4DRJB

O-crystal structure of the ppiase domain of fkbp52, rapamycin and the frb fragment of mtor
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
96
structure length
96
Chain Sequence
MDPEFMEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Peptidyl-prolyl cis-trans isomerase FKBP4
publication title Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Isomerase/transferase
total genus 40
structure length 96
sequence length 96
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2012-02-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.150 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) FKBP12-rapamycin binding domain 4drjB00
4DRJB 1NSGB 2GAQA 3FAPB 1AUEA 4DRHB 5GPGB 4DRIB 1FAPB 2RSEB 2NPUA 2FAPB 4FAPB
chains in the Genus database with same CATH superfamily
2R7VA 1KTMA 4E7ZA 3S9OA 3JRMO 3PHF2 5L0IA 2HMZA 2W45A 3DM9B 4I1OB 2Q00A 1KNYA 1GGQA 1RKEB 2WVQA 1WATA 2W9YA 3IQTA 3JRTA 1QPUA 4EHPA 3PMRA 2PX3A 3LNMB 4IB4A 3R2PA 1MNEA 4JTAB 1D0XA 4LLCA 2R7RA 1TWCA 4X0RA 3RFYA 1T01A 3NYLA 2W4MA 1KU2A 2KK1A 4K1OA 3GANA 2YLIA 3K6BA 3AG1C 1L7CA 1Q0FA 2DGJA 2ZXPA 2XL4A 3DJNB 1S05A 2XXAB 4BEMJ 2EIJC 2WVNA 4MVQA 1RKCA 4E17A 3RKOF 2PFDA 3NDBB 2KYHA 2H7VC 2L7AA 2VASA 4C7OA 5A6BD 2ZXWC 3LLKA 3EQLF 1OR3A 2Z15A 2V3CC 4W8KA 1NZEA 3SXMA 4YL3A 2XL6A 1VTMP 3KPHA 3CAXA 3QTHA 2IXOA 3HKKA 2NUPA 4DOZA 3CSKA 2DYRC 4OIRF 3CQZA 3IQ5A 5DS5A 3IEEA 3NRHA 4PK4A 2EPMX 2EPKX 3MLGA 5JS5A 2G3VA 2P61A 4JJGA 4DRIB 3EFOA 1OCZC 1YA7O 2AWCA 2OG2A 3DZAA 3EG9A 1DOVA 2L6FA 1LI5A 1Y6DA 4XQ1A 2P6VA 3ECSA 4O6NA 1BR1A 5FCLA 2ASRA 2A1DD 4IGGA 4J32B 4ONSA 3G4ZA 3U9MA 4K7BA 1RCPA 3RF3A 4DBQA 5L0DA 3AQCA 3A11A 3TOLA 4BPMA 4N6HA 1T6UA 1BBHA 2PP4A 4JIOA 5HV9A 1RJ9B 2VH3A 4J7TA 1NU9C 2AWYA 5JSLA 1YA9A 4E7SA 2XLHA 1TKNA 2IXMA 2LP4A 1AVOB 4KI2A 2GA0A 3LEOA 4ZLCA 4M63A 2FGYA 2KQ9A 2YL3A 3Q7GA 3SYNA 4DXWA 4ANJA 3HLZA 2I8BA 3EH2A 4MQ9F 5EK0A 2M4EA 4PJMA 4U5HA 5COFA 5T3WA 2OKUA 3KYIA 4A2NB 4GEHA 2OQMA 3GEHA 3EJNA 1PCXA 2EILC 1LVKA 4GQHA 3JZ0A 1ZW3A 3GM2A 3VYWA 2OEXA 3U2LA 3PDMP 1A7EA 3K1IC 2EIKC 3GODA 2QUPA 5JP7A 3SXKA 3L0IA 4F4BA 2GWWA 4I1MA 3L34A 4MVUA 3W8HA 4BJ5C 4D4NA 1J8YF 2J0WA 4BJ1A 3QZCA 3ASNC 4EBBA 1GQAA 4CS8A 3F46A 4XEVA 4CDAA 4LACB 2A69F 4YK5A 4O7GA 1WWPA 2HSQA 4WABA 4XEKA 4XEFA 1LIHA 3O10A 4JVSA 1ZVZA 5GPGB 5L0JA 1FNTc 3Q6NA 4G7OF 1V4AA 2LSEA 1V55C 2HV6A 4CS9C 4E0IA 2L6HA 2YQYA 3NMKA 3RVYA 3U3FA 5JRAA 4XLNF 1QSPA 3S29A 2CNWA 1YVIA 5A6AA 2B0HA 3G4XA 4LDRA 4ULVA 1LPEA 3HNJA 5BQHA 3ZTMA 1ZHYA 4BG0A 1A41A 2NUTB 1NG1A 4P6IC 2Q9CA 1T5OA 3C7JA 4RD9A 1FMWA 4U5CE 5KYWB 4YT2A 1Z63A 1T9KA 4N06A 5DS4A 4YWQA 4YJWA 1OCOC 1H7IA 2EPOA 4XLPF 2Y3HA 3K33A 3MX3A 4IAQA 5BUOA 3RQEA 1YARO 4WGZA 4QI2A 1NFNA 3NG1A 5HSWA 2I15A 1HY5A 3EGXA 2G3KA 3M15A 2HUJA 2A6HF 4JE9A 3H2UA 2J9WA 2YVKA 3GEEA 3LEVA 2W4BA 3DE9A 2XSEA 4BJ6A 4DVYP 2OOCA 4EUKB 2XL8A 2IYLD 1YZCA 1JOGA 3OWTA 1IW7F 4U5FE 5A6BA 4C3BA 1D1CA 2DYSC 4JZAA 3T6BA 1A7VA 1LE4A 3EHMA 3CEXA 3CZ6A 1PV3A 1Y4CA 3WG7C 1HE1A 1RKEA 2LFFA 3W2WA 3DWWA 1D1AA 1HMOA 2LK4A 4O79A 4WJ0A 2XRHA 4GYTA 2KJGA 3E9VA 3ZVRA 1Z23A 2D4UA 2Y69C 2CYDA 1MMDA 3QW0A 4PJNA 2CDQA 4CJOA 4CBEA 1XZQA 4PJJA 1AUEA 2AU5A 3DM5A 1EI7A 4EKWA 5BQIA 1UFBA 4JCHA 1XZPA 4W8PA 2R7QA 4G7ZF 2Q4FA 3SXZA 2LQGA 1SR2A 2DI3A 3QVYA 3C18A 1VLTA 3QMKA 4JW1A 4N6CA 4EBKA 4FAPB 4O6YA 5E33A 4NTFA 1U0BB 1W2WA 3GWLA 4AE4B 2J8WA 2AVKA 1ZYRF 2H7BA 3BEHA 1WN0A 1VK5A 2HJMA 3FOOA 3IQ6A 4XPYA 5K0IA 2AP3A 1LE2A 3S90A 1I4YA 1Z6AA 3C8GB 3UR3C 1VLSA 1XWJA 5AC4A 3GM1A 4E18A 1BZ4A 1FMVA 1U89A 3LJBA 2NG1A 4PR9A 3NMIA 3KKBA 3TULA 1Q0GA 4MTGA 3UGOA 1K40A 3B71A 2OU6A 3U5SA 4JKVA 2XLOA 3ZQVA 1HW1A 1CPRA 4JEBA 3L8JA 2VC9A 1SYQA 4PJLA 1M6TA 1RXQA 3H2VA 3FDQA 2LCHA 3MBGA 4NQFA 3KMIA 5L0CA 1OKKA 3N24A 2HSBA 4CIHA 5F5FA 1MNDA 2HS5A 2EPLX 5KYUA 2IM8A 4RDAA 1JR8A 2NSGA 2NSFA 3AG4C 3HTKC 3ZC4A 4OIPF 1FR0A 3U9JA 1RJ9A 1E86A 2E87A 2YL7A 1HW2A 5B3IA 2YWAA 3LS0A 1B68A 3FOPA 5KYYB 1J8MF 2LFDA 4H4KC 1NBBA 2GFHA 2H7OA 3AQBA 3T4RA 1OCRC 2YRFA 1I5NA 1MMAA 3OEOA 4JEAA 3A9CA 2XLDA 2V26A 3KYJA 4EWCA 2R7SA 3POVA 4CS7A 3TJ5A 4HFFB 4DVZA 3C8ZA 1E84A 2WB7A 5EHHA 3S0XA 1SZIA 2R7UA 1ZW2A 3EGDB 4LDQA 2HJ3A 3BRJA 1O3UA 3U2MA 3F47A 3NKDA 1MQVA 3DI5A 3UMIA 3L1MA 1WASA 2WZGA 1T6QA 3Q7LA 3T9OA 2KSFA 2VCAA 2DB4A 2YL0A 1OKKD 1ZU5A 3DD7A 4UDVA 4I3MA 5E2QA 2OJQA 3S28A 3I5QA 1HMDA 1APCA 3ITFA 1E83A 1DOWA 3U8PA 1FFTC 4DRHB 5CI8A 1N1CA 5B1AC 1FAPB 4WGYA 4EIYA 4HEAJ 4OIOF 1O87A 1TWHA 4U5BE 1QKRA 2XS1A 2WZFA 3RQFA 1Z7Qc 3UNGC 4IWBA 3SZRA 1M2VA 2C04A 2C03A 3LLIA 4CJGA 3LNRA 1F1MA 4IARA 3V5XA 2ICWG 1WTYA 1VB5A 1TWGA 2Y39A 2Q3TA 5B3SC 2OCCC 5EGYA 3H65A 1TWAA 4CDVA 2L81A 1K05A 1RMVA 2PF4E 1VMAA 3EPVA 4J7YA 1E85A 2HV7A 2A68F 1JAFA 2XM4A 2QE9A 3UMHA 4XPWA 4YT8A 1IZMA 3ZDLA 4N4WA 3ZWIA 5AC5A 5KYWA 1LS4A 4MVOA 4PFOA 1QZXA 1M57C 2YZSA 4MTFA 1K04A 3MYFA 3VAYA 3J06A 4MW3A 3JYYA 3TJ6A 4MNDA 1I4ZA 5T1DB 4CX9A 1BR4A 4KNWA 2L9JA 1ORJA 3JT1A 3WODF 1CGOA 2Q9AA 3JTLO 3GWNA 4K0DA 4G78A 2UUIA 2P7VA 2P1AA 4G0HA 1M2OA 2YHSA 3FAPB 3G50A 2HKVA 3WAQA 3LAYA 4MVZA 1C03A 4Q5SF 1ORYA 2R03A 2JD3A 3I4UA 3T6GB 3O39A 2YLGA 4IJJA 4C3DA 4Q4ZF 3ATPA 4JJFA 5TJ5E 1OXBA 2VB6A 1S7ZA 2R9RB 4U5DE 1Z3IX 1H6GA 2Q7RA 1JPJA 1TR2A 2NPUA 2VCCA 4KBLA 5COGA 1CGME 3DKAA 2GAQA 1TFKB 3W8IA 1ZHTA 3JYHA 3S27A 3AJMA 1FFHA 3SXYA 3ASOC 1OW6A 2B0JA 2XM0A 2J9VA 3DE8A 1VYKA 3K1HA 3LESA 3EH1A 4U5EE 1YYJA 3HJCA 1CPQA 4Z9IA 1EQ1A 3VM6A 2KGOA 2H8AA 4MVMA 4P9FA 1G5ZA 2X0CA 4AX2A 4EBJA 2OEVA 1Q0DA 3W2VA 1A0BA 2D5RB 4BJ6C 1A7DA 1ZU4A 2LD6A 5KYXB 3B0UX 5L0GA 1NU7D 1UG7A 2YEVA 2XXAA 2F22A 5DS6A 3ZSUA 3EGXB 3WHNA 4NC3A 4AE4A 3LS1A 5L0FA 1R4TA 5DQZA 1WOLA 2JPUA 2YKZA 3HNKA 1Q0MA 4MW8A 1JMWA 2M64A 2ZXRA 3C8GA 1MMGA 1EA8A 3RW0A 3VF0A 2PX0A 2XLEA 3ABMC 3X2QC 2CCYA 3FMSA 5F28E 4G7HF 5FZTA 3E70C 2PNOA 3DAGA 5CI9A 2ETSA 3I5PA 2R7OA 4OD4A 5D92A 4B6IA 5T3TA 4CSAC 1FTSA 3MFNA 4IAOA 4D4XA 3ZQYA 2P0NA 5A6KA 5F5HA 3DXJF 5COMA 3DMDA 1ZHXA 3Q6MA 2WVOA 2BC5A 2WZLA 1V74B 4YT5A 2EIMC 2QY9A 2TMVP 2BL2A 4JURI 3QW1A 2IXNA 3FAJA 2MHRA 3IPMO 2VCBA 1LS1A 2MWQA 4PFPA 3C62A 2PBEA 2CGEA 3O55A 3TK0A 1ZZPA 2FAPB 1H9GA 4C7OB 4CSAA 1NSGB 5KYYA 2IOQA 3C8GD 3IQCA 3K66A 1ZHWA 2XS8A 3OA1A 4P9TA 3X1OA 4OIQF 3SEOA 3IHUA 5E3AA 4RBNA 4Q7CA 3AG3C 1R5ID 2Q9BA 3JSEO 3TD7A 3U0CA 2NUPB 3W4YA 4OD5A 2Y3DA 2KW3C 4CIPA 1OW8A 3EGDA 3SP1A 1D1BA 3RIPA 4NCQA 3M79A 3N0TA 2CW0F 4MS2A 3EFOB 4MVSA 1AEPA 3JCUQ 1QQ3A 4FESA 3EG9B 4YL1A 4Z9HA 4FX5A 1VOMA 4J30B 3GEIA 4LERA 1T6IA 1YLMA 3U8VA 3NKEA 4JTCB 5L3VA 1EKYA 4MTOA 5DQTA 2LIGA 5KYUB 1V54C 2J9UA 5KYNA 2IXPA 4XPXA 2GDCA 3LUTB 1YYXA 3GM3A 4YN0B 2XLVA 4KC9A 4XWJA 3K1IA 2R7TA 3M1CB 2X51A 1O5HA 1GS9A 2L6GA 3FXHA 3RVZA 3KL4A 4BJ5A 4U9EA 2R7XA 1PD0A 3AGUA 2HZ8A 3NYJA 1SF8A 4ER9A 4U9DA 4R32A 1JPNA 3M4BA 1LI7A 3JSZA 3L8IA 3PCVA 2HFIA 1MMNA 1D0YA 1QLEC 3K7DA 2YL1A 2G62A 3DJUB 1TQGA 5E3CA 1ZHZA 2A0UA 2QNLA 2EINC 5B1BC 2EPNA 3B9QA 4JC7A 2IBFA 4O6MA 4ULWA 1SMYF 2ZD9A 1L3PA 3RQGA 3ZIBA 1H9TA 3NMJA 3B29A 4YL0A 3T6JA 1WGWA 2QLAA 4CS8C 1OR2A 3EZHA 2Y3BA 2FFHA 2ZPAA 4DBRA 2QTVA 3U3BA 1YDIA 4CS9A 5JLIA 5DVWA 3AGTA 1HE9A 3MYIA 4U5GA 3V7OA 3ZG1A 4BEJA 2NUTA 1GM5A 2KC3A 5D91A 3RYLA 5L0HA 1NFOA 5CIVA 5BQGA 3KH2A 2J0XA 1OXKA 4NTAA 2HMQA 1G4US 1U6HA 1ORSC 2Y3GA 4DJ9A 1G4WR 3TOMA 5JUAA 4JTDB 1OCCC 1M2VB 2A6EF 2A0BA 2MYSA 1C02A 3NYMA 1BR2A 1C17M 1JRAA 4H54A 4LDKA 1NLXA 3HNLA 1M56C 3N2ZB 1PD1A 3EZIA 3R7CA 5JT4A 3C63A 3SNHA 2R02A 1D0ZA 4A4AA 4C3EA 1E2XA 2J46A 2JX0A 2R25A 2J45A 2J7PA 2WL8A 1YZAA 3S84A 2OJED 4NY3A 4YT4A 3ABLC 4NTBA 3UGPA 1TFOB 256BA 4E0HA 3FVYA 2RSEB 2ZXOA 4JRZA 1G8XA 5A6JA 4AL1A 2YLDA 4ZLDA 1CGNA 4DRJB 3HNIA 4HE8D 3V5YA 1ST6A 1YAUO 4L6RA 5AGFA 4OINF 4I44A 5A69A 4MVRA 4QI0A 2R05A 3UMKA 4IRUA 1Q0KA 4LLEA 4XTKA 4BJTA 4Z9JA 3V5ZA 4KNVA 1LKXA 3ZTZA 2J9BA 3B0PA 2BE5F 3DAFA 1QVXA 5KYXA 3ABKC 3QVZA 4AL0A 1OW7A 1VYIA 4JCZA 1YJGA 1LM3B 3AOUA 4HFKB 1Z5ZA 2O9XA 5DLJA 3FHDA 1BDJB 2XLMA 4FWVA 4CDYA 2R7WA 3B0VC 5JVEA 3GORA 3EHNA 4PACA 3O6XA 3TQOA 2XLWA 2J7PD 2UUHA 4QDLA 3M4CA 2KNHA 2CNWD 3AG2C 3RH3A 4AK9A 2RD9A 1OQCA 3US6A 3VRCA 5IY5C 5L3QA
chains in the Genus database with same CATH topology
4DRJB 1NSGB 2GAQA 3FAPB 1AUEA 4DRHB 5GPGB 4DRIB 1FAPB 2RSEB 2NPUA 2FAPB 4FAPB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DRJ B;  1NSG B;  2GAQ A;  3FAP B;  1AUE A;  4DRH B;  5GPG B;  4DRI B;  1FAP B;  2RSE B;  2NPU A;  2FAP B;  4FAP B; 
#chains in the Genus database with same CATH topology
 2R7V A;  1KTM A;  4E7Z A;  3S9O A;  3JRM O;  3PHF 2;  5L0I A;  2HMZ A;  2W45 A;  3DM9 B;  4I1O B;  2Q00 A;  1KNY A;  1GGQ A;  1RKE B;  2WVQ A;  1WAT A;  2W9Y A;  3IQT A;  3JRT A;  1QPU A;  4EHP A;  3PMR A;  2PX3 A;  3LNM B;  4IB4 A;  3R2P A;  1MNE A;  4JTA B;  1D0X A;  4LLC A;  2R7R A;  1TWC A;  4X0R A;  3RFY A;  1T01 A;  3NYL A;  2W4M A;  1KU2 A;  2KK1 A;  4K1O A;  3GAN A;  2YLI A;  3K6B A;  3AG1 C;  1L7C A;  1Q0F A;  2DGJ A;  2ZXP A;  2XL4 A;  3DJN B;  1S05 A;  2XXA B;  4BEM J;  2EIJ C;  2WVN A;  4MVQ A;  1RKC A;  4E17 A;  3RKO F;  2PFD A;  3NDB B;  2KYH A;  2H7V C;  2L7A A;  2VAS A;  4C7O A;  5A6B D;  2ZXW C;  3LLK A;  3EQL F;  1OR3 A;  2Z15 A;  2V3C C;  4W8K A;  1NZE A;  3SXM A;  4YL3 A;  2XL6 A;  1VTM P;  3KPH A;  3CAX A;  3QTH A;  2IXO A;  3HKK A;  2NUP A;  4DOZ A;  3CSK A;  2DYR C;  4OIR F;  3CQZ A;  3IQ5 A;  5DS5 A;  3IEE A;  3NRH A;  4PK4 A;  2EPM X;  2EPK X;  3MLG A;  5JS5 A;  2G3V A;  2P61 A;  4JJG A;  4DRI B;  3EFO A;  1OCZ C;  1YA7 O;  2AWC A;  2OG2 A;  3DZA A;  3EG9 A;  1DOV A;  2L6F A;  1LI5 A;  1Y6D A;  4XQ1 A;  2P6V A;  3ECS A;  4O6N A;  1BR1 A;  5FCL A;  2ASR A;  2A1D D;  4IGG A;  4J32 B;  4ONS A;  3G4Z A;  3U9M A;  4K7B A;  1RCP A;  3RF3 A;  4DBQ A;  5L0D A;  3AQC A;  3A11 A;  3TOL A;  4BPM A;  4N6H A;  1T6U A;  1BBH A;  2PP4 A;  4JIO A;  5HV9 A;  1RJ9 B;  2VH3 A;  4J7T A;  1NU9 C;  2AWY A;  5JSL A;  1YA9 A;  4E7S A;  2XLH A;  1TKN A;  2IXM A;  2LP4 A;  1AVO B;  4KI2 A;  2GA0 A;  3LEO A;  4ZLC A;  4M63 A;  2FGY A;  2KQ9 A;  2YL3 A;  3Q7G A;  3SYN A;  4DXW A;  4ANJ A;  3HLZ A;  2I8B A;  3EH2 A;  4MQ9 F;  5EK0 A;  2M4E A;  4PJM A;  4U5H A;  5COF A;  5T3W A;  2OKU A;  3KYI A;  4A2N B;  4GEH A;  2OQM A;  3GEH A;  3EJN A;  1PCX A;  2EIL C;  1LVK A;  4GQH A;  3JZ0 A;  1ZW3 A;  3GM2 A;  3VYW A;  2OEX A;  3U2L A;  3PDM P;  1A7E A;  3K1I C;  2EIK C;  3GOD A;  2QUP A;  5JP7 A;  3SXK A;  3L0I A;  4F4B A;  2GWW A;  4I1M A;  3L34 A;  4MVU A;  3W8H A;  4BJ5 C;  4D4N A;  1J8Y F;  2J0W A;  4BJ1 A;  3QZC A;  3ASN C;  4EBB A;  1GQA A;  4CS8 A;  3F46 A;  4XEV A;  4CDA A;  4LAC B;  2A69 F;  4YK5 A;  4O7G A;  1WWP A;  2HSQ A;  4WAB A;  4XEK A;  4XEF A;  1LIH A;  3O10 A;  4JVS A;  1ZVZ A;  5GPG B;  5L0J A;  1FNT c;  3Q6N A;  4G7O F;  1V4A A;  2LSE A;  1V55 C;  2HV6 A;  4CS9 C;  4E0I A;  2L6H A;  2YQY A;  3NMK A;  3RVY A;  3U3F A;  5JRA A;  4XLN F;  1QSP A;  3S29 A;  2CNW A;  1YVI A;  5A6A A;  2B0H A;  3G4X A;  4LDR A;  4ULV A;  1LPE A;  3HNJ A;  5BQH A;  3ZTM A;  1ZHY A;  4BG0 A;  1A41 A;  2NUT B;  1NG1 A;  4P6I C;  2Q9C A;  1T5O A;  3C7J A;  4RD9 A;  1FMW A;  4U5C E;  5KYW B;  4YT2 A;  1Z63 A;  1T9K A;  4N06 A;  5DS4 A;  4YWQ A;  4YJW A;  1OCO C;  1H7I A;  2EPO A;  4XLP F;  2Y3H A;  3K33 A;  3MX3 A;  4IAQ A;  5BUO A;  3RQE A;  1YAR O;  4WGZ A;  4QI2 A;  1NFN A;  3NG1 A;  5HSW A;  2I15 A;  1HY5 A;  3EGX A;  2G3K A;  3M15 A;  2HUJ A;  2A6H F;  4JE9 A;  3H2U A;  2J9W A;  2YVK A;  3GEE A;  3LEV A;  2W4B A;  3DE9 A;  2XSE A;  4BJ6 A;  4DVY P;  2OOC A;  4EUK B;  2XL8 A;  2IYL D;  1YZC A;  1JOG A;  3OWT A;  1IW7 F;  4U5F E;  5A6B A;  4C3B A;  1D1C A;  2DYS C;  4JZA A;  3T6B A;  1A7V A;  1LE4 A;  3EHM A;  3CEX A;  3CZ6 A;  1PV3 A;  1Y4C A;  3WG7 C;  1HE1 A;  1RKE A;  2LFF A;  3W2W A;  3DWW A;  1D1A A;  1HMO A;  2LK4 A;  4O79 A;  4WJ0 A;  2XRH A;  4GYT A;  2KJG A;  3E9V A;  3ZVR A;  1Z23 A;  2D4U A;  2Y69 C;  2CYD A;  1MMD A;  3QW0 A;  4PJN A;  2CDQ A;  4CJO A;  4CBE A;  1XZQ A;  4PJJ A;  1AUE A;  2AU5 A;  3DM5 A;  1EI7 A;  4EKW A;  5BQI A;  1UFB A;  4JCH A;  1XZP A;  4W8P A;  2R7Q A;  4G7Z F;  2Q4F A;  3SXZ A;  2LQG A;  1SR2 A;  2DI3 A;  3QVY A;  3C18 A;  1VLT A;  3QMK A;  4JW1 A;  4N6C A;  4EBK A;  4FAP B;  4O6Y A;  5E33 A;  4NTF A;  1U0B B;  1W2W A;  3GWL A;  4AE4 B;  2J8W A;  2AVK A;  1ZYR F;  2H7B A;  3BEH A;  1WN0 A;  1VK5 A;  2HJM A;  3FOO A;  3IQ6 A;  4XPY A;  5K0I A;  2AP3 A;  1LE2 A;  3S90 A;  1I4Y A;  1Z6A A;  3C8G B;  3UR3 C;  1VLS A;  1XWJ A;  5AC4 A;  3GM1 A;  4E18 A;  1BZ4 A;  1FMV A;  1U89 A;  3LJB A;  2NG1 A;  4PR9 A;  3NMI A;  3KKB A;  3TUL A;  1Q0G A;  4MTG A;  3UGO A;  1K40 A;  3B71 A;  2OU6 A;  3U5S A;  4JKV A;  2XLO A;  3ZQV A;  1HW1 A;  1CPR A;  4JEB A;  3L8J A;  2VC9 A;  1SYQ A;  4PJL A;  1M6T A;  1RXQ A;  3H2V A;  3FDQ A;  2LCH A;  3MBG A;  4NQF A;  3KMI A;  5L0C A;  1OKK A;  3N24 A;  2HSB A;  4CIH A;  5F5F A;  1MND A;  2HS5 A;  2EPL X;  5KYU A;  2IM8 A;  4RDA A;  1JR8 A;  2NSG A;  2NSF A;  3AG4 C;  3HTK C;  3ZC4 A;  4OIP F;  1FR0 A;  3U9J A;  1RJ9 A;  1E86 A;  2E87 A;  2YL7 A;  1HW2 A;  5B3I A;  2YWA A;  3LS0 A;  1B68 A;  3FOP A;  5KYY B;  1J8M F;  2LFD A;  4H4K C;  1NBB A;  2GFH A;  2H7O A;  3AQB A;  3T4R A;  1OCR C;  2YRF A;  1I5N A;  1MMA A;  3OEO A;  4JEA A;  3A9C A;  2XLD A;  2V26 A;  3KYJ A;  4EWC A;  2R7S A;  3POV A;  4CS7 A;  3TJ5 A;  4HFF B;  4DVZ A;  3C8Z A;  1E84 A;  2WB7 A;  5EHH A;  3S0X A;  1SZI A;  2R7U A;  1ZW2 A;  3EGD B;  4LDQ A;  2HJ3 A;  3BRJ A;  1O3U A;  3U2M A;  3F47 A;  3NKD A;  1MQV A;  3DI5 A;  3UMI A;  3L1M A;  1WAS A;  2WZG A;  1T6Q A;  3Q7L A;  3T9O A;  2KSF A;  2VCA A;  2DB4 A;  2YL0 A;  1OKK D;  1ZU5 A;  3DD7 A;  4UDV A;  4I3M A;  5E2Q A;  2OJQ A;  3S28 A;  3I5Q A;  1HMD A;  1APC A;  3ITF A;  1E83 A;  1DOW A;  3U8P A;  1FFT C;  4DRH B;  5CI8 A;  1N1C A;  5B1A C;  1FAP B;  4WGY A;  4EIY A;  4HEA J;  4OIO F;  1O87 A;  1TWH A;  4U5B E;  1QKR A;  2XS1 A;  2WZF A;  3RQF A;  1Z7Q c;  3UNG C;  4IWB A;  3SZR A;  1M2V A;  2C04 A;  2C03 A;  3LLI A;  4CJG A;  3LNR A;  1F1M A;  4IAR A;  3V5X A;  2ICW G;  1WTY A;  1VB5 A;  1TWG A;  2Y39 A;  2Q3T A;  5B3S C;  2OCC C;  5EGY A;  3H65 A;  1TWA A;  4CDV A;  2L81 A;  1K05 A;  1RMV A;  2PF4 E;  1VMA A;  3EPV A;  4J7Y A;  1E85 A;  2HV7 A;  2A68 F;  1JAF A;  2XM4 A;  2QE9 A;  3UMH A;  4XPW A;  4YT8 A;  1IZM A;  3ZDL A;  4N4W A;  3ZWI A;  5AC5 A;  5KYW A;  1LS4 A;  4MVO A;  4PFO A;  1QZX A;  1M57 C;  2YZS A;  4MTF A;  1K04 A;  3MYF A;  3VAY A;  3J06 A;  4MW3 A;  3JYY A;  3TJ6 A;  4MND A;  1I4Z A;  5T1D B;  4CX9 A;  1BR4 A;  4KNW A;  2L9J A;  1ORJ A;  3JT1 A;  3WOD F;  1CGO A;  2Q9A A;  3JTL O;  3GWN A;  4K0D A;  4G78 A;  2UUI A;  2P7V A;  2P1A A;  4G0H A;  1M2O A;  2YHS A;  3FAP B;  3G50 A;  2HKV A;  3WAQ A;  3LAY A;  4MVZ A;  1C03 A;  4Q5S F;  1ORY A;  2R03 A;  2JD3 A;  3I4U A;  3T6G B;  3O39 A;  2YLG A;  4IJJ A;  4C3D A;  4Q4Z F;  3ATP A;  4JJF A;  5TJ5 E;  1OXB A;  2VB6 A;  1S7Z A;  2R9R B;  4U5D E;  1Z3I X;  1H6G A;  2Q7R A;  1JPJ A;  1TR2 A;  2NPU A;  2VCC A;  4KBL A;  5COG A;  1CGM E;  3DKA A;  2GAQ A;  1TFK B;  3W8I A;  1ZHT A;  3JYH A;  3S27 A;  3AJM A;  1FFH A;  3SXY A;  3ASO C;  1OW6 A;  2B0J A;  2XM0 A;  2J9V A;  3DE8 A;  1VYK A;  3K1H A;  3LES A;  3EH1 A;  4U5E E;  1YYJ A;  3HJC A;  1CPQ A;  4Z9I A;  1EQ1 A;  3VM6 A;  2KGO A;  2H8A A;  4MVM A;  4P9F A;  1G5Z A;  2X0C A;  4AX2 A;  4EBJ A;  2OEV A;  1Q0D A;  3W2V A;  1A0B A;  2D5R B;  4BJ6 C;  1A7D A;  1ZU4 A;  2LD6 A;  5KYX B;  3B0U X;  5L0G A;  1NU7 D;  1UG7 A;  2YEV A;  2XXA A;  2F22 A;  5DS6 A;  3ZSU A;  3EGX B;  3WHN A;  4NC3 A;  4AE4 A;  3LS1 A;  5L0F A;  1R4T A;  5DQZ A;  1WOL A;  2JPU A;  2YKZ A;  3HNK A;  1Q0M A;  4MW8 A;  1JMW A;  2M64 A;  2ZXR A;  3C8G A;  1MMG A;  1EA8 A;  3RW0 A;  3VF0 A;  2PX0 A;  2XLE A;  3ABM C;  3X2Q C;  2CCY A;  3FMS A;  5F28 E;  4G7H F;  5FZT A;  3E70 C;  2PNO A;  3DAG A;  5CI9 A;  2ETS A;  3I5P A;  2R7O A;  4OD4 A;  5D92 A;  4B6I A;  5T3T A;  4CSA C;  1FTS A;  3MFN A;  4IAO A;  4D4X A;  3ZQY A;  2P0N A;  5A6K A;  5F5H A;  3DXJ F;  5COM A;  3DMD A;  1ZHX A;  3Q6M A;  2WVO A;  2BC5 A;  2WZL A;  1V74 B;  4YT5 A;  2EIM C;  2QY9 A;  2TMV P;  2BL2 A;  4JUR I;  3QW1 A;  2IXN A;  3FAJ A;  2MHR A;  3IPM O;  2VCB A;  1LS1 A;  2MWQ A;  4PFP A;  3C62 A;  2PBE A;  2CGE A;  3O55 A;  3TK0 A;  1ZZP A;  2FAP B;  1H9G A;  4C7O B;  4CSA A;  1NSG B;  5KYY A;  2IOQ A;  3C8G D;  3IQC A;  3K66 A;  1ZHW A;  2XS8 A;  3OA1 A;  4P9T A;  3X1O A;  4OIQ F;  3SEO A;  3IHU A;  5E3A A;  4RBN A;  4Q7C A;  3AG3 C;  1R5I D;  2Q9B A;  3JSE O;  3TD7 A;  3U0C A;  2NUP B;  3W4Y A;  4OD5 A;  2Y3D A;  2KW3 C;  4CIP A;  1OW8 A;  3EGD A;  3SP1 A;  1D1B A;  3RIP A;  4NCQ A;  3M79 A;  3N0T A;  2CW0 F;  4MS2 A;  3EFO B;  4MVS A;  1AEP A;  3JCU Q;  1QQ3 A;  4FES A;  3EG9 B;  4YL1 A;  4Z9H A;  4FX5 A;  1VOM A;  4J30 B;  3GEI A;  4LER A;  1T6I A;  1YLM A;  3U8V A;  3NKE A;  4JTC B;  5L3V A;  1EKY A;  4MTO A;  5DQT A;  2LIG A;  5KYU B;  1V54 C;  2J9U A;  5KYN A;  2IXP A;  4XPX A;  2GDC A;  3LUT B;  1YYX A;  3GM3 A;  4YN0 B;  2XLV A;  4KC9 A;  4XWJ A;  3K1I A;  2R7T A;  3M1C B;  2X51 A;  1O5H A;  1GS9 A;  2L6G A;  3FXH A;  3RVZ A;  3KL4 A;  4BJ5 A;  4U9E A;  2R7X A;  1PD0 A;  3AGU A;  2HZ8 A;  3NYJ A;  1SF8 A;  4ER9 A;  4U9D A;  4R32 A;  1JPN A;  3M4B A;  1LI7 A;  3JSZ A;  3L8I A;  3PCV A;  2HFI A;  1MMN A;  1D0Y A;  1QLE C;  3K7D A;  2YL1 A;  2G62 A;  3DJU B;  1TQG A;  5E3C A;  1ZHZ A;  2A0U A;  2QNL A;  2EIN C;  5B1B C;  2EPN A;  3B9Q A;  4JC7 A;  2IBF A;  4O6M A;  4ULW A;  1SMY F;  2ZD9 A;  1L3P A;  3RQG A;  3ZIB A;  1H9T A;  3NMJ A;  3B29 A;  4YL0 A;  3T6J A;  1WGW A;  2QLA A;  4CS8 C;  1OR2 A;  3EZH A;  2Y3B A;  2FFH A;  2ZPA A;  4DBR A;  2QTV A;  3U3B A;  1YDI A;  4CS9 A;  5JLI A;  5DVW A;  3AGT A;  1HE9 A;  3MYI A;  4U5G A;  3V7O A;  3ZG1 A;  4BEJ A;  2NUT A;  1GM5 A;  2KC3 A;  5D91 A;  3RYL A;  5L0H A;  1NFO A;  5CIV A;  5BQG A;  3KH2 A;  2J0X A;  1OXK A;  4NTA A;  2HMQ A;  1G4U S;  1U6H A;  1ORS C;  2Y3G A;  4DJ9 A;  1G4W R;  3TOM A;  5JUA A;  4JTD B;  1OCC C;  1M2V B;  2A6E F;  2A0B A;  2MYS A;  1C02 A;  3NYM A;  1BR2 A;  1C17 M;  1JRA A;  4H54 A;  4LDK A;  1NLX A;  3HNL A;  1M56 C;  3N2Z B;  1PD1 A;  3EZI A;  3R7C A;  5JT4 A;  3C63 A;  3SNH A;  2R02 A;  1D0Z A;  4A4A A;  4C3E A;  1E2X A;  2J46 A;  2JX0 A;  2R25 A;  2J45 A;  2J7P A;  2WL8 A;  1YZA A;  3S84 A;  2OJE D;  4NY3 A;  4YT4 A;  3ABL C;  4NTB A;  3UGP A;  1TFO B;  256B A;  4E0H A;  3FVY A;  2RSE B;  2ZXO A;  4JRZ A;  1G8X A;  5A6J A;  4AL1 A;  2YLD A;  4ZLD A;  1CGN A;  4DRJ B;  3HNI A;  4HE8 D;  3V5Y A;  1ST6 A;  1YAU O;  4L6R A;  5AGF A;  4OIN F;  4I44 A;  5A69 A;  4MVR A;  4QI0 A;  2R05 A;  3UMK A;  4IRU A;  1Q0K A;  4LLE A;  4XTK A;  4BJT A;  4Z9J A;  3V5Z A;  4KNV A;  1LKX A;  3ZTZ A;  2J9B A;  3B0P A;  2BE5 F;  3DAF A;  1QVX A;  5KYX A;  3ABK C;  3QVZ A;  4AL0 A;  1OW7 A;  1VYI A;  4JCZ A;  1YJG A;  1LM3 B;  3AOU A;  4HFK B;  1Z5Z A;  2O9X A;  5DLJ A;  3FHD A;  1BDJ B;  2XLM A;  4FWV A;  4CDY A;  2R7W A;  3B0V C;  5JVE A;  3GOR A;  3EHN A;  4PAC A;  3O6X A;  3TQO A;  2XLW A;  2J7P D;  2UUH A;  4QDL A;  3M4C A;  2KNH A;  2CNW D;  3AG2 C;  3RH3 A;  4AK9 A;  2RD9 A;  1OQC A;  3US6 A;  3VRC A;  5IY5 C;  5L3Q A; 
#chains in the Genus database with same CATH homology
 4DRJ B;  1NSG B;  2GAQ A;  3FAP B;  1AUE A;  4DRH B;  5GPG B;  4DRI B;  1FAP B;  2RSE B;  2NPU A;  2FAP B;  4FAP B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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