1LE2A

Structural basis for altered function in the common mutants of human apolipoprotein-e
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
144
structure length
144
Chain Sequence
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKCLAVYQAGA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Salt bridge relay triggers defective LDL receptor binding by a mutant apolipoprotein.
pubmed doi rcsb
molecule tags Lipoprotein
source organism Homo sapiens
molecule keywords APOLIPOPROTEIN E2
total genus 57
structure length 144
sequence length 144
ec nomenclature
pdb deposition date 1991-08-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.20 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Apolipoprotein 1le2A00
1LS4A 1EA8A 1H7IA 3R2PA 1LPEA 1EQ1A 1YA9A 1AEPA 1NFNA 1OR2A 1B68A 2KC3A 1LE2A 3S84A 1LE4A 1OR3A 1GS9A 1BZ4A 1NFOA
chains in the Genus database with same CATH superfamily
5A6AA 2YVKA 2NSFA 1VLSA 2Q9AA 1MMAA 3WG7C 4EIYA 3QW1A 1JPJA 1C17M 4U5HA 4PK4A 1M2VB 2B0HA 3NRHA 3T6BA 1G8XA 3DWWA 3WODF 2HV6A 4IARA 2Q9CA 4MS2A 3TJ5A 2D4UA 1YA9A 4IRUA 4OIQF 4E7ZA 2YKZA 1YA7O 2G3VA 5CI8A 4E0IA 3AG3C 4XLNF 2ASRA 1OQCA 1OW8A 3GANA 4MW3A 1O5HA 3RIPA 1ST6A 4ANJA 2XLEA 4DVZA 3EG9A 1ZHXA 4JIOA 3C8GA 2LCHA 3KKBA 2L6FA 3B29A 2VCAA 4IB4A 4Z9HA 1DOWA 4DRHB 3J06A 5E3CA 2J9UA 3DJUB 2MWQA 4N4WA 5BQIA 4CDVA 1YARO 4GQHA 3ECSA 4F4BA 3A9CA 1RJ9B 5L0HA 4JW1A 4Z9JA 1HMDA 4RBNA 4JTDB 3TK0A 2EINC 3KYIA 3O39A 1NLXA 2OCCC 4EHPA 2QE9A 2UUHA 3AJMA 1V74B 3MX3A 4JCZA 4CJGA 2LSEA 3G50A 3UMKA 4E18A 2Y3HA 1K04A 2AVKA 3BRJA 3S27A 4D4NA 4KC9A 2YEVA 3JYYA 3S9OA 5DLJA 4MVZA 5K0IA 1IW7F 1QZXA 1E83A 2R7VA 5KYYA 4Q7CA 2KGOA 4L6RA 1A0BA 1D1BA 4LDQA 2HMZA 4U5EE 4I3MA 4U5GA 4DVYP 2FGYA 2OJQA 2PF4E 1PCXA 3C62A 3FOOA 3K1HA 4KBLA 4C3DA 4CBEA 4YT4A 4PJMA 1VYKA 5JS5A 2WVOA 4MVOA 1MQVA 2F22A 3FHDA 1NFOA 3IPMO 1TR2A 3TOMA 3US6A 3ZC4A 4I44A 5B3SC 3UGOA 2Y69C 4Q4ZF 2OEVA 1UG7A 3UGPA 1H7IA 2H7VC 4AX2A 2BE5F 2OOCA 2HS5A 2GFHA 4AE4A 4YN0B 4WGYA 3JCUQ 1SF8A 2A0BA 4A4AA 5AGFA 3O10A 2XL6A 1EQ1A 1BR4A 3RVYA 4YL3A 3GM3A 3GORA 1Z6AA 3GODA 3EGXB 4JURI 3DE8A 4DRJB 4ZLCA 5EK0A 1V4AA 1OKKA 3O55A 4KNWA 3C7JA 5D92A 1UFBA 4NTAA 3PDMP 5DS5A 3U9MA 1Y4CA 4FX5A 4LERA 1FTSA 2IOQA 3PMRA 1J8MF 3OWTA 2ICWG 2R7TA 1J8YF 3RFYA 3H2UA 2M64A 3MFNA 2XLVA 4JJGA 4O7GA 2DI3A 3TJ6A 2XL4A 2A68F 3EJNA 1D1CA 5KYXB 2WL8A 4OINF 1U0BB 2ZXOA 1WGWA 3EZHA 2YQYA 1TWGA 3L8JA 4QI0A 1HE9A 2DYRC 1YJGA 2NUPB 2R7QA 4GEHA 3EPVA 2IXMA 3ZVRA 5AC4A 2EPMX 4XLPF 2VCCA 3HLZA 4U9DA 2XS1A 2LFDA 3QZCA 1KU2A 2NUTB 4CS9A 4CS9C 3M1CB 4Q5SF 5JLIA 1RJ9A 2QNLA 1MNDA 2GAQA 5E33A 1OCZC 1LS1A 4MVQA 2EPOA 2LIGA 3KL4A 2J9VA 4N06A 3TD7A 1LE2A 1VMAA 3V7OA 2J9BA 1C03A 2HV7A 3H2VA 4JE9A 3TOLA 5A6BA 3EH2A 4YT8A 1NU7D 3I5QA 4N6HA 3M15A 3HNJA 2JPUA 2GA0A 5T1DB 4X0RA 4FESA 4YT2A 2YRFA 3EZIA 4HEAJ 1M57C 3EQLF 1FFHA 3NYJA 3L1MA 1WASA 4EWCA 3PHF2 3UMIA 2EPKX 3O6XA 5BQGA 4OIPF 4AL0A 4J30B 3S0XA 1ZZPA 4XEVA 4AL1A 5A6JA 5L3QA 3SNHA 1E85A 4CIPA 3LEOA 2R9RB 3OA1A 1LIHA 2Q3TA 3SEOA 3RKOF 2R7OA 1O87A 2FAPB 3NMKA 1E86A 2PX3A 1NFNA 1ZHWA 1FMWA 3RQFA 3ABMC 1APCA 4MVMA 1V55C 3RH3A 3RQGA 1U89A 2Z15A 4B6IA 1G5ZA 1VTMP 1CGNA 5DVWA 3LLIA 1BR2A 3LUTB 4U9EA 1YYXA 5B1AC 4K7BA 4P9TA 5L0CA 5D91A 1JPNA 2Y39A 1VLTA 4C7OB 3EGXA 3Q6MA 1G4US 3B0PA 3DAFA 4CSAC 4CSAA 4BEJA 1GM5A 1Q0GA 2YL7A 1PD0A 2G3KA 1DOVA 2OKUA 3C18A 2P1AA 4RD9A 4DJ9A 4MVUA 3JRTA 2R25A 3LJBA 4HFKB 4PJNA 1WTYA 5KYWB 1RXQA 2L9JA 3OEOA 2LQGA 2Y3BA 2C03A 4BG0A 1HMOA 1MMDA 1ZHZA 2J45A 3C8ZA 2CNWA 3KMIA 3GEEA 5KYXA 3JZ0A 2XLWA 1H6GA 1T6UA 3E70C 4PR9A 4JC7A 3WAQA 2TMVP 3WHNA 2VC9A 4JEBA 1C02A 3K66A 2X51A 3VYWA 5AC5A 1HE1A 1IZMA 2NUPA 3FOPA 2KYHA 5A69A 2KSFA 3S90A 2XXAB 4BJTA 3W2VA 2YLDA 3K33A 3GWLA 3DJNB 2NUTA 4YT5A 1GQAA 1NSGB 1OR3A 2HSQA 4O6NA 3IQ6A 5T3TA 1SYQA 1BZ4A 3CEXA 4O79A 1T6IA 3ZTZA 3M4BA 1TFOB 4EBJA 4YL0A 4CDAA 5L0JA 4J32B 5FZTA 2ZXRA 3MLGA 4YJWA 4P6IC 1MMNA 3DM9B 2QUPA 1JAFA 1RKEB 1H9TA 3GM1A 4K0DA 2XL8A 1LKXA 3DE9A 3RVZA 4U5FE 1XZPA 2WB7A 4CJOA 2J0XA 2EILC 4FAPB 2XLDA 3C63A 1QKRA 4OIRF 3U8VA 2KW3C 4CS7A 2LD6A 3LLKA 3ZSUA 3ZDLA 2HJMA 4QI2A 2J8WA 3FAJA 1XZQA 1Z3IX 3TQOA 3AGTA 1ORYA 2I8BA 3DD7A 4G7HF 3T9OA 1OXKA 4W8KA 1VK5A 2Q4FA 1Y6DA 3HKKA 1LS4A 4OD5A 1M6TA 2AP3A 3CZ6A 3B71A 2YHSA 2B0JA 3ZTMA 3CQZA 3LS0A 1QPUA 3H65A 4IAOA 3AQCA 5JVEA 2RSEB 3G4ZA 4N6CA 3RQEA 2HUJA 2NG1A 2QLAA 5COFA 5F5HA 4C7OA 3R7CA 3C8GD 1E2XA 2R05A 3NDBB 3HNKA 4PJLA 3F46A 3AG4C 2M4EA 4XWJA 2VB6A 3W8IA 5DQTA 2WVNA 4XTKA 4FWVA 2Y3GA 2ZD9A 3T4RA 2HZ8A 3MYIA 1M2VA 5KYWA 2ZXWC 1OW7A 1ZU4A 1TWCA 5L0FA 3KPHA 3Q7LA 2PX0A 2NPUA 4MTOA 3NYLA 2QTVA 1YVIA 2EIJC 4QDLA 2H7OA 4O6MA 3AQBA 3L8IA 2OEXA 5GPGB 4C3BA 3IQCA 4M63A 3JT1A 1BDJB 3EFOB 1OCOC 1EA8A 1WWPA 1QLEC 3ATPA 3SXMA 3EGDB 5A6KA 4CIHA 2XXAA 4CDYA 3T6GB 2YLGA 3HNLA 1R5ID 3MYFA 3FMSA 2KJGA 1YLMA 2W4MA 3QVYA 5COMA 5BUOA 4MVSA 2XM4A 2W4BA 1YAUO 3RW0A 3S29A 2J7PA 3U0CA 2IBFA 4KI2A 2EIKC 1QQ3A 3U8PA 2WZFA 2XM0A 3NYMA 3DKAA 4HFFB 1TWAA 3A11A 3MBGA 3L0IA 4G7ZF 1VB5A 4XEKA 2Q9BA 2AWYA 2OG2A 4LDRA 1N1CA 2W45A 3JTLO 4MVRA 2Q00A 2X0CA 3QVZA 3S28A 1RMVA 3QW0A 2IM8A 2YL0A 3LAYA 1S7ZA 1I5NA 1T5OA 3DMDA 5FCLA 3NKDA 1HW2A 4KNVA 1Q0DA 3FAPB 4MNDA 3R2PA 1OKKD 3SZRA 3X2QC 2I15A 4U5CE 4EUKB 2KK1A 5F28E 1LPEA 2IXNA 3POVA 4BJ6C 1OCCC 2IXOA 2DYSC 3JSZA 1WATA 1VOMA 5EGYA 1Z5ZA 1FAPB 2HMQA 3KYJA 3LESA 3CSKA 5CI9A 1ZYRF 256BA 3M79A 1NBBA 4PFPA 1SZIA 3W8HA 4DRIB 3DZAA 2KC3A 5B3IA 1I4ZA 1LE4A 1TWHA 3JRMO 5JP7A 4IJJA 1D1AA 1LVKA 2YLIA 4CS8C 3UNGC 2JX0A 4J7YA 1O3UA 3M4CA 2DGJA 3SP1A 1D0YA 1KTMA 4JVSA 1A7EA 3IQTA 4LACB 4PACA 5L0IA 2E87A 1QVXA 4WGZA 1S05A 2WZGA 4ULWA 1K40A 4BPMA 2PP4A 2R7SA 3IEEA 4E0HA 1WN0A 1YZAA 2O9XA 4LLEA 4NCQA 5A6BD 2WZLA 1M56C 1NZEA 1OW6A 3U2LA 3V5YA 1EKYA 1Q0FA 4LDKA 2MHRA 4NTBA 3N0TA 5E3AA 3SXYA 1F1MA 4XPYA 1A7VA 2HJ3A 4OD4A 4DOZA 2CW0F 1YDIA 1M2OA 2NSGA 3EHNA 1HW1A 4ONSA 4DXWA 3RF3A 4EBKA 3ABLC 2KQ9A 2OU6A 4AE4B 1E84A 1ZHTA 1A41A 3AGUA 1JR8A 3SXKA 2P7VA 1FR0A 2L81A 3ASOC 1TQGA 4YWQA 3IQ5A 4O6YA 5BQHA 2MYSA 4XQ1A 5E2QA 1CPRA 2D5RB 4WJ0A 1RKCA 3E9VA 5B1BC 3ZIBA 5HV9A 2PBEA 1TFKB 1BR1A 1JMWA 2QY9A 4LLCA 1Z7Qc 5KYNA 3GWNA 5IY5C 1A7DA 4YL1A 2J9WA 3HNIA 4MTFA 3JSEO 3UMHA 3GEHA 3U9JA 3U2MA 3L34A 2ETSA 3NKEA 3QTHA 2EPLX 4GYTA 3FDQA 4AK9A 2FFHA 3K6BA 4H54A 4BEMJ 3LNRA 5TJ5E 3ZG1A 3IHUA 2A1DD 4IWBA 4RDAA 2H7BA 4ER9A 5KYUB 3VAYA 1MMGA 2AU5A 4HE8D 2R7WA 2YL1A 3B0UX 2CNWD 4OIOF 1T01A 2XLHA 1LI7A 1NU9C 4JKVA 4YK5A 3U3BA 1ORJA 3W2WA 2R7RA 5JRAA 3DAGA 3LNMB 2GWWA 1MNEA 2C04A 4EKWA 2R7XA 5JUAA 3TULA 2ZXPA 4K1OA 5F5FA 2R03A 4A2NB 3EHMA 1Q0MA 1ZVZA 3V5XA 2LFFA 2YWAA 4BJ5C 1XWJA 4BJ5A 2H8AA 2IXPA 1PV3A 2J46A 1LI5A 1CPQA 1JRAA 1V54C 4J7TA 1B68A 3K1IC 3K1IA 5EHHA 1AVOB 1CGOA 1Q0KA 4NTFA 2HSBA 4PFOA 2P6VA 4Z9IA 3V5ZA 2V26A 2L6HA 2V3CC 2YZSA 5CIVA 5L3VA 2CYDA 1EI7A 2KNHA 1YZCA 4ZLDA 4WABA 2G62A 4E17A 5DS4A 2A0UA 1U6HA 1LM3B 2IYLD 2WVQA 1WOLA 1L3PA 3ZQYA 4W8PA 3ZWIA 3VRCA 1TKNA 3DXJF 4JJFA 3FVYA 1FFTC 1VYIA 2Q7RA 4NC3A 4BJ1A 1K05A 4C3EA 1NG1A 4IGGA 1I4YA 2LK4A 2A6EF 1AEPA 2P0NA 4E7SA 4P9FA 4U5DE 3HTKC 4JZAA 5DQZA 2LP4A 4EBBA 3S84A 3Q7GA 1Z63A 3N24A 2BL2A 4IAQA 4U5BE 2EPNA 2J0WA 1RKEA 3ITFA 2XLMA 1AUEA 1KNYA 2CDQA 3ABKC 2VCBA 3B0VC 4D4XA 4MW8A 1H9GA 1Z23A 2RD9A 2UUIA 2HKVA 3AG2C 3B9QA 1BBHA 1R4TA 3BEHA 3HJCA 3CAXA 3K7DA 2HFIA 2R7UA 3QMKA 3SXZA 1T6QA 1W2WA 1FNTc 4PJJA 3U3FA 3NG1A 1G4WR 4G0HA 5KYUA 5COGA 2OQMA 3NMIA 1D0XA 4G7OF 3EG9B 4H4KC 2P61A 3VM6A 4ULVA 3C8GB 4BJ6A 3I4UA 1SMYF 5DS6A 3F47A 3DI5A 4I1OB 2A69F 3GEIA 4MTGA 3U5SA 1OR2A 2XSEA 2XS8A 2R02A 1CGME 1ZHYA 3W4YA 1ZW3A 3FXHA 1GGQA 1L7CA 2PFDA 4MQ9F 2YL3A 4JEAA 2A6HF 3JYHA 3Q6NA 5JT4A 2L7AA 4NY3A 1ZU5A 2VASA 2ZPAA 2AWCA 1YYJA 4CS8A 2J7PD 4I1MA 4XPXA 1PD1A 3ZQVA 1FMVA 3PCVA 4DBRA 2W9YA 4R32A 3DM5A 3LS1A 3NMJA 2L6GA 4XEFA 5JSLA 3EH1A 1ZW2A 5KYYB 1ORSC 1OXBA 3N2ZB 2GDCA 3T6JA 4DBQA 2EIMC 2VH3A 4JRZA 4JTCB 2PNOA 2JD3A 3AG1C 3GM2A 3ASNC 2XRHA 2CGEA 3I5PA 4JTAB 4CX9A 5HSWA 4XPWA 3EFOA 3VF0A 2OJED 1D0ZA 3AOUA 3LEVA 5L0DA 1JOGA 3EGDA 5T3WA 3G4XA 3RYLA 3SYNA 5L0GA 1RCPA 3X1OA 1HY5A 2Y3DA 2BC5A 1SR2A 1T9KA 4G78A 2DB4A 4JCHA 2CCYA 2XLOA 1GS9A 3KH2A 4UDVA 4NQFA 3UR3C 1QSPA 1OCRC
chains in the Genus database with same CATH topology
1LS4A 1EA8A 1H7IA 3R2PA 1LPEA 1EQ1A 1YA9A 1AEPA 1NFNA 1OR2A 1B68A 2KC3A 1LE2A 3S84A 1LE4A 1OR3A 1GS9A 1BZ4A 1NFOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LS4 A;  1EA8 A;  1H7I A;  3R2P A;  1LPE A;  1EQ1 A;  1YA9 A;  1AEP A;  1NFN A;  1OR2 A;  1B68 A;  2KC3 A;  1LE2 A;  3S84 A;  1LE4 A;  1OR3 A;  1GS9 A;  1BZ4 A;  1NFO A; 
#chains in the Genus database with same CATH topology
 5A6A A;  2YVK A;  2NSF A;  1VLS A;  2Q9A A;  1MMA A;  3WG7 C;  4EIY A;  3QW1 A;  1JPJ A;  1C17 M;  4U5H A;  4PK4 A;  1M2V B;  2B0H A;  3NRH A;  3T6B A;  1G8X A;  3DWW A;  3WOD F;  2HV6 A;  4IAR A;  2Q9C A;  4MS2 A;  3TJ5 A;  2D4U A;  1YA9 A;  4IRU A;  4OIQ F;  4E7Z A;  2YKZ A;  1YA7 O;  2G3V A;  5CI8 A;  4E0I A;  3AG3 C;  4XLN F;  2ASR A;  1OQC A;  1OW8 A;  3GAN A;  4MW3 A;  1O5H A;  3RIP A;  1ST6 A;  4ANJ A;  2XLE A;  4DVZ A;  3EG9 A;  1ZHX A;  4JIO A;  3C8G A;  2LCH A;  3KKB A;  2L6F A;  3B29 A;  2VCA A;  4IB4 A;  4Z9H A;  1DOW A;  4DRH B;  3J06 A;  5E3C A;  2J9U A;  3DJU B;  2MWQ A;  4N4W A;  5BQI A;  4CDV A;  1YAR O;  4GQH A;  3ECS A;  4F4B A;  3A9C A;  1RJ9 B;  5L0H A;  4JW1 A;  4Z9J A;  1HMD A;  4RBN A;  4JTD B;  3TK0 A;  2EIN C;  3KYI A;  3O39 A;  1NLX A;  2OCC C;  4EHP A;  2QE9 A;  2UUH A;  3AJM A;  1V74 B;  3MX3 A;  4JCZ A;  4CJG A;  2LSE A;  3G50 A;  3UMK A;  4E18 A;  2Y3H A;  1K04 A;  2AVK A;  3BRJ A;  3S27 A;  4D4N A;  4KC9 A;  2YEV A;  3JYY A;  3S9O A;  5DLJ A;  4MVZ A;  5K0I A;  1IW7 F;  1QZX A;  1E83 A;  2R7V A;  5KYY A;  4Q7C A;  2KGO A;  4L6R A;  1A0B A;  1D1B A;  4LDQ A;  2HMZ A;  4U5E E;  4I3M A;  4U5G A;  4DVY P;  2FGY A;  2OJQ A;  2PF4 E;  1PCX A;  3C62 A;  3FOO A;  3K1H A;  4KBL A;  4C3D A;  4CBE A;  4YT4 A;  4PJM A;  1VYK A;  5JS5 A;  2WVO A;  4MVO A;  1MQV A;  2F22 A;  3FHD A;  1NFO A;  3IPM O;  1TR2 A;  3TOM A;  3US6 A;  3ZC4 A;  4I44 A;  5B3S C;  3UGO A;  2Y69 C;  4Q4Z F;  2OEV A;  1UG7 A;  3UGP A;  1H7I A;  2H7V C;  4AX2 A;  2BE5 F;  2OOC A;  2HS5 A;  2GFH A;  4AE4 A;  4YN0 B;  4WGY A;  3JCU Q;  1SF8 A;  2A0B A;  4A4A A;  5AGF A;  3O10 A;  2XL6 A;  1EQ1 A;  1BR4 A;  3RVY A;  4YL3 A;  3GM3 A;  3GOR A;  1Z6A A;  3GOD A;  3EGX B;  4JUR I;  3DE8 A;  4DRJ B;  4ZLC A;  5EK0 A;  1V4A A;  1OKK A;  3O55 A;  4KNW A;  3C7J A;  5D92 A;  1UFB A;  4NTA A;  3PDM P;  5DS5 A;  3U9M A;  1Y4C A;  4FX5 A;  4LER A;  1FTS A;  2IOQ A;  3PMR A;  1J8M F;  3OWT A;  2ICW G;  2R7T A;  1J8Y F;  3RFY A;  3H2U A;  2M64 A;  3MFN A;  2XLV A;  4JJG A;  4O7G A;  2DI3 A;  3TJ6 A;  2XL4 A;  2A68 F;  3EJN A;  1D1C A;  5KYX B;  2WL8 A;  4OIN F;  1U0B B;  2ZXO A;  1WGW A;  3EZH A;  2YQY A;  1TWG A;  3L8J A;  4QI0 A;  1HE9 A;  2DYR C;  1YJG A;  2NUP B;  2R7Q A;  4GEH A;  3EPV A;  2IXM A;  3ZVR A;  5AC4 A;  2EPM X;  4XLP F;  2VCC A;  3HLZ A;  4U9D A;  2XS1 A;  2LFD A;  3QZC A;  1KU2 A;  2NUT B;  4CS9 A;  4CS9 C;  3M1C B;  4Q5S F;  5JLI A;  1RJ9 A;  2QNL A;  1MND A;  2GAQ A;  5E33 A;  1OCZ C;  1LS1 A;  4MVQ A;  2EPO A;  2LIG A;  3KL4 A;  2J9V A;  4N06 A;  3TD7 A;  1LE2 A;  1VMA A;  3V7O A;  2J9B A;  1C03 A;  2HV7 A;  3H2V A;  4JE9 A;  3TOL A;  5A6B A;  3EH2 A;  4YT8 A;  1NU7 D;  3I5Q A;  4N6H A;  3M15 A;  3HNJ A;  2JPU A;  2GA0 A;  5T1D B;  4X0R A;  4FES A;  4YT2 A;  2YRF A;  3EZI A;  4HEA J;  1M57 C;  3EQL F;  1FFH A;  3NYJ A;  3L1M A;  1WAS A;  4EWC A;  3PHF 2;  3UMI A;  2EPK X;  3O6X A;  5BQG A;  4OIP F;  4AL0 A;  4J30 B;  3S0X A;  1ZZP A;  4XEV A;  4AL1 A;  5A6J A;  5L3Q A;  3SNH A;  1E85 A;  4CIP A;  3LEO A;  2R9R B;  3OA1 A;  1LIH A;  2Q3T A;  3SEO A;  3RKO F;  2R7O A;  1O87 A;  2FAP B;  3NMK A;  1E86 A;  2PX3 A;  1NFN A;  1ZHW A;  1FMW A;  3RQF A;  3ABM C;  1APC A;  4MVM A;  1V55 C;  3RH3 A;  3RQG A;  1U89 A;  2Z15 A;  4B6I A;  1G5Z A;  1VTM P;  1CGN A;  5DVW A;  3LLI A;  1BR2 A;  3LUT B;  4U9E A;  1YYX A;  5B1A C;  4K7B A;  4P9T A;  5L0C A;  5D91 A;  1JPN A;  2Y39 A;  1VLT A;  4C7O B;  3EGX A;  3Q6M A;  1G4U S;  3B0P A;  3DAF A;  4CSA C;  4CSA A;  4BEJ A;  1GM5 A;  1Q0G A;  2YL7 A;  1PD0 A;  2G3K A;  1DOV A;  2OKU A;  3C18 A;  2P1A A;  4RD9 A;  4DJ9 A;  4MVU A;  3JRT A;  2R25 A;  3LJB A;  4HFK B;  4PJN A;  1WTY A;  5KYW B;  1RXQ A;  2L9J A;  3OEO A;  2LQG A;  2Y3B A;  2C03 A;  4BG0 A;  1HMO A;  1MMD A;  1ZHZ A;  2J45 A;  3C8Z A;  2CNW A;  3KMI A;  3GEE A;  5KYX A;  3JZ0 A;  2XLW A;  1H6G A;  1T6U A;  3E70 C;  4PR9 A;  4JC7 A;  3WAQ A;  2TMV P;  3WHN A;  2VC9 A;  4JEB A;  1C02 A;  3K66 A;  2X51 A;  3VYW A;  5AC5 A;  1HE1 A;  1IZM A;  2NUP A;  3FOP A;  2KYH A;  5A69 A;  2KSF A;  3S90 A;  2XXA B;  4BJT A;  3W2V A;  2YLD A;  3K33 A;  3GWL A;  3DJN B;  2NUT A;  4YT5 A;  1GQA A;  1NSG B;  1OR3 A;  2HSQ A;  4O6N A;  3IQ6 A;  5T3T A;  1SYQ A;  1BZ4 A;  3CEX A;  4O79 A;  1T6I A;  3ZTZ A;  3M4B A;  1TFO B;  4EBJ A;  4YL0 A;  4CDA A;  5L0J A;  4J32 B;  5FZT A;  2ZXR A;  3MLG A;  4YJW A;  4P6I C;  1MMN A;  3DM9 B;  2QUP A;  1JAF A;  1RKE B;  1H9T A;  3GM1 A;  4K0D A;  2XL8 A;  1LKX A;  3DE9 A;  3RVZ A;  4U5F E;  1XZP A;  2WB7 A;  4CJO A;  2J0X A;  2EIL C;  4FAP B;  2XLD A;  3C63 A;  1QKR A;  4OIR F;  3U8V A;  2KW3 C;  4CS7 A;  2LD6 A;  3LLK A;  3ZSU A;  3ZDL A;  2HJM A;  4QI2 A;  2J8W A;  3FAJ A;  1XZQ A;  1Z3I X;  3TQO A;  3AGT A;  1ORY A;  2I8B A;  3DD7 A;  4G7H F;  3T9O A;  1OXK A;  4W8K A;  1VK5 A;  2Q4F A;  1Y6D A;  3HKK A;  1LS4 A;  4OD5 A;  1M6T A;  2AP3 A;  3CZ6 A;  3B71 A;  2YHS A;  2B0J A;  3ZTM A;  3CQZ A;  3LS0 A;  1QPU A;  3H65 A;  4IAO A;  3AQC A;  5JVE A;  2RSE B;  3G4Z A;  4N6C A;  3RQE A;  2HUJ A;  2NG1 A;  2QLA A;  5COF A;  5F5H A;  4C7O A;  3R7C A;  3C8G D;  1E2X A;  2R05 A;  3NDB B;  3HNK A;  4PJL A;  3F46 A;  3AG4 C;  2M4E A;  4XWJ A;  2VB6 A;  3W8I A;  5DQT A;  2WVN A;  4XTK A;  4FWV A;  2Y3G A;  2ZD9 A;  3T4R A;  2HZ8 A;  3MYI A;  1M2V A;  5KYW A;  2ZXW C;  1OW7 A;  1ZU4 A;  1TWC A;  5L0F A;  3KPH A;  3Q7L A;  2PX0 A;  2NPU A;  4MTO A;  3NYL A;  2QTV A;  1YVI A;  2EIJ C;  4QDL A;  2H7O A;  4O6M A;  3AQB A;  3L8I A;  2OEX A;  5GPG B;  4C3B A;  3IQC A;  4M63 A;  3JT1 A;  1BDJ B;  3EFO B;  1OCO C;  1EA8 A;  1WWP A;  1QLE C;  3ATP A;  3SXM A;  3EGD B;  5A6K A;  4CIH A;  2XXA A;  4CDY A;  3T6G B;  2YLG A;  3HNL A;  1R5I D;  3MYF A;  3FMS A;  2KJG A;  1YLM A;  2W4M A;  3QVY A;  5COM A;  5BUO A;  4MVS A;  2XM4 A;  2W4B A;  1YAU O;  3RW0 A;  3S29 A;  2J7P A;  3U0C A;  2IBF A;  4KI2 A;  2EIK C;  1QQ3 A;  3U8P A;  2WZF A;  2XM0 A;  3NYM A;  3DKA A;  4HFF B;  1TWA A;  3A11 A;  3MBG A;  3L0I A;  4G7Z F;  1VB5 A;  4XEK A;  2Q9B A;  2AWY A;  2OG2 A;  4LDR A;  1N1C A;  2W45 A;  3JTL O;  4MVR A;  2Q00 A;  2X0C A;  3QVZ A;  3S28 A;  1RMV A;  3QW0 A;  2IM8 A;  2YL0 A;  3LAY A;  1S7Z A;  1I5N A;  1T5O A;  3DMD A;  5FCL A;  3NKD A;  1HW2 A;  4KNV A;  1Q0D A;  3FAP B;  4MND A;  3R2P A;  1OKK D;  3SZR A;  3X2Q C;  2I15 A;  4U5C E;  4EUK B;  2KK1 A;  5F28 E;  1LPE A;  2IXN A;  3POV A;  4BJ6 C;  1OCC C;  2IXO A;  2DYS C;  3JSZ A;  1WAT A;  1VOM A;  5EGY A;  1Z5Z A;  1FAP B;  2HMQ A;  3KYJ A;  3LES A;  3CSK A;  5CI9 A;  1ZYR F;  256B A;  3M79 A;  1NBB A;  4PFP A;  1SZI A;  3W8H A;  4DRI B;  3DZA A;  2KC3 A;  5B3I A;  1I4Z A;  1LE4 A;  1TWH A;  3JRM O;  5JP7 A;  4IJJ A;  1D1A A;  1LVK A;  2YLI A;  4CS8 C;  3UNG C;  2JX0 A;  4J7Y A;  1O3U A;  3M4C A;  2DGJ A;  3SP1 A;  1D0Y A;  1KTM A;  4JVS A;  1A7E A;  3IQT A;  4LAC B;  4PAC A;  5L0I A;  2E87 A;  1QVX A;  4WGZ A;  1S05 A;  2WZG A;  4ULW A;  1K40 A;  4BPM A;  2PP4 A;  2R7S A;  3IEE A;  4E0H A;  1WN0 A;  1YZA A;  2O9X A;  4LLE A;  4NCQ A;  5A6B D;  2WZL A;  1M56 C;  1NZE A;  1OW6 A;  3U2L A;  3V5Y A;  1EKY A;  1Q0F A;  4LDK A;  2MHR A;  4NTB A;  3N0T A;  5E3A A;  3SXY A;  1F1M A;  4XPY A;  1A7V A;  2HJ3 A;  4OD4 A;  4DOZ A;  2CW0 F;  1YDI A;  1M2O A;  2NSG A;  3EHN A;  1HW1 A;  4ONS A;  4DXW A;  3RF3 A;  4EBK A;  3ABL C;  2KQ9 A;  2OU6 A;  4AE4 B;  1E84 A;  1ZHT A;  1A41 A;  3AGU A;  1JR8 A;  3SXK A;  2P7V A;  1FR0 A;  2L81 A;  3ASO C;  1TQG A;  4YWQ A;  3IQ5 A;  4O6Y A;  5BQH A;  2MYS A;  4XQ1 A;  5E2Q A;  1CPR A;  2D5R B;  4WJ0 A;  1RKC A;  3E9V A;  5B1B C;  3ZIB A;  5HV9 A;  2PBE A;  1TFK B;  1BR1 A;  1JMW A;  2QY9 A;  4LLC A;  1Z7Q c;  5KYN A;  3GWN A;  5IY5 C;  1A7D A;  4YL1 A;  2J9W A;  3HNI A;  4MTF A;  3JSE O;  3UMH A;  3GEH A;  3U9J A;  3U2M A;  3L34 A;  2ETS A;  3NKE A;  3QTH A;  2EPL X;  4GYT A;  3FDQ A;  4AK9 A;  2FFH A;  3K6B A;  4H54 A;  4BEM J;  3LNR A;  5TJ5 E;  3ZG1 A;  3IHU A;  2A1D D;  4IWB A;  4RDA A;  2H7B A;  4ER9 A;  5KYU B;  3VAY A;  1MMG A;  2AU5 A;  4HE8 D;  2R7W A;  2YL1 A;  3B0U X;  2CNW D;  4OIO F;  1T01 A;  2XLH A;  1LI7 A;  1NU9 C;  4JKV A;  4YK5 A;  3U3B A;  1ORJ A;  3W2W A;  2R7R A;  5JRA A;  3DAG A;  3LNM B;  2GWW A;  1MNE A;  2C04 A;  4EKW A;  2R7X A;  5JUA A;  3TUL A;  2ZXP A;  4K1O A;  5F5F A;  2R03 A;  4A2N B;  3EHM A;  1Q0M A;  1ZVZ A;  3V5X A;  2LFF A;  2YWA A;  4BJ5 C;  1XWJ A;  4BJ5 A;  2H8A A;  2IXP A;  1PV3 A;  2J46 A;  1LI5 A;  1CPQ A;  1JRA A;  1V54 C;  4J7T A;  1B68 A;  3K1I C;  3K1I A;  5EHH A;  1AVO B;  1CGO A;  1Q0K A;  4NTF A;  2HSB A;  4PFO A;  2P6V A;  4Z9I A;  3V5Z A;  2V26 A;  2L6H A;  2V3C C;  2YZS A;  5CIV A;  5L3V A;  2CYD A;  1EI7 A;  2KNH A;  1YZC A;  4ZLD A;  4WAB A;  2G62 A;  4E17 A;  5DS4 A;  2A0U A;  1U6H A;  1LM3 B;  2IYL D;  2WVQ A;  1WOL A;  1L3P A;  3ZQY A;  4W8P A;  3ZWI A;  3VRC A;  1TKN A;  3DXJ F;  4JJF A;  3FVY A;  1FFT C;  1VYI A;  2Q7R A;  4NC3 A;  4BJ1 A;  1K05 A;  4C3E A;  1NG1 A;  4IGG A;  1I4Y A;  2LK4 A;  2A6E F;  1AEP A;  2P0N A;  4E7S A;  4P9F A;  4U5D E;  3HTK C;  4JZA A;  5DQZ A;  2LP4 A;  4EBB A;  3S84 A;  3Q7G A;  1Z63 A;  3N24 A;  2BL2 A;  4IAQ A;  4U5B E;  2EPN A;  2J0W A;  1RKE A;  3ITF A;  2XLM A;  1AUE A;  1KNY A;  2CDQ A;  3ABK C;  2VCB A;  3B0V C;  4D4X A;  4MW8 A;  1H9G A;  1Z23 A;  2RD9 A;  2UUI A;  2HKV A;  3AG2 C;  3B9Q A;  1BBH A;  1R4T A;  3BEH A;  3HJC A;  3CAX A;  3K7D A;  2HFI A;  2R7U A;  3QMK A;  3SXZ A;  1T6Q A;  1W2W A;  1FNT c;  4PJJ A;  3U3F A;  3NG1 A;  1G4W R;  4G0H A;  5KYU A;  5COG A;  2OQM A;  3NMI A;  1D0X A;  4G7O F;  3EG9 B;  4H4K C;  2P61 A;  3VM6 A;  4ULV A;  3C8G B;  4BJ6 A;  3I4U A;  1SMY F;  5DS6 A;  3F47 A;  3DI5 A;  4I1O B;  2A69 F;  3GEI A;  4MTG A;  3U5S A;  1OR2 A;  2XSE A;  2XS8 A;  2R02 A;  1CGM E;  1ZHY A;  3W4Y A;  1ZW3 A;  3FXH A;  1GGQ A;  1L7C A;  2PFD A;  4MQ9 F;  2YL3 A;  4JEA A;  2A6H F;  3JYH A;  3Q6N A;  5JT4 A;  2L7A A;  4NY3 A;  1ZU5 A;  2VAS A;  2ZPA A;  2AWC A;  1YYJ A;  4CS8 A;  2J7P D;  4I1M A;  4XPX A;  1PD1 A;  3ZQV A;  1FMV A;  3PCV A;  4DBR A;  2W9Y A;  4R32 A;  3DM5 A;  3LS1 A;  3NMJ A;  2L6G A;  4XEF A;  5JSL A;  3EH1 A;  1ZW2 A;  5KYY B;  1ORS C;  1OXB A;  3N2Z B;  2GDC A;  3T6J A;  4DBQ A;  2EIM C;  2VH3 A;  4JRZ A;  4JTC B;  2PNO A;  2JD3 A;  3AG1 C;  3GM2 A;  3ASN C;  2XRH A;  2CGE A;  3I5P A;  4JTA B;  4CX9 A;  5HSW A;  4XPW A;  3EFO A;  3VF0 A;  2OJE D;  1D0Z A;  3AOU A;  3LEV A;  5L0D A;  1JOG A;  3EGD A;  5T3W A;  3G4X A;  3RYL A;  3SYN A;  5L0G A;  1RCP A;  3X1O A;  1HY5 A;  2Y3D A;  2BC5 A;  1SR2 A;  1T9K A;  4G78 A;  2DB4 A;  4JCH A;  2CCY A;  2XLO A;  1GS9 A;  3KH2 A;  4UDV A;  4NQF A;  3UR3 C;  1QSP A;  1OCR C; 
#chains in the Genus database with same CATH homology
 1LS4 A;  1EA8 A;  1H7I A;  3R2P A;  1LPE A;  1EQ1 A;  1YA9 A;  1AEP A;  1NFN A;  1OR2 A;  1B68 A;  2KC3 A;  1LE2 A;  3S84 A;  1LE4 A;  1OR3 A;  1GS9 A;  1BZ4 A;  1NFO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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