The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
26
|
sequence length |
126
|
structure length |
119
|
Chain Sequence |
KVLTIKSCNIHSGIGIRPHAQIELEYQGKIHKEISEGDGGYDAFMNALTKITNRLGISIPKLIDYEVRIPPGGKTDALVETRITWNDQTFKTMGVHPDQTVAAVHATEKMLNQILQPWQ
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans
pubmed doi rcsb |
| molecule keywords |
Alpha-isopropylmalate synthase
|
| molecule tags |
Transferase
|
| source organism |
Leptospira interrogans
|
| total genus |
26
|
| structure length |
119
|
| sequence length |
126
|
| chains with identical sequence |
B
|
| ec nomenclature |
ec
2.3.1.182: (R)-citramalate synthase. |
| pdb deposition date | 2008-11-06 |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | Double Stranded RNA Binding Domain | Double Stranded RNA Binding Domain | ||
| Alpha Beta | 2-Layer Sandwich | Double Stranded RNA Binding Domain | Double Stranded RNA Binding Domain |
#chains in the Genus database with same CATH superfamily 3F6H A; 3F6G A; #chains in the Genus database with same CATH topology 4AQY E; 3EPJ A; 2EM3 A; 2MC5 A; 2YTD A; 3L00 A; 1X5W A; 4R2Q A; 4DR6 E; 1X6H A; 1O0W A; 3THO B; 4B3S E; 4NXM E; 4DV0 E; 2V87 A; 1KJK A; 3JU0 A; 1KYQ A; 2NUG A; 2VE7 C; 4DV6 E; 1QNT A; 2GPI A; 4DV4 E; 2D9H A; 1X47 A; 2LUQ A; 1YYO A; 2DIX A; 1UN6 B; 4X9J A; 4LTY A; 5LLQ A; 2CSH A; 1XMQ E; 2ENC A; 2RS7 A; 2WBT A; 4R2A A; 1ZBQ A; 4X65 E; 1YUI A; 2YSO A; 2MC6 A; 1I94 E; 3C4T A; 1EH8 A; 2V83 A; 4DR7 E; 4DR1 E; 4NXN E; 1BBO A; 4BBY A; 4GZN C; 1EKZ A; 4DUZ E; 4YY3 E; 5ADZ A; 1B69 A; 2B3T B; 3J80 C; 2R1F A; 4DR5 E; 2NUF A; 4DKK A; 2YTN A; 3LML A; 4M2Z A; 2EMC A; 4X8W A; 3VYX A; 3HPZ A; 2EMG A; 4R2P A; 4IS1 C; 2HHH E; 3DF6 A; 2B7V A; 1PJQ A; 4TUG A; 4X64 E; 3MHS C; 1YZ9 A; 2ODR D; 3EQ1 A; 4KZS A; 1FJG E; 4GEQ B; 1T4O A; 2L2M A; 5KL2 A; 2V85 A; 2DMI A; 4X62 E; 4L8N A; 2EL5 A; 4YHH E; 4LU9 A; 1DI2 A; 2EOE A; 1IQO A; 1XNQ E; 2G7H A; 4F2J C; 2ELZ A; 2F4V E; 3KZY A; 4WSG A; 3OTO E; 3C6M A; 4BS9 A; 2EMW A; 1BB8 A; 2JR1 A; 3QG5 C; 1A1L A; 2EOQ A; 3BGH A; 2ZM6 E; 1YPN A; 3ADG A; 1X49 A; 3VYY A; 5IT9 C; 4JI7 E; 5KL4 A; 4GKK E; 2EMZ A; 4B3T E; 4N4R B; 2DLK A; 4DV7 E; 4F6N A; 3JAM C; 2IHR 1; 1Z1B A; 1A1J A; 1UIL A; 2VF1 A; 5AE3 A; 3P1X A; 1NCS A; 2LTR A; 2LJU A; 4DUY E; 2MKD A; 4LFA E; 1EH6 A; 4LFC E; 2YU5 A; 5A2Q C; 5IWA E; 1PDA A; 2V89 A; 5A6K A; 4X66 E; 4WX9 A; 1UBD C; 2CPN A; 4R2E A; 4BMJ A; 4ZYD A; 4JI4 E; 2YTO A; 2UUC E; 2CTD A; 5KL5 A; 1XNR E; 4RHB B; 1GTK A; 4J8Z A; 1HNW E; 1STU A; 1T38 A; 1TF3 A; 2UXC E; 4O43 A; 2JXP A; 2DSY A; 2YRM A; 2F8B A; 1IMU A; 1J26 A; 3J7A G; 5AAS A; 1L4S A; 2JOX A; 1BBG A; 4TUI A; 2EE8 A; 4LF5 E; 1YYW A; 2YTG A; 1FKA E; 2EM9 A; 2GHF A; 3HTX A; 2LTS A; 4K0K E; 3MSW A; 3F6G A; 2M1S A; 1WHQ A; 3IWC A; 3HQ1 A; 2EMI A; 4JI8 E; 2EN6 A; 2LVH A; 2EN3 A; 4IJD A; 3EPL A; 2YWQ A; 4BC9 A; 4L5N C; 5A6J A; 1N33 E; 4F54 A; 4DV2 E; 2EOM A; 2EOS A; 1AAY A; 4O4K A; 4WXD A; 2EPM X; 2YTI A; 1T4L B; 3KWR A; 3UK3 C; 4LF7 E; 4B3R E; 2RTX A; 1TN9 A; 2EM5 A; 1X48 A; 3ADJ A; 5LMU E; 2EMK A; 1A1F A; 2EM0 A; 2NA2 A; 1A1I A; 2YU8 A; 2RQL A; 4R2S A; 1MEY C; 1DQ3 A; 2DB2 A; 2EN7 A; 3T1Y E; 1YUJ A; 4B3M E; 4WYQ B; 1X6E A; 5A6B D; 3VHT B; 2EZ6 A; 2V88 A; 2E1M A; 2EOZ A; 2I13 A; 5A6B A; 4DMI A; 2EL6 A; 4KWY A; 1A1G A; 2EM6 A; 2MDG A; 1N36 E; 4NZV A; 2ADR A; 2EOF A; 4Q28 A; 1WJP A; 4O5G A; 2LO3 A; 4MLV A; 2EWL A; 4LF8 E; 3VK6 A; 2L8T A; 2L3J A; 1RQ0 A; 5F3W A; 4WSP A; 4JI5 E; 2WBS A; 2EMF A; 4F9C B; 1IBM E; 2DRP A; 1UHZ A; 3HXL A; 3AUZ A; 2E5L E; 3AV0 A; 3K6Q A; 2HJJ A; 2ODR C; 2WCC 3; 2MKN A; 1X3C A; 2UUA E; 4JV5 E; 1QU6 A; 4I8O A; 2B7T A; 2K4V A; 2EPL X; 2FGG A; 5T6J A; 4LF9 E; 2YZT A; 3T1H E; 2N3G A; 2UXB E; 5AC5 A; 4MLQ A; 2EPA A; 2L33 A; 5LL6 R; 5DNY A; 1GZ6 A; 1RMD A; 4BC7 A; 5CFF E; 1YYK A; 4M9V C; 5A69 A; 2JPA A; 5TSE A; 2EOR A; 5FLX C; 2LUP B; 1WHN A; 1XMO E; 2DGC A; 2UU9 E; 2RSM A; 2EPN A; 1N34 E; 4R2C A; 2FTX B; 2YTQ A; 4LFB E; 1T39 A; 4JYA E; 1PJS A; 4DR3 E; 4F9B B; 2VQE E; 2R76 A; 5LMN E; 2YTP A; 2L2K B; 4DV5 E; 2LRS A; 2CT1 A; 2EMH A; 2EL4 A; 1ZU1 A; 2N3H A; 2EOO A; 3EPK A; 2DLQ A; 5KL7 A; 2DMY A; 2EM8 A; 5AC4 A; 2KON A; 2LT7 A; 4R8O A; 2YRH A; 4HTG A; 2I9I A; 2EN4 A; 2ENH A; 2EQ3 A; 2EPO A; 2EMX A; 1TF6 A; 2ELY A; 1ZBT A; 4OOG C; 1WRJ A; 1JK2 A; 4ZYG A; 2VRD A; 4R03 A; 1IQS A; 1HNZ E; 4BHC A; 1J5E E; 4LF4 E; 2MDR A; 3C4B A; 4ZYH A; 4R2D A; 2H36 X; 2JWO A; 4BHB A; 2VQF E; 2YTJ A; 2V86 A; 4KHP E; 1P47 A; 1T4N A; 4WXC A; 4P7D A; 4HEI A; 1SR9 A; 2WBU A; 3ADI A; 3RMP A; 2N8X A; 2ENA A; 3MHH C; 4P78 A; 2LV2 A; 2EPC A; 2JP9 A; 3IWB A; 4O24 A; 1G2F C; 2EPP A; 3ECR A; 2LE2 A; 2YRK A; 5IXM B; 2BBG A; 2EPR A; 2M7Q A; 2L6M A; 4OX9 E; 1PJT A; 2V8Q B; 3LLH A; 5AE2 A; 1YFH A; 2JVA A; 2PRT A; 2EJ4 A; 2NUE A; 2RS6 A; 2YPN A; 3C6K A; 1N3G A; 3BID A; 2EQ0 A; 5A6A A; 2EP3 A; 4WFT A; 2EPU A; 3F6H A; 5AE1 A; 2LBS B; 2LJH A; 4DR4 E; 2EQ1 A; 4M0V A; 2HGH A; 2EMA A; 3EPH A; 2EOX A; 2JY9 A; 2KHX A; 1F2I G; 2M9A A; 4WPY A; 2B9D A; 2RPC A; 4DV1 E; 3TQM A; 2LMZ A; 4DR2 E; 4JI3 E; 2L92 A; 4GKJ E; 2EML A; 4ZYE A; 2YSP A; 4R2R A; 3HPS A; 5BR8 E; 1YSA C; 1DGC A; 2WZO A; 1IBL E; 2J7J A; 2EM2 A; 4M30 A; 1HNX E; 3J81 C; 2EN8 A; 2NAB A; 2RSI A; 3FIG A; 2L3C A; 3KZZ A; 2EM4 A; 2FV4 B; 4LF6 E; 2EOI A; 2YTE A; 1WXR A; 4RH8 A; 3BF2 A; 1JK1 A; 4NHR A; 2UUB E; 1X6F A; 5IV8 B; 1SFE A; 2YT4 A; 2EMB A; 2L2N A; 3JTZ A; 5KL6 A; 1NEI A; 2GLI A; 2E72 A; 4FK5 C; 3H09 A; 2JOB A; 1A1H A; 1IBK E; 4JI1 E; 2EN2 A; 2EPZ A; 4JI0 E; 2UXD E; 1RC7 A; 4DV3 E; 4JI6 E; 2HC5 A; 4BCA A; 4F9A B; 3THN A; 4Q35 B; 2BB8 A; 2EOJ A; 2EPX A; 2JYA A; 1N32 E; 3J7Y p; 1A1K A; 2EM7 A; 2A25 A; 2K7I A; 1LLM C; 3ZOQ B; 1GQE A; 2EMY A; 1MGT A; 1AH5 A; 2M4I A; 3BBG A; 2Q8U A; 4JI2 E; 3ADL A; 1HR0 E; 2EOH A; 1G2D C; 2LCE A; 2EOY A; 1EH7 A; 1ZR9 A; 2EPK X; 3DJW A; 3IWD A; 2EN1 A; 3OML A; 1PKP A; 1ZAA C; 4F6M A; 5KL3 A; 2KOU A; 3M99 B; 2YTF A; #chains in the Genus database with same CATH homology 5F3W A; 4WSP A; 2M7Q A; 4AQY E; 2L6M A; 4JI5 E; 1UIL A; 2VF1 A; 4OX9 E; 2V8Q B; 3LLH A; 4F9C B; 5AE3 A; 1UHZ A; 2MC5 A; 3HXL A; 3P1X A; 5AE2 A; 1IBM E; 2JVA A; 2LTR A; 3AUZ A; 2E5L E; 3AV0 A; 3K6Q A; 2NUE A; 2RS6 A; 2ODR C; 4DUY E; 4DR6 E; 4WFT A; 1O0W A; 4B3S E; 3F6H A; 4LFA E; 4NXM E; 5AE1 A; 4DV0 E; 2LJH A; 2LBS B; 4LFC E; 2V87 A; 5A2Q C; 5IWA E; 2UUA E; 1QU6 A; 4M0V A; 2V89 A; 3JU0 A; 4I8O A; 2B7T A; 4JV5 E; 2NUG A; 2K4V A; 2VE7 C; 4X66 E; 2FGG A; 5T6J A; 4LF9 E; 2YZT A; 2CPN A; 3T1H E; 2N3G A; 2JY9 A; 4BMJ A; 4DV6 E; 2UUC E; 4JI4 E; 2UXB E; 4DV4 E; 2KHX A; 2L33 A; 5LL6 R; 1XNR E; 4WPY A; 2B9D A; 1X47 A; 2LUQ A; 4J8Z A; 1HNW E; 1YYO A; 1STU A; 2DIX A; 1GZ6 A; 5DNY A; 2UXC E; 4LTY A; 4DV1 E; 1XMQ E; 2RS7 A; 4JI3 E; 2DSY A; 1ZBQ A; 2LMZ A; 2F8B A; 4BC7 A; 5CFF E; 2L92 A; 4DR2 E; 4X65 E; 1YYK A; 1J26 A; 4GKJ E; 2MC6 A; 3J7A G; 5AAS A; 1I94 E; 3HPS A; 5FLX C; 2LUP B; 3C4T A; 5BR8 E; 1WHN A; 2V83 A; 2JOX A; 2WZO A; 4TUI A; 1XMO E; 1IBL E; 2UU9 E; 4DR7 E; 2RSM A; 4M30 A; 4B3R E; 4LF5 E; 4DR1 E; 4NXN E; 4BBY A; 1YYW A; 1EKZ A; 3J81 C; 1HNX E; 3FIG A; 2L3C A; 1N34 E; 1FKA E; 4DUZ E; 4YY3 E; 3HTX A; 2FV4 B; 2FTX B; 4LF6 E; 4LFB E; 5ADZ A; 2LTS A; 1WXR A; 3MSW A; 4JYA E; 4K0K E; 3F6G A; 4DR3 E; 2B3T B; 2M1S A; 1WHQ A; 3J80 C; 4DR4 E; 3IWC A; 4F9B B; 4DR5 E; 3HQ1 A; 4JI8 E; 2VQE E; 5LMN E; 4DV5 E; 2NUF A; 2YT4 A; 4DKK A; 2L2K B; 2UUB E; 2L2N A; 3LML A; 4M2Z A; 2LRS A; 4X8W A; 3VYX A; 3HPZ A; 2N3H A; 4BC9 A; 4L5N C; 3JTZ A; 2HHH E; 3DF6 A; 2B7V A; 1N33 E; 2DMY A; 4F54 A; 4DV2 E; 2KON A; 4R8O A; 4TUG A; 4X64 E; 1YZ9 A; 2ODR D; 3H09 A; 1T4L B; 3KWR A; 2JOB A; 4KZS A; 1FJG E; 1IBK E; 4JI1 E; 1ZBT A; 4GEQ B; 4OOG C; 4JI0 E; 1T4O A; 2RTX A; 2L2M A; 4DV3 E; 4BCA A; 1RC7 A; 4JI6 E; 4LF7 E; 2UXD E; 1X48 A; 2V85 A; 3ADJ A; 4R03 A; 4F9A B; 5LMU E; 4X62 E; 4L8N A; 2NA2 A; 4YHH E; 4LU9 A; 1HNZ E; 1DI2 A; 1J5E E; 4LF4 E; 1N32 E; 1XNQ E; 3J7Y p; 1DQ3 A; 2G7H A; 2MDR A; 3C4B A; 2DB2 A; 3T1Y E; 4B3M E; 2H36 X; 2JWO A; 2F4V E; 4WYQ B; 2VQF E; 3ZOQ B; 1GQE A; 3OTO E; 2M4I A; 2V88 A; 2EZ6 A; 2V86 A; 2E1M A; 4BS9 A; 4KHP E; 4JI2 E; 3ADL A; 2JR1 A; 1T4N A; 1HR0 E; 4DMI A; 4P7D A; 1SR9 A; 2ZM6 E; 3ADG A; 1X49 A; 3VYY A; 5IT9 C; 3ADI A; 3RMP A; 4JI7 E; 1N36 E; 4GKK E; 3DJW A; 4P78 A; 4Q28 A; 4B3T E; 3IWD A; 3OML A; 4DV7 E; 1PKP A; 2EWL A; 4LF8 E; 3VK6 A; 2L8T A; 3IWB A; 2KOU A; 3JAM C; 2L3J A; 1RQ0 A; 2IHR 1; 2LE2 A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
