4DRJB

O-crystal structure of the ppiase domain of fkbp52, rapamycin and the frb fragment of mtor
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
96
structure length
96
Chain Sequence
MDPEFMEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Isomerase/transferase
molecule keywords Peptidyl-prolyl cis-trans isomerase FKBP4
total genus 40
structure length 96
sequence length 96
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2012-02-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.150 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) FKBP12-rapamycin binding domain 4drjB00
2FAPB 4FAPB 5GPGB 4DRIB 4DRHB 2NPUA 1FAPB 3FAPB 1AUEA 1NSGB 4DRJB 2RSEB 2GAQA
chains in the Genus database with same CATH superfamily
4I44A 3POVA 2Y3HA 3ABKC 1T6IA 1YARO 3LAYA 2J46A 3U3FA 2J9UA 3NYLA 3JYHA 4CS9A 2FFHA 1VTMP 1YAUO 5JVEA 2XL8A 1BR4A 2JD3A 2EPLX 5A6BA 4P9FA 2GDCA 3HNJA 2LIGA 5D91A 4O7GA 1GS9A 3E70C 4JVSA 1D1CA 2WZFA 3V5YA 3U9JA 2XXAA 2HKVA 2J9VA 4KC9A 3T9OA 2QTVA 3GANA 4YT5A 4PACA 4LDKA 1WATA 2GFHA 2LD6A 2XLVA 3TOLA 2EPMX 2FAPB 2H7VC 3B9QA 4CS8C 3AGTA 4FWVA 3Q6MA 4EUKB 4MNDA 1JPJA 1PD1A 2ASRA 2EILC 2XL6A 4AE4A 5A6AA 3EGXA 3M1CB 3ASOC 2YLGA 3MBGA 1JRAA 2XLMA 1JAFA 1PD0A 2L6HA 1M57C 3B0VC 2OJED 3C8GA 4Q7CA 3RFYA 3B0UX 3ZSUA 4MTOA 2IXNA 3LUTB 3SYNA 3TULA 3LS1A 4CSAC 2AU5A 2YLDA 4JRZA 4IGGA 1JOGA 3GWLA 1M2VB 2IYLD 3C8GD 4EWCA 4G7OF 1QZXA 1BR1A 2WL8A 1KTMA 2VCCA 1YDIA 4J32B 3QW0A 1C03A 1QVXA 1R5ID 1TWAA 2KNHA 3V5XA 2DGJA 1ST6A 4JJGA 3WHNA 3LEVA 4MVMA 4CDVA 3VM6A 3DJUB 4Z9JA 4AL0A 3K1IC 3LEOA 2H7OA 3JT1A 5L3QA 2YHSA 4PFOA 3FVYA 3JRTA 1V54C 2KC3A 5COFA 2R7RA 2XLDA 2VCBA 3AQCA 3S90A 1SZIA 2XLHA 1E86A 3LNRA 4KBLA 2X51A 3O55A 1Y4CA 4G7HF 3EG9A 3RH3A 1WOLA 1O5HA 4Q4ZF 4I1OB 1GM5A 2D5RB 4P9TA 1ZZPA 3TD7A 2EINC 5A69A 4U5EE 3RQGA 1T6QA 1OKKA 3O6XA 2LK4A 4R32A 4BEJA 5KYYA 3PHF2 2XSEA 1WTYA 4U5DE 5E2QA 5KYUA 3IPMO 1Q0DA 2ZXWC 3JSZA 3K1IA 3L1MA 5HSWA 4CX9A 2WVNA 1NU9C 2NSGA 4CS7A 4IJJA 1ORJA 5TJ5E 3AQBA 5AC5A 1A7VA 3ECSA 3N24A 3AG2C 3NKDA 3SEOA 2BL2A 3O10A 5DS4A 3DE8A 1SF8A 4MVRA 5K0IA 1FTSA 2LFFA 1D0YA 1I4ZA 1ZHXA 3LS0A 3UR3C 1KNYA 1YLMA 2QUPA 4O79A 2YLIA 2OEVA 2O9XA 3CQZA 2PX3A 2WB7A 3H2VA 2J9WA 2MWQA 4P6IC 3KMIA 4FX5A 2DB4A 5F28E 5L0HA 3ABMC 3FAJA 3ZTZA 2KSFA 5D92A 2HV7A 3UMKA 3WODF 5JRAA 1OCCC 2L6GA 3QZCA 3M4CA 4H54A 2F22A 4DVZA 3FDQA 1Y6DA 2YRFA 4HEAJ 1D1AA 4H4KC 1OXBA 3MYIA 5JUAA 1EA8A 1ZHZA 2XS1A 2IXOA 3B29A 3RYLA 1FR0A 5T3TA 2CCYA 1T5OA 3DM5A 4OIOF 3EZHA 4BJTA 1PV3A 3DWWA 3LLIA 4MVOA 3ZDLA 5FZTA 4XEFA 2PFDA 5L0JA 2R02A 3GORA 3U8PA 1GQAA 3UMHA 1FMWA 1L3PA 3B0PA 5L0IA 1OW7A 4I1MA 1VK5A 4PJMA 3RF3A 2WVQA 3X1OA 2NUPA 1VYIA 2Q7RA 1RMVA 3GWNA 2XLEA 1D0XA 3HNKA 2CNWA 1RJ9B 1W2WA 2RSEB 4XPXA 5JP7A 2M64A 2VC9A 1YA9A 2Q3TA 3I5PA 1IZMA 4M63A 2J0XA 3PDMP 2R03A 2W9YA 2XLOA 4LDRA 1Q0MA 1LE4A 1DOWA 1L7CA 2A0UA 1I4YA 1RXQA 2HV6A 2Y3BA 3EJNA 4G78A 3WG7C 2EPKX 5DQTA 3S27A 2VCAA 3AGUA 4E18A 5E3CA 1Z6AA 1OCOC 2A0BA 3IQCA 3Q7GA 3F47A 2LFDA 1MQVA 3I4UA 2Y69C 3L34A 4DRIB 4YWQA 1NBBA 4F4BA 3EFOB 2R7TA 3CZ6A 3RQEA 4A2NB 1MNDA 2LQGA 4RBNA 4XLPF 2OU6A 3LESA 5BQGA 3RVZA 5KYXA 1JMWA 4O6YA 4MW3A 2R7QA 1V4AA 2XLWA 3L0IA 4PFPA 3UMIA 3PMRA 2DYSC 4PJLA 1PCXA 1OXKA 1CPRA 1GGQA 1SMYF 3FOPA 1QLEC 2Q00A 2PF4E 2GWWA 1AEPA 4CSAA 3HLZA 3K1HA 4WJ0A 2KYHA 5T3WA 3EHMA 4G7ZF 1E83A 4QDLA 4XWJA 2AP3A 1RJ9A 2R7UA 4U5CE 1Q0KA 2CW0F 4ULVA 4JTCB 1TWGA 2Y3DA 1WASA 4FESA 4ER9A 4FAPB 2VH3A 4ONSA 3JSEO 4YL3A 3SXZA 4D4XA 3GEHA 4BPMA 3SNHA 5AC4A 4RDAA 4BJ6A 3EH1A 5E3AA 4YT4A 3G4ZA 2H8AA 4UDVA 3R7CA 1CGME 1BBHA 1Z23A 1VMAA 3FMSA 4NTAA 3SXYA 1LI7A 4JURI 1CGOA 1M2VA 2VB6A 5L0FA 1B68A 3FOOA 1YZCA 4YL1A 2YQYA 3ZIBA 4CJOA 2G3KA 3KYIA 3JYYA 1D1BA 1FNTc 1HW2A 1O3UA 3DE9A 2YL0A 4KNWA 2ZXOA 3DKAA 1YVIA 4EIYA 1Q0GA 4DXWA 4WGYA 1M2OA 4HFFB 4J7YA 3CEXA 1AUEA 3JRMO 4K1OA 1A7EA 3HNLA 3RIPA 3C8GB 3FHDA 3H2UA 4MQ9F 3U8VA 5CIVA 3DAGA 3NRHA 4YT2A 4JC7A 4JW1A 2LSEA 5BQHA 5FCLA 3VF0A 4ZLCA 3V7OA 5JT4A 3FAPB 2J8WA 1U6HA 2KJGA 3RVYA 3BEHA 4U9EA 3N0TA 2A68F 1V74B 2HMQA 5IY5C 3AG4C 2E87A 3Q7LA 3HJCA 4JKVA 4WABA 5BUOA 5L0CA 5B1BC 1VYKA 1Z5ZA 3ZQYA 2YL3A 2YWAA 3C62A 4N4WA 3IHUA 3OA1A 3NKEA 1M56C 2NPUA 2P1AA 4OINF 3T6JA 3U9MA 3SXKA 4CBEA 5KYYB 1U0BB 2GAQA 2J0WA 1K40A 1MMNA 4IAOA 4JZAA 4BJ5A 2P7VA 3U0CA 1E84A 4NY3A 1I5NA 2XXAB 3M15A 5CI9A 3ZQVA 1O87A 4E17A 1G8XA 1NSGB 3CSKA 2IBFA 1APCA 3ZTMA 2CYDA 2KK1A 4YT8A 2Z15A 2LCHA 4JTAB 1SYQA 1A41A 3IQTA 4U5HA 4U5BE 3EH2A 2ETSA 4CS9C 4BJ1A 2IXPA 2B0HA 4DOZA 3DJNB 4MW8A 4IWBA 4IAQA 2EPNA 1M6TA 2AWCA 4MVUA 1QKRA 3GM2A 3W4YA 5L0GA 1LI5A 5B3IA 3DXJF 1WGWA 2G3VA 2NSFA 3QW1A 3DAFA 3AJMA 2OKUA 4CDAA 1E2XA 1RKCA 1EKYA 2HFIA 1LVKA 4OIQF 4U5FE 5JSLA 2OG2A 3K7DA 3Q6NA 4LLEA 1SR2A 4QI2A 1VLTA 2HJMA 2R7WA 4YL0A 3G50A 1C17M 1ZYRF 2TMVP 2Q9CA 1OW6A 4O6NA 3VRCA 3K6BA 1E85A 3LJBA 5B1AC 4LDQA 4J7TA 5L0DA 1RKEA 4KNVA 4YN0B 1LM3B 1LS4A 2Q9BA 4JIOA 1R4TA 3HNIA 3VAYA 1UG7A 3O39A 4EKWA 2XRHA 3JTLO 2QLAA 3IQ6A 2PP4A 4U5GA 1TWCA 3UNGC 4IB4A 4NC3A 2YL1A 3QMKA 3MLGA 3U3BA 1Z7Qc 1F1MA 2B0JA 3QTHA 2DI3A 4C3EA 3M4BA 5EHHA 3DZAA 3RW0A 2JX0A 3DD7A 4K0DA 4W8PA 5B3SC 1CPQA 2YEVA 2G62A 3NMJA 1TR2A 3OEOA 3US6A 1HMOA 3I5QA 3X2QC 2WZLA 4MTFA 1RCPA 1YZAA 1YYXA 1BDJB 1H6GA 1UFBA 4C7OA 2MHRA 2J45A 1ZHTA 4HFKB 1HE9A 4C3BA 5JLIA 2OCCC 1OR3A 2A6EF 2UUIA 2P61A 4JJFA 2V26A 4BJ6C 5KYNA 3A11A 1TQGA 2A69F 3U2MA 5KYWB 1TWHA 2NG1A 3C63A 3DI5A 2IOQA 4C3DA 4XPYA 2W4MA 4Z9IA 3GM1A 4A4AA 1J8MF 2UUHA 1TFKB 1FMVA 4EBKA 4PJJA 1Q0FA 4AL1A 2GA0A 3MX3A 3TJ6A 2BC5A 2OQMA 2KW3C 4MTGA 3TK0A 3U5SA 2HJ3A 3S84A 3KYJA 2H7BA 4ULWA 5DQZA 5EGYA 2CGEA 4N06A 1QQ3A 3KH2A 3L8JA 4HE8D 2ZPAA 1TFOB 1RKEB 5KYXB 4QI0A 4MVSA 1IW7F 1K04A 1MNEA 4JCHA 1DOVA 4OIPF 1LPEA 4L6RA 3TJ5A 4DBRA 4XEKA 1MMGA 5A6JA 3W2VA 2I8BA 3RQFA 4EBBA 4OIRF 2EIJC 5KYUB 4JCZA 4MVZA 1NFNA 3W2WA 2NUPB 4J30B 2W4BA 4X0RA 4C7OB 2A6HF 4N6CA 3W8HA 1C02A 2HSQA 1BR2A 1G4WR 1ORYA 1S05A 1ZHWA 1WWPA 3PCVA 4B6IA 3S0XA 1ZU4A 4Q5SF 2OOCA 3F46A 2V3CC 4KI2A 3M79A 4CIHA 3J06A 2NUTA 1HE1A 4NTBA 3EPVA 1BZ4A 3ZC4A 3H65A 1NLXA 3B71A 1LIHA 2R7SA 3N2ZB 4I3MA 3QVZA 1EI7A 1K05A 4O6MA 4DRHB 1OR2A 2XM0A 3GODA 4LLCA 2Y3GA 4CDYA 1Z63A 4ANJA 3NG1A 1QSPA 2OEXA 1A0BA 3ABLC 3GEEA 3EZIA 1A7DA 4DBQA 1FAPB 5DS5A 1ZW2A 2L81A 4XEVA 1T6UA 2Y39A 4JTDB 4DRJB 2W45A 2R25A 4CS8A 2BE5F 2XS8A 3ZWIA 4BEMJ 1ZU5A 2YKZA 1XZQA 1ZHYA 2HZ8A 1FFTC 3CAXA 4MVQA 1ZW3A 3ZG1A 1EQ1A 2D4UA 2X0CA 2EIMC 256BA 4LACB 4YJWA 4CJGA 2MYSA 1ORSC 3AOUA 1OCZC 5BQIA 2HUJA 4XPWA 1H9TA 3K33A 5F5HA 2L9JA 2ZXRA 3GM3A 4MS2A 5DS6A 1JPNA 3A9CA 1Z3IX 4IARA 4JEBA 3WAQA 2DYRC 1CGNA 1OKKD 2QNLA 3U2LA 1NG1A 2R05A 3EQLF 3ATPA 2OJQA 3JZ0A 3LNMB 4GEHA 4W8KA 4AE4B 4YK5A 4E0IA 1HY5A 4GYTA 3NDBB 1XWJA 1XZPA 2ICWG 4NCQA 2WZGA 4E7SA 3OWTA 4JEAA 1VB5A 1FFHA 3L8IA 3MYFA 4PJNA 1HW1A 1D0ZA 2PBEA 2XM4A 1S7ZA 4PR9A 2AWYA 1LKXA 2ZD9A 3TQOA 4CIPA 1J8YF 3E9VA 4LERA 2KQ9A 3IEEA 4WGZA 4DVYP 1AVOB 4OD4A 4D4NA 1MMAA 2QE9A 5DVWA 4ZLDA 5HV9A 2J9BA 3T6GB 3ITFA 4JE9A 3HTKC 3C8ZA 4N6HA 2R7XA 3T6BA 1V55C 2IM8A 4RD9A 3HKKA 1KU2A 2AVKA 5E33A 4U9DA 3S28A 2L7AA 3KPHA 4BG0A 4E7ZA 2NUTB 3C18A 1TKNA 2R9RB 2EPOA 5COGA 3SZRA 1H7IA 2KGOA 2M4EA 1MMDA 1VOMA 3IQ5A 2VASA 4GQHA 2PX0A 1OQCA 5GPGB 2HS5A 4BJ5C 2CDQA 2A1DD 1WN0A 4XQ1A 1YJGA 3EGDA 4DJ9A 2YZSA 3C7JA 3MFNA 1NU7D 1ZVZA 3JCUQ 3EHNA 3NYJA 2IXMA 5EK0A 3RKOF 2YL7A 4PK4A 2PNOA 2FGYA 1LE2A 1JR8A 3BRJA 5F5FA 3QVYA 2CNWD 2HSBA 3GEIA 1U89A 3EGXB 4AX2A 2LP4A 1OW8A 3LLKA 3S29A 2P6VA 2ZXPA 2R7OA 3K66A 3KL4A 2Q9AA 3EFOA 1G5ZA 3KKBA 3R2PA 3T4RA 4Z9HA 5A6BD 5DLJA 1HMDA 3NYMA 3UGPA 4XLNF 2R7VA 5JS5A 2Q4FA 3DM9B 4XTKA 1T01A 3AG1C 3EGDB 1NZEA 1N1CA 5AGFA 4AK9A 1YYJA 3V5ZA 3SXMA 4EBJA 1G4US 3SP1A 2C03A 2I15A 3W8IA 2J7PD 4G0HA 1H9GA 4IRUA 5COMA 2RD9A 3ASNC 5KYWA 3NMIA 3UGOA 2C04A 3G4XA 2XL4A 2EIKC 5CI8A 5T1DB 1YA7O 4K7BA 4NTFA 3TOMA 4EHPA 3ZVRA 3NMKA 1QPUA 1NFOA 1VLSA 2WVOA 3EG9B 2JPUA 5L3VA 2QY9A 4NQFA 2P0NA 4OD5A 1LS1A 2YVKA 4E0HA 3FXHA 1T9KA 2L6FA 3AG3C 3S9OA 5A6KA 2J7PA 3VYWA 2HMZA 1OCRC 3DMDA
chains in the Genus database with same CATH topology
2FAPB 4FAPB 5GPGB 4DRIB 4DRHB 2NPUA 1FAPB 3FAPB 1AUEA 1NSGB 4DRJB 2RSEB 2GAQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FAP B;  4FAP B;  5GPG B;  4DRI B;  4DRH B;  2NPU A;  1FAP B;  3FAP B;  1AUE A;  1NSG B;  4DRJ B;  2RSE B;  2GAQ A; 
#chains in the Genus database with same CATH topology
 4I44 A;  3POV A;  2Y3H A;  3ABK C;  1T6I A;  1YAR O;  3LAY A;  2J46 A;  3U3F A;  2J9U A;  3NYL A;  3JYH A;  4CS9 A;  2FFH A;  1VTM P;  1YAU O;  5JVE A;  2XL8 A;  1BR4 A;  2JD3 A;  2EPL X;  5A6B A;  4P9F A;  2GDC A;  3HNJ A;  2LIG A;  5D91 A;  4O7G A;  1GS9 A;  3E70 C;  4JVS A;  1D1C A;  2WZF A;  3V5Y A;  3U9J A;  2XXA A;  2HKV A;  2J9V A;  4KC9 A;  3T9O A;  2QTV A;  3GAN A;  4YT5 A;  4PAC A;  4LDK A;  1WAT A;  2GFH A;  2LD6 A;  2XLV A;  3TOL A;  2EPM X;  2FAP B;  2H7V C;  3B9Q A;  4CS8 C;  3AGT A;  4FWV A;  3Q6M A;  4EUK B;  4MND A;  1JPJ A;  1PD1 A;  2ASR A;  2EIL C;  2XL6 A;  4AE4 A;  5A6A A;  3EGX A;  3M1C B;  3ASO C;  2YLG A;  3MBG A;  1JRA A;  2XLM A;  1JAF A;  1PD0 A;  2L6H A;  1M57 C;  3B0V C;  2OJE D;  3C8G A;  4Q7C A;  3RFY A;  3B0U X;  3ZSU A;  4MTO A;  2IXN A;  3LUT B;  3SYN A;  3TUL A;  3LS1 A;  4CSA C;  2AU5 A;  2YLD A;  4JRZ A;  4IGG A;  1JOG A;  3GWL A;  1M2V B;  2IYL D;  3C8G D;  4EWC A;  4G7O F;  1QZX A;  1BR1 A;  2WL8 A;  1KTM A;  2VCC A;  1YDI A;  4J32 B;  3QW0 A;  1C03 A;  1QVX A;  1R5I D;  1TWA A;  2KNH A;  3V5X A;  2DGJ A;  1ST6 A;  4JJG A;  3WHN A;  3LEV A;  4MVM A;  4CDV A;  3VM6 A;  3DJU B;  4Z9J A;  4AL0 A;  3K1I C;  3LEO A;  2H7O A;  3JT1 A;  5L3Q A;  2YHS A;  4PFO A;  3FVY A;  3JRT A;  1V54 C;  2KC3 A;  5COF A;  2R7R A;  2XLD A;  2VCB A;  3AQC A;  3S90 A;  1SZI A;  2XLH A;  1E86 A;  3LNR A;  4KBL A;  2X51 A;  3O55 A;  1Y4C A;  4G7H F;  3EG9 A;  3RH3 A;  1WOL A;  1O5H A;  4Q4Z F;  4I1O B;  1GM5 A;  2D5R B;  4P9T A;  1ZZP A;  3TD7 A;  2EIN C;  5A69 A;  4U5E E;  3RQG A;  1T6Q A;  1OKK A;  3O6X A;  2LK4 A;  4R32 A;  4BEJ A;  5KYY A;  3PHF 2;  2XSE A;  1WTY A;  4U5D E;  5E2Q A;  5KYU A;  3IPM O;  1Q0D A;  2ZXW C;  3JSZ A;  3K1I A;  3L1M A;  5HSW A;  4CX9 A;  2WVN A;  1NU9 C;  2NSG A;  4CS7 A;  4IJJ A;  1ORJ A;  5TJ5 E;  3AQB A;  5AC5 A;  1A7V A;  3ECS A;  3N24 A;  3AG2 C;  3NKD A;  3SEO A;  2BL2 A;  3O10 A;  5DS4 A;  3DE8 A;  1SF8 A;  4MVR A;  5K0I A;  1FTS A;  2LFF A;  1D0Y A;  1I4Z A;  1ZHX A;  3LS0 A;  3UR3 C;  1KNY A;  1YLM A;  2QUP A;  4O79 A;  2YLI A;  2OEV A;  2O9X A;  3CQZ A;  2PX3 A;  2WB7 A;  3H2V A;  2J9W A;  2MWQ A;  4P6I C;  3KMI A;  4FX5 A;  2DB4 A;  5F28 E;  5L0H A;  3ABM C;  3FAJ A;  3ZTZ A;  2KSF A;  5D92 A;  2HV7 A;  3UMK A;  3WOD F;  5JRA A;  1OCC C;  2L6G A;  3QZC A;  3M4C A;  4H54 A;  2F22 A;  4DVZ A;  3FDQ A;  1Y6D A;  2YRF A;  4HEA J;  1D1A A;  4H4K C;  1OXB A;  3MYI A;  5JUA A;  1EA8 A;  1ZHZ A;  2XS1 A;  2IXO A;  3B29 A;  3RYL A;  1FR0 A;  5T3T A;  2CCY A;  1T5O A;  3DM5 A;  4OIO F;  3EZH A;  4BJT A;  1PV3 A;  3DWW A;  3LLI A;  4MVO A;  3ZDL A;  5FZT A;  4XEF A;  2PFD A;  5L0J A;  2R02 A;  3GOR A;  3U8P A;  1GQA A;  3UMH A;  1FMW A;  1L3P A;  3B0P A;  5L0I A;  1OW7 A;  4I1M A;  1VK5 A;  4PJM A;  3RF3 A;  2WVQ A;  3X1O A;  2NUP A;  1VYI A;  2Q7R A;  1RMV A;  3GWN A;  2XLE A;  1D0X A;  3HNK A;  2CNW A;  1RJ9 B;  1W2W A;  2RSE B;  4XPX A;  5JP7 A;  2M64 A;  2VC9 A;  1YA9 A;  2Q3T A;  3I5P A;  1IZM A;  4M63 A;  2J0X A;  3PDM P;  2R03 A;  2W9Y A;  2XLO A;  4LDR A;  1Q0M A;  1LE4 A;  1DOW A;  1L7C A;  2A0U A;  1I4Y A;  1RXQ A;  2HV6 A;  2Y3B A;  3EJN A;  4G78 A;  3WG7 C;  2EPK X;  5DQT A;  3S27 A;  2VCA A;  3AGU A;  4E18 A;  5E3C A;  1Z6A A;  1OCO C;  2A0B A;  3IQC A;  3Q7G A;  3F47 A;  2LFD A;  1MQV A;  3I4U A;  2Y69 C;  3L34 A;  4DRI B;  4YWQ A;  1NBB A;  4F4B A;  3EFO B;  2R7T A;  3CZ6 A;  3RQE A;  4A2N B;  1MND A;  2LQG A;  4RBN A;  4XLP F;  2OU6 A;  3LES A;  5BQG A;  3RVZ A;  5KYX A;  1JMW A;  4O6Y A;  4MW3 A;  2R7Q A;  1V4A A;  2XLW A;  3L0I A;  4PFP A;  3UMI A;  3PMR A;  2DYS C;  4PJL A;  1PCX A;  1OXK A;  1CPR A;  1GGQ A;  1SMY F;  3FOP A;  1QLE C;  2Q00 A;  2PF4 E;  2GWW A;  1AEP A;  4CSA A;  3HLZ A;  3K1H A;  4WJ0 A;  2KYH A;  5T3W A;  3EHM A;  4G7Z F;  1E83 A;  4QDL A;  4XWJ A;  2AP3 A;  1RJ9 A;  2R7U A;  4U5C E;  1Q0K A;  2CW0 F;  4ULV A;  4JTC B;  1TWG A;  2Y3D A;  1WAS A;  4FES A;  4ER9 A;  4FAP B;  2VH3 A;  4ONS A;  3JSE O;  4YL3 A;  3SXZ A;  4D4X A;  3GEH A;  4BPM A;  3SNH A;  5AC4 A;  4RDA A;  4BJ6 A;  3EH1 A;  5E3A A;  4YT4 A;  3G4Z A;  2H8A A;  4UDV A;  3R7C A;  1CGM E;  1BBH A;  1Z23 A;  1VMA A;  3FMS A;  4NTA A;  3SXY A;  1LI7 A;  4JUR I;  1CGO A;  1M2V A;  2VB6 A;  5L0F A;  1B68 A;  3FOO A;  1YZC A;  4YL1 A;  2YQY A;  3ZIB A;  4CJO A;  2G3K A;  3KYI A;  3JYY A;  1D1B A;  1FNT c;  1HW2 A;  1O3U A;  3DE9 A;  2YL0 A;  4KNW A;  2ZXO A;  3DKA A;  1YVI A;  4EIY A;  1Q0G A;  4DXW A;  4WGY A;  1M2O A;  4HFF B;  4J7Y A;  3CEX A;  1AUE A;  3JRM O;  4K1O A;  1A7E A;  3HNL A;  3RIP A;  3C8G B;  3FHD A;  3H2U A;  4MQ9 F;  3U8V A;  5CIV A;  3DAG A;  3NRH A;  4YT2 A;  4JC7 A;  4JW1 A;  2LSE A;  5BQH A;  5FCL A;  3VF0 A;  4ZLC A;  3V7O A;  5JT4 A;  3FAP B;  2J8W A;  1U6H A;  2KJG A;  3RVY A;  3BEH A;  4U9E A;  3N0T A;  2A68 F;  1V74 B;  2HMQ A;  5IY5 C;  3AG4 C;  2E87 A;  3Q7L A;  3HJC A;  4JKV A;  4WAB A;  5BUO A;  5L0C A;  5B1B C;  1VYK A;  1Z5Z A;  3ZQY A;  2YL3 A;  2YWA A;  3C62 A;  4N4W A;  3IHU A;  3OA1 A;  3NKE A;  1M56 C;  2NPU A;  2P1A A;  4OIN F;  3T6J A;  3U9M A;  3SXK A;  4CBE A;  5KYY B;  1U0B B;  2GAQ A;  2J0W A;  1K40 A;  1MMN A;  4IAO A;  4JZA A;  4BJ5 A;  2P7V A;  3U0C A;  1E84 A;  4NY3 A;  1I5N A;  2XXA B;  3M15 A;  5CI9 A;  3ZQV A;  1O87 A;  4E17 A;  1G8X A;  1NSG B;  3CSK A;  2IBF A;  1APC A;  3ZTM A;  2CYD A;  2KK1 A;  4YT8 A;  2Z15 A;  2LCH A;  4JTA B;  1SYQ A;  1A41 A;  3IQT A;  4U5H A;  4U5B E;  3EH2 A;  2ETS A;  4CS9 C;  4BJ1 A;  2IXP A;  2B0H A;  4DOZ A;  3DJN B;  4MW8 A;  4IWB A;  4IAQ A;  2EPN A;  1M6T A;  2AWC A;  4MVU A;  1QKR A;  3GM2 A;  3W4Y A;  5L0G A;  1LI5 A;  5B3I A;  3DXJ F;  1WGW A;  2G3V A;  2NSF A;  3QW1 A;  3DAF A;  3AJM A;  2OKU A;  4CDA A;  1E2X A;  1RKC A;  1EKY A;  2HFI A;  1LVK A;  4OIQ F;  4U5F E;  5JSL A;  2OG2 A;  3K7D A;  3Q6N A;  4LLE A;  1SR2 A;  4QI2 A;  1VLT A;  2HJM A;  2R7W A;  4YL0 A;  3G50 A;  1C17 M;  1ZYR F;  2TMV P;  2Q9C A;  1OW6 A;  4O6N A;  3VRC A;  3K6B A;  1E85 A;  3LJB A;  5B1A C;  4LDQ A;  4J7T A;  5L0D A;  1RKE A;  4KNV A;  4YN0 B;  1LM3 B;  1LS4 A;  2Q9B A;  4JIO A;  1R4T A;  3HNI A;  3VAY A;  1UG7 A;  3O39 A;  4EKW A;  2XRH A;  3JTL O;  2QLA A;  3IQ6 A;  2PP4 A;  4U5G A;  1TWC A;  3UNG C;  4IB4 A;  4NC3 A;  2YL1 A;  3QMK A;  3MLG A;  3U3B A;  1Z7Q c;  1F1M A;  2B0J A;  3QTH A;  2DI3 A;  4C3E A;  3M4B A;  5EHH A;  3DZA A;  3RW0 A;  2JX0 A;  3DD7 A;  4K0D A;  4W8P A;  5B3S C;  1CPQ A;  2YEV A;  2G62 A;  3NMJ A;  1TR2 A;  3OEO A;  3US6 A;  1HMO A;  3I5Q A;  3X2Q C;  2WZL A;  4MTF A;  1RCP A;  1YZA A;  1YYX A;  1BDJ B;  1H6G A;  1UFB A;  4C7O A;  2MHR A;  2J45 A;  1ZHT A;  4HFK B;  1HE9 A;  4C3B A;  5JLI A;  2OCC C;  1OR3 A;  2A6E F;  2UUI A;  2P61 A;  4JJF A;  2V26 A;  4BJ6 C;  5KYN A;  3A11 A;  1TQG A;  2A69 F;  3U2M A;  5KYW B;  1TWH A;  2NG1 A;  3C63 A;  3DI5 A;  2IOQ A;  4C3D A;  4XPY A;  2W4M A;  4Z9I A;  3GM1 A;  4A4A A;  1J8M F;  2UUH A;  1TFK B;  1FMV A;  4EBK A;  4PJJ A;  1Q0F A;  4AL1 A;  2GA0 A;  3MX3 A;  3TJ6 A;  2BC5 A;  2OQM A;  2KW3 C;  4MTG A;  3TK0 A;  3U5S A;  2HJ3 A;  3S84 A;  3KYJ A;  2H7B A;  4ULW A;  5DQZ A;  5EGY A;  2CGE A;  4N06 A;  1QQ3 A;  3KH2 A;  3L8J A;  4HE8 D;  2ZPA A;  1TFO B;  1RKE B;  5KYX B;  4QI0 A;  4MVS A;  1IW7 F;  1K04 A;  1MNE A;  4JCH A;  1DOV A;  4OIP F;  1LPE A;  4L6R A;  3TJ5 A;  4DBR A;  4XEK A;  1MMG A;  5A6J A;  3W2V A;  2I8B A;  3RQF A;  4EBB A;  4OIR F;  2EIJ C;  5KYU B;  4JCZ A;  4MVZ A;  1NFN A;  3W2W A;  2NUP B;  4J30 B;  2W4B A;  4X0R A;  4C7O B;  2A6H F;  4N6C A;  3W8H A;  1C02 A;  2HSQ A;  1BR2 A;  1G4W R;  1ORY A;  1S05 A;  1ZHW A;  1WWP A;  3PCV A;  4B6I A;  3S0X A;  1ZU4 A;  4Q5S F;  2OOC A;  3F46 A;  2V3C C;  4KI2 A;  3M79 A;  4CIH A;  3J06 A;  2NUT A;  1HE1 A;  4NTB A;  3EPV A;  1BZ4 A;  3ZC4 A;  3H65 A;  1NLX A;  3B71 A;  1LIH A;  2R7S A;  3N2Z B;  4I3M A;  3QVZ A;  1EI7 A;  1K05 A;  4O6M A;  4DRH B;  1OR2 A;  2XM0 A;  3GOD A;  4LLC A;  2Y3G A;  4CDY A;  1Z63 A;  4ANJ A;  3NG1 A;  1QSP A;  2OEX A;  1A0B A;  3ABL C;  3GEE A;  3EZI A;  1A7D A;  4DBQ A;  1FAP B;  5DS5 A;  1ZW2 A;  2L81 A;  4XEV A;  1T6U A;  2Y39 A;  4JTD B;  4DRJ B;  2W45 A;  2R25 A;  4CS8 A;  2BE5 F;  2XS8 A;  3ZWI A;  4BEM J;  1ZU5 A;  2YKZ A;  1XZQ A;  1ZHY A;  2HZ8 A;  1FFT C;  3CAX A;  4MVQ A;  1ZW3 A;  3ZG1 A;  1EQ1 A;  2D4U A;  2X0C A;  2EIM C;  256B A;  4LAC B;  4YJW A;  4CJG A;  2MYS A;  1ORS C;  3AOU A;  1OCZ C;  5BQI A;  2HUJ A;  4XPW A;  1H9T A;  3K33 A;  5F5H A;  2L9J A;  2ZXR A;  3GM3 A;  4MS2 A;  5DS6 A;  1JPN A;  3A9C A;  1Z3I X;  4IAR A;  4JEB A;  3WAQ A;  2DYR C;  1CGN A;  1OKK D;  2QNL A;  3U2L A;  1NG1 A;  2R05 A;  3EQL F;  3ATP A;  2OJQ A;  3JZ0 A;  3LNM B;  4GEH A;  4W8K A;  4AE4 B;  4YK5 A;  4E0I A;  1HY5 A;  4GYT A;  3NDB B;  1XWJ A;  1XZP A;  2ICW G;  4NCQ A;  2WZG A;  4E7S A;  3OWT A;  4JEA A;  1VB5 A;  1FFH A;  3L8I A;  3MYF A;  4PJN A;  1HW1 A;  1D0Z A;  2PBE A;  2XM4 A;  1S7Z A;  4PR9 A;  2AWY A;  1LKX A;  2ZD9 A;  3TQO A;  4CIP A;  1J8Y F;  3E9V A;  4LER A;  2KQ9 A;  3IEE A;  4WGZ A;  4DVY P;  1AVO B;  4OD4 A;  4D4N A;  1MMA A;  2QE9 A;  5DVW A;  4ZLD A;  5HV9 A;  2J9B A;  3T6G B;  3ITF A;  4JE9 A;  3HTK C;  3C8Z A;  4N6H A;  2R7X A;  3T6B A;  1V55 C;  2IM8 A;  4RD9 A;  3HKK A;  1KU2 A;  2AVK A;  5E33 A;  4U9D A;  3S28 A;  2L7A A;  3KPH A;  4BG0 A;  4E7Z A;  2NUT B;  3C18 A;  1TKN A;  2R9R B;  2EPO A;  5COG A;  3SZR A;  1H7I A;  2KGO A;  2M4E A;  1MMD A;  1VOM A;  3IQ5 A;  2VAS A;  4GQH A;  2PX0 A;  1OQC A;  5GPG B;  2HS5 A;  4BJ5 C;  2CDQ A;  2A1D D;  1WN0 A;  4XQ1 A;  1YJG A;  3EGD A;  4DJ9 A;  2YZS A;  3C7J A;  3MFN A;  1NU7 D;  1ZVZ A;  3JCU Q;  3EHN A;  3NYJ A;  2IXM A;  5EK0 A;  3RKO F;  2YL7 A;  4PK4 A;  2PNO A;  2FGY A;  1LE2 A;  1JR8 A;  3BRJ A;  5F5F A;  3QVY A;  2CNW D;  2HSB A;  3GEI A;  1U89 A;  3EGX B;  4AX2 A;  2LP4 A;  1OW8 A;  3LLK A;  3S29 A;  2P6V A;  2ZXP A;  2R7O A;  3K66 A;  3KL4 A;  2Q9A A;  3EFO A;  1G5Z A;  3KKB A;  3R2P A;  3T4R A;  4Z9H A;  5A6B D;  5DLJ A;  1HMD A;  3NYM A;  3UGP A;  4XLN F;  2R7V A;  5JS5 A;  2Q4F A;  3DM9 B;  4XTK A;  1T01 A;  3AG1 C;  3EGD B;  1NZE A;  1N1C A;  5AGF A;  4AK9 A;  1YYJ A;  3V5Z A;  3SXM A;  4EBJ A;  1G4U S;  3SP1 A;  2C03 A;  2I15 A;  3W8I A;  2J7P D;  4G0H A;  1H9G A;  4IRU A;  5COM A;  2RD9 A;  3ASN C;  5KYW A;  3NMI A;  3UGO A;  2C04 A;  3G4X A;  2XL4 A;  2EIK C;  5CI8 A;  5T1D B;  1YA7 O;  4K7B A;  4NTF A;  3TOM A;  4EHP A;  3ZVR A;  3NMK A;  1QPU A;  1NFO A;  1VLS A;  2WVO A;  3EG9 B;  2JPU A;  5L3V A;  2QY9 A;  4NQF A;  2P0N A;  4OD5 A;  1LS1 A;  2YVK A;  4E0H A;  3FXH A;  1T9K A;  2L6F A;  3AG3 C;  3S9O A;  5A6K A;  2J7P A;  3VYW A;  2HMZ A;  1OCR C;  3DMD A; 
#chains in the Genus database with same CATH homology
 2FAP B;  4FAP B;  5GPG B;  4DRI B;  4DRH B;  2NPU A;  1FAP B;  3FAP B;  1AUE A;  1NSG B;  4DRJ B;  2RSE B;  2GAQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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