4MEN | Genus

Total Genus 45

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	45
sequence length	127
structure length	127
Chain Sequence	SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transcription/transcription inhibitor
source organism	Homo sapiens
publication title	Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening. pubmed doi rcsb
molecule keywords	Bromodomain-containing protein 4
total genus	45
structure length	127
sequence length	127
ec nomenclature
pdb deposition date	2013-08-27

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00439	Bromodomain	Bromodomain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.920.10	Mainly Alpha	Up-down Bundle	Histone Acetyltransferase; Chain A	Bromodomain-like	4menA01

4PTBA 1ZS5A 3LQJA 4QR5A 3MXFA 5H1VA 5EGUA 5KTWA 4Z6IA 5CRZA 5DKCA 5ENFA 3LQHA 5I88A 3O37A 2DATA 4BJXA 4A9LA 1EQFA 2KTBB 5A7CA 2FSAA 4BW4A 5E9IA 5D24A 5FH8A 3G0LA 4UYFA 4XUAA 4LR6A 4E96A 5CU8A 5I1QA 5COIA 4QSSA 5ENEA 4XY9A 5IG6A 4LRGA 5G4RA 4IOQA 5HCLA 4QSQA 3O33A 5FH6A 3DAIA 3U5NA 5FDZA 3UVYA 5D3SA 4QC1A 5CUCA 4YYMA 2RNYA 4FLPA 4C66A 3AADA 4ZQLA 3SVGA 5DX4A 4CFKA 4ZC9A 2MJVB 4PKLA 5FB1A 5C85A 1WUMA 3UV5A 3HMFA 4F3IA 5BT4A 5ACYA 4MR5A 5FE3A 4J0SA 5I40A 3G0JA 5CRMA 5CUDA 4OGJA 5I29A 4TTEA 5H85A 5D0CA 5F63A 5E3DA 1WUGA 5TCMA 4LYIA 5BT3A 4NUDA 5CTLA 5CQ7A 5J0DA 4TU4A 5LJ0A 4BHWA 4Q0NA 5CQTA 4CUPA 4TQNA 3P1EA 4KCXA 5G4SA 4BW1A 2OSSA 4O7EA 4QSVA 4GPJA 5HM0A 3JVKA 5EICA 4YYIA 4QNSA 4NS5A 4QSXA 5CZGA 4HXSA 3JVJA 4KV4A 4NR8A 5DKDA 5KO4A 4CUQA 4UYEA 4IOOA 5EV9A 5F1HA 4Z1QA 3U5KA 5F2PA 5EPRA 3K2JA 4QEVA 3MQMA 5D26A 4Z93A 4MEOA 5D25A 4NUCA 3ZYUA 4CUUA 4PCIA 5JI8A 4XUBA 5DFCA 2R0SA 5A81A 4TU6A 5CQ8A 3DWYA 5FE7A 3O35A 5HRXA 4A9OA 4NR6A 4O78A 4UIUA 5L8TA 4YABA 3NXBA 5I7XA 2RO1A 5EK9A 4MR3A 4YAXA 3SVFA 2DVQA 5C8GA 4YBSA 2RS9B 4NR5A 4O7AA 5HQ5A 3S91A 1X0JA 5FBXA 5E73A 2RNXA 4BW2A 5FE5A 5F3AA 5EU1A 4N4FA 2E7OA 4MEPA 5C87A 5LKXA 4MEQA 4J0RA 5EWDA 5FE4A 5EM3A 5A5NA 4YBMA 4HBYA 5E9YA 4UYFB 4NRBA 4YBTA 4CLBA 2YELA 5D3TA 4O75A 4CURA 4A9HA 2R10A 5CQ6A 2D82A 5AMFA 4LZSA 1E6IA 5E9LA 5ENJA 5CUAA 5CUGA 2OO1A 4HXKA 4QUUA 4N4GA 4LDFA 5A5RA 5F62A 5DYXA 3LJWA 4NQMA 4YY6A 4IR6A 5CP5A 5D3LA 5DFBA 5ENCA 4A9MA 5LVRA 3U5MA 3Q2EA 5IGKA 3MB4A 4OUFA 4QC3A 5AD3A 5DW2A 4LZRA 4NR4A 4HXRA 3TLPA 4LYWA 4CUTA 5DYAA 4PCEA 4QR3A 5FFWA 5EISA 4NRCA 5C4QA 5F36A 5FE0A 5F60A 5E3GA 3IU6A 5F5ZA 5L96A 3U5JA 2I7KA 4QSRA 4O7FA 4QEWA 2YQDA 1N72A 5E0RA 4DONA 5HENA 4UIVA 5EVAA 3ONIA 4TT6A 2D9EA 3UW9A 2WP1A 4NYVA 4TZ2A 4OGIA 4A9EA 5FFYA 5DW1A 4A9NA 4HXMA 5TB6A 5ENBA 5ETBA 4N4IA 5HQ6A 2N9GA 4HBWA 5LKZA 4UYGA 5A82A 5F25A 3LQIA 4IR4A 4Q0OA 5HEMA 5LJ1A 3MULA 3P1CA 4YH4A 4O71A 2RFJA 4YYNA 5I86A 3FKMX 5A85A 3U5LA 4O70A 3UVWA 3P1FA 5HFQA 4YH3A 5II2A 5AD2A 4IORA 5E9VA 4TYLA 5FG6A 4RVRA 4HBVA 5CQ3A 5CQ5A 3QZTA 2I8NA 5AMEA 2F6JA 4UIXA 5E9KA 4PS5A 5EWCA 5FE2A 5IGLA 5JWMA 5KTXA 1JSPB 5DLZA 5A5PA 4QYDA 2DWWA 3QZSA 5EWHA 1F68A 5D7XA 4HBXA 4WHUA 4YADA 5E9MA 5EWWA 2E7NA 4TT2A 4NYWA 3O34A 4QSUA 4J3IA 4MR6A 3S92A 4QZSA 3AQAA 4QBMA 4QUTA 5CUEA 5F1LA 2NXBA 5A5OA 5IGMA 2G4AA 5D3JA 4Z1SA 4LC2A 5EQ1A 3U5OA 4O74A 2OUOA 5DKHA 5FG4A 5H1TA 5C89A 5IIDA 4O7CA 4YYKA 4CUSA 4XY8A 4YYDA 4UITA 4QEUA 5KTUA 3HMEA 5LVQA 4YYHA 5D3HA 2DVVA 5FH7A 4N4HA 5EPSA 5EPBA 5HRVA 4WIVA 5D3NA 2F6NA 5ENGA 5CPEA 4QSWA 4UIWA 1JM4B 5FE8A 5ETDA 5IBNA 5C7NA 5E74A 5K29A 5L99A 5A5SA 5HLSA 5D3RA 3HMHA 5DYUA 5IGNA 4XYAA 4UIYA 4YC9A 5FE1A 4ALGA 3RCWA 2RNWA 4UYDA 3GG3A 4TZ8A 4ZW1A 4NYXA 5DY7A 4O72A 4J1PA 5EP7A 5LJ2A 5A83A 3MB3A 2WP2A 2YEMA 4KV1A 5FFVA 4NXJA 4CFLA 4HXLA 5CFWA 5FE9A 4AKNA 3U5PA 4TT4A 4C67A 2R0YA 5CUBA 5L97A 4NUEA 4Y03A 5I89A 5FB0A 5II1A 2YYNA 5DBMA 5BT5A 3QZVA 4YYGA 5I83A 2H60A 4NR7A 4QY4A 5L8UA 3UV2A 4YY4A 4QSPA 4O76A 5EWVA 3UV4A 5DLXA 4BW3A 5CY9A 4HXNA 5ENHA 5I7YA 5ENIA 5HQ7A 4LYSA 3P1DA 4QR4A 3MUKA 2YDWA 4HXOA 5HJCA 4X2IA 2L5EA 4A9KA 2DVSA 3P5OA 5CGPA 4HXPA 3Q2FA 2DVRA 2LSPB 2RI7A 4MR4A 5KU3A 4WHWA 3JVMA 2YEKA 4YK0A 4TS8A 4QYLA 5A5QA 5L98A 5EA1A 4UYHA 4O77A 4YYJA 2L85A 5CS8A 3O36A 3LXJA 5D3PA 5HFRA 3UVXA 5FG5A 4IR3A 3JVLA 2GRCA 5DFDA 3UVDA 2DKWA 2E3KA 5CQ4A 4CL9A 2R0VA 4LZ2A 4A9IA 4ALHA 5F61A 4O7BA 4QB3A 3IU5A 4NQNA 5EI4A 5HRWA 5LKTA 4PY6A 2YW5A 4UIZA 3I3JA 3D7CA 4Z6HA 4QSTA 5KHMA 5LUUA 4NRAA 5FE6A 5CQAA 5H1UA 3SVHA 4YATA 5E7DA 2L84A 5I80A 4N3WA 4A9FA 5HELA 4MENA 4A9JA 5LKUA 4IR5A 5DYCA 4NR9A
chains in the Genus database with same CATH superfamily

4PTBA 1ZS5A 3LQJA 4QR5A 3MXFA 5H1VA 5EGUA 5KTWA 4Z6IA 5CRZA 5DKCA 5ENFA 3LQHA 5I88A 3O37A 2DATA 4BJXA 4A9LA 1EQFA 2KTBB 5A7CA 2FSAA 4BW4A 5E9IA 3D1BA 5D24A 5FH8A 3G0LA 4UYFA 4XUAA 4LR6A 4E96A 5CU8A 5I1QA 5COIA 4QSSA 5ENEA 4XY9A 5IG6A 4LRGA 5G4RA 4IOQA 3VKHA 5HCLA 4QSQA 4AKHA 3O33A 5FH6A 3DAIA 3U5NA 5FDZA 3UVYA 5D3SA 4QC1A 5CUCA 4YYMA 2RNYA 4FLPA 4C66A 3AADA 4ZQLA 3SVGA 5DX4A 4CFKA 4ZC9A 2MJVB 4PKLA 5FB1A 5C85A 1WUMA 3UV5A 3HMFA 4F3IA 5BT4A 5ACYA 4MR5A 5FE3A 4J0SA 5I40A 3G0JA 5CRMA 5CUDA 1ZKRA 4OGJA 5I29A 4TTEA 5H85A 5D0CA 5F63A 5E3DA 1WUGA 5TCMA 4LYIA 5BT3A 4NUDA 5CTLA 5CQ7A 5J0DA 4TU4A 5LJ0A 4BHWA 4Q0NA 5CQTA 4CUPA 4TQNA 3P1EA 4KCXA 5G4SA 4BW1A 2OSSA 4O7EA 4QSVA 4GPJA 5HM0A 3JVKA 5EICA 4YYIA 4QNSA 4NS5A 4QSXA 5CZGA 4HXSA 3JVJA 4KV4A 4NR8A 5DKDA 5KO4A 4CUQA 4UYEA 4IOOA 5EV9A 5F1HA 4Z1QA 3U5KA 5F2PA 5EPRA 3K2JA 4QEVA 3MQMA 5D26A 4Z93A 4MEOA 5D25A 4NUCA 3ZYUA 4CUUA 4PCIA 1PUOA 5JI8A 4XUBA 5DFCA 3ERRA 2R0SA 5A81A 4TU6A 5CQ8A 3DWYA 5FE7A 3O35A 5HRXA 4A9OA 4NR6A 4O78A 4UIUA 5L8TA 4YABA 3NXBA 5I7XA 2RO1A 5EK9A 4MR3A 4YAXA 3SVFA 2DVQA 5C8GA 4YBSA 2RS9B 4NR5A 4O7AA 5HQ5A 3S91A 1X0JA 5FBXA 5E73A 2RNXA 4BW2A 5FE5A 5F3AA 5EU1A 4N4FA 3D1DA 2E7OA 4MEPA 5C87A 5LKXA 4MEQA 4J0RA 5EWDA 5FE4A 5EM3A 5A5NA 4YBMA 4HBYA 5E9YA 4UYFB 4NRBA 4AKIA 4YBTA 4CLBA 2YELA 5D3TA 4O75A 4CURA 4A9HA 2R10A 5CQ6A 2D82A 5AMFA 4LZSA 1E6IA 5E9LA 5ENJA 5CUAA 5CUGA 2OO1A 4HXKA 4QUUA 4N4GA 4LDFA 5A5RA 5F62A 5DYXA 3LJWA 4NQMA 4YY6A 4IR6A 5CP5A 5D3LA 5DFBA 5ENCA 4A9MA 5LVRA 3U5MA 3Q2EA 5IGKA 3MB4A 4OUFA 4QC3A 5AD3A 5DW2A 4LZRA 4NR4A 4HXRA 3TLPA 4LYWA 4CUTA 5DYAA 4PCEA 4QR3A 5FFWA 5EISA 4NRCA 5C4QA 5F36A 5FE0A 5F60A 5E3GA 3IU6A 5F5ZA 5L96A 3U5JA 2I7KA 4QSRA 4O7FA 4QEWA 2YQDA 1N72A 5E0RA 4DONA 5HENA 4UIVA 5EVAA 3ONIA 4TT6A 2D9EA 3UW9A 2WP1A 4NYVA 4TZ2A 4OGIA 4A9EA 5FFYA 5DW1A 4A9NA 4HXMA 5TB6A 5ENBA 5ETBA 4N4IA 5HQ6A 2N9GA 4HBWA 5LKZA 4UYGA 5A82A 5F25A 3LQIA 4IR4A 4Q0OA 5HEMA 5LJ1A 3MULA 3P1CA 4YH4A 4O71A 2RFJA 4YYNA 5I86A 3FKMX 5A85A 3U5LA 4O70A 3UVWA 3P1FA 5HFQA 4YH3A 5II2A 5AD2A 4IORA 5E9VA 4TYLA 5FG6A 4RVRA 4HBVA 5CQ3A 5CQ5A 3QZTA 2I8NA 5AMEA 2F6JA 4UIXA 5E9KA 4PS5A 5EWCA 5FE2A 5IGLA 5JWMA 5KTXA 1JSPB 5DLZA 5A5PA 4QYDA 2DWWA 3QZSA 5EWHA 1F68A 5D7XA 4HBXA 4WHUA 4YADA 5E9MA 5EWWA 2E7NA 4TT2A 4NYWA 3O34A 4QSUA 4J3IA 4MR6A 3S92A 4QZSA 3AQAA 4QBMA 4QUTA 5CUEA 5F1LA 2NXBA 5A5OA 5IGMA 2G4AA 5D3JA 4Z1SA 4LC2A 5EQ1A 4AKGA 3U5OA 4O74A 2OUOA 5DKHA 5FG4A 5H1TA 5C89A 5IIDA 4O7CA 4YYKA 4CUSA 4XY8A 4YYDA 4UITA 4QEUA 5KTUA 3HMEA 5LVQA 4YYHA 5D3HA 2DVVA 5FH7A 4N4HA 5EPSA 5EPBA 5HRVA 4WIVA 5D3NA 2F6NA 5ENGA 5CPEA 4QSWA 4UIWA 1JM4B 5FE8A 5ETDA 5IBNA 5C7NA 5E74A 5K29A 5L99A 5A5SA 5HLSA 5D3RA 3HMHA 5DYUA 4AI6A 5IGNA 4XYAA 4UIYA 4YC9A 5FE1A 4ALGA 3RCWA 2RNWA 4UYDA 3GG3A 4TZ8A 4ZW1A 4NYXA 5DY7A 4O72A 4J1PA 5EP7A 5LJ2A 5A83A 3MB3A 2WP2A 2YEMA 4KV1A 5FFVA 4NXJA 4CFLA 4HXLA 5CFWA 5FE9A 4AKNA 3U5PA 4TT4A 4C67A 2R0YA 5CUBA 5L97A 4NUEA 4Y03A 5I89A 5FB0A 5II1A 2YYNA 5DBMA 5BT5A 3QZVA 4YYGA 2EJNA 5I83A 2H60A 4NR7A 4QY4A 5L8UA 3UV2A 4YY4A 4QSPA 4O76A 5EWVA 3UV4A 5DLXA 4BW3A 5CY9A 4HXNA 5ENHA 5I7YA 5ENIA 5HQ7A 4LYSA 3P1DA 4QR4A 3MUKA 2YDWA 4HXOA 5HJCA 4X2IA 2L5EA 4A9KA 2DVSA 3P5OA 5CGPA 4HXPA 3Q2FA 2DVRA 2LSPB 2RI7A 4MR4A 5KU3A 4WHWA 3JVMA 2YEKA 4YK0A 4TS8A 4QYLA 5A5QA 5L98A 5EA1A 4UYHA 4O77A 4YYJA 2L85A 5CS8A 3O36A 3LXJA 5D3PA 5HFRA 3UVXA 5FG5A 4IR3A 3JVLA 2GRCA 5DFDA 3UVDA 2DKWA 2E3KA 5CQ4A 4CL9A 2R0VA 4LZ2A 4A9IA 4ALHA 5F61A 4O7BA 4QB3A 3IU5A 4NQNA 3VKGA 5EI4A 5HRWA 5LKTA 4PY6A 2YW5A 4UIZA 3I3JA 3D7CA 4Z6HA 4QSTA 5KHMA 5LUUA 4NRAA 5FE6A 5CQAA 5H1UA 3SVHA 4YATA 5E7DA 2L84A 5I80A 4N3WA 4A9FA 5HELA 4MENA 4A9JA 5LKUA 4IR5A 5DYCA 4NR9A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4PTB A;  1ZS5 A;  3LQJ A;  4QR5 A;  3MXF A;  5H1V A;  5EGU A;  5KTW A;  4Z6I A;  5CRZ A;  5DKC A;  5ENF A;  3LQH A;  5I88 A;  3O37 A;  2DAT A;  4BJX A;  4A9L A;  1EQF A;  2KTB B;  5A7C A;  2FSA A;  4BW4 A;  5E9I A;  5D24 A;  5FH8 A;  3G0L A;  4UYF A;  4XUA A;  4LR6 A;  4E96 A;  5CU8 A;  5I1Q A;  5COI A;  4QSS A;  5ENE A;  4XY9 A;  5IG6 A;  4LRG A;  5G4R A;  4IOQ A;  5HCL A;  4QSQ A;  3O33 A;  5FH6 A;  3DAI A;  3U5N A;  5FDZ A;  3UVY A;  5D3S A;  4QC1 A;  5CUC A;  4YYM A;  2RNY A;  4FLP A;  4C66 A;  3AAD A;  4ZQL A;  3SVG A;  5DX4 A;  4CFK A;  4ZC9 A;  2MJV B;  4PKL A;  5FB1 A;  5C85 A;  1WUM A;  3UV5 A;  3HMF A;  4F3I A;  5BT4 A;  5ACY A;  4MR5 A;  5FE3 A;  4J0S A;  5I40 A;  3G0J A;  5CRM A;  5CUD A;  4OGJ A;  5I29 A;  4TTE A;  5H85 A;  5D0C A;  5F63 A;  5E3D A;  1WUG A;  5TCM A;  4LYI A;  5BT3 A;  4NUD A;  5CTL A;  5CQ7 A;  5J0D A;  4TU4 A;  5LJ0 A;  4BHW A;  4Q0N A;  5CQT A;  4CUP A;  4TQN A;  3P1E A;  4KCX A;  5G4S A;  4BW1 A;  2OSS A;  4O7E A;  4QSV A;  4GPJ A;  5HM0 A;  3JVK A;  5EIC A;  4YYI A;  4QNS A;  4NS5 A;  4QSX A;  5CZG A;  4HXS A;  3JVJ A;  4KV4 A;  4NR8 A;  5DKD A;  5KO4 A;  4CUQ A;  4UYE A;  4IOO A;  5EV9 A;  5F1H A;  4Z1Q A;  3U5K A;  5F2P A;  5EPR A;  3K2J A;  4QEV A;  3MQM A;  5D26 A;  4Z93 A;  4MEO A;  5D25 A;  4NUC A;  3ZYU A;  4CUU A;  4PCI A;  5JI8 A;  4XUB A;  5DFC A;  2R0S A;  5A81 A;  4TU6 A;  5CQ8 A;  3DWY A;  5FE7 A;  3O35 A;  5HRX A;  4A9O A;  4NR6 A;  4O78 A;  4UIU A;  5L8T A;  4YAB A;  3NXB A;  5I7X A;  2RO1 A;  5EK9 A;  4MR3 A;  4YAX A;  3SVF A;  2DVQ A;  5C8G A;  4YBS A;  2RS9 B;  4NR5 A;  4O7A A;  5HQ5 A;  3S91 A;  1X0J A;  5FBX A;  5E73 A;  2RNX A;  4BW2 A;  5FE5 A;  5F3A A;  5EU1 A;  4N4F A;  2E7O A;  4MEP A;  5C87 A;  5LKX A;  4MEQ A;  4J0R A;  5EWD A;  5FE4 A;  5EM3 A;  5A5N A;  4YBM A;  4HBY A;  5E9Y A;  4UYF B;  4NRB A;  4YBT A;  4CLB A;  2YEL A;  5D3T A;  4O75 A;  4CUR A;  4A9H A;  2R10 A;  5CQ6 A;  2D82 A;  5AMF A;  4LZS A;  1E6I A;  5E9L A;  5ENJ A;  5CUA A;  5CUG A;  2OO1 A;  4HXK A;  4QUU A;  4N4G A;  4LDF A;  5A5R A;  5F62 A;  5DYX A;  3LJW A;  4NQM A;  4YY6 A;  4IR6 A;  5CP5 A;  5D3L A;  5DFB A;  5ENC A;  4A9M A;  5LVR A;  3U5M A;  3Q2E A;  5IGK A;  3MB4 A;  4OUF A;  4QC3 A;  5AD3 A;  5DW2 A;  4LZR A;  4NR4 A;  4HXR A;  3TLP A;  4LYW A;  4CUT A;  5DYA A;  4PCE A;  4QR3 A;  5FFW A;  5EIS A;  4NRC A;  5C4Q A;  5F36 A;  5FE0 A;  5F60 A;  5E3G A;  3IU6 A;  5F5Z A;  5L96 A;  3U5J A;  2I7K A;  4QSR A;  4O7F A;  4QEW A;  2YQD A;  1N72 A;  5E0R A;  4DON A;  5HEN A;  4UIV A;  5EVA A;  3ONI A;  4TT6 A;  2D9E A;  3UW9 A;  2WP1 A;  4NYV A;  4TZ2 A;  4OGI A;  4A9E A;  5FFY A;  5DW1 A;  4A9N A;  4HXM A;  5TB6 A;  5ENB A;  5ETB A;  4N4I A;  5HQ6 A;  2N9G A;  4HBW A;  5LKZ A;  4UYG A;  5A82 A;  5F25 A;  3LQI A;  4IR4 A;  4Q0O A;  5HEM A;  5LJ1 A;  3MUL A;  3P1C A;  4YH4 A;  4O71 A;  2RFJ A;  4YYN A;  5I86 A;  3FKM X;  5A85 A;  3U5L A;  4O70 A;  3UVW A;  3P1F A;  5HFQ A;  4YH3 A;  5II2 A;  5AD2 A;  4IOR A;  5E9V A;  4TYL A;  5FG6 A;  4RVR A;  4HBV A;  5CQ3 A;  5CQ5 A;  3QZT A;  2I8N A;  5AME A;  2F6J A;  4UIX A;  5E9K A;  4PS5 A;  5EWC A;  5FE2 A;  5IGL A;  5JWM A;  5KTX A;  1JSP B;  5DLZ A;  5A5P A;  4QYD A;  2DWW A;  3QZS A;  5EWH A;  1F68 A;  5D7X A;  4HBX A;  4WHU A;  4YAD A;  5E9M A;  5EWW A;  2E7N A;  4TT2 A;  4NYW A;  3O34 A;  4QSU A;  4J3I A;  4MR6 A;  3S92 A;  4QZS A;  3AQA A;  4QBM A;  4QUT A;  5CUE A;  5F1L A;  2NXB A;  5A5O A;  5IGM A;  2G4A A;  5D3J A;  4Z1S A;  4LC2 A;  5EQ1 A;  3U5O A;  4O74 A;  2OUO A;  5DKH A;  5FG4 A;  5H1T A;  5C89 A;  5IID A;  4O7C A;  4YYK A;  4CUS A;  4XY8 A;  4YYD A;  4UIT A;  4QEU A;  5KTU A;  3HME A;  5LVQ A;  4YYH A;  5D3H A;  2DVV A;  5FH7 A;  4N4H A;  5EPS A;  5EPB A;  5HRV A;  4WIV A;  5D3N A;  2F6N A;  5ENG A;  5CPE A;  4QSW A;  4UIW A;  1JM4 B;  5FE8 A;  5ETD A;  5IBN A;  5C7N A;  5E74 A;  5K29 A;  5L99 A;  5A5S A;  5HLS A;  5D3R A;  3HMH A;  5DYU A;  5IGN A;  4XYA A;  4UIY A;  4YC9 A;  5FE1 A;  4ALG A;  3RCW A;  2RNW A;  4UYD A;  3GG3 A;  4TZ8 A;  4ZW1 A;  4NYX A;  5DY7 A;  4O72 A;  4J1P A;  5EP7 A;  5LJ2 A;  5A83 A;  3MB3 A;  2WP2 A;  2YEM A;  4KV1 A;  5FFV A;  4NXJ A;  4CFL A;  4HXL A;  5CFW A;  5FE9 A;  4AKN A;  3U5P A;  4TT4 A;  4C67 A;  2R0Y A;  5CUB A;  5L97 A;  4NUE A;  4Y03 A;  5I89 A;  5FB0 A;  5II1 A;  2YYN A;  5DBM A;  5BT5 A;  3QZV A;  4YYG A;  5I83 A;  2H60 A;  4NR7 A;  4QY4 A;  5L8U A;  3UV2 A;  4YY4 A;  4QSP A;  4O76 A;  5EWV A;  3UV4 A;  5DLX A;  4BW3 A;  5CY9 A;  4HXN A;  5ENH A;  5I7Y A;  5ENI A;  5HQ7 A;  4LYS A;  3P1D A;  4QR4 A;  3MUK A;  2YDW A;  4HXO A;  5HJC A;  4X2I A;  2L5E A;  4A9K A;  2DVS A;  3P5O A;  5CGP A;  4HXP A;  3Q2F A;  2DVR A;  2LSP B;  2RI7 A;  4MR4 A;  5KU3 A;  4WHW A;  3JVM A;  2YEK A;  4YK0 A;  4TS8 A;  4QYL A;  5A5Q A;  5L98 A;  5EA1 A;  4UYH A;  4O77 A;  4YYJ A;  2L85 A;  5CS8 A;  3O36 A;  3LXJ A;  5D3P A;  5HFR A;  3UVX A;  5FG5 A;  4IR3 A;  3JVL A;  2GRC A;  5DFD A;  3UVD A;  2DKW A;  2E3K A;  5CQ4 A;  4CL9 A;  2R0V A;  4LZ2 A;  4A9I A;  4ALH A;  5F61 A;  4O7B A;  4QB3 A;  3IU5 A;  4NQN A;  5EI4 A;  5HRW A;  5LKT A;  4PY6 A;  2YW5 A;  4UIZ A;  3I3J A;  3D7C A;  4Z6H A;  4QST A;  5KHM A;  5LUU A;  4NRA A;  5FE6 A;  5CQA A;  5H1U A;  3SVH A;  4YAT A;  5E7D A;  2L84 A;  5I80 A;  4N3W A;  4A9F A;  5HEL A;  4MEN A;  4A9J A;  5LKU A;  4IR5 A;  5DYC A;  4NR9 A; 
#chains in the Genus database with same CATH topology
 4PTB A;  1ZS5 A;  3LQJ A;  4QR5 A;  3MXF A;  5H1V A;  5EGU A;  5KTW A;  4Z6I A;  5CRZ A;  5DKC A;  5ENF A;  3LQH A;  5I88 A;  3O37 A;  2DAT A;  4BJX A;  4A9L A;  1EQF A;  2KTB B;  5A7C A;  2FSA A;  4BW4 A;  5E9I A;  3D1B A;  5D24 A;  5FH8 A;  3G0L A;  4UYF A;  4XUA A;  4LR6 A;  4E96 A;  5CU8 A;  5I1Q A;  5COI A;  4QSS A;  5ENE A;  4XY9 A;  5IG6 A;  4LRG A;  5G4R A;  4IOQ A;  3VKH A;  5HCL A;  4QSQ A;  4AKH A;  3O33 A;  5FH6 A;  3DAI A;  3U5N A;  5FDZ A;  3UVY A;  5D3S A;  4QC1 A;  5CUC A;  4YYM A;  2RNY A;  4FLP A;  4C66 A;  3AAD A;  4ZQL A;  3SVG A;  5DX4 A;  4CFK A;  4ZC9 A;  2MJV B;  4PKL A;  5FB1 A;  5C85 A;  1WUM A;  3UV5 A;  3HMF A;  4F3I A;  5BT4 A;  5ACY A;  4MR5 A;  5FE3 A;  4J0S A;  5I40 A;  3G0J A;  5CRM A;  5CUD A;  1ZKR A;  4OGJ A;  5I29 A;  4TTE A;  5H85 A;  5D0C A;  5F63 A;  5E3D A;  1WUG A;  5TCM A;  4LYI A;  5BT3 A;  4NUD A;  5CTL A;  5CQ7 A;  5J0D A;  4TU4 A;  5LJ0 A;  4BHW A;  4Q0N A;  5CQT A;  4CUP A;  4TQN A;  3P1E A;  4KCX A;  5G4S A;  4BW1 A;  2OSS A;  4O7E A;  4QSV A;  4GPJ A;  5HM0 A;  3JVK A;  5EIC A;  4YYI A;  4QNS A;  4NS5 A;  4QSX A;  5CZG A;  4HXS A;  3JVJ A;  4KV4 A;  4NR8 A;  5DKD A;  5KO4 A;  4CUQ A;  4UYE A;  4IOO A;  5EV9 A;  5F1H A;  4Z1Q A;  3U5K A;  5F2P A;  5EPR A;  3K2J A;  4QEV A;  3MQM A;  5D26 A;  4Z93 A;  4MEO A;  5D25 A;  4NUC A;  3ZYU A;  4CUU A;  4PCI A;  1PUO A;  5JI8 A;  4XUB A;  5DFC A;  3ERR A;  2R0S A;  5A81 A;  4TU6 A;  5CQ8 A;  3DWY A;  5FE7 A;  3O35 A;  5HRX A;  4A9O A;  4NR6 A;  4O78 A;  4UIU A;  5L8T A;  4YAB A;  3NXB A;  5I7X A;  2RO1 A;  5EK9 A;  4MR3 A;  4YAX A;  3SVF A;  2DVQ A;  5C8G A;  4YBS A;  2RS9 B;  4NR5 A;  4O7A A;  5HQ5 A;  3S91 A;  1X0J A;  5FBX A;  5E73 A;  2RNX A;  4BW2 A;  5FE5 A;  5F3A A;  5EU1 A;  4N4F A;  3D1D A;  2E7O A;  4MEP A;  5C87 A;  5LKX A;  4MEQ A;  4J0R A;  5EWD A;  5FE4 A;  5EM3 A;  5A5N A;  4YBM A;  4HBY A;  5E9Y A;  4UYF B;  4NRB A;  4AKI A;  4YBT A;  4CLB A;  2YEL A;  5D3T A;  4O75 A;  4CUR A;  4A9H A;  2R10 A;  5CQ6 A;  2D82 A;  5AMF A;  4LZS A;  1E6I A;  5E9L A;  5ENJ A;  5CUA A;  5CUG A;  2OO1 A;  4HXK A;  4QUU A;  4N4G A;  4LDF A;  5A5R A;  5F62 A;  5DYX A;  3LJW A;  4NQM A;  4YY6 A;  4IR6 A;  5CP5 A;  5D3L A;  5DFB A;  5ENC A;  4A9M A;  5LVR A;  3U5M A;  3Q2E A;  5IGK A;  3MB4 A;  4OUF A;  4QC3 A;  5AD3 A;  5DW2 A;  4LZR A;  4NR4 A;  4HXR A;  3TLP A;  4LYW A;  4CUT A;  5DYA A;  4PCE A;  4QR3 A;  5FFW A;  5EIS A;  4NRC A;  5C4Q A;  5F36 A;  5FE0 A;  5F60 A;  5E3G A;  3IU6 A;  5F5Z A;  5L96 A;  3U5J A;  2I7K A;  4QSR A;  4O7F A;  4QEW A;  2YQD A;  1N72 A;  5E0R A;  4DON A;  5HEN A;  4UIV A;  5EVA A;  3ONI A;  4TT6 A;  2D9E A;  3UW9 A;  2WP1 A;  4NYV A;  4TZ2 A;  4OGI A;  4A9E A;  5FFY A;  5DW1 A;  4A9N A;  4HXM A;  5TB6 A;  5ENB A;  5ETB A;  4N4I A;  5HQ6 A;  2N9G A;  4HBW A;  5LKZ A;  4UYG A;  5A82 A;  5F25 A;  3LQI A;  4IR4 A;  4Q0O A;  5HEM A;  5LJ1 A;  3MUL A;  3P1C A;  4YH4 A;  4O71 A;  2RFJ A;  4YYN A;  5I86 A;  3FKM X;  5A85 A;  3U5L A;  4O70 A;  3UVW A;  3P1F A;  5HFQ A;  4YH3 A;  5II2 A;  5AD2 A;  4IOR A;  5E9V A;  4TYL A;  5FG6 A;  4RVR A;  4HBV A;  5CQ3 A;  5CQ5 A;  3QZT A;  2I8N A;  5AME A;  2F6J A;  4UIX A;  5E9K A;  4PS5 A;  5EWC A;  5FE2 A;  5IGL A;  5JWM A;  5KTX A;  1JSP B;  5DLZ A;  5A5P A;  4QYD A;  2DWW A;  3QZS A;  5EWH A;  1F68 A;  5D7X A;  4HBX A;  4WHU A;  4YAD A;  5E9M A;  5EWW A;  2E7N A;  4TT2 A;  4NYW A;  3O34 A;  4QSU A;  4J3I A;  4MR6 A;  3S92 A;  4QZS A;  3AQA A;  4QBM A;  4QUT A;  5CUE A;  5F1L A;  2NXB A;  5A5O A;  5IGM A;  2G4A A;  5D3J A;  4Z1S A;  4LC2 A;  5EQ1 A;  4AKG A;  3U5O A;  4O74 A;  2OUO A;  5DKH A;  5FG4 A;  5H1T A;  5C89 A;  5IID A;  4O7C A;  4YYK A;  4CUS A;  4XY8 A;  4YYD A;  4UIT A;  4QEU A;  5KTU A;  3HME A;  5LVQ A;  4YYH A;  5D3H A;  2DVV A;  5FH7 A;  4N4H A;  5EPS A;  5EPB A;  5HRV A;  4WIV A;  5D3N A;  2F6N A;  5ENG A;  5CPE A;  4QSW A;  4UIW A;  1JM4 B;  5FE8 A;  5ETD A;  5IBN A;  5C7N A;  5E74 A;  5K29 A;  5L99 A;  5A5S A;  5HLS A;  5D3R A;  3HMH A;  5DYU A;  4AI6 A;  5IGN A;  4XYA A;  4UIY A;  4YC9 A;  5FE1 A;  4ALG A;  3RCW A;  2RNW A;  4UYD A;  3GG3 A;  4TZ8 A;  4ZW1 A;  4NYX A;  5DY7 A;  4O72 A;  4J1P A;  5EP7 A;  5LJ2 A;  5A83 A;  3MB3 A;  2WP2 A;  2YEM A;  4KV1 A;  5FFV A;  4NXJ A;  4CFL A;  4HXL A;  5CFW A;  5FE9 A;  4AKN A;  3U5P A;  4TT4 A;  4C67 A;  2R0Y A;  5CUB A;  5L97 A;  4NUE A;  4Y03 A;  5I89 A;  5FB0 A;  5II1 A;  2YYN A;  5DBM A;  5BT5 A;  3QZV A;  4YYG A;  2EJN A;  5I83 A;  2H60 A;  4NR7 A;  4QY4 A;  5L8U A;  3UV2 A;  4YY4 A;  4QSP A;  4O76 A;  5EWV A;  3UV4 A;  5DLX A;  4BW3 A;  5CY9 A;  4HXN A;  5ENH A;  5I7Y A;  5ENI A;  5HQ7 A;  4LYS A;  3P1D A;  4QR4 A;  3MUK A;  2YDW A;  4HXO A;  5HJC A;  4X2I A;  2L5E A;  4A9K A;  2DVS A;  3P5O A;  5CGP A;  4HXP A;  3Q2F A;  2DVR A;  2LSP B;  2RI7 A;  4MR4 A;  5KU3 A;  4WHW A;  3JVM A;  2YEK A;  4YK0 A;  4TS8 A;  4QYL A;  5A5Q A;  5L98 A;  5EA1 A;  4UYH A;  4O77 A;  4YYJ A;  2L85 A;  5CS8 A;  3O36 A;  3LXJ A;  5D3P A;  5HFR A;  3UVX A;  5FG5 A;  4IR3 A;  3JVL A;  2GRC A;  5DFD A;  3UVD A;  2DKW A;  2E3K A;  5CQ4 A;  4CL9 A;  2R0V A;  4LZ2 A;  4A9I A;  4ALH A;  5F61 A;  4O7B A;  4QB3 A;  3IU5 A;  4NQN A;  3VKG A;  5EI4 A;  5HRW A;  5LKT A;  4PY6 A;  2YW5 A;  4UIZ A;  3I3J A;  3D7C A;  4Z6H A;  4QST A;  5KHM A;  5LUU A;  4NRA A;  5FE6 A;  5CQA A;  5H1U A;  3SVH A;  4YAT A;  5E7D A;  2L84 A;  5I80 A;  4N3W A;  4A9F A;  5HEL A;  4MEN A;  4A9J A;  5LKU A;  4IR5 A;  5DYC A;  4NR9 A; 
#chains in the Genus database with same CATH homology
 4PTB A;  1ZS5 A;  3LQJ A;  4QR5 A;  3MXF A;  5H1V A;  5EGU A;  5KTW A;  4Z6I A;  5CRZ A;  5DKC A;  5ENF A;  3LQH A;  5I88 A;  3O37 A;  2DAT A;  4BJX A;  4A9L A;  1EQF A;  2KTB B;  5A7C A;  2FSA A;  4BW4 A;  5E9I A;  5D24 A;  5FH8 A;  3G0L A;  4UYF A;  4XUA A;  4LR6 A;  4E96 A;  5CU8 A;  5I1Q A;  5COI A;  4QSS A;  5ENE A;  4XY9 A;  5IG6 A;  4LRG A;  5G4R A;  4IOQ A;  5HCL A;  4QSQ A;  3O33 A;  5FH6 A;  3DAI A;  3U5N A;  5FDZ A;  3UVY A;  5D3S A;  4QC1 A;  5CUC A;  4YYM A;  2RNY A;  4FLP A;  4C66 A;  3AAD A;  4ZQL A;  3SVG A;  5DX4 A;  4CFK A;  4ZC9 A;  2MJV B;  4PKL A;  5FB1 A;  5C85 A;  1WUM A;  3UV5 A;  3HMF A;  4F3I A;  5BT4 A;  5ACY A;  4MR5 A;  5FE3 A;  4J0S A;  5I40 A;  3G0J A;  5CRM A;  5CUD A;  4OGJ A;  5I29 A;  4TTE A;  5H85 A;  5D0C A;  5F63 A;  5E3D A;  1WUG A;  5TCM A;  4LYI A;  5BT3 A;  4NUD A;  5CTL A;  5CQ7 A;  5J0D A;  4TU4 A;  5LJ0 A;  4BHW A;  4Q0N A;  5CQT A;  4CUP A;  4TQN A;  3P1E A;  4KCX A;  5G4S A;  4BW1 A;  2OSS A;  4O7E A;  4QSV A;  4GPJ A;  5HM0 A;  3JVK A;  5EIC A;  4YYI A;  4QNS A;  4NS5 A;  4QSX A;  5CZG A;  4HXS A;  3JVJ A;  4KV4 A;  4NR8 A;  5DKD A;  5KO4 A;  4CUQ A;  4UYE A;  4IOO A;  5EV9 A;  5F1H A;  4Z1Q A;  3U5K A;  5F2P A;  5EPR A;  3K2J A;  4QEV A;  3MQM A;  5D26 A;  4Z93 A;  4MEO A;  5D25 A;  4NUC A;  3ZYU A;  4CUU A;  4PCI A;  5JI8 A;  4XUB A;  5DFC A;  2R0S A;  5A81 A;  4TU6 A;  5CQ8 A;  3DWY A;  5FE7 A;  3O35 A;  5HRX A;  4A9O A;  4NR6 A;  4O78 A;  4UIU A;  5L8T A;  4YAB A;  3NXB A;  5I7X A;  2RO1 A;  5EK9 A;  4MR3 A;  4YAX A;  3SVF A;  2DVQ A;  5C8G A;  4YBS A;  2RS9 B;  4NR5 A;  4O7A A;  5HQ5 A;  3S91 A;  1X0J A;  5FBX A;  5E73 A;  2RNX A;  4BW2 A;  5FE5 A;  5F3A A;  5EU1 A;  4N4F A;  2E7O A;  4MEP A;  5C87 A;  5LKX A;  4MEQ A;  4J0R A;  5EWD A;  5FE4 A;  5EM3 A;  5A5N A;  4YBM A;  4HBY A;  5E9Y A;  4UYF B;  4NRB A;  4YBT A;  4CLB A;  2YEL A;  5D3T A;  4O75 A;  4CUR A;  4A9H A;  2R10 A;  5CQ6 A;  2D82 A;  5AMF A;  4LZS A;  1E6I A;  5E9L A;  5ENJ A;  5CUA A;  5CUG A;  2OO1 A;  4HXK A;  4QUU A;  4N4G A;  4LDF A;  5A5R A;  5F62 A;  5DYX A;  3LJW A;  4NQM A;  4YY6 A;  4IR6 A;  5CP5 A;  5D3L A;  5DFB A;  5ENC A;  4A9M A;  5LVR A;  3U5M A;  3Q2E A;  5IGK A;  3MB4 A;  4OUF A;  4QC3 A;  5AD3 A;  5DW2 A;  4LZR A;  4NR4 A;  4HXR A;  3TLP A;  4LYW A;  4CUT A;  5DYA A;  4PCE A;  4QR3 A;  5FFW A;  5EIS A;  4NRC A;  5C4Q A;  5F36 A;  5FE0 A;  5F60 A;  5E3G A;  3IU6 A;  5F5Z A;  5L96 A;  3U5J A;  2I7K A;  4QSR A;  4O7F A;  4QEW A;  2YQD A;  1N72 A;  5E0R A;  4DON A;  5HEN A;  4UIV A;  5EVA A;  3ONI A;  4TT6 A;  2D9E A;  3UW9 A;  2WP1 A;  4NYV A;  4TZ2 A;  4OGI A;  4A9E A;  5FFY A;  5DW1 A;  4A9N A;  4HXM A;  5TB6 A;  5ENB A;  5ETB A;  4N4I A;  5HQ6 A;  2N9G A;  4HBW A;  5LKZ A;  4UYG A;  5A82 A;  5F25 A;  3LQI A;  4IR4 A;  4Q0O A;  5HEM A;  5LJ1 A;  3MUL A;  3P1C A;  4YH4 A;  4O71 A;  2RFJ A;  4YYN A;  5I86 A;  3FKM X;  5A85 A;  3U5L A;  4O70 A;  3UVW A;  3P1F A;  5HFQ A;  4YH3 A;  5II2 A;  5AD2 A;  4IOR A;  5E9V A;  4TYL A;  5FG6 A;  4RVR A;  4HBV A;  5CQ3 A;  5CQ5 A;  3QZT A;  2I8N A;  5AME A;  2F6J A;  4UIX A;  5E9K A;  4PS5 A;  5EWC A;  5FE2 A;  5IGL A;  5JWM A;  5KTX A;  1JSP B;  5DLZ A;  5A5P A;  4QYD A;  2DWW A;  3QZS A;  5EWH A;  1F68 A;  5D7X A;  4HBX A;  4WHU A;  4YAD A;  5E9M A;  5EWW A;  2E7N A;  4TT2 A;  4NYW A;  3O34 A;  4QSU A;  4J3I A;  4MR6 A;  3S92 A;  4QZS A;  3AQA A;  4QBM A;  4QUT A;  5CUE A;  5F1L A;  2NXB A;  5A5O A;  5IGM A;  2G4A A;  5D3J A;  4Z1S A;  4LC2 A;  5EQ1 A;  3U5O A;  4O74 A;  2OUO A;  5DKH A;  5FG4 A;  5H1T A;  5C89 A;  5IID A;  4O7C A;  4YYK A;  4CUS A;  4XY8 A;  4YYD A;  4UIT A;  4QEU A;  5KTU A;  3HME A;  5LVQ A;  4YYH A;  5D3H A;  2DVV A;  5FH7 A;  4N4H A;  5EPS A;  5EPB A;  5HRV A;  4WIV A;  5D3N A;  2F6N A;  5ENG A;  5CPE A;  4QSW A;  4UIW A;  1JM4 B;  5FE8 A;  5ETD A;  5IBN A;  5C7N A;  5E74 A;  5K29 A;  5L99 A;  5A5S A;  5HLS A;  5D3R A;  3HMH A;  5DYU A;  5IGN A;  4XYA A;  4UIY A;  4YC9 A;  5FE1 A;  4ALG A;  3RCW A;  2RNW A;  4UYD A;  3GG3 A;  4TZ8 A;  4ZW1 A;  4NYX A;  5DY7 A;  4O72 A;  4J1P A;  5EP7 A;  5LJ2 A;  5A83 A;  3MB3 A;  2WP2 A;  2YEM A;  4KV1 A;  5FFV A;  4NXJ A;  4CFL A;  4HXL A;  5CFW A;  5FE9 A;  4AKN A;  3U5P A;  4TT4 A;  4C67 A;  2R0Y A;  5CUB A;  5L97 A;  4NUE A;  4Y03 A;  5I89 A;  5FB0 A;  5II1 A;  2YYN A;  5DBM A;  5BT5 A;  3QZV A;  4YYG A;  5I83 A;  2H60 A;  4NR7 A;  4QY4 A;  5L8U A;  3UV2 A;  4YY4 A;  4QSP A;  4O76 A;  5EWV A;  3UV4 A;  5DLX A;  4BW3 A;  5CY9 A;  4HXN A;  5ENH A;  5I7Y A;  5ENI A;  5HQ7 A;  4LYS A;  3P1D A;  4QR4 A;  3MUK A;  2YDW A;  4HXO A;  5HJC A;  4X2I A;  2L5E A;  4A9K A;  2DVS A;  3P5O A;  5CGP A;  4HXP A;  3Q2F A;  2DVR A;  2LSP B;  2RI7 A;  4MR4 A;  5KU3 A;  4WHW A;  3JVM A;  2YEK A;  4YK0 A;  4TS8 A;  4QYL A;  5A5Q A;  5L98 A;  5EA1 A;  4UYH A;  4O77 A;  4YYJ A;  2L85 A;  5CS8 A;  3O36 A;  3LXJ A;  5D3P A;  5HFR A;  3UVX A;  5FG5 A;  4IR3 A;  3JVL A;  2GRC A;  5DFD A;  3UVD A;  2DKW A;  2E3K A;  5CQ4 A;  4CL9 A;  2R0V A;  4LZ2 A;  4A9I A;  4ALH A;  5F61 A;  4O7B A;  4QB3 A;  3IU5 A;  4NQN A;  5EI4 A;  5HRW A;  5LKT A;  4PY6 A;  2YW5 A;  4UIZ A;  3I3J A;  3D7C A;  4Z6H A;  4QST A;  5KHM A;  5LUU A;  4NRA A;  5FE6 A;  5CQA A;  5H1U A;  3SVH A;  4YAT A;  5E7D A;  2L84 A;  5I80 A;  4N3W A;  4A9F A;  5HEL A;  4MEN A;  4A9J A;  5LKU A;  4IR5 A;  5DYC A;  4NR9 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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4MENA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations