The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
9
|
sequence length |
79
|
structure length |
79
|
Chain Sequence |
NDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQM
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Solution structure of the Drosha double-stranded RNA-binding domain.
pubmed doi rcsb |
| molecule keywords |
Ribonuclease 3
|
| molecule tags |
Gene regulation,nuclear protein
|
| source organism |
Homo sapiens
|
| total genus |
9
|
| structure length |
79
|
| sequence length |
79
|
| ec nomenclature |
ec
3.1.26.3: Ribonuclease III. |
| pdb deposition date | 2009-04-13 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00035 | dsrm | Double-stranded RNA binding motif |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | Double Stranded RNA Binding Domain | Double Stranded RNA Binding Domain |
#chains in the Genus database with same CATH superfamily 5BR8 E; 1RQ0 A; 5IWA E; 1N36 E; 2RTX A; 3LLH A; 2N3G A; 1PKP A; 1IBK E; 1WHN A; 4DV3 E; 1X47 A; 4DR2 E; 1HNZ E; 4M2Z A; 4JI6 E; 2LTS A; 2JVA A; 1YZ9 A; 2DB2 A; 1EKZ A; 2KHX A; 4GKK E; 1N32 E; 1UIL A; 2DMY A; 4K0K E; 4LF8 E; 1X48 A; 2L2N A; 4JI3 E; 4DV5 E; 4DR1 E; 3ADG A; 1XMO E; 2L33 A; 4LF6 E; 2LTR A; 4DV4 E; 4JI1 E; 1FJG E; 1N34 E; 2UUC E; 2L2K B; 3VYY A; 2L2M A; 1T4L B; 1N33 E; 4JI0 E; 1T4N A; 2RSM A; 4JI4 E; 3ADI A; 4DV0 E; 4AQY E; 1XNR E; 3ADJ A; 2EZ6 A; 1RC7 A; 4JI2 E; 2E5L E; 5CFF E; 1ZBT A; 1STU A; 1I94 E; 2YT4 A; 4OOG C; 4JI8 E; 2B3T B; 4DUY E; 4OX9 E; 4DR3 E; 4LFC E; 2DIX A; 3C4B A; 2VQE E; 2NUE A; 1WHQ A; 4DV7 E; 2NUG A; 4WFT A; 2UUB E; 1XNQ E; 3OTO E; 1O0W A; 3VYX A; 2UXB E; 4GKJ E; 2NA2 A; 1IBL E; 2LUQ A; 3P1X A; 4B3M E; 2RS7 A; 2LJH A; 3T1Y E; 4X8W A; 1YYW A; 2UU9 E; 4X66 E; 4JYA E; 4LFB E; 2JY9 A; 1HR0 E; 4B3T E; 1GQE A; 1X49 A; 4JI7 E; 5LMN E; 1QU6 A; 4DV1 E; 2B7T A; 2LUP B; 2RS6 A; 4X65 E; 4WYQ B; 3T1H E; 4DKK A; 1FKA E; 1HNX E; 4LF5 E; 1IBM E; 4X62 E; 3HTX A; 1DI2 A; 5LMU E; 1XMQ E; 4NXN E; 4JV5 E; 4LF7 E; 2L3J A; 2HHH E; 2LBS B; 3J7Y p; 2F4V E; 4NXM E; 4LFA E; 2CPN A; 2NUF A; 2UXD E; 1T4O A; 4DV6 E; 1YYK A; 2ZM6 E; 1HNW E; 4M30 A; 4YHH E; 1YYO A; 4B3R E; 2N3H A; 1J5E E; 4KHP E; 2MDR A; 4LF4 E; 2VQF E; 2UXC E; 1J26 A; 4DR4 E; 4LF9 E; 4JI5 E; 4DUZ E; 2UUA E; 3C4T A; 2B7V A; 2L3C A; 2LRS A; 4DR5 E; 4B3S E; 2IHR 1; 1UHZ A; 4DR7 E; 3ADL A; 4X64 E; 4DV2 E; 4DR6 E; 4YY3 E; #chains in the Genus database with same CATH topology 3M99 B; 4IS1 C; 2JWO A; 2EJ4 A; 4R2C A; 4DV3 E; 4DR2 E; 1ZAA C; 4M2Z A; 5FLX C; 4JI6 E; 3HPS A; 2JVA A; 1EKZ A; 2GHF A; 2YSP A; 4O4K A; 4P7D A; 2DMY A; 4F9C B; 2I9I A; 1X3C A; 2EN1 A; 3ADG A; 2EN3 A; 4FK5 C; 1N33 E; 2EMY A; 1T4N A; 5A2Q C; 5A6A A; 3AV0 A; 2YSO A; 1SFE A; 2M4I A; 2E5L E; 2ENC A; 2YT4 A; 2EMW A; 1PJS A; 1BB8 A; 1SR9 A; 2EMC A; 2DIX A; 2FGG A; 2DSY A; 2YTG A; 3DJW A; 2EN8 A; 2UUB E; 1XNQ E; 3VYX A; 2EM9 A; 5AE1 A; 2HGH A; 2LUQ A; 3J80 C; 4KZS A; 4BCA A; 2LJH A; 3T1Y E; 2BBG A; 2UU9 E; 4KWY A; 4O5G A; 5A6B D; 1PJT A; 4X66 E; 4JYA E; 4F9A B; 4LFB E; 1EH7 A; 4JI7 E; 2YTQ A; 2B7T A; 4R2S A; 2RS6 A; 4X65 E; 4WYQ B; 2GPI A; 2M7Q A; 3EPL A; 4X62 E; 1IBM E; 4BHB A; 2EMA A; 5LMU E; 1A1L A; 2WZO A; 2LBS B; 3J7Y p; 4NXM E; 3EPK A; 2NUF A; 2EOR A; 4DV6 E; 3MSW A; 2LCE A; 2K4V A; 1A1H A; 4M30 A; 5AE3 A; 2EMB A; 2YRH A; 3QG5 C; 5AC4 A; 4YHH E; 1YYO A; 3JAM C; 1WXR A; 5AAS A; 4F2J C; 2JOX A; 2MDR A; 4O24 A; 4LF4 E; 2EPP A; 2UXC E; 2D9H A; 4LF9 E; 4DUZ E; 4BC9 A; 2EMX A; 2EM3 A; 4YY3 E; 2EPN A; 2MC5 A; 1PJQ A; 1RQ0 A; 2JYA A; 2RTX A; 4I8O A; 5IWA E; 1BBG A; 2PRT A; 1N36 E; 2EPU A; 2EQ1 A; 2EMI A; 2ELY A; 5KL2 A; 1X47 A; 5A69 A; 3KWR A; 2EOF A; 2VF1 A; 1DGC A; 3ZOQ B; 2LT7 A; 2YWQ A; 2EOZ A; 2EP3 A; 2KHX A; 2YTD A; 4MLV A; 1G2F C; 3H09 A; 1N32 E; 4WSG A; 2L92 A; 2V89 A; 4J8Z A; 3C6M A; 1KJK A; 1X48 A; 2ODR D; 2YZT A; 4DV5 E; 2RSI A; 2V83 A; 1ZU1 A; 4N4R B; 1XMO E; 2L33 A; 2LJU A; 4NHR A; 3THO B; 1A1K A; 1TF6 A; 2EL6 A; 2DGC A; 4LF6 E; 1L4S A; 3DF6 A; 2EN4 A; 2L2K B; 2RQL A; 2RSM A; 4DV0 E; 2EM7 A; 3F6G A; 2EM2 A; 1YUJ A; 1WJP A; 1RC7 A; 4MLQ A; 2EM4 A; 1IQO A; 4ZYE A; 3TQM A; 4L5N C; 4R2R A; 2FV4 B; 2M9A A; 4DUY E; 2ENH A; 4DR3 E; 2EMK A; 2FTX B; 1WHQ A; 3IWD A; 4DV7 E; 2EE8 A; 3J7A G; 2UXB E; 1X6H A; 2WBT A; 1NEI A; 1IBL E; 5A6K A; 1AH5 A; 1ZBQ A; 4LTY A; 1B69 A; 4IJD A; 5LLQ A; 2EWL A; 1TF3 A; 1AAY A; 2EOY A; 2EML A; 3JTZ A; 2JY9 A; 1HR0 E; 2V85 A; 2YTI A; 2EPZ A; 1FKA E; 2JOB A; 3BBG A; 1HNX E; 4BS9 A; 2ENA A; 2EOI A; 1DI2 A; 1N3G A; 4JV5 E; 2L3J A; 1DQ3 A; 2EPK X; 2HJJ A; 3MHS C; 1T4O A; 1YFH A; 2HC5 A; 4HTG A; 2DMI A; 1HNW E; 5KL3 A; 1J5E E; 1UBD C; 2EOJ A; 2EOH A; 2YU5 A; 2LV2 A; 4R2E A; 1J26 A; 2UUA E; 1MGT A; 3C4T A; 2EPX A; 2A25 A; 1UHZ A; 1T39 A; 4X64 E; 2K7I A; 3HXL A; 2YTN A; 4DV2 E; 4R03 A; 4WX9 A; 2YPN A; 2LE2 A; 4BHC A; 1YSA C; 2MKD A; 5IXM B; 1NCS A; 3LLH A; 5IV8 B; 3AUZ A; 2E72 A; 3KZY A; 2V86 A; 1HNZ E; 1PDA A; 2LTS A; 2YTJ A; 2M1S A; 2L8T A; 1YZ9 A; 2WBU A; 2DB2 A; 3EPH A; 4DMI A; 2LVH A; 3F6H A; 4LF8 E; 2L2N A; 4BC7 A; 4JI3 E; 1GTK A; 5TSE A; 1JK1 A; 4DR1 E; 2LTR A; 4Q28 A; 4DV4 E; 3RMP A; 1FJG E; 1N34 E; 3VYY A; 1T4L B; 4JI0 E; 3L00 A; 4JI4 E; 5KL7 A; 2KON A; 2EMH A; 1TN9 A; 5AE2 A; 3BGH A; 2ODR C; 1IMU A; 2EMZ A; 2EOX A; 1A1G A; 3JU0 A; 1IQS A; 3EQ1 A; 2DRP A; 5CFF E; 1ZBT A; 1STU A; 3UK3 C; 2G7H A; 4OOG C; 2B3T B; 2ADR A; 2DLK A; 4OX9 E; 3C4B A; 2VQE E; 2NUE A; 2YTP A; 4RHB B; 4WFT A; 1O0W A; 2JXP A; 2LMZ A; 3VK6 A; 2JR1 A; 1YUI A; 4GZN C; 2EM0 A; 2Q8U A; 4HEI A; 2JPA A; 2EOM A; 4B3M E; 2BB8 A; 2EM5 A; 4ZYD A; 1YYW A; 4WXD A; 2I13 A; 5ADZ A; 2CTD A; 1GQE A; 1X49 A; 2EL4 A; 2LUP B; 1QU6 A; 5KL5 A; 2MKN A; 3BID A; 4LF5 E; 2EN2 A; 2YRM A; 2EPL X; 2CT1 A; 3HTX A; 1XMQ E; 4TUI A; 2E1M A; 2F4V E; 2EQ3 A; 3HPZ A; 2YTE A; 4LFA E; 4ZYG A; 2EPA A; 1JK2 A; 1Z1B A; 1G2D C; 4O43 A; 4F9B B; 2EN7 A; 2V87 A; 5DNY A; 3MHH C; 1YPN A; 3BF2 A; 2EMG A; 4B3R E; 2N3H A; 2MDG A; 3K6Q A; 2VQF E; 1EH6 A; 2EM6 A; 2WBS A; 2F8B A; 1F2I G; 1RMD A; 2B7V A; 2L3C A; 4DR5 E; 4B3S E; 2EPC A; 4M9V C; 4TUG A; 4DR7 E; 4Q35 B; 4NZV A; 3ADL A; 5BR8 E; 1EH8 A; 1QNT A; 4R2Q A; 4R2D A; 3C6K A; 2N3G A; 2DLQ A; 1PKP A; 1IBK E; 3HQ1 A; 1WHN A; 1X6F A; 2EM8 A; 3FIG A; 4R8O A; 4WPY A; 2EOE A; 4P78 A; 3IWB A; 2EL5 A; 2ELZ A; 1P47 A; 5AC5 A; 2KOU A; 4GKK E; 4F54 A; 2N8X A; 1UIL A; 4K0K E; 4WXC A; 1GZ6 A; 2MC6 A; 4JI1 E; 2UUC E; 1A1I A; 2L2M A; 3IWC A; 3ADI A; 2B9D A; 2V8Q B; 4AQY E; 2WCC 3; 1XNR E; 1BBO A; 3ADJ A; 2EZ6 A; 2YRK A; 2GLI A; 5IT9 C; 2EN6 A; 4JI2 E; 5A6J A; 1I94 E; 4BMJ A; 4JI8 E; 4LFC E; 2EOO A; 3KZZ A; 2R1F A; 2JP9 A; 2NUG A; 1LLM C; 3OTO E; 4F6N A; 1A1F A; 4GKJ E; 2NA2 A; 5KL6 A; 4F6M A; 4ZYH A; 3P1X A; 2VRD A; 2RS7 A; 2VE7 C; 2L6M A; 2R76 A; 4RH8 A; 4X8W A; 1A1J A; 2LO3 A; 1KYQ A; 2EPO A; 3THN A; 4R2P A; 4M0V A; 4LU9 A; 2H36 X; 4WSP A; 4B3T E; 4BBY A; 4DV1 E; 3LML A; 5LMN E; 1X5W A; 1UN6 B; 2NAB A; 3ECR A; 3T1H E; 4DKK A; 3OML A; 2CSH A; 4L8N A; 2EMF A; 4NXN E; 4LF7 E; 2HHH E; 4R2A A; 1X6E A; 2CPN A; 1T38 A; 1ZR9 A; 2UXD E; 1YYK A; 2YU8 A; 2ZM6 E; 5F3W A; 5T6J A; 5A6B A; 2RPC A; 4KHP E; 3EPJ A; 3VHT B; 2EPM X; 3J81 C; 2J7J A; 2V88 A; 4GEQ B; 2EQ0 A; 5LL6 R; 2YTF A; 4X9J A; 4DR4 E; 4DR6 E; 4JI5 E; 1MEY C; 1WRJ A; 5KL4 A; 2EOS A; 2LRS A; 2IHR 1; 2EOQ A; 2EPR A; 2YTO A; #chains in the Genus database with same CATH homology 5BR8 E; 2LE2 A; 1RQ0 A; 4I8O A; 5IWA E; 2RTX A; 1N36 E; 2JWO A; 3LLH A; 2N3G A; 1PKP A; 1IBK E; 3AUZ A; 3HQ1 A; 1WHN A; 2V86 A; 3FIG A; 1X47 A; 4R8O A; 4DV3 E; 4DR2 E; 4WPY A; 1HNZ E; 3KWR A; 2VF1 A; 4P78 A; 4M2Z A; 5FLX C; 4JI6 E; 3HPS A; 3IWB A; 2LTS A; 3ZOQ B; 2JVA A; 2L8T A; 2M1S A; 1YZ9 A; 2DB2 A; 1EKZ A; 2KOU A; 4P7D A; 2KHX A; 4GKK E; 3H09 A; 4F54 A; 4DMI A; 1N32 E; 1UIL A; 3F6H A; 2L92 A; 2DMY A; 2V89 A; 4F9C B; 4K0K E; 4J8Z A; 4LF8 E; 1X48 A; 2ODR D; 2L2N A; 2YZT A; 4BC7 A; 4JI3 E; 4DV5 E; 4DR1 E; 2V83 A; 3ADG A; 1XMO E; 1GZ6 A; 2L33 A; 4LF6 E; 2LTR A; 2MC6 A; 4Q28 A; 4DV4 E; 3RMP A; 3DF6 A; 4JI1 E; 1FJG E; 1N34 E; 2UUC E; 2L2K B; 3VYY A; 2L2M A; 1T4L B; 1N33 E; 3IWC A; 4JI0 E; 1T4N A; 2RSM A; 4JI4 E; 3ADI A; 2B9D A; 4DV0 E; 3F6G A; 2V8Q B; 5A2Q C; 4AQY E; 3AV0 A; 1XNR E; 2KON A; 3ADJ A; 2EZ6 A; 5AE2 A; 1RC7 A; 2ODR C; 2M4I A; 3JU0 A; 5IT9 C; 4JI2 E; 2E5L E; 4L5N C; 5CFF E; 1ZBT A; 1STU A; 1I94 E; 4BMJ A; 2FV4 B; 2G7H A; 2YT4 A; 4OOG C; 2B3T B; 4JI8 E; 4DUY E; 4OX9 E; 4DR3 E; 4LFC E; 1SR9 A; 2DIX A; 3C4B A; 2VQE E; 2FGG A; 2DSY A; 2FTX B; 1WHQ A; 3IWD A; 4DV7 E; 2NUE A; 3DJW A; 2NUG A; 4WFT A; 2UUB E; 1XNQ E; 3OTO E; 1O0W A; 3J7A G; 2LMZ A; 3VYX A; 3VK6 A; 2UXB E; 2JR1 A; 5AE1 A; 2NA2 A; 4GKJ E; 1IBL E; 2LUQ A; 1ZBQ A; 3P1X A; 4KZS A; 3J80 C; 4LTY A; 4B3M E; 2RS7 A; 2VE7 C; 2L6M A; 4BCA A; 2LJH A; 3T1Y E; 2EWL A; 4X8W A; 1YYW A; 2UU9 E; 4X66 E; 4JYA E; 5ADZ A; 4F9A B; 4M0V A; 4LU9 A; 2H36 X; 3JTZ A; 2JY9 A; 4WSP A; 2V85 A; 1HR0 E; 4B3T E; 4LFB E; 1GQE A; 1X49 A; 3LML A; 4JI7 E; 1QU6 A; 4BBY A; 2B7T A; 5LMN E; 4DV1 E; 2LUP B; 2RS6 A; 4X65 E; 4WYQ B; 2JOB A; 4DKK A; 3OML A; 3T1H E; 1FKA E; 2M7Q A; 4BS9 A; 4X62 E; 4L8N A; 1HNX E; 1IBM E; 4LF5 E; 5LMU E; 3HTX A; 1DI2 A; 1XMQ E; 4NXN E; 4JV5 E; 4TUI A; 2E1M A; 2WZO A; 2L3J A; 2LBS B; 3J7Y p; 1DQ3 A; 2HHH E; 4LF7 E; 4NXM E; 2F4V E; 3HPZ A; 4LFA E; 2CPN A; 2NUF A; 2UXD E; 1T4O A; 4F9B B; 4DV6 E; 3MSW A; 1YYK A; 2K4V A; 2ZM6 E; 5F3W A; 2V87 A; 5DNY A; 5T6J A; 4M30 A; 5AE3 A; 1HNW E; 4YHH E; 1YYO A; 4B3R E; 2N3H A; 3JAM C; 1J5E E; 4KHP E; 1WXR A; 5AAS A; 3J81 C; 2JOX A; 2MDR A; 2V88 A; 4GEQ B; 5LL6 R; 3K6Q A; 4LF4 E; 2VQF E; 2UXC E; 1J26 A; 4DR4 E; 4LF9 E; 4JI5 E; 2F8B A; 4DUZ E; 2UUA E; 3C4T A; 2B7V A; 2L3C A; 2LRS A; 4BC9 A; 4DR5 E; 2IHR 1; 4B3S E; 4TUG A; 1UHZ A; 4DR7 E; 3ADL A; 4X64 E; 3HXL A; 4DV2 E; 4DR6 E; 4YY3 E; 4R03 A; 2MC5 A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
