4LR2A

Crystal structure of human enpp4 (apo)
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
Knots found
sequence length
379
structure length
379
Chain Sequence
LPPKLLLVSFDGFRADYLKNYEFPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDAVTKKHFSDSNDKDPFWWNEAVPIWVTNQLQENRSSAAAMWPGTDVPIHDTISSYFMNYNSSVSFEERLNNITMWLNNSNPPVTFATLYWEEPDASGHKYGPEDKENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSYYTLIDLSPVAAILPKINRTEVYNKLKNCSPHMNVYLKEDIPNRFYYQHNDRIQPIILVADEGWTIVLNESSQKLGDHGYDNSLPSMHPFLAAHGPAFHKGYKHSTINIVDIYPMMCHILGLKPHPNNGTFGHTKCLLVDQWCI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Molecular basis of purinergic signal metabolism by ectonucleotide pyrophosphatase/phosphodiesterases 4 and 1 and implications in stroke.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Bis(5'-adenosyl)-triphosphatase ENPP4
total genus 128
structure length 379
sequence length 379
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.6.1.29: Bis(5'-adenosyl)-triphosphatase.
pdb deposition date 2013-07-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.180 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Gyrase A; domain 2 4lr2A02
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4lr2A01
4ZG9A 3ED4A 3NKNA 1KHJA 3DPCA 3KD8A 4GTWA 5AJ9A 1KH9A 3E2DA 1Y6VA 4LR2A 5K4PA 3DYCA 3WAVA 3NKMA 4B56A 4LQYA 4UPKA 3NKOA 4UOOA 2XRGA 3OT9A 4ZG6A 1ALHA 4TN0A 3BDFA 3SZZA 4ZG7A 4LRBA 1HQAA 1KH4A 3M8YA 4FDJA 1EW9A 3T01A 3TWZA 1KH7A 4LRFA 3NKPA 1ANIA 1ELXA 3M8ZA 3WAYA 1ELYA 1Y7AA 1ZEFA 2W8SA 4GTZA 1B8JA 2RH6A 1URAA 2VQRA 3IGZB 1ED8A 5EGHA 1HDHA 5GRRA 3UN3A 1E33P 3T00A 4KJDA 3BDHA 4NWJA 1P49A 1ALKA 5EGEA 1FSUA 4CXUA 1O98A 2W5SA 4LR8A 3SZYA 3NVLA 3NKQA 1ELZA 4GTXA 4CYRA 1KH5A 3NKRA 5LRMA 2GSNA 1KHLA 4N7TA 5HRTA 4MIVA 5LIAA 1K7HA 4GTYA 2G9YA 2W5TA 5L0BA 3WBHA 3WAXA 4LRAA 3A52A 1AJAA 1N2KA 3WAWA 4UORA 1SHQA 3TG0A 5L0EA 3M8WA 1ALJA 3IGYB 5LQQA 2D1GA 2ANHA 4MY4A 1ZEDA 1EW8A 1ZEBA 3UO0A 1ED9A 2QZUA 1ALIA 3MK2A 5GOVA 4KAYA 4CYSA 4LRDA 4LRCA 2GSOA 4KJGA 5INHA 3MK0A 4CXKA 5TJ3A 4LR7A 5C66A 3B5QA 1EJJA 4KM4A 4UPHA 3UN5A 1E1ZP 2X98A 2XR9A 5DLVA 1HJKA 1KHKA 1E2SP 1EI6A 1N2LA 3MK1A 1KHNA 3CMRA 2W5WA 3UNYA 2W5QA 4LREA 1AJCA 1E3CP 2IUCB 2IUCA 4QAXA 2GLQA 1EQJA 4CXSA 4ZGAA 1ANJA 2GSUA 2IFYA 4KAVA 3T02A 3IDDA 5LRNA 4NWXA 5DLTA 2W5VA 2W8DA 3BDGA 3BDGB 5IJQA 1URBA 5DLWA 3M7VA 4UPLA 3Q3QA 5L0KA 3TX0A 1AJBA 5KXAA 3UN2A 4UOPA 4UPIA 2W5RA 1EW2A 4MHXA 4YR1A 2W5XA 3LXQA 2GA3A 5IJSA 2ZKTA 1AUKA 1O99A 4FDIA 1SHNA 4LR9A 1AJDA
chains in the Genus database with same CATH superfamily
3S14C 4BLAA 4GTWA 5CHPA 4C3JC 3E2DA 3DYCA 4WILA 3NKOA 4UOOA 2XRGA 2NVXK 3I4NK 1I6HK 5HL8A 2P5MA 3A8IA 3TFIA 1HQAA 4OINA 4GTDA 4FDJA 3ERED 3AH5A 4ILDA 3PO2K 3N0BA 1WIHA 4A3EC 4PAAA 1DCHA 3NKPA 1ANIA 2XCQA 1F7VA 3HOVK 1ELXA 2V6UA 1Y7AA 1ZEFA 4C2MK 1B4AA 1IE0A 1TWFC 2RH6A 1TWFA 4GTCA 4XSZA 3IGZB 4AH6A 1ZYRA 3TFJA 3GTKK 2NVYC 2NVYA 5EGHA 5IYDK 3AD7C 1J98A 2NVTK 1HQMA 3T00A 2E2IK 4A3JC 4KARA 3GTOK 1J6XA 3OREA 1ALKA 1IW7A 1P49A 4LJZA 4Y7NC 1ISEA 4CXUA 2GSNA 3S0XA 2JA5K 4MIVA 5LIAA 4G7HA 5IOTA 5L0BA 4C3HC 3WAXA 3A52A 4UORA 4YG2A 2O5IA 3IGYB 1AB4A 4Y52C 4WJ4A 2D1GA 3S1QK 1O25A 2E2JK 1X31C 2JA8K 3S2HK 3MK0A 4G0UA 1EJJA 2XCRB 5TMFA 4KM4A 4QJVA 1E1ZP 1JVIA 1O24A 2VUMK 1F9NA 2FQOA 4A93C 1VRQC 4KMUA 2V6TA 1KHNA 3K7AK 1XZQB 3L4JA 1AJCA 1E3CP 4QAXA 2NVXA 3GDZA 1I6HC 3A8KA 4GTAA 4CXSA 1WQHA 3RZOC 1ZQ1C 1ANJA 2GSUA 3PO2C 3IDDA 1WQFA 3G4CA 4BXXC 1TWFK 2W5VA 3HOVC 2W8DA 3BDGB 4C2MC 4P5AA 1VLOA 5DLWA 2NVYK 1JQWA 3M7VA 3HXAA 1K83K 2RGRA 3HOUC 2KWAA 4UPLA 1EH1A 3GTKC 3GTKA 2Y3PA 4UOPA 1B4BA 5E68A 4A3JK 4GTFA 5IOQA 1UV7A 2P8TA 4GTLA 5IP7C 2W5XA 3LXQA 1O27A 2E2IC 2E2IA 3AD9C 3GTOC 3VA7A 3GTOA 1AUKA 5FLMC 1TWHC 4O2DA 1AJDA 1TWHA 3JSTA 2W7VA 4LK1A 4DDQA 1KHJA 3HKZL 4LR2A 1ZXOA 4B56A 4C3HK 3FOEA 4UPKA 4TN0A 3S17C 4ZG7A 1YCLA 4LRBA 4A3KC 5M3MK 1KH4A 3M8YA 1O26A 3TFHA 3GTLK 3S1QC 3WAYA 2W8SA 4GTZA 4J3NA 1B8JA 2E2HK 3GTPC 5M5XK 3GTPA 1YNJA 4FZBA 5GRRA 1E33P 4KM9A 2D6FC 1TWGK 1DCPA 3LAPA 3BDHA 4A93K 4NWJA 2VUMC 2VUMA 2W5SA 1L0WA 3K7AC 2WB1D 4OIOA 4GFQA 4G0WA 3RZOK 1KH5A 1R9TC 3V4GA 1R9TA 3TTGA 4BBSK 1K7HA 2A6EA 2WB1L 3H0GK 1USMA 4X6AC 2W5TA 4BXXK 4KMHA 3WBHA 3S1MC 3GTJK 4KN7A 3S2DC 4LK0A 3GIRA 3G4AA 3MMLB 4C45A 5C44K 1N2KA 1J6VA 1SHQA 2B63K 3TG0A 3HOUK 5L0EA 4PABA 4MEYA 1RU0A 1K83C 5C4XK 1F7UA 1K83A 4A3BC 1JOEA 1ZEDA 1EW8A 5IP7K 5CJ9A 1ALIA 4CYSA 5IYCC 5GOVA 5L46A 3ADAC 4LRDA 1WOOA 4A3GK 2A69A 4LRCA 4KJGA 4A3CC 5FLMK 1TWHK 1I3QK 4LR7A 3OPFA 3S1NK 3UN5A 2X98A 2NVQK 5IP9C 1E2SP 1PJ7A 1XZPB 2FQTA 2EBBA 3I4MK 2O5JA 1IL2A 2W5WA 3S17K 3M4OC 1XZQA 4M1XA 4A3KK 1XXCA 2IUCB 1G51A 2PA8D 2R92C 2R7ZK 4ZGAA 1WSRA 3DXJA 2IFYA 1WOPA 2PA8L 3T02A 4KAVA 3GTLC 3IPJA 3GTLA 1WQGA 5DLTA 3BDGA 1VH2A 3N3YA 3GTPK 4OIPA 3NUHA 4GT9A 3TX0A 2E2HC 5KXAA 2E2HA 3OEPA 3HOXK 4LOWA 1EW2A 4YR1A 2PPBA 1WORA 1TWGC 1XXAA 1TWGA 4NOIA 4GZYA 4A3LK 1O99A 1ZVUA 1SHNA 1R9TK 1TWCK 1O29A 3S16K 3NKNA 4YFNA 3DPCA 3KD8A 5AJ9A 4X6AK 2WAQD 1SFOK 1Y6VA 4XSXA 4BBSC 3S1MK 3WAVA 1PJ6A 3H0GC 1WOSA 4LQYA 3H0GA 3S2DK 4G7OA 1GE9A 2WAQL 3GTJC 2CW0A 4BBRC 3GTJA 1O28A 5C44C 2ZUEA 4AYBD 2B63C 1Y1WC 1DCOA 5IORA 1Y1WA 4A3BK 2B63A 1O2AA 1EW9A 1KH7A 3TWZA 1VGXA 4AYBL 5C4XC 5IYCK 4KAWX 1IQ0A 4ZH4A 1IBAA 4A3CK 2VQRA 4XLNA 3CQZC 4A3GC 1ED8A 3HKZD 1I3QC 1HI9A 1I3QA 2ZFZA 3LAJA 5IP9K 5C4JC 3S1NC 1F93A 2NVQC 3M4OK 1FSUA 5JVOA 3I4MC 3NKQA 1ELZA 4GTXA 3BUEA 1INNA 5IYBC 2R92K 3GEIA 3BP8C 3M3YC 4GTBA 1KHLA 3GEEA 1BJTA 2R7ZC 1BS2A 2R7ZA 5TMCA 1O2BA 3HOZC 4KC6A 5M5WK 4LRAA 3WAWA 3HOYC 1ALJA 1USOA 2BE5A 5FJ8K 1I6VA 4OIQA 2XCOA 3UO0A 1ED9A 3HOXC 4KATA 2CFAB 2QZUA 3MK2A 4KAYA 4KB4A 3FHZA 1EFWA 1ZBSA 2GSOA 5INHA 4LLGA 4A3LC 4CXKA 3AQPA 1SMYA 5C66A 3B5QA 1TWCC 1TWCA 3S16C 2ZUFA 2V6SA 4JK1A 2JA6K 1EI6A 1XZPA 1SFOC 1SFOA 4Q4ZA 3UNYA 4BBRK 3PO3C 2W5QA 4LREA 2IUCA 1Y1WK 3S1RK 4C3IK 2R93C 3HOWK 2R93A 1O2FB 3AQOA 3FKIK 4NWXA 4BY7C 3RZDC 1URBA 1J6WA 2PHCB 3CQZK 4A3IC 3GTQK 4OIRA 4MEXA 1DD5A 4A3DK 5L0KA 4RMFA 3FOFA 5C4JK 2W5RA 1Y1VK 1WCMK 3AD8C 4KN4A 1V5VA 5IJSA 4KB2A 5IYBK 4FDIA 4KASA 4ZG9A 1YNNA 3ED4A 3M3YK 2R92A 3L4KA 5IOSA 4YFXA 2A68A 3GTMC 3GTMA 4GTEA 1KH9A 5K4PA 3HOZK 3NKMA 2JH3A 3OT9A 3HOYK 4ZG6A 1IS1A 1ALHA 3S15K 3BDFA 4BY1C 3SZZA 1XXBA 2GAHC 5C3EK 5M5YK 5JFEA 4MQ9A 3T01A 4LRFA 1KQ4A 4BKWA 2YU9K 1C0AA 4A3MK 3M8ZA 1ELYA 3GTGK 1URAA 3H3VD 5D4DA 2JA7C 2JA7A 1I50K 1WSVA 1HDHA 1BGWA 3UN3A 4P5BA 3H3VL 4FM9A 3EQLA 4KJDA 1TWAC 1TWAA 3N0CA 5EGEA 2GAGC 3PO3K 3SZYA 4YFKA 4A3FC 2JA6C 2JA6A 1O98A 3S14K 3NVLA 4LR8A 4CYRA 4BLBA 3NKRA 2R93K 5LRMA 4C3JK 3S1RC 4N7TA 5HRTA 4C3IC 4GTYA 2G9YA 3HOWC 4G0VA 4BY7K 4XCHA 1PJ5A 3RZDK 3FKIC 3FKIA 1AJAA 4A3IK 2NVXC 3I4NC 3LPXA 3GSIA 3M8WA 3WODA 4A3EK 3CQZA 3GTQC 3GTQA 1EK8A 4QIWD 5LQQA 2ANHA 4A3DC 4MY4A 1BDFA 4KMDA 1ZEBA 3A8JA 1Y1VC 1WCMC 4QIWL 1Y1VA 1WCMA 2CFAA 2PMZD 4Q5SA 4KM8A 2Y0SD 4XLPA 2PMZL 2A6HA 5TJ3A 5IYDC 2Y0SL 3GTMK 4QJVB 4UPHA 1VJEA 4KMAA 2XR9A 2NVTC 5DLVA 1HJKA 1KHKA 4Y7NK 1N2LA 4G7ZA 3MK1A 3CAGA 3CMRA 4BY1K 4P9SA 2GLQA 1EQJA 3S15C 3GEHA 5C3EC 5M3FK 2JA5C 1EQRA 1XPPA 2JA5A 5LRNA 2YU9C 2YU9A 5IJQA 4A3MC 2JA7K 3GTGC 3GTGA 4Y52K 3Q3QA 1AJBA 3UN2A 1I50C 1YX2A 1I50A 4WJ3M 4UPIA 1TWAK 4MHXA 2GA3A 3BP3A 2ZKTA 4A3FK 2E2JC 4KDDA 2JA8C 3S2HC 3QX3A 4LR9A
chains in the Genus database with same CATH topology
4BLAA 4GTWA 5CHPA 4C3JC 3E2DA 3DYCA 3NKOA 4UOOA 2XRGA 2P5MA 1HQAA 4GTDA 4FDJA 3ERED 3AH5A 4ILDA 3N0BA 1WIHA 3NKPA 1ANIA 2XCQA 1ELXA 1Y7AA 1ZEFA 1B4AA 2RH6A 1TWFA 4GTCA 3IGZB 2NVYA 5EGHA 3T00A 4KARA 3OREA 1ALKA 1P49A 1ISEA 4CXUA 2GSNA 3S0XA 4MIVA 5LIAA 5IOTA 5L0BA 4C3HC 3WAXA 3A52A 4UORA 3IGYB 1AB4A 2D1GA 1O25A 3MK0A 4G0UA 1EJJA 2XCRB 4KM4A 1E1ZP 1O24A 1F9NA 1KHNA 3L4JA 1AJCA 1E3CP 4QAXA 2NVXA 4GTAA 4CXSA 1WQHA 1ANJA 2GSUA 3IDDA 1WQFA 3G4CA 2W5VA 2W8DA 3BDGB 4C2MC 4P5AA 5DLWA 3M7VA 2RGRA 4UPLA 2KWAA 1EH1A 3GTKA 2Y3PA 4UOPA 1B4BA 4GTFA 5IOQA 4GTLA 2W5XA 3LXQA 1O27A 2E2IA 3VA7A 3GTOA 1AUKA 1AJDA 1TWHA 4DDQA 1KHJA 4LR2A 1ZXOA 4B56A 3FOEA 4UPKA 4TN0A 4ZG7A 4LRBA 1KH4A 3M8YA 1O26A 3WAYA 2W8SA 4GTZA 4J3NA 1B8JA 3GTPA 5GRRA 4FZBA 1E33P 4KM9A 3LAPA 3BDHA 4NWJA 2VUMA 2W5SA 4GFQA 4G0WA 1KH5A 3V4GA 1R9TA 1K7HA 2W5TA 3WBHA 4KMHA 3G4AA 3MMLB 1N2KA 1SHQA 3TG0A 5L0EA 1K83A 1ZEDA 1EW8A 5CJ9A 1ALIA 4CYSA 5GOVA 4LRDA 4LRCA 4KJGA 4LR7A 3OPFA 3UN5A 2X98A 1E2SP 2W5WA 4M1XA 2IUCB 1XXCA 4ZGAA 2IFYA 4KAVA 3T02A 3GTLA 1WQGA 5DLTA 3BDGA 3N3YA 3NUHA 4GT9A 3TX0A 5KXAA 2E2HA 3OEPA 1EW2A 4YR1A 1XXAA 1TWGA 1O99A 1ZVUA 1SHNA 1O29A 3NKNA 3DPCA 3KD8A 5AJ9A 1Y6VA 3WAVA 4LQYA 3H0GA 1GE9A 3GTJA 1O28A 2B63A 5IORA 1Y1WA 1EW9A 1KH7A 1O2AA 3TWZA 4KAWX 2VQRA 1ED8A 1I3QA 3LAJA 2ZFZA 1FSUA 5JVOA 3NKQA 1ELZA 4GTXA 3BUEA 4GTBA 1KHLA 1BJTA 2R7ZA 1O2BA 4KC6A 4LRAA 3WAWA 1ALJA 2XCOA 3UO0A 1ED9A 4KATA 2CFAB 2QZUA 3MK2A 4KAYA 4KB4A 3FHZA 1ZBSA 2GSOA 5INHA 4CXKA 3AQPA 5C66A 3B5QA 1TWCA 1EI6A 1SFOA 3UNYA 2W5QA 4LREA 2IUCA 2R93A 3AQOA 4NWXA 1URBA 2PHCB 1DD5A 5L0KA 3FOFA 2W5RA 5IJSA 4KB2A 4FDIA 4KASA 4ZG9A 3ED4A 2R92A 3L4KA 5IOSA 3GTMA 4GTEA 1KH9A 5K4PA 3NKMA 2JH3A 3OT9A 4ZG6A 1IS1A 1ALHA 3BDFA 3SZZA 1XXBA 5JFEA 3T01A 4LRFA 1KQ4A 4BKWA 3M8ZA 1ELYA 1URAA 2JA7A 1HDHA 1BGWA 3UN3A 4P5BA 4FM9A 4KJDA 1TWAA 3N0CA 5EGEA 1O98A 3SZYA 4LR8A 2JA6A 3NVLA 4CYRA 4BLBA 3NKRA 5LRMA 4N7TA 5HRTA 4C3IC 4GTYA 2G9YA 4G0VA 3FKIA 1AJAA 3LPXA 3M8WA 3CQZA 3GTQA 1EK8A 5LQQA 2ANHA 4MY4A 4KMDA 1ZEBA 1Y1VA 1WCMA 2CFAA 4KM8A 5TJ3A 4UPHA 4KMAA 2XR9A 5DLVA 1HJKA 1KHKA 1N2LA 3MK1A 3CAGA 3CMRA 2GLQA 1EQJA 2JA5A 5LRNA 2YU9A 5IJQA 3GTGA 3Q3QA 1AJBA 3UN2A 1I50A 4UPIA 4MHXA 2GA3A 2ZKTA 4KDDA 3QX3A 4LR9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZG9 A;  3ED4 A;  3NKN A;  1KHJ A;  3DPC A;  3KD8 A;  4GTW A;  5AJ9 A;  1KH9 A;  3E2D A;  1Y6V A;  4LR2 A;  5K4P A;  3DYC A;  3WAV A;  3NKM A;  4B56 A;  4LQY A;  4UPK A;  3NKO A;  4UOO A;  2XRG A;  3OT9 A;  4ZG6 A;  1ALH A;  4TN0 A;  3BDF A;  3SZZ A;  4ZG7 A;  4LRB A;  1HQA A;  1KH4 A;  3M8Y A;  4FDJ A;  1EW9 A;  3T01 A;  3TWZ A;  1KH7 A;  4LRF A;  3NKP A;  1ANI A;  1ELX A;  3M8Z A;  3WAY A;  1ELY A;  1Y7A A;  1ZEF A;  2W8S A;  4GTZ A;  1B8J A;  2RH6 A;  1URA A;  2VQR A;  3IGZ B;  1ED8 A;  5EGH A;  1HDH A;  5GRR A;  3UN3 A;  1E33 P;  3T00 A;  4KJD A;  3BDH A;  4NWJ A;  1P49 A;  1ALK A;  5EGE A;  1FSU A;  4CXU A;  1O98 A;  2W5S A;  4LR8 A;  3SZY A;  3NVL A;  3NKQ A;  1ELZ A;  4GTX A;  4CYR A;  1KH5 A;  3NKR A;  5LRM A;  2GSN A;  1KHL A;  4N7T A;  5HRT A;  4MIV A;  5LIA A;  1K7H A;  4GTY A;  2G9Y A;  2W5T A;  5L0B A;  3WBH A;  3WAX A;  4LRA A;  3A52 A;  1AJA A;  1N2K A;  3WAW A;  4UOR A;  1SHQ A;  3TG0 A;  5L0E A;  3M8W A;  1ALJ A;  3IGY B;  5LQQ A;  2D1G A;  2ANH A;  4MY4 A;  1ZED A;  1EW8 A;  1ZEB A;  3UO0 A;  1ED9 A;  2QZU A;  1ALI A;  3MK2 A;  5GOV A;  4KAY A;  4CYS A;  4LRD A;  4LRC A;  2GSO A;  4KJG A;  5INH A;  3MK0 A;  4CXK A;  5TJ3 A;  4LR7 A;  5C66 A;  3B5Q A;  1EJJ A;  4KM4 A;  4UPH A;  3UN5 A;  1E1Z P;  2X98 A;  2XR9 A;  5DLV A;  1HJK A;  1KHK A;  1E2S P;  1EI6 A;  1N2L A;  3MK1 A;  1KHN A;  3CMR A;  2W5W A;  3UNY A;  2W5Q A;  4LRE A;  1AJC A;  1E3C P;  2IUC B;  2IUC A;  4QAX A;  2GLQ A;  1EQJ A;  4CXS A;  4ZGA A;  1ANJ A;  2GSU A;  2IFY A;  4KAV A;  3T02 A;  3IDD A;  5LRN A;  4NWX A;  5DLT A;  2W5V A;  2W8D A;  3BDG A;  3BDG B;  5IJQ A;  1URB A;  5DLW A;  3M7V A;  4UPL A;  3Q3Q A;  5L0K A;  3TX0 A;  1AJB A;  5KXA A;  3UN2 A;  4UOP A;  4UPI A;  2W5R A;  1EW2 A;  4MHX A;  4YR1 A;  2W5X A;  3LXQ A;  2GA3 A;  5IJS A;  2ZKT A;  1AUK A;  1O99 A;  4FDI A;  1SHN A;  4LR9 A;  1AJD A; 
#chains in the Genus database with same CATH topology
 3S14 C;  4BLA A;  4GTW A;  5CHP A;  4C3J C;  3E2D A;  3DYC A;  4WIL A;  3NKO A;  4UOO A;  2XRG A;  2NVX K;  3I4N K;  1I6H K;  5HL8 A;  2P5M A;  3A8I A;  3TFI A;  1HQA A;  4OIN A;  4GTD A;  4FDJ A;  3ERE D;  3AH5 A;  4ILD A;  3PO2 K;  3N0B A;  1WIH A;  4A3E C;  4PAA A;  1DCH A;  3NKP A;  1ANI A;  2XCQ A;  1F7V A;  3HOV K;  1ELX A;  2V6U A;  1Y7A A;  1ZEF A;  4C2M K;  1B4A A;  1IE0 A;  1TWF C;  2RH6 A;  1TWF A;  4GTC A;  4XSZ A;  3IGZ B;  4AH6 A;  1ZYR A;  3TFJ A;  3GTK K;  2NVY C;  2NVY A;  5EGH A;  5IYD K;  3AD7 C;  1J98 A;  2NVT K;  1HQM A;  3T00 A;  2E2I K;  4A3J C;  4KAR A;  3GTO K;  1J6X A;  3ORE A;  1ALK A;  1IW7 A;  1P49 A;  4LJZ A;  4Y7N C;  1ISE A;  4CXU A;  2GSN A;  3S0X A;  2JA5 K;  4MIV A;  5LIA A;  4G7H A;  5IOT A;  5L0B A;  4C3H C;  3WAX A;  3A52 A;  4UOR A;  4YG2 A;  2O5I A;  3IGY B;  1AB4 A;  4Y52 C;  4WJ4 A;  2D1G A;  3S1Q K;  1O25 A;  2E2J K;  1X31 C;  2JA8 K;  3S2H K;  3MK0 A;  4G0U A;  1EJJ A;  2XCR B;  5TMF A;  4KM4 A;  4QJV A;  1E1Z P;  1JVI A;  1O24 A;  2VUM K;  1F9N A;  2FQO A;  4A93 C;  1VRQ C;  4KMU A;  2V6T A;  1KHN A;  3K7A K;  1XZQ B;  3L4J A;  1AJC A;  1E3C P;  4QAX A;  2NVX A;  3GDZ A;  1I6H C;  3A8K A;  4GTA A;  4CXS A;  1WQH A;  3RZO C;  1ZQ1 C;  1ANJ A;  2GSU A;  3PO2 C;  3IDD A;  1WQF A;  3G4C A;  4BXX C;  1TWF K;  2W5V A;  3HOV C;  2W8D A;  3BDG B;  4C2M C;  4P5A A;  1VLO A;  5DLW A;  2NVY K;  1JQW A;  3M7V A;  3HXA A;  1K83 K;  2RGR A;  3HOU C;  2KWA A;  4UPL A;  1EH1 A;  3GTK C;  3GTK A;  2Y3P A;  4UOP A;  1B4B A;  5E68 A;  4A3J K;  4GTF A;  5IOQ A;  1UV7 A;  2P8T A;  4GTL A;  5IP7 C;  2W5X A;  3LXQ A;  1O27 A;  2E2I C;  2E2I A;  3AD9 C;  3GTO C;  3VA7 A;  3GTO A;  1AUK A;  5FLM C;  1TWH C;  4O2D A;  1AJD A;  1TWH A;  3JST A;  2W7V A;  4LK1 A;  4DDQ A;  1KHJ A;  3HKZ L;  4LR2 A;  1ZXO A;  4B56 A;  4C3H K;  3FOE A;  4UPK A;  4TN0 A;  3S17 C;  4ZG7 A;  1YCL A;  4LRB A;  4A3K C;  5M3M K;  1KH4 A;  3M8Y A;  1O26 A;  3TFH A;  3GTL K;  3S1Q C;  3WAY A;  2W8S A;  4GTZ A;  4J3N A;  1B8J A;  2E2H K;  3GTP C;  5M5X K;  3GTP A;  1YNJ A;  4FZB A;  5GRR A;  1E33 P;  4KM9 A;  2D6F C;  1TWG K;  1DCP A;  3LAP A;  3BDH A;  4A93 K;  4NWJ A;  2VUM C;  2VUM A;  2W5S A;  1L0W A;  3K7A C;  2WB1 D;  4OIO A;  4GFQ A;  4G0W A;  3RZO K;  1KH5 A;  1R9T C;  3V4G A;  1R9T A;  3TTG A;  4BBS K;  1K7H A;  2A6E A;  2WB1 L;  3H0G K;  1USM A;  4X6A C;  2W5T A;  4BXX K;  4KMH A;  3WBH A;  3S1M C;  3GTJ K;  4KN7 A;  3S2D C;  4LK0 A;  3GIR A;  3G4A A;  3MML B;  4C45 A;  5C44 K;  1N2K A;  1J6V A;  1SHQ A;  2B63 K;  3TG0 A;  3HOU K;  5L0E A;  4PAB A;  4MEY A;  1RU0 A;  1K83 C;  5C4X K;  1F7U A;  1K83 A;  4A3B C;  1JOE A;  1ZED A;  1EW8 A;  5IP7 K;  5CJ9 A;  1ALI A;  4CYS A;  5IYC C;  5GOV A;  5L46 A;  3ADA C;  4LRD A;  1WOO A;  4A3G K;  2A69 A;  4LRC A;  4KJG A;  4A3C C;  5FLM K;  1TWH K;  1I3Q K;  4LR7 A;  3OPF A;  3S1N K;  3UN5 A;  2X98 A;  2NVQ K;  5IP9 C;  1E2S P;  1PJ7 A;  1XZP B;  2FQT A;  2EBB A;  3I4M K;  2O5J A;  1IL2 A;  2W5W A;  3S17 K;  3M4O C;  1XZQ A;  4M1X A;  4A3K K;  1XXC A;  2IUC B;  1G51 A;  2PA8 D;  2R92 C;  2R7Z K;  4ZGA A;  1WSR A;  3DXJ A;  2IFY A;  1WOP A;  2PA8 L;  3T02 A;  4KAV A;  3GTL C;  3IPJ A;  3GTL A;  1WQG A;  5DLT A;  3BDG A;  1VH2 A;  3N3Y A;  3GTP K;  4OIP A;  3NUH A;  4GT9 A;  3TX0 A;  2E2H C;  5KXA A;  2E2H A;  3OEP A;  3HOX K;  4LOW A;  1EW2 A;  4YR1 A;  2PPB A;  1WOR A;  1TWG C;  1XXA A;  1TWG A;  4NOI A;  4GZY A;  4A3L K;  1O99 A;  1ZVU A;  1SHN A;  1R9T K;  1TWC K;  1O29 A;  3S16 K;  3NKN A;  4YFN A;  3DPC A;  3KD8 A;  5AJ9 A;  4X6A K;  2WAQ D;  1SFO K;  1Y6V A;  4XSX A;  4BBS C;  3S1M K;  3WAV A;  1PJ6 A;  3H0G C;  1WOS A;  4LQY A;  3H0G A;  3S2D K;  4G7O A;  1GE9 A;  2WAQ L;  3GTJ C;  2CW0 A;  4BBR C;  3GTJ A;  1O28 A;  5C44 C;  2ZUE A;  4AYB D;  2B63 C;  1Y1W C;  1DCO A;  5IOR A;  1Y1W A;  4A3B K;  2B63 A;  1O2A A;  1EW9 A;  1KH7 A;  3TWZ A;  1VGX A;  4AYB L;  5C4X C;  5IYC K;  4KAW X;  1IQ0 A;  4ZH4 A;  1IBA A;  4A3C K;  2VQR A;  4XLN A;  3CQZ C;  4A3G C;  1ED8 A;  3HKZ D;  1I3Q C;  1HI9 A;  1I3Q A;  2ZFZ A;  3LAJ A;  5IP9 K;  5C4J C;  3S1N C;  1F93 A;  2NVQ C;  3M4O K;  1FSU A;  5JVO A;  3I4M C;  3NKQ A;  1ELZ A;  4GTX A;  3BUE A;  1INN A;  5IYB C;  2R92 K;  3GEI A;  3BP8 C;  3M3Y C;  4GTB A;  1KHL A;  3GEE A;  1BJT A;  2R7Z C;  1BS2 A;  2R7Z A;  5TMC A;  1O2B A;  3HOZ C;  4KC6 A;  5M5W K;  4LRA A;  3WAW A;  3HOY C;  1ALJ A;  1USO A;  2BE5 A;  5FJ8 K;  1I6V A;  4OIQ A;  2XCO A;  3UO0 A;  1ED9 A;  3HOX C;  4KAT A;  2CFA B;  2QZU A;  3MK2 A;  4KAY A;  4KB4 A;  3FHZ A;  1EFW A;  1ZBS A;  2GSO A;  5INH A;  4LLG A;  4A3L C;  4CXK A;  3AQP A;  1SMY A;  5C66 A;  3B5Q A;  1TWC C;  1TWC A;  3S16 C;  2ZUF A;  2V6S A;  4JK1 A;  2JA6 K;  1EI6 A;  1XZP A;  1SFO C;  1SFO A;  4Q4Z A;  3UNY A;  4BBR K;  3PO3 C;  2W5Q A;  4LRE A;  2IUC A;  1Y1W K;  3S1R K;  4C3I K;  2R93 C;  3HOW K;  2R93 A;  1O2F B;  3AQO A;  3FKI K;  4NWX A;  4BY7 C;  3RZD C;  1URB A;  1J6W A;  2PHC B;  3CQZ K;  4A3I C;  3GTQ K;  4OIR A;  4MEX A;  1DD5 A;  4A3D K;  5L0K A;  4RMF A;  3FOF A;  5C4J K;  2W5R A;  1Y1V K;  1WCM K;  3AD8 C;  4KN4 A;  1V5V A;  5IJS A;  4KB2 A;  5IYB K;  4FDI A;  4KAS A;  4ZG9 A;  1YNN A;  3ED4 A;  3M3Y K;  2R92 A;  3L4K A;  5IOS A;  4YFX A;  2A68 A;  3GTM C;  3GTM A;  4GTE A;  1KH9 A;  5K4P A;  3HOZ K;  3NKM A;  2JH3 A;  3OT9 A;  3HOY K;  4ZG6 A;  1IS1 A;  1ALH A;  3S15 K;  3BDF A;  4BY1 C;  3SZZ A;  1XXB A;  2GAH C;  5C3E K;  5M5Y K;  5JFE A;  4MQ9 A;  3T01 A;  4LRF A;  1KQ4 A;  4BKW A;  2YU9 K;  1C0A A;  4A3M K;  3M8Z A;  1ELY A;  3GTG K;  1URA A;  3H3V D;  5D4D A;  2JA7 C;  2JA7 A;  1I50 K;  1WSV A;  1HDH A;  1BGW A;  3UN3 A;  4P5B A;  3H3V L;  4FM9 A;  3EQL A;  4KJD A;  1TWA C;  1TWA A;  3N0C A;  5EGE A;  2GAG C;  3PO3 K;  3SZY A;  4YFK A;  4A3F C;  2JA6 C;  2JA6 A;  1O98 A;  3S14 K;  3NVL A;  4LR8 A;  4CYR A;  4BLB A;  3NKR A;  2R93 K;  5LRM A;  4C3J K;  3S1R C;  4N7T A;  5HRT A;  4C3I C;  4GTY A;  2G9Y A;  3HOW C;  4G0V A;  4BY7 K;  4XCH A;  1PJ5 A;  3RZD K;  3FKI C;  3FKI A;  1AJA A;  4A3I K;  2NVX C;  3I4N C;  3LPX A;  3GSI A;  3M8W A;  3WOD A;  4A3E K;  3CQZ A;  3GTQ C;  3GTQ A;  1EK8 A;  4QIW D;  5LQQ A;  2ANH A;  4A3D C;  4MY4 A;  1BDF A;  4KMD A;  1ZEB A;  3A8J A;  1Y1V C;  1WCM C;  4QIW L;  1Y1V A;  1WCM A;  2CFA A;  2PMZ D;  4Q5S A;  4KM8 A;  2Y0S D;  4XLP A;  2PMZ L;  2A6H A;  5TJ3 A;  5IYD C;  2Y0S L;  3GTM K;  4QJV B;  4UPH A;  1VJE A;  4KMA A;  2XR9 A;  2NVT C;  5DLV A;  1HJK A;  1KHK A;  4Y7N K;  1N2L A;  4G7Z A;  3MK1 A;  3CAG A;  3CMR A;  4BY1 K;  4P9S A;  2GLQ A;  1EQJ A;  3S15 C;  3GEH A;  5C3E C;  5M3F K;  2JA5 C;  1EQR A;  1XPP A;  2JA5 A;  5LRN A;  2YU9 C;  2YU9 A;  5IJQ A;  4A3M C;  2JA7 K;  3GTG C;  3GTG A;  4Y52 K;  3Q3Q A;  1AJB A;  3UN2 A;  1I50 C;  1YX2 A;  1I50 A;  4WJ3 M;  4UPI A;  1TWA K;  4MHX A;  2GA3 A;  3BP3 A;  2ZKT A;  4A3F K;  2E2J C;  4KDD A;  2JA8 C;  3S2H C;  3QX3 A;  4LR9 A; 
#chains in the Genus database with same CATH homology
 4BLA A;  4GTW A;  5CHP A;  4C3J C;  3E2D A;  3DYC A;  3NKO A;  4UOO A;  2XRG A;  2P5M A;  1HQA A;  4GTD A;  4FDJ A;  3ERE D;  3AH5 A;  4ILD A;  3N0B A;  1WIH A;  3NKP A;  1ANI A;  2XCQ A;  1ELX A;  1Y7A A;  1ZEF A;  1B4A A;  2RH6 A;  1TWF A;  4GTC A;  3IGZ B;  2NVY A;  5EGH A;  3T00 A;  4KAR A;  3ORE A;  1ALK A;  1P49 A;  1ISE A;  4CXU A;  2GSN A;  3S0X A;  4MIV A;  5LIA A;  5IOT A;  5L0B A;  4C3H C;  3WAX A;  3A52 A;  4UOR A;  3IGY B;  1AB4 A;  2D1G A;  1O25 A;  3MK0 A;  4G0U A;  1EJJ A;  2XCR B;  4KM4 A;  1E1Z P;  1O24 A;  1F9N A;  1KHN A;  3L4J A;  1AJC A;  1E3C P;  4QAX A;  2NVX A;  4GTA A;  4CXS A;  1WQH A;  1ANJ A;  2GSU A;  3IDD A;  1WQF A;  3G4C A;  2W5V A;  2W8D A;  3BDG B;  4C2M C;  4P5A A;  5DLW A;  3M7V A;  2RGR A;  4UPL A;  2KWA A;  1EH1 A;  3GTK A;  2Y3P A;  4UOP A;  1B4B A;  4GTF A;  5IOQ A;  4GTL A;  2W5X A;  3LXQ A;  1O27 A;  2E2I A;  3VA7 A;  3GTO A;  1AUK A;  1AJD A;  1TWH A;  4DDQ A;  1KHJ A;  4LR2 A;  1ZXO A;  4B56 A;  3FOE A;  4UPK A;  4TN0 A;  4ZG7 A;  4LRB A;  1KH4 A;  3M8Y A;  1O26 A;  3WAY A;  2W8S A;  4GTZ A;  4J3N A;  1B8J A;  3GTP A;  5GRR A;  4FZB A;  1E33 P;  4KM9 A;  3LAP A;  3BDH A;  4NWJ A;  2VUM A;  2W5S A;  4GFQ A;  4G0W A;  1KH5 A;  3V4G A;  1R9T A;  1K7H A;  2W5T A;  3WBH A;  4KMH A;  3G4A A;  3MML B;  1N2K A;  1SHQ A;  3TG0 A;  5L0E A;  1K83 A;  1ZED A;  1EW8 A;  5CJ9 A;  1ALI A;  4CYS A;  5GOV A;  4LRD A;  4LRC A;  4KJG A;  4LR7 A;  3OPF A;  3UN5 A;  2X98 A;  1E2S P;  2W5W A;  4M1X A;  2IUC B;  1XXC A;  4ZGA A;  2IFY A;  4KAV A;  3T02 A;  3GTL A;  1WQG A;  5DLT A;  3BDG A;  3N3Y A;  3NUH A;  4GT9 A;  3TX0 A;  5KXA A;  2E2H A;  3OEP A;  1EW2 A;  4YR1 A;  1XXA A;  1TWG A;  1O99 A;  1ZVU A;  1SHN A;  1O29 A;  3NKN A;  3DPC A;  3KD8 A;  5AJ9 A;  1Y6V A;  3WAV A;  4LQY A;  3H0G A;  1GE9 A;  3GTJ A;  1O28 A;  2B63 A;  5IOR A;  1Y1W A;  1EW9 A;  1KH7 A;  1O2A A;  3TWZ A;  4KAW X;  2VQR A;  1ED8 A;  1I3Q A;  3LAJ A;  2ZFZ A;  1FSU A;  5JVO A;  3NKQ A;  1ELZ A;  4GTX A;  3BUE A;  4GTB A;  1KHL A;  1BJT A;  2R7Z A;  1O2B A;  4KC6 A;  4LRA A;  3WAW A;  1ALJ A;  2XCO A;  3UO0 A;  1ED9 A;  4KAT A;  2CFA B;  2QZU A;  3MK2 A;  4KAY A;  4KB4 A;  3FHZ A;  1ZBS A;  2GSO A;  5INH A;  4CXK A;  3AQP A;  5C66 A;  3B5Q A;  1TWC A;  1EI6 A;  1SFO A;  3UNY A;  2W5Q A;  4LRE A;  2IUC A;  2R93 A;  3AQO A;  4NWX A;  1URB A;  2PHC B;  1DD5 A;  5L0K A;  3FOF A;  2W5R A;  5IJS A;  4KB2 A;  4FDI A;  4KAS A;  4ZG9 A;  3ED4 A;  2R92 A;  3L4K A;  5IOS A;  3GTM A;  4GTE A;  1KH9 A;  5K4P A;  3NKM A;  2JH3 A;  3OT9 A;  4ZG6 A;  1IS1 A;  1ALH A;  3BDF A;  3SZZ A;  1XXB A;  5JFE A;  3T01 A;  4LRF A;  1KQ4 A;  4BKW A;  3M8Z A;  1ELY A;  1URA A;  2JA7 A;  1HDH A;  1BGW A;  3UN3 A;  4P5B A;  4FM9 A;  4KJD A;  1TWA A;  3N0C A;  5EGE A;  1O98 A;  3SZY A;  4LR8 A;  2JA6 A;  3NVL A;  4CYR A;  4BLB A;  3NKR A;  5LRM A;  4N7T A;  5HRT A;  4C3I C;  4GTY A;  2G9Y A;  4G0V A;  3FKI A;  1AJA A;  3LPX A;  3M8W A;  3CQZ A;  3GTQ A;  1EK8 A;  5LQQ A;  2ANH A;  4MY4 A;  4KMD A;  1ZEB A;  1Y1V A;  1WCM A;  2CFA A;  4KM8 A;  5TJ3 A;  4UPH A;  4KMA A;  2XR9 A;  5DLV A;  1HJK A;  1KHK A;  1N2L A;  3MK1 A;  3CAG A;  3CMR A;  2GLQ A;  1EQJ A;  2JA5 A;  5LRN A;  2YU9 A;  5IJQ A;  3GTG A;  3Q3Q A;  1AJB A;  3UN2 A;  1I50 A;  4UPI A;  4MHX A;  2GA3 A;  2ZKT A;  4KDD A;  3QX3 A;  4LR9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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