2Q8UA

Crystal structure of mre11 from thermotoga maritima msb8 (tm1635) at 2.20 a resolution
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
329
structure length
308
Chain Sequence
HHHHHVINLKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAREIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNFPGYVRVVYEEDSGILPDLMGEIDNLVKIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair.
pubmed doi rcsb
molecule tags Hydrolase
source organism Thermotoga maritima msb8
molecule keywords Exonuclease, putative
total genus 94
structure length 308
sequence length 329
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.160.210 Alpha Beta 2-Layer Sandwich Double Stranded RNA Binding Domain DNA double-strand break repair nuclease 2q8uA02
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2q8uA01
1S70A 1QHWA 3LL8A 1T71A 2IE4C 3T1IA 4I5NC 1HO5A 2WDDA 3E7BA 1NNWA 4H2IA 3K7VC 4ZVZA 2IE3C 4O5GA 4M0VA 5J28A 2BQ8X 1WARA 3EGGA 3H66A 3RL4A 1S3LA 3ZTVA 2GJUA 2QFPA 3RL5A 2O8AA 2JOGA 2NYMC 3E7AA 2BCDA 3P71C 5INBA 2Z1AA 3IB7A 2DFJA 3KBPA 2YVTA 4TUIA 1QFCA 1MF8A 1S3NA 5F3WA 3H63A 4H1SA 1USHA 4I5LC 1S95A 4KKZA 3H69A 1UF3A 2WDEA 3PSNA 3DSCA 3DSDA 1HP1A 3N5UA 2QFRA 1OIDA 4H1YP 2BDXA 2HY1A 4B2OA 1SU1A 5C1VA 3GVEA 4ZX2A 3DW8C 1XZWA 4FBQA 2IAEC 4YKEA 4ORBA 4O4KA 3FGAC 3QG5C 4FBWA 4OR9A 2NPPC 4JA9A 4KBPA 4MOYA 5GTUA 2WDCA 2ZBMA 5JJTA 4DHLA 2QJCA 1OIEA 4DSYA 1IT6A 3EGHA 3V4YA 3K7WC 1V73A 1S8EA 1HPUA 1FJMA 4HD0A 1WAO1 4LTYA 3RL3A 3HVQA 4UT3A 2A22A 2HYPA 4MP0A 5DNYA 2Q8UA 4V0WA 4UT2A 4WWLA 4XPNA 4H2BA 3H68A 2Z72A 4H2FA 2USHA 3C5WC 3QFNA 3JYFA 3H67A 4FBKA 3RQZA 4ORAA 2WDFA 4J6OA 3H60A 4TUGA 1TCOA 4UT3B 1Z2WA 2R17A 4O43A 5B8IA 3AUZA 3C9FA 3PSOA 4LACC 5HPEA 3THNA 1T70A 3QFMA 2Z06A 3ICFA 3AV0A 1S3MA 4G9JA 3CK2A 4LU9A 4ORCA 3TGHA 1JK7A 4UWQA 1G5BA 3H61A 4NZVA 4IL1A 3H62B 1M63A 3H64A 2AHDA 3IVEA 4H2GA 2O8GA 4V0XA 4DT2A 2NYLC 3QFKA 1XM7A 5JPEA 5EQVA 4MOVA 2KKNA 1UTEA 2P6BA 2NXFA 3ZU0A 2XMOA 1W24A 2HYOA 4O24A 4F0ZA 2CV9A 1OI8A 1U32A 5JPFA 1Z2XA 4V0VA 4IYPC 4FCXA 1II7A 1KBPA 4Q7FA 3IVDA 3QFOA 3IB8A 1AUIA 4JA7A 5IOHA 3THOB
chains in the Genus database with same CATH superfamily
4F6NA 1NEIA 3J81C 2JYAA 2EOSA 1BBGA 2LTRA 2JWOA 1ZAAC 2UXCE 2IHR1 4O5GA 3UK3C 5J28A 4DMIA 1YUIA 1IQSA 2EMXA 2EN3A 1YYKA 3ZTVA 4BHBA 1KJKA 2WBSA 1G2FC 2GJUA 5ADZA 2KHXA 2LBSB 1T4LB 2JOGA 4MLQA 5INBA 3IB7A 3KBPA 2JR1A 2L3JA 4M30A 2V87A 3HPZA 5F3WA 4H1SA 2LJHA 2DGCA 1G2DC 1HNWE 2LUQA 2VQFE 2MDGA 4DV5E 3DSCA 3DSDA 2NUGA 3JU0A 1OIDA 2LRSA 2BDXA 4F9BB 2ZO9B 2D9HA 2YTJA 2EMGA 4GKKE 2RPCA 2EQ3A 4JI3E 4YKEA 1X49A 1MEYC 2EPRA 4WSGA 2EOIA 3QG5C 2DB2A 4JA9A 4MOYA 1O0WA 3C4TA 2QJCA 2EN6A 2ELYA 2EP3A 5AC5A 3V4YA 1IMUA 3K7WC 1HPUA 2CSHA 4WXCA 5DNYA 2N8XA 3EPHA 2A25A 5AE2A 2JPAA 2LV2A 1A1FA 4JI7E 1A1HA 4XPNA 5FLXC 2EMBA 4H2FA 2EM5A 3C5WC 3H67A 4NXME 3IWCA 2HC5A 1WXRA 1X6HA 2RS6A 4DUYE 3C9FA 5HPEA 4F9AB 3IWBA 3OMLA 4JI8E 3EPKA 2Z06A 2ODRC 2EMWA 2EPXA 2EE8A 4JI2E 1QU6A 3E0JA 3MHSC 3LMLA 4LU9A 3LLHA 3MHHC 1ZR9A 2GPIA 4UWQA 2L2KB 2L6MA 4NZVA 1PKPA 2KOUA 1M63A 4R2DA 2I13A 1KYQA 2HGHA 2EMIA 2EOEA 2EPCA 4DT2A 1LLMC 4GKJE 1XM7A 5EQVA 1AH5A 1UTEA 2E5LE 1FJGE 3P1XA 2UUBE 1UN6B 4R8OA 2EM9A 2EM7A 4NXNE 3BIDA 2YRKA 5LL6R 4V0VA 2LTSA 4ZYGA 1IBME 4B3RE 2FGGA 3TQMA 2V83A 4L5NC 4M2ZA 4DV2E 2EPOA 1RQ0A 2LMZA 2LE2A 2EM4A 1T71A 4I5NC 2EN2A 3EQ1A 2YTNA 1PJSA 3K7VC 4F6MA 2YSPA 4M0VA 4DR5E 4BS9A 2BQ8X 3H66A 3EGGA 2YSOA 1S3LA 2EPMX 3T1HE 3RL5A 2R76A 5KL4A 4F9CB 4Q35B 3E7AA 1YFHA 1YUJA 4IJDA 2EOYA 2RQLA 3H09A 2UXDE 2YVTA 2N3GA 4LF4E 4BC7A 2M4IA 1TF3A 2LVHA 4L8NA 2DIXA 4AQYE 1IBLE 5A6BA 1J26A 2WCC3 3PSNA 4LF8E 1TF6A 2J7JA 2L2MA 4F2JC 5AE1A 2MC6A 2HY1A 4B2OA 2E72A 1SU1A 4JI0E 1EH6A 2VF1A 3C6MA 1XZWA 4HTGA 4O4KA 3VYYA 4FBWA 2EOOA 1EH8A 3VK6A 2EOXA 5JJTA 1NCSA 4R2EA 2LT7A 2EM6A 1F2IG 4JYAE 2ODRD 1N33E 2EMAA 1A1KA 2JY9A 3RL3A 2KONA 4LTYA 4UT3A 2A22A 2EPKX 2L8TA 2EMLA 5A6KA 5KL3A 4YY3E 1X48A 2WBTA 4MLVA 4R2PA 4KHPE 2EOZA 1Z1BA 3QFNA 3JYFA 5A6JA 4X9JA 4FBKA 4ORAA 4WX9A 4DR6E 2B9DA 5KL5A 2DMYA 4JI1E 4LFAE 1TCOA 1JK2A 2YEQA 1N34E 1Z2WA 4O43A 1BB8A 3PSOA 4P7DA 2RTXA 4LACC 4M9VC 1T70A 2ADRA 4DR4E 4OX9E 1DI2A 4F54A 3RMPA 3ICFA 1UHZA 2YTDA 1XNQE 2EORA 3JTZA 1WRJA 5AC4A 4LFCE 2EJ4A 2EM0A 3H62B 2L33A 3H64A 4FK5C 4DKKA 3EPJA 4DV4E 2EMYA 2B3TB 5A6BD 1UILA 2CT1A 2NXFA 5TSEA 2XMOA 1A1GA 5KL2A 4I8OA 2LO3A 2CV9A 2YTQA 4WPYA 5KL7A 4X62E 1U32A 1YSAC 4IYPC 4FCXA 2VE7C 1TN9A 1II7A 2V85A 3QFOA 1AUIA 2L92A 1T38A 1SFEA 2EPNA 3THOB 4BCAA 1P47A 4DV6E 5LMUE 1QHWA 4WSPA 4BHCA 1GZ6A 3T1IA 1RC7A 5A6AA 2UUAE 5AASA 1NNWA 1DQ3A 3BF2A 2IE3C 4ZVZA 2N3HA 4K0KE 4WFTA 2ZOAA 1WARA 3RL4A 4ZYEA 1GTKA 2O8AA 2PRTA 2EOMA 2EZ6A 3P71C 2ZM6E 4DR1E 2Z1AA 2M7QA 2VQEE 1QFCA 1MF8A 3OTOE 4B3SE 2GHFA 3H63A 2EL5A 1USHA 1A1LA 2YU5A 1WJPA 1YPNA 1S95A 3ADIA 1T4OA 1JK1A 2NUEA 2VRDA 4LF6E 2WDEA 2EPPA 2B7TA 1PDAA 2YTOA 2ENAA 1XMOE 1HP1A 3N5UA 4DV3E 2E1MA 2QFRA 4H1YP 2EMKA 2EMFA 4R2RA 3ADJA 3GVEA 2JOXA 4FBQA 2JOBA 1ZU1A 4RHBB 1BBOA 2CTDA 4OR9A 5GTUA 2DLKA 2WDCA 2ZBMA 2EOFA 4DHLA 5IV8B 4DSYA 1A1IA 2EQ1A 2DRPA 4R2QA 3ADLA 3KZYA 1UBDC 1V73A 1FJMA 4HD0A 2L2NA 3JAMC 3HPSA 4MP0A 2V8QB 4KWYA 2MC5A 2EL6A 5A69A 4UT2A 2ENCA 4WWLA 4H2BA 2YTGA 3DJWA 2Z72A 1X47A 2JVAA 1DGCA 4DV1E 3RQZA 2YWQA 2NA2A 3H60A 4TUGA 3J7Yp 2F4VE 2R17A 5B8IA 4BC9A 4P78A 3AUZA 2B7VA 4BMJA 2BBGA 1IBKE 3QFMA 2DXNA 1GQEA 1T4NA 2R1FA 1N32E 3CK2A 2EN7A 1G5BA 3H61A 4IL1A 5IT9C 2JXPA 2LUPB 4B3TE 4KZSA 4LFBE 2EQ0A 1SR9A 2AHDA 1MGTA 3IVEA 5LMNE 4H2GA 3HQ1A 3IWDA 2NYLC 3QFKA 5AE3A 5JPEA 4MOVA 4NHRA 2DMIA 3ZU0A 2HHHE 4GEQB 1W24A 2RSMA 2HYOA 4O24A 1N3GA 1J5EE 4F0ZA 2ELZA 5JPFA 2YTPA 3C4BA 4OOGC 4YHHE 2EMZA 1KBPA 2MKNA 2WZOA 2EMHA 2EOQA 1ZBQA 5IOHA 2YPNA 4V0WA 4DUZE 4DR3E 1S70A 1STUA 3LL8A 1B69A 2WBUA 2IE4C 2H36X 1HO5A 2WDDA 3E7BA 2EM8A 3C6KA 3VYXA 4H2IA 2NABA 3BGHA 2EOJA 2YTEA 3T1YE 1FKAE 2UXBE 4DV0E 4DR2E 1ZBTA 2EN8A 1AAYA 4JI4E 2QFPA 2F8BA 2YU8A 1RMDA 4R2SA 2YTIA 1I94E 1A1JA 2NYMC 2BCDA 5IXMB 2EWLA 5A2QC 4DR7E 2EN4A 2DFJA 4TUIA 3K6QA 5CFFE 3J80C 1S3NA 2EN1A 3L00A 5T6JA 1L4SA 4J8ZA 1T39A 1HR0E 4WYQB 4I5LC 4KKZA 3H69A 3ECRA 3VHTB 2FTXB 2EM3A 4B3ME 1UF3A 2MKDA 2DXLA 1X3CA 1HNZE 4HEIA 2GLIA 3FIGA 4JI5E 3F6HA 2CPNA 4R03A 1N36E 2UUCE 1X6FA 1WHNA 2ENHA 5C1VA 4ZX2A 4X65E 1WHQA 2G7HA 3DW8C 2DSYA 2IAEC 2EPAA 3HXLA 4LF9E 3D03A 3FGAC 4ORBA 3FLOA 3M99B 2EPUA 2NPPC 4KBPA 5LLQA 1PJTA 3ZOQB 1OIEA 1QNTA 1IT6A 3EGHA 2DLQA 3EPLA 1XMQE 4ZYHA 4IS1C 3KZZA 2EPLX 1S8EA 2YZTA 2EL4A 4X8WA 4Q28A 1WAO1 3HVQA 2HYPA 4DV7E 2EOHA 2V89A 1HNXE 2Q8UA 2M1SA 2LJUA 4GZNC 3H68A 1IQOA 2EPZA 4JV5E 4X66E 2USHA 2JP9A 2RS7A 2YRMA 1YYWA 2WDFA 4J6OA 2YTFA 3BBGA 3MSWA 2NUFA 2EM2A 2V86A 4UT3B 2BB8A 4X64E 4N4RB 1X5WA 2HJJA 3THNA 4ZYDA 3J7AG 3AV0A 2EMCA 2L3CA 1S3MA 3KWRA 4G9JA 4ORCA 2RSIA 3TGHA 2K4VA 1PJQA 4R2AA 1JK7A 1YZ9A 3DF6A 1YYOA 4WXDA 1EH7A 2M9AA 3HTXA 2K7IA 2YRHA 2UU9E 2I9IA 1X6EA 2LCEA 2O8GA 3ADGA 5BR8E 4V0XA 2V88A 5IWAE 2MDRA 2YT4A 4BBYA 1XNRE 2KKNA 2P6BA 5KL6A 4LF5E 1OI8A 1EKZA 1Z2XA 4JI6E 4Q7FA 2FV4B 3IVDA 3IB8A 3F6GA 4JA7A 4RH8A 4LF7E 4R2CA
chains in the Genus database with same CATH topology
1S70A 1QHWA 3LL8A 1T71A 2IE4C 3T1IA 4I5NC 1HO5A 2WDDA 3E7BA 1NNWA 4H2IA 3K7VC 4ZVZA 2IE3C 4O5GA 4M0VA 5J28A 2BQ8X 2ZOAA 1WARA 3EGGA 3H66A 3RL4A 1S3LA 3ZTVA 2GJUA 2QFPA 3RL5A 2O8AA 2JOGA 2NYMC 3E7AA 2BCDA 3P71C 5INBA 2Z1AA 3IB7A 2DFJA 3KBPA 2YVTA 4TUIA 1QFCA 1MF8A 1S3NA 5F3WA 3H63A 4H1SA 1USHA 4I5LC 1S95A 4KKZA 3H69A 1UF3A 2WDEA 2DXLA 3PSNA 3DSCA 3DSDA 1HP1A 3N5UA 2QFRA 1OIDA 4H1YP 2BDXA 2ZO9B 2HY1A 4B2OA 1SU1A 5C1VA 3GVEA 4ZX2A 3DW8C 1XZWA 4FBQA 2IAEC 4YKEA 3D03A 4ORBA 4O4KA 3FGAC 3FLOA 3QG5C 4FBWA 4OR9A 2NPPC 4JA9A 4KBPA 4MOYA 5GTUA 2WDCA 2ZBMA 5JJTA 4DHLA 2QJCA 1OIEA 4DSYA 1IT6A 3EGHA 3V4YA 3K7WC 1V73A 1HPUA 1S8EA 1FJMA 4HD0A 1WAO1 4LTYA 3RL3A 3HVQA 4UT3A 2A22A 2HYPA 4MP0A 5DNYA 2Q8UA 4V0WA 4UT2A 4WWLA 4XPNA 4H2BA 3H68A 2Z72A 4H2FA 2USHA 3C5WC 3QFNA 3JYFA 3H67A 4FBKA 3RQZA 4ORAA 2WDFA 4J6OA 3H60A 4TUGA 1TCOA 2YEQA 4UT3B 1Z2WA 2R17A 4O43A 5B8IA 3AUZA 3C9FA 3PSOA 4LACC 5HPEA 3THNA 1T70A 3QFMA 2Z06A 2DXNA 3ICFA 3AV0A 1S3MA 4G9JA 3E0JA 3CK2A 4LU9A 4ORCA 3TGHA 1JK7A 4UWQA 1G5BA 3H61A 4NZVA 4IL1A 3H62B 1M63A 3H64A 2AHDA 3IVEA 4H2GA 2O8GA 4V0XA 4DT2A 2NYLC 3QFKA 1XM7A 5JPEA 5EQVA 4MOVA 2KKNA 1UTEA 2P6BA 2NXFA 3ZU0A 2XMOA 1W24A 2HYOA 4O24A 4F0ZA 2CV9A 1OI8A 1U32A 5JPFA 1Z2XA 4V0VA 4IYPC 4FCXA 1II7A 1KBPA 4Q7FA 3IVDA 3QFOA 3IB8A 1AUIA 4JA7A 5IOHA 3THOB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1S70 A;  1QHW A;  3LL8 A;  1T71 A;  2IE4 C;  3T1I A;  4I5N C;  1HO5 A;  2WDD A;  3E7B A;  1NNW A;  4H2I A;  3K7V C;  4ZVZ A;  2IE3 C;  4O5G A;  4M0V A;  5J28 A;  2BQ8 X;  1WAR A;  3EGG A;  3H66 A;  3RL4 A;  1S3L A;  3ZTV A;  2GJU A;  2QFP A;  3RL5 A;  2O8A A;  2JOG A;  2NYM C;  3E7A A;  2BCD A;  3P71 C;  5INB A;  2Z1A A;  3IB7 A;  2DFJ A;  3KBP A;  2YVT A;  4TUI A;  1QFC A;  1MF8 A;  1S3N A;  5F3W A;  3H63 A;  4H1S A;  1USH A;  4I5L C;  1S95 A;  4KKZ A;  3H69 A;  1UF3 A;  2WDE A;  3PSN A;  3DSC A;  3DSD A;  1HP1 A;  3N5U A;  2QFR A;  1OID A;  4H1Y P;  2BDX A;  2HY1 A;  4B2O A;  1SU1 A;  5C1V A;  3GVE A;  4ZX2 A;  3DW8 C;  1XZW A;  4FBQ A;  2IAE C;  4YKE A;  4ORB A;  4O4K A;  3FGA C;  3QG5 C;  4FBW A;  4OR9 A;  2NPP C;  4JA9 A;  4KBP A;  4MOY A;  5GTU A;  2WDC A;  2ZBM A;  5JJT A;  4DHL A;  2QJC A;  1OIE A;  4DSY A;  1IT6 A;  3EGH A;  3V4Y A;  3K7W C;  1V73 A;  1S8E A;  1HPU A;  1FJM A;  4HD0 A;  1WAO 1;  4LTY A;  3RL3 A;  3HVQ A;  4UT3 A;  2A22 A;  2HYP A;  4MP0 A;  5DNY A;  2Q8U A;  4V0W A;  4UT2 A;  4WWL A;  4XPN A;  4H2B A;  3H68 A;  2Z72 A;  4H2F A;  2USH A;  3C5W C;  3QFN A;  3JYF A;  3H67 A;  4FBK A;  3RQZ A;  4ORA A;  2WDF A;  4J6O A;  3H60 A;  4TUG A;  1TCO A;  4UT3 B;  1Z2W A;  2R17 A;  4O43 A;  5B8I A;  3AUZ A;  3C9F A;  3PSO A;  4LAC C;  5HPE A;  3THN A;  1T70 A;  3QFM A;  2Z06 A;  3ICF A;  3AV0 A;  1S3M A;  4G9J A;  3CK2 A;  4LU9 A;  4ORC A;  3TGH A;  1JK7 A;  4UWQ A;  1G5B A;  3H61 A;  4NZV A;  4IL1 A;  3H62 B;  1M63 A;  3H64 A;  2AHD A;  3IVE A;  4H2G A;  2O8G A;  4V0X A;  4DT2 A;  2NYL C;  3QFK A;  1XM7 A;  5JPE A;  5EQV A;  4MOV A;  2KKN A;  1UTE A;  2P6B A;  2NXF A;  3ZU0 A;  2XMO A;  1W24 A;  2HYO A;  4O24 A;  4F0Z A;  2CV9 A;  1OI8 A;  1U32 A;  5JPF A;  1Z2X A;  4V0V A;  4IYP C;  4FCX A;  1II7 A;  1KBP A;  4Q7F A;  3IVD A;  3QFO A;  3IB8 A;  1AUI A;  4JA7 A;  5IOH A;  3THO B; 
#chains in the Genus database with same CATH topology
 4F6N A;  1NEI A;  3J81 C;  2JYA A;  2EOS A;  1BBG A;  2LTR A;  2JWO A;  1ZAA C;  2UXC E;  2IHR 1;  4O5G A;  3UK3 C;  5J28 A;  4DMI A;  1YUI A;  1IQS A;  2EMX A;  2EN3 A;  1YYK A;  3ZTV A;  4BHB A;  1KJK A;  2WBS A;  1G2F C;  2GJU A;  5ADZ A;  2KHX A;  2LBS B;  1T4L B;  2JOG A;  4MLQ A;  5INB A;  3IB7 A;  3KBP A;  2JR1 A;  2L3J A;  4M30 A;  2V87 A;  3HPZ A;  5F3W A;  4H1S A;  2LJH A;  2DGC A;  1G2D C;  1HNW E;  2LUQ A;  2VQF E;  2MDG A;  4DV5 E;  3DSC A;  3DSD A;  2NUG A;  3JU0 A;  1OID A;  2LRS A;  2BDX A;  4F9B B;  2ZO9 B;  2D9H A;  2YTJ A;  2EMG A;  4GKK E;  2RPC A;  2EQ3 A;  4JI3 E;  4YKE A;  1X49 A;  1MEY C;  2EPR A;  4WSG A;  2EOI A;  3QG5 C;  2DB2 A;  4JA9 A;  4MOY A;  1O0W A;  3C4T A;  2QJC A;  2EN6 A;  2ELY A;  2EP3 A;  5AC5 A;  3V4Y A;  1IMU A;  3K7W C;  1HPU A;  2CSH A;  4WXC A;  5DNY A;  2N8X A;  3EPH A;  2A25 A;  5AE2 A;  2JPA A;  2LV2 A;  1A1F A;  4JI7 E;  1A1H A;  4XPN A;  5FLX C;  2EMB A;  4H2F A;  2EM5 A;  3C5W C;  3H67 A;  4NXM E;  3IWC A;  2HC5 A;  1WXR A;  1X6H A;  2RS6 A;  4DUY E;  3C9F A;  5HPE A;  4F9A B;  3IWB A;  3OML A;  4JI8 E;  3EPK A;  2Z06 A;  2ODR C;  2EMW A;  2EPX A;  2EE8 A;  4JI2 E;  1QU6 A;  3E0J A;  3MHS C;  3LML A;  4LU9 A;  3LLH A;  3MHH C;  1ZR9 A;  2GPI A;  4UWQ A;  2L2K B;  2L6M A;  4NZV A;  1PKP A;  2KOU A;  1M63 A;  4R2D A;  2I13 A;  1KYQ A;  2HGH A;  2EMI A;  2EOE A;  2EPC A;  4DT2 A;  1LLM C;  4GKJ E;  1XM7 A;  5EQV A;  1AH5 A;  1UTE A;  2E5L E;  1FJG E;  3P1X A;  2UUB E;  1UN6 B;  4R8O A;  2EM9 A;  2EM7 A;  4NXN E;  3BID A;  2YRK A;  5LL6 R;  4V0V A;  2LTS A;  4ZYG A;  1IBM E;  4B3R E;  2FGG A;  3TQM A;  2V83 A;  4L5N C;  4M2Z A;  4DV2 E;  2EPO A;  1RQ0 A;  2LMZ A;  2LE2 A;  2EM4 A;  1T71 A;  4I5N C;  2EN2 A;  3EQ1 A;  2YTN A;  1PJS A;  3K7V C;  4F6M A;  2YSP A;  4M0V A;  4DR5 E;  4BS9 A;  2BQ8 X;  3H66 A;  3EGG A;  2YSO A;  1S3L A;  2EPM X;  3T1H E;  3RL5 A;  2R76 A;  5KL4 A;  4F9C B;  4Q35 B;  3E7A A;  1YFH A;  1YUJ A;  4IJD A;  2EOY A;  2RQL A;  3H09 A;  2UXD E;  2YVT A;  2N3G A;  4LF4 E;  4BC7 A;  2M4I A;  1TF3 A;  2LVH A;  4L8N A;  2DIX A;  4AQY E;  1IBL E;  5A6B A;  1J26 A;  2WCC 3;  3PSN A;  4LF8 E;  1TF6 A;  2J7J A;  2L2M A;  4F2J C;  5AE1 A;  2MC6 A;  2HY1 A;  4B2O A;  2E72 A;  1SU1 A;  4JI0 E;  1EH6 A;  2VF1 A;  3C6M A;  1XZW A;  4HTG A;  4O4K A;  3VYY A;  4FBW A;  2EOO A;  1EH8 A;  3VK6 A;  2EOX A;  5JJT A;  1NCS A;  4R2E A;  2LT7 A;  2EM6 A;  1F2I G;  4JYA E;  2ODR D;  1N33 E;  2EMA A;  1A1K A;  2JY9 A;  3RL3 A;  2KON A;  4LTY A;  4UT3 A;  2A22 A;  2EPK X;  2L8T A;  2EML A;  5A6K A;  5KL3 A;  4YY3 E;  1X48 A;  2WBT A;  4MLV A;  4R2P A;  4KHP E;  2EOZ A;  1Z1B A;  3QFN A;  3JYF A;  5A6J A;  4X9J A;  4FBK A;  4ORA A;  4WX9 A;  4DR6 E;  2B9D A;  5KL5 A;  2DMY A;  4JI1 E;  4LFA E;  1TCO A;  1JK2 A;  2YEQ A;  1N34 E;  1Z2W A;  4O43 A;  1BB8 A;  3PSO A;  4P7D A;  2RTX A;  4LAC C;  4M9V C;  1T70 A;  2ADR A;  4DR4 E;  4OX9 E;  1DI2 A;  4F54 A;  3RMP A;  3ICF A;  1UHZ A;  2YTD A;  1XNQ E;  2EOR A;  3JTZ A;  1WRJ A;  5AC4 A;  4LFC E;  2EJ4 A;  2EM0 A;  3H62 B;  2L33 A;  3H64 A;  4FK5 C;  4DKK A;  3EPJ A;  4DV4 E;  2EMY A;  2B3T B;  5A6B D;  1UIL A;  2CT1 A;  2NXF A;  5TSE A;  2XMO A;  1A1G A;  5KL2 A;  4I8O A;  2LO3 A;  2CV9 A;  2YTQ A;  4WPY A;  5KL7 A;  4X62 E;  1U32 A;  1YSA C;  4IYP C;  4FCX A;  2VE7 C;  1TN9 A;  1II7 A;  2V85 A;  3QFO A;  1AUI A;  2L92 A;  1T38 A;  1SFE A;  2EPN A;  3THO B;  4BCA A;  1P47 A;  4DV6 E;  5LMU E;  1QHW A;  4WSP A;  4BHC A;  1GZ6 A;  3T1I A;  1RC7 A;  5A6A A;  2UUA E;  5AAS A;  1NNW A;  1DQ3 A;  3BF2 A;  2IE3 C;  4ZVZ A;  2N3H A;  4K0K E;  4WFT A;  2ZOA A;  1WAR A;  3RL4 A;  4ZYE A;  1GTK A;  2O8A A;  2PRT A;  2EOM A;  2EZ6 A;  3P71 C;  2ZM6 E;  4DR1 E;  2Z1A A;  2M7Q A;  2VQE E;  1QFC A;  1MF8 A;  3OTO E;  4B3S E;  2GHF A;  3H63 A;  2EL5 A;  1USH A;  1A1L A;  2YU5 A;  1WJP A;  1YPN A;  1S95 A;  3ADI A;  1T4O A;  1JK1 A;  2NUE A;  2VRD A;  4LF6 E;  2WDE A;  2EPP A;  2B7T A;  1PDA A;  2YTO A;  2ENA A;  1XMO E;  1HP1 A;  3N5U A;  4DV3 E;  2E1M A;  2QFR A;  4H1Y P;  2EMK A;  2EMF A;  4R2R A;  3ADJ A;  3GVE A;  2JOX A;  4FBQ A;  2JOB A;  1ZU1 A;  4RHB B;  1BBO A;  2CTD A;  4OR9 A;  5GTU A;  2DLK A;  2WDC A;  2ZBM A;  2EOF A;  4DHL A;  5IV8 B;  4DSY A;  1A1I A;  2EQ1 A;  2DRP A;  4R2Q A;  3ADL A;  3KZY A;  1UBD C;  1V73 A;  1FJM A;  4HD0 A;  2L2N A;  3JAM C;  3HPS A;  4MP0 A;  2V8Q B;  4KWY A;  2MC5 A;  2EL6 A;  5A69 A;  4UT2 A;  2ENC A;  4WWL A;  4H2B A;  2YTG A;  3DJW A;  2Z72 A;  1X47 A;  2JVA A;  1DGC A;  4DV1 E;  3RQZ A;  2YWQ A;  2NA2 A;  3H60 A;  4TUG A;  3J7Y p;  2F4V E;  2R17 A;  5B8I A;  4BC9 A;  4P78 A;  3AUZ A;  2B7V A;  4BMJ A;  2BBG A;  1IBK E;  3QFM A;  2DXN A;  1GQE A;  1T4N A;  2R1F A;  1N32 E;  3CK2 A;  2EN7 A;  1G5B A;  3H61 A;  4IL1 A;  5IT9 C;  2JXP A;  2LUP B;  4B3T E;  4KZS A;  4LFB E;  2EQ0 A;  1SR9 A;  2AHD A;  1MGT A;  3IVE A;  5LMN E;  4H2G A;  3HQ1 A;  3IWD A;  2NYL C;  3QFK A;  5AE3 A;  5JPE A;  4MOV A;  4NHR A;  2DMI A;  3ZU0 A;  2HHH E;  4GEQ B;  1W24 A;  2RSM A;  2HYO A;  4O24 A;  1N3G A;  1J5E E;  4F0Z A;  2ELZ A;  5JPF A;  2YTP A;  3C4B A;  4OOG C;  4YHH E;  2EMZ A;  1KBP A;  2MKN A;  2WZO A;  2EMH A;  2EOQ A;  1ZBQ A;  5IOH A;  2YPN A;  4V0W A;  4DUZ E;  4DR3 E;  1S70 A;  1STU A;  3LL8 A;  1B69 A;  2WBU A;  2IE4 C;  2H36 X;  1HO5 A;  2WDD A;  3E7B A;  2EM8 A;  3C6K A;  3VYX A;  4H2I A;  2NAB A;  3BGH A;  2EOJ A;  2YTE A;  3T1Y E;  1FKA E;  2UXB E;  4DV0 E;  4DR2 E;  1ZBT A;  2EN8 A;  1AAY A;  4JI4 E;  2QFP A;  2F8B A;  2YU8 A;  1RMD A;  4R2S A;  2YTI A;  1I94 E;  1A1J A;  2NYM C;  2BCD A;  5IXM B;  2EWL A;  5A2Q C;  4DR7 E;  2EN4 A;  2DFJ A;  4TUI A;  3K6Q A;  5CFF E;  3J80 C;  1S3N A;  2EN1 A;  3L00 A;  5T6J A;  1L4S A;  4J8Z A;  1T39 A;  1HR0 E;  4WYQ B;  4I5L C;  4KKZ A;  3H69 A;  3ECR A;  3VHT B;  2FTX B;  2EM3 A;  4B3M E;  1UF3 A;  2MKD A;  2DXL A;  1X3C A;  1HNZ E;  4HEI A;  2GLI A;  3FIG A;  4JI5 E;  3F6H A;  2CPN A;  4R03 A;  1N36 E;  2UUC E;  1X6F A;  1WHN A;  2ENH A;  5C1V A;  4ZX2 A;  4X65 E;  1WHQ A;  2G7H A;  3DW8 C;  2DSY A;  2IAE C;  2EPA A;  3HXL A;  4LF9 E;  3D03 A;  3FGA C;  4ORB A;  3FLO A;  3M99 B;  2EPU A;  2NPP C;  4KBP A;  5LLQ A;  1PJT A;  3ZOQ B;  1OIE A;  1QNT A;  1IT6 A;  3EGH A;  2DLQ A;  3EPL A;  1XMQ E;  4ZYH A;  4IS1 C;  3KZZ A;  2EPL X;  1S8E A;  2YZT A;  2EL4 A;  4X8W A;  4Q28 A;  1WAO 1;  3HVQ A;  2HYP A;  4DV7 E;  2EOH A;  2V89 A;  1HNX E;  2Q8U A;  2M1S A;  2LJU A;  4GZN C;  3H68 A;  1IQO A;  2EPZ A;  4JV5 E;  4X66 E;  2USH A;  2JP9 A;  2RS7 A;  2YRM A;  1YYW A;  2WDF A;  4J6O A;  2YTF A;  3BBG A;  3MSW A;  2NUF A;  2EM2 A;  2V86 A;  4UT3 B;  2BB8 A;  4X64 E;  4N4R B;  1X5W A;  2HJJ A;  3THN A;  4ZYD A;  3J7A G;  3AV0 A;  2EMC A;  2L3C A;  1S3M A;  3KWR A;  4G9J A;  4ORC A;  2RSI A;  3TGH A;  2K4V A;  1PJQ A;  4R2A A;  1JK7 A;  1YZ9 A;  3DF6 A;  1YYO A;  4WXD A;  1EH7 A;  2M9A A;  3HTX A;  2K7I A;  2YRH A;  2UU9 E;  2I9I A;  1X6E A;  2LCE A;  2O8G A;  3ADG A;  5BR8 E;  4V0X A;  2V88 A;  5IWA E;  2MDR A;  2YT4 A;  4BBY A;  1XNR E;  2KKN A;  2P6B A;  5KL6 A;  4LF5 E;  1OI8 A;  1EKZ A;  1Z2X A;  4JI6 E;  4Q7F A;  2FV4 B;  3IVD A;  3IB8 A;  3F6G A;  4JA7 A;  4RH8 A;  4LF7 E;  4R2C A; 
#chains in the Genus database with same CATH homology
 1S70 A;  1QHW A;  3LL8 A;  1T71 A;  2IE4 C;  3T1I A;  4I5N C;  1HO5 A;  2WDD A;  3E7B A;  1NNW A;  4H2I A;  3K7V C;  4ZVZ A;  2IE3 C;  4O5G A;  4M0V A;  5J28 A;  2BQ8 X;  2ZOA A;  1WAR A;  3EGG A;  3H66 A;  3RL4 A;  1S3L A;  3ZTV A;  2GJU A;  2QFP A;  3RL5 A;  2O8A A;  2JOG A;  2NYM C;  3E7A A;  2BCD A;  3P71 C;  5INB A;  2Z1A A;  3IB7 A;  2DFJ A;  3KBP A;  2YVT A;  4TUI A;  1QFC A;  1MF8 A;  1S3N A;  5F3W A;  3H63 A;  4H1S A;  1USH A;  4I5L C;  1S95 A;  4KKZ A;  3H69 A;  1UF3 A;  2WDE A;  2DXL A;  3PSN A;  3DSC A;  3DSD A;  1HP1 A;  3N5U A;  2QFR A;  1OID A;  4H1Y P;  2BDX A;  2ZO9 B;  2HY1 A;  4B2O A;  1SU1 A;  5C1V A;  3GVE A;  4ZX2 A;  3DW8 C;  1XZW A;  4FBQ A;  2IAE C;  4YKE A;  3D03 A;  4ORB A;  4O4K A;  3FGA C;  3FLO A;  3QG5 C;  4FBW A;  4OR9 A;  2NPP C;  4JA9 A;  4KBP A;  4MOY A;  5GTU A;  2WDC A;  2ZBM A;  5JJT A;  4DHL A;  2QJC A;  1OIE A;  4DSY A;  1IT6 A;  3EGH A;  3V4Y A;  3K7W C;  1V73 A;  1HPU A;  1S8E A;  1FJM A;  4HD0 A;  1WAO 1;  4LTY A;  3RL3 A;  3HVQ A;  4UT3 A;  2A22 A;  2HYP A;  4MP0 A;  5DNY A;  2Q8U A;  4V0W A;  4UT2 A;  4WWL A;  4XPN A;  4H2B A;  3H68 A;  2Z72 A;  4H2F A;  2USH A;  3C5W C;  3QFN A;  3JYF A;  3H67 A;  4FBK A;  3RQZ A;  4ORA A;  2WDF A;  4J6O A;  3H60 A;  4TUG A;  1TCO A;  2YEQ A;  4UT3 B;  1Z2W A;  2R17 A;  4O43 A;  5B8I A;  3AUZ A;  3C9F A;  3PSO A;  4LAC C;  5HPE A;  3THN A;  1T70 A;  3QFM A;  2Z06 A;  2DXN A;  3ICF A;  3AV0 A;  1S3M A;  4G9J A;  3E0J A;  3CK2 A;  4LU9 A;  4ORC A;  3TGH A;  1JK7 A;  4UWQ A;  1G5B A;  3H61 A;  4NZV A;  4IL1 A;  3H62 B;  1M63 A;  3H64 A;  2AHD A;  3IVE A;  4H2G A;  2O8G A;  4V0X A;  4DT2 A;  2NYL C;  3QFK A;  1XM7 A;  5JPE A;  5EQV A;  4MOV A;  2KKN A;  1UTE A;  2P6B A;  2NXF A;  3ZU0 A;  2XMO A;  1W24 A;  2HYO A;  4O24 A;  4F0Z A;  2CV9 A;  1OI8 A;  1U32 A;  5JPF A;  1Z2X A;  4V0V A;  4IYP C;  4FCX A;  1II7 A;  1KBP A;  4Q7F A;  3IVD A;  3QFO A;  3IB8 A;  1AUI A;  4JA7 A;  5IOH A;  3THO B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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