4LR2A

Crystal structure of human enpp4 (apo)
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
Knots found
sequence length
379
structure length
379
Chain Sequence
LPPKLLLVSFDGFRADYLKNYEFPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDAVTKKHFSDSNDKDPFWWNEAVPIWVTNQLQENRSSAAAMWPGTDVPIHDTISSYFMNYNSSVSFEERLNNITMWLNNSNPPVTFATLYWEEPDASGHKYGPEDKENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSYYTLIDLSPVAAILPKINRTEVYNKLKNCSPHMNVYLKEDIPNRFYYQHNDRIQPIILVADEGWTIVLNESSQKLGDHGYDNSLPSMHPFLAAHGPAFHKGYKHSTINIVDIYPMMCHILGLKPHPNNGTFGHTKCLLVDQWCI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Molecular basis of purinergic signal metabolism by ectonucleotide pyrophosphatase/phosphodiesterases 4 and 1 and implications in stroke.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Bis(5'-adenosyl)-triphosphatase ENPP4
total genus 128
structure length 379
sequence length 379
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.6.1.29: Bis(5'-adenosyl)-triphosphatase.
pdb deposition date 2013-07-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.180 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Gyrase A; domain 2 4lr2A02
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4lr2A01
3DPCA 1EQJA 4LR9A 2W5WA 3ED4A 4LRCA 2IUCB 1ZEFA 3E2DA 3SZZA 1ZEBA 1E33P 2RH6A 3T01A 3NKRA 1EW9A 2W5RA 1AJDA 5LRNA 3CMRA 1E3CP 4MHXA 5L0EA 1EI6A 2W5SA 5HRTA 1P49A 1HDHA 1FSUA 1SHQA 2ANHA 1HQAA 1AJCA 4KAYA 1EJJA 4LRDA 4FDJA 3WAWA 3Q3QA 5GRRA 1ZEDA 3BDGB 3TWZA 1N2KA 5DLTA 3SZYA 4LR8A 4NWXA 4UPIA 1URBA 4CYRA 3IGZB 2GSOA 3M7VA 1KHKA 1ED8A 1AJBA 3IDDA 1ALIA 3WBHA 2W5QA 5LQQA 4CYSA 1E1ZP 3M8ZA 3IGYB 3NKPA 1AJAA 3NKMA 4UPLA 2VQRA 5L0BA 3NKNA 1EW8A 4LRAA 5C66A 1URAA 5INHA 4KJGA 1AUKA 3UN2A 5IJQA 5IJSA 4LRBA 2ZKTA 1ALHA 1Y6VA 3OT9A 1ALKA 5KXAA 1ANJA 2W5VA 4CXSA 1KH7A 4ZG6A 5LRMA 5LIAA 3UN5A 2X98A 1KH9A 3LXQA 2GSNA 4N7TA 3WAXA 5TJ3A 4YR1A 1K7HA 4LR2A 1KHJA 1EW2A 2W5XA 1KH5A 4GTYA 1HJKA 2W5TA 2XRGA 1N2LA 2W8DA 3DYCA 1ANIA 3WAYA 4UPHA 1ELYA 4LQYA 4UPKA 3MK2A 4LR7A 1ED9A 3A52A 4GTXA 3T00A 3TX0A 4MIVA 3MK1A 3UNYA 1KHNA 4UOPA 2W8SA 5EGEA 1KHLA 3MK0A 4GTWA 4GTZA 4ZGAA 3NKOA 1E2SP 1O99A 2IUCA 4B56A 1B8JA 2QZUA 3TG0A 5DLVA 5AJ9A 1ELXA 4ZG9A 4CXKA 4CXUA 2GSUA 5DLWA 2IFYA 3WAVA 3UN3A 1KH4A 5GOVA 3BDHA 4TN0A 2GLQA 2GA3A 4LRFA 4LREA 5K4PA 1ELZA 4KAVA 2XR9A 1Y7AA 1ALJA 4FDIA 3BDGA 3T02A 4QAXA 1O98A 3M8WA 2G9YA 1SHNA 3NVLA 4UORA 4KM4A 2D1GA 4MY4A 4NWJA 3KD8A 4ZG7A 4KJDA 5L0KA 3B5QA 3M8YA 5EGHA 3NKQA 3BDFA 3UO0A 4UOOA
chains in the Genus database with same CATH superfamily
1K83C 1WCMK 2E2JK 2E2IK 1EQJA 3SZZA 4LRCA 3E2DA 5E68A 4GTAA 3GTJK 4WILA 3ERED 1TWCA 5M3MK 4RMFA 3GTOC 3HOZK 4Y52K 1I3QA 2B63K 2A69A 4YFNA 3GTGC 2JA7K 1O2BA 1BGWA 2PA8D 3WAWA 3JSTA 3MMLB 2FQTA 3SZYA 4CYRA 3RZDC 1JOEA 2NVYC 5FJ8K 2JA6A 4A3KC 4BBRC 1ED8A 1AJBA 3GEIA 5IP9K 4BY7C 3S15C 4GTCA 3PO2K 3S0XA 3IGYB 4A3JK 1AJAA 1EH1A 3TTGA 5C44C 4BY1C 2PMZL 4AH6A 2R93A 3NKNA 1XZQB 4LOWA 1AB4A 2ZKTA 2CFAB 1ALHA 1ALKA 5HL8A 1O25A 3GEHA 5IOQA 4G0WA 1BS2A 3CQZC 4CXSA 1ZQ1C 1KH7A 4ZG6A 4BXXK 3LPXA 1VRQC 5C4JK 2R7ZA 1IW7A 3S1QC 3GTMA 4MEXA 1K7HA 1YX2A 1KH5A 4A3BC 2W5TA 3H3VL 2PPBA 3S17K 5IYDC 3HOWC 1ISEA 4UPHA 3HOYC 3M3YK 4Y7NK 2YU9K 1PJ6A 1ED9A 4GTXA 1DCPA 2WAQL 4MIVA 1INNA 3MK1A 2CW0A 3L4JA 4UOPA 3TFHA 3GSIA 1KHLA 4ZGAA 4A93C 3V4GA 1B8JA 3HOXK 1VGXA 1EQRA 4KASA 4A3KK 5DLVA 5AJ9A 3GTLK 2E2IC 1WCMC 2GSUA 5C3EK 2E2JC 1IL2A 3GTQK 2VUMA 4CXUA 4TN0A 4KMDA 4LRFA 4LREA 5C44K 5K4PA 3GTJC 2Y0SL 2E2HA 2RGRA 4OINA 4FDIA 3HOZC 4Y52C 3N3YA 3TFIA 2GAGC 2A68A 4A3IK 2B63C 1V5VA 3I4NK 2JA7C 3NVLA 2KWAA 4A3LC 1O2AA 4MY4A 4NWJA 1O24A 1IBAA 3B5QA 2WAQD 4KAWX 5EGHA 3BDFA 4UOOA 1USOA 1WIHA 4G0UA 4LR9A 5IP9C 1XZQA 4KDDA 3PO2C 3GTKK 3HOVC 2NVXA 4LJZA 4A3JC 4BLAA 3NKRA 1EW9A 4PAAA 4BKWA 3BP3A 1YCLA 5L0EA 1EI6A 4PABA 2W5SA 5HRTA 1P49A 1FSUA 3L4KA 1SFOA 1K83A 3AH5A 4GTEA 1WSRA 4FDJA 1I50A 5GRRA 2Y0SD 3TWZA 3OPFA 5DLTA 4BXXC 4QIWD 5C4JC 1L0WA 3S1MK 2GSOA 3GTPK 3GTOA 1KHKA 3WBHA 2D6FC 3GTGA 1E1ZP 1O29A 3K7AK 1WOPA 1TWGK 3NKPA 4UPLA 4J3NA 4AYBD 3S17C 1WORA 1XXBA 1WQGA 2JA5K 4LRAA 5INHA 5C66A 1TWFA 4P5BA 2NVYA 3M3YC 4BBSK 5IJSA 1XPPA 4GTFA 4Y7NC 2YU9C 1F7VA 5JFEA 4OIQA 1G51A 4C3JK 4OIOA 2W5VA 3AD8C 4A3CK 3AQOA 4MQ9A 4A3LK 5LRMA 4P9SA 2JA8K 2R92A 2X98A 2GSNA 4N7TA 3HOXC 4G7ZA 1J6WA 4MEYA 3GTLC 4WJ3M 1R9TK 3H0GK 5C3EC 1J6XA 3GTQC 4GTYA 3HOVK 3CQZA 3DYCA 1ZXOA 3WAYA 3N0CA 4KC6A 4A3MK 1KQ4A 1PJ7A 4UPKA 3MK2A 2VUMK 4LR7A 3RZOK 4A3IC 3NUHA 1KHNA 3I4NC 3N0BA 1EK8A 1TWAA 5FLMK 1O99A 2XCQA 5IOTA 1HI9A 3LAJA 1X31C 4ZG9A 3S1RC 4KARA 5DLWA 2NVTK 3WAVA 5GOVA 3GTKC 1Y1WA 4KB4A 4XSXA 1Y1VA 1WQFA 1ZBSA 2ZUFA 4A3GK 4KMUA 4QAXA 4YFXA 1O98A 4KM8A 2E2IA 1WCMA 3AD7C 1O28A 5IORA 3WODA 1I6VA 3BP8C 2P8TA 4KM4A 2PMZD 4LK1A 3GTJA 5L0KA 3FKIK 4KJDA 3CAGA 1XXCA 3G4AA 2A6EA 3NKQA 3S1MC 4A3FK 1DD5A 3DPCA 3GTPC 1I50K 1B4AA 2B63A 2W5WA 3ED4A 3S16K 1ZEFA 1ZEBA 1E33P 3K7AC 2JA7A 5IYBC 1TWGC 2RH6A 2V6SA 1TWHK 3T01A 2A6HA 4C3HK 2JA5C 3CMRA 1E3CP 4MHXA 3A8IA 4BBSC 1HDHA 1O27A 2JH3A 2ANHA 4KAYA 4LRDA 4GTBA 2WB1L 3H3VD 3EQLA 3S1NK 4OIPA 4C3JC 1JQWA 1TWFK 4ILDA 3BDGB 1TWCK 4KMAA 4XLNA 4A3CC 4LR8A 3GIRA 4UPIA 2JA8C 4C45A 1I3QK 3IGZB 1F9NA 4X6AK 3S1RK 3IDDA 1ALIA 2P5MA 2W5QA 5LQQA 4CYSA 1R9TC 3H0GC 2R92K 5CHPA 5L0BA 1EW8A 1URAA 2JA6K 1AUKA 2FQOA 5IJQA 1YNNA 4A3MC 1RU0A 3UN2A 4BLBA 2VUMC 4GTLA 3A8KA 4LK0A 3RZOC 2ZFZA 4GZYA 2R93K 3G4CA 5LIAA 4FM9A 3UN5A 5FLMC 4FZBA 3LXQA 3WAXA 1DCHA 4KMHA 2YU9A 4LR2A 4P5AA 4KATA 1HJKA 5TMCA 1TWAK 2NVTC 2W8DA 1WSVA 2R7ZK 5IYBK 1ANIA 5IYCK 5M5WK 3GTMK 4LQYA 3AQPA 1XXAA 4A3GC 3TX0A 3FOEA 4O2DA 1UV7A 4C2MK 1Y1WK 3GTLA 3M4OK 2W8SA 2GAHC 3GDZA 4A3EK 1O26A 4GTWA 4B56A 1ZVUA 3FKIC 1IS1A 2QZUA 1J98A 1O2FB 4A3FC 3HOUK 4CXKA 4Q4ZA 4YFKA 1I50C 3FHZA 3OEPA 3PO3K 3UN3A 1KH4A 3S16C 3S2DK 1IE0A 3BDHA 1PJ5A 1GE9A 5TMFA 3I4MK 1TWHC 4C3HC 4WJ4A 4DDQA 4C3IK 4OIRA 1VLOA 3IPJA 3BDGA 2NVQC 5C4XK 5M3FK 1JVIA 5CJ9A 2G9YA 3M8WA 4ZH4A 1SHNA 4UORA 3S1NC 2D1GA 3GTKA 5M5XK 4QJVB 1TWFC 2E2HK 1BJTA 1TWCC 3DXJA 4ZG7A 3A8JA 3M8YA 3HKZL 1I3QC 4KN4A 3UO0A 4X6AC 5IP7K 1B4BA 1I6HK 3QX3A 2IUCB 5JVOA 2W7VA 1SMYA 2R92C 3FOFA 2W5RA 2BE5A 5L46A 1AJDA 5LRNA 2JA6C 1J6VA 1SHQA 3GTPA 4A3DK 1AJCA 1WQHA 1EJJA 1HQAA 2NVXK 4G7OA 3S2HK 2V6TA 3Q3QA 1ZEDA 3S14K 2V6UA 1TWGA 1N2KA 3AD9C 3HXAA 2R93C 4GTDA 3TFJA 4NWXA 1URBA 4NOIA 2JA5A 1SFOK 1K83K 3M7VA 1DCOA 1HQMA 4G7HA 2ZUEA 3M8ZA 1TWAC 3NKMA 1F93A 1XZPB 2R7ZC 2VQRA 4KB2A 1WOOA 5IYCC 2XCOA 3HKZD 4KJGA 3GTMC 3GTOK 4LLGA 4LRBA 1F7UA 1Y6VA 3OT9A 2NVQK 3GTGK 4JK1A 1BDFA 1Y1WC 4C2MC 1ANJA 1R9TA 3H0GA 5KXAA 3M4OC 4GFQA 3BUEA 4A3EC 1Y1VC 3RZDK 4Q5SA 2NVYK 1KH9A 5D4DA 5TJ3A 4BBRK 4YR1A 4BY7K 3S15K 1EW2A 1KHJA 4XLPA 2W5XA 3HOUC 3PO3C 2XRGA 1N2LA 3S2DC 4BY1K 4XCHA 1VJEA 3I4MC 2XCRB 1USMA 4QIWL 1ELYA 2O5IA 2EBBA 4GT9A 4C3IC 3A52A 4QJVA 3T00A 1C0AA 5C4XC 3UNYA 3GEEA 3CQZK 5EGEA 2PHCB 3MK0A 1WOSA 3OREA 4GTZA 4AYBL 2E2HC 3NKOA 1E2SP 2IUCA 3S1QK 5M5YK 4M1XA 3TG0A 1ELXA 2WB1D 5IP7C 4A3BK 2IFYA 4KN7A 1I6HC 2CFAA 3LAPA 4G0VA 5IYDK 3HOWK 2GLQA 2GA3A 2PA8L 4YG2A 1ELZA 3HOYK 4KAVA 2XR9A 1VH2A 1Y7AA 4XSZA 3FKIA 2O5JA 2Y3PA 1ALJA 3T02A 1YNJA 1EFWA 4A3DC 1ZYRA 2NVXC 3ADAC 3VA7A 3GTQA 3S2HC 4KM9A 1IQ0A 3S14C 1Y1VK 4A93K 1TWHA 3KD8A 5IOSA 1XZPA 1SFOC
chains in the Genus database with same CATH topology
1EQJA 4LRCA 3SZZA 3E2DA 4GTAA 3ERED 1TWCA 1I3QA 1O2BA 1BGWA 3WAWA 3MMLB 3SZYA 4CYRA 2JA6A 1ED8A 1AJBA 4GTCA 3S0XA 3IGYB 1AJAA 1EH1A 2R93A 3NKNA 1AB4A 2ZKTA 2CFAB 1ALHA 1ALKA 1O25A 5IOQA 4G0WA 4CXSA 1KH7A 4ZG6A 3LPXA 2R7ZA 3GTMA 1K7HA 1KH5A 2W5TA 1ISEA 4UPHA 1ED9A 4GTXA 4MIVA 3MK1A 3L4JA 4UOPA 1KHLA 4ZGAA 3V4GA 1B8JA 4KASA 5DLVA 5AJ9A 4CXUA 2GSUA 2VUMA 4TN0A 4KMDA 4LRFA 4LREA 5K4PA 2E2HA 2RGRA 4FDIA 3N3YA 3NVLA 2KWAA 1O2AA 4MY4A 4NWJA 1O24A 3B5QA 4KAWX 5EGHA 3BDFA 4UOOA 1WIHA 4G0UA 4LR9A 4KDDA 2NVXA 4BLAA 3NKRA 1EW9A 4BKWA 5L0EA 1EI6A 2W5SA 5HRTA 1P49A 1FSUA 3L4KA 1SFOA 1K83A 3AH5A 4GTEA 4FDJA 1I50A 5GRRA 3TWZA 3OPFA 5DLTA 2GSOA 3GTOA 1KHKA 3WBHA 3GTGA 1E1ZP 1O29A 3NKPA 4UPLA 4J3NA 1XXBA 1WQGA 4LRAA 5C66A 5INHA 1TWFA 4P5BA 2NVYA 5IJSA 4GTFA 5JFEA 2W5VA 5LRMA 3AQOA 2R92A 2X98A 2GSNA 4N7TA 4GTYA 3CQZA 3DYCA 1ZXOA 3WAYA 3N0CA 4KC6A 1KQ4A 4UPKA 3MK2A 4LR7A 3NUHA 1KHNA 3N0BA 1EK8A 1TWAA 1O99A 2XCQA 5IOTA 3LAJA 4ZG9A 4KARA 5DLWA 3WAVA 5GOVA 1Y1WA 4KB4A 1Y1VA 1WQFA 1ZBSA 4QAXA 1O98A 4KM8A 2E2IA 1WCMA 1O28A 5IORA 4KM4A 3GTJA 5L0KA 4KJDA 3CAGA 1XXCA 3G4AA 3NKQA 3DPCA 1DD5A 1B4AA 2B63A 2W5WA 3ED4A 1ZEFA 1ZEBA 1E33P 2JA7A 2RH6A 3T01A 3CMRA 1E3CP 4MHXA 1HDHA 1O27A 2JH3A 2ANHA 4KAYA 4LRDA 4GTBA 4C3JC 4ILDA 3BDGB 4KMAA 4LR8A 4UPIA 3IGZB 1F9NA 3IDDA 1ALIA 2P5MA 2W5QA 5LQQA 4CYSA 5CHPA 5L0BA 1EW8A 1URAA 1AUKA 3UN2A 5IJQA 4BLBA 4GTLA 2ZFZA 3G4CA 5LIAA 4FM9A 3UN5A 4FZBA 3LXQA 3WAXA 4KMHA 2YU9A 4LR2A 4P5AA 4KATA 1HJKA 2W8DA 1ANIA 4LQYA 3AQPA 1XXAA 3TX0A 3FOEA 3GTLA 2W8SA 1O26A 4GTWA 4B56A 1ZVUA 1IS1A 2QZUA 4CXKA 3FHZA 3OEPA 3UN3A 1KH4A 3BDHA 1GE9A 4C3HC 4DDQA 3BDGA 5CJ9A 3M8WA 2G9YA 1SHNA 4UORA 2D1GA 3GTKA 1BJTA 4ZG7A 3M8YA 3UO0A 1B4BA 3QX3A 2IUCB 5JVOA 3FOFA 2W5RA 1AJDA 5LRNA 1SHQA 3GTPA 1HQAA 1AJCA 1WQHA 1EJJA 3Q3QA 1ZEDA 1TWGA 1N2KA 4GTDA 4NWXA 1URBA 2JA5A 3M7VA 3M8ZA 3NKMA 2VQRA 4KB2A 2XCOA 4KJGA 4LRBA 1Y6VA 3OT9A 5KXAA 1ANJA 4C2MC 1R9TA 3H0GA 4GFQA 3BUEA 1KH9A 5TJ3A 4YR1A 1KHJA 1EW2A 2W5XA 2XRGA 1N2LA 2XCRB 1ELYA 4GT9A 4C3IC 3A52A 3T00A 3UNYA 5EGEA 2PHCB 3MK0A 3OREA 4GTZA 3NKOA 1E2SP 2IUCA 4M1XA 3TG0A 1ELXA 2IFYA 2CFAA 3LAPA 4G0VA 2GLQA 2GA3A 1ELZA 4KAVA 2XR9A 1Y7AA 3FKIA 1ALJA 2Y3PA 3T02A 3VA7A 3GTQA 4KM9A 1TWHA 3KD8A 5IOSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DPC A;  1EQJ A;  4LR9 A;  2W5W A;  3ED4 A;  4LRC A;  2IUC B;  1ZEF A;  3E2D A;  3SZZ A;  1ZEB A;  1E33 P;  2RH6 A;  3T01 A;  3NKR A;  1EW9 A;  2W5R A;  1AJD A;  5LRN A;  3CMR A;  1E3C P;  4MHX A;  5L0E A;  1EI6 A;  2W5S A;  5HRT A;  1P49 A;  1HDH A;  1FSU A;  1SHQ A;  2ANH A;  1HQA A;  1AJC A;  4KAY A;  1EJJ A;  4LRD A;  4FDJ A;  3WAW A;  3Q3Q A;  5GRR A;  1ZED A;  3BDG B;  3TWZ A;  1N2K A;  5DLT A;  3SZY A;  4LR8 A;  4NWX A;  4UPI A;  1URB A;  4CYR A;  3IGZ B;  2GSO A;  3M7V A;  1KHK A;  1ED8 A;  1AJB A;  3IDD A;  1ALI A;  3WBH A;  2W5Q A;  5LQQ A;  4CYS A;  1E1Z P;  3M8Z A;  3IGY B;  3NKP A;  1AJA A;  3NKM A;  4UPL A;  2VQR A;  5L0B A;  3NKN A;  1EW8 A;  4LRA A;  5C66 A;  1URA A;  5INH A;  4KJG A;  1AUK A;  3UN2 A;  5IJQ A;  5IJS A;  4LRB A;  2ZKT A;  1ALH A;  1Y6V A;  3OT9 A;  1ALK A;  5KXA A;  1ANJ A;  2W5V A;  4CXS A;  1KH7 A;  4ZG6 A;  5LRM A;  5LIA A;  3UN5 A;  2X98 A;  1KH9 A;  3LXQ A;  2GSN A;  4N7T A;  3WAX A;  5TJ3 A;  4YR1 A;  1K7H A;  4LR2 A;  1KHJ A;  1EW2 A;  2W5X A;  1KH5 A;  4GTY A;  1HJK A;  2W5T A;  2XRG A;  1N2L A;  2W8D A;  3DYC A;  1ANI A;  3WAY A;  4UPH A;  1ELY A;  4LQY A;  4UPK A;  3MK2 A;  4LR7 A;  1ED9 A;  3A52 A;  4GTX A;  3T00 A;  3TX0 A;  4MIV A;  3MK1 A;  3UNY A;  1KHN A;  4UOP A;  2W8S A;  5EGE A;  1KHL A;  3MK0 A;  4GTW A;  4GTZ A;  4ZGA A;  3NKO A;  1E2S P;  1O99 A;  2IUC A;  4B56 A;  1B8J A;  2QZU A;  3TG0 A;  5DLV A;  5AJ9 A;  1ELX A;  4ZG9 A;  4CXK A;  4CXU A;  2GSU A;  5DLW A;  2IFY A;  3WAV A;  3UN3 A;  1KH4 A;  5GOV A;  3BDH A;  4TN0 A;  2GLQ A;  2GA3 A;  4LRF A;  4LRE A;  5K4P A;  1ELZ A;  4KAV A;  2XR9 A;  1Y7A A;  1ALJ A;  4FDI A;  3BDG A;  3T02 A;  4QAX A;  1O98 A;  3M8W A;  2G9Y A;  1SHN A;  3NVL A;  4UOR A;  4KM4 A;  2D1G A;  4MY4 A;  4NWJ A;  3KD8 A;  4ZG7 A;  4KJD A;  5L0K A;  3B5Q A;  3M8Y A;  5EGH A;  3NKQ A;  3BDF A;  3UO0 A;  4UOO A; 
#chains in the Genus database with same CATH topology
 1K83 C;  1WCM K;  2E2J K;  2E2I K;  1EQJ A;  3SZZ A;  4LRC A;  3E2D A;  5E68 A;  4GTA A;  3GTJ K;  4WIL A;  3ERE D;  1TWC A;  5M3M K;  4RMF A;  3GTO C;  3HOZ K;  4Y52 K;  1I3Q A;  2B63 K;  2A69 A;  4YFN A;  3GTG C;  2JA7 K;  1O2B A;  1BGW A;  2PA8 D;  3WAW A;  3JST A;  3MML B;  2FQT A;  3SZY A;  4CYR A;  3RZD C;  1JOE A;  2NVY C;  5FJ8 K;  2JA6 A;  4A3K C;  4BBR C;  1ED8 A;  1AJB A;  3GEI A;  5IP9 K;  4BY7 C;  3S15 C;  4GTC A;  3PO2 K;  3S0X A;  3IGY B;  4A3J K;  1AJA A;  1EH1 A;  3TTG A;  5C44 C;  4BY1 C;  2PMZ L;  4AH6 A;  2R93 A;  3NKN A;  1XZQ B;  4LOW A;  1AB4 A;  2ZKT A;  2CFA B;  1ALH A;  1ALK A;  5HL8 A;  1O25 A;  3GEH A;  5IOQ A;  4G0W A;  1BS2 A;  3CQZ C;  4CXS A;  1ZQ1 C;  1KH7 A;  4ZG6 A;  4BXX K;  3LPX A;  1VRQ C;  5C4J K;  2R7Z A;  1IW7 A;  3S1Q C;  3GTM A;  4MEX A;  1K7H A;  1YX2 A;  1KH5 A;  4A3B C;  2W5T A;  3H3V L;  2PPB A;  3S17 K;  5IYD C;  3HOW C;  1ISE A;  4UPH A;  3HOY C;  3M3Y K;  4Y7N K;  2YU9 K;  1PJ6 A;  1ED9 A;  4GTX A;  1DCP A;  2WAQ L;  4MIV A;  1INN A;  3MK1 A;  2CW0 A;  3L4J A;  4UOP A;  3TFH A;  3GSI A;  1KHL A;  4ZGA A;  4A93 C;  3V4G A;  1B8J A;  3HOX K;  1VGX A;  1EQR A;  4KAS A;  4A3K K;  5DLV A;  5AJ9 A;  3GTL K;  2E2I C;  1WCM C;  2GSU A;  5C3E K;  2E2J C;  1IL2 A;  3GTQ K;  2VUM A;  4CXU A;  4TN0 A;  4KMD A;  4LRF A;  4LRE A;  5C44 K;  5K4P A;  3GTJ C;  2Y0S L;  2E2H A;  2RGR A;  4OIN A;  4FDI A;  3HOZ C;  4Y52 C;  3N3Y A;  3TFI A;  2GAG C;  2A68 A;  4A3I K;  2B63 C;  1V5V A;  3I4N K;  2JA7 C;  3NVL A;  2KWA A;  4A3L C;  1O2A A;  4MY4 A;  4NWJ A;  1O24 A;  1IBA A;  3B5Q A;  2WAQ D;  4KAW X;  5EGH A;  3BDF A;  4UOO A;  1USO A;  1WIH A;  4G0U A;  4LR9 A;  5IP9 C;  1XZQ A;  4KDD A;  3PO2 C;  3GTK K;  3HOV C;  2NVX A;  4LJZ A;  4A3J C;  4BLA A;  3NKR A;  1EW9 A;  4PAA A;  4BKW A;  3BP3 A;  1YCL A;  5L0E A;  1EI6 A;  4PAB A;  2W5S A;  5HRT A;  1P49 A;  1FSU A;  3L4K A;  1SFO A;  1K83 A;  3AH5 A;  4GTE A;  1WSR A;  4FDJ A;  1I50 A;  5GRR A;  2Y0S D;  3TWZ A;  3OPF A;  5DLT A;  4BXX C;  4QIW D;  5C4J C;  1L0W A;  3S1M K;  2GSO A;  3GTP K;  3GTO A;  1KHK A;  3WBH A;  2D6F C;  3GTG A;  1E1Z P;  1O29 A;  3K7A K;  1WOP A;  1TWG K;  3NKP A;  4UPL A;  4J3N A;  4AYB D;  3S17 C;  1WOR A;  1XXB A;  1WQG A;  2JA5 K;  4LRA A;  5INH A;  5C66 A;  1TWF A;  4P5B A;  2NVY A;  3M3Y C;  4BBS K;  5IJS A;  1XPP A;  4GTF A;  4Y7N C;  2YU9 C;  1F7V A;  5JFE A;  4OIQ A;  1G51 A;  4C3J K;  4OIO A;  2W5V A;  3AD8 C;  4A3C K;  3AQO A;  4MQ9 A;  4A3L K;  5LRM A;  4P9S A;  2JA8 K;  2R92 A;  2X98 A;  2GSN A;  4N7T A;  3HOX C;  4G7Z A;  1J6W A;  4MEY A;  3GTL C;  4WJ3 M;  1R9T K;  3H0G K;  5C3E C;  1J6X A;  3GTQ C;  4GTY A;  3HOV K;  3CQZ A;  3DYC A;  1ZXO A;  3WAY A;  3N0C A;  4KC6 A;  4A3M K;  1KQ4 A;  1PJ7 A;  4UPK A;  3MK2 A;  2VUM K;  4LR7 A;  3RZO K;  4A3I C;  3NUH A;  1KHN A;  3I4N C;  3N0B A;  1EK8 A;  1TWA A;  5FLM K;  1O99 A;  2XCQ A;  5IOT A;  1HI9 A;  3LAJ A;  1X31 C;  4ZG9 A;  3S1R C;  4KAR A;  5DLW A;  2NVT K;  3WAV A;  5GOV A;  3GTK C;  1Y1W A;  4KB4 A;  4XSX A;  1Y1V A;  1WQF A;  1ZBS A;  2ZUF A;  4A3G K;  4KMU A;  4QAX A;  4YFX A;  1O98 A;  4KM8 A;  2E2I A;  1WCM A;  3AD7 C;  1O28 A;  5IOR A;  3WOD A;  1I6V A;  3BP8 C;  2P8T A;  4KM4 A;  2PMZ D;  4LK1 A;  3GTJ A;  5L0K A;  3FKI K;  4KJD A;  3CAG A;  1XXC A;  3G4A A;  2A6E A;  3NKQ A;  3S1M C;  4A3F K;  1DD5 A;  3DPC A;  3GTP C;  1I50 K;  1B4A A;  2B63 A;  2W5W A;  3ED4 A;  3S16 K;  1ZEF A;  1ZEB A;  1E33 P;  3K7A C;  2JA7 A;  5IYB C;  1TWG C;  2RH6 A;  2V6S A;  1TWH K;  3T01 A;  2A6H A;  4C3H K;  2JA5 C;  3CMR A;  1E3C P;  4MHX A;  3A8I A;  4BBS C;  1HDH A;  1O27 A;  2JH3 A;  2ANH A;  4KAY A;  4LRD A;  4GTB A;  2WB1 L;  3H3V D;  3EQL A;  3S1N K;  4OIP A;  4C3J C;  1JQW A;  1TWF K;  4ILD A;  3BDG B;  1TWC K;  4KMA A;  4XLN A;  4A3C C;  4LR8 A;  3GIR A;  4UPI A;  2JA8 C;  4C45 A;  1I3Q K;  3IGZ B;  1F9N A;  4X6A K;  3S1R K;  3IDD A;  1ALI A;  2P5M A;  2W5Q A;  5LQQ A;  4CYS A;  1R9T C;  3H0G C;  2R92 K;  5CHP A;  5L0B A;  1EW8 A;  1URA A;  2JA6 K;  1AUK A;  2FQO A;  5IJQ A;  1YNN A;  4A3M C;  1RU0 A;  3UN2 A;  4BLB A;  2VUM C;  4GTL A;  3A8K A;  4LK0 A;  3RZO C;  2ZFZ A;  4GZY A;  2R93 K;  3G4C A;  5LIA A;  4FM9 A;  3UN5 A;  5FLM C;  4FZB A;  3LXQ A;  3WAX A;  1DCH A;  4KMH A;  2YU9 A;  4LR2 A;  4P5A A;  4KAT A;  1HJK A;  5TMC A;  1TWA K;  2NVT C;  2W8D A;  1WSV A;  2R7Z K;  5IYB K;  1ANI A;  5IYC K;  5M5W K;  3GTM K;  4LQY A;  3AQP A;  1XXA A;  4A3G C;  3TX0 A;  3FOE A;  4O2D A;  1UV7 A;  4C2M K;  1Y1W K;  3GTL A;  3M4O K;  2W8S A;  2GAH C;  3GDZ A;  4A3E K;  1O26 A;  4GTW A;  4B56 A;  1ZVU A;  3FKI C;  1IS1 A;  2QZU A;  1J98 A;  1O2F B;  4A3F C;  3HOU K;  4CXK A;  4Q4Z A;  4YFK A;  1I50 C;  3FHZ A;  3OEP A;  3PO3 K;  3UN3 A;  1KH4 A;  3S16 C;  3S2D K;  1IE0 A;  3BDH A;  1PJ5 A;  1GE9 A;  5TMF A;  3I4M K;  1TWH C;  4C3H C;  4WJ4 A;  4DDQ A;  4C3I K;  4OIR A;  1VLO A;  3IPJ A;  3BDG A;  2NVQ C;  5C4X K;  5M3F K;  1JVI A;  5CJ9 A;  2G9Y A;  3M8W A;  4ZH4 A;  1SHN A;  4UOR A;  3S1N C;  2D1G A;  3GTK A;  5M5X K;  4QJV B;  1TWF C;  2E2H K;  1BJT A;  1TWC C;  3DXJ A;  4ZG7 A;  3A8J A;  3M8Y A;  3HKZ L;  1I3Q C;  4KN4 A;  3UO0 A;  4X6A C;  5IP7 K;  1B4B A;  1I6H K;  3QX3 A;  2IUC B;  5JVO A;  2W7V A;  1SMY A;  2R92 C;  3FOF A;  2W5R A;  2BE5 A;  5L46 A;  1AJD A;  5LRN A;  2JA6 C;  1J6V A;  1SHQ A;  3GTP A;  4A3D K;  1AJC A;  1WQH A;  1EJJ A;  1HQA A;  2NVX K;  4G7O A;  3S2H K;  2V6T A;  3Q3Q A;  1ZED A;  3S14 K;  2V6U A;  1TWG A;  1N2K A;  3AD9 C;  3HXA A;  2R93 C;  4GTD A;  3TFJ A;  4NWX A;  1URB A;  4NOI A;  2JA5 A;  1SFO K;  1K83 K;  3M7V A;  1DCO A;  1HQM A;  4G7H A;  2ZUE A;  3M8Z A;  1TWA C;  3NKM A;  1F93 A;  1XZP B;  2R7Z C;  2VQR A;  4KB2 A;  1WOO A;  5IYC C;  2XCO A;  3HKZ D;  4KJG A;  3GTM C;  3GTO K;  4LLG A;  4LRB A;  1F7U A;  1Y6V A;  3OT9 A;  2NVQ K;  3GTG K;  4JK1 A;  1BDF A;  1Y1W C;  4C2M C;  1ANJ A;  1R9T A;  3H0G A;  5KXA A;  3M4O C;  4GFQ A;  3BUE A;  4A3E C;  1Y1V C;  3RZD K;  4Q5S A;  2NVY K;  1KH9 A;  5D4D A;  5TJ3 A;  4BBR K;  4YR1 A;  4BY7 K;  3S15 K;  1EW2 A;  1KHJ A;  4XLP A;  2W5X A;  3HOU C;  3PO3 C;  2XRG A;  1N2L A;  3S2D C;  4BY1 K;  4XCH A;  1VJE A;  3I4M C;  2XCR B;  1USM A;  4QIW L;  1ELY A;  2O5I A;  2EBB A;  4GT9 A;  4C3I C;  3A52 A;  4QJV A;  3T00 A;  1C0A A;  5C4X C;  3UNY A;  3GEE A;  3CQZ K;  5EGE A;  2PHC B;  3MK0 A;  1WOS A;  3ORE A;  4GTZ A;  4AYB L;  2E2H C;  3NKO A;  1E2S P;  2IUC A;  3S1Q K;  5M5Y K;  4M1X A;  3TG0 A;  1ELX A;  2WB1 D;  5IP7 C;  4A3B K;  2IFY A;  4KN7 A;  1I6H C;  2CFA A;  3LAP A;  4G0V A;  5IYD K;  3HOW K;  2GLQ A;  2GA3 A;  2PA8 L;  4YG2 A;  1ELZ A;  3HOY K;  4KAV A;  2XR9 A;  1VH2 A;  1Y7A A;  4XSZ A;  3FKI A;  2O5J A;  2Y3P A;  1ALJ A;  3T02 A;  1YNJ A;  1EFW A;  4A3D C;  1ZYR A;  2NVX C;  3ADA C;  3VA7 A;  3GTQ A;  3S2H C;  4KM9 A;  1IQ0 A;  3S14 C;  1Y1V K;  4A93 K;  1TWH A;  3KD8 A;  5IOS A;  1XZP A;  1SFO C; 
#chains in the Genus database with same CATH homology
 1EQJ A;  4LRC A;  3SZZ A;  3E2D A;  4GTA A;  3ERE D;  1TWC A;  1I3Q A;  1O2B A;  1BGW A;  3WAW A;  3MML B;  3SZY A;  4CYR A;  2JA6 A;  1ED8 A;  1AJB A;  4GTC A;  3S0X A;  3IGY B;  1AJA A;  1EH1 A;  2R93 A;  3NKN A;  1AB4 A;  2ZKT A;  2CFA B;  1ALH A;  1ALK A;  1O25 A;  5IOQ A;  4G0W A;  4CXS A;  1KH7 A;  4ZG6 A;  3LPX A;  2R7Z A;  3GTM A;  1K7H A;  1KH5 A;  2W5T A;  1ISE A;  4UPH A;  1ED9 A;  4GTX A;  4MIV A;  3MK1 A;  3L4J A;  4UOP A;  1KHL A;  4ZGA A;  3V4G A;  1B8J A;  4KAS A;  5DLV A;  5AJ9 A;  4CXU A;  2GSU A;  2VUM A;  4TN0 A;  4KMD A;  4LRF A;  4LRE A;  5K4P A;  2E2H A;  2RGR A;  4FDI A;  3N3Y A;  3NVL A;  2KWA A;  1O2A A;  4MY4 A;  4NWJ A;  1O24 A;  3B5Q A;  4KAW X;  5EGH A;  3BDF A;  4UOO A;  1WIH A;  4G0U A;  4LR9 A;  4KDD A;  2NVX A;  4BLA A;  3NKR A;  1EW9 A;  4BKW A;  5L0E A;  1EI6 A;  2W5S A;  5HRT A;  1P49 A;  1FSU A;  3L4K A;  1SFO A;  1K83 A;  3AH5 A;  4GTE A;  4FDJ A;  1I50 A;  5GRR A;  3TWZ A;  3OPF A;  5DLT A;  2GSO A;  3GTO A;  1KHK A;  3WBH A;  3GTG A;  1E1Z P;  1O29 A;  3NKP A;  4UPL A;  4J3N A;  1XXB A;  1WQG A;  4LRA A;  5C66 A;  5INH A;  1TWF A;  4P5B A;  2NVY A;  5IJS A;  4GTF A;  5JFE A;  2W5V A;  5LRM A;  3AQO A;  2R92 A;  2X98 A;  2GSN A;  4N7T A;  4GTY A;  3CQZ A;  3DYC A;  1ZXO A;  3WAY A;  3N0C A;  4KC6 A;  1KQ4 A;  4UPK A;  3MK2 A;  4LR7 A;  3NUH A;  1KHN A;  3N0B A;  1EK8 A;  1TWA A;  1O99 A;  2XCQ A;  5IOT A;  3LAJ A;  4ZG9 A;  4KAR A;  5DLW A;  3WAV A;  5GOV A;  1Y1W A;  4KB4 A;  1Y1V A;  1WQF A;  1ZBS A;  4QAX A;  1O98 A;  4KM8 A;  2E2I A;  1WCM A;  1O28 A;  5IOR A;  4KM4 A;  3GTJ A;  5L0K A;  4KJD A;  3CAG A;  1XXC A;  3G4A A;  3NKQ A;  3DPC A;  1DD5 A;  1B4A A;  2B63 A;  2W5W A;  3ED4 A;  1ZEF A;  1ZEB A;  1E33 P;  2JA7 A;  2RH6 A;  3T01 A;  3CMR A;  1E3C P;  4MHX A;  1HDH A;  1O27 A;  2JH3 A;  2ANH A;  4KAY A;  4LRD A;  4GTB A;  4C3J C;  4ILD A;  3BDG B;  4KMA A;  4LR8 A;  4UPI A;  3IGZ B;  1F9N A;  3IDD A;  1ALI A;  2P5M A;  2W5Q A;  5LQQ A;  4CYS A;  5CHP A;  5L0B A;  1EW8 A;  1URA A;  1AUK A;  3UN2 A;  5IJQ A;  4BLB A;  4GTL A;  2ZFZ A;  3G4C A;  5LIA A;  4FM9 A;  3UN5 A;  4FZB A;  3LXQ A;  3WAX A;  4KMH A;  2YU9 A;  4LR2 A;  4P5A A;  4KAT A;  1HJK A;  2W8D A;  1ANI A;  4LQY A;  3AQP A;  1XXA A;  3TX0 A;  3FOE A;  3GTL A;  2W8S A;  1O26 A;  4GTW A;  4B56 A;  1ZVU A;  1IS1 A;  2QZU A;  4CXK A;  3FHZ A;  3OEP A;  3UN3 A;  1KH4 A;  3BDH A;  1GE9 A;  4C3H C;  4DDQ A;  3BDG A;  5CJ9 A;  3M8W A;  2G9Y A;  1SHN A;  4UOR A;  2D1G A;  3GTK A;  1BJT A;  4ZG7 A;  3M8Y A;  3UO0 A;  1B4B A;  3QX3 A;  2IUC B;  5JVO A;  3FOF A;  2W5R A;  1AJD A;  5LRN A;  1SHQ A;  3GTP A;  1HQA A;  1AJC A;  1WQH A;  1EJJ A;  3Q3Q A;  1ZED A;  1TWG A;  1N2K A;  4GTD A;  4NWX A;  1URB A;  2JA5 A;  3M7V A;  3M8Z A;  3NKM A;  2VQR A;  4KB2 A;  2XCO A;  4KJG A;  4LRB A;  1Y6V A;  3OT9 A;  5KXA A;  1ANJ A;  4C2M C;  1R9T A;  3H0G A;  4GFQ A;  3BUE A;  1KH9 A;  5TJ3 A;  4YR1 A;  1KHJ A;  1EW2 A;  2W5X A;  2XRG A;  1N2L A;  2XCR B;  1ELY A;  4GT9 A;  4C3I C;  3A52 A;  3T00 A;  3UNY A;  5EGE A;  2PHC B;  3MK0 A;  3ORE A;  4GTZ A;  3NKO A;  1E2S P;  2IUC A;  4M1X A;  3TG0 A;  1ELX A;  2IFY A;  2CFA A;  3LAP A;  4G0V A;  2GLQ A;  2GA3 A;  1ELZ A;  4KAV A;  2XR9 A;  1Y7A A;  3FKI A;  1ALJ A;  2Y3P A;  3T02 A;  3VA7 A;  3GTQ A;  4KM9 A;  1TWH A;  3KD8 A;  5IOS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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