The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
124
|
sequence length |
374
|
structure length |
374
|
Chain Sequence |
MSKPHHATLESIKYTPGSLRLLDQRKLPLETVFDDVLTVEDIWSAIKEMRVRGAPAIAVSAALGIAVATQRKAANGELKSGREVQTFLLTSCDFVMTSRPTAVNLFNCLRDLKAQVDKLDPTKAAAEVAQAFVELAEAVYTNDVAFNEGIMRHGAAHILAAAKAEGRDKVSILTICNTGALATSRYGTALGVVRQLFYDGKLERVYACETRPWNQGARLTVYECVQEDIPCTLICDGAASSLMLNRKIDAVVVGADRICQNGDTANKIGTYNLAVSAKFHGVKLYVAAPTTTLDVKTASGNHVEIEEREPTEITTNLVTKQRVVADGPHLSIWNPVFDITPSELITGGIITEKGVQAPAASAPYYDIASIIAQA
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Crystal structure of the eukaryotic initiation factor 2B from Leishmania major at 2.1 A resolution
rcsb |
| molecule tags |
Translation
|
| source organism |
Leishmania major
|
| molecule keywords |
initiation factor 2B
|
| total genus |
124
|
| structure length |
374
|
| sequence length |
374
|
| chains with identical sequence |
B
|
| ec nomenclature |
ec
5.3.1.23: S-methyl-5-thioribose-1-phosphate isomerase. |
| pdb deposition date | 2005-06-17 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01008 | IF-2B | Initiation factor 2 subunit family |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Up-down Bundle | Four Helix Bundle (Hemerythrin (Met), subunit A) | translation initiation factor eif-2b, domain 1 | ||
| Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Translation initiation factor eif-2b; domain 2 |
