4LQYA

Crystal structure of human enpp4 with amp
Total Genus 127
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
Knots found
sequence length
379
structure length
379
Chain Sequence
LPPKLLLVSFDGFRADYLKNYEFPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDAVTKKHFSDSNDKDPFWWNEAVPIWVTNQLQENRSSAAAMWPGTDVPIHDTISSYFMNYNSSVSFEERLNNITMWLNNSNPPVTFATLYWEEPDASGHKYGPEDKENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSYYTLIDLSPVAAILPKINRTEVYNKLKNCSPHMNVYLKEDIPNRFYYQHNDRIQPIILVADEGWTIVLNESSQKLGDHGYDNSLPSMHPFLAAHGPAFHKGYKHSTINIVDIYPMMCHILGLKPHPNNGTFGHTKCLLVDQWCI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Molecular basis of purinergic signal metabolism by ectonucleotide pyrophosphatase/phosphodiesterases 4 and 1 and implications in stroke.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Bis(5'-adenosyl)-triphosphatase ENPP4
total genus 127
structure length 379
sequence length 379
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.6.1.29: Bis(5'-adenosyl)-triphosphatase.
pdb deposition date 2013-07-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.180 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Gyrase A; domain 2 4lqyA02
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4lqyA01
3UO0A 2W5SA 3LXQA 4LRFA 1AJAA 3MK1A 4LR9A 4YR1A 5INHA 4ZG6A 5LQQA 2GA3A 3ED4A 4CXKA 4UPHA 3M8YA 2XR9A 2W5QA 4CXSA 1K7HA 1E1ZP 3B5QA 3NVLA 4GTZA 4MY4A 1URBA 4MHXA 2W5VA 4N7TA 2W8DA 3NKQA 1ELYA 5DLWA 4UOOA 3CMRA 2D1GA 5LIAA 1ELZA 2IUCB 5TJ3A 1ZEFA 3IDDA 3BDHA 5LRNA 1KHKA 5IJSA 4UPIA 1HQAA 5EGHA 1P49A 1URAA 4KJDA 5C66A 1KH4A 4UPKA 1EW2A 2IUCA 2ANHA 4GTXA 1FSUA 3WAWA 5KXAA 1N2KA 2GLQA 1AUKA 4LR8A 4KJGA 5K4PA 4CYRA 4FDJA 2GSUA 1EW8A 1N2LA 4GTWA 4LREA 4QAXA 2G9YA 1ZEBA 1Y6VA 1KH9A 1AJCA 4GTYA 2QZUA 3UN2A 3NKPA 3A52A 4UOPA 2W5XA 4MIVA 3IGYB 1SHQA 3T01A 3E2DA 3M8WA 1ALJA 3KD8A 1B8JA 1ELXA 2W5RA 1ED9A 1KH5A 3NKMA 3DPCA 3UNYA 4LR2A 4ZG7A 1ANJA 4CXUA 4FDIA 3T02A 1KHJA 2W5WA 5DLTA 2IFYA 1ED8A 2XRGA 4LR7A 5GRRA 3NKNA 1ZEDA 3TWZA 3UN3A 3MK2A 4LRCA 5LRMA 2RH6A 1O98A 4LRBA 1EQJA 3SZZA 1KHLA 5EGEA 3OT9A 1O99A 3M8ZA 1E33P 1SHNA 3Q3QA 3WBHA 1ALKA 4UPLA 2W8SA 5HRTA 2W5TA 4ZG9A 3M7VA 1EJJA 3BDGB 4KAYA 3DYCA 3TG0A 1EW9A 1KHNA 3WAYA 5L0EA 5GOVA 3TX0A 5IJQA 4LQYA 3NKRA 3T00A 4B56A 1ALIA 5AJ9A 4ZGAA 1Y7AA 2ZKTA 1EI6A 3WAVA 1ALHA 4KAVA 3NKOA 1E2SP 1E3CP 4NWXA 4KM4A 1KH7A 4UORA 1ANIA 5DLVA 3BDGA 2X98A 4LRAA 2GSNA 1AJDA 4CYSA 3IGZB 1HJKA 4TN0A 2GSOA 4LRDA 3WAXA 3SZYA 1HDHA 4NWJA 5L0KA 3MK0A 3UN5A 3BDFA 1AJBA 5L0BA 2VQRA
chains in the Genus database with same CATH superfamily
3GSIA 4KMDA 4C2MK 1WORA 3PO3C 2WB1D 3GTQK 3S17C 1TWFA 1G51A 3S16K 4CXKA 2R93C 3GTMC 1PJ5A 5CHPA 1B4AA 4BLBA 1TWAA 3HOVK 4N7TA 2W8DA 3NKQA 4MQ9A 5TMFA 4A3BK 5DLWA 5LIAA 5C44K 5C4XK 1Y1WK 2JA8C 1Y1VK 1TWHA 4A3MK 5CJ9A 3LPXA 1O2AA 3IDDA 1I50A 3N0CA 3BDHA 3PO3K 5IJSA 3S17K 4YFKA 4KJDA 4DDQA 2R93K 4C3JK 3GTMK 4X6AC 1KH4A 2IUCA 1FSUA 1AUKA 1K83C 2WAQD 4BXXC 4BBRC 4GFQA 4NOIA 4MEYA 4XLNA 3RZDC 4Q4ZA 1KH9A 1HI9A 1R9TA 2JA8K 2A6HA 1DD5A 2NVYA 3S1MC 4UOPA 2W5XA 1WOPA 1INNA 1O27A 1J98A 3E2DA 3M8WA 5C4JC 2O5JA 1IQ0A 4X6AK 3GTJC 3PO2C 3DPCA 3UNYA 4LR2A 5IOTA 2JA5A 3ADAC 1ANJA 4CXUA 1IS1A 1K83K 2JA6C 3OPFA 4BXXK 2IFYA 1ED8A 4BBRK 5GRRA 5M5WK 3NKNA 1ZEDA 4QIWL 3TWZA 3RZDK 3MK2A 3L4JA 4Q5SA 1I6VA 4P9SA 5EGEA 2E2HC 3S1MK 1VJEA 4YG2A 5IP9C 2W8SA 1I3QA 2A69A 3HKZD 4GTLA 1F9NA 3M7VA 1YCLA 2XCRB 1BJTA 1TWGA 5C4JK 4KN7A 3FHZA 5L0EA 1EK8A 1EH1A 3GTJK 1WQHA 3PO2K 2VUMA 3T00A 4B56A 3AH5A 1XZPA 4A3GC 1EI6A 2YU9C 4GTEA 2JA6K 5E68A 3GTOA 1F93A 4LK1A 3IGZB 3RZOC 1HJKA 1PJ6A 1WCMA 3S1RC 3GTKC 5IP9K 4LRDA 3WAXA 4NWJA 5L0KA 1V5VA 3CQZC 3MK0A 1O2BA 1JQWA 3BDFA 3FOEA 1WSVA 5L0BA 5M3MK 1IL2A 3GEHA 4A3GK 1AJAA 5LQQA 2GA3A 4O2DA 2R93A 4UPHA 3FKIC 4G0VA 3M8YA 3GTPC 3BUEA 3RZOK 4OIPA 1K7HA 1YX2A 2WB1L 1E1ZP 3GTGC 1XXBA 3B5QA 3S1RK 3S1QC 3GTKK 4MY4A 4OINA 4MHXA 3AQOA 3CQZK 4GTAA 2PA8D 4J3NA 4UOOA 3CMRA 2D1GA 3AD7C 4GTBA 1ELZA 4A93K 4RMFA 3H3VL 2IUCB 2CFAA 3HOWC 3S14C 5M3FK 5LRNA 1KHKA 4UPIA 3ERED 3TTGA 1P49A 3FKIK 2ZFZA 5C66A 1WIHA 3GTPK 4UPKA 4GTXA 3DXJA 1N2KA 1UV7A 3GTGK 4C3JC 3S1QK 4KMUA 3QX3A 4GTDA 2GSUA 1EW8A 4GTWA 4QAXA 2PMZD 2NVXC 3GTLC 3HOUC 1AJCA 3N0BA 1O25A 2P8TA 3A52A 3EQLA 3HOWK 3S14K 4OIOA 4MIVA 2A6EA 4Y7NC 4GZYA 4KC6A 2JA7A 1VLOA 1ALJA 1DCPA 2W5RA 1KH5A 3HXAA 2BE5A 2E2IC 1KHJA 4A3CC 2CW0A 4KB4A 2R92C 2ZUEA 2B63A 1ZBSA 3UN3A 2NVXK 3BP3A 3GTLK 3HOUK 2Y3PA 4LRCA 5LRMA 4C3IC 1DCHA 3CAGA 4XSXA 4A3JC 2E2HA 4WJ3M 3Q3QA 3OT9A 1ZXOA 4G0WA 1ALKA 1XZPB 4UPLA 5D4DA 3OEPA 1WSRA 5HRTA 4Y7NK 2PHCB 4BY7C 2V6UA 5IOQA 2PPBA 4KAYA 3TG0A 3WAYA 3NUHA 1EQRA 4JK1A 1WOOA 1F7VA 1YNNA 4P5AA 2YU9A 2E2IK 1Y7AA 4KATA 3LAPA 5AJ9A 3IPJA 4PAAA 4A3CK 1TWFC 1ALHA 3NKOA 1E2SP 4KM4A 2R92K 5IYDC 5DLVA 4OIRA 3TFJA 1AJDA 4CYSA 4C3IK 4A3JK 1TWAC 3M4OC 3AD8C 3WODA 4M1XA 1SFOA 1WQGA 1HDHA 4BY7K 1EFWA 2R7ZA 3UN5A 1J6VA 1TWHC 3L4KA 4OIQA 4XCHA 4LJZA 1I50C 3UO0A 1X31C 3K7AC 4LR9A 1TWFK 4FM9A 4YR1A 5INHA 4ILDA 5IYDK 3ED4A 3GTQA 2XR9A 2GAGC 1IW7A 3N3YA 3GTGA 1TWAK 4A3IC 3NVLA 3M4OK 2CFAB 4GTZA 1URBA 1ZYRA 2W5VA 4LLGA 3JSTA 1L0WA 5C3EC 1R9TC 1TWHK 2NVYC 4AYBD 3GDZA 2W7VA 1Y1WA 1I50K 4A3DC 3V4GA 1Y1VA 4A93C 3G4AA 1ZEFA 3K7AK 1XXCA 4QIWD 5EGHA 5L46A 3HOZC 2JA5C 4KN4A 4PABA 3TFHA 1J6WA 1O2FB 1O26A 4KM8A 4A3KC 1EW2A 3WAWA 3S0XA 2Y0SD 3GTMA 3S15C 4A3IK 1JVIA 1J6XA 4CYRA 4FDJA 4LREA 5C3EK 1R9TK 4BLAA 1Y6VA 4GTYA 2QZUA 2EBBA 2NVYK 5FLMC 1I3QC 4A3DK 3UN2A 3NKPA 1BS2A 2E2JC 2XCQA 3IGYB 1XXAA 1SHQA 3T01A 4BY1C 1XPPA 5M5XK 2VUMC 1TWCC 3HOZK 2JA5K 1ED9A 2NVTC 2JH3A 4A3KK 3GEEA 4ZG7A 1IE0A 5FJ8K 3S15K 4BBSC 3VA7A 4FDIA 5IP7C 1HQMA 3GEIA 2W5WA 2R92A 4G7HA 1K83A 3GTOC 5TMCA 4XSZA 4G7ZA 2GAHC 4QJVA 3HOYC 4GT9A 4BKWA 1O98A 4G7OA 4A3EK 3SZZA 1EQJA 1WCMC 4GTFA 5FLMK 1WOSA 1I3QK 1E33P 2WAQL 2E2JK 1TWGK 4ZG9A 4BY1K 1F7UA 2VUMK 3DYCA 1TWCK 1EW9A 1KHNA 5GOVA 2NVTK 3TX0A 1USOA 2ZUFA 4LQYA 5IJQA 1VH2A 3FOFA 1ALIA 3GTJA 4BBSK 1BDFA 1SMYA 2ZKTA 5IP7K 4UORA 4NWXA 1E3CP 4AH6A 4KM9A 3GTOK 1C0AA 2JA6A 3BDGA 4G0UA 3AD9C 3HOYK 2X98A 2GSNA 4LRAA 3H3VD 1WCMK 3A8IA 4KMAA 2GSOA 2P5MA 3SZYA 1XZQA 4A3LC 1WQFA 4KARA 1JOEA 3H0GC 1AJBA 3S2HC 2VQRA 4C45A 5IYBC 4LK0A 2W5SA 3LXQA 4LRFA 3MK1A 5IYCC 3HKZL 4ZG6A 1O29A 2W5QA 4CXSA 3BP8C 2A68A 4P5BA 3S1NC 4WJ4A 4KDDA 3GTKA 4A3LK 3AQPA 1ELYA 2V6TA 3H0GK 3CQZA 3S2HK 1RU0A 1I6HC 3A8JA 5IYBK 5TJ3A 2JA7C 5IYCK 4AYBL 2D6FC 4ZH4A 2O5IA 2KWAA 1HQAA 1URAA 5JFEA 1BGWA 4A3FC 3FKIA 2ANHA 5KXAA 1ZQ1C 2GLQA 1AB4A 3S1NK 3GTPA 3TFIA 3M3YC 4LR8A 1VGXA 4KB2A 4KJGA 1KQ4A 2B63C 4C3HC 5K4PA 1N2LA 2G9YA 2Y0SL 1ZEBA 4KAWX 3I4NC 1USMA 1I6HK 4Y52C 2JA7K 3HOXC 2PA8L 4XLPA 1TWCA 5IORA 4QJVB 3KD8A 4KASA 1B8JA 1ELXA 3LAJA 1GE9A 3NKMA 2RGRA 2NVQC 4A3FK 3M3YK 3T02A 4YFNA 2B63K 3GIRA 4C3HK 5DLTA 3S2DC 2XRGA 4LR7A 4MEXA 2E2HK 3I4NK 2RH6A 3I4MC 4LRBA 2NVXA 3GTLA 1KHLA 1SFOC 4Y52K 1O99A 3M8ZA 1SHNA 3WBHA 3A8KA 2XCOA 1ISEA 2R7ZC 4WILA 4A3EC 2W5TA 1PJ7A 1O24A 3HOXK 2FQOA 1EJJA 2PMZL 3BDGB 3G4CA 1TWGC 5IOSA 2YU9K 2NVQK 4GTCA 1O28A 3NKRA 1YNJA 3OREA 4ZGAA 3WAVA 4FZBA 4C2MC 4KAVA 1ANIA 3S2DK 2E2IA 1XZQB 1KH7A 4YFXA 5M5YK 3GTQC 3S16C 4KMHA 1VRQC 3MMLB 1ZVUA 3I4MK 1DCOA 1IBAA 1SFOK 4LOWA 1B4BA 2V6SA 4TN0A 2R7ZK 3HOVC 2FQTA 3H0GA 4A3BC 5JVOA 5C44C 5C4XC 5HL8A 1Y1WC 1Y1VC 4A3MC
chains in the Genus database with same CATH topology
4KMDA 1TWFA 4CXKA 5CHPA 1B4AA 4BLBA 1TWAA 4N7TA 2W8DA 3NKQA 5DLWA 5LIAA 1TWHA 5CJ9A 3LPXA 1O2AA 3IDDA 1I50A 3N0CA 3BDHA 5IJSA 4KJDA 4DDQA 1KH4A 2IUCA 1FSUA 1AUKA 4GFQA 1KH9A 1R9TA 1DD5A 2NVYA 4UOPA 2W5XA 1O27A 3E2DA 3M8WA 3DPCA 3UNYA 4LR2A 5IOTA 2JA5A 1ANJA 4CXUA 1IS1A 3OPFA 2IFYA 1ED8A 5GRRA 3NKNA 1ZEDA 3TWZA 3MK2A 3L4JA 5EGEA 2W8SA 1I3QA 4GTLA 1F9NA 3M7VA 2XCRB 1BJTA 1TWGA 3FHZA 5L0EA 1EK8A 1EH1A 2VUMA 1WQHA 3T00A 4B56A 3AH5A 1EI6A 4GTEA 3GTOA 3IGZB 1HJKA 1WCMA 4LRDA 3WAXA 4NWJA 5L0KA 3MK0A 1O2BA 3BDFA 3FOEA 5L0BA 1AJAA 5LQQA 2GA3A 2R93A 4UPHA 4G0VA 3M8YA 3BUEA 1K7HA 1E1ZP 3B5QA 1XXBA 4MY4A 4MHXA 3AQOA 4GTAA 4J3NA 4UOOA 3CMRA 2D1GA 4GTBA 1ELZA 2IUCB 2CFAA 5LRNA 1KHKA 4UPIA 3ERED 1P49A 2ZFZA 5C66A 4UPKA 1WIHA 4GTXA 1N2KA 4C3JC 3QX3A 4GTDA 2GSUA 1EW8A 4GTWA 4QAXA 1AJCA 3N0BA 1O25A 3A52A 4MIVA 4KC6A 2JA7A 1ALJA 2W5RA 1KH5A 1KHJA 4KB4A 2B63A 1ZBSA 3UN3A 4LRCA 2Y3PA 5LRMA 4C3IC 3CAGA 2E2HA 3Q3QA 3OT9A 1ZXOA 4G0WA 1ALKA 4UPLA 3OEPA 5HRTA 2PHCB 5IOQA 4KAYA 3TG0A 3WAYA 3NUHA 5AJ9A 2YU9A 4P5AA 1Y7AA 4KATA 3LAPA 1ALHA 3NKOA 1E2SP 4KM4A 5DLVA 1AJDA 4CYSA 1SFOA 4M1XA 1WQGA 1HDHA 2R7ZA 3UN5A 3L4KA 3UO0A 4LR9A 4FM9A 4YR1A 5INHA 4ILDA 3ED4A 3GTQA 2XR9A 3N3YA 3GTGA 3NVLA 2CFAB 4GTZA 1URBA 2W5VA 1Y1WA 3V4GA 1Y1VA 1ZEFA 3G4AA 1XXCA 5EGHA 1O26A 4KM8A 1EW2A 3WAWA 3S0XA 3GTMA 4CYRA 4FDJA 4LREA 4BLAA 1Y6VA 4GTYA 2QZUA 3UN2A 3NKPA 2XCQA 3IGYB 1XXAA 1SHQA 3T01A 1ED9A 2JH3A 4ZG7A 3VA7A 4FDIA 2W5WA 2R92A 1K83A 4GT9A 4BKWA 1O98A 1EQJA 3SZZA 4GTFA 1E33P 4ZG9A 3DYCA 1EW9A 1KHNA 5GOVA 3TX0A 5IJQA 4LQYA 3FOFA 1ALIA 3GTJA 2ZKTA 4UORA 4NWXA 1E3CP 4KM9A 2JA6A 3BDGA 4G0UA 2X98A 4LRAA 2GSNA 4KMAA 2GSOA 2P5MA 3SZYA 1WQFA 4KARA 1AJBA 2VQRA 2W5SA 3LXQA 4LRFA 3MK1A 4ZG6A 1O29A 2W5QA 4CXSA 4P5BA 4KDDA 3GTKA 3AQPA 1ELYA 3CQZA 5TJ3A 2KWAA 1HQAA 1URAA 5JFEA 1BGWA 3FKIA 2ANHA 5KXAA 2GLQA 1AB4A 3GTPA 4LR8A 4KB2A 4KJGA 1KQ4A 4C3HC 5K4PA 1N2LA 2G9YA 1ZEBA 4KAWX 1TWCA 5IORA 3KD8A 4KASA 1B8JA 1ELXA 3LAJA 1GE9A 3NKMA 2RGRA 3T02A 5DLTA 2XRGA 4LR7A 2RH6A 4LRBA 2NVXA 3GTLA 1KHLA 1O99A 3M8ZA 1SHNA 3WBHA 2XCOA 1ISEA 2W5TA 1O24A 1EJJA 3BDGB 3G4CA 5IOSA 4GTCA 1O28A 3NKRA 3OREA 4ZGAA 3WAVA 4FZBA 4C2MC 4KAVA 1ANIA 2E2IA 1KH7A 4KMHA 3MMLB 1ZVUA 1B4BA 4TN0A 3H0GA 5JVOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UO0 A;  2W5S A;  3LXQ A;  4LRF A;  1AJA A;  3MK1 A;  4LR9 A;  4YR1 A;  5INH A;  4ZG6 A;  5LQQ A;  2GA3 A;  3ED4 A;  4CXK A;  4UPH A;  3M8Y A;  2XR9 A;  2W5Q A;  4CXS A;  1K7H A;  1E1Z P;  3B5Q A;  3NVL A;  4GTZ A;  4MY4 A;  1URB A;  4MHX A;  2W5V A;  4N7T A;  2W8D A;  3NKQ A;  1ELY A;  5DLW A;  4UOO A;  3CMR A;  2D1G A;  5LIA A;  1ELZ A;  2IUC B;  5TJ3 A;  1ZEF A;  3IDD A;  3BDH A;  5LRN A;  1KHK A;  5IJS A;  4UPI A;  1HQA A;  5EGH A;  1P49 A;  1URA A;  4KJD A;  5C66 A;  1KH4 A;  4UPK A;  1EW2 A;  2IUC A;  2ANH A;  4GTX A;  1FSU A;  3WAW A;  5KXA A;  1N2K A;  2GLQ A;  1AUK A;  4LR8 A;  4KJG A;  5K4P A;  4CYR A;  4FDJ A;  2GSU A;  1EW8 A;  1N2L A;  4GTW A;  4LRE A;  4QAX A;  2G9Y A;  1ZEB A;  1Y6V A;  1KH9 A;  1AJC A;  4GTY A;  2QZU A;  3UN2 A;  3NKP A;  3A52 A;  4UOP A;  2W5X A;  4MIV A;  3IGY B;  1SHQ A;  3T01 A;  3E2D A;  3M8W A;  1ALJ A;  3KD8 A;  1B8J A;  1ELX A;  2W5R A;  1ED9 A;  1KH5 A;  3NKM A;  3DPC A;  3UNY A;  4LR2 A;  4ZG7 A;  1ANJ A;  4CXU A;  4FDI A;  3T02 A;  1KHJ A;  2W5W A;  5DLT A;  2IFY A;  1ED8 A;  2XRG A;  4LR7 A;  5GRR A;  3NKN A;  1ZED A;  3TWZ A;  3UN3 A;  3MK2 A;  4LRC A;  5LRM A;  2RH6 A;  1O98 A;  4LRB A;  1EQJ A;  3SZZ A;  1KHL A;  5EGE A;  3OT9 A;  1O99 A;  3M8Z A;  1E33 P;  1SHN A;  3Q3Q A;  3WBH A;  1ALK A;  4UPL A;  2W8S A;  5HRT A;  2W5T A;  4ZG9 A;  3M7V A;  1EJJ A;  3BDG B;  4KAY A;  3DYC A;  3TG0 A;  1EW9 A;  1KHN A;  3WAY A;  5L0E A;  5GOV A;  3TX0 A;  5IJQ A;  4LQY A;  3NKR A;  3T00 A;  4B56 A;  1ALI A;  5AJ9 A;  4ZGA A;  1Y7A A;  2ZKT A;  1EI6 A;  3WAV A;  1ALH A;  4KAV A;  3NKO A;  1E2S P;  1E3C P;  4NWX A;  4KM4 A;  1KH7 A;  4UOR A;  1ANI A;  5DLV A;  3BDG A;  2X98 A;  4LRA A;  2GSN A;  1AJD A;  4CYS A;  3IGZ B;  1HJK A;  4TN0 A;  2GSO A;  4LRD A;  3WAX A;  3SZY A;  1HDH A;  4NWJ A;  5L0K A;  3MK0 A;  3UN5 A;  3BDF A;  1AJB A;  5L0B A;  2VQR A; 
#chains in the Genus database with same CATH topology
 3GSI A;  4KMD A;  4C2M K;  1WOR A;  3PO3 C;  2WB1 D;  3GTQ K;  3S17 C;  1TWF A;  1G51 A;  3S16 K;  4CXK A;  2R93 C;  3GTM C;  1PJ5 A;  5CHP A;  1B4A A;  4BLB A;  1TWA A;  3HOV K;  4N7T A;  2W8D A;  3NKQ A;  4MQ9 A;  5TMF A;  4A3B K;  5DLW A;  5LIA A;  5C44 K;  5C4X K;  1Y1W K;  2JA8 C;  1Y1V K;  1TWH A;  4A3M K;  5CJ9 A;  3LPX A;  1O2A A;  3IDD A;  1I50 A;  3N0C A;  3BDH A;  3PO3 K;  5IJS A;  3S17 K;  4YFK A;  4KJD A;  4DDQ A;  2R93 K;  4C3J K;  3GTM K;  4X6A C;  1KH4 A;  2IUC A;  1FSU A;  1AUK A;  1K83 C;  2WAQ D;  4BXX C;  4BBR C;  4GFQ A;  4NOI A;  4MEY A;  4XLN A;  3RZD C;  4Q4Z A;  1KH9 A;  1HI9 A;  1R9T A;  2JA8 K;  2A6H A;  1DD5 A;  2NVY A;  3S1M C;  4UOP A;  2W5X A;  1WOP A;  1INN A;  1O27 A;  1J98 A;  3E2D A;  3M8W A;  5C4J C;  2O5J A;  1IQ0 A;  4X6A K;  3GTJ C;  3PO2 C;  3DPC A;  3UNY A;  4LR2 A;  5IOT A;  2JA5 A;  3ADA C;  1ANJ A;  4CXU A;  1IS1 A;  1K83 K;  2JA6 C;  3OPF A;  4BXX K;  2IFY A;  1ED8 A;  4BBR K;  5GRR A;  5M5W K;  3NKN A;  1ZED A;  4QIW L;  3TWZ A;  3RZD K;  3MK2 A;  3L4J A;  4Q5S A;  1I6V A;  4P9S A;  5EGE A;  2E2H C;  3S1M K;  1VJE A;  4YG2 A;  5IP9 C;  2W8S A;  1I3Q A;  2A69 A;  3HKZ D;  4GTL A;  1F9N A;  3M7V A;  1YCL A;  2XCR B;  1BJT A;  1TWG A;  5C4J K;  4KN7 A;  3FHZ A;  5L0E A;  1EK8 A;  1EH1 A;  3GTJ K;  1WQH A;  3PO2 K;  2VUM A;  3T00 A;  4B56 A;  3AH5 A;  1XZP A;  4A3G C;  1EI6 A;  2YU9 C;  4GTE A;  2JA6 K;  5E68 A;  3GTO A;  1F93 A;  4LK1 A;  3IGZ B;  3RZO C;  1HJK A;  1PJ6 A;  1WCM A;  3S1R C;  3GTK C;  5IP9 K;  4LRD A;  3WAX A;  4NWJ A;  5L0K A;  1V5V A;  3CQZ C;  3MK0 A;  1O2B A;  1JQW A;  3BDF A;  3FOE A;  1WSV A;  5L0B A;  5M3M K;  1IL2 A;  3GEH A;  4A3G K;  1AJA A;  5LQQ A;  2GA3 A;  4O2D A;  2R93 A;  4UPH A;  3FKI C;  4G0V A;  3M8Y A;  3GTP C;  3BUE A;  3RZO K;  4OIP A;  1K7H A;  1YX2 A;  2WB1 L;  1E1Z P;  3GTG C;  1XXB A;  3B5Q A;  3S1R K;  3S1Q C;  3GTK K;  4MY4 A;  4OIN A;  4MHX A;  3AQO A;  3CQZ K;  4GTA A;  2PA8 D;  4J3N A;  4UOO A;  3CMR A;  2D1G A;  3AD7 C;  4GTB A;  1ELZ A;  4A93 K;  4RMF A;  3H3V L;  2IUC B;  2CFA A;  3HOW C;  3S14 C;  5M3F K;  5LRN A;  1KHK A;  4UPI A;  3ERE D;  3TTG A;  1P49 A;  3FKI K;  2ZFZ A;  5C66 A;  1WIH A;  3GTP K;  4UPK A;  4GTX A;  3DXJ A;  1N2K A;  1UV7 A;  3GTG K;  4C3J C;  3S1Q K;  4KMU A;  3QX3 A;  4GTD A;  2GSU A;  1EW8 A;  4GTW A;  4QAX A;  2PMZ D;  2NVX C;  3GTL C;  3HOU C;  1AJC A;  3N0B A;  1O25 A;  2P8T A;  3A52 A;  3EQL A;  3HOW K;  3S14 K;  4OIO A;  4MIV A;  2A6E A;  4Y7N C;  4GZY A;  4KC6 A;  2JA7 A;  1VLO A;  1ALJ A;  1DCP A;  2W5R A;  1KH5 A;  3HXA A;  2BE5 A;  2E2I C;  1KHJ A;  4A3C C;  2CW0 A;  4KB4 A;  2R92 C;  2ZUE A;  2B63 A;  1ZBS A;  3UN3 A;  2NVX K;  3BP3 A;  3GTL K;  3HOU K;  2Y3P A;  4LRC A;  5LRM A;  4C3I C;  1DCH A;  3CAG A;  4XSX A;  4A3J C;  2E2H A;  4WJ3 M;  3Q3Q A;  3OT9 A;  1ZXO A;  4G0W A;  1ALK A;  1XZP B;  4UPL A;  5D4D A;  3OEP A;  1WSR A;  5HRT A;  4Y7N K;  2PHC B;  4BY7 C;  2V6U A;  5IOQ A;  2PPB A;  4KAY A;  3TG0 A;  3WAY A;  3NUH A;  1EQR A;  4JK1 A;  1WOO A;  1F7V A;  1YNN A;  4P5A A;  2YU9 A;  2E2I K;  1Y7A A;  4KAT A;  3LAP A;  5AJ9 A;  3IPJ A;  4PAA A;  4A3C K;  1TWF C;  1ALH A;  3NKO A;  1E2S P;  4KM4 A;  2R92 K;  5IYD C;  5DLV A;  4OIR A;  3TFJ A;  1AJD A;  4CYS A;  4C3I K;  4A3J K;  1TWA C;  3M4O C;  3AD8 C;  3WOD A;  4M1X A;  1SFO A;  1WQG A;  1HDH A;  4BY7 K;  1EFW A;  2R7Z A;  3UN5 A;  1J6V A;  1TWH C;  3L4K A;  4OIQ A;  4XCH A;  4LJZ A;  1I50 C;  3UO0 A;  1X31 C;  3K7A C;  4LR9 A;  1TWF K;  4FM9 A;  4YR1 A;  5INH A;  4ILD A;  5IYD K;  3ED4 A;  3GTQ A;  2XR9 A;  2GAG C;  1IW7 A;  3N3Y A;  3GTG A;  1TWA K;  4A3I C;  3NVL A;  3M4O K;  2CFA B;  4GTZ A;  1URB A;  1ZYR A;  2W5V A;  4LLG A;  3JST A;  1L0W A;  5C3E C;  1R9T C;  1TWH K;  2NVY C;  4AYB D;  3GDZ A;  2W7V A;  1Y1W A;  1I50 K;  4A3D C;  3V4G A;  1Y1V A;  4A93 C;  3G4A A;  1ZEF A;  3K7A K;  1XXC A;  4QIW D;  5EGH A;  5L46 A;  3HOZ C;  2JA5 C;  4KN4 A;  4PAB A;  3TFH A;  1J6W A;  1O2F B;  1O26 A;  4KM8 A;  4A3K C;  1EW2 A;  3WAW A;  3S0X A;  2Y0S D;  3GTM A;  3S15 C;  4A3I K;  1JVI A;  1J6X A;  4CYR A;  4FDJ A;  4LRE A;  5C3E K;  1R9T K;  4BLA A;  1Y6V A;  4GTY A;  2QZU A;  2EBB A;  2NVY K;  5FLM C;  1I3Q C;  4A3D K;  3UN2 A;  3NKP A;  1BS2 A;  2E2J C;  2XCQ A;  3IGY B;  1XXA A;  1SHQ A;  3T01 A;  4BY1 C;  1XPP A;  5M5X K;  2VUM C;  1TWC C;  3HOZ K;  2JA5 K;  1ED9 A;  2NVT C;  2JH3 A;  4A3K K;  3GEE A;  4ZG7 A;  1IE0 A;  5FJ8 K;  3S15 K;  4BBS C;  3VA7 A;  4FDI A;  5IP7 C;  1HQM A;  3GEI A;  2W5W A;  2R92 A;  4G7H A;  1K83 A;  3GTO C;  5TMC A;  4XSZ A;  4G7Z A;  2GAH C;  4QJV A;  3HOY C;  4GT9 A;  4BKW A;  1O98 A;  4G7O A;  4A3E K;  3SZZ A;  1EQJ A;  1WCM C;  4GTF A;  5FLM K;  1WOS A;  1I3Q K;  1E33 P;  2WAQ L;  2E2J K;  1TWG K;  4ZG9 A;  4BY1 K;  1F7U A;  2VUM K;  3DYC A;  1TWC K;  1EW9 A;  1KHN A;  5GOV A;  2NVT K;  3TX0 A;  1USO A;  2ZUF A;  4LQY A;  5IJQ A;  1VH2 A;  3FOF A;  1ALI A;  3GTJ A;  4BBS K;  1BDF A;  1SMY A;  2ZKT A;  5IP7 K;  4UOR A;  4NWX A;  1E3C P;  4AH6 A;  4KM9 A;  3GTO K;  1C0A A;  2JA6 A;  3BDG A;  4G0U A;  3AD9 C;  3HOY K;  2X98 A;  2GSN A;  4LRA A;  3H3V D;  1WCM K;  3A8I A;  4KMA A;  2GSO A;  2P5M A;  3SZY A;  1XZQ A;  4A3L C;  1WQF A;  4KAR A;  1JOE A;  3H0G C;  1AJB A;  3S2H C;  2VQR A;  4C45 A;  5IYB C;  4LK0 A;  2W5S A;  3LXQ A;  4LRF A;  3MK1 A;  5IYC C;  3HKZ L;  4ZG6 A;  1O29 A;  2W5Q A;  4CXS A;  3BP8 C;  2A68 A;  4P5B A;  3S1N C;  4WJ4 A;  4KDD A;  3GTK A;  4A3L K;  3AQP A;  1ELY A;  2V6T A;  3H0G K;  3CQZ A;  3S2H K;  1RU0 A;  1I6H C;  3A8J A;  5IYB K;  5TJ3 A;  2JA7 C;  5IYC K;  4AYB L;  2D6F C;  4ZH4 A;  2O5I A;  2KWA A;  1HQA A;  1URA A;  5JFE A;  1BGW A;  4A3F C;  3FKI A;  2ANH A;  5KXA A;  1ZQ1 C;  2GLQ A;  1AB4 A;  3S1N K;  3GTP A;  3TFI A;  3M3Y C;  4LR8 A;  1VGX A;  4KB2 A;  4KJG A;  1KQ4 A;  2B63 C;  4C3H C;  5K4P A;  1N2L A;  2G9Y A;  2Y0S L;  1ZEB A;  4KAW X;  3I4N C;  1USM A;  1I6H K;  4Y52 C;  2JA7 K;  3HOX C;  2PA8 L;  4XLP A;  1TWC A;  5IOR A;  4QJV B;  3KD8 A;  4KAS A;  1B8J A;  1ELX A;  3LAJ A;  1GE9 A;  3NKM A;  2RGR A;  2NVQ C;  4A3F K;  3M3Y K;  3T02 A;  4YFN A;  2B63 K;  3GIR A;  4C3H K;  5DLT A;  3S2D C;  2XRG A;  4LR7 A;  4MEX A;  2E2H K;  3I4N K;  2RH6 A;  3I4M C;  4LRB A;  2NVX A;  3GTL A;  1KHL A;  1SFO C;  4Y52 K;  1O99 A;  3M8Z A;  1SHN A;  3WBH A;  3A8K A;  2XCO A;  1ISE A;  2R7Z C;  4WIL A;  4A3E C;  2W5T A;  1PJ7 A;  1O24 A;  3HOX K;  2FQO A;  1EJJ A;  2PMZ L;  3BDG B;  3G4C A;  1TWG C;  5IOS A;  2YU9 K;  2NVQ K;  4GTC A;  1O28 A;  3NKR A;  1YNJ A;  3ORE A;  4ZGA A;  3WAV A;  4FZB A;  4C2M C;  4KAV A;  1ANI A;  3S2D K;  2E2I A;  1XZQ B;  1KH7 A;  4YFX A;  5M5Y K;  3GTQ C;  3S16 C;  4KMH A;  1VRQ C;  3MML B;  1ZVU A;  3I4M K;  1DCO A;  1IBA A;  1SFO K;  4LOW A;  1B4B A;  2V6S A;  4TN0 A;  2R7Z K;  3HOV C;  2FQT A;  3H0G A;  4A3B C;  5JVO A;  5C44 C;  5C4X C;  5HL8 A;  1Y1W C;  1Y1V C;  4A3M C; 
#chains in the Genus database with same CATH homology
 4KMD A;  1TWF A;  4CXK A;  5CHP A;  1B4A A;  4BLB A;  1TWA A;  4N7T A;  2W8D A;  3NKQ A;  5DLW A;  5LIA A;  1TWH A;  5CJ9 A;  3LPX A;  1O2A A;  3IDD A;  1I50 A;  3N0C A;  3BDH A;  5IJS A;  4KJD A;  4DDQ A;  1KH4 A;  2IUC A;  1FSU A;  1AUK A;  4GFQ A;  1KH9 A;  1R9T A;  1DD5 A;  2NVY A;  4UOP A;  2W5X A;  1O27 A;  3E2D A;  3M8W A;  3DPC A;  3UNY A;  4LR2 A;  5IOT A;  2JA5 A;  1ANJ A;  4CXU A;  1IS1 A;  3OPF A;  2IFY A;  1ED8 A;  5GRR A;  3NKN A;  1ZED A;  3TWZ A;  3MK2 A;  3L4J A;  5EGE A;  2W8S A;  1I3Q A;  4GTL A;  1F9N A;  3M7V A;  2XCR B;  1BJT A;  1TWG A;  3FHZ A;  5L0E A;  1EK8 A;  1EH1 A;  2VUM A;  1WQH A;  3T00 A;  4B56 A;  3AH5 A;  1EI6 A;  4GTE A;  3GTO A;  3IGZ B;  1HJK A;  1WCM A;  4LRD A;  3WAX A;  4NWJ A;  5L0K A;  3MK0 A;  1O2B A;  3BDF A;  3FOE A;  5L0B A;  1AJA A;  5LQQ A;  2GA3 A;  2R93 A;  4UPH A;  4G0V A;  3M8Y A;  3BUE A;  1K7H A;  1E1Z P;  3B5Q A;  1XXB A;  4MY4 A;  4MHX A;  3AQO A;  4GTA A;  4J3N A;  4UOO A;  3CMR A;  2D1G A;  4GTB A;  1ELZ A;  2IUC B;  2CFA A;  5LRN A;  1KHK A;  4UPI A;  3ERE D;  1P49 A;  2ZFZ A;  5C66 A;  4UPK A;  1WIH A;  4GTX A;  1N2K A;  4C3J C;  3QX3 A;  4GTD A;  2GSU A;  1EW8 A;  4GTW A;  4QAX A;  1AJC A;  3N0B A;  1O25 A;  3A52 A;  4MIV A;  4KC6 A;  2JA7 A;  1ALJ A;  2W5R A;  1KH5 A;  1KHJ A;  4KB4 A;  2B63 A;  1ZBS A;  3UN3 A;  4LRC A;  2Y3P A;  5LRM A;  4C3I C;  3CAG A;  2E2H A;  3Q3Q A;  3OT9 A;  1ZXO A;  4G0W A;  1ALK A;  4UPL A;  3OEP A;  5HRT A;  2PHC B;  5IOQ A;  4KAY A;  3TG0 A;  3WAY A;  3NUH A;  5AJ9 A;  2YU9 A;  4P5A A;  1Y7A A;  4KAT A;  3LAP A;  1ALH A;  3NKO A;  1E2S P;  4KM4 A;  5DLV A;  1AJD A;  4CYS A;  1SFO A;  4M1X A;  1WQG A;  1HDH A;  2R7Z A;  3UN5 A;  3L4K A;  3UO0 A;  4LR9 A;  4FM9 A;  4YR1 A;  5INH A;  4ILD A;  3ED4 A;  3GTQ A;  2XR9 A;  3N3Y A;  3GTG A;  3NVL A;  2CFA B;  4GTZ A;  1URB A;  2W5V A;  1Y1W A;  3V4G A;  1Y1V A;  1ZEF A;  3G4A A;  1XXC A;  5EGH A;  1O26 A;  4KM8 A;  1EW2 A;  3WAW A;  3S0X A;  3GTM A;  4CYR A;  4FDJ A;  4LRE A;  4BLA A;  1Y6V A;  4GTY A;  2QZU A;  3UN2 A;  3NKP A;  2XCQ A;  3IGY B;  1XXA A;  1SHQ A;  3T01 A;  1ED9 A;  2JH3 A;  4ZG7 A;  3VA7 A;  4FDI A;  2W5W A;  2R92 A;  1K83 A;  4GT9 A;  4BKW A;  1O98 A;  1EQJ A;  3SZZ A;  4GTF A;  1E33 P;  4ZG9 A;  3DYC A;  1EW9 A;  1KHN A;  5GOV A;  3TX0 A;  5IJQ A;  4LQY A;  3FOF A;  1ALI A;  3GTJ A;  2ZKT A;  4UOR A;  4NWX A;  1E3C P;  4KM9 A;  2JA6 A;  3BDG A;  4G0U A;  2X98 A;  4LRA A;  2GSN A;  4KMA A;  2GSO A;  2P5M A;  3SZY A;  1WQF A;  4KAR A;  1AJB A;  2VQR A;  2W5S A;  3LXQ A;  4LRF A;  3MK1 A;  4ZG6 A;  1O29 A;  2W5Q A;  4CXS A;  4P5B A;  4KDD A;  3GTK A;  3AQP A;  1ELY A;  3CQZ A;  5TJ3 A;  2KWA A;  1HQA A;  1URA A;  5JFE A;  1BGW A;  3FKI A;  2ANH A;  5KXA A;  2GLQ A;  1AB4 A;  3GTP A;  4LR8 A;  4KB2 A;  4KJG A;  1KQ4 A;  4C3H C;  5K4P A;  1N2L A;  2G9Y A;  1ZEB A;  4KAW X;  1TWC A;  5IOR A;  3KD8 A;  4KAS A;  1B8J A;  1ELX A;  3LAJ A;  1GE9 A;  3NKM A;  2RGR A;  3T02 A;  5DLT A;  2XRG A;  4LR7 A;  2RH6 A;  4LRB A;  2NVX A;  3GTL A;  1KHL A;  1O99 A;  3M8Z A;  1SHN A;  3WBH A;  2XCO A;  1ISE A;  2W5T A;  1O24 A;  1EJJ A;  3BDG B;  3G4C A;  5IOS A;  4GTC A;  1O28 A;  3NKR A;  3ORE A;  4ZGA A;  3WAV A;  4FZB A;  4C2M C;  4KAV A;  1ANI A;  2E2I A;  1KH7 A;  4KMH A;  3MML B;  1ZVU A;  1B4B A;  4TN0 A;  3H0G A;  5JVO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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