The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
40
|
sequence length |
175
|
structure length |
165
|
Chain Sequence |
CEMKRTTLDSPLGKLELSGCEQGLHEIKLLGEVPAPAAVLGGPEPLMQCTAWLNAYFHQPEAIEEFPVPALHHPVFQQESFTRQVLWKLLKVVKFGEVISYQQLAALAGNPKAARAVGGAMRGNPVPILIPHRVVCSSGAVGNYSGGLAVKEWLLAHEGHRLGKP
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding.
pubmed doi rcsb |
| molecule tags |
Transferase
|
| source organism |
Homo sapiens
|
| molecule keywords |
O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE
|
| total genus |
40
|
| structure length |
165
|
| sequence length |
175
|
| ec nomenclature |
ec
2.1.1.63: Methylated-DNA--[protein]-cysteine S-methyltransferase. |
| pdb deposition date | 2000-02-18 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01035 | DNA_binding_1 | 6-O-methylguanine DNA methyltransferase, DNA binding domain |
| A | PF02870 | Methyltransf_1N | 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Arc Repressor Mutant, subunit A | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | ||
| Alpha Beta | 2-Layer Sandwich | Double Stranded RNA Binding Domain | Methylated DNA-protein cysteine methyltransferase domain |
