4BPMA

Crystal structure of a human integral membrane enzyme
Total Genus 66
204060801001201401600102030405060
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
162
structure length
162
Chain Sequence
SPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHFLPAALRAALLGRLRTLRPW

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
AH1 (11-41)AH3 (63-91)AH4 (96-119)AH2 (47-53)3H1 (56-58)AH5 (124-151)AH6 (155-161)EMPTYUpdating...
connected with : NaN
molecule tags Isomerase
source organism Homo sapiens
publication title Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy.
pubmed doi rcsb
molecule keywords PROSTAGLANDIN E SYNTHASE, FUSION PEPTIDE
total genus 66
structure length 162
sequence length 162
ec nomenclature ec 4.4.1.20: Leukotriene-C(4) synthase.
pdb deposition date 2013-05-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01124 MAPEG MAPEG family
A PF01124 MAPEG MAPEG family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.550 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Membrane associated eicosanoid/glutathione metabolism-like domain 4bpmA00
4NTBA 4JCZA 4J7TA 3HKKA 5BQHA 3LEOA 3PCVA 2Q7RA 5HV9A 4J7YA 4JRZA 4WABA 4AL1A 4NTFA 4NTAA 4BPMA 2PNOA 4JC7A 4YL3A 4YL0A 4YL1A 4AL0A 2H8AA 4YK5A 2UUHA 2UUIA 5BQIA 3B29A 3DWWA 5BQGA 5K0IA
chains in the Genus database with same CATH superfamily
1EA8A 1QPUA 3IHUA 2A69F 5AC5A 1YLMA 3LJBA 2A6EF 2XRHA 3AQCA 3Q7GA 1I5NA 4KNVA 4XEKA 2R7UA 3C8GD 2R7TA 1FNTc 4DJ9A 4NCQA 2QE9A 1BR4A 2Q9CA 2J45A 1Z63A 1O3UA 3SZRA 2XXAA 3A11A 4N6HA 4XEFA 1U0BB 2XL8A 4C7OA 2UUIA 3WAQA 1I4YA 3B0UX 2LP4A 2J9VA 1Z5ZA 2MHRA 2QNLA 2Y39A 2XLHA 2YL1A 2YL7A 3GM1A 3X1OA 2J0WA 4BJTA 5KYWB 5L0IA 1C02A 3O55A 4WJ0A 2XLEA 5DS4A 2AVKA 5L0FA 3U3BA 2J7PA 1PD1A 4XPYA 4JEAA 1RJ9A 2R7WA 1HW2A 3PCVA 2A0BA 3NKEA 4FX5A 4MVZA 4GYTA 2A0UA 2VCAA 4J7YA 2VH3A 4KNWA 4PJLA 2PBEA 3GWNA 3NYJA 5DS5A 4DVZA 1ZHYA 1N1CA 2EPMX 4MVUA 1VYIA 2X51A 3F46A 4MVRA 4A4AA 3O6XA 3SXZA 4E18A 1EQ1A 2VCCA 5DVWA 3RFYA 2IM8A 2Y3GA 5DQZA 3L1MA 1D1CA 3HTKC 3U2MA 4XLNF 3C8ZA 4MTOA 1HE1A 3H2UA 4ONSA 3SNHA 4AE4B 3U2LA 4CS8A 3N2ZB 5KYYB 5DS6A 1A0BA 1QZXA 4U5HA 3EGXB 4QI2A 3B29A 2PX3A 2W4MA 3GM3A 4E0IA 3NYLA 2FGYA 2Y3HA 4Z9JA 4D4NA 1PV3A 1Q0MA 1QSPA 1YARO 2R7OA 5K0IA 3K7DA 3WODF 2W45A 3MYIA 2ZD9A 5E33A 1NFNA 3OWTA 3UNGC 3ZTZA 4U5EE 1YYXA 3FAPB 4BJ5C 1YVIA 2NUPB 2EPOA 1HE9A 5JSLA 4YT2A 5KYUB 1D1AA 2ZXPA 1WASA 2YHSA 4H54A 3N0TA 1H6GA 3EHNA 4HFKB 1A41A 1WATA 2Q9BA 4O6NA 3E9VA 2VASA 4A2NB 3I4UA 2BE5F 5JUAA 3LUTB 1VK5A 1LS4A 1FAPB 4DBRA 3K6BA 3DI5A 2HSQA 1ZU4A 3JTLO 3QW0A 2ETSA 1LM3B 1VLTA 3JSZA 1CGOA 4QI0A 5B1AC 3T9OA 2WZGA 3G50A 3LESA 1YA7O 2YLIA 4FWVA 1KNYA 3DKAA 3HNKA 4MVOA 3MFNA 2GAQA 3H2VA 4YT8A 1W2WA 4CSAA 4WGYA 2DYRC 4IARA 3QW1A 1UFBA 1OCZC 5JS5A 1JPJA 3SXYA 1VTMP 4PFOA 3B0PA 3TJ6A 1ZHWA 4YL3A 5A6KA 5L3VA 3RH3A 1NLXA 1ORSC 1E85A 3E70C 4OIRF 2A68F 2LIGA 1Q0GA 2AP3A 2WZFA 2RSEB 3GODA 3L8JA 3GEEA 3IQ5A 1AVOB 1WOLA 1Y6DA 3C8GB 1WWPA 1RXQA 2J46A 3RQGA 1EI7A 3A9CA 3CAXA 3EGDA 4J30B 4JTDB 1ZW3A 2XS8A 3I5QA 4CIHA 4JTAB 4JEBA 4NTBA 2AU5A 4P9FA 3UMKA 1VOMA 4JCZA 4YJWA 1SYQA 2OQMA 4KI2A 2NUTB 4M63A 4IAQA 2GWWA 1HMDA 4JIOA 4K1OA 3IPMO 4XEVA 4ER9A 4JJGA 1V74B 2IBFA 1LPEA 4QDLA 3U9JA 1TFOB 3U8VA 3DJNB 1Z23A 4C3BA 1A7EA 2J0XA 2LD6A 4IB4A 3JSEO 1RMVA 4U5FE 4P6IC 4G7OF 3AGTA 4N4WA 5B3SC 1C17M 1TWHA 1LVKA 2KJGA 4YL1A 3ITFA 4BJ6C 2RD9A 1S7ZA 3O39A 3QMKA 2XXAB 3NDBB 1M57C 1SF8A 3RW0A 2LSEA 3JT1A 2HS5A 1KTMA 3NG1A 1LIHA 1NBBA 1T6QA 2P6VA 3ABKC 3TQOA 4C7OB 4OD4A 2B0HA 3JYHA 1FMVA 4ANJA 2KSFA 2A1DD 1XZQA 2XL4A 3C63A 2WVNA 2CDQA 3DM5A 3NRHA 4W8KA 3S27A 2YRFA 3HNJA 3SP1A 1Z6AA 3EZHA 1M2VA 4MTFA 2D4UA 4I1OB 4D4XA 1RJ9B 1J8MF 3UMHA 4CS9A 4NTFA 4XPWA 2HJ3A 4BPMA 4FAPB 2G3VA 1DOVA 1LI5A 2KGOA 3DE8A 3I5PA 4OIQF 2XM4A 4XWJA 2L81A 3V5XA 1SZIA 4RBNA 1HW1A 1ORJA 1ZYRF 3EH1A 4U9DA 2QTVA 4AK9A 5HSWA 1MMNA 3DAFA 1GGQA 1ZW2A 3X2QC 1T01A 2KW3C 3MLGA 1ORYA 2PFDA 2JX0A 2FFHA 1ZHTA 2EPLX 1CPRA 4H4KC 1T6UA 5E3CA 2L6FA 3DMDA 3FAJA 4NC3A 3VRCA 3VYWA 2DB4A 2KK1A 1DOWA 4IAOA 1WN0A 4N06A 4FESA 2L6GA 2X0CA 5BUOA 3ZTMA 2MWQA 4B6IA 4CS7A 1M2OA 4YT4A 2PX0A 2PP4A 2OCCC 2QUPA 4ZLCA 4CSAC 1D0YA 1U6HA 4GQHA 4YL0A 4CIPA 1BZ4A 3N24A 3M4CA 4W8PA 2HMQA 5E2QA 3AJMA 1KU2A 4U5CE 1L3PA 2QLAA 1ZHXA 3MYFA 3ZG1A 2IXMA 3QZCA 4PJMA 3TOLA 2J7PD 5T3TA 2HV7A 4U5GA 1FFHA 2OEXA 3EJNA 1JPNA 3ZQVA 1V55C 3LNMB 3V5ZA 3FXHA 2LCHA 1AUEA 4K0DA 3DZAA 2ZXOA 4G78A 1TKNA 2EPNA 3QVYA 1J8YF 2H7VC 3CZ6A 3AG3C 3BRJA 2P0NA 1WTYA 1O5HA 3QVZA 4IGGA 5COFA 4CDVA 5JT4A 2R7SA 2EIKC 2H7BA 2I15A 1MMGA 3EZIA 3LEOA 1YZCA 3U9MA 1FTSA 2NPUA 4DOZA 1OCCC 1NG1A 2YEVA 4E7SA 3H65A 2J9UA 3Q6NA 5CIVA 4E17A 1TWGA 4EUKB 4DRJB 2C03A 4N6CA 3JYYA 3M79A 5JRAA 3FOPA 1H7IA 1TWCA 2P1AA 2XSEA 3M1CB 1FMWA 4MNDA 3UMIA 5D91A 3PDMP 3RKOF 4G7ZF 1SR2A 2Y69C 2Q9AA 4MW3A 3Q7LA 1UG7A 2YQYA 1YZAA 5JLIA 1ZZPA 2YLGA 4F4BA 2BL2A 4GEHA 1LKXA 2XM0A 4CJOA 3CSKA 4JVSA 3EHMA 1TWAA 3B9QA 2B0JA 4EBJA 5BQHA 2EPKX 3W8IA 3ZVRA 1JOGA 1LS1A 1U89A 3KYIA 4IJJA 1XZPA 3EGDB 4XPXA 1A7VA 2CW0F 1YA9A 1OW8A 2EINC 3U8PA 1T5OA 4DRHB 2KYHA 5KYXB 2CGEA 3ASOC 3T6JA 3GM2A 5F28E 4EKWA 3RVZA 4CBEA 3OEOA 4EHPA 1MMDA 4LACB 1AEPA 2M4EA 3EFOA 1GQAA 1TFKB 5EGYA 1G4US 1T9KA 2ZXRA 2WL8A 2L6HA 2YKZA 4DRIB 1K40A 2R9RB 2OJED 3LLIA 4JKVA 4WGZA 3S9OA 3VF0A 4CDAA 3ZIBA 4RDAA 1D1BA 2IOQA 2YL0A 3TD7A 2R25A 3F47A 3G4ZA 5FZTA 3RYLA 2XLOA 2XLVA 5COGA 3T4RA 1T6IA 3W2WA 1YAUO 2NUPA 1BBHA 2HUJA 2F22A 1V54C 3EG9B 3ZDLA 5DLJA 1Q0KA 1Y4CA 1RKEA 1K04A 5AC4A 1A7DA 3GEIA 3ECSA 3M4BA 4ZLDA 1M2VB 3HNLA 4XQ1A 2LFFA 2L7AA 4ULWA 2PNOA 2H7OA 3MX3A 2ZXWC 4JC7A 3G4XA 5B1BC 4C3DA 3GORA 5DQTA 1TR2A 4AX2A 3L34A 1JMWA 1QKRA 4YT5A 4LDKA 3L0IA 3NYMA 2HFIA 2C04A 2EIMC 3GEHA 3AG1C 1PCXA 3K1IA 1B68A 3S90A 2UUHA 1QLEC 3DJUB 2HMZA 5A6JA 2ASRA 4P9TA 4EBBA 4BJ5A 1G5ZA 1VMAA 1G4WR 2M64A 3EPVA 2Y3BA 2TMVP 3KMIA 3U0CA 4BEJA 2QY9A 3FOOA 4U5BE 1ZHZA 1OKKA 3IQ6A 1E2XA 1Z7Qc 4CS8C 3IQCA 4X0RA 4L6RA 1QVXA 1NFOA 3NMIA 4O7GA 1APCA 3KL4A 5L3QA 2AWCA 3J06A 3GWLA 2Q7RA 4BG0A 5L0JA 1ZVZA 4HFFB 4AL1A 4LLCA 4KC9A 1OXBA 3LS0A 2Q00A 2Q4FA 3FDQA 3S0XA 3KPHA 1BR2A 2HJMA 1NZEA 2IXOA 4J32B 4Z9IA 3W4YA 4XLPF 3U5SA 1E83A 3WG7C 4OIOF 4JCHA 4AL0A 3K66A 4PJNA 5JVEA 2LQGA 2P61A 4PACA 2Y3DA 1JR8A 1MMAA 3LLKA 5F5HA 2PF4E 4LDQA 3UGOA 1EKYA 1HMOA 1S05A 2OU6A 2YWAA 3FHDA 2BC5A 4YN0B 1VYKA 2XLWA 4MQ9F 2ICWG 3T6BA 4EWCA 2L9JA 4I3MA 4CDYA 1IZMA 1BDJB 1Q0FA 3ATPA 3JRTA 1V4AA 3K33A 2HZ8A 4JRZA 4ULVA 2R03A 4WABA 2J8WA 5A6BA 3JRMO 5T1DB 2VB6A 3S28A 2EILC 2KNHA 1TQGA 3ZWIA 3AQBA 4DXWA 4MW8A 5EHHA 3LAYA 1MQVA 1MNEA 2CNWA 3UGPA 2KC3A 1NU9C 2YVKA 4DVYP 3TK0A 4MVMA 5AGFA 3NMKA 1XWJA 3ABLC 4RD9A 1ST6A 2J9BA 5BQIA 3WHNA 2VCBA 3AOUA 3QTHA 5COMA 5A6BD 2HKVA 3CEXA 1D0XA 1MNDA 2IYLD 2XS1A 4IWBA 4Q7CA 5B3IA 2OJQA 4OINF 2CNWD 4EIYA 3C7JA 3S29A 1WGWA 4BJ6A 256BA 2HSBA 2OG2A 3TJ5A 4BEMJ 3T6GB 5A69A 4U5DE 4PR9A 2GFHA 1HY5A 1R5ID 2NSFA 3V7OA 2AWYA 1YYJA 2V26A 1OXKA 3EH2A 3TOMA 2G62A 2DYSC 2W9YA 3RQFA 1ZU5A 1K05A 3SXKA 3VAYA 4CJGA 1F1MA 1NU7D 1RCPA 2YLDA 3ZSUA 4O6YA 2LFDA 4Q4ZF 3DD7A 1CGNA 4CX9A 4EBKA 3NKDA 3EFOB 4OIPF 1G8XA 4KBLA 3IQTA 3L8IA 2H8AA 4HE8D 2R7QA 3RF3A 2CCYA 3B0VC 5KYWA 2V3CC 1QQ3A 3HNIA 3KKBA 4Z9HA 3R2PA 3V5YA 2XLDA 3S84A 3ASNC 4YWQA 2EIJC 1L7CA 2R05A 4G0HA 4JZAA 2I8BA 5D92A 3SXMA 5IY5C 1R4TA 3DM9B 3GANA 5BQGA 3PHF2 3K1IC 1FR0A 4K7BA 1JAFA 2XLMA 3LEVA 3AG4C 4OD5A 2D5RB 1BR1A 1RKEB 3HLZA 4NTAA 2YL3A 5CI8A 3RQEA 2XL6A 5A6AA 1E84A 2WVQA 1CGME 3AGUA 3HJCA 1Q0DA 2JPUA 3MBGA 5KYNA 3ZQYA 1GM5A 3Q6MA 1E86A 4AE4A 3FMSA 2GA0A 1RKCA 1OR3A 4G7HF 5KYYA 5TJ5E 4MS2A 1CPQA 1SMYF 2GDCA 3EGXA 3K1HA 4YK5A 4BJ1A 4CS9C 1OQCA 2NSGA 5L0DA 5L0GA 4UDVA 3IEEA 4JW1A 5T3WA 1NSGB 1C03A 2IXNA 1OR2A 3US6A 2JD3A 1D0ZA 1M6TA 2J9WA 1M56C 2Q3TA 4I44A 4MVQA 2P7VA 5KYUA 2W4BA 4J7TA 1FFTC 2OOCA 2WB7A 3HKKA 3R7CA 3VM6A 5L0HA 4U9EA 2A6HF 4LDRA 4O6MA 2WZLA 2ZPAA 1H9TA 2VC9A 4IRUA 3SYNA 4JE9A 2G3KA 5JP7A 2CYDA 2DI3A 1YDIA 3POVA 2YZSA 3DAGA 2R7XA 2HV6A 1JRAA 3DE9A 3FVYA 5E3AA 3NMJA 3EQLF 2OEVA 4R32A 3KH2A 2DGJA 3ABMC 1OCOC 2FAPB 1Z3IX 3OA1A 1GS9A 1PD0A 1H9GA 3ZC4A 3SEOA 4MTGA 2E87A 3DWWA 1LE4A 2WVOA 3TULA 5FCLA 3O10A 4PK4A 5GPGB 3RIPA 4JTCB 4Q5SF 5KYXA 2O9XA 2Z15A 5EK0A 1I4ZA 4E0HA 4NY3A 3LS1A 5CI9A 4PFPA 2OKUA 4E7ZA 3AG2C 3KYJA 3M15A 1OW7A 5HV9A 2IXPA 5F5FA 2R02A 1VLSA 5L0CA 1VB5A 2NG1A 3U3FA 4LLEA 1IW7F 4MVSA 3DXJF 4C3EA 3UR3C 4DBQA 3CQZA 3JCUQ 3BEHA 2R7VA 4PJJA 1LI7A 1OKKD 3C8GA 4HEAJ 3RVYA 3W8HA 1LE2A 1OW6A 4JJFA 2KQ9A 3PMRA 1O87A 2MYSA 4JURI 3JZ0A 3B71A 3EG9A 1OCRC 4I1MA 3C62A 2LK4A 1YJGA 4LERA 4O79A 4NQFA 4XTKA 3C18A 3LNRA 3W2VA 2NUTA 2R7RA
chains in the Genus database with same CATH topology
4NTBA 4JCZA 4J7TA 3HKKA 5BQHA 3LEOA 3PCVA 2Q7RA 5HV9A 4J7YA 4JRZA 4WABA 4AL1A 4NTFA 4NTAA 4BPMA 2PNOA 4JC7A 4YL3A 4YL0A 4YL1A 4AL0A 2H8AA 4YK5A 2UUHA 2UUIA 5BQIA 3B29A 3DWWA 5BQGA 5K0IA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4NTB A;  4JCZ A;  4J7T A;  3HKK A;  5BQH A;  3LEO A;  3PCV A;  2Q7R A;  5HV9 A;  4J7Y A;  4JRZ A;  4WAB A;  4AL1 A;  4NTF A;  4NTA A;  4BPM A;  2PNO A;  4JC7 A;  4YL3 A;  4YL0 A;  4YL1 A;  4AL0 A;  2H8A A;  4YK5 A;  2UUH A;  2UUI A;  5BQI A;  3B29 A;  3DWW A;  5BQG A;  5K0I A; 
#chains in the Genus database with same CATH topology
 1EA8 A;  1QPU A;  3IHU A;  2A69 F;  5AC5 A;  1YLM A;  3LJB A;  2A6E F;  2XRH A;  3AQC A;  3Q7G A;  1I5N A;  4KNV A;  4XEK A;  2R7U A;  3C8G D;  2R7T A;  1FNT c;  4DJ9 A;  4NCQ A;  2QE9 A;  1BR4 A;  2Q9C A;  2J45 A;  1Z63 A;  1O3U A;  3SZR A;  2XXA A;  3A11 A;  4N6H A;  4XEF A;  1U0B B;  2XL8 A;  4C7O A;  2UUI A;  3WAQ A;  1I4Y A;  3B0U X;  2LP4 A;  2J9V A;  1Z5Z A;  2MHR A;  2QNL A;  2Y39 A;  2XLH A;  2YL1 A;  2YL7 A;  3GM1 A;  3X1O A;  2J0W A;  4BJT A;  5KYW B;  5L0I A;  1C02 A;  3O55 A;  4WJ0 A;  2XLE A;  5DS4 A;  2AVK A;  5L0F A;  3U3B A;  2J7P A;  1PD1 A;  4XPY A;  4JEA A;  1RJ9 A;  2R7W A;  1HW2 A;  3PCV A;  2A0B A;  3NKE A;  4FX5 A;  4MVZ A;  4GYT A;  2A0U A;  2VCA A;  4J7Y A;  2VH3 A;  4KNW A;  4PJL A;  2PBE A;  3GWN A;  3NYJ A;  5DS5 A;  4DVZ A;  1ZHY A;  1N1C A;  2EPM X;  4MVU A;  1VYI A;  2X51 A;  3F46 A;  4MVR A;  4A4A A;  3O6X A;  3SXZ A;  4E18 A;  1EQ1 A;  2VCC A;  5DVW A;  3RFY A;  2IM8 A;  2Y3G A;  5DQZ A;  3L1M A;  1D1C A;  3HTK C;  3U2M A;  4XLN F;  3C8Z A;  4MTO A;  1HE1 A;  3H2U A;  4ONS A;  3SNH A;  4AE4 B;  3U2L A;  4CS8 A;  3N2Z B;  5KYY B;  5DS6 A;  1A0B A;  1QZX A;  4U5H A;  3EGX B;  4QI2 A;  3B29 A;  2PX3 A;  2W4M A;  3GM3 A;  4E0I A;  3NYL A;  2FGY A;  2Y3H A;  4Z9J A;  4D4N A;  1PV3 A;  1Q0M A;  1QSP A;  1YAR O;  2R7O A;  5K0I A;  3K7D A;  3WOD F;  2W45 A;  3MYI A;  2ZD9 A;  5E33 A;  1NFN A;  3OWT A;  3UNG C;  3ZTZ A;  4U5E E;  1YYX A;  3FAP B;  4BJ5 C;  1YVI A;  2NUP B;  2EPO A;  1HE9 A;  5JSL A;  4YT2 A;  5KYU B;  1D1A A;  2ZXP A;  1WAS A;  2YHS A;  4H54 A;  3N0T A;  1H6G A;  3EHN A;  4HFK B;  1A41 A;  1WAT A;  2Q9B A;  4O6N A;  3E9V A;  2VAS A;  4A2N B;  3I4U A;  2BE5 F;  5JUA A;  3LUT B;  1VK5 A;  1LS4 A;  1FAP B;  4DBR A;  3K6B A;  3DI5 A;  2HSQ A;  1ZU4 A;  3JTL O;  3QW0 A;  2ETS A;  1LM3 B;  1VLT A;  3JSZ A;  1CGO A;  4QI0 A;  5B1A C;  3T9O A;  2WZG A;  3G50 A;  3LES A;  1YA7 O;  2YLI A;  4FWV A;  1KNY A;  3DKA A;  3HNK A;  4MVO A;  3MFN A;  2GAQ A;  3H2V A;  4YT8 A;  1W2W A;  4CSA A;  4WGY A;  2DYR C;  4IAR A;  3QW1 A;  1UFB A;  1OCZ C;  5JS5 A;  1JPJ A;  3SXY A;  1VTM P;  4PFO A;  3B0P A;  3TJ6 A;  1ZHW A;  4YL3 A;  5A6K A;  5L3V A;  3RH3 A;  1NLX A;  1ORS C;  1E85 A;  3E70 C;  4OIR F;  2A68 F;  2LIG A;  1Q0G A;  2AP3 A;  2WZF A;  2RSE B;  3GOD A;  3L8J A;  3GEE A;  3IQ5 A;  1AVO B;  1WOL A;  1Y6D A;  3C8G B;  1WWP A;  1RXQ A;  2J46 A;  3RQG A;  1EI7 A;  3A9C A;  3CAX A;  3EGD A;  4J30 B;  4JTD B;  1ZW3 A;  2XS8 A;  3I5Q A;  4CIH A;  4JTA B;  4JEB A;  4NTB A;  2AU5 A;  4P9F A;  3UMK A;  1VOM A;  4JCZ A;  4YJW A;  1SYQ A;  2OQM A;  4KI2 A;  2NUT B;  4M63 A;  4IAQ A;  2GWW A;  1HMD A;  4JIO A;  4K1O A;  3IPM O;  4XEV A;  4ER9 A;  4JJG A;  1V74 B;  2IBF A;  1LPE A;  4QDL A;  3U9J A;  1TFO B;  3U8V A;  3DJN B;  1Z23 A;  4C3B A;  1A7E A;  2J0X A;  2LD6 A;  4IB4 A;  3JSE O;  1RMV A;  4U5F E;  4P6I C;  4G7O F;  3AGT A;  4N4W A;  5B3S C;  1C17 M;  1TWH A;  1LVK A;  2KJG A;  4YL1 A;  3ITF A;  4BJ6 C;  2RD9 A;  1S7Z A;  3O39 A;  3QMK A;  2XXA B;  3NDB B;  1M57 C;  1SF8 A;  3RW0 A;  2LSE A;  3JT1 A;  2HS5 A;  1KTM A;  3NG1 A;  1LIH A;  1NBB A;  1T6Q A;  2P6V A;  3ABK C;  3TQO A;  4C7O B;  4OD4 A;  2B0H A;  3JYH A;  1FMV A;  4ANJ A;  2KSF A;  2A1D D;  1XZQ A;  2XL4 A;  3C63 A;  2WVN A;  2CDQ A;  3DM5 A;  3NRH A;  4W8K A;  3S27 A;  2YRF A;  3HNJ A;  3SP1 A;  1Z6A A;  3EZH A;  1M2V A;  4MTF A;  2D4U A;  4I1O B;  4D4X A;  1RJ9 B;  1J8M F;  3UMH A;  4CS9 A;  4NTF A;  4XPW A;  2HJ3 A;  4BPM A;  4FAP B;  2G3V A;  1DOV A;  1LI5 A;  2KGO A;  3DE8 A;  3I5P A;  4OIQ F;  2XM4 A;  4XWJ A;  2L81 A;  3V5X A;  1SZI A;  4RBN A;  1HW1 A;  1ORJ A;  1ZYR F;  3EH1 A;  4U9D A;  2QTV A;  4AK9 A;  5HSW A;  1MMN A;  3DAF A;  1GGQ A;  1ZW2 A;  3X2Q C;  1T01 A;  2KW3 C;  3MLG A;  1ORY A;  2PFD A;  2JX0 A;  2FFH A;  1ZHT A;  2EPL X;  1CPR A;  4H4K C;  1T6U A;  5E3C A;  2L6F A;  3DMD A;  3FAJ A;  4NC3 A;  3VRC A;  3VYW A;  2DB4 A;  2KK1 A;  1DOW A;  4IAO A;  1WN0 A;  4N06 A;  4FES A;  2L6G A;  2X0C A;  5BUO A;  3ZTM A;  2MWQ A;  4B6I A;  4CS7 A;  1M2O A;  4YT4 A;  2PX0 A;  2PP4 A;  2OCC C;  2QUP A;  4ZLC A;  4CSA C;  1D0Y A;  1U6H A;  4GQH A;  4YL0 A;  4CIP A;  1BZ4 A;  3N24 A;  3M4C A;  4W8P A;  2HMQ A;  5E2Q A;  3AJM A;  1KU2 A;  4U5C E;  1L3P A;  2QLA A;  1ZHX A;  3MYF A;  3ZG1 A;  2IXM A;  3QZC A;  4PJM A;  3TOL A;  2J7P D;  5T3T A;  2HV7 A;  4U5G A;  1FFH A;  2OEX A;  3EJN A;  1JPN A;  3ZQV A;  1V55 C;  3LNM B;  3V5Z A;  3FXH A;  2LCH A;  1AUE A;  4K0D A;  3DZA A;  2ZXO A;  4G78 A;  1TKN A;  2EPN A;  3QVY A;  1J8Y F;  2H7V C;  3CZ6 A;  3AG3 C;  3BRJ A;  2P0N A;  1WTY A;  1O5H A;  3QVZ A;  4IGG A;  5COF A;  4CDV A;  5JT4 A;  2R7S A;  2EIK C;  2H7B A;  2I15 A;  1MMG A;  3EZI A;  3LEO A;  1YZC A;  3U9M A;  1FTS A;  2NPU A;  4DOZ A;  1OCC C;  1NG1 A;  2YEV A;  4E7S A;  3H65 A;  2J9U A;  3Q6N A;  5CIV A;  4E17 A;  1TWG A;  4EUK B;  4DRJ B;  2C03 A;  4N6C A;  3JYY A;  3M79 A;  5JRA A;  3FOP A;  1H7I A;  1TWC A;  2P1A A;  2XSE A;  3M1C B;  1FMW A;  4MND A;  3UMI A;  5D91 A;  3PDM P;  3RKO F;  4G7Z F;  1SR2 A;  2Y69 C;  2Q9A A;  4MW3 A;  3Q7L A;  1UG7 A;  2YQY A;  1YZA A;  5JLI A;  1ZZP A;  2YLG A;  4F4B A;  2BL2 A;  4GEH A;  1LKX A;  2XM0 A;  4CJO A;  3CSK A;  4JVS A;  3EHM A;  1TWA A;  3B9Q A;  2B0J A;  4EBJ A;  5BQH A;  2EPK X;  3W8I A;  3ZVR A;  1JOG A;  1LS1 A;  1U89 A;  3KYI A;  4IJJ A;  1XZP A;  3EGD B;  4XPX A;  1A7V A;  2CW0 F;  1YA9 A;  1OW8 A;  2EIN C;  3U8P A;  1T5O A;  4DRH B;  2KYH A;  5KYX B;  2CGE A;  3ASO C;  3T6J A;  3GM2 A;  5F28 E;  4EKW A;  3RVZ A;  4CBE A;  3OEO A;  4EHP A;  1MMD A;  4LAC B;  1AEP A;  2M4E A;  3EFO A;  1GQA A;  1TFK B;  5EGY A;  1G4U S;  1T9K A;  2ZXR A;  2WL8 A;  2L6H A;  2YKZ A;  4DRI B;  1K40 A;  2R9R B;  2OJE D;  3LLI A;  4JKV A;  4WGZ A;  3S9O A;  3VF0 A;  4CDA A;  3ZIB A;  4RDA A;  1D1B A;  2IOQ A;  2YL0 A;  3TD7 A;  2R25 A;  3F47 A;  3G4Z A;  5FZT A;  3RYL A;  2XLO A;  2XLV A;  5COG A;  3T4R A;  1T6I A;  3W2W A;  1YAU O;  2NUP A;  1BBH A;  2HUJ A;  2F22 A;  1V54 C;  3EG9 B;  3ZDL A;  5DLJ A;  1Q0K A;  1Y4C A;  1RKE A;  1K04 A;  5AC4 A;  1A7D A;  3GEI A;  3ECS A;  3M4B A;  4ZLD A;  1M2V B;  3HNL A;  4XQ1 A;  2LFF A;  2L7A A;  4ULW A;  2PNO A;  2H7O A;  3MX3 A;  2ZXW C;  4JC7 A;  3G4X A;  5B1B C;  4C3D A;  3GOR A;  5DQT A;  1TR2 A;  4AX2 A;  3L34 A;  1JMW A;  1QKR A;  4YT5 A;  4LDK A;  3L0I A;  3NYM A;  2HFI A;  2C04 A;  2EIM C;  3GEH A;  3AG1 C;  1PCX A;  3K1I A;  1B68 A;  3S90 A;  2UUH A;  1QLE C;  3DJU B;  2HMZ A;  5A6J A;  2ASR A;  4P9T A;  4EBB A;  4BJ5 A;  1G5Z A;  1VMA A;  1G4W R;  2M64 A;  3EPV A;  2Y3B A;  2TMV P;  3KMI A;  3U0C A;  4BEJ A;  2QY9 A;  3FOO A;  4U5B E;  1ZHZ A;  1OKK A;  3IQ6 A;  1E2X A;  1Z7Q c;  4CS8 C;  3IQC A;  4X0R A;  4L6R A;  1QVX A;  1NFO A;  3NMI A;  4O7G A;  1APC A;  3KL4 A;  5L3Q A;  2AWC A;  3J06 A;  3GWL A;  2Q7R A;  4BG0 A;  5L0J A;  1ZVZ A;  4HFF B;  4AL1 A;  4LLC A;  4KC9 A;  1OXB A;  3LS0 A;  2Q00 A;  2Q4F A;  3FDQ A;  3S0X A;  3KPH A;  1BR2 A;  2HJM A;  1NZE A;  2IXO A;  4J32 B;  4Z9I A;  3W4Y A;  4XLP F;  3U5S A;  1E83 A;  3WG7 C;  4OIO F;  4JCH A;  4AL0 A;  3K66 A;  4PJN A;  5JVE A;  2LQG A;  2P61 A;  4PAC A;  2Y3D A;  1JR8 A;  1MMA A;  3LLK A;  5F5H A;  2PF4 E;  4LDQ A;  3UGO A;  1EKY A;  1HMO A;  1S05 A;  2OU6 A;  2YWA A;  3FHD A;  2BC5 A;  4YN0 B;  1VYK A;  2XLW A;  4MQ9 F;  2ICW G;  3T6B A;  4EWC A;  2L9J A;  4I3M A;  4CDY A;  1IZM A;  1BDJ B;  1Q0F A;  3ATP A;  3JRT A;  1V4A A;  3K33 A;  2HZ8 A;  4JRZ A;  4ULV A;  2R03 A;  4WAB A;  2J8W A;  5A6B A;  3JRM O;  5T1D B;  2VB6 A;  3S28 A;  2EIL C;  2KNH A;  1TQG A;  3ZWI A;  3AQB A;  4DXW A;  4MW8 A;  5EHH A;  3LAY A;  1MQV A;  1MNE A;  2CNW A;  3UGP A;  2KC3 A;  1NU9 C;  2YVK A;  4DVY P;  3TK0 A;  4MVM A;  5AGF A;  3NMK A;  1XWJ A;  3ABL C;  4RD9 A;  1ST6 A;  2J9B A;  5BQI A;  3WHN A;  2VCB A;  3AOU A;  3QTH A;  5COM A;  5A6B D;  2HKV A;  3CEX A;  1D0X A;  1MND A;  2IYL D;  2XS1 A;  4IWB A;  4Q7C A;  5B3I A;  2OJQ A;  4OIN F;  2CNW D;  4EIY A;  3C7J A;  3S29 A;  1WGW A;  4BJ6 A;  256B A;  2HSB A;  2OG2 A;  3TJ5 A;  4BEM J;  3T6G B;  5A69 A;  4U5D E;  4PR9 A;  2GFH A;  1HY5 A;  1R5I D;  2NSF A;  3V7O A;  2AWY A;  1YYJ A;  2V26 A;  1OXK A;  3EH2 A;  3TOM A;  2G62 A;  2DYS C;  2W9Y A;  3RQF A;  1ZU5 A;  1K05 A;  3SXK A;  3VAY A;  4CJG A;  1F1M A;  1NU7 D;  1RCP A;  2YLD A;  3ZSU A;  4O6Y A;  2LFD A;  4Q4Z F;  3DD7 A;  1CGN A;  4CX9 A;  4EBK A;  3NKD A;  3EFO B;  4OIP F;  1G8X A;  4KBL A;  3IQT A;  3L8I A;  2H8A A;  4HE8 D;  2R7Q A;  3RF3 A;  2CCY A;  3B0V C;  5KYW A;  2V3C C;  1QQ3 A;  3HNI A;  3KKB A;  4Z9H A;  3R2P A;  3V5Y A;  2XLD A;  3S84 A;  3ASN C;  4YWQ A;  2EIJ C;  1L7C A;  2R05 A;  4G0H A;  4JZA A;  2I8B A;  5D92 A;  3SXM A;  5IY5 C;  1R4T A;  3DM9 B;  3GAN A;  5BQG A;  3PHF 2;  3K1I C;  1FR0 A;  4K7B A;  1JAF A;  2XLM A;  3LEV A;  3AG4 C;  4OD5 A;  2D5R B;  1BR1 A;  1RKE B;  3HLZ A;  4NTA A;  2YL3 A;  5CI8 A;  3RQE A;  2XL6 A;  5A6A A;  1E84 A;  2WVQ A;  1CGM E;  3AGU A;  3HJC A;  1Q0D A;  2JPU A;  3MBG A;  5KYN A;  3ZQY A;  1GM5 A;  3Q6M A;  1E86 A;  4AE4 A;  3FMS A;  2GA0 A;  1RKC A;  1OR3 A;  4G7H F;  5KYY A;  5TJ5 E;  4MS2 A;  1CPQ A;  1SMY F;  2GDC A;  3EGX A;  3K1H A;  4YK5 A;  4BJ1 A;  4CS9 C;  1OQC A;  2NSG A;  5L0D A;  5L0G A;  4UDV A;  3IEE A;  4JW1 A;  5T3W A;  1NSG B;  1C03 A;  2IXN A;  1OR2 A;  3US6 A;  2JD3 A;  1D0Z A;  1M6T A;  2J9W A;  1M56 C;  2Q3T A;  4I44 A;  4MVQ A;  2P7V A;  5KYU A;  2W4B A;  4J7T A;  1FFT C;  2OOC A;  2WB7 A;  3HKK A;  3R7C A;  3VM6 A;  5L0H A;  4U9E A;  2A6H F;  4LDR A;  4O6M A;  2WZL A;  2ZPA A;  1H9T A;  2VC9 A;  4IRU A;  3SYN A;  4JE9 A;  2G3K A;  5JP7 A;  2CYD A;  2DI3 A;  1YDI A;  3POV A;  2YZS A;  3DAG A;  2R7X A;  2HV6 A;  1JRA A;  3DE9 A;  3FVY A;  5E3A A;  3NMJ A;  3EQL F;  2OEV A;  4R32 A;  3KH2 A;  2DGJ A;  3ABM C;  1OCO C;  2FAP B;  1Z3I X;  3OA1 A;  1GS9 A;  1PD0 A;  1H9G A;  3ZC4 A;  3SEO A;  4MTG A;  2E87 A;  3DWW A;  1LE4 A;  2WVO A;  3TUL A;  5FCL A;  3O10 A;  4PK4 A;  5GPG B;  3RIP A;  4JTC B;  4Q5S F;  5KYX A;  2O9X A;  2Z15 A;  5EK0 A;  1I4Z A;  4E0H A;  4NY3 A;  3LS1 A;  5CI9 A;  4PFP A;  2OKU A;  4E7Z A;  3AG2 C;  3KYJ A;  3M15 A;  1OW7 A;  5HV9 A;  2IXP A;  5F5F A;  2R02 A;  1VLS A;  5L0C A;  1VB5 A;  2NG1 A;  3U3F A;  4LLE A;  1IW7 F;  4MVS A;  3DXJ F;  4C3E A;  3UR3 C;  4DBQ A;  3CQZ A;  3JCU Q;  3BEH A;  2R7V A;  4PJJ A;  1LI7 A;  1OKK D;  3C8G A;  4HEA J;  3RVY A;  3W8H A;  1LE2 A;  1OW6 A;  4JJF A;  2KQ9 A;  3PMR A;  1O87 A;  2MYS A;  4JUR I;  3JZ0 A;  3B71 A;  3EG9 A;  1OCR C;  4I1M A;  3C62 A;  2LK4 A;  1YJG A;  4LER A;  4O79 A;  4NQF A;  4XTK A;  3C18 A;  3LNR A;  3W2V A;  2NUT A;  2R7R A; 
#chains in the Genus database with same CATH homology
 4NTB A;  4JCZ A;  4J7T A;  3HKK A;  5BQH A;  3LEO A;  3PCV A;  2Q7R A;  5HV9 A;  4J7Y A;  4JRZ A;  4WAB A;  4AL1 A;  4NTF A;  4NTA A;  4BPM A;  2PNO A;  4JC7 A;  4YL3 A;  4YL0 A;  4YL1 A;  4AL0 A;  2H8A A;  4YK5 A;  2UUH A;  2UUI A;  5BQI A;  3B29 A;  3DWW A;  5BQG A;  5K0I A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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