5D27A 4Y94A 5FI1A 1NTYA 3A98B 3RCPA 1ZYIA 3TFMA 4HDQA 3KRWA 4XWXA 4WSFA 1ZSQA 1UPRA 3IVFA 2DFKA 4NSWA 5LONB 1OY2A 1XODA 5L81A 4US2S 3FSSA 3PVLA 3WA0A 4HAZB 1U5DA 1X86A 2OTXA 2E2XA 4NYIS 1P6SA 3WYFB 2DX5A 2UZRA 1UNPA 1I7AA 1WGQA 2EC1A 3PP2A 5EFXA 2Z59A 3ZDTA 1FHOA 3HSAA 4DXAB 5LG4B 5C16A 2GJYA 2Z0PA 2W2XD 4K2PA 5JP4A 2COFA 2RUKB 1FHXA 5M4YB 4MGKE 1E5WA 3NW8A 2I1KA 4D6WA 3KRXA 2Z0OA 4NYMS 3F5RA 1Y19B 4MH0E 2CY5A 5DHFB 2RGNB 3GYOA 3PZDA 2K49A 4DBBA 2LULA 2COAA 1ISNA 2DHJA 2FJUB 2PZ1A 2LG1A 2DHKA 1DROA 2UVMA 4HB0B 4NYJS 1FB8A 1U27A 2VRWB 5J3TA 1U5FA 5HE2A 2DKPA 1K5DB 4URUS 1X1FA 4MGYE 2D9VA 1DBHA 4US1S 4KVGB 4NY0A 1PMSA 3FEHA 3VOQA 4TKNA 2KIEA 2RNRB 2OQBA 3ODWA 2CY4A 1M7EA 1TQZA 1NVXS 4MK0A 5KQ4A 2YF0A 1RJ2A 3QBVB 2COCA 4GZUA 1ZM0A 3ZVRA 1KI1B 2YSZA 4L1RA 1V5MA 2V76A 1XX0A 2ROZB 2IYBA 2R0DA 4D0OA 2MKRA 3QWMA 4K81A 1FAOA 3DXCA 1X1GA 4GYVA 2EMTA 3X23A 5C5BA 4Z2NA 3O96A 2MWNB 2R09A 4F7HA 5J3YA 1BKDS 3NWFA 2YRYA 1Z87A 5CM9A 1X05A 2Z14A 4EMOA 4MGZE 2I1JA 3PVUA 4P7IA 2P8VA 2GCJA 3PG7A 4F7UP 4BBKA 2R2YA 1H10A 2D9XA 3FVCA 1IRSA 3V5WA 2NZ8B 1N3HA 1DYNA 2IFSA 5D3YA 5HE0A 4HDOA 4ZRJA 2ZPYA 4CHJA 3T06A 4TYZA 5C5BB 1V61A 1Q67A 3SO6A 5C6RA 1H4RA 2ELBA 4QXAB 2GCLA 2L1CA 2AL6A 1UNQA 1GC7A 3M1IB 1M7RA 2YS3A 3SUZA 4GNKB 1UNRA 2I5CA 5J3QA 3U8ZA 1ZC3B 2D4QA 3ODOA 3TVVA 3DXDA 1AQCA 4QJ4B 3B77A 3F0WA 5DI9B 2DYQA 2RLOA 1XD2C 4URWS 4Z2MB 3NWDA 4KHOA 4L9MA 2KIGA 1UPQA 3LJUX 2J0JA 2GUMA 4HSIA 1MK9B 2Q13A 2KUQA 3KZ1A 1FGYA 2H7DA 2BCJA 1T77A 2J0KA 2Z4DA 4HAWB 4WJ7A 4GXBA 4DX90 1P3RA 1FHWA 1WJMA 5DHAB 3TO1A 4D0NB 4HAUB 1J0WA 1I2HA 2II0A 1V89A 3AJ4A 5CLLB 2D11A 4IAPA 1MIZB 4A5KA 4GPTB 4HAYB 3ODXA 1B55A 3MDBC 2NBVA 2Z13A 5JHGA 4IFSA 3P6AA 2NMBA 1MAIA 2GS0A 2I5FA 1ZVRA 2IJES 1K5GB 4KHAA 2XQNM 2X18A 4EJNA 1NU2A 2J59M 2BYVE 4KHBA 2ROVA 1DDMA 2Z0QA 4C0AA 2K2JA 3TW1A 5HE3A 2HE7A 3T6GA 2KGXB 2JP2A 1TXDA 1MKEA 2DTCA 4K17A 5IRSA 3T6AA 3D8FA 5LOPB 1DDWA 4HHVA 2M14A 4L6EA 3AU4A 1NVVS 5D3WA 2LYDA 3HQCA 1FOEA 2KR9A 3AU5A 2KUPA 4MGIE 1DDVA 2EMSA 2D9ZA 1NTVA 1SHCA 1WI1A 5D3VA 1XCGA 2DLWA 3HW2B 1BTKA 1U5EA 4EKUA 3KSYA 2YVCA 2LOXA 3PVWA 3HIEA 1SGHA 2D2QA 4HATB 4URZS 5FI0A 2K00A 2FJLA 4YONA 5DH9B 2L2IA 4HAXB 4HB2B 1FGZA 3D8DA 2ZKMX 1WGUA 3SNHA 2CAYA 2W2XC 1X11A 2RRFA 1WVHA 4CHMA 3UZTA 2K2UA 1V5PA 2P0HA 4QJ5B 4QJ3B 2RSGA 3QIJA 3P7ZA 1AWEA 2DYNA 2P0FA 1OQNA 2KR0A 4US0S 5JLJB 3EO2A 1GG3A 5KQ1A 2D9WA 5HE1A 3MPXA 4YL8A 1XR0B 3FM8C 2M38A 2YS5A 2LKOA 5KCVA 1NI2A 4PNKA 1XD4A 4K2OA 1U5GA 1BY1A 1RRPB 2P0DA 2ELAA 1PLSA 3KY9A 1W1GA 1ZC4B 3CF6E 1V88A 1EGXA 3JV3A 1MI1A 4GMVA 4HAVB 1W1DA 4URYS 4WVFB 1U29A 2HTHB 1BAKA 5GOWB 3ULBA 3U7DA 1BWNA 1EVHA 2J0MA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2D10 A;  1EAZ A;  3QXL A;  3SV1 A;  1PFJ A;  4HB4 B;  1W1H A;  2COD A;  1UEF A;  4CYE A;  3D8E A;  1J19 A;  2DKQ A;  3DXE A;  1NVW S;  3PEG A;  2Y8G A;  4ZRK A;  1QQG A;  1MIX A;  3N7C A;  4MY6 A;  3CIK A;  2YT0 A;  3BJI A;  1NVU S;  4ZRI A;  3ULC A;  4JGW A;  1KZ7 A;  1MPH A;  5C79 A;  5D3X A;  5JHH A;  1MK7 B;  1KZG A;  4F7Z A;  2YS1 A;  2G35 A;  4IOY X;  3HK0 A;  3A8P A;  2DX1 A;  1LW3 A;  2Y7B A;  1BTN A;  2QKM A;  3CXB B;  2KCJ A;  3PSC A;  3TCA A;  2QKL A;  2EJ8 A;  5CM8 A;  2MDX A;  2DN6 A;  2H7E A;  2YT1 A;  4GMX B;  4A6F A;  3VIA A;  1OMW A;  4GN1 A;  1P5T A;  4KHB B;  2D9Y A;  3G9W A;  3GYP A;  4HB3 B;  1V5U A;  2CRF A;  2ADZ A;  4GOU A;  4B6H A;  1GC6 A;  2N0Y A;  3A8Q A;  1TJ6 A;  1F5X A;  4A6H A;  2AEH A;  4MT7 A;  1WG7 A;  2DHI A;  4URX S;  2DA0 A;  4A6K A;  4KAX B;  1QC6 A;  5DIF B;  1WJ1 A;  1EF1 A;  2VKI A;  2UZS A;  4A6F B;  4PQ0 A;  1XKE A;  3ML4 A;  2Y8F A;  2RVB B;  3SYX A;  2MFQ A;  5CLQ B;  2W2W A;  2N23 A;  4F7G A;  4URV S;  2LOZ A;  3OAN A;  4H8S A;  2VSZ A;  3BIN A;  1U2B A;  3NSU A;  1Y5O A;  4DX8 A;  3GF9 A;  1LB1 A;  5D27 A;  4Y94 A;  5FI1 A;  1NTY A;  3A98 B;  3RCP A;  3TFM A;  4HDQ A;  3KRW A;  4XWX A;  4WSF A;  1ZSQ A;  1UPR A;  3IVF A;  2DFK A;  4NSW A;  5LON B;  1OY2 A;  1XOD A;  5L81 A;  4US2 S;  3FSS A;  3PVL A;  3WA0 A;  4HAZ B;  1U5D A;  1X86 A;  2OTX A;  2E2X A;  4NYI S;  1P6S A;  3WYF B;  2DX5 A;  2UZR A;  1UNP A;  1I7A A;  1WGQ A;  2EC1 A;  3PP2 A;  5EFX A;  3ZDT A;  1FHO A;  4DXA B;  5C16 A;  2GJY A;  2Z0P A;  2W2X D;  4K2P A;  5JP4 A;  2COF A;  2RUK B;  1FHX A;  4MGK E;  1E5W A;  2I1K A;  3KRX A;  2Z0O A;  4NYM S;  3F5R A;  1Y19 B;  4MH0 E;  2CY5 A;  5DHF B;  2RGN B;  3GYO A;  3PZD A;  4DBB A;  2LUL A;  2COA A;  1ISN A;  2DHJ A;  2PZ1 A;  2LG1 A;  2DHK A;  1DRO A;  2UVM A;  4HB0 B;  4NYJ S;  1FB8 A;  1U27 A;  2VRW B;  5J3T A;  1U5F A;  5HE2 A;  2DKP A;  1K5D B;  4URU S;  1X1F A;  4MGY E;  2D9V A;  1DBH A;  4US1 S;  4KVG B;  4NY0 A;  1PMS A;  3FEH A;  3VOQ A;  4TKN A;  2RNR B;  2OQB A;  3ODW A;  2CY4 A;  1M7E A;  1TQZ A;  1NVX S;  4MK0 A;  5KQ4 A;  2YF0 A;  1RJ2 A;  3QBV B;  2COC A;  4GZU A;  1ZM0 A;  3ZVR A;  1KI1 B;  2YSZ A;  1V5M A;  2V76 A;  1XX0 A;  2ROZ B;  2IYB A;  2R0D A;  4D0O A;  2MKR A;  3QWM A;  4K81 A;  1FAO A;  3DXC A;  1X1G A;  4GYV A;  2EMT A;  3X23 A;  5C5B A;  4Z2N A;  3O96 A;  2MWN B;  2R09 A;  4F7H A;  5J3Y A;  1BKD S;  2YRY A;  1Z87 A;  5CM9 A;  1X05 A;  4EMO A;  4MGZ E;  2I1J A;  3PVU A;  4P7I A;  2P8V A;  2GCJ A;  3PG7 A;  4F7U P;  4BBK A;  1H10 A;  2D9X A;  1IRS A;  3V5W A;  2NZ8 B;  1N3H A;  1DYN A;  2IFS A;  5D3Y A;  5HE0 A;  4HDO A;  4ZRJ A;  2ZPY A;  4CHJ A;  3T06 A;  4TYZ A;  5C5B B;  1V61 A;  1Q67 A;  3SO6 A;  5C6R A;  1H4R A;  2ELB A;  2GCL A;  2L1C A;  2AL6 A;  1UNQ A;  1GC7 A;  3M1I B;  1M7R A;  2YS3 A;  3SUZ A;  1UNR A;  2I5C A;  5J3Q A;  3U8Z A;  1ZC3 B;  2D4Q A;  3ODO A;  3TVV A;  3DXD A;  1AQC A;  3F0W A;  5DI9 B;  2DYQ A;  2RLO A;  1XD2 C;  4URW S;  4Z2M B;  4KHO A;  4L9M A;  1UPQ A;  3LJU X;  2J0J A;  1MK9 B;  2Q13 A;  3KZ1 A;  1FGY A;  2H7D A;  2BCJ A;  2J0K A;  4HAW B;  4WJ7 A;  4GXB A;  4DX9 0;  1P3R A;  1FHW A;  1WJM A;  5DHA B;  3TO1 A;  4D0N B;  4HAU B;  1J0W A;  1I2H A;  2II0 A;  1V89 A;  3AJ4 A;  5CLL B;  2D11 A;  4IAP A;  1MIZ B;  4A5K A;  4GPT B;  4HAY B;  3ODX A;  1B55 A;  3MDB C;  5JHG A;  4IFS A;  3P6A A;  2NMB A;  1MAI A;  2GS0 A;  2I5F A;  1ZVR A;  2IJE S;  1K5G B;  4KHA A;  2XQN M;  2X18 A;  4EJN A;  1NU2 A;  2J59 M;  2BYV E;  2ROV A;  1DDM A;  2Z0Q A;  4C0A A;  2K2J A;  3TW1 A;  5HE3 A;  2HE7 A;  3T6G A;  2KGX B;  2JP2 A;  1TXD A;  1MKE A;  2DTC A;  4K17 A;  3T6A A;  3D8F A;  5LOP B;  1DDW A;  4HHV A;  2M14 A;  4L6E A;  3AU4 A;  1NVV S;  5D3W A;  2LYD A;  3HQC A;  1FOE A;  2KR9 A;  3AU5 A;  2KUP A;  4MGI E;  1DDV A;  2EMS A;  2D9Z A;  1NTV A;  1SHC A;  1WI1 A;  5D3V A;  1XCG A;  2DLW A;  3HW2 B;  1BTK A;  1U5E A;  4EKU A;  3KSY A;  2YVC A;  2LOX A;  3PVW A;  1SGH A;  2D2Q A;  4HAT B;  4URZ S;  5FI0 A;  2K00 A;  2FJL A;  4YON A;  5DH9 B;  2L2I A;  4HAX B;  4HB2 B;  1FGZ A;  3D8D A;  1WGU A;  3SNH A;  2CAY A;  2W2X C;  1X11 A;  1WVH A;  4CHM A;  3UZT A;  2K2U A;  1V5P A;  2P0H A;  2RSG A;  3QIJ A;  3P7Z A;  1AWE A;  2DYN A;  2P0F A;  1OQN A;  4US0 S;  5JLJ B;  3EO2 A;  1GG3 A;  5KQ1 A;  2D9W A;  5HE1 A;  3MPX A;  4YL8 A;  1XR0 B;  3FM8 C;  2M38 A;  2YS5 A;  2LKO A;  5KCV A;  1NI2 A;  4PNK A;  1XD4 A;  4K2O A;  1U5G A;  1BY1 A;  1RRP B;  2P0D A;  2ELA A;  1PLS A;  3KY9 A;  1W1G A;  1ZC4 B;  3CF6 E;  1V88 A;  1EGX A;  3JV3 A;  4GMV A;  4HAV B;  1W1D A;  4URY S;  4WVF B;  1U29 A;  2HTH B;  1BAK A;  5GOW B;  3ULB A;  3U7D A;  1BWN A;  1EVH A;  2J0M A; 
#chains in the Genus database with same CATH topology
 2D10 A;  1EAZ A;  3QXL A;  3SV1 A;  1PFJ A;  4HB4 B;  5I2M A;  1W1H A;  2COD A;  1UEF A;  4CYE A;  3D8E A;  1J19 A;  2DKQ A;  3NWA A;  3DXE A;  1NVW S;  3PEG A;  3DCX A;  2Y8G A;  4ZRK A;  3A58 A;  1QQG A;  4CSQ A;  1MIX A;  3N7C A;  4DIX A;  4MY6 A;  3CIK A;  2YT0 A;  3BJI A;  1NVU S;  4ZRI A;  3ULC A;  4JGW A;  2YT2 A;  1KZ7 A;  1MPH A;  5C79 A;  5D3X A;  5JHH A;  1MK7 B;  1KZG A;  4F7Z A;  2YS1 A;  2G35 A;  4IOY X;  3HK0 A;  3A8P A;  2DX1 A;  1LW3 A;  2Y7B A;  1BTN A;  2QKM A;  3CXB B;  2KCJ A;  3PSC A;  3TCA A;  2QKL A;  2EJ8 A;  5CM8 A;  2MDX A;  2DN6 A;  2H7E A;  2YT1 A;  4GMX B;  4A6F A;  3VIA A;  1OMW A;  4GN1 A;  4OT1 A;  1P5T A;  4KHB B;  2D9Y A;  3G9W A;  3GYP A;  4HB3 B;  1V5U A;  2CRF A;  2ADZ A;  4GOU A;  4B6H A;  1GC6 A;  3OHM B;  2N0Y A;  3A8Q A;  1TJ6 A;  1F5X A;  4A6H A;  2AEH A;  4MT7 A;  1WG7 A;  2DHI A;  4URX S;  2DA0 A;  4A6K A;  4KAX B;  1QC6 A;  5DIF B;  1WJ1 A;  1EF1 A;  2VKI A;  3U12 A;  2UZS A;  4OSN A;  4PQ0 A;  1XKE A;  3ML4 A;  4A6F B;  2Y8F A;  2RVB B;  3SYX A;  2MFQ A;  5CLQ B;  2W2W A;  2N23 A;  4F7G A;  4URV S;  5I2S A;  2LOZ A;  3OAN A;  4H8S A;  2K8E A;  2VSZ A;  3BIN A;  1U2B A;  3NSU A;  1Y5O A;  4DX8 A;  3GF9 A;  1LB1 A;  5D27 A;  4Y94 A;  5FI1 A;  1NTY A;  3A98 B;  3RCP A;  1ZYI A;  3TFM A;  4HDQ A;  3KRW A;  4XWX A;  4WSF A;  1ZSQ A;  1UPR A;  3IVF A;  2DFK A;  4NSW A;  5LON B;  1OY2 A;  1XOD A;  5L81 A;  4US2 S;  3FSS A;  3PVL A;  3WA0 A;  4HAZ B;  1U5D A;  1X86 A;  2OTX A;  2E2X A;  4NYI S;  1P6S A;  3WYF B;  2DX5 A;  2UZR A;  1UNP A;  1I7A A;  1WGQ A;  2EC1 A;  3PP2 A;  5EFX A;  2Z59 A;  3ZDT A;  1FHO A;  3HSA A;  4DXA B;  5LG4 B;  5C16 A;  2GJY A;  2Z0P A;  2W2X D;  4K2P A;  5JP4 A;  2COF A;  2RUK B;  1FHX A;  5M4Y B;  4MGK E;  1E5W A;  3NW8 A;  2I1K A;  4D6W A;  3KRX A;  2Z0O A;  4NYM S;  3F5R A;  1Y19 B;  4MH0 E;  2CY5 A;  5DHF B;  2RGN B;  3GYO A;  3PZD A;  2K49 A;  4DBB A;  2LUL A;  2COA A;  1ISN A;  2DHJ A;  2FJU B;  2PZ1 A;  2LG1 A;  2DHK A;  1DRO A;  2UVM A;  4HB0 B;  4NYJ S;  1FB8 A;  1U27 A;  2VRW B;  5J3T A;  1U5F A;  5HE2 A;  2DKP A;  1K5D B;  4URU S;  1X1F A;  4MGY E;  2D9V A;  1DBH A;  4US1 S;  4KVG B;  4NY0 A;  1PMS A;  3FEH A;  3VOQ A;  4TKN A;  2KIE A;  2RNR B;  2OQB A;  3ODW A;  2CY4 A;  1M7E A;  1TQZ A;  1NVX S;  4MK0 A;  5KQ4 A;  2YF0 A;  1RJ2 A;  3QBV B;  2COC A;  4GZU A;  1ZM0 A;  3ZVR A;  1KI1 B;  2YSZ A;  4L1R A;  1V5M A;  2V76 A;  1XX0 A;  2ROZ B;  2IYB A;  2R0D A;  4D0O A;  2MKR A;  3QWM A;  4K81 A;  1FAO A;  3DXC A;  1X1G A;  4GYV A;  2EMT A;  3X23 A;  5C5B A;  4Z2N A;  3O96 A;  2MWN B;  2R09 A;  4F7H A;  5J3Y A;  1BKD S;  3NWF A;  2YRY A;  1Z87 A;  5CM9 A;  1X05 A;  2Z14 A;  4EMO A;  4MGZ E;  2I1J A;  3PVU A;  4P7I A;  2P8V A;  2GCJ A;  3PG7 A;  4F7U P;  4BBK A;  2R2Y A;  1H10 A;  2D9X A;  3FVC A;  1IRS A;  3V5W A;  2NZ8 B;  1N3H A;  1DYN A;  2IFS A;  5D3Y A;  5HE0 A;  4HDO A;  4ZRJ A;  2ZPY A;  4CHJ A;  3T06 A;  4TYZ A;  5C5B B;  1V61 A;  1Q67 A;  3SO6 A;  5C6R A;  1H4R A;  2ELB A;  4QXA B;  2GCL A;  2L1C A;  2AL6 A;  1UNQ A;  1GC7 A;  3M1I B;  1M7R A;  2YS3 A;  3SUZ A;  4GNK B;  1UNR A;  2I5C A;  5J3Q A;  3U8Z A;  1ZC3 B;  2D4Q A;  3ODO A;  3TVV A;  3DXD A;  1AQC A;  4QJ4 B;  3B77 A;  3F0W A;  5DI9 B;  2DYQ A;  2RLO A;  1XD2 C;  4URW S;  4Z2M B;  3NWD A;  4KHO A;  4L9M A;  2KIG A;  1UPQ A;  3LJU X;  2J0J A;  2GUM A;  4HSI A;  1MK9 B;  2Q13 A;  2KUQ A;  3KZ1 A;  1FGY A;  2H7D A;  2BCJ A;  1T77 A;  2J0K A;  2Z4D A;  4HAW B;  4WJ7 A;  4GXB A;  4DX9 0;  1P3R A;  1FHW A;  1WJM A;  5DHA B;  3TO1 A;  4D0N B;  4HAU B;  1J0W A;  1I2H A;  2II0 A;  1V89 A;  3AJ4 A;  5CLL B;  2D11 A;  4IAP A;  1MIZ B;  4A5K A;  4GPT B;  4HAY B;  3ODX A;  1B55 A;  3MDB C;  2NBV A;  2Z13 A;  5JHG A;  4IFS A;  3P6A A;  2NMB A;  1MAI A;  2GS0 A;  2I5F A;  1ZVR A;  2IJE S;  1K5G B;  4KHA A;  2XQN M;  2X18 A;  4EJN A;  1NU2 A;  2J59 M;  2BYV E;  4KHB A;  2ROV A;  1DDM A;  2Z0Q A;  4C0A A;  2K2J A;  3TW1 A;  5HE3 A;  2HE7 A;  3T6G A;  2KGX B;  2JP2 A;  1TXD A;  1MKE A;  2DTC A;  4K17 A;  5IRS A;  3T6A A;  3D8F A;  5LOP B;  1DDW A;  4HHV A;  2M14 A;  4L6E A;  3AU4 A;  1NVV S;  5D3W A;  2LYD A;  3HQC A;  1FOE A;  2KR9 A;  3AU5 A;  2KUP A;  4MGI E;  1DDV A;  2EMS A;  2D9Z A;  1NTV A;  1SHC A;  1WI1 A;  5D3V A;  1XCG A;  2DLW A;  3HW2 B;  1BTK A;  1U5E A;  4EKU A;  3KSY A;  2YVC A;  2LOX A;  3PVW A;  3HIE A;  1SGH A;  2D2Q A;  4HAT B;  4URZ S;  5FI0 A;  2K00 A;  2FJL A;  4YON A;  5DH9 B;  2L2I A;  4HAX B;  4HB2 B;  1FGZ A;  3D8D A;  2ZKM X;  1WGU A;  3SNH A;  2CAY A;  2W2X C;  1X11 A;  2RRF A;  1WVH A;  4CHM A;  3UZT A;  2K2U A;  1V5P A;  2P0H A;  4QJ5 B;  4QJ3 B;  2RSG A;  3QIJ A;  3P7Z A;  1AWE A;  2DYN A;  2P0F A;  1OQN A;  2KR0 A;  4US0 S;  5JLJ B;  3EO2 A;  1GG3 A;  5KQ1 A;  2D9W A;  5HE1 A;  3MPX A;  4YL8 A;  1XR0 B;  3FM8 C;  2M38 A;  2YS5 A;  2LKO A;  5KCV A;  1NI2 A;  4PNK A;  1XD4 A;  4K2O A;  1U5G A;  1BY1 A;  1RRP B;  2P0D A;  2ELA A;  1PLS A;  3KY9 A;  1W1G A;  1ZC4 B;  3CF6 E;  1V88 A;  1EGX A;  3JV3 A;  1MI1 A;  4GMV A;  4HAV B;  1W1D A;  4URY S;  4WVF B;  1U29 A;  2HTH B;  1BAK A;  5GOW B;  3ULB A;  3U7D A;  1BWN A;  1EVH A;  2J0M A; 
#chains in the Genus database with same CATH homology
 2D10 A;  1EAZ A;  3QXL A;  3SV1 A;  1PFJ A;  4HB4 B;  1W1H A;  2COD A;  1UEF A;  4CYE A;  3D8E A;  1J19 A;  2DKQ A;  3DXE A;  1NVW S;  3PEG A;  2Y8G A;  4ZRK A;  1QQG A;  1MIX A;  3N7C A;  4MY6 A;  3CIK A;  2YT0 A;  3BJI A;  1NVU S;  4ZRI A;  3ULC A;  4JGW A;  1KZ7 A;  1MPH A;  5C79 A;  5D3X A;  5JHH A;  1MK7 B;  1KZG A;  4F7Z A;  2YS1 A;  2G35 A;  4IOY X;  3HK0 A;  3A8P A;  2DX1 A;  1LW3 A;  2Y7B A;  1BTN A;  2QKM A;  3CXB B;  2KCJ A;  3PSC A;  3TCA A;  2QKL A;  2EJ8 A;  5CM8 A;  2MDX A;  2DN6 A;  2H7E A;  2YT1 A;  4GMX B;  4A6F A;  3VIA A;  1OMW A;  4GN1 A;  1P5T A;  4KHB B;  2D9Y A;  3G9W A;  3GYP A;  4HB3 B;  1V5U A;  2CRF A;  2ADZ A;  4GOU A;  4B6H A;  1GC6 A;  2N0Y A;  3A8Q A;  1TJ6 A;  1F5X A;  4A6H A;  2AEH A;  4MT7 A;  1WG7 A;  2DHI A;  4URX S;  2DA0 A;  4A6K A;  4KAX B;  1QC6 A;  5DIF B;  1WJ1 A;  1EF1 A;  2VKI A;  2UZS A;  4A6F B;  4PQ0 A;  1XKE A;  3ML4 A;  2Y8F A;  2RVB B;  3SYX A;  2MFQ A;  5CLQ B;  2W2W A;  2N23 A;  4F7G A;  4URV S;  2LOZ A;  3OAN A;  4H8S A;  2VSZ A;  3BIN A;  1U2B A;  3NSU A;  1Y5O A;  4DX8 A;  3GF9 A;  1LB1 A;  5D27 A;  4Y94 A;  5FI1 A;  1NTY A;  3A98 B;  3RCP A;  3TFM A;  4HDQ A;  3KRW A;  4XWX A;  4WSF A;  1ZSQ A;  1UPR A;  3IVF A;  2DFK A;  4NSW A;  5LON B;  1OY2 A;  1XOD A;  5L81 A;  4US2 S;  3FSS A;  3PVL A;  3WA0 A;  4HAZ B;  1U5D A;  1X86 A;  2OTX A;  2E2X A;  4NYI S;  1P6S A;  3WYF B;  2DX5 A;  2UZR A;  1UNP A;  1I7A A;  1WGQ A;  2EC1 A;  3PP2 A;  5EFX A;  3ZDT A;  1FHO A;  4DXA B;  5C16 A;  2GJY A;  2Z0P A;  2W2X D;  4K2P A;  5JP4 A;  2COF A;  2RUK B;  1FHX A;  4MGK E;  1E5W A;  2I1K A;  3KRX A;  2Z0O A;  4NYM S;  3F5R A;  1Y19 B;  4MH0 E;  2CY5 A;  5DHF B;  2RGN B;  3GYO A;  3PZD A;  4DBB A;  2LUL A;  2COA A;  1ISN A;  2DHJ A;  2PZ1 A;  2LG1 A;  2DHK A;  1DRO A;  2UVM A;  4HB0 B;  4NYJ S;  1FB8 A;  1U27 A;  2VRW B;  5J3T A;  1U5F A;  5HE2 A;  2DKP A;  1K5D B;  4URU S;  1X1F A;  4MGY E;  2D9V A;  1DBH A;  4US1 S;  4KVG B;  4NY0 A;  1PMS A;  3FEH A;  3VOQ A;  4TKN A;  2RNR B;  2OQB A;  3ODW A;  2CY4 A;  1M7E A;  1TQZ A;  1NVX S;  4MK0 A;  5KQ4 A;  2YF0 A;  1RJ2 A;  3QBV B;  2COC A;  4GZU A;  1ZM0 A;  3ZVR A;  1KI1 B;  2YSZ A;  1V5M A;  2V76 A;  1XX0 A;  2ROZ B;  2IYB A;  2R0D A;  4D0O A;  2MKR A;  3QWM A;  4K81 A;  1FAO A;  3DXC A;  1X1G A;  4GYV A;  2EMT A;  3X23 A;  5C5B A;  4Z2N A;  3O96 A;  2MWN B;  2R09 A;  4F7H A;  5J3Y A;  1BKD S;  2YRY A;  1Z87 A;  5CM9 A;  1X05 A;  4EMO A;  4MGZ E;  2I1J A;  3PVU A;  4P7I A;  2P8V A;  2GCJ A;  3PG7 A;  4F7U P;  4BBK A;  1H10 A;  2D9X A;  1IRS A;  3V5W A;  2NZ8 B;  1N3H A;  1DYN A;  2IFS A;  5D3Y A;  5HE0 A;  4HDO A;  4ZRJ A;  2ZPY A;  4CHJ A;  3T06 A;  4TYZ A;  5C5B B;  1V61 A;  1Q67 A;  3SO6 A;  5C6R A;  1H4R A;  2ELB A;  2GCL A;  2L1C A;  2AL6 A;  1UNQ A;  1GC7 A;  3M1I B;  1M7R A;  2YS3 A;  3SUZ A;  1UNR A;  2I5C A;  5J3Q A;  3U8Z A;  1ZC3 B;  2D4Q A;  3ODO A;  3TVV A;  3DXD A;  1AQC A;  3F0W A;  5DI9 B;  2DYQ A;  2RLO A;  1XD2 C;  4URW S;  4Z2M B;  4KHO A;  4L9M A;  1UPQ A;  3LJU X;  2J0J A;  1MK9 B;  2Q13 A;  3KZ1 A;  1FGY A;  2H7D A;  2BCJ A;  2J0K A;  4HAW B;  4WJ7 A;  4GXB A;  4DX9 0;  1P3R A;  1FHW A;  1WJM A;  5DHA B;  3TO1 A;  4D0N B;  4HAU B;  1J0W A;  1I2H A;  2II0 A;  1V89 A;  3AJ4 A;  5CLL B;  2D11 A;  4IAP A;  1MIZ B;  4A5K A;  4GPT B;  4HAY B;  3ODX A;  1B55 A;  3MDB C;  5JHG A;  4IFS A;  3P6A A;  2NMB A;  1MAI A;  2GS0 A;  2I5F A;  1ZVR A;  2IJE S;  1K5G B;  4KHA A;  2XQN M;  2X18 A;  4EJN A;  1NU2 A;  2J59 M;  2BYV E;  2ROV A;  1DDM A;  2Z0Q A;  4C0A A;  2K2J A;  3TW1 A;  5HE3 A;  2HE7 A;  3T6G A;  2KGX B;  2JP2 A;  1TXD A;  1MKE A;  2DTC A;  4K17 A;  3T6A A;  3D8F A;  5LOP B;  1DDW A;  4HHV A;  2M14 A;  4L6E A;  3AU4 A;  1NVV S;  5D3W A;  2LYD A;  3HQC A;  1FOE A;  2KR9 A;  3AU5 A;  2KUP A;  4MGI E;  1DDV A;  2EMS A;  2D9Z A;  1NTV A;  1SHC A;  1WI1 A;  5D3V A;  1XCG A;  2DLW A;  3HW2 B;  1BTK A;  1U5E A;  4EKU A;  3KSY A;  2YVC A;  2LOX A;  3PVW A;  1SGH A;  2D2Q A;  4HAT B;  4URZ S;  5FI0 A;  2K00 A;  2FJL A;  4YON A;  5DH9 B;  2L2I A;  4HAX B;  4HB2 B;  1FGZ A;  3D8D A;  1WGU A;  3SNH A;  2CAY A;  2W2X C;  1X11 A;  1WVH A;  4CHM A;  3UZT A;  2K2U A;  1V5P A;  2P0H A;  2RSG A;  3QIJ A;  3P7Z A;  1AWE A;  2DYN A;  2P0F A;  1OQN A;  4US0 S;  5JLJ B;  3EO2 A;  1GG3 A;  5KQ1 A;  2D9W A;  5HE1 A;  3MPX A;  4YL8 A;  1XR0 B;  3FM8 C;  2M38 A;  2YS5 A;  2LKO A;  5KCV A;  1NI2 A;  4PNK A;  1XD4 A;  4K2O A;  1U5G A;  1BY1 A;  1RRP B;  2P0D A;  2ELA A;  1PLS A;  3KY9 A;  1W1G A;  1ZC4 B;  3CF6 E;  1V88 A;  1EGX A;  3JV3 A;  4GMV A;  4HAV B;  1W1D A;  4URY S;  4WVF B;  1U29 A;  2HTH B;  1BAK A;  5GOW B;  3ULB A;  3U7D A;  1BWN A;  1EVH A;  2J0M A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1XD4A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations