2NPUA

The solution structure of the rapamycin-binding domain of mtor (frb)
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
101
structure length
101
Chain Sequence
b'MELIRVPILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQ'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords FKBP12-rapamycin complex-associated protein
publication title Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 28
structure length 101
sequence length 101
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2006-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08771 FRB_dom FKBP12-rapamycin binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.150 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) FKBP12-rapamycin binding domain 2npuA00
2GAQA 2RSEB 5GPGB 2NPUA 3FAPB 2FAPB 4DRIB 4FAPB 1FAPB 4DRHB 1AUEA 1NSGB 4DRJB
chains in the Genus database with same CATH superfamily
5L0DA 3C18A 3IQ6A 3J06A 2KGOA 3U5SA 4NC3A 2WZLA 4CIPA 2MYSA 2YHSA 3I4UA 3E70C 3ABLC 4XEFA 1MMGA 1Y4CA 4N06A 2HMZA 5JP7A 2CNWD 1SZIA 2ZPAA 1LI7A 3C62A 2J0WA 3GEEA 4X0RA 2Y3DA 3N24A 2X0CA 1GGQA 2YL3A 1G4US 1Z6AA 4IARA 4BJ5C 2J9WA 3JSEO 3LS1A 3WG7C 1Z5ZA 3V7OA 1Q0GA 1YYJA 2OEXA 1CGNA 1HMOA 1TFKB 3EG9A 2OEVA 3HNIA 3K7DA 2LD6A 3EGDA 3CEXA 1RJ9B 4YK5A 3TJ5A 1M6TA 4U5BE 1TR2A 4LACB 4MTFA 3I5PA 4JJFA 4ZLDA 3K33A 2R25A 1KU2A 4CBEA 4JTAB 1NSGB 1RKCA 4BEMJ 2KC3A 3JTLO 3EGXA 4JCHA 4IWBA 2XLMA 2R7OA 1NBBA 4Z9JA 2B0HA 1EA8A 1JR8A 3HKKA 5K0IA 5KYXA 1TWHA 1C03A 3EG9B 4FESA 3US6A 1D0YA 2YZSA 4U9EA 3JCUQ 3KPHA 4Q5SF 1HW1A 2OG2A 2EPKX 3DM5A 3NKEA 2P1AA 3C8ZA 3GM3A 2QUPA 1CPRA 3JSZA 1VYKA 2KNHA 2W9YA 4W8KA 3EGXB 3S9OA 2ZXWC 4C7OB 3K1HA 1EI7A 1IZMA 2L6GA 3RYLA 4E7ZA 5KYXB 3ASNC 4B6IA 3B9QA 4YJWA 1U89A 5EHHA 4PACA 2R7RA 4MNDA 3HTKC 3EPVA 4YWQA 3IPMO 1WASA 3LUTB 4YT4A 2HZ8A 5BQIA 3RF3A 3ZDLA 1OW7A 1ZHZA 2HSQA 4G78A 4JJGA 3T9OA 4EUKB 3S0XA 2XXAA 3TJ6A 3U3FA 1ORYA 2R9RB 2AWCA 4YL0A 1ORSC 5CI9A 2YKZA 2J9UA 4MTGA 3ZIBA 4AE4B 1QPUA 5E3CA 3R2PA 4H4KC 3RVYA 2P7VA 2P6VA 4JEAA 2HJ3A 2W45A 3HNLA 1ZYRF 2Q9CA 2Y3HA 2YRFA 2ETSA 3NYMA 3SYNA 1ZVZA 4H54A 3AGTA 4O7GA 4F4BA 1MMDA 2XXAB 5GPGB 1APCA 1U0BB 3B0PA 4G0HA 5CI8A 4K7BA 1KNYA 1RKEA 3JYYA 2WVNA 3VF0A 4PJJA 1MMAA 1VOMA 2G3KA 1YDIA 2MHRA 3K1IA 1T5OA 4EBBA 1XZPA 1LPEA 3DKAA 3HNJA 1VLTA 3E9VA 4HE8D 4JRZA 4K0DA 3W8IA 3W8HA 3ASOC 1Z7Qc 2Y3GA 3U2LA 4CJGA 1UG7A 4CIHA 5JVEA 4WGZA 5D92A 4Q4ZF 1RKEB 3GODA 4U5GA 2XM4A 1K05A 3N2ZB 2HMQA 3AG2C 2R05A 1YZAA 2PFDA 5IY5C 5DS5A 2XS8A 4BEJA 1N1CA 5A6BA 2P0NA 4JTCB 4IRUA 4MVUA 1AVOB 1Q0DA 2XLOA 3JRMO 4XPYA 3SXKA 2HV7A 2J9VA 4EWCA 3EHMA 1JAFA 1CGME 1GQAA 1LE2A 1VLSA 3FVYA 4U5DE 2H7BA 2Q00A 1ZHWA 2F22A 1TQGA 4DOZA 2EPLX 2EPNA 2CYDA 3NRHA 2A6EF 2PF4E 3LLIA 1K40A 4R32A 2EILC 2J46A 3M1CB 4DXWA 3FAJA 2PX0A 2YEVA 3BEHA 1Z3IX 1OXBA 3LJBA 4JIOA 3B0VC 3IEEA 3VYWA 4PFPA 1HE1A 5F5FA 1FAPB 1D0ZA 3AG1C 2LSEA 4D4NA 4U5EE 2CGEA 3W2VA 1R4TA 2LFDA 3GANA 2NSFA 2PX3A 1PD0A 2H7OA 1ZZPA 4CSAA 3W4YA 1TWGA 3FDQA 1VK5A 5JSLA 1OCZC 3MYFA 3Q7GA 4O79A 3NG1A 3OA1A 1VMAA 3K1IC 3OEOA 3L8JA 4U5HA 4A2NB 1E83A 4RDAA 3CQZA 3ZSUA 5CIVA 4HEAJ 2VASA 3W2WA 5DQZA 1NZEA 5JRAA 5L3QA 3NMJA 1FFTC 4RBNA 1LVKA 1LS4A 2BC5A 3OWTA 4DRIB 4E0HA 4A4AA 1HW2A 3K66A 2PP4A 2WZGA 1H9TA 2A0UA 2J7PD 1U6HA 2UUIA 3AJMA 1G4WR 2NG1A 1YA9A 3MLGA 2DYSC 4BPMA 3M4CA 3TD7A 3H65A 1C17M 3U9JA 5A6JA 1RJ9A 3CSKA 1Z23A 4MVOA 1E85A 4BJTA 4ULWA 4MVZA 4DBRA 3LLKA 2E87A 4JE9A 2C03A 3LEVA 2Q3TA 1WATA 1IW7F 3O10A 1T9KA 3DMDA 3PCVA 2V3CC 4CDAA 1LE4A 2HV6A 2YLIA 1S7ZA 1ST6A 2FFHA 4ZLCA 3ABKC 3FHDA 3PMRA 1TFOB 4JTDB 5FZTA 3RQGA 2QY9A 4JCZA 1R5ID 1FNTc 1TWAA 2XM0A 1BZ4A 4JZAA 5D91A 5KYYB 3U2MA 4M63A 2M64A 2C04A 2DYRC 4U5CE 1T6QA 2BE5F 2UUHA 1D0XA 1ZHYA 2ZXRA 1NFNA 3Q6MA 2GWWA 1BR4A 3QZCA 4ONSA 4CSAC 4C7OA 5KYWA 1LKXA 1Q0MA 1OR2A 1OR3A 2YWAA 4ULVA 4WGYA 1T6UA 3PDMP 4I1OB 3EFOA 4XLPF 3NMIA 4MVQA 5BUOA 2D4UA 1FMVA 1G8XA 1L3PA 3QMKA 1WWPA 1VB5A 4HFKB 4J32B 3DJUB 4J30B 4PJMA 4XTKA 3RIPA 5BQHA 2HJMA 3ITFA 3MX3A 4C3EA 4EHPA 4JKVA 2J7PA 4Q7CA 4Z9HA 3AOUA 3QW0A 5DVWA 5KYWB 4EBKA 1ZU4A 2QLAA 1LS1A 4DBQA 2AP3A 4OIOF 3PHF2 3RH3A 3EFOB 1W2WA 2FAPB 4D4XA 2KYHA 3NMKA 4XEVA 1HMDA 2CNWA 3N0TA 3AQBA 3ZTZA 2OOCA 2LFFA 3IQCA 4P6IC 3U8PA 2HS5A 3V5YA 1WGWA 4IAQA 2PNOA 5JT4A 1YYXA 2G3VA 3QTHA 4KBLA 1VTMP 3GWNA 4CDYA 2NSGA 1NG1A 1WOLA 3LNMB 5L3VA 1F1MA 3V5ZA 1H6GA 1SMYF 2D5RB 2LQGA 2ZXOA 4I1MA 1FFHA 2J0XA 1YAUO 2L9JA 3GEHA 4YL3A 3UR3C 1OKKD 3UMIA 3T6GB 1CGOA 3A11A 2RSEB 3HJCA 4P9TA 4PK4A 1WTYA 2VCBA 3X2QC 4EBJA 2R7WA 5KYYA 2ASRA 3T6BA 1LM3B 5COFA 4NTBA 2CCYA 4NY3A 2VC9A 4XEKA 3DJNB 4AX2A 3IQ5A 4NTAA 5HV9A 3DE8A 3O6XA 3U0CA 2LIGA 5JLIA 1V54C 2YL7A 3DAFA 1YJGA 4DRJB 1YZCA 2XS1A 5L0JA 5T3TA 2XLHA 4ANJA 1T6IA 2YLDA 1O3UA 3R7CA 4C3DA 2Q9AA 2XLVA 1QLEC 4U5FE 2B0JA 4WABA 3TOLA 5F5HA 4OINF 3VM6A 4GEHA 4DVZA 3NKDA 1MNDA 1SYQA 1XWJA 3DAGA 2BL2A 3WHNA 4P9FA 2X51A 3DWWA 3DXJF 1NFOA 3A9CA 5A69A 5HSWA 1O87A 3EZIA 3HNKA 3EJNA 4CS9A 5AC5A 3TQOA 4MVSA 1TKNA 4U9DA 4ER9A 3JT1A 3DE9A 3AG4C 1NU7D 3U8VA 4CDVA 3B71A 1D1BA 4O6YA 5KYNA 4EIYA 4N4WA 3L1MA 1H9GA 1PV3A 3QW1A 4UDVA 4MQ9F 4XWJA 4N6CA 1Y6DA 1YVIA 4FWVA 1A7DA 4JEBA 4KNVA 1DOWA 4KC9A 3EH2A 3DM9B 2Q4FA 5AGFA 2PBEA 4C3BA 4N6HA 3DZAA 3SZRA 1V55C 2LK4A 2R03A 2XSEA 2NUTA 4MVMA 5L0IA 2OJQA 2OKUA 2AWYA 4OIRF 3LS0A 3RKOF 3ZG1A 2XL8A 3L34A 2V26A 4EKWA 2JD3A 2LP4A 2WVQA 3SEOA 3JYHA 1GS9A 3C8GD 1QVXA 5B1BC 2R7SA 2ZD9A 4YN0B 4YL1A 3LESA 2YLGA 4LDRA 3V5XA 3M4BA 4YT5A 2NUTB 4BJ6A 1RMVA 3FMSA 3NDBB 1SR2A 2IOQA 3K6BA 1QSPA 2Q9BA 2VB6A 5T1DB 1MQVA 1S05A 2DB4A 2OCCC 3JZ0A 2QTVA 2XL4A 2WL8A 2XLDA 1M57C 2R02A 4RD9A 5JS5A 5L0GA 3CAXA 3M79A 3RQEA 4CS9C 2VH3A 2XLEA 2NUPA 2RD9A 3QVYA 3G4XA 4JURI 1DOVA 4NQFA 3S90A 1YARO 3T6JA 256BA 2OJED 1G5ZA 2WB7A 3ABMC 1ZW3A 1T01A 4I3MA 4J7TA 5A6KA 2A6HF 4FAPB 1MNEA 1ZHTA 3KYIA 4DJ9A 3GEIA 3FXHA 4E17A 2QE9A 5E2QA 2H7VC 3AG3C 1ZHXA 4DVYP 2QNLA 2NUPB 2Y3BA 3WODF 1JPNA 3MFNA 2R7QA 2YQYA 1A7EA 2HFIA 2A69F 4OD5A 4QDLA 5B3SC 1EKYA 3B29A 1BBHA 2YL1A 1YA7O 3NYLA 5E3AA 4FX5A 3C8GA 3LEOA 4LLCA 3KMIA 2KW3C 2WVOA 4IB4A 4CS7A 3L0IA 2XLWA 4XLNF 4IJJA 4AL0A 1C02A 4AK9A 1SF8A 4OD4A 4BJ1A 2Z15A 3JRTA 3UMKA 2R7XA 4J7YA 3LAYA 4JVSA 1K04A 2GAQA 3LNRA 1JRAA 4BJ6C 5E33A 1OW8A 2IM8A 3C8GB 2EPMX 3L8IA 3AQCA 3RFYA 1MMNA 3H2UA 5DQTA 3C63A 3U9MA 5JUAA 3C7JA 5TJ5E 1JPJA 4MW3A 4NCQA 3M15A 2L6FA 2W4MA 3Q6NA 1PCXA 4IAOA 1RCPA 3U3BA 1E86A 2MWQA 2FGYA 3EQLF 1QKRA 1ZU5A 2O9XA 4G7HF 4CS8A 3EGDB 2M4EA 4LERA 2KSFA 2EIKC 1BR1A 4WJ0A 1TWCA 1A41A 5AC4A 1OW6A 1E2XA 4KI2A 2W4BA 4OIQF 1BR2A 2Y39A 3BRJA 4PJNA 3RW0A 1Z63A 4W8PA 3S84A 4E18A 2EIJC 2J45A 1J8MF 1D1CA 1KTMA 3EZHA 4PR9A 2P61A 4MVRA 5FCLA 3GWLA 4QI2A 3F46A 1L7CA 2JX0A 2GFHA 4LLEA 4LDKA 2XL6A 2JPUA 5A6BD 2IBFA 4XPWA 3ECSA 1FTSA 2G62A 1I4ZA 3KKBA 2J8WA 2IXPA 1M2VA 3S28A 5L0FA 2EIMC 2A68F 1NLXA 2HSBA 2ZXPA 2IXOA 3CZ6A 5DS4A 1V4AA 1I4YA 3KH2A 1H7IA 3RQFA 2EPOA 2AVKA 1AUEA 3G4ZA 1GM5A 4E0IA 4CX9A 3X1OA 3VAYA 2L81A 2OU6A 3HLZA 5A6AA 1ORJA 3DI5A 1LI5A 3NYJA 5DS6A 4MTOA 2ICWG 3I5QA 1E84A 3MYIA 1M2VB 4KNWA 1D1AA 4IGGA 2WZFA 2LCHA 4NTFA 1OXKA 3ZQYA 3VRCA 2A0BA 3RVZA 5L0HA 1I5NA 4O6NA 3B0UX 4XQ1A 3Q7LA 2GDCA 2HKVA 1BDJB 1OCCC 1HE9A 2AU5A 2CDQA 2XRHA 3ATPA 4XPXA 3UNGC 4CS8C 2HUJA 3TULA 3POVA 3SNHA 5B3IA 4PFOA 2KK1A 2L6HA 2Y69C 2H8AA 3O55A 1WN0A 1A7VA 2DI3A 1OKKA 2VCCA 3S27A 2KJGA 4HFFB 5BQGA 4DRHB 1M56C 3ZWIA 2IYLD 4BG0A 5DLJA 5EK0A 1M2OA 4I44A 5COMA 4YT8A 5KYUA 1Q0KA 1Q0FA 2Q7RA 5T3WA 4AL1A 1YLMA 4PJLA 3IHUA 4Z9IA 4LDQA 3O39A 3UGOA 3SP1A 4L6RA 2EINC 5EGYA 4CJOA 1ZW2A 3EHNA 4JW1A 3SXMA 1FR0A 1PD1A 1QQ3A 4BJ5A 4YT2A 2CW0F 2I8BA 3SXYA 3ZTMA 3UMHA 5KYUB 2IXNA 3KL4A 2R7UA 4G7OF 4GYTA 1AEPA 1LIHA 2L7AA 4JC7A 4MS2A 3ZVRA 5L0CA 3SXZA 3QVZA 5B1AC 4O6MA 5F28E 3T4RA 1UFBA 2TMVP 1HY5A 2J9BA 1OCOC 2YVKA 3ZQVA 2IXMA 2YL0A 3FAPB 3ZC4A 2KQ9A 2OQMA 2GA0A 5COGA 3WAQA 2DGJA 4GQHA 1CPQA 2A1DD 2R7TA 4AE4A 3FOOA 3AGUA 1V74B 3DD7A 2VCAA 3UGPA 3S29A 1FMWA 1EQ1A 2NPUA 1NU9C 3TOMA 3GM2A 3TK0A 3F47A 1QZXA 4E7SA 1XZQA 1JMWA 1RXQA 3G50A 1J8YF 1O5HA 1OCRC 3KYJA 3GM1A 3H2VA 1JOGA 4K1OA 4MW8A 1A0BA 3FOPA 3IQTA 2I15A 4QI0A 3EH1A 3GORA 4OIPF 2R7VA 1VYIA 1B68A 1OQCA 3MBGA 4G7ZF
chains in the Genus database with same CATH topology
2GAQA 2RSEB 5GPGB 2NPUA 3FAPB 2FAPB 4DRIB 4FAPB 1FAPB 4DRHB 1AUEA 1NSGB 4DRJB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GAQ A;  2RSE B;  5GPG B;  2NPU A;  3FAP B;  2FAP B;  4DRI B;  4FAP B;  1FAP B;  4DRH B;  1AUE A;  1NSG B;  4DRJ B; 
#chains in the Genus database with same CATH topology
 5L0D A;  3C18 A;  3IQ6 A;  3J06 A;  2KGO A;  3U5S A;  4NC3 A;  2WZL A;  4CIP A;  2MYS A;  2YHS A;  3I4U A;  3E70 C;  3ABL C;  4XEF A;  1MMG A;  1Y4C A;  4N06 A;  2HMZ A;  5JP7 A;  2CNW D;  1SZI A;  2ZPA A;  1LI7 A;  3C62 A;  2J0W A;  3GEE A;  4X0R A;  2Y3D A;  3N24 A;  2X0C A;  1GGQ A;  2YL3 A;  1G4U S;  1Z6A A;  4IAR A;  4BJ5 C;  2J9W A;  3JSE O;  3LS1 A;  3WG7 C;  1Z5Z A;  3V7O A;  1Q0G A;  1YYJ A;  2OEX A;  1CGN A;  1HMO A;  1TFK B;  3EG9 A;  2OEV A;  3HNI A;  3K7D A;  2LD6 A;  3EGD A;  3CEX A;  1RJ9 B;  4YK5 A;  3TJ5 A;  1M6T A;  4U5B E;  1TR2 A;  4LAC B;  4MTF A;  3I5P A;  4JJF A;  4ZLD A;  3K33 A;  2R25 A;  1KU2 A;  4CBE A;  4JTA B;  1NSG B;  1RKC A;  4BEM J;  2KC3 A;  3JTL O;  3EGX A;  4JCH A;  4IWB A;  2XLM A;  2R7O A;  1NBB A;  4Z9J A;  2B0H A;  1EA8 A;  1JR8 A;  3HKK A;  5K0I A;  5KYX A;  1TWH A;  1C03 A;  3EG9 B;  4FES A;  3US6 A;  1D0Y A;  2YZS A;  4U9E A;  3JCU Q;  3KPH A;  4Q5S F;  1HW1 A;  2OG2 A;  2EPK X;  3DM5 A;  3NKE A;  2P1A A;  3C8Z A;  3GM3 A;  2QUP A;  1CPR A;  3JSZ A;  1VYK A;  2KNH A;  2W9Y A;  4W8K A;  3EGX B;  3S9O A;  2ZXW C;  4C7O B;  3K1H A;  1EI7 A;  1IZM A;  2L6G A;  3RYL A;  4E7Z A;  5KYX B;  3ASN C;  4B6I A;  3B9Q A;  4YJW A;  1U89 A;  5EHH A;  4PAC A;  2R7R A;  4MND A;  3HTK C;  3EPV A;  4YWQ A;  3IPM O;  1WAS A;  3LUT B;  4YT4 A;  2HZ8 A;  5BQI A;  3RF3 A;  3ZDL A;  1OW7 A;  1ZHZ A;  2HSQ A;  4G78 A;  4JJG A;  3T9O A;  4EUK B;  3S0X A;  2XXA A;  3TJ6 A;  3U3F A;  1ORY A;  2R9R B;  2AWC A;  4YL0 A;  1ORS C;  5CI9 A;  2YKZ A;  2J9U A;  4MTG A;  3ZIB A;  4AE4 B;  1QPU A;  5E3C A;  3R2P A;  4H4K C;  3RVY A;  2P7V A;  2P6V A;  4JEA A;  2HJ3 A;  2W45 A;  3HNL A;  1ZYR F;  2Q9C A;  2Y3H A;  2YRF A;  2ETS A;  3NYM A;  3SYN A;  1ZVZ A;  4H54 A;  3AGT A;  4O7G A;  4F4B A;  1MMD A;  2XXA B;  5GPG B;  1APC A;  1U0B B;  3B0P A;  4G0H A;  5CI8 A;  4K7B A;  1KNY A;  1RKE A;  3JYY A;  2WVN A;  3VF0 A;  4PJJ A;  1MMA A;  1VOM A;  2G3K A;  1YDI A;  2MHR A;  3K1I A;  1T5O A;  4EBB A;  1XZP A;  1LPE A;  3DKA A;  3HNJ A;  1VLT A;  3E9V A;  4HE8 D;  4JRZ A;  4K0D A;  3W8I A;  3W8H A;  3ASO C;  1Z7Q c;  2Y3G A;  3U2L A;  4CJG A;  1UG7 A;  4CIH A;  5JVE A;  4WGZ A;  5D92 A;  4Q4Z F;  1RKE B;  3GOD A;  4U5G A;  2XM4 A;  1K05 A;  3N2Z B;  2HMQ A;  3AG2 C;  2R05 A;  1YZA A;  2PFD A;  5IY5 C;  5DS5 A;  2XS8 A;  4BEJ A;  1N1C A;  5A6B A;  2P0N A;  4JTC B;  4IRU A;  4MVU A;  1AVO B;  1Q0D A;  2XLO A;  3JRM O;  4XPY A;  3SXK A;  2HV7 A;  2J9V A;  4EWC A;  3EHM A;  1JAF A;  1CGM E;  1GQA A;  1LE2 A;  1VLS A;  3FVY A;  4U5D E;  2H7B A;  2Q00 A;  1ZHW A;  2F22 A;  1TQG A;  4DOZ A;  2EPL X;  2EPN A;  2CYD A;  3NRH A;  2A6E F;  2PF4 E;  3LLI A;  1K40 A;  4R32 A;  2EIL C;  2J46 A;  3M1C B;  4DXW A;  3FAJ A;  2PX0 A;  2YEV A;  3BEH A;  1Z3I X;  1OXB A;  3LJB A;  4JIO A;  3B0V C;  3IEE A;  3VYW A;  4PFP A;  1HE1 A;  5F5F A;  1FAP B;  1D0Z A;  3AG1 C;  2LSE A;  4D4N A;  4U5E E;  2CGE A;  3W2V A;  1R4T A;  2LFD A;  3GAN A;  2NSF A;  2PX3 A;  1PD0 A;  2H7O A;  1ZZP A;  4CSA A;  3W4Y A;  1TWG A;  3FDQ A;  1VK5 A;  5JSL A;  1OCZ C;  3MYF A;  3Q7G A;  4O79 A;  3NG1 A;  3OA1 A;  1VMA A;  3K1I C;  3OEO A;  3L8J A;  4U5H A;  4A2N B;  1E83 A;  4RDA A;  3CQZ A;  3ZSU A;  5CIV A;  4HEA J;  2VAS A;  3W2W A;  5DQZ A;  1NZE A;  5JRA A;  5L3Q A;  3NMJ A;  1FFT C;  4RBN A;  1LVK A;  1LS4 A;  2BC5 A;  3OWT A;  4DRI B;  4E0H A;  4A4A A;  1HW2 A;  3K66 A;  2PP4 A;  2WZG A;  1H9T A;  2A0U A;  2J7P D;  1U6H A;  2UUI A;  3AJM A;  1G4W R;  2NG1 A;  1YA9 A;  3MLG A;  2DYS C;  4BPM A;  3M4C A;  3TD7 A;  3H65 A;  1C17 M;  3U9J A;  5A6J A;  1RJ9 A;  3CSK A;  1Z23 A;  4MVO A;  1E85 A;  4BJT A;  4ULW A;  4MVZ A;  4DBR A;  3LLK A;  2E87 A;  4JE9 A;  2C03 A;  3LEV A;  2Q3T A;  1WAT A;  1IW7 F;  3O10 A;  1T9K A;  3DMD A;  3PCV A;  2V3C C;  4CDA A;  1LE4 A;  2HV6 A;  2YLI A;  1S7Z A;  1ST6 A;  2FFH A;  4ZLC A;  3ABK C;  3FHD A;  3PMR A;  1TFO B;  4JTD B;  5FZT A;  3RQG A;  2QY9 A;  4JCZ A;  1R5I D;  1FNT c;  1TWA A;  2XM0 A;  1BZ4 A;  4JZA A;  5D91 A;  5KYY B;  3U2M A;  4M63 A;  2M64 A;  2C04 A;  2DYR C;  4U5C E;  1T6Q A;  2BE5 F;  2UUH A;  1D0X A;  1ZHY A;  2ZXR A;  1NFN A;  3Q6M A;  2GWW A;  1BR4 A;  3QZC A;  4ONS A;  4CSA C;  4C7O A;  5KYW A;  1LKX A;  1Q0M A;  1OR2 A;  1OR3 A;  2YWA A;  4ULV A;  4WGY A;  1T6U A;  3PDM P;  4I1O B;  3EFO A;  4XLP F;  3NMI A;  4MVQ A;  5BUO A;  2D4U A;  1FMV A;  1G8X A;  1L3P A;  3QMK A;  1WWP A;  1VB5 A;  4HFK B;  4J32 B;  3DJU B;  4J30 B;  4PJM A;  4XTK A;  3RIP A;  5BQH A;  2HJM A;  3ITF A;  3MX3 A;  4C3E A;  4EHP A;  4JKV A;  2J7P A;  4Q7C A;  4Z9H A;  3AOU A;  3QW0 A;  5DVW A;  5KYW B;  4EBK A;  1ZU4 A;  2QLA A;  1LS1 A;  4DBQ A;  2AP3 A;  4OIO F;  3PHF 2;  3RH3 A;  3EFO B;  1W2W A;  2FAP B;  4D4X A;  2KYH A;  3NMK A;  4XEV A;  1HMD A;  2CNW A;  3N0T A;  3AQB A;  3ZTZ A;  2OOC A;  2LFF A;  3IQC A;  4P6I C;  3U8P A;  2HS5 A;  3V5Y A;  1WGW A;  4IAQ A;  2PNO A;  5JT4 A;  1YYX A;  2G3V A;  3QTH A;  4KBL A;  1VTM P;  3GWN A;  4CDY A;  2NSG A;  1NG1 A;  1WOL A;  3LNM B;  5L3V A;  1F1M A;  3V5Z A;  1H6G A;  1SMY F;  2D5R B;  2LQG A;  2ZXO A;  4I1M A;  1FFH A;  2J0X A;  1YAU O;  2L9J A;  3GEH A;  4YL3 A;  3UR3 C;  1OKK D;  3UMI A;  3T6G B;  1CGO A;  3A11 A;  2RSE B;  3HJC A;  4P9T A;  4PK4 A;  1WTY A;  2VCB A;  3X2Q C;  4EBJ A;  2R7W A;  5KYY A;  2ASR A;  3T6B A;  1LM3 B;  5COF A;  4NTB A;  2CCY A;  4NY3 A;  2VC9 A;  4XEK A;  3DJN B;  4AX2 A;  3IQ5 A;  4NTA A;  5HV9 A;  3DE8 A;  3O6X A;  3U0C A;  2LIG A;  5JLI A;  1V54 C;  2YL7 A;  3DAF A;  1YJG A;  4DRJ B;  1YZC A;  2XS1 A;  5L0J A;  5T3T A;  2XLH A;  4ANJ A;  1T6I A;  2YLD A;  1O3U A;  3R7C A;  4C3D A;  2Q9A A;  2XLV A;  1QLE C;  4U5F E;  2B0J A;  4WAB A;  3TOL A;  5F5H A;  4OIN F;  3VM6 A;  4GEH A;  4DVZ A;  3NKD A;  1MND A;  1SYQ A;  1XWJ A;  3DAG A;  2BL2 A;  3WHN A;  4P9F A;  2X51 A;  3DWW A;  3DXJ F;  1NFO A;  3A9C A;  5A69 A;  5HSW A;  1O87 A;  3EZI A;  3HNK A;  3EJN A;  4CS9 A;  5AC5 A;  3TQO A;  4MVS A;  1TKN A;  4U9D A;  4ER9 A;  3JT1 A;  3DE9 A;  3AG4 C;  1NU7 D;  3U8V A;  4CDV A;  3B71 A;  1D1B A;  4O6Y A;  5KYN A;  4EIY A;  4N4W A;  3L1M A;  1H9G A;  1PV3 A;  3QW1 A;  4UDV A;  4MQ9 F;  4XWJ A;  4N6C A;  1Y6D A;  1YVI A;  4FWV A;  1A7D A;  4JEB A;  4KNV A;  1DOW A;  4KC9 A;  3EH2 A;  3DM9 B;  2Q4F A;  5AGF A;  2PBE A;  4C3B A;  4N6H A;  3DZA A;  3SZR A;  1V55 C;  2LK4 A;  2R03 A;  2XSE A;  2NUT A;  4MVM A;  5L0I A;  2OJQ A;  2OKU A;  2AWY A;  4OIR F;  3LS0 A;  3RKO F;  3ZG1 A;  2XL8 A;  3L34 A;  2V26 A;  4EKW A;  2JD3 A;  2LP4 A;  2WVQ A;  3SEO A;  3JYH A;  1GS9 A;  3C8G D;  1QVX A;  5B1B C;  2R7S A;  2ZD9 A;  4YN0 B;  4YL1 A;  3LES A;  2YLG A;  4LDR A;  3V5X A;  3M4B A;  4YT5 A;  2NUT B;  4BJ6 A;  1RMV A;  3FMS A;  3NDB B;  1SR2 A;  2IOQ A;  3K6B A;  1QSP A;  2Q9B A;  2VB6 A;  5T1D B;  1MQV A;  1S05 A;  2DB4 A;  2OCC C;  3JZ0 A;  2QTV A;  2XL4 A;  2WL8 A;  2XLD A;  1M57 C;  2R02 A;  4RD9 A;  5JS5 A;  5L0G A;  3CAX A;  3M79 A;  3RQE A;  4CS9 C;  2VH3 A;  2XLE A;  2NUP A;  2RD9 A;  3QVY A;  3G4X A;  4JUR I;  1DOV A;  4NQF A;  3S90 A;  1YAR O;  3T6J A;  256B A;  2OJE D;  1G5Z A;  2WB7 A;  3ABM C;  1ZW3 A;  1T01 A;  4I3M A;  4J7T A;  5A6K A;  2A6H F;  4FAP B;  1MNE A;  1ZHT A;  3KYI A;  4DJ9 A;  3GEI A;  3FXH A;  4E17 A;  2QE9 A;  5E2Q A;  2H7V C;  3AG3 C;  1ZHX A;  4DVY P;  2QNL A;  2NUP B;  2Y3B A;  3WOD F;  1JPN A;  3MFN A;  2R7Q A;  2YQY A;  1A7E A;  2HFI A;  2A69 F;  4OD5 A;  4QDL A;  5B3S C;  1EKY A;  3B29 A;  1BBH A;  2YL1 A;  1YA7 O;  3NYL A;  5E3A A;  4FX5 A;  3C8G A;  3LEO A;  4LLC A;  3KMI A;  2KW3 C;  2WVO A;  4IB4 A;  4CS7 A;  3L0I A;  2XLW A;  4XLN F;  4IJJ A;  4AL0 A;  1C02 A;  4AK9 A;  1SF8 A;  4OD4 A;  4BJ1 A;  2Z15 A;  3JRT A;  3UMK A;  2R7X A;  4J7Y A;  3LAY A;  4JVS A;  1K04 A;  2GAQ A;  3LNR A;  1JRA A;  4BJ6 C;  5E33 A;  1OW8 A;  2IM8 A;  3C8G B;  2EPM X;  3L8I A;  3AQC A;  3RFY A;  1MMN A;  3H2U A;  5DQT A;  3C63 A;  3U9M A;  5JUA A;  3C7J A;  5TJ5 E;  1JPJ A;  4MW3 A;  4NCQ A;  3M15 A;  2L6F A;  2W4M A;  3Q6N A;  1PCX A;  4IAO A;  1RCP A;  3U3B A;  1E86 A;  2MWQ A;  2FGY A;  3EQL F;  1QKR A;  1ZU5 A;  2O9X A;  4G7H F;  4CS8 A;  3EGD B;  2M4E A;  4LER A;  2KSF A;  2EIK C;  1BR1 A;  4WJ0 A;  1TWC A;  1A41 A;  5AC4 A;  1OW6 A;  1E2X A;  4KI2 A;  2W4B A;  4OIQ F;  1BR2 A;  2Y39 A;  3BRJ A;  4PJN A;  3RW0 A;  1Z63 A;  4W8P A;  3S84 A;  4E18 A;  2EIJ C;  2J45 A;  1J8M F;  1D1C A;  1KTM A;  3EZH A;  4PR9 A;  2P61 A;  4MVR A;  5FCL A;  3GWL A;  4QI2 A;  3F46 A;  1L7C A;  2JX0 A;  2GFH A;  4LLE A;  4LDK A;  2XL6 A;  2JPU A;  5A6B D;  2IBF A;  4XPW A;  3ECS A;  1FTS A;  2G62 A;  1I4Z A;  3KKB A;  2J8W A;  2IXP A;  1M2V A;  3S28 A;  5L0F A;  2EIM C;  2A68 F;  1NLX A;  2HSB A;  2ZXP A;  2IXO A;  3CZ6 A;  5DS4 A;  1V4A A;  1I4Y A;  3KH2 A;  1H7I A;  3RQF A;  2EPO A;  2AVK A;  1AUE A;  3G4Z A;  1GM5 A;  4E0I A;  4CX9 A;  3X1O A;  3VAY A;  2L81 A;  2OU6 A;  3HLZ A;  5A6A A;  1ORJ A;  3DI5 A;  1LI5 A;  3NYJ A;  5DS6 A;  4MTO A;  2ICW G;  3I5Q A;  1E84 A;  3MYI A;  1M2V B;  4KNW A;  1D1A A;  4IGG A;  2WZF A;  2LCH A;  4NTF A;  1OXK A;  3ZQY A;  3VRC A;  2A0B A;  3RVZ A;  5L0H A;  1I5N A;  4O6N A;  3B0U X;  4XQ1 A;  3Q7L A;  2GDC A;  2HKV A;  1BDJ B;  1OCC C;  1HE9 A;  2AU5 A;  2CDQ A;  2XRH A;  3ATP A;  4XPX A;  3UNG C;  4CS8 C;  2HUJ A;  3TUL A;  3POV A;  3SNH A;  5B3I A;  4PFO A;  2KK1 A;  2L6H A;  2Y69 C;  2H8A A;  3O55 A;  1WN0 A;  1A7V A;  2DI3 A;  1OKK A;  2VCC A;  3S27 A;  2KJG A;  4HFF B;  5BQG A;  4DRH B;  1M56 C;  3ZWI A;  2IYL D;  4BG0 A;  5DLJ A;  5EK0 A;  1M2O A;  4I44 A;  5COM A;  4YT8 A;  5KYU A;  1Q0K A;  1Q0F A;  2Q7R A;  5T3W A;  4AL1 A;  1YLM A;  4PJL A;  3IHU A;  4Z9I A;  4LDQ A;  3O39 A;  3UGO A;  3SP1 A;  4L6R A;  2EIN C;  5EGY A;  4CJO A;  1ZW2 A;  3EHN A;  4JW1 A;  3SXM A;  1FR0 A;  1PD1 A;  1QQ3 A;  4BJ5 A;  4YT2 A;  2CW0 F;  2I8B A;  3SXY A;  3ZTM A;  3UMH A;  5KYU B;  2IXN A;  3KL4 A;  2R7U A;  4G7O F;  4GYT A;  1AEP A;  1LIH A;  2L7A A;  4JC7 A;  4MS2 A;  3ZVR A;  5L0C A;  3SXZ A;  3QVZ A;  5B1A C;  4O6M A;  5F28 E;  3T4R A;  1UFB A;  2TMV P;  1HY5 A;  2J9B A;  1OCO C;  2YVK A;  3ZQV A;  2IXM A;  2YL0 A;  3FAP B;  3ZC4 A;  2KQ9 A;  2OQM A;  2GA0 A;  5COG A;  3WAQ A;  2DGJ A;  4GQH A;  1CPQ A;  2A1D D;  2R7T A;  4AE4 A;  3FOO A;  3AGU A;  1V74 B;  3DD7 A;  2VCA A;  3UGP A;  3S29 A;  1FMW A;  1EQ1 A;  2NPU A;  1NU9 C;  3TOM A;  3GM2 A;  3TK0 A;  3F47 A;  1QZX A;  4E7S A;  1XZQ A;  1JMW A;  1RXQ A;  3G50 A;  1J8Y F;  1O5H A;  1OCR C;  3KYJ A;  3GM1 A;  3H2V A;  1JOG A;  4K1O A;  4MW8 A;  1A0B A;  3FOP A;  3IQT A;  2I15 A;  4QI0 A;  3EH1 A;  3GOR A;  4OIP F;  2R7V A;  1VYI A;  1B68 A;  1OQC A;  3MBG A;  4G7Z F; 
#chains in the Genus database with same CATH homology
 2GAQ A;  2RSE B;  5GPG B;  2NPU A;  3FAP B;  2FAP B;  4DRI B;  4FAP B;  1FAP B;  4DRH B;  1AUE A;  1NSG B;  4DRJ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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