4DRHB

Co-crystal structure of the ppiase domain of fkbp51, rapamycin and the frb fragment of mtor at low ph
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
95
structure length
95
Chain Sequence
AMDPEFMEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRIS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin.
pubmed doi rcsb
molecule tags Isomerase/transferase
source organism Homo sapiens
molecule keywords Peptidyl-prolyl cis-trans isomerase FKBP5
total genus 39
structure length 95
sequence length 95
chains with identical sequence E
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2012-02-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.150 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) FKBP12-rapamycin binding domain 4drhB00
1NSGB 2FAPB 2RSEB 4DRHB 2GAQA 4DRJB 3FAPB 5GPGB 1AUEA 4FAPB 4DRIB 2NPUA 1FAPB
chains in the Genus database with same CATH superfamily
4BJTA 2GWWA 1F1MA 1IZMA 2P61A 5KYYB 2PF4E 1BZ4A 2EIKC 3GEEA 3M4BA 1MMDA 4IB4A 3ZTZA 2YLGA 3FAPB 3RQFA 1T01A 2IBFA 4JRZA 1YDIA 3RW0A 2PX3A 4MTGA 1Q0KA 2QY9A 3DKAA 4O6MA 5KYXA 3FDQA 1MNEA 1T6QA 2PX0A 2ICWG 1JOGA 4XLNF 1E85A 1QZXA 3EGDA 1Q0GA 3AG2C 3GWNA 2MHRA 3AG4C 3KMIA 5TJ5E 2ZXPA 3RQGA 2YL0A 1MMNA 4AE4A 3ZQVA 4CSAC 5F5HA 4AK9A 3VF0A 2LFFA 1DOWA 2VH3A 3V5ZA 1VK5A 2XLOA 3U8VA 2LIGA 4GQHA 4ER9A 5L3VA 1E2XA 1LVKA 3ECSA 3HKKA 4NQFA 2P1AA 3HLZA 3LNRA 3SXKA 5DS6A 3H2UA 4O79A 4CS7A 5JRAA 2J9VA 3LESA 2YKZA 3PCVA 3MBGA 4C3EA 5AC5A 2IOQA 4PJNA 4Z9HA 4BJ5C 4J30B 4CJGA 2L6FA 5EGYA 2GA0A 4JVSA 4PR9A 4XQ1A 3U3FA 1O5HA 2CNWA 2CGEA 1YYXA 1RJ9B 1ZW2A 2AP3A 4LERA 4NTFA 4DBQA 1V55C 4PACA 4NTAA 1AEPA 3UGOA 3ABLC 4QI2A 2R7VA 1EKYA 3B29A 3Q7GA 3S29A 3ZG1A 3M79A 2CCYA 2Y3HA 5A6JA 1E86A 4AX2A 3KL4A 4C7OB 4JTAB 3L1MA 1MNDA 3M15A 4ZLCA 2FFHA 2L7AA 1LIHA 1G4US 2A69F 1RKCA 2L81A 1EI7A 2ZXWC 4A4AA 2Q7RA 3K66A 2WVNA 1GM5A 1WATA 2KYHA 2A68F 3TK0A 1LE2A 2J0XA 3B0UX 1HE9A 5D91A 2HFIA 1YZAA 2OJED 2OCCC 4MQ9F 2R02A 1Q0DA 4HFKB 1C02A 3T6GB 4EBBA 4CSAA 5HSWA 1LS4A 1CPQA 1M57C 1V74B 3GWLA 4JCHA 2P7VA 4LDKA 1OCRC 1RKEA 2R03A 3B0PA 2YLDA 2R7XA 4WABA 1OKKD 4U5EE 2J45A 3S90A 2HSQA 2NSGA 2R05A 4JJGA 4XPWA 1RMVA 1HMDA 1G8XA 4H4KC 2XL6A 3QTHA 3FHDA 1T5OA 1TWCA 4FWVA 1RXQA 1Z63A 2Y3DA 3LAYA 1AUEA 3GM2A 4H54A 4CX9A 3EQLF 1WTYA 3A11A 3A9CA 2Q9AA 2XL8A 2C04A 4BJ5A 2ZXRA 5EHHA 2JPUA 4BPMA 1R5ID 3U2LA 1YYJA 3AG3C 3U0CA 3RVYA 3NYJA 2CYDA 1D1AA 2IYLD 5A6AA 1M2OA 1YVIA 4ONSA 4PJMA 256BA 4AL1A 2D4UA 2A6HF 3CEXA 3DWWA 2PFDA 4N06A 2IM8A 2DI3A 4F4BA 2IXPA 2J0WA 2WZLA 3K6BA 3FAJA 3WG7C 3MYFA 1OXBA 4NC3A 2L6HA 4KNWA 4MVOA 3W4YA 4BJ1A 4PK4A 3C8GA 1ZYRF 4QDLA 1C03A 3H2VA 1NU7D 3FOOA 2GFHA 5A6BD 4JEAA 5KYWB 3L8IA 3NYMA 2YL3A 4N6HA 1O3UA 3Q6MA 4JW1A 4EIYA 4M63A 1E84A 3TULA 1SF8A 4J7YA 4U9EA 3W8IA 2PNOA 3NDBB 1FFTC 1YZCA 2VCAA 2XSEA 3F46A 3FOPA 3W8HA 4YWQA 4HEAJ 4JZAA 2X51A 3RFYA 1FTSA 3S0XA 1JMWA 4HFFB 2AVKA 5KYXB 1HY5A 4CS8A 2XLEA 1TFOB 3NMJA 3G50A 3EGDB 1TFKB 4MVMA 2D5RB 4U5DE 4Z9JA 2EPNA 1T6UA 4AE4B 1K04A 3DI5A 3S84A 1ORSC 2B0JA 1LI7A 5B1AC 1TKNA 3E9VA 3N24A 3JSEO 2NSFA 2WVQA 1M6TA 4G7OF 2EIJC 1BR4A 1QPUA 2XLVA 3AGTA 3MYIA 5BQGA 2EILC 5KYUA 3ZVRA 1NG1A 4JTDB 2HKVA 1I4YA 3EJNA 4YL0A 1OW8A 3G4ZA 3T9OA 4E18A 2R7UA 3AQBA 3DE8A 5T3TA 2I8BA 1VLTA 2AWCA 4DRHB 5JP7A 5BUOA 1ZHYA 4MVRA 2R25A 3O10A 1H6GA 3DAGA 2XLWA 4P6IC 5COFA 4CS9A 3M1CB 5COMA 1ZHWA 3EFOA 5KYNA 2LSEA 3FXHA 3FMSA 4O6YA 3DD7A 4MS2A 2R7WA 4OINF 2CNWD 4JJFA 4YK5A 3ITFA 1HMOA 1YJGA 1I5NA 3ASOC 1M2VA 2VCBA 3HJCA 2M64A 3V5XA 3SYNA 3V7OA 3X2QC 4XLPF 1J8YF 1L3PA 1NFNA 4IARA 4IGGA 3K1HA 2OKUA 3SZRA 4CDVA 1CPRA 5AGFA 4QI0A 1AVOB 1I4ZA 3EGXA 4X0RA 3TJ6A 2Y69C 4YT2A 2NUTA 3AOUA 1IW7F 2XRHA 1TWHA 2LP4A 3H65A 3IQCA 2KGOA 5DQZA 3B71A 2LCHA 1Z6AA 3LJBA 3UMHA 4I44A 1HW1A 1YA7O 2NUPB 2QTVA 3ASNC 2GDCA 1RKEB 2EPLX 3BRJA 2G3KA 3DJUB 4IAQA 1DOVA 4D4XA 3VRCA 4MVQA 4K1OA 5GPGB 4W8KA 3RIPA 4EBJA 2KJGA 1TQGA 4J7TA 3IHUA 1LKXA 3VM6A 3IEEA 1Z3IX 3I4UA 3FVYA 4KNVA 4LLEA 5CI9A 2HV6A 3EZIA 4XTKA 3ZSUA 4BG0A 4LDQA 5L0FA 1D1BA 2OG2A 3B0VC 3VAYA 4Q4ZF 2A6EF 4XWJA 2KK1A 1A0BA 2W45A 2A0BA 1YARO 4EKWA 3I5QA 1FFHA 2W4BA 4FAPB 1JRAA 2YRFA 4OIRF 2V3CC 2RSEB 2HS5A 3I5PA 1VMAA 4YT4A 3ZWIA 1LM3B 4BEMJ 4JTCB 3KYIA 4EWCA 2R7TA 1HW2A 1OW6A 1JAFA 4YJWA 1D0ZA 4I1OB 4ANJA 1D1CA 5IY5C 4DRJB 3HNIA 4PJLA 3V5YA 1BBHA 3F47A 2HJMA 2EPMX 1ZU4A 1YA9A 4WGZA 2ZPAA 3EPVA 2WB7A 1OQCA 3L0IA 3U8PA 3ABMC 4CS8C 4W8PA 1ZHXA 3RKOF 3RQEA 1LI5A 4U5GA 1OCCC 2DGJA 3B9QA 5JSLA 1SMYF 2G62A 3CQZA 3PMRA 3QMKA 3C8GD 3HNLA 3ZQYA 3SNHA 4C3DA 2QNLA 2AWYA 1VOMA 3OWTA 2UUHA 1A41A 2VB6A 3NMKA 3IQTA 3QZCA 3DZAA 3GEIA 3TOLA 5DLJA 5T1DB 5JT4A 3WODF 1G5ZA 3EG9A 3SP1A 1JPNA 4MTOA 3JCUQ 1QSPA 4NY3A 4HE8D 4N4WA 2TMVP 4O7GA 5JUAA 2XL4A 2XM4A 4RDAA 3L34A 1Z7Qc 3T6BA 1NU9C 3QW1A 3VYWA 2KSFA 3O39A 1ORYA 3SXZA 4OIPF 3GM1A 2C03A 3CZ6A 3BEHA 3K33A 4C7OA 2ZXOA 2R7QA 3TOMA 4CS9C 4E7ZA 1WWPA 3PDMP 5BQHA 1KTMA 1V54C 2UUIA 4A2NB 1LPEA 3AGUA 1S7ZA 1OCZC 4WGYA 1WOLA 3O55A 4LLCA 4PFOA 1FAPB 1ZVZA 1NSGB 4EBKA 2LK4A 2YWAA 4E17A 1PV3A 2BL2A 3KYJA 3LLKA 4YL3A 5KYUB 1U89A 4ULVA 2WZFA 1TR2A 1CGNA 2Y39A 3JYYA 1T9KA 1UFBA 2A0UA 4O6NA 4CIHA 2XXAA 4DJ9A 5EK0A 3IPMO 2VCCA 1H7IA 2HMQA 2YL1A 3JYHA 3S28A 4B6IA 2OEXA 4U9DA 3W2WA 1H9TA 3UR3C 5D92A 1G4WR 2J46A 2XS8A 3LNMB 3EFOB 1XWJA 2V26A 2CW0F 3IQ5A 4EHPA 4ULWA 4G7ZF 4E0IA 2R9RB 3C18A 1VYIA 2J7PA 1QQ3A 3DAFA 3KKBA 3QW0A 4BEJA 4P9TA 5F5FA 1M2VB 3QVZA 4RBNA 4FX5A 3RH3A 1U0BB 3NYLA 1TWAA 2YHSA 1NLXA 1QKRA 2YQYA 1QVXA 3KH2A 3QVYA 4MVUA 1N1CA 4MW3A 2R7OA 3ZIBA 4IJJA 1LS1A 3G4XA 3RYLA 2XLMA 2L9JA 3GODA 4G78A 3EGXB 3AJMA 2NUTB 4I1MA 5JVEA 2CDQA 2W4MA 2AU5A 2LFDA 3ABKC 2OJQA 1MMAA 3GORA 5F28E 1ZW3A 3GEHA 4U5FE 5K0IA 5L0CA 3R7CA 1HE1A 3JSZA 4XPYA 2Y3GA 1MQVA 2XLHA 1C17M 2J8WA 2P0NA 1OR3A 1A7DA 3MFNA 3LLIA 5BQIA 2HSBA 1RCPA 1OXKA 1WASA 1ZHZA 2Y3BA 1APCA 1EA8A 3NMIA 4OD5A 2P6VA 3LEVA 5KYWA 4JIOA 1CGME 5CI8A 2PP4A 4BJ6A 2JD3A 3KPHA 5E3CA 4MNDA 1KNYA 2M4EA 3HNJA 2Q9BA 2B0HA 3L8JA 5DVWA 2MWQA 1M56C 2JX0A 5L0DA 4IWBA 2NPUA 4J32B 4JE9A 3TQOA 3X1OA 4IAOA 1Q0MA 3ZC4A 1BDJB 3UNGC 3SXYA 1FNTc 2EPOA 3K1IC 4DVYP 1Z5ZA 5DS4A 5L0GA 4NTBA 3TD7A 1D0YA 4YL1A 4PJJA 2OOCA 4U5HA 1LE4A 4DVZA 1V4AA 3O6XA 3ZTMA 1KU2A 3NG1A 3RVZA 2XM0A 1D0XA 4Z9IA 2HMZA 2IXOA 1SZIA 2Q4FA 3T6JA 1FR0A 3N0TA 5HV9A 4RD9A 4DBRA 5L0IA 3C63A 1TWGA 2KC3A 2Q3TA 2YZSA 1ZU5A 2FGYA 1FMVA 4XEFA 5KYYA 3C62A 3AQCA 3U5SA 4DXWA 2J9UA 2J9WA 2XLDA 4GYTA 3TJ5A 2IXMA 3N2ZB 3EG9B 1U6HA 3CAXA 5A69A 4MVZA 2DYSC 2HJ3A 2VASA 5DQTA 2J9BA 4GEHA 4CBEA 2BC5A 1UG7A 3MLGA 3LEOA 3M4CA 4E7SA 3PHF2 3EHMA 1YLMA 4NCQA 1H9GA 4JC7A 2Q9CA 4Q5SF 2PBEA 1MMGA 1WN0A 1ZZPA 2H7VC 4FESA 5L0HA 3C8ZA 3WHNA 3CSKA 1W2WA 3DMDA 4K0DA 3S9OA 4XEVA 2ZD9A 3US6A 2X0CA 3C8GB 4DOZA 4G7HF 2R7SA 3UGPA 5COGA 4CJOA 4Q7CA 1OW7A 1SYQA 4U5BE 4AL0A 5A6KA 5B3SC 4G0HA 4OIOF 3W2VA 2O9XA 2H7BA 4YT8A 2BE5F 1T6IA 4JEBA 1L7CA 2A1DD 3K1IA 3OA1A 3SXMA 1BR1A 4YT5A 1JR8A 2YVKA 4KBLA 2XXAB 3AG1C 5E3AA 2FAPB 2IXNA 1A7VA 2XS1A 5L3QA 1JPJA 2ASRA 1OR2A 3OEOA 2NUPA 2G3VA 2KNHA 1NBBA 2Z15A 4LACB 4CDAA 1RJ9A 3DM5A 5CIVA 2KQ9A 1Y4CA 2QUPA 4CDYA 4MVSA 1SR2A 2WL8A 4EUKB 5JS5A 2R7RA 2EPKX 4LDRA 3JRMO 1EQ1A 1PD0A 3EZHA 1XZQA 1BR2A 4JURI 3MX3A 4PFPA 1YAUO 5AC4A 2NG1A 4E0HA 2H7OA 2LQGA 2J7PD 3U2MA 4OIQF 3POVA 2DYRC 4IRUA 4CIPA 3GANA 4YN0B 1K40A 2F22A 2YLIA 3LS0A 1ZHTA 2KW3C 3Q7LA 2E87A 1A7EA 3U9JA 4U5CE 4UDVA 2Q00A 2HV7A 2OU6A 1E83A 4BJ6C 3HNKA 4N6CA 1NFOA 2VC9A 1OKKA 3DM9B 2YEVA 3LUTB 4P9FA 3EH1A 3LS1A 4DRIB 1Q0FA 2OQMA 1VB5A 3UMKA 3ATPA 1O87A 1PCXA 3UMIA 1J8MF 1XZPA 1VLSA 2OEVA 5E2QA 2QLAA 2YL7A 3EHNA 3T4RA 5B3IA 2HZ8A 4D4NA 3U3BA 1Y6DA 1GGQA 1GQAA 1S05A 2ETSA 3JT1A 5T3WA 3DJNB 1GS9A 4KC9A 4ZLDA 1NZEA 3E70C 3Q6NA 3ZDLA 2WZGA 5DS5A 1FMWA 3S27A 1OCOC 3NRHA 3IQ6A 5B1BC 5E33A 4MTFA 2WVOA 2H8AA 4XEKA 1VTMP 4C3BA 1K05A 5L0JA 2QE9A 1ORJA 2GAQA 3C7JA 3R2PA 3DE9A 4K7BA 4XPXA 5FZTA 3J06A 1PD1A 4OD4A 5JLIA 2MYSA 4MW8A 3U9MA 1CGOA 2LD6A 3RF3A 3SEOA 3GM3A 4L6RA 3JZ0A 3HTKC 3K7DA 1WGWA 5A6BA 2DB4A 5FCLA 1VYKA 2EIMC 3JTLO 2RD9A 3EH2A 3NKEA 3JRTA 2I15A 1Z23A 2EINC 2HUJA 4WJ0A 1B68A 4I3MA 4JCZA 4KI2A 1R4TA 3WAQA 4R32A 3NKDA 2L6GA 3DXJF 1QLEC 2W9YA 1ST6A 4JKVA
chains in the Genus database with same CATH topology
1NSGB 2FAPB 2RSEB 4DRHB 2GAQA 4DRJB 3FAPB 5GPGB 1AUEA 4FAPB 4DRIB 2NPUA 1FAPB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NSG B;  2FAP B;  2RSE B;  4DRH B;  2GAQ A;  4DRJ B;  3FAP B;  5GPG B;  1AUE A;  4FAP B;  4DRI B;  2NPU A;  1FAP B; 
#chains in the Genus database with same CATH topology
 4BJT A;  2GWW A;  1F1M A;  1IZM A;  2P61 A;  5KYY B;  2PF4 E;  1BZ4 A;  2EIK C;  3GEE A;  3M4B A;  1MMD A;  4IB4 A;  3ZTZ A;  2YLG A;  3FAP B;  3RQF A;  1T01 A;  2IBF A;  4JRZ A;  1YDI A;  3RW0 A;  2PX3 A;  4MTG A;  1Q0K A;  2QY9 A;  3DKA A;  4O6M A;  5KYX A;  3FDQ A;  1MNE A;  1T6Q A;  2PX0 A;  2ICW G;  1JOG A;  4XLN F;  1E85 A;  1QZX A;  3EGD A;  1Q0G A;  3AG2 C;  3GWN A;  2MHR A;  3AG4 C;  3KMI A;  5TJ5 E;  2ZXP A;  3RQG A;  2YL0 A;  1MMN A;  4AE4 A;  3ZQV A;  4CSA C;  5F5H A;  4AK9 A;  3VF0 A;  2LFF A;  1DOW A;  2VH3 A;  3V5Z A;  1VK5 A;  2XLO A;  3U8V A;  2LIG A;  4GQH A;  4ER9 A;  5L3V A;  1E2X A;  1LVK A;  3ECS A;  3HKK A;  4NQF A;  2P1A A;  3HLZ A;  3LNR A;  3SXK A;  5DS6 A;  3H2U A;  4O79 A;  4CS7 A;  5JRA A;  2J9V A;  3LES A;  2YKZ A;  3PCV A;  3MBG A;  4C3E A;  5AC5 A;  2IOQ A;  4PJN A;  4Z9H A;  4BJ5 C;  4J30 B;  4CJG A;  2L6F A;  5EGY A;  2GA0 A;  4JVS A;  4PR9 A;  4XQ1 A;  3U3F A;  1O5H A;  2CNW A;  2CGE A;  1YYX A;  1RJ9 B;  1ZW2 A;  2AP3 A;  4LER A;  4NTF A;  4DBQ A;  1V55 C;  4PAC A;  4NTA A;  1AEP A;  3UGO A;  3ABL C;  4QI2 A;  2R7V A;  1EKY A;  3B29 A;  3Q7G A;  3S29 A;  3ZG1 A;  3M79 A;  2CCY A;  2Y3H A;  5A6J A;  1E86 A;  4AX2 A;  3KL4 A;  4C7O B;  4JTA B;  3L1M A;  1MND A;  3M15 A;  4ZLC A;  2FFH A;  2L7A A;  1LIH A;  1G4U S;  2A69 F;  1RKC A;  2L81 A;  1EI7 A;  2ZXW C;  4A4A A;  2Q7R A;  3K66 A;  2WVN A;  1GM5 A;  1WAT A;  2KYH A;  2A68 F;  3TK0 A;  1LE2 A;  2J0X A;  3B0U X;  1HE9 A;  5D91 A;  2HFI A;  1YZA A;  2OJE D;  2OCC C;  4MQ9 F;  2R02 A;  1Q0D A;  4HFK B;  1C02 A;  3T6G B;  4EBB A;  4CSA A;  5HSW A;  1LS4 A;  1CPQ A;  1M57 C;  1V74 B;  3GWL A;  4JCH A;  2P7V A;  4LDK A;  1OCR C;  1RKE A;  2R03 A;  3B0P A;  2YLD A;  2R7X A;  4WAB A;  1OKK D;  4U5E E;  2J45 A;  3S90 A;  2HSQ A;  2NSG A;  2R05 A;  4JJG A;  4XPW A;  1RMV A;  1HMD A;  1G8X A;  4H4K C;  2XL6 A;  3QTH A;  3FHD A;  1T5O A;  1TWC A;  4FWV A;  1RXQ A;  1Z63 A;  2Y3D A;  3LAY A;  1AUE A;  3GM2 A;  4H54 A;  4CX9 A;  3EQL F;  1WTY A;  3A11 A;  3A9C A;  2Q9A A;  2XL8 A;  2C04 A;  4BJ5 A;  2ZXR A;  5EHH A;  2JPU A;  4BPM A;  1R5I D;  3U2L A;  1YYJ A;  3AG3 C;  3U0C A;  3RVY A;  3NYJ A;  2CYD A;  1D1A A;  2IYL D;  5A6A A;  1M2O A;  1YVI A;  4ONS A;  4PJM A;  256B A;  4AL1 A;  2D4U A;  2A6H F;  3CEX A;  3DWW A;  2PFD A;  4N06 A;  2IM8 A;  2DI3 A;  4F4B A;  2IXP A;  2J0W A;  2WZL A;  3K6B A;  3FAJ A;  3WG7 C;  3MYF A;  1OXB A;  4NC3 A;  2L6H A;  4KNW A;  4MVO A;  3W4Y A;  4BJ1 A;  4PK4 A;  3C8G A;  1ZYR F;  4QDL A;  1C03 A;  3H2V A;  1NU7 D;  3FOO A;  2GFH A;  5A6B D;  4JEA A;  5KYW B;  3L8I A;  3NYM A;  2YL3 A;  4N6H A;  1O3U A;  3Q6M A;  4JW1 A;  4EIY A;  4M63 A;  1E84 A;  3TUL A;  1SF8 A;  4J7Y A;  4U9E A;  3W8I A;  2PNO A;  3NDB B;  1FFT C;  1YZC A;  2VCA A;  2XSE A;  3F46 A;  3FOP A;  3W8H A;  4YWQ A;  4HEA J;  4JZA A;  2X51 A;  3RFY A;  1FTS A;  3S0X A;  1JMW A;  4HFF B;  2AVK A;  5KYX B;  1HY5 A;  4CS8 A;  2XLE A;  1TFO B;  3NMJ A;  3G50 A;  3EGD B;  1TFK B;  4MVM A;  2D5R B;  4U5D E;  4Z9J A;  2EPN A;  1T6U A;  4AE4 B;  1K04 A;  3DI5 A;  3S84 A;  1ORS C;  2B0J A;  1LI7 A;  5B1A C;  1TKN A;  3E9V A;  3N24 A;  3JSE O;  2NSF A;  2WVQ A;  1M6T A;  4G7O F;  2EIJ C;  1BR4 A;  1QPU A;  2XLV A;  3AGT A;  3MYI A;  5BQG A;  2EIL C;  5KYU A;  3ZVR A;  1NG1 A;  4JTD B;  2HKV A;  1I4Y A;  3EJN A;  4YL0 A;  1OW8 A;  3G4Z A;  3T9O A;  4E18 A;  2R7U A;  3AQB A;  3DE8 A;  5T3T A;  2I8B A;  1VLT A;  2AWC A;  4DRH B;  5JP7 A;  5BUO A;  1ZHY A;  4MVR A;  2R25 A;  3O10 A;  1H6G A;  3DAG A;  2XLW A;  4P6I C;  5COF A;  4CS9 A;  3M1C B;  5COM A;  1ZHW A;  3EFO A;  5KYN A;  2LSE A;  3FXH A;  3FMS A;  4O6Y A;  3DD7 A;  4MS2 A;  2R7W A;  4OIN F;  2CNW D;  4JJF A;  4YK5 A;  3ITF A;  1HMO A;  1YJG A;  1I5N A;  3ASO C;  1M2V A;  2VCB A;  3HJC A;  2M64 A;  3V5X A;  3SYN A;  3V7O A;  3X2Q C;  4XLP F;  1J8Y F;  1L3P A;  1NFN A;  4IAR A;  4IGG A;  3K1H A;  2OKU A;  3SZR A;  4CDV A;  1CPR A;  5AGF A;  4QI0 A;  1AVO B;  1I4Z A;  3EGX A;  4X0R A;  3TJ6 A;  2Y69 C;  4YT2 A;  2NUT A;  3AOU A;  1IW7 F;  2XRH A;  1TWH A;  2LP4 A;  3H65 A;  3IQC A;  2KGO A;  5DQZ A;  3B71 A;  2LCH A;  1Z6A A;  3LJB A;  3UMH A;  4I44 A;  1HW1 A;  1YA7 O;  2NUP B;  2QTV A;  3ASN C;  2GDC A;  1RKE B;  2EPL X;  3BRJ A;  2G3K A;  3DJU B;  4IAQ A;  1DOV A;  4D4X A;  3VRC A;  4MVQ A;  4K1O A;  5GPG B;  4W8K A;  3RIP A;  4EBJ A;  2KJG A;  1TQG A;  4J7T A;  3IHU A;  1LKX A;  3VM6 A;  3IEE A;  1Z3I X;  3I4U A;  3FVY A;  4KNV A;  4LLE A;  5CI9 A;  2HV6 A;  3EZI A;  4XTK A;  3ZSU A;  4BG0 A;  4LDQ A;  5L0F A;  1D1B A;  2OG2 A;  3B0V C;  3VAY A;  4Q4Z F;  2A6E F;  4XWJ A;  2KK1 A;  1A0B A;  2W45 A;  2A0B A;  1YAR O;  4EKW A;  3I5Q A;  1FFH A;  2W4B A;  4FAP B;  1JRA A;  2YRF A;  4OIR F;  2V3C C;  2RSE B;  2HS5 A;  3I5P A;  1VMA A;  4YT4 A;  3ZWI A;  1LM3 B;  4BEM J;  4JTC B;  3KYI A;  4EWC A;  2R7T A;  1HW2 A;  1OW6 A;  1JAF A;  4YJW A;  1D0Z A;  4I1O B;  4ANJ A;  1D1C A;  5IY5 C;  4DRJ B;  3HNI A;  4PJL A;  3V5Y A;  1BBH A;  3F47 A;  2HJM A;  2EPM X;  1ZU4 A;  1YA9 A;  4WGZ A;  2ZPA A;  3EPV A;  2WB7 A;  1OQC A;  3L0I A;  3U8P A;  3ABM C;  4CS8 C;  4W8P A;  1ZHX A;  3RKO F;  3RQE A;  1LI5 A;  4U5G A;  1OCC C;  2DGJ A;  3B9Q A;  5JSL A;  1SMY F;  2G62 A;  3CQZ A;  3PMR A;  3QMK A;  3C8G D;  3HNL A;  3ZQY A;  3SNH A;  4C3D A;  2QNL A;  2AWY A;  1VOM A;  3OWT A;  2UUH A;  1A41 A;  2VB6 A;  3NMK A;  3IQT A;  3QZC A;  3DZA A;  3GEI A;  3TOL A;  5DLJ A;  5T1D B;  5JT4 A;  3WOD F;  1G5Z A;  3EG9 A;  3SP1 A;  1JPN A;  4MTO A;  3JCU Q;  1QSP A;  4NY3 A;  4HE8 D;  4N4W A;  2TMV P;  4O7G A;  5JUA A;  2XL4 A;  2XM4 A;  4RDA A;  3L34 A;  1Z7Q c;  3T6B A;  1NU9 C;  3QW1 A;  3VYW A;  2KSF A;  3O39 A;  1ORY A;  3SXZ A;  4OIP F;  3GM1 A;  2C03 A;  3CZ6 A;  3BEH A;  3K33 A;  4C7O A;  2ZXO A;  2R7Q A;  3TOM A;  4CS9 C;  4E7Z A;  1WWP A;  3PDM P;  5BQH A;  1KTM A;  1V54 C;  2UUI A;  4A2N B;  1LPE A;  3AGU A;  1S7Z A;  1OCZ C;  4WGY A;  1WOL A;  3O55 A;  4LLC A;  4PFO A;  1FAP B;  1ZVZ A;  1NSG B;  4EBK A;  2LK4 A;  2YWA A;  4E17 A;  1PV3 A;  2BL2 A;  3KYJ A;  3LLK A;  4YL3 A;  5KYU B;  1U89 A;  4ULV A;  2WZF A;  1TR2 A;  1CGN A;  2Y39 A;  3JYY A;  1T9K A;  1UFB A;  2A0U A;  4O6N A;  4CIH A;  2XXA A;  4DJ9 A;  5EK0 A;  3IPM O;  2VCC A;  1H7I A;  2HMQ A;  2YL1 A;  3JYH A;  3S28 A;  4B6I A;  2OEX A;  4U9D A;  3W2W A;  1H9T A;  3UR3 C;  5D92 A;  1G4W R;  2J46 A;  2XS8 A;  3LNM B;  3EFO B;  1XWJ A;  2V26 A;  2CW0 F;  3IQ5 A;  4EHP A;  4ULW A;  4G7Z F;  4E0I A;  2R9R B;  3C18 A;  1VYI A;  2J7P A;  1QQ3 A;  3DAF A;  3KKB A;  3QW0 A;  4BEJ A;  4P9T A;  5F5F A;  1M2V B;  3QVZ A;  4RBN A;  4FX5 A;  3RH3 A;  1U0B B;  3NYL A;  1TWA A;  2YHS A;  1NLX A;  1QKR A;  2YQY A;  1QVX A;  3KH2 A;  3QVY A;  4MVU A;  1N1C A;  4MW3 A;  2R7O A;  3ZIB A;  4IJJ A;  1LS1 A;  3G4X A;  3RYL A;  2XLM A;  2L9J A;  3GOD A;  4G78 A;  3EGX B;  3AJM A;  2NUT B;  4I1M A;  5JVE A;  2CDQ A;  2W4M A;  2AU5 A;  2LFD A;  3ABK C;  2OJQ A;  1MMA A;  3GOR A;  5F28 E;  1ZW3 A;  3GEH A;  4U5F E;  5K0I A;  5L0C A;  3R7C A;  1HE1 A;  3JSZ A;  4XPY A;  2Y3G A;  1MQV A;  2XLH A;  1C17 M;  2J8W A;  2P0N A;  1OR3 A;  1A7D A;  3MFN A;  3LLI A;  5BQI A;  2HSB A;  1RCP A;  1OXK A;  1WAS A;  1ZHZ A;  2Y3B A;  1APC A;  1EA8 A;  3NMI A;  4OD5 A;  2P6V A;  3LEV A;  5KYW A;  4JIO A;  1CGM E;  5CI8 A;  2PP4 A;  4BJ6 A;  2JD3 A;  3KPH A;  5E3C A;  4MND A;  1KNY A;  2M4E A;  3HNJ A;  2Q9B A;  2B0H A;  3L8J A;  5DVW A;  2MWQ A;  1M56 C;  2JX0 A;  5L0D A;  4IWB A;  2NPU A;  4J32 B;  4JE9 A;  3TQO A;  3X1O A;  4IAO A;  1Q0M A;  3ZC4 A;  1BDJ B;  3UNG C;  3SXY A;  1FNT c;  2EPO A;  3K1I C;  4DVY P;  1Z5Z A;  5DS4 A;  5L0G A;  4NTB A;  3TD7 A;  1D0Y A;  4YL1 A;  4PJJ A;  2OOC A;  4U5H A;  1LE4 A;  4DVZ A;  1V4A A;  3O6X A;  3ZTM A;  1KU2 A;  3NG1 A;  3RVZ A;  2XM0 A;  1D0X A;  4Z9I A;  2HMZ A;  2IXO A;  1SZI A;  2Q4F A;  3T6J A;  1FR0 A;  3N0T A;  5HV9 A;  4RD9 A;  4DBR A;  5L0I A;  3C63 A;  1TWG A;  2KC3 A;  2Q3T A;  2YZS A;  1ZU5 A;  2FGY A;  1FMV A;  4XEF A;  5KYY A;  3C62 A;  3AQC A;  3U5S A;  4DXW A;  2J9U A;  2J9W A;  2XLD A;  4GYT A;  3TJ5 A;  2IXM A;  3N2Z B;  3EG9 B;  1U6H A;  3CAX A;  5A69 A;  4MVZ A;  2DYS C;  2HJ3 A;  2VAS A;  5DQT A;  2J9B A;  4GEH A;  4CBE A;  2BC5 A;  1UG7 A;  3MLG A;  3LEO A;  3M4C A;  4E7S A;  3PHF 2;  3EHM A;  1YLM A;  4NCQ A;  1H9G A;  4JC7 A;  2Q9C A;  4Q5S F;  2PBE A;  1MMG A;  1WN0 A;  1ZZP A;  2H7V C;  4FES A;  5L0H A;  3C8Z A;  3WHN A;  3CSK A;  1W2W A;  3DMD A;  4K0D A;  3S9O A;  4XEV A;  2ZD9 A;  3US6 A;  2X0C A;  3C8G B;  4DOZ A;  4G7H F;  2R7S A;  3UGP A;  5COG A;  4CJO A;  4Q7C A;  1OW7 A;  1SYQ A;  4U5B E;  4AL0 A;  5A6K A;  5B3S C;  4G0H A;  4OIO F;  3W2V A;  2O9X A;  2H7B A;  4YT8 A;  2BE5 F;  1T6I A;  4JEB A;  1L7C A;  2A1D D;  3K1I A;  3OA1 A;  3SXM A;  1BR1 A;  4YT5 A;  1JR8 A;  2YVK A;  4KBL A;  2XXA B;  3AG1 C;  5E3A A;  2FAP B;  2IXN A;  1A7V A;  2XS1 A;  5L3Q A;  1JPJ A;  2ASR A;  1OR2 A;  3OEO A;  2NUP A;  2G3V A;  2KNH A;  1NBB A;  2Z15 A;  4LAC B;  4CDA A;  1RJ9 A;  3DM5 A;  5CIV A;  2KQ9 A;  1Y4C A;  2QUP A;  4CDY A;  4MVS A;  1SR2 A;  2WL8 A;  4EUK B;  5JS5 A;  2R7R A;  2EPK X;  4LDR A;  3JRM O;  1EQ1 A;  1PD0 A;  3EZH A;  1XZQ A;  1BR2 A;  4JUR I;  3MX3 A;  4PFP A;  1YAU O;  5AC4 A;  2NG1 A;  4E0H A;  2H7O A;  2LQG A;  2J7P D;  3U2M A;  4OIQ F;  3POV A;  2DYR C;  4IRU A;  4CIP A;  3GAN A;  4YN0 B;  1K40 A;  2F22 A;  2YLI A;  3LS0 A;  1ZHT A;  2KW3 C;  3Q7L A;  2E87 A;  1A7E A;  3U9J A;  4U5C E;  4UDV A;  2Q00 A;  2HV7 A;  2OU6 A;  1E83 A;  4BJ6 C;  3HNK A;  4N6C A;  1NFO A;  2VC9 A;  1OKK A;  3DM9 B;  2YEV A;  3LUT B;  4P9F A;  3EH1 A;  3LS1 A;  4DRI B;  1Q0F A;  2OQM A;  1VB5 A;  3UMK A;  3ATP A;  1O87 A;  1PCX A;  3UMI A;  1J8M F;  1XZP A;  1VLS A;  2OEV A;  5E2Q A;  2QLA A;  2YL7 A;  3EHN A;  3T4R A;  5B3I A;  2HZ8 A;  4D4N A;  3U3B A;  1Y6D A;  1GGQ A;  1GQA A;  1S05 A;  2ETS A;  3JT1 A;  5T3W A;  3DJN B;  1GS9 A;  4KC9 A;  4ZLD A;  1NZE A;  3E70 C;  3Q6N A;  3ZDL A;  2WZG A;  5DS5 A;  1FMW A;  3S27 A;  1OCO C;  3NRH A;  3IQ6 A;  5B1B C;  5E33 A;  4MTF A;  2WVO A;  2H8A A;  4XEK A;  1VTM P;  4C3B A;  1K05 A;  5L0J A;  2QE9 A;  1ORJ A;  2GAQ A;  3C7J A;  3R2P A;  3DE9 A;  4K7B A;  4XPX A;  5FZT A;  3J06 A;  1PD1 A;  4OD4 A;  5JLI A;  2MYS A;  4MW8 A;  3U9M A;  1CGO A;  2LD6 A;  3RF3 A;  3SEO A;  3GM3 A;  4L6R A;  3JZ0 A;  3HTK C;  3K7D A;  1WGW A;  5A6B A;  2DB4 A;  5FCL A;  1VYK A;  2EIM C;  3JTL O;  2RD9 A;  3EH2 A;  3NKE A;  3JRT A;  2I15 A;  1Z23 A;  2EIN C;  2HUJ A;  4WJ0 A;  1B68 A;  4I3M A;  4JCZ A;  4KI2 A;  1R4T A;  3WAQ A;  4R32 A;  3NKD A;  2L6G A;  3DXJ F;  1QLE C;  2W9Y A;  1ST6 A;  4JKV A; 
#chains in the Genus database with same CATH homology
 1NSG B;  2FAP B;  2RSE B;  4DRH B;  2GAQ A;  4DRJ B;  3FAP B;  5GPG B;  1AUE A;  4FAP B;  4DRI B;  2NPU A;  1FAP B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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