The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
28
|
sequence length |
179
|
structure length |
179
|
Chain Sequence |
GSHMEMAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQCASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETGSGC
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA-mediated activation.
pubmed doi rcsb |
| molecule tags |
Transferase
|
| source organism |
Homo sapiens
|
| molecule keywords |
PROTEIN KINASE PKR
|
| total genus |
28
|
| structure length |
179
|
| sequence length |
179
|
| ec nomenclature |
ec
2.7.10.2: Non-specific protein-tyrosine kinase. |
| pdb deposition date | 1999-07-08 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00035 | dsrm | Double-stranded RNA binding motif |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | Double Stranded RNA Binding Domain | Double Stranded RNA Binding Domain | ||
| Alpha Beta | 2-Layer Sandwich | Double Stranded RNA Binding Domain | Double Stranded RNA Binding Domain |
#chains in the Genus database with same CATH superfamily 4YY3 E; 4X66 E; 1RQ0 A; 4DV2 E; 3J7Y p; 1IBM E; 4JI6 E; 1T4L B; 1HNX E; 4X64 E; 5IWA E; 1O0W A; 4DV6 E; 2L3C A; 5LMN E; 2LBS B; 5LMU E; 2L2N A; 2F4V E; 1T4N A; 1FKA E; 2LTS A; 5CFF E; 1J5E E; 4OX9 E; 2LUQ A; 1J26 A; 3VYY A; 2RSM A; 3ADG A; 4JI1 E; 2NUG A; 1RC7 A; 1IBL E; 2UUB E; 2UXC E; 3C4T A; 4DR2 E; 4B3M E; 1XNR E; 2UU9 E; 1HNW E; 2NA2 A; 4JI0 E; 4GKJ E; 2DMY A; 3OTO E; 1IBK E; 1HR0 E; 4B3T E; 4M2Z A; 2LUP B; 2L2K B; 1XMQ E; 2NUF A; 2L3J A; 2LTR A; 2HHH E; 4JI2 E; 4WFT A; 2DB2 A; 4DR1 E; 4LFC E; 4DR6 E; 4DUZ E; 4K0K E; 2E5L E; 1T4O A; 1UHZ A; 1HNZ E; 3HTX A; 2L2M A; 2N3H A; 4DR4 E; 4JI7 E; 4DR3 E; 1QU6 A; 2B3T B; 4DV7 E; 2UXB E; 2MDR A; 1WHQ A; 4DV5 E; 4YHH E; 4LF5 E; 3ADJ A; 4LF7 E; 1DI2 A; 4DV1 E; 5BR8 E; 2EZ6 A; 2LRS A; 2VQF E; 4AQY E; 2B7V A; 1YYO A; 1N33 E; 4M30 A; 2UUA E; 4DR7 E; 4JV5 E; 1XMO E; 2LJH A; 4LF9 E; 1PKP A; 4X62 E; 1N36 E; 4JI4 E; 2DIX A; 1X47 A; 2B7T A; 3VYX A; 4GKK E; 1WHN A; 1X49 A; 3ADI A; 1ZBT A; 4DKK A; 2VQE E; 2RS6 A; 2NUE A; 1I94 E; 1N32 E; 4JYA E; 4JI5 E; 2KHX A; 1XNQ E; 4LFA E; 1YYK A; 1GQE A; 3LLH A; 4KHP E; 4WYQ B; 2L33 A; 2JY9 A; 1UIL A; 4JI8 E; 4B3R E; 1STU A; 4DUY E; 1X48 A; 1EKZ A; 2RTX A; 2JVA A; 2N3G A; 3ADL A; 4LF8 E; 4DR5 E; 4LF6 E; 1FJG E; 4NXM E; 4DV0 E; 2YT4 A; 1YYW A; 4DV3 E; 2UUC E; 2ZM6 E; 4X8W A; 1YZ9 A; 3P1X A; 3C4B A; 3T1H E; 2CPN A; 4OOG C; 2RS7 A; 2IHR 1; 4NXN E; 4JI3 E; 4LFB E; 4B3S E; 3T1Y E; 4DV4 E; 4X65 E; 1N34 E; 2UXD E; 4LF4 E; #chains in the Genus database with same CATH topology 3LML A; 3TQM A; 4YY3 E; 4X66 E; 4IJD A; 2LMZ A; 3J7Y p; 1N3G A; 1IBM E; 1IQS A; 2EM8 A; 1EH6 A; 1PDA A; 1JK2 A; 5F3W A; 4F9B B; 3EPH A; 2EPO A; 2Q8U A; 2YU5 A; 4N4R B; 4BMJ A; 2DLK A; 2LTS A; 5CFF E; 5A6A A; 1YUI A; 1PJQ A; 2EMA A; 3KZY A; 2HJJ A; 2EQ0 A; 3C4T A; 4M9V C; 1PJT A; 1A1G A; 4JI0 E; 5A6K A; 3J80 C; 2LT7 A; 3RMP A; 4BHB A; 1IBK E; 4M2Z A; 2ODR D; 4DMI A; 2I9I A; 3MHH C; 1GZ6 A; 2YU8 A; 4WFT A; 1X5W A; 2L2M A; 4L5N C; 1UBD C; 1EH7 A; 2B3T B; 2ODR C; 4IS1 C; 2UXB E; 1WHQ A; 4YHH E; 4NHR A; 3HPZ A; 1WRJ A; 2YTN A; 4R2D A; 4WSP A; 2EZ6 A; 1ZAA C; 2DRP A; 2EN8 A; 2RPC A; 4AQY E; 1YYO A; 3AUZ A; 2ELY A; 4J8Z A; 2YPN A; 4R2E A; 2EOS A; 2EM9 A; 4X9J A; 2LE2 A; 4JI4 E; 2YZT A; 2EN1 A; 1UN6 B; 2G7H A; 1A1H A; 4GKK E; 1WHN A; 4RHB B; 1QNT A; 2YTG A; 4DKK A; 4R2C A; 2VQE E; 2EM3 A; 2RS6 A; 1G2F C; 2NUE A; 1I94 E; 2H36 X; 2DGC A; 4JI5 E; 2LJU A; 3EQ1 A; 2FGG A; 1EH8 A; 5AC4 A; 2CT1 A; 1TF3 A; 1ZU1 A; 1BB8 A; 1X48 A; 2M9A A; 4BS9 A; 5KL3 A; 2GHF A; 4HEI A; 2YSO A; 4LF8 E; 2JR1 A; 2GLI A; 3ZOQ B; 4LF6 E; 2V8Q B; 4DV0 E; 4ZYD A; 2EMF A; 2UUC E; 1NEI A; 2EPP A; 1YUJ A; 4ZYG A; 2EMK A; 2EOJ A; 3IWB A; 2WBU A; 2YTE A; 3KZZ A; 3P1X A; 1YZ9 A; 4Q28 A; 3C4B A; 3T1H E; 2VE7 C; 4OOG C; 4TUG A; 4HTG A; 3T1Y E; 3EPK A; 2MKN A; 2EMX A; 5IV8 B; 2LO3 A; 4LU9 A; 2EOX A; 2EN7 A; 1T4L B; 1HNX E; 4P7D A; 4X64 E; 1A1J A; 1YSA C; 2ENC A; 1O0W A; 4DV6 E; 2I13 A; 3J7A G; 5LMN E; 2EN3 A; 4NZV A; 3MSW A; 1RMD A; 2YTP A; 4OX9 E; 2RSM A; 2VRD A; 2MC5 A; 2EPK X; 4F9C B; 2NUG A; 1IBL E; 2EOY A; 2UXC E; 2MC6 A; 2D9H A; 2FTX B; 4B3M E; 3HQ1 A; 2RQL A; 2UU9 E; 1KYQ A; 3H09 A; 2EPR A; 3J81 C; 2EJ4 A; 4GKJ E; 2DMY A; 1HR0 E; 1L4S A; 2EPC A; 3QG5 C; 4B3T E; 2EPL X; 1XMQ E; 4O4K A; 2L3J A; 2LTR A; 2HHH E; 2A25 A; 2EOM A; 4MLV A; 4R2P A; 2FV4 B; 1T39 A; 1WXR A; 2EMH A; 4DUZ E; 4K0K E; 4GEQ B; 1T4O A; 1HNZ E; 4DR4 E; 3IWC A; 1DGC A; 2E1M A; 1QU6 A; 3EPL A; 4DV7 E; 4WXD A; 4DV5 E; 4LF5 E; 1DI2 A; 2EMI A; 2EM6 A; 4F54 A; 2VF1 A; 5T6J A; 2F8B A; 4KWY A; 1N33 E; 4M30 A; 4DR7 E; 2YTI A; 1PKP A; 1N36 E; 5A6B D; 2DIX A; 4WPY A; 1X47 A; 2HC5 A; 2EOI A; 3IWD A; 2GPI A; 3ADI A; 2PRT A; 3AV0 A; 2EM7 A; 2KHX A; 3VK6 A; 2EN2 A; 2LCE A; 1DQ3 A; 3LLH A; 4R2R A; 4KHP E; 4WYQ B; 2L33 A; 2JY9 A; 2M7Q A; 2EPZ A; 2EMY A; 2EQ3 A; 1EKZ A; 2RTX A; 3JU0 A; 3K6Q A; 3BGH A; 4KZS A; 1JK1 A; 1FJG E; 2JPA A; 3BBG A; 2WBS A; 1T38 A; 2EPX A; 3JTZ A; 2ZM6 E; 4P78 A; 1ZBQ A; 2KOU A; 2EOQ A; 2EOE A; 1BBG A; 2RS7 A; 2B9D A; 2EPM X; 1IQO A; 4JI3 E; 4B3S E; 4X65 E; 2R76 A; 2UXD E; 2YTQ A; 4LF4 E; 4ZYE A; 1RQ0 A; 2EWL A; 3VHT B; 4JI6 E; 2EQ1 A; 5FLX C; 2DLQ A; 2EE8 A; 1Z1B A; 2R1F A; 4O5G A; 2YTJ A; 2L3C A; 2LBS B; 2L2N A; 5AE3 A; 1A1I A; 4TUI A; 5LL6 R; 1FKA E; 4WSG A; 1BBO A; 1J26 A; 3VYY A; 3ADG A; 4BC7 A; 5IT9 C; 1P47 A; 4I8O A; 4JI1 E; 1RC7 A; 3JAM C; 1XNR E; 3BID A; 1SR9 A; 2E72 A; 2V85 A; 2NA2 A; 2L2K B; 2ENH A; 2EMW A; 4R2Q A; 2NUF A; 2JXP A; 2EP3 A; 1MGT A; 4F6M A; 4FK5 C; 4ZYH A; 2YWQ A; 1B69 A; 1WJP A; 3EPJ A; 2V88 A; 2JOX A; 2E5L E; 1IMU A; 4JI7 E; 2J7J A; 4O24 A; 2MDR A; 4R03 A; 4RH8 A; 1A1L A; 3FIG A; 2N8X A; 4LF7 E; 2JYA A; 2MDG A; 2LV2 A; 2ELZ A; 1SFE A; 5A6J A; 2VQF E; 2B7V A; 4F9A B; 5AE1 A; 2DMI A; 1XMO E; 4LF9 E; 5KL6 A; 2M4I A; 2EOR A; 3C6K A; 2JP9 A; 3VYX A; 3THN A; 4MLQ A; 1ZBT A; 2L8T A; 5IXM B; 1N32 E; 2LVH A; 2BB8 A; 1XNQ E; 4LFA E; 1YYK A; 1GQE A; 1YFH A; 1X6E A; 1GTK A; 1UIL A; 3F6G A; 4B3R E; 1STU A; 2JVA A; 3ADL A; 1X3C A; 1X6F A; 2YT4 A; 5KL4 A; 5DNY A; 2EM0 A; 2EN4 A; 2EPA A; 2NAB A; 4BHC A; 2YTD A; 2CPN A; 5TSE A; 3L00 A; 3ECR A; 5AAS A; 2EMZ A; 2WBT A; 2YSP A; 4DV4 E; 1N34 E; 2EM5 A; 5LLQ A; 5AC5 A; 4GZN C; 4F2J C; 2YRK A; 4DV2 E; 1AH5 A; 5A69 A; 3F6H A; 2EOO A; 3DJW A; 2JOB A; 3DF6 A; 2V86 A; 2HGH A; 1ZR9 A; 5IWA E; 3HPS A; 2DSY A; 3HXL A; 2EL5 A; 2EOH A; 2EL6 A; 2EL4 A; 5LMU E; 2YRH A; 2F4V E; 1T4N A; 2EPU A; 1NCS A; 1J5E E; 1X6H A; 2LUQ A; 1YPN A; 2V83 A; 4BBY A; 3BF2 A; 3KWR A; 2UUB E; 4DR2 E; 1HNW E; 1PJS A; 3OTO E; 3MHS C; 2LUP B; 2V89 A; 4F6N A; 5ADZ A; 4JI2 E; 2EM4 A; 4L8N A; 2CSH A; 2L92 A; 2EPN A; 2DB2 A; 4DR1 E; 4LFC E; 4DR6 E; 5A2Q C; 1UHZ A; 2EMG A; 5AE2 A; 3HTX A; 2N3H A; 1KJK A; 4R2S A; 4DR3 E; 3ADJ A; 2L6M A; 3UK3 C; 4DV1 E; 5BR8 E; 1F2I G; 2YRM A; 2LRS A; 2K4V A; 2WZO A; 2YTO A; 2EMB A; 2UUA E; 4R2A A; 4JV5 E; 2ADR A; 2LJH A; 2ENA A; 1LLM C; 4X62 E; 4M0V A; 4O43 A; 2B7T A; 2K7I A; 5KL5 A; 2EMC A; 5KL7 A; 4LTY A; 1X49 A; 1G2D C; 1A1F A; 1A1K A; 3M99 B; 2EOF A; 4JYA E; 4BC9 A; 5KL2 A; 4WXC A; 4WX9 A; 2KON A; 2CTD A; 4R8O A; 5A6B A; 4BCA A; 2MKD A; 4JI8 E; 1TF6 A; 2JWO A; 4DUY E; 2WCC 3; 1MEY C; 2N3G A; 2RSI A; 4Q35 B; 4DR5 E; 3THO B; 3OML A; 4NXM E; 2YTF A; 1YYW A; 4DV3 E; 2V87 A; 1AAY A; 4X8W A; 1TN9 A; 2BBG A; 2EOZ A; 2EM2 A; 2EN6 A; 2M1S A; 2IHR 1; 4NXN E; 3C6M A; 4LFB E; 2EML A; #chains in the Genus database with same CATH homology 3LML A; 4YY3 E; 4X66 E; 1RQ0 A; 4DV2 E; 2LMZ A; 3J7Y p; 1IBM E; 4LU9 A; 3F6H A; 3DJW A; 2JOB A; 2EWL A; 2V86 A; 3DF6 A; 1T4L B; 1HNX E; 4JI6 E; 5FLX C; 4P7D A; 4X64 E; 5IWA E; 3HPS A; 2DSY A; 5F3W A; 1O0W A; 4F9B B; 4DV6 E; 3J7A G; 3HXL A; 2L3C A; 5LMN E; 2LBS B; 5LMU E; 2L2N A; 4BMJ A; 5AE3 A; 1T4N A; 4TUI A; 2F4V E; 3MSW A; 2LTS A; 5LL6 R; 5CFF E; 1FKA E; 1J5E E; 4OX9 E; 2LUQ A; 2V83 A; 1J26 A; 4BBY A; 2RSM A; 3ADG A; 4BC7 A; 2MC5 A; 3VYY A; 4I8O A; 3KWR A; 4F9C B; 5IT9 C; 1RC7 A; 1IBL E; 2UUB E; 4JI1 E; 2MC6 A; 3C4T A; 3JAM C; 2FTX B; 4DR2 E; 4B3M E; 3HQ1 A; 1XNR E; 1SR9 A; 2UU9 E; 2V85 A; 3H09 A; 3J81 C; 1HNW E; 2NA2 A; 4JI0 E; 4GKJ E; 2DMY A; 3J80 C; 3OTO E; 3RMP A; 1IBK E; 1HR0 E; 4B3T E; 4M2Z A; 2LUP B; 2L2K B; 2ODR D; 2V89 A; 4DMI A; 1XMQ E; 2NUF A; 2L3J A; 2LTR A; 2HHH E; 5ADZ A; 4JI2 E; 2FV4 B; 4L8N A; 2L92 A; 1GZ6 A; 4WFT A; 2DB2 A; 4DR1 E; 1WXR A; 4LFC E; 4DR6 E; 2V88 A; 2JOX A; 4DUZ E; 4K0K E; 4GEQ B; 2E5L E; 1T4O A; 1UHZ A; 5AE2 A; 5A2Q C; 1HNZ E; 2L2M A; 2N3H A; 3HTX A; 3IWC A; 4DR4 E; 4JI7 E; 2E1M A; 1QU6 A; 4L5N C; 4DR3 E; 2B3T B; 4DV7 E; 2ODR C; 2UXB E; 2MDR A; 1WHQ A; 4R03 A; 4DV5 E; 4YHH E; 4LF5 E; 3ADJ A; 2L6M A; 3FIG A; 4LF7 E; 3HPZ A; 1DI2 A; 4DV1 E; 5BR8 E; 4F54 A; 2VF1 A; 4WSP A; 2EZ6 A; 2LRS A; 2K4V A; 2WZO A; 5T6J A; 2VQF E; 2F8B A; 4AQY E; 2B7V A; 1YYO A; 1N33 E; 3AUZ A; 4M30 A; 4F9A B; 2UUA E; 4DR7 E; 4JV5 E; 5AE1 A; 4J8Z A; 1XMO E; 2LJH A; 4LF9 E; 2M4I A; 2UXC E; 1PKP A; 2NUG A; 2LE2 A; 4X62 E; 4M0V A; 1N36 E; 2YZT A; 4JI4 E; 2DIX A; 4WPY A; 1X47 A; 2B7T A; 3VYX A; 2G7H A; 3IWD A; 4GKK E; 1WHN A; 4LTY A; 1X49 A; 3ADI A; 1ZBT A; 4DKK A; 2L8T A; 3AV0 A; 2VQE E; 2RS6 A; 2NUE A; 1I94 E; 1N32 E; 4JYA E; 2H36 X; 4BC9 A; 4JI5 E; 2KHX A; 2KON A; 2FGG A; 1XNQ E; 3VK6 A; 4LFA E; 1YYK A; 1GQE A; 1DQ3 A; 3LLH A; 4KHP E; 4R8O A; 4WYQ B; 2L33 A; 2JY9 A; 1UIL A; 4JI8 E; 4BCA A; 2M7Q A; 3F6G A; 4B3R E; 1STU A; 2JWO A; 4DUY E; 1X48 A; 4BS9 A; 2RTX A; 1EKZ A; 2JVA A; 3JU0 A; 2N3G A; 3K6Q A; 4LF8 E; 4DR5 E; 4KZS A; 3ADL A; 2JR1 A; 4LF6 E; 3ZOQ B; 3OML A; 2V8Q B; 4NXM E; 4DV0 E; 2YT4 A; 1FJG E; 1YYW A; 4DV3 E; 2UUC E; 2V87 A; 5DNY A; 3JTZ A; 2ZM6 E; 4X8W A; 3IWB A; 4P78 A; 3P1X A; 1YZ9 A; 4Q28 A; 1ZBQ A; 3C4B A; 3T1H E; 2KOU A; 2CPN A; 2VE7 C; 4OOG C; 2M1S A; 2IHR 1; 2RS7 A; 4TUG A; 4NXN E; 2B9D A; 5AAS A; 4JI3 E; 4LFB E; 4B3S E; 3T1Y E; 4DV4 E; 4X65 E; 1N34 E; 2UXD E; 4LF4 E;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
