2FAPB

The structure of the immunophilin-immunosuppressant fkbp12-(c16)-ethoxy rapamycin complex interacting with huma
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
94
structure length
94
Chain Sequence
VAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRIS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution.
pubmed doi rcsb
molecule tags Complex (isomerase/kinase)
source organism Homo sapiens
molecule keywords FK506-BINDING PROTEIN
total genus 37
structure length 94
sequence length 94
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 1998-09-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.150 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) FKBP12-rapamycin binding domain 2fapB00
1FAPB 2GAQA 3FAPB 1AUEA 4DRJB 5GPGB 2FAPB 2NPUA 2RSEB 4DRIB 1NSGB 4FAPB 4DRHB
chains in the Genus database with same CATH superfamily
1E2XA 1MMGA 3L8IA 5E3AA 2NUPA 2ZD9A 3U2LA 2ZPAA 2XRHA 1LPEA 1OCCC 2GDCA 2P7VA 2R7XA 1TFKB 3DD7A 3DMDA 3ABLC 4Q7CA 5JP7A 3SXMA 1Y6DA 2H7BA 1CPRA 3T4RA 1D1BA 3C18A 1ZHZA 3A11A 5A6AA 5A6JA 3C8GD 4JW1A 1YAUO 2V3CC 4U9DA 2OJQA 5BQHA 3UGOA 3AQCA 1ZU5A 2KGOA 4Z9IA 3ZIBA 3GM1A 5A69A 1JAFA 5B3IA 3GM3A 3AJMA 1JMWA 4I1OB 2R7RA 3AG3C 3TD7A 2JD3A 2WZFA 3CSKA 1HW2A 1HMOA 2Y3BA 3RVZA 2Y69C 4IAQA 4R32A 1CGNA 3NYJA 4XEFA 4PJMA 1C02A 1QQ3A 4N6HA 3EH1A 5FZTA 1YLMA 1TQGA 3W4YA 1JRAA 4W8KA 1Q0KA 2UUIA 3UR3C 2WZLA 2R9RB 3V5YA 4BEJA 3TOLA 3TJ6A 2CDQA 3W2WA 1FAPB 1MNEA 4EUKB 3CEXA 1J8MF 4JVSA 4BJTA 3FOOA 2QUPA 3Q6NA 4N6CA 3GANA 1I5NA 4LDQA 2L9JA 3NKEA 1YDIA 3JT1A 2R05A 4HFKB 3O6XA 3K7DA 2P6VA 1SR2A 4QDLA 4C3DA 1M56C 2A1DD 3RYLA 1AEPA 1E85A 4AL0A 2V26A 1WGWA 3TQOA 5CIVA 4DRHB 1T9KA 4NCQA 3TJ5A 3RQGA 3ECSA 1OXBA 1RKCA 2NG1A 3I5QA 1WATA 4AK9A 2JPUA 4XQ1A 3WG7C 4MVQA 4EBBA 4NTBA 5AC5A 1FTSA 1GS9A 2A69F 4EKWA 5GPGB 5L0IA 2R7OA 1Z63A 1AVOB 4EIYA 2AVKA 1OR3A 4XPYA 4OD5A 3JRTA 2LFFA 5CI8A 3U2MA 3LNRA 3ZVRA 3L1MA 1JR8A 4DBRA 2BE5F 3K6BA 4FESA 5DS5A 3KYIA 1QPUA 5T3TA 1NLXA 2YL7A 3LEOA 3O55A 4XWJA 1G4WR 2OCCC 5F5FA 2Z15A 2R7VA 1W2WA 4N4WA 3KMIA 4E17A 4ZLDA 3LS1A 2BL2A 1CGME 1YVIA 3OWTA 3K33A 4PFOA 4CBEA 5AC4A 4O79A 2D5RB 1L7CA 2LP4A 4E0IA 2XLEA 4IWBA 5E2QA 1G5ZA 3EH2A 1T6QA 3QMKA 1TWAA 1CGOA 3MLGA 1RCPA 3ASOC 1DOWA 4ANJA 3FMSA 2Q00A 3I4UA 2ICWG 1UG7A 4JC7A 2G3VA 1M57C 2CCYA 2YL1A 1S05A 3ASNC 3EFOA 2J9UA 3EFOB 5B1BC 3LESA 1UFBA 1I4YA 1ZYRF 3DAFA 3FXHA 2IXNA 3Q7LA 3N0TA 2L7AA 1TR2A 3NYMA 2P61A 2YLDA 3GWLA 1BBHA 3IHUA 3K66A 2Q7RA 3S29A 4OINF 5DS4A 2OG2A 4K7BA 3C8ZA 5TJ5E 5EGYA 2H7OA 5L0HA 2XL4A 4YL3A 2OKUA 4KNVA 2J45A 3EGXB 3C8GB 1APCA 3EHMA 3NYLA 2HSQA 3C8GA 1GGQA 1TFOB 3EGXA 3ZDLA 3ZTZA 4WABA 2PP4A 3K1IC 1QZXA 1OKKD 3KH2A 2KNHA 3M4CA 1QSPA 4MVOA 5DVWA 3HNJA 4CS8A 2IOQA 3G4XA 3U3BA 4W8PA 3EHNA 4E7SA 2IYLD 2P1AA 3LEVA 2GA0A 3S90A 2VB6A 3JSZA 4ZLCA 1NU7D 3V7OA 1KU2A 2YLGA 4LLEA 4LERA 2J8WA 2L6HA 2ZXPA 3PMRA 3TULA 2TMVP 3FHDA 4P9FA 4CSAC 4NTFA 3ZTMA 1VMAA 3DI5A 3VM6A 2PNOA 3QVZA 4M63A 3S0XA 4JKVA 2KQ9A 4OIRF 3B9QA 4P6IC 4CJOA 1C17M 2UUHA 2WVNA 2Y39A 5KYWB 2R7SA 4JE9A 4JZAA 4DBQA 5KYWA 1RXQA 4JJFA 4MW8A 2FFHA 2D4UA 3O39A 2ASRA 2PX3A 3U3FA 2Y3HA 3EZIA 3ABMC 4JTCB 2GWWA 5A6BD 4YN0B 4JTAB 4IJJA 1FNTc 2G3KA 3DE8A 1YYXA 2VH3A 3FOPA 3H2VA 1TWGA 4H4KC 2XLDA 1Z7Qc 3HNLA 3M79A 2LFDA 4U5FE 4C3EA 3LNMB 2J46A 2YZSA 3U0CA 2YVKA 2LD6A 256BA 3ITFA 1NFNA 1QLEC 3PCVA 1ZHTA 4FWVA 3WAQA 1JPNA 5L3QA 3NMKA 3NRHA 3VAYA 3LAYA 3QW1A 4OD4A 2Q9BA 1G8XA 1LS1A 3C7JA 3DJUB 4C7OA 3NKDA 1D1CA 3JTLO 2Q3TA 4MTGA 4U9EA 3ZQYA 2Y3GA 4J32B 4PJLA 4KNWA 4BJ1A 5L0JA 3Q6MA 1LIHA 3RW0A 1T6IA 4JIOA 5HSWA 2QE9A 3LUTB 4K0DA 5E3CA 4BEMJ 5DS6A 4LACB 2XM4A 3W2VA 2VASA 2NPUA 2E87A 2H7VC 4KI2A 4WGZA 4BJ6A 4NTAA 4PFPA 1T6UA 1K05A 3S9OA 1A41A 3T6JA 1OCRC 5JUAA 1V4AA 2EPNA 4IARA 3U9MA 4AL1A 1V74B 5AGFA 4F4BA 1WOLA 3LLIA 1SF8A 3U5SA 3B0UX 2HV7A 5KYXB 1Z23A 4G0HA 3W8IA 2WL8A 3WHNA 5KYXA 4QI2A 4JEBA 2L6FA 1FFTC 4U5EE 4MTFA 4XEVA 4DVYP 1LVKA 4FX5A 3UMIA 2B0JA 1Q0GA 1T01A 1TWHA 4E0HA 1HMDA 2WVQA 3AG4C 4HFFB 1BR4A 1MMDA 2J9VA 5L0CA 1FFHA 1S7ZA 2OQMA 1XWJA 3NMIA 4BPMA 2AWYA 4ER9A 4I44A 4JEAA 2R7UA 4DVZA 2HS5A 4JCHA 2IBFA 4OIQF 1SYQA 4CS8C 4B6IA 4XLNF 2LCHA 3B29A 3NMJA 3HTKC 1OKKA 2XSEA 2YL3A 4MTOA 3B0VC 3C63A 4XLPF 1VYIA 1YJGA 2M4EA 4O6MA 4YL0A 1AUEA 1YARO 4CIHA 1A0BA 2EPLX 1EA8A 1VB5A 2F22A 1B68A 2NUTB 1YZCA 3DJNB 3I5PA 2NUTA 2DB4A 3KYJA 4X0RA 1ORYA 4JURI 2AU5A 3MBGA 2XXAB 4L6RA 3U8VA 2XXAA 3RVYA 3DM5A 4CJGA 4PJJA 3SZRA 2KC3A 4CIPA 3EG9B 3KPHA 1OQCA 2A68F 2QTVA 3EG9A 4CS9C 3EGDB 1WN0A 2R02A 3EGDA 1OW8A 1I4ZA 2RD9A 3GODA 2YKZA 3DKAA 1TWCA 2EPKX 2QY9A 1NBBA 3G50A 2C03A 2IXOA 3ABKC 3EPVA 1H7IA 3S27A 2KYHA 5A6BA 3QW0A 2VCBA 4QI0A 1Y4CA 2B0HA 3DE9A 4A4AA 3IQ5A 2BC5A 4JRZA 2CNWD 2DYRC 2R7TA 2HSBA 1OCOC 5HV9A 3HNKA 2DYSC 2HV6A 1C03A 1MNDA 2A0BA 1R4TA 2EPOA 4J7TA 1CPQA 1ORJA 4LLCA 5COFA 3T6GB 3V5ZA 3MYFA 3L0IA 5KYUA 4Q4ZF 3RKOF 3RQFA 3DXJF 3SP1A 1NZEA 1ZU4A 1MMAA 2C04A 2VCAA 2XLWA 3JYHA 1DOVA 2ZXWC 4KC9A 2J7PD 3LLKA 2A6EF 3J06A 2L81A 1ZVZA 2XM0A 4H54A 4J7YA 3RIPA 3ZQVA 2DI3A 3GEEA 1ZW3A 1Z3IX 4IAOA 4MVMA 1LM3B 2LK4A 4PK4A 2MWQA 3QVYA 1PV3A 2YHSA 3T6BA 4IGGA 1BZ4A 3AG2C 1EQ1A 3EJNA 5KYYB 4BJ6C 3OA1A 1L3PA 5KYYA 3JRMO 4I1MA 2XS1A 2GFHA 2Q9CA 3QZCA 3IEEA 4HE8D 4EHPA 1ZW2A 4MVSA 5JT4A 2XS8A 3US6A 3EZHA 3Q7GA 1WWPA 3GWNA 1N1CA 4NY3A 1FR0A 1XZPA 3B71A 3DWWA 3JCUQ 4MVZA 2HZ8A 1IZMA 1LE2A 5F28E 4WJ0A 1M2OA 3UMHA 2XLMA 5EK0A 4CX9A 4HEAJ 3BRJA 5COGA 4DJ9A 1LI5A 4CDYA 1G4US 3UNGC 2YWAA 2Q9AA 1U6HA 5L0GA 5KYNA 2Y3DA 2W9YA 1EI7A 2YEVA 3FAPB 1RKEB 3LS0A 1OW6A 1RKEA 2QLAA 5EHHA 1PCXA 4UDVA 2W4BA 4RBNA 2ZXOA 1HW1A 4BJ5A 2LIGA 3PDMP 1HE9A 4NC3A 5B3SC 3S28A 3CZ6A 3RH3A 3JSEO 3AGTA 2YLIA 4MS2A 1OR2A 1NFOA 4G7OF 4C7OB 1H9TA 1KTMA 1E84A 2FGYA 3IQTA 3UGPA 3LJBA 1PD0A 2OOCA 4Z9JA 3RFYA 3AG1C 3AQBA 4O7GA 4CDVA 1MMNA 2O9XA 5CI9A 4DRIB 4YT4A 1NG1A 4MVRA 1YA7O 3IQ6A 3PHF2 2YRFA 3HJCA 5COMA 3SXYA 2VC9A 4U5HA 1V54C 1BR2A 2KK1A 4EBKA 1EKYA 1ZZPA 2XLVA 3TK0A 3SEOA 2A0UA 2IXPA 2GAQA 1LS4A 2X0CA 4OIPF 1A7EA 2P0NA 1F1MA 4G78A 2J9BA 2ETSA 5D92A 1KNYA 1ZHYA 4E7ZA 5JS5A 4DOZA 5JVEA 1GQAA 1PD1A 1OCZC 3FDQA 1SZIA 5K0IA 2NSGA 3M1CB 3K1IA 1H6GA 3KKBA 4K1OA 3MYIA 2JX0A 3EQLF 4ONSA 4BJ5C 1O87A 2PFDA 2CYDA 5D91A 5E33A 5IY5C 2J9WA 3CQZA 4U5GA 1Z5ZA 3G4ZA 3V5XA 2CNWA 2XLOA 4YT2A 5DLJA 1OXKA 4BG0A 1VOMA 1MQVA 1WASA 4MQ9F 5BQGA 1WTYA 4P9TA 1K04A 3BEHA 5B1AC 3ZC4A 1FMVA 4A2NB 2R7QA 5L3VA 4CSAA 2AP3A 4U5CE 3VRCA 2J0WA 3VF0A 4PR9A 2J0XA 2X51A 3H65A 2XLHA 2L6GA 2J7PA 3U8PA 2QNLA 3ZG1A 4IRUA 3SNHA 3NDBB 2XL6A 3B0PA 3IQCA 1VK5A 1ZHXA 2A6HF 3NG1A 4WGYA 3WODF 4DXWA 3L34A 5A6KA 2LQGA 3HKKA 2HKVA 2IM8A 1M6TA 2PBEA 2W45A 3KL4A 3UMKA 1Q0DA 3IPMO 2EINC 2OU6A 2YQYA 1ORSC 3GEHA 4LDKA 2YL0A 4C3BA 4MNDA 4RD9A 1GM5A 3K1HA 4DRJB 2AWCA 4YWQA 3R7CA 3SYNA 3AGUA 3DZAA 4GEHA 2MYSA 3QTHA 4AE4B 1IW7F 2OJED 1QVXA 2Q4FA 4AE4A 2XL8A 4G7HF 1K40A 2KSFA 5DQTA 3GM2A 1D0YA 3FAJA 3E70C 3N2ZB 1U89A 1A7VA 2KW3C 2KJGA 2WZGA 4O6YA 4J30B 4JCZA 1JOGA 1J8YF 2H8AA 4PACA 3U9JA 4AX2A 2WB7A 2I15A 4D4NA 1VLSA 3SXKA 3A9CA 1H9GA 1A7DA 1M2VB 1TKNA 2WVOA 5KYUB 1M2VA 1BR1A 3N24A 2PF4E 3L8JA 1Z6AA 3JZ0A 2W4MA 1VYKA 3R2PA 3JYYA 4JTDB 5T3WA 5BQIA 4OIOF 4Q5SF 2DGJA 3RQEA 2R25A 1D0ZA 4XEKA 1D0XA 1NU9C 2G62A 5JLIA 2EIKC 1LE4A 3F47A 3O10A 4GQHA 3C62A 4ULWA 4YL1A 4G7ZF 3T9OA 1ZHWA 4O6NA 5L0DA 2MHRA 3W8HA 4N06A 3CAXA 2OEVA 3MFNA 1T5OA 1YZAA 3MX3A 4XPWA 4YT5A 4RDAA 3X2QC 2CW0F 2R7WA 2HJ3A 4KBLA 2ZXRA 3DM9B 4MW3A 4MVUA 4XPXA 4YT8A 1LI7A 1HE1A 2OEXA 2HUJA 1LKXA 2EIMC 2M64A 1RMVA 2HJMA 1Q0MA 3SXZA 4FAPB 1OW7A 1XZQA 3RF3A 4ULVA 3F46A 3HNIA 1FMWA 3AOUA 1E83A 2LSEA 4U5DE 4JJGA 4PJNA 4YK5A 4CS7A 3DAGA 1ST6A 4CDAA 2VCCA 3POVA 4GYTA 3S84A 1D1AA 2EIJC 4LDRA 1E86A 3ATPA 4Z9HA 2FAPB 1YYJA 2HMQA 2I8BA 2R03A 3GEIA 1R5ID 3OEOA 1V55C 3M4BA 1BDJB 2HFIA 5T1DB 1Q0FA 3HLZA 4EWCA 3ZWIA 5BUOA 3X1OA 2RSEB 5F5HA 2NSFA 1VLTA 3GORA 1JPJA 2IXMA 3ZSUA 4D4XA 1RJ9B 1O5HA 4IB4A 5DQZA 1RJ9A 1YA9A 3E9VA 5JRAA 2CGEA 2HMZA 4I3MA 5L0FA 1QKRA 1NSGB 4XTKA 4E18A 2EPMX 3FVYA 5FCLA 2EILC 3H2UA 4EBJA 1VTMP 3VYWA 1U0BB 1SMYF 1O3UA 3M15A 4NQFA 4U5BE 4CS9A 1HY5A 2PX0A 3TOMA 5JSLA 4YJWA 2NUPB
chains in the Genus database with same CATH topology
1FAPB 2GAQA 3FAPB 1AUEA 4DRJB 5GPGB 2FAPB 2NPUA 2RSEB 4DRIB 1NSGB 4FAPB 4DRHB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FAP B;  2GAQ A;  3FAP B;  1AUE A;  4DRJ B;  5GPG B;  2FAP B;  2NPU A;  2RSE B;  4DRI B;  1NSG B;  4FAP B;  4DRH B; 
#chains in the Genus database with same CATH topology
 1E2X A;  1MMG A;  3L8I A;  5E3A A;  2NUP A;  2ZD9 A;  3U2L A;  2ZPA A;  2XRH A;  1LPE A;  1OCC C;  2GDC A;  2P7V A;  2R7X A;  1TFK B;  3DD7 A;  3DMD A;  3ABL C;  4Q7C A;  5JP7 A;  3SXM A;  1Y6D A;  2H7B A;  1CPR A;  3T4R A;  1D1B A;  3C18 A;  1ZHZ A;  3A11 A;  5A6A A;  5A6J A;  3C8G D;  4JW1 A;  1YAU O;  2V3C C;  4U9D A;  2OJQ A;  5BQH A;  3UGO A;  3AQC A;  1ZU5 A;  2KGO A;  4Z9I A;  3ZIB A;  3GM1 A;  5A69 A;  1JAF A;  5B3I A;  3GM3 A;  3AJM A;  1JMW A;  4I1O B;  2R7R A;  3AG3 C;  3TD7 A;  2JD3 A;  2WZF A;  3CSK A;  1HW2 A;  1HMO A;  2Y3B A;  3RVZ A;  2Y69 C;  4IAQ A;  4R32 A;  1CGN A;  3NYJ A;  4XEF A;  4PJM A;  1C02 A;  1QQ3 A;  4N6H A;  3EH1 A;  5FZT A;  1YLM A;  1TQG A;  3W4Y A;  1JRA A;  4W8K A;  1Q0K A;  2UUI A;  3UR3 C;  2WZL A;  2R9R B;  3V5Y A;  4BEJ A;  3TOL A;  3TJ6 A;  2CDQ A;  3W2W A;  1FAP B;  1MNE A;  4EUK B;  3CEX A;  1J8M F;  4JVS A;  4BJT A;  3FOO A;  2QUP A;  3Q6N A;  4N6C A;  3GAN A;  1I5N A;  4LDQ A;  2L9J A;  3NKE A;  1YDI A;  3JT1 A;  2R05 A;  4HFK B;  3O6X A;  3K7D A;  2P6V A;  1SR2 A;  4QDL A;  4C3D A;  1M56 C;  2A1D D;  3RYL A;  1AEP A;  1E85 A;  4AL0 A;  2V26 A;  1WGW A;  3TQO A;  5CIV A;  4DRH B;  1T9K A;  4NCQ A;  3TJ5 A;  3RQG A;  3ECS A;  1OXB A;  1RKC A;  2NG1 A;  3I5Q A;  1WAT A;  4AK9 A;  2JPU A;  4XQ1 A;  3WG7 C;  4MVQ A;  4EBB A;  4NTB A;  5AC5 A;  1FTS A;  1GS9 A;  2A69 F;  4EKW A;  5GPG B;  5L0I A;  2R7O A;  1Z63 A;  1AVO B;  4EIY A;  2AVK A;  1OR3 A;  4XPY A;  4OD5 A;  3JRT A;  2LFF A;  5CI8 A;  3U2M A;  3LNR A;  3ZVR A;  3L1M A;  1JR8 A;  4DBR A;  2BE5 F;  3K6B A;  4FES A;  5DS5 A;  3KYI A;  1QPU A;  5T3T A;  1NLX A;  2YL7 A;  3LEO A;  3O55 A;  4XWJ A;  1G4W R;  2OCC C;  5F5F A;  2Z15 A;  2R7V A;  1W2W A;  4N4W A;  3KMI A;  4E17 A;  4ZLD A;  3LS1 A;  2BL2 A;  1CGM E;  1YVI A;  3OWT A;  3K33 A;  4PFO A;  4CBE A;  5AC4 A;  4O79 A;  2D5R B;  1L7C A;  2LP4 A;  4E0I A;  2XLE A;  4IWB A;  5E2Q A;  1G5Z A;  3EH2 A;  1T6Q A;  3QMK A;  1TWA A;  1CGO A;  3MLG A;  1RCP A;  3ASO C;  1DOW A;  4ANJ A;  3FMS A;  2Q00 A;  3I4U A;  2ICW G;  1UG7 A;  4JC7 A;  2G3V A;  1M57 C;  2CCY A;  2YL1 A;  1S05 A;  3ASN C;  3EFO A;  2J9U A;  3EFO B;  5B1B C;  3LES A;  1UFB A;  1I4Y A;  1ZYR F;  3DAF A;  3FXH A;  2IXN A;  3Q7L A;  3N0T A;  2L7A A;  1TR2 A;  3NYM A;  2P61 A;  2YLD A;  3GWL A;  1BBH A;  3IHU A;  3K66 A;  2Q7R A;  3S29 A;  4OIN F;  5DS4 A;  2OG2 A;  4K7B A;  3C8Z A;  5TJ5 E;  5EGY A;  2H7O A;  5L0H A;  2XL4 A;  4YL3 A;  2OKU A;  4KNV A;  2J45 A;  3EGX B;  3C8G B;  1APC A;  3EHM A;  3NYL A;  2HSQ A;  3C8G A;  1GGQ A;  1TFO B;  3EGX A;  3ZDL A;  3ZTZ A;  4WAB A;  2PP4 A;  3K1I C;  1QZX A;  1OKK D;  3KH2 A;  2KNH A;  3M4C A;  1QSP A;  4MVO A;  5DVW A;  3HNJ A;  4CS8 A;  2IOQ A;  3G4X A;  3U3B A;  4W8P A;  3EHN A;  4E7S A;  2IYL D;  2P1A A;  3LEV A;  2GA0 A;  3S90 A;  2VB6 A;  3JSZ A;  4ZLC A;  1NU7 D;  3V7O A;  1KU2 A;  2YLG A;  4LLE A;  4LER A;  2J8W A;  2L6H A;  2ZXP A;  3PMR A;  3TUL A;  2TMV P;  3FHD A;  4P9F A;  4CSA C;  4NTF A;  3ZTM A;  1VMA A;  3DI5 A;  3VM6 A;  2PNO A;  3QVZ A;  4M63 A;  3S0X A;  4JKV A;  2KQ9 A;  4OIR F;  3B9Q A;  4P6I C;  4CJO A;  1C17 M;  2UUH A;  2WVN A;  2Y39 A;  5KYW B;  2R7S A;  4JE9 A;  4JZA A;  4DBQ A;  5KYW A;  1RXQ A;  4JJF A;  4MW8 A;  2FFH A;  2D4U A;  3O39 A;  2ASR A;  2PX3 A;  3U3F A;  2Y3H A;  3EZI A;  3ABM C;  4JTC B;  2GWW A;  5A6B D;  4YN0 B;  4JTA B;  4IJJ A;  1FNT c;  2G3K A;  3DE8 A;  1YYX A;  2VH3 A;  3FOP A;  3H2V A;  1TWG A;  4H4K C;  2XLD A;  1Z7Q c;  3HNL A;  3M79 A;  2LFD A;  4U5F E;  4C3E A;  3LNM B;  2J46 A;  2YZS A;  3U0C A;  2YVK A;  2LD6 A;  256B A;  3ITF A;  1NFN A;  1QLE C;  3PCV A;  1ZHT A;  4FWV A;  3WAQ A;  1JPN A;  5L3Q A;  3NMK A;  3NRH A;  3VAY A;  3LAY A;  3QW1 A;  4OD4 A;  2Q9B A;  1G8X A;  1LS1 A;  3C7J A;  3DJU B;  4C7O A;  3NKD A;  1D1C A;  3JTL O;  2Q3T A;  4MTG A;  4U9E A;  3ZQY A;  2Y3G A;  4J32 B;  4PJL A;  4KNW A;  4BJ1 A;  5L0J A;  3Q6M A;  1LIH A;  3RW0 A;  1T6I A;  4JIO A;  5HSW A;  2QE9 A;  3LUT B;  4K0D A;  5E3C A;  4BEM J;  5DS6 A;  4LAC B;  2XM4 A;  3W2V A;  2VAS A;  2NPU A;  2E87 A;  2H7V C;  4KI2 A;  4WGZ A;  4BJ6 A;  4NTA A;  4PFP A;  1T6U A;  1K05 A;  3S9O A;  1A41 A;  3T6J A;  1OCR C;  5JUA A;  1V4A A;  2EPN A;  4IAR A;  3U9M A;  4AL1 A;  1V74 B;  5AGF A;  4F4B A;  1WOL A;  3LLI A;  1SF8 A;  3U5S A;  3B0U X;  2HV7 A;  5KYX B;  1Z23 A;  4G0H A;  3W8I A;  2WL8 A;  3WHN A;  5KYX A;  4QI2 A;  4JEB A;  2L6F A;  1FFT C;  4U5E E;  4MTF A;  4XEV A;  4DVY P;  1LVK A;  4FX5 A;  3UMI A;  2B0J A;  1Q0G A;  1T01 A;  1TWH A;  4E0H A;  1HMD A;  2WVQ A;  3AG4 C;  4HFF B;  1BR4 A;  1MMD A;  2J9V A;  5L0C A;  1FFH A;  1S7Z A;  2OQM A;  1XWJ A;  3NMI A;  4BPM A;  2AWY A;  4ER9 A;  4I44 A;  4JEA A;  2R7U A;  4DVZ A;  2HS5 A;  4JCH A;  2IBF A;  4OIQ F;  1SYQ A;  4CS8 C;  4B6I A;  4XLN F;  2LCH A;  3B29 A;  3NMJ A;  3HTK C;  1OKK A;  2XSE A;  2YL3 A;  4MTO A;  3B0V C;  3C63 A;  4XLP F;  1VYI A;  1YJG A;  2M4E A;  4O6M A;  4YL0 A;  1AUE A;  1YAR O;  4CIH A;  1A0B A;  2EPL X;  1EA8 A;  1VB5 A;  2F22 A;  1B68 A;  2NUT B;  1YZC A;  3DJN B;  3I5P A;  2NUT A;  2DB4 A;  3KYJ A;  4X0R A;  1ORY A;  4JUR I;  2AU5 A;  3MBG A;  2XXA B;  4L6R A;  3U8V A;  2XXA A;  3RVY A;  3DM5 A;  4CJG A;  4PJJ A;  3SZR A;  2KC3 A;  4CIP A;  3EG9 B;  3KPH A;  1OQC A;  2A68 F;  2QTV A;  3EG9 A;  4CS9 C;  3EGD B;  1WN0 A;  2R02 A;  3EGD A;  1OW8 A;  1I4Z A;  2RD9 A;  3GOD A;  2YKZ A;  3DKA A;  1TWC A;  2EPK X;  2QY9 A;  1NBB A;  3G50 A;  2C03 A;  2IXO A;  3ABK C;  3EPV A;  1H7I A;  3S27 A;  2KYH A;  5A6B A;  3QW0 A;  2VCB A;  4QI0 A;  1Y4C A;  2B0H A;  3DE9 A;  4A4A A;  3IQ5 A;  2BC5 A;  4JRZ A;  2CNW D;  2DYR C;  2R7T A;  2HSB A;  1OCO C;  5HV9 A;  3HNK A;  2DYS C;  2HV6 A;  1C03 A;  1MND A;  2A0B A;  1R4T A;  2EPO A;  4J7T A;  1CPQ A;  1ORJ A;  4LLC A;  5COF A;  3T6G B;  3V5Z A;  3MYF A;  3L0I A;  5KYU A;  4Q4Z F;  3RKO F;  3RQF A;  3DXJ F;  3SP1 A;  1NZE A;  1ZU4 A;  1MMA A;  2C04 A;  2VCA A;  2XLW A;  3JYH A;  1DOV A;  2ZXW C;  4KC9 A;  2J7P D;  3LLK A;  2A6E F;  3J06 A;  2L81 A;  1ZVZ A;  2XM0 A;  4H54 A;  4J7Y A;  3RIP A;  3ZQV A;  2DI3 A;  3GEE A;  1ZW3 A;  1Z3I X;  4IAO A;  4MVM A;  1LM3 B;  2LK4 A;  4PK4 A;  2MWQ A;  3QVY A;  1PV3 A;  2YHS A;  3T6B A;  4IGG A;  1BZ4 A;  3AG2 C;  1EQ1 A;  3EJN A;  5KYY B;  4BJ6 C;  3OA1 A;  1L3P A;  5KYY A;  3JRM O;  4I1M A;  2XS1 A;  2GFH A;  2Q9C A;  3QZC A;  3IEE A;  4HE8 D;  4EHP A;  1ZW2 A;  4MVS A;  5JT4 A;  2XS8 A;  3US6 A;  3EZH A;  3Q7G A;  1WWP A;  3GWN A;  1N1C A;  4NY3 A;  1FR0 A;  1XZP A;  3B71 A;  3DWW A;  3JCU Q;  4MVZ A;  2HZ8 A;  1IZM A;  1LE2 A;  5F28 E;  4WJ0 A;  1M2O A;  3UMH A;  2XLM A;  5EK0 A;  4CX9 A;  4HEA J;  3BRJ A;  5COG A;  4DJ9 A;  1LI5 A;  4CDY A;  1G4U S;  3UNG C;  2YWA A;  2Q9A A;  1U6H A;  5L0G A;  5KYN A;  2Y3D A;  2W9Y A;  1EI7 A;  2YEV A;  3FAP B;  1RKE B;  3LS0 A;  1OW6 A;  1RKE A;  2QLA A;  5EHH A;  1PCX A;  4UDV A;  2W4B A;  4RBN A;  2ZXO A;  1HW1 A;  4BJ5 A;  2LIG A;  3PDM P;  1HE9 A;  4NC3 A;  5B3S C;  3S28 A;  3CZ6 A;  3RH3 A;  3JSE O;  3AGT A;  2YLI A;  4MS2 A;  1OR2 A;  1NFO A;  4G7O F;  4C7O B;  1H9T A;  1KTM A;  1E84 A;  2FGY A;  3IQT A;  3UGP A;  3LJB A;  1PD0 A;  2OOC A;  4Z9J A;  3RFY A;  3AG1 C;  3AQB A;  4O7G A;  4CDV A;  1MMN A;  2O9X A;  5CI9 A;  4DRI B;  4YT4 A;  1NG1 A;  4MVR A;  1YA7 O;  3IQ6 A;  3PHF 2;  2YRF A;  3HJC A;  5COM A;  3SXY A;  2VC9 A;  4U5H A;  1V54 C;  1BR2 A;  2KK1 A;  4EBK A;  1EKY A;  1ZZP A;  2XLV A;  3TK0 A;  3SEO A;  2A0U A;  2IXP A;  2GAQ A;  1LS4 A;  2X0C A;  4OIP F;  1A7E A;  2P0N A;  1F1M A;  4G78 A;  2J9B A;  2ETS A;  5D92 A;  1KNY A;  1ZHY A;  4E7Z A;  5JS5 A;  4DOZ A;  5JVE A;  1GQA A;  1PD1 A;  1OCZ C;  3FDQ A;  1SZI A;  5K0I A;  2NSG A;  3M1C B;  3K1I A;  1H6G A;  3KKB A;  4K1O A;  3MYI A;  2JX0 A;  3EQL F;  4ONS A;  4BJ5 C;  1O87 A;  2PFD A;  2CYD A;  5D91 A;  5E33 A;  5IY5 C;  2J9W A;  3CQZ A;  4U5G A;  1Z5Z A;  3G4Z A;  3V5X A;  2CNW A;  2XLO A;  4YT2 A;  5DLJ A;  1OXK A;  4BG0 A;  1VOM A;  1MQV A;  1WAS A;  4MQ9 F;  5BQG A;  1WTY A;  4P9T A;  1K04 A;  3BEH A;  5B1A C;  3ZC4 A;  1FMV A;  4A2N B;  2R7Q A;  5L3V A;  4CSA A;  2AP3 A;  4U5C E;  3VRC A;  2J0W A;  3VF0 A;  4PR9 A;  2J0X A;  2X51 A;  3H65 A;  2XLH A;  2L6G A;  2J7P A;  3U8P A;  2QNL A;  3ZG1 A;  4IRU A;  3SNH A;  3NDB B;  2XL6 A;  3B0P A;  3IQC A;  1VK5 A;  1ZHX A;  2A6H F;  3NG1 A;  4WGY A;  3WOD F;  4DXW A;  3L34 A;  5A6K A;  2LQG A;  3HKK A;  2HKV A;  2IM8 A;  1M6T A;  2PBE A;  2W45 A;  3KL4 A;  3UMK A;  1Q0D A;  3IPM O;  2EIN C;  2OU6 A;  2YQY A;  1ORS C;  3GEH A;  4LDK A;  2YL0 A;  4C3B A;  4MND A;  4RD9 A;  1GM5 A;  3K1H A;  4DRJ B;  2AWC A;  4YWQ A;  3R7C A;  3SYN A;  3AGU A;  3DZA A;  4GEH A;  2MYS A;  3QTH A;  4AE4 B;  1IW7 F;  2OJE D;  1QVX A;  2Q4F A;  4AE4 A;  2XL8 A;  4G7H F;  1K40 A;  2KSF A;  5DQT A;  3GM2 A;  1D0Y A;  3FAJ A;  3E70 C;  3N2Z B;  1U89 A;  1A7V A;  2KW3 C;  2KJG A;  2WZG A;  4O6Y A;  4J30 B;  4JCZ A;  1JOG A;  1J8Y F;  2H8A A;  4PAC A;  3U9J A;  4AX2 A;  2WB7 A;  2I15 A;  4D4N A;  1VLS A;  3SXK A;  3A9C A;  1H9G A;  1A7D A;  1M2V B;  1TKN A;  2WVO A;  5KYU B;  1M2V A;  1BR1 A;  3N24 A;  2PF4 E;  3L8J A;  1Z6A A;  3JZ0 A;  2W4M A;  1VYK A;  3R2P A;  3JYY A;  4JTD B;  5T3W A;  5BQI A;  4OIO F;  4Q5S F;  2DGJ A;  3RQE A;  2R25 A;  1D0Z A;  4XEK A;  1D0X A;  1NU9 C;  2G62 A;  5JLI A;  2EIK C;  1LE4 A;  3F47 A;  3O10 A;  4GQH A;  3C62 A;  4ULW A;  4YL1 A;  4G7Z F;  3T9O A;  1ZHW A;  4O6N A;  5L0D A;  2MHR A;  3W8H A;  4N06 A;  3CAX A;  2OEV A;  3MFN A;  1T5O A;  1YZA A;  3MX3 A;  4XPW A;  4YT5 A;  4RDA A;  3X2Q C;  2CW0 F;  2R7W A;  2HJ3 A;  4KBL A;  2ZXR A;  3DM9 B;  4MW3 A;  4MVU A;  4XPX A;  4YT8 A;  1LI7 A;  1HE1 A;  2OEX A;  2HUJ A;  1LKX A;  2EIM C;  2M64 A;  1RMV A;  2HJM A;  1Q0M A;  3SXZ A;  4FAP B;  1OW7 A;  1XZQ A;  3RF3 A;  4ULV A;  3F46 A;  3HNI A;  1FMW A;  3AOU A;  1E83 A;  2LSE A;  4U5D E;  4JJG A;  4PJN A;  4YK5 A;  4CS7 A;  3DAG A;  1ST6 A;  4CDA A;  2VCC A;  3POV A;  4GYT A;  3S84 A;  1D1A A;  2EIJ C;  4LDR A;  1E86 A;  3ATP A;  4Z9H A;  2FAP B;  1YYJ A;  2HMQ A;  2I8B A;  2R03 A;  3GEI A;  1R5I D;  3OEO A;  1V55 C;  3M4B A;  1BDJ B;  2HFI A;  5T1D B;  1Q0F A;  3HLZ A;  4EWC A;  3ZWI A;  5BUO A;  3X1O A;  2RSE B;  5F5H A;  2NSF A;  1VLT A;  3GOR A;  1JPJ A;  2IXM A;  3ZSU A;  4D4X A;  1RJ9 B;  1O5H A;  4IB4 A;  5DQZ A;  1RJ9 A;  1YA9 A;  3E9V A;  5JRA A;  2CGE A;  2HMZ A;  4I3M A;  5L0F A;  1QKR A;  1NSG B;  4XTK A;  4E18 A;  2EPM X;  3FVY A;  5FCL A;  2EIL C;  3H2U A;  4EBJ A;  1VTM P;  3VYW A;  1U0B B;  1SMY F;  1O3U A;  3M15 A;  4NQF A;  4U5B E;  4CS9 A;  1HY5 A;  2PX0 A;  3TOM A;  5JSL A;  4YJW A;  2NUP B; 
#chains in the Genus database with same CATH homology
 1FAP B;  2GAQ A;  3FAP B;  1AUE A;  4DRJ B;  5GPG B;  2FAP B;  2NPU A;  2RSE B;  4DRI B;  1NSG B;  4FAP B;  4DRH B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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