1IOFA

X-ray crystalline structures of pyrrolidone carboxyl peptidase from a hyperthermophile, pyrococcus furiosus, and its cys-free mutant
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
208
structure length
208
Chain Sequence
MKVLVTGFEPFGGEKINPTERIAKDLDGIKIGDAQVFGRVLPVVFGKAKEVLEKTLEEIKPDIAIHVGLAPGRSAISIERIAVNAIDARIPDNEGKKIEDEPIVPGAPTAYFSTLPIKKIMKKLHERGIPAYISNSAGLYLCNYVMYLSLHHSATKGYPKMSGFIHVPYIPEQIIDKIGKGQVPPSMCYEMELEAVKVAIEVALEELL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray crystalline structures of pyrrolidone carboxyl peptidase from a hyperthermophile, Pyrococcus furiosus, and its cys-free mutant
pubmed rcsb
molecule tags Hydrolase
source organism Pyrococcus furiosus
molecule keywords PYRROLIDONE CARBOXYL PEPTIDASE
total genus 69
structure length 208
sequence length 208
chains with identical sequence B, C, D
ec nomenclature ec 3.4.19.3: Pyroglutamyl-peptidase I.
pdb deposition date 2001-03-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01470 Peptidase_C15 Pyroglutamyl peptidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.630.20 Alpha Beta 3-Layer(aba) Sandwich Aminopeptidase Peptidase C15, pyroglutamyl peptidase I-like 1iofA00
2EBJA 3RNZA 3LACA 3GIUA 1Z8XA 2EO8A 2DF5A 1X12A 4HPSA 1A2ZA 1Z8WA 1IU8A 3RO0A 4GXHA 1AUGA 1IOIA 1IOFA 1Z8TA 1X10A
chains in the Genus database with same CATH superfamily
3F8KA 4A95A 4ORFA 3D68A 2X7BA 5KTDA 4R8FA 2Q4YA 2Z3LA 3FX6A 3GIUA 3H8GA 4W9YA 1PUAA 3SI0A 3K9UA 4RN7A 1I21A 1TKJA 2Q51A 2WYRA 1CJWA 4UA3A 4UCNA 3D67A 2JDDA 3D2PA 4KOVA 1TKHA 4B6ZA 2GE3A 4UBRA 3CXSA 3FYNA 4H2KA 1R3NA 3LD2A 3PB4X 3PBBA 4CGMA 1Q2CA 3PB8X 4R87A 1KUVA 2VZZA 3ISZA 3LMSA 4UFXA 5HVFA 2NYQA 3B7IA 3F0AA 3NH5A 3PB6X 1M1DA 2Q4ZA 2B58A 4MCQA 3NE8A 3GUXA 5HH1A 4UFWA 1LRZA 1ZLIA 2DEAA 3BI0A 4U5YA 3IWGA 2ZOGA 1B87A 5EMIA 3GY9A 4A30A 4YRHA 4ZGYB 3PFEA 3OWCA 2Q4VA 3CXQA 3QAHA 3FF3A 4C2XA 1FNOA 2YGWA 3SJEA 5JQ4A 4QB9A 4PXDA 1IY7A 3GLJA 2ZW4A 4ZX8A 4LUAA 2POKA 2PJ3A 4UCPA 3TO7A 4KVME 3I3GA 3ZZIA 3NH8A 4PXCA 3BXMA 4C7IA 3I1UA 3QAYA 1KUYA 1XJOA 2RFHA 4JXRA 5G22A 4B14A 5J1QA 3KL9A 3B35A 4C7HA 3R1KA 3BJ8A 1BPMA 4EFDA 1KUXA 4DUKA 1YX0A 2OB0A 4A32A 4ONWA 3PP9A 5EC4A 3T9YA 2PJ5A 2BO9A 2G0BA 1UFHA 2G9DA 4OC4A 4AB7A 5A28A 1P0HA 3S6FA 1NSAA 2Q43A 3UY5A 3PB9X 4KLVA 4MFPA 3B3WA 1YR0A 2R8VA 3DR6A 2FCKA 4MMOA 4WWVA 3WC6A 3P2HA 4MY0A 2F7VA 3DLJA 2DF5A 2JEWA 1MJ9A 3BHXA 5G1ZA 3L2NA 4CGPA 4UIAA 3VWEA 1IGBA 3S6GA 4E8OA 4JD6A 1TIQA 1YREA 3PRTA 1YSJA 3FEEA 3PZJA 4OLLA 4PK3A 2FE7A 3P2FA 4KUAA 3KGQA 1S7KA 2IQ6A 1UWYA 3D66A 3IC1A 3NE7A 2FL4A 3KASA 3K9TA 1AYEA 4KOXA 5LYDA 3N7ZA 3WC7A 2IMOA 4MJ8A 3SJFA 2YNDA 3CPAA 4ZY0A 3R9FA 1XEBA 5AG7A 2V8DA 4YWYA 3ZJ0A 3KQZA 3NFZA 2D4PA 4PV6A 4ZYQA 1ELLP 4FD4A 4BBHA 5K8NA 2BSWA 1CPXA 4NSQA 3NA6A 5KTAA 1IU8A 4UWJA 4E2AA 4KSFA 1U6MA 1Z2LA 3PGPA 2ZEPA 3S9NA 2B4DA 1QQ9A 4A2ZA 4F6AA 1BPNA 2EK8A 5JM6A 5K8MA 3V8IA 3S6KA 5EBVA 2C6CA 1MK4A 2NMTA 2HV2A 3SI1A 5G20A 2ZEEA 1X10A 2ODFA 2Q7BA 4CRZB 1IB1E 4ZY2A 2PR8A 3IO1A 2NSMA 2O28A 3SJGA 3R95A 1Z9UA 2RB7A 1M4LA 4P44A 3TOBA 4OIDA 2PJ1A 2ZW7A 4CGNA 5IV0A 2PJ7A 3F5BA 4YU9A 4NF1A 1GHEA 1K4JA 3JRUA 3NH4A 4UWIA 1S3ZA 5CNPA 2DPSA 2ANPA 4YGOA 3B3CA 3B3VA 4GXHA 2I79A 4A38A 4KVOE 2B5GB 3CZXA 1Y7EA 4OMEA 3W6XA 4XPDB 2BL1A 2J9AA 3H8EA 1Z4EA 4AG7A 1BOBA 3PBEA 4P4BA 2CIJA 1R57A 4B5PB 2FXFA 4JZ0A 2PC1A 2CNSA 4UEZA 1NSLA 2ZPAA 4R57A 1CG2A 1Y0RA 1Y9KA 3B2YA 3KHZA 2PJ9A 2HC9A 2D4OA 5H86A 1V0CA 4PK2A 1ARMA 4NGRA 3FJUA 4MHNA 2CF4A 2J8MA 4QC6A 1M4GA 4JYWA 4R9MA 1YLEA 4JLYA 2FS5A 3FNCA 4NXYA 3S9LA 1YW6A 4HNYB 3SXOA 1RTQA 2OZUA 3IFEA 5AGEA 4ZI6A 4RS2A 2CY2A 1VHEA 1B6BA 4U9YA 4Q7AA 4M6IA 2BEIA 4JJXA 2A4NA 2JBKA 3TO9A 5THWA 3D2MA 1L0CA 1S7LA 2OR4A 2O4HA 3S6HA 1LFWA 2AFZA 3QNVA 2FVGA 1HDUA 3FBUA 3G8WA 3D7GA 3IU1A 5D8NA 1Z5RA 4FAIA 1JQGA 2HUZA 3RAMA 1OZPA 2AJ6A 3GYAA 1CPSA 5LYFA 2VL1A 4L89A 4X3RA 4II9A 1XFOA 4PSXA 2PVWA 5J8CA 2VEZA 4OP4A 3CDXA 1F2PA 1ZO0A 4NGSA 5LRJA 1QMUA 1IICA 2Z3NA 2OU2A 3V7ZA 5K8OA 4C68A 1AUGA 2ZEGA 3TFYA 4OKOA 3TT2A 1YK3A 4A31A 2R1IA 3FMCA 3D3SA 2WPWA 2AFMA 2GLJA 1S5KA 2Z3MA 4UCMA 2XEGA 4NGQA 1Z8LA 3DR8A 3E0KA 5C88A 5FVJA 1SQHA 4Q38A 3D4UA 3TC8A 5DS0A 3FXTA 3W91A 2CTCA 4R6TA 4KSAA 2QECA 4C2ZA 1PU9A 2ARHA 4H6UA 1QSRA 4A94A 2FSRA 2IJZA 4XNHB 1XBUA 5F48A 3FIXA 4P4JA 8CPAA 4NGPA 1VGYA 2VXKA 4MFZA 1LAPA 1XE4A 4J3GA 1XIXA 4XPKA 5AG6A 3TOAA 5KTCA 4OAEA 2G3TA 3MRUA 3D8PA 4EWTA 2IL4A 2C1CA 2REFA 5DWMA 4MCPA 4I49A 2PJ6A 4KORA 2JBJA 2PJAA 4MXUA 5H84A 1ARLA 2ZW5A 4C2YA 5D29A 2JEVA 4GS4A 4PPZA 4X8IA 3R96A 3TO6A 3TTHA 4NJQA 2PDOA 4B12A 1ON0A 4LX9A 4F9VA 2R98A 4PXBA 5E96A 2EBJA 2PIZA 4P10A 1S7NA 4UEFA 2O53A 4CYOA 2CXAA 3LACA 4P45A 4BD9A 4ZBGA 4IAVA 1YW4A 2DXQA 2V8VA 3RBUA 3MGDA 3KI9A 4CRYB 1H8LA 1I12A 2K5TA 2C6GA 2PJCA 2V8HA 3GKRA 3EY5A 3GB0A 1S60A 3CT9A 3KHXA 4AVBA 1AMPA 3JVNA 4Q36A 1XF8A 1HDQA 4AVCA 4CGLA 1CP6A 1NE9A 1IOIA 5F47A 3IWWA 4B13A 4LQGA 4QVTA 4MI4A 1YQEA 1LAMA 4P4IA 2PR1A 3FB3A 1ZG7A 2PJ8A 3IEHA 3TX8A 3SJXA 4FWUA 1XMTA 4P4DA 2BOAA 4NJRA 4TWEA 1DTDA 4OC5A 5CBMA 4NGMA 2EUIA 4KSIA 1ELMP 3BLNA 5LRKA 1Q2DA 3VWDA 3TE4A 3B8GA 3I9SA 4P4EA 3DSBA 5GCNA 4HPSA 2YNEA 4KOSA 4KS9A 3WABA 2PIYA 2KCWA 1Z8WA 1Y9WA 2PJBA 2G3AA 2I00A 2XEIA 5LYIA 2PRQA 4NEXA 3EFAA 2ZEDA 2F5IA 3R9EA 3T90A 3KKWA 4XPDC 4RI1A 2AFUA 3PEIA 3EO4A 4WJBA 4MCSA 3D7FA 4CYNA 3ISXA 1I1DA 4DNCA 4M3SA 5IB0A 1MJAA 4CGOA 4E0AA 4KVXA 3DGVA 3BJ7A 3JUWA 2B4BA 1P4NA 4HNXB 2VZYA 1YMEA 2ZW6A 3IU2A 2WUUA 4AG9A 2AFOA 4IHMA 4KOYA 4CS0B 4M6GA 4EVYA 5BWAB 5HMNA 5HVGA 4ZY1A 1EE3P 2QYVA 1CP7A 4X2TA 1FT7A 4QUSA 4R76A 4MFJA 1VKCA 4B5OA 3SHPA 2H5MA 2YNCC 4ONUA 4JWPA 2AFSA 4P6YA 4KUBA 2GFQA 4R3LA 2OZHA 3H8FA 1M4IA 4ZX9A 3DNSA 3G3SA 3KR5A 1PYTB 2WZNA 3LWUA 2Z11A 1QSNA 2PSWA 2Q44A 3WR7A 4H6ZA 1TF8A 4KOWA 4A33A 4L8AA 4B10A 4IUSA 4LQ6A 4MHZA 5I4MA 2XEFA 7CPAA 2JLMA 1TXRA 2Z10A 3H5ZA 4MHYA 2Z3KA 2I3CA 1Z8XA 2ZELA 4NFRA 2AE6A 4BMHA 4KLWA 4F0XA 2PJ0A 1Q7LA 4Y49C 3WT4A 4BINA 4DJLA 2P6FA 4Y49B 1X12A 2RC4A 3TCVA 4UFVA 1IYKA 4FD6A 2Z0ZA 3EC4A 2PRBA 4HKFA 1KWMA 1RXTA 3RO0A 3H4QA 3KR4A 4HNWB 2GU2A 3VH9A 2ZENA 2PE3A 3FEDA 4DYOA 5F49A 4F8ZA 3V38A 5J8FA 1Q2YA 4NGTA 2OZGA 2J8RA 1GYTA 1LANA 2QIRA 2ZXVA 2ZEOA 1OBRA 3BI1A 2P6EA 2ZEHA 2Z3PA 2ZEFA 3A9LA 1JWQA 3IJ3A 1M4DA 4A37A 5G21A 2EO8A 3FRMA 4XNHC 2CNTA 3C26A 2Y0MA 2PJ2A 5A27A 2B3VA 2REEA 3SI2A 2FIWA 4OC3A 1FY7A 2P0WA 2QMLA 3K2KA 2Q7SA 3EXNA 2C27A 2QJ8A 3FECA 2GANA 1LOKA 1WK4A 1VIXA 4OC0A 1CX8A 4CAWA 4B11A 1DE4C 2PJ4A 2PQ8A 3D7HA 1VHOA 5JH9A 2FT0A 2F8HA 5HVHA 2BUEA 3HUVA 5LRGA 1Y7RA 1S7FA 2PVVA 4UIBA 2VI7A 5F46A 2VQYA 4EMEA 2EK9A 4CYQA 4CYPA 4CAFA 1Z8TA 1YGHA 4M6HA 3RZAA 3CXPA 4OC1A 3T8WA 1TKFA 2QVPA 4IK2A 2V77A 3IWEA 3RNZA 3MN8A 1TF9A 1RO5A 1QSMA 2JDCA 4MFKA 4QBJA 1XMBA 2ATRA 2GLFA 4CAEA 2CTBA 5ISVA 1LCPA 4Z65A 3B3SA 1VHSA 2PCUA 3CPXA 2HQYA 2WPXA 1XOVA 1F57A 3D7DA 3IGRA 4A39A 1NMTA 2HB6A 5AG4A 4OC2A 1QSOA 3QB8A 3PB7X 4FD7A 2V8GA 4KZTA 4OADA 4AXVA 2P6GA 2B5GA 1BAVA 1YLOA 3R9GA 4YFJA 1PCAA 4PSWA 4NGNA 5F09A 1F2OA 1HEEA 2BCOA 3W6SA 4B5PA 5JPHA 2VBQA 5CPAA 4F0YA 4UEEA 1XRYA 4PXEA 3RYOA 6CPAA 2C6PA 4G1PA 3FVLA 1ZLHA 2ABZA 1YVKA 5K8PA 4U9ZA 5I0CA 3N5FA 4FD5A 2J8NA 3HLPA 4MCRA 4NCZA 4X5KA 1A2ZA 3S9MA 1ZG9A 2ZEMA 1KZFA 3VARA 2AFWA 5DWNA 2GREA 4F9UA 2B3UA 5HXDA 4TNUA 2OOTA 1IIDA 2YNCA 1IOFA 2OH1A 2ZOFA 4OIWA 4MFLA 5ELYA 4KOUA 5AG5A 5IB9A 1BLLE 1IYLA 2Q04A 4IF5A 4PQAA 4CAXA 5LYLA 4M85A 2Q0YA 3DDDA 3VATA 1ZG8A 4MFQA 3FH4A 3WC5A 1Z4RA 1M44A 5IX3A 1CM0A 1J4JA 4MHDA 4RUHA 1BO4A 4CPAA 4KOTA 1CBXA 3KZWA 2Z3OA 2R7HA 4CAVA 2EWBA 5JGFA 3PFOA 2EVNA 4P4FA 2XEJA 4AVAA 4K3NA 1MJBA 4GM5A 4R7MA 2FIAA 2AFXA 3JTKA 4XPLA 2DPTA 4R3KA 3KQXA 1Y0YA 3B3TA 2B4DB 3LODA 4H89A 2CNMA 4MRIA 3SXNA 4FBEA 5C82A 2WSAA 1YVOA 4MBUA 4JXQA 4K30A 2GIVA 1WWZA 4FUUA 4MHPA 3IIBA 4O23A 4MY3A 1N71A 1QSTA 4UF4A 1R43A
chains in the Genus database with same CATH topology
2EBJA 3RNZA 3LACA 3GIUA 1Z8XA 2EO8A 2DF5A 1X12A 4HPSA 1A2ZA 1Z8WA 1IU8A 3RO0A 4GXHA 1AUGA 1IOIA 1IOFA 1Z8TA 1X10A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EBJ A;  3RNZ A;  3LAC A;  3GIU A;  1Z8X A;  2EO8 A;  2DF5 A;  1X12 A;  4HPS A;  1A2Z A;  1Z8W A;  1IU8 A;  3RO0 A;  4GXH A;  1AUG A;  1IOI A;  1IOF A;  1Z8T A;  1X10 A; 
#chains in the Genus database with same CATH topology
 3F8K A;  4A95 A;  4ORF A;  3D68 A;  2X7B A;  5KTD A;  4R8F A;  2Q4Y A;  2Z3L A;  3FX6 A;  3GIU A;  3H8G A;  4W9Y A;  1PUA A;  3SI0 A;  3K9U A;  4RN7 A;  1I21 A;  1TKJ A;  2Q51 A;  2WYR A;  1CJW A;  4UA3 A;  4UCN A;  3D67 A;  2JDD A;  3D2P A;  4KOV A;  1TKH A;  4B6Z A;  2GE3 A;  4UBR A;  3CXS A;  3FYN A;  4H2K A;  1R3N A;  3LD2 A;  3PB4 X;  3PBB A;  4CGM A;  1Q2C A;  3PB8 X;  4R87 A;  1KUV A;  2VZZ A;  3ISZ A;  3LMS A;  4UFX A;  5HVF A;  2NYQ A;  3B7I A;  3F0A A;  3NH5 A;  3PB6 X;  1M1D A;  2Q4Z A;  2B58 A;  4MCQ A;  3NE8 A;  3GUX A;  5HH1 A;  4UFW A;  1LRZ A;  1ZLI A;  2DEA A;  3BI0 A;  4U5Y A;  3IWG A;  2ZOG A;  1B87 A;  5EMI A;  3GY9 A;  4A30 A;  4YRH A;  4ZGY B;  3PFE A;  3OWC A;  2Q4V A;  3CXQ A;  3QAH A;  3FF3 A;  4C2X A;  1FNO A;  2YGW A;  3SJE A;  5JQ4 A;  4QB9 A;  4PXD A;  1IY7 A;  3GLJ A;  2ZW4 A;  4ZX8 A;  4LUA A;  2POK A;  2PJ3 A;  4UCP A;  3TO7 A;  4KVM E;  3I3G A;  3ZZI A;  3NH8 A;  4PXC A;  3BXM A;  4C7I A;  3I1U A;  3QAY A;  1KUY A;  1XJO A;  2RFH A;  4JXR A;  5G22 A;  4B14 A;  5J1Q A;  3KL9 A;  3B35 A;  4C7H A;  3R1K A;  3BJ8 A;  1BPM A;  4EFD A;  1KUX A;  4DUK A;  1YX0 A;  2OB0 A;  4A32 A;  4ONW A;  3PP9 A;  5EC4 A;  3T9Y A;  2PJ5 A;  2BO9 A;  2G0B A;  1UFH A;  2G9D A;  4OC4 A;  4AB7 A;  5A28 A;  1P0H A;  3S6F A;  1NSA A;  2Q43 A;  3UY5 A;  3PB9 X;  4KLV A;  4MFP A;  3B3W A;  1YR0 A;  2R8V A;  3DR6 A;  2FCK A;  4MMO A;  4WWV A;  3WC6 A;  3P2H A;  4MY0 A;  2F7V A;  3DLJ A;  2DF5 A;  2JEW A;  1MJ9 A;  3BHX A;  5G1Z A;  3L2N A;  4CGP A;  4UIA A;  3VWE A;  1IGB A;  3S6G A;  4E8O A;  4JD6 A;  1TIQ A;  1YRE A;  3PRT A;  1YSJ A;  3FEE A;  3PZJ A;  4OLL A;  4PK3 A;  2FE7 A;  3P2F A;  4KUA A;  3KGQ A;  1S7K A;  2IQ6 A;  1UWY A;  3D66 A;  3IC1 A;  3NE7 A;  2FL4 A;  3KAS A;  3K9T A;  1AYE A;  4KOX A;  5LYD A;  3N7Z A;  3WC7 A;  2IMO A;  4MJ8 A;  3SJF A;  2YND A;  3CPA A;  4ZY0 A;  3R9F A;  1XEB A;  5AG7 A;  2V8D A;  4YWY A;  3ZJ0 A;  3KQZ A;  3NFZ A;  2D4P A;  4PV6 A;  4ZYQ A;  1ELL P;  4FD4 A;  4BBH A;  5K8N A;  2BSW A;  1CPX A;  4NSQ A;  3NA6 A;  5KTA A;  1IU8 A;  4UWJ A;  4E2A A;  4KSF A;  1U6M A;  1Z2L A;  3PGP A;  2ZEP A;  3S9N A;  2B4D A;  1QQ9 A;  4A2Z A;  4F6A A;  1BPN A;  2EK8 A;  5JM6 A;  5K8M A;  3V8I A;  3S6K A;  5EBV A;  2C6C A;  1MK4 A;  2NMT A;  2HV2 A;  3SI1 A;  5G20 A;  2ZEE A;  1X10 A;  2ODF A;  2Q7B A;  4CRZ B;  1IB1 E;  4ZY2 A;  2PR8 A;  3IO1 A;  2NSM A;  2O28 A;  3SJG A;  3R95 A;  1Z9U A;  2RB7 A;  1M4L A;  4P44 A;  3TOB A;  4OID A;  2PJ1 A;  2ZW7 A;  4CGN A;  5IV0 A;  2PJ7 A;  3F5B A;  4YU9 A;  4NF1 A;  1GHE A;  1K4J A;  3JRU A;  3NH4 A;  4UWI A;  1S3Z A;  5CNP A;  2DPS A;  2ANP A;  4YGO A;  3B3C A;  3B3V A;  4GXH A;  2I79 A;  4A38 A;  4KVO E;  2B5G B;  3CZX A;  1Y7E A;  4OME A;  3W6X A;  4XPD B;  2BL1 A;  2J9A A;  3H8E A;  1Z4E A;  4AG7 A;  1BOB A;  3PBE A;  4P4B A;  2CIJ A;  1R57 A;  4B5P B;  2FXF A;  4JZ0 A;  2PC1 A;  2CNS A;  4UEZ A;  1NSL A;  2ZPA A;  4R57 A;  1CG2 A;  1Y0R A;  1Y9K A;  3B2Y A;  3KHZ A;  2PJ9 A;  2HC9 A;  2D4O A;  5H86 A;  1V0C A;  4PK2 A;  1ARM A;  4NGR A;  3FJU A;  4MHN A;  2CF4 A;  2J8M A;  4QC6 A;  1M4G A;  4JYW A;  4R9M A;  1YLE A;  4JLY A;  2FS5 A;  3FNC A;  4NXY A;  3S9L A;  1YW6 A;  4HNY B;  3SXO A;  1RTQ A;  2OZU A;  3IFE A;  5AGE A;  4ZI6 A;  4RS2 A;  2CY2 A;  1VHE A;  1B6B A;  4U9Y A;  4Q7A A;  4M6I A;  2BEI A;  4JJX A;  2A4N A;  2JBK A;  3TO9 A;  5THW A;  3D2M A;  1L0C A;  1S7L A;  2OR4 A;  2O4H A;  3S6H A;  1LFW A;  2AFZ A;  3QNV A;  2FVG A;  1HDU A;  3FBU A;  3G8W A;  3D7G A;  3IU1 A;  5D8N A;  1Z5R A;  4FAI A;  1JQG A;  2HUZ A;  3RAM A;  1OZP A;  2AJ6 A;  3GYA A;  1CPS A;  5LYF A;  2VL1 A;  4L89 A;  4X3R A;  4II9 A;  1XFO A;  4PSX A;  2PVW A;  5J8C A;  2VEZ A;  4OP4 A;  3CDX A;  1F2P A;  1ZO0 A;  4NGS A;  5LRJ A;  1QMU A;  1IIC A;  2Z3N A;  2OU2 A;  3V7Z A;  5K8O A;  4C68 A;  1AUG A;  2ZEG A;  3TFY A;  4OKO A;  3TT2 A;  1YK3 A;  4A31 A;  2R1I A;  3FMC A;  3D3S A;  2WPW A;  2AFM A;  2GLJ A;  1S5K A;  2Z3M A;  4UCM A;  2XEG A;  4NGQ A;  1Z8L A;  3DR8 A;  3E0K A;  5C88 A;  5FVJ A;  1SQH A;  4Q38 A;  3D4U A;  3TC8 A;  5DS0 A;  3FXT A;  3W91 A;  2CTC A;  4R6T A;  4KSA A;  2QEC A;  4C2Z A;  1PU9 A;  2ARH A;  4H6U A;  1QSR A;  4A94 A;  2FSR A;  2IJZ A;  4XNH B;  1XBU A;  5F48 A;  3FIX A;  4P4J A;  8CPA A;  4NGP A;  1VGY A;  2VXK A;  4MFZ A;  1LAP A;  1XE4 A;  4J3G A;  1XIX A;  4XPK A;  5AG6 A;  3TOA A;  5KTC A;  4OAE A;  2G3T A;  3MRU A;  3D8P A;  4EWT A;  2IL4 A;  2C1C A;  2REF A;  5DWM A;  4MCP A;  4I49 A;  2PJ6 A;  4KOR A;  2JBJ A;  2PJA A;  4MXU A;  5H84 A;  1ARL A;  2ZW5 A;  4C2Y A;  5D29 A;  2JEV A;  4GS4 A;  4PPZ A;  4X8I A;  3R96 A;  3TO6 A;  3TTH A;  4NJQ A;  2PDO A;  4B12 A;  1ON0 A;  4LX9 A;  4F9V A;  2R98 A;  4PXB A;  5E96 A;  2EBJ A;  2PIZ A;  4P10 A;  1S7N A;  4UEF A;  2O53 A;  4CYO A;  2CXA A;  3LAC A;  4P45 A;  4BD9 A;  4ZBG A;  4IAV A;  1YW4 A;  2DXQ A;  2V8V A;  3RBU A;  3MGD A;  3KI9 A;  4CRY B;  1H8L A;  1I12 A;  2K5T A;  2C6G A;  2PJC A;  2V8H A;  3GKR A;  3EY5 A;  3GB0 A;  1S60 A;  3CT9 A;  3KHX A;  4AVB A;  1AMP A;  3JVN A;  4Q36 A;  1XF8 A;  1HDQ A;  4AVC A;  4CGL A;  1CP6 A;  1NE9 A;  1IOI A;  5F47 A;  3IWW A;  4B13 A;  4LQG A;  4QVT A;  4MI4 A;  1YQE A;  1LAM A;  4P4I A;  2PR1 A;  3FB3 A;  1ZG7 A;  2PJ8 A;  3IEH A;  3TX8 A;  3SJX A;  4FWU A;  1XMT A;  4P4D A;  2BOA A;  4NJR A;  4TWE A;  1DTD A;  4OC5 A;  5CBM A;  4NGM A;  2EUI A;  4KSI A;  1ELM P;  3BLN A;  5LRK A;  1Q2D A;  3VWD A;  3TE4 A;  3B8G A;  3I9S A;  4P4E A;  3DSB A;  5GCN A;  4HPS A;  2YNE A;  4KOS A;  4KS9 A;  3WAB A;  2PIY A;  2KCW A;  1Z8W A;  1Y9W A;  2PJB A;  2G3A A;  2I00 A;  2XEI A;  5LYI A;  2PRQ A;  4NEX A;  3EFA A;  2ZED A;  2F5I A;  3R9E A;  3T90 A;  3KKW A;  4XPD C;  4RI1 A;  2AFU A;  3PEI A;  3EO4 A;  4WJB A;  4MCS A;  3D7F A;  4CYN A;  3ISX A;  1I1D A;  4DNC A;  4M3S A;  5IB0 A;  1MJA A;  4CGO A;  4E0A A;  4KVX A;  3DGV A;  3BJ7 A;  3JUW A;  2B4B A;  1P4N A;  4HNX B;  2VZY A;  1YME A;  2ZW6 A;  3IU2 A;  2WUU A;  4AG9 A;  2AFO A;  4IHM A;  4KOY A;  4CS0 B;  4M6G A;  4EVY A;  5BWA B;  5HMN A;  5HVG A;  4ZY1 A;  1EE3 P;  2QYV A;  1CP7 A;  4X2T A;  1FT7 A;  4QUS A;  4R76 A;  4MFJ A;  1VKC A;  4B5O A;  3SHP A;  2H5M A;  2YNC C;  4ONU A;  4JWP A;  2AFS A;  4P6Y A;  4KUB A;  2GFQ A;  4R3L A;  2OZH A;  3H8F A;  1M4I A;  4ZX9 A;  3DNS A;  3G3S A;  3KR5 A;  1PYT B;  2WZN A;  3LWU A;  2Z11 A;  1QSN A;  2PSW A;  2Q44 A;  3WR7 A;  4H6Z A;  1TF8 A;  4KOW A;  4A33 A;  4L8A A;  4B10 A;  4IUS A;  4LQ6 A;  4MHZ A;  5I4M A;  2XEF A;  7CPA A;  2JLM A;  1TXR A;  2Z10 A;  3H5Z A;  4MHY A;  2Z3K A;  2I3C A;  1Z8X A;  2ZEL A;  4NFR A;  2AE6 A;  4BMH A;  4KLW A;  4F0X A;  2PJ0 A;  1Q7L A;  4Y49 C;  3WT4 A;  4BIN A;  4DJL A;  2P6F A;  4Y49 B;  1X12 A;  2RC4 A;  3TCV A;  4UFV A;  1IYK A;  4FD6 A;  2Z0Z A;  3EC4 A;  2PRB A;  4HKF A;  1KWM A;  1RXT A;  3RO0 A;  3H4Q A;  3KR4 A;  4HNW B;  2GU2 A;  3VH9 A;  2ZEN A;  2PE3 A;  3FED A;  4DYO A;  5F49 A;  4F8Z A;  3V38 A;  5J8F A;  1Q2Y A;  4NGT A;  2OZG A;  2J8R A;  1GYT A;  1LAN A;  2QIR A;  2ZXV A;  2ZEO A;  1OBR A;  3BI1 A;  2P6E A;  2ZEH A;  2Z3P A;  2ZEF A;  3A9L A;  1JWQ A;  3IJ3 A;  1M4D A;  4A37 A;  5G21 A;  2EO8 A;  3FRM A;  4XNH C;  2CNT A;  3C26 A;  2Y0M A;  2PJ2 A;  5A27 A;  2B3V A;  2REE A;  3SI2 A;  2FIW A;  4OC3 A;  1FY7 A;  2P0W A;  2QML A;  3K2K A;  2Q7S A;  3EXN A;  2C27 A;  2QJ8 A;  3FEC A;  2GAN A;  1LOK A;  1WK4 A;  1VIX A;  4OC0 A;  1CX8 A;  4CAW A;  4B11 A;  1DE4 C;  2PJ4 A;  2PQ8 A;  3D7H A;  1VHO A;  5JH9 A;  2FT0 A;  2F8H A;  5HVH A;  2BUE A;  3HUV A;  5LRG A;  1Y7R A;  1S7F A;  2PVV A;  4UIB A;  2VI7 A;  5F46 A;  2VQY A;  4EME A;  2EK9 A;  4CYQ A;  4CYP A;  4CAF A;  1Z8T A;  1YGH A;  4M6H A;  3RZA A;  3CXP A;  4OC1 A;  3T8W A;  1TKF A;  2QVP A;  4IK2 A;  2V77 A;  3IWE A;  3RNZ A;  3MN8 A;  1TF9 A;  1RO5 A;  1QSM A;  2JDC A;  4MFK A;  4QBJ A;  1XMB A;  2ATR A;  2GLF A;  4CAE A;  2CTB A;  5ISV A;  1LCP A;  4Z65 A;  3B3S A;  1VHS A;  2PCU A;  3CPX A;  2HQY A;  2WPX A;  1XOV A;  1F57 A;  3D7D A;  3IGR A;  4A39 A;  1NMT A;  2HB6 A;  5AG4 A;  4OC2 A;  1QSO A;  3QB8 A;  3PB7 X;  4FD7 A;  2V8G A;  4KZT A;  4OAD A;  4AXV A;  2P6G A;  2B5G A;  1BAV A;  1YLO A;  3R9G A;  4YFJ A;  1PCA A;  4PSW A;  4NGN A;  5F09 A;  1F2O A;  1HEE A;  2BCO A;  3W6S A;  4B5P A;  5JPH A;  2VBQ A;  5CPA A;  4F0Y A;  4UEE A;  1XRY A;  4PXE A;  3RYO A;  6CPA A;  2C6P A;  4G1P A;  3FVL A;  1ZLH A;  2ABZ A;  1YVK A;  5K8P A;  4U9Z A;  5I0C A;  3N5F A;  4FD5 A;  2J8N A;  3HLP A;  4MCR A;  4NCZ A;  4X5K A;  1A2Z A;  3S9M A;  1ZG9 A;  2ZEM A;  1KZF A;  3VAR A;  2AFW A;  5DWN A;  2GRE A;  4F9U A;  2B3U A;  5HXD A;  4TNU A;  2OOT A;  1IID A;  2YNC A;  1IOF A;  2OH1 A;  2ZOF A;  4OIW A;  4MFL A;  5ELY A;  4KOU A;  5AG5 A;  5IB9 A;  1BLL E;  1IYL A;  2Q04 A;  4IF5 A;  4PQA A;  4CAX A;  5LYL A;  4M85 A;  2Q0Y A;  3DDD A;  3VAT A;  1ZG8 A;  4MFQ A;  3FH4 A;  3WC5 A;  1Z4R A;  1M44 A;  5IX3 A;  1CM0 A;  1J4J A;  4MHD A;  4RUH A;  1BO4 A;  4CPA A;  4KOT A;  1CBX A;  3KZW A;  2Z3O A;  2R7H A;  4CAV A;  2EWB A;  5JGF A;  3PFO A;  2EVN A;  4P4F A;  2XEJ A;  4AVA A;  4K3N A;  1MJB A;  4GM5 A;  4R7M A;  2FIA A;  2AFX A;  3JTK A;  4XPL A;  2DPT A;  4R3K A;  3KQX A;  1Y0Y A;  3B3T A;  2B4D B;  3LOD A;  4H89 A;  2CNM A;  4MRI A;  3SXN A;  4FBE A;  5C82 A;  2WSA A;  1YVO A;  4MBU A;  4JXQ A;  4K30 A;  2GIV A;  1WWZ A;  4FUU A;  4MHP A;  3IIB A;  4O23 A;  4MY3 A;  1N71 A;  1QST A;  4UF4 A;  1R43 A; 
#chains in the Genus database with same CATH homology
 2EBJ A;  3RNZ A;  3LAC A;  3GIU A;  1Z8X A;  2EO8 A;  2DF5 A;  1X12 A;  4HPS A;  1A2Z A;  1Z8W A;  1IU8 A;  3RO0 A;  4GXH A;  1AUG A;  1IOI A;  1IOF A;  1Z8T A;  1X10 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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