The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
42
|
sequence length |
171
|
structure length |
166
|
Chain Sequence |
EMKRTTLDSPLGKLELSGCEQGLHEIKLLGKDAVEVPAPAAVLGGPEPLMQCTAWLNAYFHQPEAIEEFPVPALHHPVFQQESFTRQVLWKLLKVVKFGEVISYQQLAALAGNPKAARAVGGAMRGNPVPILIPCHRVVCSSGAVGNYSGGLAVKEWLLAHEGHRL
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
publication title |
Crystal Structure of the Human O(6)-Alkylguanine-DNA Alkyltransferase.
pubmed doi rcsb |
molecule tags |
Dna repair
|
source organism |
Homo sapiens
|
molecule keywords |
METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE
|
total genus |
42
|
structure length |
166
|
sequence length |
171
|
ec nomenclature |
ec
2.1.1.63: Methylated-DNA--[protein]-cysteine S-methyltransferase. |
pdb deposition date | 1999-10-20 |
chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
---|---|---|---|
A | PF01035 | DNA_binding_1 | 6-O-methylguanine DNA methyltransferase, DNA binding domain |
A | PF02870 | Methyltransf_1N | 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain |
cath code
| Class | Architecture | Topology | Homology | Domain |
---|---|---|---|---|---|
Mainly Alpha | Orthogonal Bundle | Arc Repressor Mutant, subunit A | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | ||
Alpha Beta | 2-Layer Sandwich | Double Stranded RNA Binding Domain | Methylated DNA-protein cysteine methyltransferase domain |