1YYOA

Crystal structure of rnase iii mutant e110k from aquifex aeolicus complexed with double-stranded rna at 2.9-angstrom resolution
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
220
structure length
220
Chain Sequence
MKMLEQLEKKLGYTFKDKSLLEKALTHVSYSKKEHYETLEFLGDALVNFFIVDLLVQYSPNKREGFLSPLKAYLISEEFFNLLAQKLELHKFIRIKRGKINETIIGDVFKALWAAVYIDSGRDANFTRELFYKLFKEDILSAIKEGRVKKDYKTILQEITQKRWKERPEYRLISVEGPHHKKKFIVEAKIKEYRTLGEGKSKKEAEQRAAEELIKLLEES
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Intermediate states of ribonuclease III in complex with double-stranded RNA
pubmed doi rcsb
molecule tags Hydrolase/rna
source organism Aquifex aeolicus
molecule keywords 5'-R(*CP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*G)-3'
total genus 66
structure length 220
sequence length 220
chains with identical sequence B
ec nomenclature ec 3.1.26.3: Ribonuclease III.
pdb deposition date 2005-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00035 dsrm Double-stranded RNA binding motif
A PF00636 Ribonuclease_3 Ribonuclease III domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1520.10 Mainly Alpha Orthogonal Bundle Ribonuclease iii, N-terminal Endonuclease Domain; Chain A Ribonuclease III domain 1yyoA01
3.30.160.20 Alpha Beta 2-Layer Sandwich Double Stranded RNA Binding Domain Double Stranded RNA Binding Domain 1yyoA02
2LUPB 1RQ0A 1N32E 4M2ZA 4JI8E 1UILA 4DV2E 2N3HA 4JI0E 4OOGC 2UXBE 2LBSB 2IHR1 5IWAE 3T1YE 4DR7E 3VYYA 1XNRE 1N36E 1QU6A 3RV0A 2VQFE 2UU9E 4LFCE 4DR1E 2KHXA 4JI7E 3O2RA 1FKAE 4DV4E 4DR3E 3C4TA 2GSLA 2UXCE 4LFAE 2UUAE 5BR8E 4OUNA 2NUGA 1HNZE 4OX9E 1STUA 1N34E 4X65E 1IBKE 5LMUE 4LF8E 4X66E 2JVAA 1WHQA 2DIXA 1RC5A 4DUZE 4B3RE 2NUEA 1XMQE 4GKKE 2FFLA 4AQYE 2N3GA 4KHPE 1DI2A 4LF9E 1XMOE 1WHNA 2RS6A 3ADJA 4JI5E 5LMNE 1HNWE 1X49A 4B3TE 2LUQA 4JI1E 4X64E 4JI2E 4WYQB 4DV5E 1HR0E 4YHHE 3LLHA 2MDRA 1YYOA 2RTXA 1HNXE 4DV1E 1IBLE 4LF5E 4JI6E 2ZM6E 5CFFE 2UUBE 3P1XA 4WFTA 1FJGE 4X8WA 4JV5E 1YYWA 3O2RB 1YYKA 2LTSA 2A11A 2L3JA 1YZ9A 2B7TA 2B7VA 4X62E 4DR5E 2DMYA 1T4OA 2L33A 2VQEE 3HTXA 3J7Yp 2L2MA 2L2KB 4DR4E 4DUYE 4DKKA 4JYAE 2JY9A 4K0KE 2L2NA 2YT4A 4DV7E 3ADGA 4JI4E 2NA2A 3N3WA 4GKJE 2F4VE 2UUCE 3T1HE 2NUFA 3RV1A 2RSMA 2B3TB 2HHHE 4DR2E 2CPNA 2DB2A 2EZ6A 1PKPA 4LF6E 1X47A 3OTOE 2LTRA 4B3SE 1N33E 2QVWA 1JFZA 4LF7E 1IBME 4B3ME 4JI3E 1XNQE 4DV0E 2LRSA 4NXME 4NXNE 3VYXA 2UXDE 4LF4E 1J26A 4YY3E 1RC7A 2RS7A 4DR6E 1UHZA 4DV6E 2E5LE 2LJHA 1T4NA 1T4LB 3ADIA 3C4BA 1X48A 1J5EE 1I94E 1EKZA 1O0WA 2EB1A 4M30A 2L3CA 1I4SA 1ZBTA 4LFBE 4DV3E 3ADLA 1U61A 1GQEA
chains in the Genus database with same CATH superfamily
5LL6R 3DF6A 5ADZA 2JXPA 2EM2A 2CTDA 2LBSB 3THOB 1TN9A 1F2IG 4DR7E 2EMLA 3VYYA 4J8ZA 1LLMC 1AH5A 2VQFE 2M4IA 2KHXA 3HPSA 3O2RA 3C4TA 3EPJA 2GSLA 2ODRC 4KZSA 2LCEA 2G7HA 2L8TA 2EMHA 2MC5A 5BR8E 2JR1A 1HNZE 2NABA 5KL3A 1IBKE 5LMUE 2VF1A 5F3WA 4LF8E 4L8NA 4FK5C 2JVAA 2EOMA 4O43A 4AQYE 4KHPE 5FLXC 2EM8A 2WZOA 3ADJA 2EOOA 2WCC3 1HNWE 5KL2A 1RMDA 1X3CA 4JI1E 2RQLA 3EPHA 4WYQB 2GLIA 4BHBA 1EH7A 2RTXA 2EORA 1ZBQA 2JYAA 4WX9A 1A1KA 2RSIA 1IBLE 2DGCA 4JI6E 2M9AA 5CFFE 3BIDA 3P1XA 2YRHA 4WFTA 2LT7A 1FJGE 4X8WA 1L4SA 2LTSA 2YTOA 2B7TA 4KWYA 3QG5C 4DR5E 2L33A 1T4OA 2HGHA 3J7Yp 2L2MA 4TUGA 3LMLA 4DR4E 1IQOA 2YTJA 4JYAE 1YSAC 2EP3A 4I8OA 2EPUA 3T1HE 3THNA 2WBTA 4RH8A 2B3TB 1A1GA 4M9VC 4ZYHA 3JU0A 2CPNA 2EZ6A 2YTFA 3OTOE 3HXLA 2JWOA 2EMKA 1JFZA 2BBGA 2EE8A 3ZOQB 1YPNA 4LF7E 3KZZA 4JI3E 1XNQE 2LRSA 3VYXA 4LF4E 2EPRA 4DR6E 2RS7A 2E5LE 1J5EE 2EL5A 2R1FA 2EOJA 4BHCA 2V89A 4RHBB 4R2PA 2V86A 5DNYA 4DV3E 3ADLA 1NCSA 1RQ0A 2EN1A 5KL7A 4Q28A 2N3HA 2UXBE 2B9DA 2MKDA 3MHHC 3T1YE 2DMIA 1XNRE 2DLKA 3BBGA 2YRKA 4BC7A 5A6BA 2EOIA 2UU9E 3OMLA 1BBOA 2K7IA 1MEYC 2EQ0A 2EOSA 5KL5A 4LFCE 4DR1E 3L00A 1QNTA 2FGGA 2UXCE 2ENHA 2D9HA 3JAMC 2EOQA 1ZTDA 2YWQA 1GZ6A 1YFHA 4P78A 4X65E 2FV4B 2J7JA 2YU5A 3FIGA 1WXRA 1UN6B 2EMGA 1RC5A 1PJTA 5AASA 2EOEA 4DUZE 1A1JA 5KL4A 2EPMX 3RMPA 1XMOE 2LV2A 1EH8A 2N8XA 4O24A 2EPLX 3MSWA 4BC9A 4B3TE 2EM4A 4JI2E 3VK6A 4ZYDA 4BCAA 3LLHA 3AUZA 1YYOA 3C6MA 1T39A 2EOXA 2ZM6E 2EM3A 2JP9A 4F9BB 3J81C 1G2DC 2K4VA 1YYKA 2L3JA 2I9IA 2H36X 1GTKA 4WSPA 3HTXA 1PJSA 4F6NA 2EN7A 1PDAA 3UK3C 2EL6A 1JK1A 4R2RA 4DKKA 1KYQA 2Q8UA 4LU9A 4K0KE 5A6BD 3ADGA 2JOBA 2NA2A 1DGCA 4X9JA 4GKJE 2V8QB 4R2DA 2VE7C 2NUFA 2CT1A 2EMZA 2HHHE 2ADRA 4DR2E 5TSEA 5AE3A 1PKPA 2L6MA 1X5WA 1X47A 4LF6E 4F2JC 2QVWA 1B69A 2EM9A 2EN4A 4MLVA 1SR9A 4ZYEA 4WXCA 1J26A 1KJKA 1RC7A 1DQ3A 2EPPA 2KONA 2LJHA 2ELZA 1T4LB 3ADIA 1YUJA 4R03A 1I94E 3IWCA 2YSPA 1O0WA 5IV8B 2KOUA 3IWBA 4M30A 3F6HA 2L3CA 1I4SA 1Z1BA 4LFBE 5T6JA 2LUPB 3J7AG 3K6QA 1X6FA 4M2ZA 4JI8E 4DV2E 2LVHA 2YU8A 2IHR1 1N3GA 4R2EA 4F9AB 4L5NC 4R8OA 1QU6A 3RV0A 4BMJA 4WXDA 4JI7E 1FKAE 4DV4E 2MKNA 4WSGA 3AV0A 3EPKA 2R76A 4LFAE 1WJPA 2RPCA 2EPAA 2MDGA 1ZU1A 3EQ1A 3M99B 4OUNA 2NUGA 4R2CA 1G2FC 1STUA 2M1SA 1YUIA 4OX9E 1JK2A 2EPCA 1WHQA 2NUEA 2YZTA 1NEIA 1XMQE 1A1HA 4GKKE 3H09A 4LF9E 1ZR9A 2RS6A 1X6EA 5AE1A 4JI5E 1EH6A 2EMAA 5LMNE 1A1LA 2I13A 2V85A 4IJDA 5KL6A 3F6GA 4M0VA 2HJJA 2E1MA 4DV5E 3C6KA 1HR0E 2PRTA 4MLQA 2V83A 1ZAAC 1TF6A 2EM7A 1BBGA 2EMFA 5A6JA 4R2QA 2ELYA 3IWDA 1YZ9A 2YTPA 4BS9A 4GZNC 2EN8A 2ENCA 2B7VA 4WPYA 4X62E 2DMYA 2VQEE 2EL4A 2DLQA 2EOFA 2L2KB 2DSYA 1MGTA 2EMIA 4GEQB 5AC4A 5IXMB 3ECRA 2YT4A 2EPNA 4JI4E 2E72A 2YTDA 2WBUA 2F4VE 3RV1A 2RSMA 3VHTB 2YTEA 4HEIA 2GHFA 2V87A 4B3SE 1N33E 2ENAA 1IBME 4DV0E 2EPOA 4F9CB 4NXME 2UXDE 4YY3E 4DV6E 2YTNA 4P7DA 4Q35B 4NHRA 1A1IA 4IS1C 2F8BA 2EN3A 3KWRA 2EN2A 1U61A 2EOZA 4O5GA 1GQEA 1P47A 1N32E 4O4KA 1UILA 2EMBA 2EPXA 1BB8A 4JI0E 4LTYA 4OOGC 2DRPA 2BB8A 5IWAE 1IQSA 2EM5A 1N36E 2LJUA 2ODRD 4R2AA 2LMZA 4DR3E 2LE2A 2HC5A 2L92A 2EOYA 2EPKX 2UUAE 3HPZA 1N34E 4X66E 2DIXA 2EOHA 4B3RE 1SFEA 2FFLA 2N3GA 1DI2A 1IMUA 1TF3A 5AE2A 1WHNA 1A1FA 2M7QA 1X49A 3BGHA 2EMCA 2GPIA 2LUQA 5A2QC 1PJQA 2EQ3A 2YTIA 4X64E 2EMYA 4YHHE 3JTZA 2MDRA 1HNXE 2EJ4A 3HQ1A 4DV1E 2EN6A 5AC5A 4LF5E 4BBYA 4R2SA 2YTGA 2UUBE 5A6AA 4JV5E 1YYWA 3O2RB 2EMXA 2EPZA 2EM0A 1AAYA 2A11A 1X6HA 3BF2A 1UBDC 3MHSC 2EQ1A 2EMWA 2A25A 4DUYE 4TUIA 2JY9A 2JPAA 2L2NA 4DV7E 3TQMA 3N3WA 4NZVA 3J80C 1WRJA 2CSHA 2YPNA 2UUCE 2V88A 3KZYA 4ZYGA 2DB2A 2LTRA 2YTQA 4DMIA 5LLQA 2LO3A 4N4RB 4F54A 4B3ME 3EPLA 5IT9C 2WBSA 4F6MA 2YRMA 4NXNE 1T38A 5A6KA 1UHZA 2EWLA 1T4NA 2VRDA 3C4BA 1X48A 1EKZA 3DJWA 2EB1A 5A69A 2EM6A 2MC6A 1ZBTA 2YSOA 2JOXA 2FTXB 4HTGA
chains in the Genus database with same CATH topology
2LUPB 1RQ0A 5LL6R 1N32E 3J7AG 3DF6A 3K6QA 5ADZA 4M2ZA 4JI8E 1UILA 4DV2E 4Q28A 2N3HA 4JI0E 4LTYA 4OOGC 2UXBE 2LBSB 2IHR1 2B9DA 4F9AB 5IWAE 3T1YE 3VYYA 4L5NC 4DR7E 1XNRE 4R8OA 4J8ZA 4BC7A 1N36E 1QU6A 3RV0A 4BMJA 2VQFE 1U61A 2ODRD 2UU9E 3OMLA 4LFCE 2M4IA 4DR1E 4DR6E 2KHXA 3HPSA 4JI7E 3O2RA 2LMZA 4DV4E 2LE2A 3C4TA 4DR3E 2FGGA 2GSLA 2ODRC 3AV0A 1FKAE 2UXCE 4KZSA 4LFAE 2L92A 2G7HA 2L8TA 3JAMC 2UUAE 2MC5A 5BR8E 4OUNA 2NUGA 2JR1A 3HPZA 1STUA 2M1SA 1N34E 1GZ6A 1HNZE 4P78A 4X65E 2FV4B 3FIGA 2VF1A 5LMUE 5F3WA 4L8NA 1WXRA 4X66E 1IBKE 2JVAA 1WHQA 4LF8E 2DIXA 1RC5A 4DUZE 5AASA 2NUEA 2YZTA 1XMQE 4B3RE 4GKKE 2FFLA 4AQYE 2N3GA 3RMPA 3H09A 4KHPE 5FLXC 4LF9E 1DI2A 5AE2A 1WHNA 1XMOE 2RS6A 2WZOA 3ADJA 5AE1A 2M7QA 4JI5E 5LMNE 1HNWE 3MSWA 4BC9A 2V85A 1X49A 4B3TE 2LUQA 3F6GA 4JI1E 5A2QC 4M0VA 4X64E 2E1MA 4JI2E 4WYQB 3VK6A 4DV5E 1HR0E 4BCAA 4YHHE 3JTZA 3LLHA 2MDRA 3AUZA 1YYOA 2RTXA 1HNXE 2V83A 4OX9E 1ZBQA 3HQ1A 4DV1E 1IBLE 4LF5E 4BBYA 2ZM6E 4JI6E 5CFFE 2UUBE 3P1XA 4F9BB 4WFTA 3J81C 1FJGE 4X8WA 4JV5E 1YYWA 2K4VA 3O2RB 1YYKA 2LTSA 3IWDA 2A11A 2L3JA 1YZ9A 2H36X 2B7TA 4BS9A 2B7VA 4WPYA 4WSPA 4X62E 4DR5E 2DMYA 1T4OA 2L33A 2VQEE 3HTXA 3J7Yp 2L2MA 4TUGA 2L2KB 2DSYA 3LMLA 4DR4E 4DUYE 4GEQB 4DKKA 4JYAE 4TUIA 4LU9A 2JY9A 4K0KE 2L2NA 2YT4A 4DV7E 3ADGA 2JOBA 4JI4E 2NA2A 4I8OA 3N3WA 3J80C 4GKJE 2V8QB 2F4VE 2VE7C 2UUCE 3T1HE 2NUFA 3RV1A 2RSMA 2V88A 2B3TB 2HHHE 4DR2E 3JU0A 5AE3A 2CPNA 2DB2A 2EZ6A 1PKPA 2L6MA 4LF6E 1X47A 2V87A 3OTOE 2LTRA 4B3SE 3HXLA 1N33E 2QVWA 2JWOA 4DMIA 1JFZA 4LF7E 3ZOQB 1IBME 4F54A 4B3ME 4JI3E 1XNQE 4DV0E 1SR9A 2LRSA 5IT9C 4F9CB 4NXME 4NXNE 3VYXA 2UXDE 4LF4E 1J26A 4YY3E 1RC7A 1DQ3A 2KONA 2RS7A 1UHZA 2EWLA 4DV6E 2LJHA 2E5LE 1T4NA 1T4LB 3ADIA 4P7DA 3C4BA 1X48A 4R03A 1J5EE 3IWCA 1I94E 1EKZA 1O0WA 2V89A 2KOUA 3DJWA 2EB1A 3IWBA 4M30A 2F8BA 2V86A 3F6HA 2L3CA 2MC6A 1I4SA 1ZBTA 3KWRA 4LFBE 5T6JA 5DNYA 4DV3E 2JOXA 3ADLA 2FTXB 1GQEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LUP B;  1RQ0 A;  1N32 E;  4M2Z A;  4JI8 E;  1UIL A;  4DV2 E;  2N3H A;  4JI0 E;  4OOG C;  2UXB E;  2LBS B;  2IHR 1;  5IWA E;  3T1Y E;  4DR7 E;  3VYY A;  1XNR E;  1N36 E;  1QU6 A;  3RV0 A;  2VQF E;  2UU9 E;  4LFC E;  4DR1 E;  2KHX A;  4JI7 E;  3O2R A;  1FKA E;  4DV4 E;  4DR3 E;  3C4T A;  2GSL A;  2UXC E;  4LFA E;  2UUA E;  5BR8 E;  4OUN A;  2NUG A;  1HNZ E;  4OX9 E;  1STU A;  1N34 E;  4X65 E;  1IBK E;  5LMU E;  4LF8 E;  4X66 E;  2JVA A;  1WHQ A;  2DIX A;  1RC5 A;  4DUZ E;  4B3R E;  2NUE A;  1XMQ E;  4GKK E;  2FFL A;  4AQY E;  2N3G A;  4KHP E;  1DI2 A;  4LF9 E;  1XMO E;  1WHN A;  2RS6 A;  3ADJ A;  4JI5 E;  5LMN E;  1HNW E;  1X49 A;  4B3T E;  2LUQ A;  4JI1 E;  4X64 E;  4JI2 E;  4WYQ B;  4DV5 E;  1HR0 E;  4YHH E;  3LLH A;  2MDR A;  1YYO A;  2RTX A;  1HNX E;  4DV1 E;  1IBL E;  4LF5 E;  4JI6 E;  2ZM6 E;  5CFF E;  2UUB E;  3P1X A;  4WFT A;  1FJG E;  4X8W A;  4JV5 E;  1YYW A;  3O2R B;  1YYK A;  2LTS A;  2A11 A;  2L3J A;  1YZ9 A;  2B7T A;  2B7V A;  4X62 E;  4DR5 E;  2DMY A;  1T4O A;  2L33 A;  2VQE E;  3HTX A;  3J7Y p;  2L2M A;  2L2K B;  4DR4 E;  4DUY E;  4DKK A;  4JYA E;  2JY9 A;  4K0K E;  2L2N A;  2YT4 A;  4DV7 E;  3ADG A;  4JI4 E;  2NA2 A;  3N3W A;  4GKJ E;  2F4V E;  2UUC E;  3T1H E;  2NUF A;  3RV1 A;  2RSM A;  2B3T B;  2HHH E;  4DR2 E;  2CPN A;  2DB2 A;  2EZ6 A;  1PKP A;  4LF6 E;  1X47 A;  3OTO E;  2LTR A;  4B3S E;  1N33 E;  2QVW A;  1JFZ A;  4LF7 E;  1IBM E;  4B3M E;  4JI3 E;  1XNQ E;  4DV0 E;  2LRS A;  4NXM E;  4NXN E;  3VYX A;  2UXD E;  4LF4 E;  1J26 A;  4YY3 E;  1RC7 A;  2RS7 A;  4DR6 E;  1UHZ A;  4DV6 E;  2E5L E;  2LJH A;  1T4N A;  1T4L B;  3ADI A;  3C4B A;  1X48 A;  1J5E E;  1I94 E;  1EKZ A;  1O0W A;  2EB1 A;  4M30 A;  2L3C A;  1I4S A;  1ZBT A;  4LFB E;  4DV3 E;  3ADL A;  1U61 A;  1GQE A; 
#chains in the Genus database with same CATH topology
 5LL6 R;  3DF6 A;  5ADZ A;  2JXP A;  2EM2 A;  2CTD A;  2LBS B;  3THO B;  1TN9 A;  1F2I G;  4DR7 E;  2EML A;  3VYY A;  4J8Z A;  1LLM C;  1AH5 A;  2VQF E;  2M4I A;  2KHX A;  3HPS A;  3O2R A;  3C4T A;  3EPJ A;  2GSL A;  2ODR C;  4KZS A;  2LCE A;  2G7H A;  2L8T A;  2EMH A;  2MC5 A;  5BR8 E;  2JR1 A;  1HNZ E;  2NAB A;  5KL3 A;  1IBK E;  5LMU E;  2VF1 A;  5F3W A;  4LF8 E;  4L8N A;  4FK5 C;  2JVA A;  2EOM A;  4O43 A;  4AQY E;  4KHP E;  5FLX C;  2EM8 A;  2WZO A;  3ADJ A;  2EOO A;  2WCC 3;  1HNW E;  5KL2 A;  1RMD A;  1X3C A;  4JI1 E;  2RQL A;  3EPH A;  4WYQ B;  2GLI A;  4BHB A;  1EH7 A;  2RTX A;  2EOR A;  1ZBQ A;  2JYA A;  4WX9 A;  1A1K A;  2RSI A;  1IBL E;  2DGC A;  4JI6 E;  2M9A A;  5CFF E;  3BID A;  3P1X A;  2YRH A;  4WFT A;  2LT7 A;  1FJG E;  4X8W A;  1L4S A;  2LTS A;  2YTO A;  2B7T A;  4KWY A;  3QG5 C;  4DR5 E;  2L33 A;  1T4O A;  2HGH A;  3J7Y p;  2L2M A;  4TUG A;  3LML A;  4DR4 E;  1IQO A;  2YTJ A;  4JYA E;  1YSA C;  2EP3 A;  4I8O A;  2EPU A;  3T1H E;  3THN A;  2WBT A;  4RH8 A;  2B3T B;  1A1G A;  4M9V C;  4ZYH A;  3JU0 A;  2CPN A;  2EZ6 A;  2YTF A;  3OTO E;  3HXL A;  2JWO A;  2EMK A;  1JFZ A;  2BBG A;  2EE8 A;  3ZOQ B;  1YPN A;  4LF7 E;  3KZZ A;  4JI3 E;  1XNQ E;  2LRS A;  3VYX A;  4LF4 E;  2EPR A;  4DR6 E;  2RS7 A;  2E5L E;  1J5E E;  2EL5 A;  2R1F A;  2EOJ A;  4BHC A;  2V89 A;  4RHB B;  4R2P A;  2V86 A;  5DNY A;  4DV3 E;  3ADL A;  1NCS A;  1RQ0 A;  2EN1 A;  5KL7 A;  4Q28 A;  2N3H A;  2UXB E;  2B9D A;  2MKD A;  3MHH C;  3T1Y E;  2DMI A;  1XNR E;  2DLK A;  3BBG A;  2YRK A;  4BC7 A;  5A6B A;  2EOI A;  2UU9 E;  3OML A;  1BBO A;  2K7I A;  1MEY C;  2EQ0 A;  2EOS A;  5KL5 A;  4LFC E;  4DR1 E;  3L00 A;  1QNT A;  2FGG A;  2UXC E;  2ENH A;  2D9H A;  3JAM C;  2EOQ A;  1ZTD A;  2YWQ A;  1GZ6 A;  1YFH A;  4P78 A;  4X65 E;  2FV4 B;  2J7J A;  2YU5 A;  3FIG A;  1WXR A;  1UN6 B;  2EMG A;  1RC5 A;  1PJT A;  5AAS A;  2EOE A;  4DUZ E;  1A1J A;  5KL4 A;  2EPM X;  3RMP A;  1XMO E;  2LV2 A;  1EH8 A;  2N8X A;  4O24 A;  2EPL X;  3MSW A;  4BC9 A;  4B3T E;  2EM4 A;  4JI2 E;  3VK6 A;  4ZYD A;  4BCA A;  3LLH A;  3AUZ A;  1YYO A;  3C6M A;  1T39 A;  2EOX A;  2ZM6 E;  2EM3 A;  2JP9 A;  4F9B B;  3J81 C;  1G2D C;  2K4V A;  1YYK A;  2L3J A;  2I9I A;  2H36 X;  1GTK A;  4WSP A;  3HTX A;  1PJS A;  4F6N A;  2EN7 A;  1PDA A;  3UK3 C;  2EL6 A;  1JK1 A;  4R2R A;  4DKK A;  1KYQ A;  2Q8U A;  4LU9 A;  4K0K E;  5A6B D;  3ADG A;  2JOB A;  2NA2 A;  1DGC A;  4X9J A;  4GKJ E;  2V8Q B;  4R2D A;  2VE7 C;  2NUF A;  2CT1 A;  2EMZ A;  2HHH E;  2ADR A;  4DR2 E;  5TSE A;  5AE3 A;  1PKP A;  2L6M A;  1X5W A;  1X47 A;  4LF6 E;  4F2J C;  2QVW A;  1B69 A;  2EM9 A;  2EN4 A;  4MLV A;  1SR9 A;  4ZYE A;  4WXC A;  1J26 A;  1KJK A;  1RC7 A;  1DQ3 A;  2EPP A;  2KON A;  2LJH A;  2ELZ A;  1T4L B;  3ADI A;  1YUJ A;  4R03 A;  1I94 E;  3IWC A;  2YSP A;  1O0W A;  5IV8 B;  2KOU A;  3IWB A;  4M30 A;  3F6H A;  2L3C A;  1I4S A;  1Z1B A;  4LFB E;  5T6J A;  2LUP B;  3J7A G;  3K6Q A;  1X6F A;  4M2Z A;  4JI8 E;  4DV2 E;  2LVH A;  2YU8 A;  2IHR 1;  1N3G A;  4R2E A;  4F9A B;  4L5N C;  4R8O A;  1QU6 A;  3RV0 A;  4BMJ A;  4WXD A;  4JI7 E;  1FKA E;  4DV4 E;  2MKN A;  4WSG A;  3AV0 A;  3EPK A;  2R76 A;  4LFA E;  1WJP A;  2RPC A;  2EPA A;  2MDG A;  1ZU1 A;  3EQ1 A;  3M99 B;  4OUN A;  2NUG A;  4R2C A;  1G2F C;  1STU A;  2M1S A;  1YUI A;  4OX9 E;  1JK2 A;  2EPC A;  1WHQ A;  2NUE A;  2YZT A;  1NEI A;  1XMQ E;  1A1H A;  4GKK E;  3H09 A;  4LF9 E;  1ZR9 A;  2RS6 A;  1X6E A;  5AE1 A;  4JI5 E;  1EH6 A;  2EMA A;  5LMN E;  1A1L A;  2I13 A;  2V85 A;  4IJD A;  5KL6 A;  3F6G A;  4M0V A;  2HJJ A;  2E1M A;  4DV5 E;  3C6K A;  1HR0 E;  2PRT A;  4MLQ A;  2V83 A;  1ZAA C;  1TF6 A;  2EM7 A;  1BBG A;  2EMF A;  5A6J A;  4R2Q A;  2ELY A;  3IWD A;  1YZ9 A;  2YTP A;  4BS9 A;  4GZN C;  2EN8 A;  2ENC A;  2B7V A;  4WPY A;  4X62 E;  2DMY A;  2VQE E;  2EL4 A;  2DLQ A;  2EOF A;  2L2K B;  2DSY A;  1MGT A;  2EMI A;  4GEQ B;  5AC4 A;  5IXM B;  3ECR A;  2YT4 A;  2EPN A;  4JI4 E;  2E72 A;  2YTD A;  2WBU A;  2F4V E;  3RV1 A;  2RSM A;  3VHT B;  2YTE A;  4HEI A;  2GHF A;  2V87 A;  4B3S E;  1N33 E;  2ENA A;  1IBM E;  4DV0 E;  2EPO A;  4F9C B;  4NXM E;  2UXD E;  4YY3 E;  4DV6 E;  2YTN A;  4P7D A;  4Q35 B;  4NHR A;  1A1I A;  4IS1 C;  2F8B A;  2EN3 A;  3KWR A;  2EN2 A;  1U61 A;  2EOZ A;  4O5G A;  1GQE A;  1P47 A;  1N32 E;  4O4K A;  1UIL A;  2EMB A;  2EPX A;  1BB8 A;  4JI0 E;  4LTY A;  4OOG C;  2DRP A;  2BB8 A;  5IWA E;  1IQS A;  2EM5 A;  1N36 E;  2LJU A;  2ODR D;  4R2A A;  2LMZ A;  4DR3 E;  2LE2 A;  2HC5 A;  2L92 A;  2EOY A;  2EPK X;  2UUA E;  3HPZ A;  1N34 E;  4X66 E;  2DIX A;  2EOH A;  4B3R E;  1SFE A;  2FFL A;  2N3G A;  1DI2 A;  1IMU A;  1TF3 A;  5AE2 A;  1WHN A;  1A1F A;  2M7Q A;  1X49 A;  3BGH A;  2EMC A;  2GPI A;  2LUQ A;  5A2Q C;  1PJQ A;  2EQ3 A;  2YTI A;  4X64 E;  2EMY A;  4YHH E;  3JTZ A;  2MDR A;  1HNX E;  2EJ4 A;  3HQ1 A;  4DV1 E;  2EN6 A;  5AC5 A;  4LF5 E;  4BBY A;  4R2S A;  2YTG A;  2UUB E;  5A6A A;  4JV5 E;  1YYW A;  3O2R B;  2EMX A;  2EPZ A;  2EM0 A;  1AAY A;  2A11 A;  1X6H A;  3BF2 A;  1UBD C;  3MHS C;  2EQ1 A;  2EMW A;  2A25 A;  4DUY E;  4TUI A;  2JY9 A;  2JPA A;  2L2N A;  4DV7 E;  3TQM A;  3N3W A;  4NZV A;  3J80 C;  1WRJ A;  2CSH A;  2YPN A;  2UUC E;  2V88 A;  3KZY A;  4ZYG A;  2DB2 A;  2LTR A;  2YTQ A;  4DMI A;  5LLQ A;  2LO3 A;  4N4R B;  4F54 A;  4B3M E;  3EPL A;  5IT9 C;  2WBS A;  4F6M A;  2YRM A;  4NXN E;  1T38 A;  5A6K A;  1UHZ A;  2EWL A;  1T4N A;  2VRD A;  3C4B A;  1X48 A;  1EKZ A;  3DJW A;  2EB1 A;  5A69 A;  2EM6 A;  2MC6 A;  1ZBT A;  2YSO A;  2JOX A;  2FTX B;  4HTG A; 
#chains in the Genus database with same CATH homology
 2LUP B;  1RQ0 A;  5LL6 R;  1N32 E;  3J7A G;  3DF6 A;  3K6Q A;  5ADZ A;  4M2Z A;  4JI8 E;  1UIL A;  4DV2 E;  4Q28 A;  2N3H A;  4JI0 E;  4LTY A;  4OOG C;  2UXB E;  2LBS B;  2IHR 1;  2B9D A;  4F9A B;  5IWA E;  3T1Y E;  3VYY A;  4L5N C;  4DR7 E;  1XNR E;  4R8O A;  4J8Z A;  4BC7 A;  1N36 E;  1QU6 A;  3RV0 A;  4BMJ A;  2VQF E;  1U61 A;  2ODR D;  2UU9 E;  3OML A;  4LFC E;  2M4I A;  4DR1 E;  4DR6 E;  2KHX A;  3HPS A;  4JI7 E;  3O2R A;  2LMZ A;  4DV4 E;  2LE2 A;  3C4T A;  4DR3 E;  2FGG A;  2GSL A;  2ODR C;  3AV0 A;  1FKA E;  2UXC E;  4KZS A;  4LFA E;  2L92 A;  2G7H A;  2L8T A;  3JAM C;  2UUA E;  2MC5 A;  5BR8 E;  4OUN A;  2NUG A;  2JR1 A;  3HPZ A;  1STU A;  2M1S A;  1N34 E;  1GZ6 A;  1HNZ E;  4P78 A;  4X65 E;  2FV4 B;  3FIG A;  2VF1 A;  5LMU E;  5F3W A;  4L8N A;  1WXR A;  4X66 E;  1IBK E;  2JVA A;  1WHQ A;  4LF8 E;  2DIX A;  1RC5 A;  4DUZ E;  5AAS A;  2NUE A;  2YZT A;  1XMQ E;  4B3R E;  4GKK E;  2FFL A;  4AQY E;  2N3G A;  3RMP A;  3H09 A;  4KHP E;  5FLX C;  4LF9 E;  1DI2 A;  5AE2 A;  1WHN A;  1XMO E;  2RS6 A;  2WZO A;  3ADJ A;  5AE1 A;  2M7Q A;  4JI5 E;  5LMN E;  1HNW E;  3MSW A;  4BC9 A;  2V85 A;  1X49 A;  4B3T E;  2LUQ A;  3F6G A;  4JI1 E;  5A2Q C;  4M0V A;  4X64 E;  2E1M A;  4JI2 E;  4WYQ B;  3VK6 A;  4DV5 E;  1HR0 E;  4BCA A;  4YHH E;  3JTZ A;  3LLH A;  2MDR A;  3AUZ A;  1YYO A;  2RTX A;  1HNX E;  2V83 A;  4OX9 E;  1ZBQ A;  3HQ1 A;  4DV1 E;  1IBL E;  4LF5 E;  4BBY A;  2ZM6 E;  4JI6 E;  5CFF E;  2UUB E;  3P1X A;  4F9B B;  4WFT A;  3J81 C;  1FJG E;  4X8W A;  4JV5 E;  1YYW A;  2K4V A;  3O2R B;  1YYK A;  2LTS A;  3IWD A;  2A11 A;  2L3J A;  1YZ9 A;  2H36 X;  2B7T A;  4BS9 A;  2B7V A;  4WPY A;  4WSP A;  4X62 E;  4DR5 E;  2DMY A;  1T4O A;  2L33 A;  2VQE E;  3HTX A;  3J7Y p;  2L2M A;  4TUG A;  2L2K B;  2DSY A;  3LML A;  4DR4 E;  4DUY E;  4GEQ B;  4DKK A;  4JYA E;  4TUI A;  4LU9 A;  2JY9 A;  4K0K E;  2L2N A;  2YT4 A;  4DV7 E;  3ADG A;  2JOB A;  4JI4 E;  2NA2 A;  4I8O A;  3N3W A;  3J80 C;  4GKJ E;  2V8Q B;  2F4V E;  2VE7 C;  2UUC E;  3T1H E;  2NUF A;  3RV1 A;  2RSM A;  2V88 A;  2B3T B;  2HHH E;  4DR2 E;  3JU0 A;  5AE3 A;  2CPN A;  2DB2 A;  2EZ6 A;  1PKP A;  2L6M A;  4LF6 E;  1X47 A;  2V87 A;  3OTO E;  2LTR A;  4B3S E;  3HXL A;  1N33 E;  2QVW A;  2JWO A;  4DMI A;  1JFZ A;  4LF7 E;  3ZOQ B;  1IBM E;  4F54 A;  4B3M E;  4JI3 E;  1XNQ E;  4DV0 E;  1SR9 A;  2LRS A;  5IT9 C;  4F9C B;  4NXM E;  4NXN E;  3VYX A;  2UXD E;  4LF4 E;  1J26 A;  4YY3 E;  1RC7 A;  1DQ3 A;  2KON A;  2RS7 A;  1UHZ A;  2EWL A;  4DV6 E;  2LJH A;  2E5L E;  1T4N A;  1T4L B;  3ADI A;  4P7D A;  3C4B A;  1X48 A;  4R03 A;  1J5E E;  3IWC A;  1I94 E;  1EKZ A;  1O0W A;  2V89 A;  2KOU A;  3DJW A;  2EB1 A;  3IWB A;  4M30 A;  2F8B A;  2V86 A;  3F6H A;  2L3C A;  2MC6 A;  1I4S A;  1ZBT A;  3KWR A;  4LFB E;  5T6J A;  5DNY A;  4DV3 E;  2JOX A;  3ADL A;  2FTX B;  1GQE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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