4DRIB

Co-crystal structure of the ppiase domain of fkbp51, rapamycin and the frb fragment of mtor
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
96
structure length
96
Chain Sequence
GAMDPEFMEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRIS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin.
pubmed doi rcsb
molecule tags Isomerase/transferase
source organism Homo sapiens
molecule keywords Peptidyl-prolyl cis-trans isomerase FKBP5
total genus 38
structure length 96
sequence length 96
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2012-02-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.150 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) FKBP12-rapamycin binding domain 4driB00
1AUEA 1NSGB 4DRHB 4DRIB 5GPGB 2FAPB 4DRJB 2RSEB 4FAPB 3FAPB 1FAPB 2NPUA 2GAQA
chains in the Genus database with same CATH superfamily
4KNVA 4XLPF 3EJNA 3Q6MA 2DI3A 2MYSA 3PMRA 4G0HA 2Q3TA 3EGXB 2OQMA 4YL3A 1SYQA 2AWCA 4YL1A 3MYIA 3H65A 3G50A 3HNLA 3Q7LA 1T9KA 3K33A 2CGEA 3R2PA 3U5SA 4E0HA 4HE8D 5AC4A 1TKNA 1D0YA 4CIPA 3GANA 4MVMA 2P7VA 1YJGA 3DE9A 1OW7A 4J30B 2QY9A 4NTAA 4CSAA 2XRHA 4NC3A 3ZIBA 4AE4A 4E7SA 3PCVA 5AGFA 2CCYA 2Q9BA 2YKZA 3ZTMA 5A69A 1DOWA 2WVNA 2XM4A 5JVEA 4O79A 4C7OB 1T6UA 4U9EA 1TFKB 4YL0A 5L0HA 3C8GA 2IYLD 1PV3A 1F1MA 1WTYA 3SYNA 4CJGA 4KI2A 1EA8A 2A6HF 3B9QA 3DD7A 3RW0A 1HW1A 3FXHA 5KYUA 4JRZA 4AL0A 1YA7O 2CDQA 1AUEA 4NTBA 1BZ4A 4PFOA 2KQ9A 1O3UA 2KNHA 4LDQA 1OCRC 3T4RA 2AU5A 4Q5SF 3WODF 1NFOA 1FFTC 2CW0F 4CDYA 2J7PD 1FAPB 2YVKA 2NPUA 3SXZA 1E85A 4DRHB 1NU9C 3HKKA 4OIRF 3FAJA 1HY5A 2Q9AA 1OR2A 3NYLA 3NYMA 2E87A 3EH2A 3AJMA 5A6JA 4BEJA 2XLWA 4IB4A 4EKWA 2WVOA 3F47A 4XPYA 1LI5A 3S0XA 2ICWG 2YLGA 4YT5A 3GEIA 1TWHA 3GWNA 3IQ6A 5JSLA 4IJJA 2PX3A 2KGOA 4JKVA 2R02A 4EBKA 1E83A 1O87A 3EZIA 4JTDB 1XZPA 2KW3C 2EIKC 4CDVA 2X0CA 3RH3A 3QW0A 3UR3C 3EPVA 3GM1A 2XL8A 4U5EE 3LJBA 4PK4A 2D5RB 1WWPA 2L6HA 2M4EA 3EHNA 3JTLO 2Q00A 4K1OA 4DXWA 2YRFA 3EG9B 4Z9IA 2WZLA 3NKEA 1SR2A 3LUTB 4EIYA 3LNRA 3O6XA 3LS1A 2A69F 1Q0GA 2VCBA 5JLIA 5EGYA 4MTFA 2A0UA 1ZW3A 2P0NA 3L8IA 1HMOA 2G62A 3DAGA 2XLOA 4PR9A 2OU6A 3U8PA 1Z3IX 1ZHYA 3JRTA 4BPMA 4EUKB 1LPEA 2Y3GA 2QNLA 4AK9A 2LFFA 3M79A 1JPNA 4N6CA 4JTCB 4AE4B 3DKAA 4G7HF 2OCCC 3ABLC 4RDAA 3U3FA 1D0XA 3QZCA 4CS8C 3U2LA 5A6BA 4O6YA 2C03A 1RJ9A 2VASA 1L7CA 3EFOA 3L1MA 1U89A 1BR4A 2G3VA 3C8GB 3K1IC 1FNTc 3AG3C 1M6TA 3JYHA 3RVZA 3GORA 3DE8A 1TR2A 2J0XA 1CGNA 3JSZA 2R05A 3MBGA 5KYUB 2CYDA 2FFHA 1KTMA 3AG2C 4MVRA 3JCUQ 4LERA 1Z7Qc 1RKEA 1HE9A 2ZXPA 3NDBB 2AVKA 1NSGB 2PP4A 4JVSA 1A7EA 4DRIB 1W2WA 3H2UA 3LEVA 3W2WA 1Q0DA 4G78A 3HJCA 5A6AA 4E7ZA 1K40A 2NUPA 2P1AA 1OXBA 3ITFA 4IAOA 4MVUA 3BEHA 2WL8A 3O10A 1AVOB 1E2XA 3CSKA 1V4AA 4R32A 5GPGB 5KYYB 2NG1A 1OCCC 4KNWA 1MMGA 2L6FA 4IWBA 1V55C 2YL7A 3ECSA 5KYXA 1V74B 1GGQA 1JR8A 4AX2A 1C17M 3TULA 1V54C 2IXPA 1T6IA 5CI9A 3M15A 1A0BA 3V5XA 2UUIA 4DVYP 1ZHWA 3EGDA 1VMAA 2UUHA 1J8YF 5KYYA 2I8BA 1D0ZA 3FOOA 1M2VA 3ABMC 3GEHA 4IRUA 4NCQA 4PJMA 3ZTZA 4F4BA 1RXQA 1WATA 2AWYA 2XXAA 4CJOA 3RFYA 2XL4A 3G4XA 3QTHA 4UDVA 3VYWA 2P61A 3LEOA 1PD1A 3O39A 1PCXA 1TWCA 2NUTB 4PACA 1K05A 1FMVA 2LCHA 2OG2A 1TWAA 3C18A 2H7BA 3I4UA 1H7IA 1T6QA 3C8ZA 1NU7D 2GAQA 4Q7CA 1Y4CA 5COMA 3TJ6A 5BQIA 2R7SA 1IZMA 4J7YA 2ZXWC 3ZVRA 2J9VA 4Z9JA 3UMKA 4OIOF 4JC7A 5JP7A 2EPOA 3S90A 4XQ1A 3FOPA 1RJ9B 2OOCA 4RBNA 3EFOB 2VCCA 2IM8A 4J32B 5E3AA 4MW8A 3RYLA 1FR0A 1JAFA 3ZWIA 1OCZC 4IAQA 1ZHXA 2HSQA 1C03A 2ETSA 3IEEA 4GYTA 2D4UA 4YJWA 2Q9CA 4O6MA 1CGME 2LSEA 3DM9B 5JRAA 4NQFA 2RSEB 2DGJA 3UGOA 5DS4A 2YL0A 2W4MA 3GM2A 5HV9A 1CGOA 4GEHA 3ZQYA 2XLHA 1U0BB 4CSAC 4JE9A 4XEKA 2DYSC 2NUPB 4LLEA 1I5NA 2ZXRA 1M2OA 3B29A 3DZAA 4IGGA 3C62A 1HE1A 2Y3DA 3UNGC 3W2VA 2IXOA 1UG7A 4G7ZF 2J7PA 3QW1A 4OD4A 3S27A 4DJ9A 1TQGA 2A1DD 4P9FA 5KYXB 2OEXA 5B1BC 1Q0MA 5E3CA 1VLSA 3ZG1A 1KNYA 4WJ0A 3MLGA 2TMVP 3EGDB 3DAFA 1M2VB 3UMIA 2J9WA 4JZAA 1L3PA 1I4ZA 1OR3A 2A0BA 3AGUA 2XXAB 1D1CA 1LS1A 4CS9A 2FAPB 4YT2A 3N24A 1XZQA 2C04A 3DM5A 5CIVA 3VF0A 4D4XA 5L0FA 3U9JA 2VB6A 2HV7A 3QVYA 4JIOA 4P9TA 1QVXA 2W45A 2YEVA 4B6IA 5AC5A 3JZ0A 2Y69C 3HLZA 4OIQF 2VH3A 4JEBA 2ZXOA 1CPQA 3HNIA 1OCOC 1QSPA 1Y6DA 2OJED 3TOLA 3A9CA 3AG4C 5E33A 5T3WA 5TJ5E 3U0CA 1HMDA 3BRJA 4NTFA 4ULVA 3U9MA 1LIHA 2XLEA 3H2VA 4IARA 3DMDA 1NG1A 1QQ3A 2IXNA 4I44A 3ZDLA 2BL2A 3EH1A 3VAYA 1GQAA 3W4YA 3VM6A 4XTKA 5L0IA 2M64A 2EPMX 2YHSA 3NRHA 2Q4FA 1WOLA 2HS5A 2LD6A 2XSEA 2L7AA 3S29A 2HV6A 3AQBA 3L8JA 4XLNF 1R5ID 3CQZA 3L34A 1TFOB 4E18A 1UFBA 4QDLA 3TQOA 1MNEA 1YA9A 3S28A 3DI5A 4E0IA 3S84A 3T9OA 1CPRA 1D1BA 1YLMA 3HNJA 4OD5A 5BQHA 2L6GA 1Z63A 3ZSUA 3N0TA 1Q0FA 2R25A 4BJ5A 4NY3A 3OEOA 4DBQA 2PBEA 1MMDA 4FX5A 3EHMA 2EPNA 1VYIA 2NSFA 1T01A 2R7OA 2ASRA 2YL3A 3HTKC 3Q6NA 3CEXA 2XS8A 4ANJA 5L0GA 4LDKA 2IBFA 3US6A 3LS0A 3AG1C 4JJGA 1DOVA 2BE5F 1R4TA 2P6VA 2V26A 2W9YA 4MTOA 3L0IA 5E2QA 3V5YA 4A2NB 1B68A 1C02A 4N4WA 5EHHA 1E84A 3SZRA 1QKRA 4C3BA 2FGYA 4BJ6A 3A11A 1ORSC 1ST6A 1OKKD 1QPUA 1ZVZA 1ZZPA 4LLCA 5T1DB 3DJNB 4U5FE 2RD9A 3C63A 5FCLA 3FDQA 1ZHTA 1LM3B 2PFDA 4PJJA 4ER9A 3VRCA 4I1MA 3GEEA 3RF3A 3AOUA 4BJ1A 1G8XA 1A7VA 1ORJA 1D1AA 3RQGA 3MX3A 3SNHA 5JS5A 3E70C 1LS4A 4FESA 4JEAA 4QI2A 3G4ZA 1I4YA 2R7UA 1NZEA 4CIHA 4WABA 3OWTA 4MS2A 2J46A 2KJGA 2QTVA 2R7TA 1VYKA 2H7VC 1YYXA 4HFFB 5B1AC 1ORYA 2R7RA 2IXMA 4P6IC 3E9VA 3KL4A 3K66A 4WGZA 2HMZA 2YZSA 4ULWA 1YZCA 1ZU4A 3QVZA 4EHPA 4W8KA 1A41A 2G3KA 2MHRA 3LAYA 1EKYA 3M1CB 3Q7GA 3X2QC 2R03A 1MQVA 4O6NA 1RMVA 2QLAA 2ZPAA 1H6GA 5IY5C 3IPMO 2Y3BA 2Z15A 1OW8A 1OQCA 3KPHA 1AEPA 3FAPB 4U9DA 3DXJF 3JRMO 4MVSA 3J06A 3O55A 2A6EF 1LE2A 2CNWA 1BR2A 4L6RA 1ZHZA 1GM5A 2V3CC 3RVYA 3GM3A 5D92A 4YWQA 2KSFA 4MVOA 5KYNA 2R7WA 4RD9A 3X1OA 3U3BA 3JT1A 3ASOC 1J8MF 1LE4A 4I3MA 3LESA 4JCZA 3B0UX 1YYJA 5F28E 1VLTA 3LNMB 3FHDA 1RKEB 1VOMA 2A68F 2KYHA 4U5HA 5DVWA 1KU2A 3NKDA 4ZLDA 2CNWD 1H9TA 3N2ZB 4ONSA 5DQTA 4MQ9F 5L3QA 5HSWA 3RQFA 5EK0A 1BBHA 1QLEC 2IOQA 4EWCA 1SZIA 1U6HA 3DWWA 1NBBA 4H4KC 4JW1A 3MFNA 3TD7A 2HJMA 1FFHA 3PHF2 2HFIA 3QMKA 2LK4A 2EIMC 2HKVA 4HFKB 2YLDA 3EG9A 5A6KA 3ATPA 5D91A 1A7DA 3U2MA 3B71A 3IQTA 2YWAA 4MVZA 1APCA 3SXYA 3RIPA 1OW6A 1IW7F 4JCHA 5DLJA 5B3IA 1YVIA 3IQCA 2L9JA 4CS7A 3WAQA 3I5QA 1LVKA 1MMNA 4CS9C 2J0WA 2AP3A 2LIGA 3R7CA 4H54A 2LP4A 4G7OF 1Z5ZA 3RKOF 4AL1A 1VTMP 4PFPA 4OINF 5KYWA 1RKCA 1ZW2A 1G5ZA 2KK1A 3TOMA 1NFNA 1WN0A 2XM0A 256BA 3M4BA 4DVZA 3U8VA 3EQLF 2PF4E 2J8WA 5L0JA 1JRAA 3TJ5A 4C3DA 4D4NA 2B0JA 2HZ8A 2WZGA 3B0PA 2J9UA 1LKXA 3GODA 2QUPA 2GA0A 2WVQA 3B0VC 2PX0A 3DJUB 3F46A 3NMIA 1E86A 2OKUA 4XEVA 3K7DA 5DS5A 5L0CA 2MWQA 4FAPB 2YQYA 2VCAA 4YK5A 1Z6AA 3RQEA 3KYJA 2H8AA 2JPUA 2LQGA 4K0DA 3KMIA 4MVQA 3C7JA 4K7BA 3KKBA 3KYIA 3UGPA 2ZD9A 3T6GB 2DYRC 4W8PA 3C8GD 3ABKC 1O5HA 5DQZA 2KC3A 3IHUA 2I15A 3S9OA 3I5PA 2J9BA 1YAUO 2R7QA 5T3TA 1ZU5A 4ZLCA 3W8HA 4BJ5C 1WGWA 1VK5A 2EINC 1H9GA 5COFA 2PNOA 4BEMJ 5L0DA 3T6JA 4C3EA 2R7XA 3PDMP 1OKKA 2NSGA 4JJFA 2VC9A 4PJNA 2HUJA 3NMJA 2XLDA 3AGTA 4XPWA 2QE9A 4KC9A 5JUAA 2O9XA 3SEOA 2GFHA 4X0RA 2Q7RA 3V7OA 4CDAA 4LDRA 5F5FA 3K1HA 4MNDA 3ASNC 4MTGA 1Q0KA 4BJ6C 1QZXA 2B0HA 4DBRA 4OIPF 2JD3A 1YARO 4KBLA 2NUTA 4CX9A 3W8IA 3FMSA 2Y39A 5BUOA 2GWWA 2XLMA 5KYWB 3GWLA 2F22A 1MNDA 1WASA 4N06A 4DOZA 3JYYA 5COGA 2JX0A 3NMKA 4O7GA 4E17A 3ZC4A 4LACB 1GS9A 2HJ3A 4DRJB 1G4US 2R9RB 3LLKA 4CS8A 5B3SC 5DS6A 1BDJB 5L3VA 3CAXA 3AQCA 2J45A 3K1IA 1TWGA 4I1OB 1Z23A 3EGXA 2WZFA 1JMWA 1RCPA 1EQ1A 2LFDA 4EBJA 4MW3A 3SXKA 2EPKX 3IQ5A 1PD0A 3KH2A 1EI7A 4M63A 3LLIA 3NG1A 1VB5A 5FZTA 4EBBA 3SXMA 1MMAA 3WG7C 2EIJC 2EPLX 5CI8A 2YL1A 4Z9HA 4A4AA 3EZHA 3OA1A 1FMWA 4YT4A 5A6BD 5F5HA 2WB7A 3FVYA 1M57C 4U5BE 4FWVA 1FTSA 1HW2A 2YLIA 3NYJA 2H7OA 3UMHA 3M4CA 4U5CE 5K0IA 2R7VA 3JSEO 1S05A 4C7OA 3CZ6A 2Y3HA 1JPJA 2XL6A 3K6BA 5JT4A 1K04A 2L81A 3HNKA 4GQHA 4JURI 4XEFA 3POVA 1T5OA 1LI7A 4J7TA 4YN0B 3WHNA 3ZQVA 4HEAJ 2XLVA 2XS1A 1G4WR 1SF8A 4QI0A 4WGYA 3T6BA 1BR1A 2GDCA 1JOGA 4XWJA 1N1CA 5BQGA 1YDIA 2X51A 3MYFA 4Q4ZF 2BC5A 4XPXA 1OXKA 2W4BA 2OJQA 3V5ZA 4PJLA 1SMYF 1ZYRF 1NLXA 4BG0A 1S7ZA 2EILC 4N6HA 4U5DE 3TK0A 2OEVA 4BJTA 4YT8A 1XWJA 2HMQA 1YZAA 2DB4A 1M56C 4CBEA 4U5GA 3SP1A 4JTAB 2HSBA
chains in the Genus database with same CATH topology
1AUEA 1NSGB 4DRHB 4DRIB 5GPGB 2FAPB 4DRJB 2RSEB 4FAPB 3FAPB 1FAPB 2NPUA 2GAQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AUE A;  1NSG B;  4DRH B;  4DRI B;  5GPG B;  2FAP B;  4DRJ B;  2RSE B;  4FAP B;  3FAP B;  1FAP B;  2NPU A;  2GAQ A; 
#chains in the Genus database with same CATH topology
 4KNV A;  4XLP F;  3EJN A;  3Q6M A;  2DI3 A;  2MYS A;  3PMR A;  4G0H A;  2Q3T A;  3EGX B;  2OQM A;  4YL3 A;  1SYQ A;  2AWC A;  4YL1 A;  3MYI A;  3H65 A;  3G50 A;  3HNL A;  3Q7L A;  1T9K A;  3K33 A;  2CGE A;  3R2P A;  3U5S A;  4E0H A;  4HE8 D;  5AC4 A;  1TKN A;  1D0Y A;  4CIP A;  3GAN A;  4MVM A;  2P7V A;  1YJG A;  3DE9 A;  1OW7 A;  4J30 B;  2QY9 A;  4NTA A;  4CSA A;  2XRH A;  4NC3 A;  3ZIB A;  4AE4 A;  4E7S A;  3PCV A;  5AGF A;  2CCY A;  2Q9B A;  2YKZ A;  3ZTM A;  5A69 A;  1DOW A;  2WVN A;  2XM4 A;  5JVE A;  4O79 A;  4C7O B;  1T6U A;  4U9E A;  1TFK B;  4YL0 A;  5L0H A;  3C8G A;  2IYL D;  1PV3 A;  1F1M A;  1WTY A;  3SYN A;  4CJG A;  4KI2 A;  1EA8 A;  2A6H F;  3B9Q A;  3DD7 A;  3RW0 A;  1HW1 A;  3FXH A;  5KYU A;  4JRZ A;  4AL0 A;  1YA7 O;  2CDQ A;  1AUE A;  4NTB A;  1BZ4 A;  4PFO A;  2KQ9 A;  1O3U A;  2KNH A;  4LDQ A;  1OCR C;  3T4R A;  2AU5 A;  4Q5S F;  3WOD F;  1NFO A;  1FFT C;  2CW0 F;  4CDY A;  2J7P D;  1FAP B;  2YVK A;  2NPU A;  3SXZ A;  1E85 A;  4DRH B;  1NU9 C;  3HKK A;  4OIR F;  3FAJ A;  1HY5 A;  2Q9A A;  1OR2 A;  3NYL A;  3NYM A;  2E87 A;  3EH2 A;  3AJM A;  5A6J A;  4BEJ A;  2XLW A;  4IB4 A;  4EKW A;  2WVO A;  3F47 A;  4XPY A;  1LI5 A;  3S0X A;  2ICW G;  2YLG A;  4YT5 A;  3GEI A;  1TWH A;  3GWN A;  3IQ6 A;  5JSL A;  4IJJ A;  2PX3 A;  2KGO A;  4JKV A;  2R02 A;  4EBK A;  1E83 A;  1O87 A;  3EZI A;  4JTD B;  1XZP A;  2KW3 C;  2EIK C;  4CDV A;  2X0C A;  3RH3 A;  3QW0 A;  3UR3 C;  3EPV A;  3GM1 A;  2XL8 A;  4U5E E;  3LJB A;  4PK4 A;  2D5R B;  1WWP A;  2L6H A;  2M4E A;  3EHN A;  3JTL O;  2Q00 A;  4K1O A;  4DXW A;  2YRF A;  3EG9 B;  4Z9I A;  2WZL A;  3NKE A;  1SR2 A;  3LUT B;  4EIY A;  3LNR A;  3O6X A;  3LS1 A;  2A69 F;  1Q0G A;  2VCB A;  5JLI A;  5EGY A;  4MTF A;  2A0U A;  1ZW3 A;  2P0N A;  3L8I A;  1HMO A;  2G62 A;  3DAG A;  2XLO A;  4PR9 A;  2OU6 A;  3U8P A;  1Z3I X;  1ZHY A;  3JRT A;  4BPM A;  4EUK B;  1LPE A;  2Y3G A;  2QNL A;  4AK9 A;  2LFF A;  3M79 A;  1JPN A;  4N6C A;  4JTC B;  4AE4 B;  3DKA A;  4G7H F;  2OCC C;  3ABL C;  4RDA A;  3U3F A;  1D0X A;  3QZC A;  4CS8 C;  3U2L A;  5A6B A;  4O6Y A;  2C03 A;  1RJ9 A;  2VAS A;  1L7C A;  3EFO A;  3L1M A;  1U89 A;  1BR4 A;  2G3V A;  3C8G B;  3K1I C;  1FNT c;  3AG3 C;  1M6T A;  3JYH A;  3RVZ A;  3GOR A;  3DE8 A;  1TR2 A;  2J0X A;  1CGN A;  3JSZ A;  2R05 A;  3MBG A;  5KYU B;  2CYD A;  2FFH A;  1KTM A;  3AG2 C;  4MVR A;  3JCU Q;  4LER A;  1Z7Q c;  1RKE A;  1HE9 A;  2ZXP A;  3NDB B;  2AVK A;  1NSG B;  2PP4 A;  4JVS A;  1A7E A;  4DRI B;  1W2W A;  3H2U A;  3LEV A;  3W2W A;  1Q0D A;  4G78 A;  3HJC A;  5A6A A;  4E7Z A;  1K40 A;  2NUP A;  2P1A A;  1OXB A;  3ITF A;  4IAO A;  4MVU A;  3BEH A;  2WL8 A;  3O10 A;  1AVO B;  1E2X A;  3CSK A;  1V4A A;  4R32 A;  5GPG B;  5KYY B;  2NG1 A;  1OCC C;  4KNW A;  1MMG A;  2L6F A;  4IWB A;  1V55 C;  2YL7 A;  3ECS A;  5KYX A;  1V74 B;  1GGQ A;  1JR8 A;  4AX2 A;  1C17 M;  3TUL A;  1V54 C;  2IXP A;  1T6I A;  5CI9 A;  3M15 A;  1A0B A;  3V5X A;  2UUI A;  4DVY P;  1ZHW A;  3EGD A;  1VMA A;  2UUH A;  1J8Y F;  5KYY A;  2I8B A;  1D0Z A;  3FOO A;  1M2V A;  3ABM C;  3GEH A;  4IRU A;  4NCQ A;  4PJM A;  3ZTZ A;  4F4B A;  1RXQ A;  1WAT A;  2AWY A;  2XXA A;  4CJO A;  3RFY A;  2XL4 A;  3G4X A;  3QTH A;  4UDV A;  3VYW A;  2P61 A;  3LEO A;  1PD1 A;  3O39 A;  1PCX A;  1TWC A;  2NUT B;  4PAC A;  1K05 A;  1FMV A;  2LCH A;  2OG2 A;  1TWA A;  3C18 A;  2H7B A;  3I4U A;  1H7I A;  1T6Q A;  3C8Z A;  1NU7 D;  2GAQ A;  4Q7C A;  1Y4C A;  5COM A;  3TJ6 A;  5BQI A;  2R7S A;  1IZM A;  4J7Y A;  2ZXW C;  3ZVR A;  2J9V A;  4Z9J A;  3UMK A;  4OIO F;  4JC7 A;  5JP7 A;  2EPO A;  3S90 A;  4XQ1 A;  3FOP A;  1RJ9 B;  2OOC A;  4RBN A;  3EFO B;  2VCC A;  2IM8 A;  4J32 B;  5E3A A;  4MW8 A;  3RYL A;  1FR0 A;  1JAF A;  3ZWI A;  1OCZ C;  4IAQ A;  1ZHX A;  2HSQ A;  1C03 A;  2ETS A;  3IEE A;  4GYT A;  2D4U A;  4YJW A;  2Q9C A;  4O6M A;  1CGM E;  2LSE A;  3DM9 B;  5JRA A;  4NQF A;  2RSE B;  2DGJ A;  3UGO A;  5DS4 A;  2YL0 A;  2W4M A;  3GM2 A;  5HV9 A;  1CGO A;  4GEH A;  3ZQY A;  2XLH A;  1U0B B;  4CSA C;  4JE9 A;  4XEK A;  2DYS C;  2NUP B;  4LLE A;  1I5N A;  2ZXR A;  1M2O A;  3B29 A;  3DZA A;  4IGG A;  3C62 A;  1HE1 A;  2Y3D A;  3UNG C;  3W2V A;  2IXO A;  1UG7 A;  4G7Z F;  2J7P A;  3QW1 A;  4OD4 A;  3S27 A;  4DJ9 A;  1TQG A;  2A1D D;  4P9F A;  5KYX B;  2OEX A;  5B1B C;  1Q0M A;  5E3C A;  1VLS A;  3ZG1 A;  1KNY A;  4WJ0 A;  3MLG A;  2TMV P;  3EGD B;  3DAF A;  1M2V B;  3UMI A;  2J9W A;  4JZA A;  1L3P A;  1I4Z A;  1OR3 A;  2A0B A;  3AGU A;  2XXA B;  1D1C A;  1LS1 A;  4CS9 A;  2FAP B;  4YT2 A;  3N24 A;  1XZQ A;  2C04 A;  3DM5 A;  5CIV A;  3VF0 A;  4D4X A;  5L0F A;  3U9J A;  2VB6 A;  2HV7 A;  3QVY A;  4JIO A;  4P9T A;  1QVX A;  2W45 A;  2YEV A;  4B6I A;  5AC5 A;  3JZ0 A;  2Y69 C;  3HLZ A;  4OIQ F;  2VH3 A;  4JEB A;  2ZXO A;  1CPQ A;  3HNI A;  1OCO C;  1QSP A;  1Y6D A;  2OJE D;  3TOL A;  3A9C A;  3AG4 C;  5E33 A;  5T3W A;  5TJ5 E;  3U0C A;  1HMD A;  3BRJ A;  4NTF A;  4ULV A;  3U9M A;  1LIH A;  2XLE A;  3H2V A;  4IAR A;  3DMD A;  1NG1 A;  1QQ3 A;  2IXN A;  4I44 A;  3ZDL A;  2BL2 A;  3EH1 A;  3VAY A;  1GQA A;  3W4Y A;  3VM6 A;  4XTK A;  5L0I A;  2M64 A;  2EPM X;  2YHS A;  3NRH A;  2Q4F A;  1WOL A;  2HS5 A;  2LD6 A;  2XSE A;  2L7A A;  3S29 A;  2HV6 A;  3AQB A;  3L8J A;  4XLN F;  1R5I D;  3CQZ A;  3L34 A;  1TFO B;  4E18 A;  1UFB A;  4QDL A;  3TQO A;  1MNE A;  1YA9 A;  3S28 A;  3DI5 A;  4E0I A;  3S84 A;  3T9O A;  1CPR A;  1D1B A;  1YLM A;  3HNJ A;  4OD5 A;  5BQH A;  2L6G A;  1Z63 A;  3ZSU A;  3N0T A;  1Q0F A;  2R25 A;  4BJ5 A;  4NY3 A;  3OEO A;  4DBQ A;  2PBE A;  1MMD A;  4FX5 A;  3EHM A;  2EPN A;  1VYI A;  2NSF A;  1T01 A;  2R7O A;  2ASR A;  2YL3 A;  3HTK C;  3Q6N A;  3CEX A;  2XS8 A;  4ANJ A;  5L0G A;  4LDK A;  2IBF A;  3US6 A;  3LS0 A;  3AG1 C;  4JJG A;  1DOV A;  2BE5 F;  1R4T A;  2P6V A;  2V26 A;  2W9Y A;  4MTO A;  3L0I A;  5E2Q A;  3V5Y A;  4A2N B;  1B68 A;  1C02 A;  4N4W A;  5EHH A;  1E84 A;  3SZR A;  1QKR A;  4C3B A;  2FGY A;  4BJ6 A;  3A11 A;  1ORS C;  1ST6 A;  1OKK D;  1QPU A;  1ZVZ A;  1ZZP A;  4LLC A;  5T1D B;  3DJN B;  4U5F E;  2RD9 A;  3C63 A;  5FCL A;  3FDQ A;  1ZHT A;  1LM3 B;  2PFD A;  4PJJ A;  4ER9 A;  3VRC A;  4I1M A;  3GEE A;  3RF3 A;  3AOU A;  4BJ1 A;  1G8X A;  1A7V A;  1ORJ A;  1D1A A;  3RQG A;  3MX3 A;  3SNH A;  5JS5 A;  3E70 C;  1LS4 A;  4FES A;  4JEA A;  4QI2 A;  3G4Z A;  1I4Y A;  2R7U A;  1NZE A;  4CIH A;  4WAB A;  3OWT A;  4MS2 A;  2J46 A;  2KJG A;  2QTV A;  2R7T A;  1VYK A;  2H7V C;  1YYX A;  4HFF B;  5B1A C;  1ORY A;  2R7R A;  2IXM A;  4P6I C;  3E9V A;  3KL4 A;  3K66 A;  4WGZ A;  2HMZ A;  2YZS A;  4ULW A;  1YZC A;  1ZU4 A;  3QVZ A;  4EHP A;  4W8K A;  1A41 A;  2G3K A;  2MHR A;  3LAY A;  1EKY A;  3M1C B;  3Q7G A;  3X2Q C;  2R03 A;  1MQV A;  4O6N A;  1RMV A;  2QLA A;  2ZPA A;  1H6G A;  5IY5 C;  3IPM O;  2Y3B A;  2Z15 A;  1OW8 A;  1OQC A;  3KPH A;  1AEP A;  3FAP B;  4U9D A;  3DXJ F;  3JRM O;  4MVS A;  3J06 A;  3O55 A;  2A6E F;  1LE2 A;  2CNW A;  1BR2 A;  4L6R A;  1ZHZ A;  1GM5 A;  2V3C C;  3RVY A;  3GM3 A;  5D92 A;  4YWQ A;  2KSF A;  4MVO A;  5KYN A;  2R7W A;  4RD9 A;  3X1O A;  3U3B A;  3JT1 A;  3ASO C;  1J8M F;  1LE4 A;  4I3M A;  3LES A;  4JCZ A;  3B0U X;  1YYJ A;  5F28 E;  1VLT A;  3LNM B;  3FHD A;  1RKE B;  1VOM A;  2A68 F;  2KYH A;  4U5H A;  5DVW A;  1KU2 A;  3NKD A;  4ZLD A;  2CNW D;  1H9T A;  3N2Z B;  4ONS A;  5DQT A;  4MQ9 F;  5L3Q A;  5HSW A;  3RQF A;  5EK0 A;  1BBH A;  1QLE C;  2IOQ A;  4EWC A;  1SZI A;  1U6H A;  3DWW A;  1NBB A;  4H4K C;  4JW1 A;  3MFN A;  3TD7 A;  2HJM A;  1FFH A;  3PHF 2;  2HFI A;  3QMK A;  2LK4 A;  2EIM C;  2HKV A;  4HFK B;  2YLD A;  3EG9 A;  5A6K A;  3ATP A;  5D91 A;  1A7D A;  3U2M A;  3B71 A;  3IQT A;  2YWA A;  4MVZ A;  1APC A;  3SXY A;  3RIP A;  1OW6 A;  1IW7 F;  4JCH A;  5DLJ A;  5B3I A;  1YVI A;  3IQC A;  2L9J A;  4CS7 A;  3WAQ A;  3I5Q A;  1LVK A;  1MMN A;  4CS9 C;  2J0W A;  2AP3 A;  2LIG A;  3R7C A;  4H54 A;  2LP4 A;  4G7O F;  1Z5Z A;  3RKO F;  4AL1 A;  1VTM P;  4PFP A;  4OIN F;  5KYW A;  1RKC A;  1ZW2 A;  1G5Z A;  2KK1 A;  3TOM A;  1NFN A;  1WN0 A;  2XM0 A;  256B A;  3M4B A;  4DVZ A;  3U8V A;  3EQL F;  2PF4 E;  2J8W A;  5L0J A;  1JRA A;  3TJ5 A;  4C3D A;  4D4N A;  2B0J A;  2HZ8 A;  2WZG A;  3B0P A;  2J9U A;  1LKX A;  3GOD A;  2QUP A;  2GA0 A;  2WVQ A;  3B0V C;  2PX0 A;  3DJU B;  3F46 A;  3NMI A;  1E86 A;  2OKU A;  4XEV A;  3K7D A;  5DS5 A;  5L0C A;  2MWQ A;  4FAP B;  2YQY A;  2VCA A;  4YK5 A;  1Z6A A;  3RQE A;  3KYJ A;  2H8A A;  2JPU A;  2LQG A;  4K0D A;  3KMI A;  4MVQ A;  3C7J A;  4K7B A;  3KKB A;  3KYI A;  3UGP A;  2ZD9 A;  3T6G B;  2DYR C;  4W8P A;  3C8G D;  3ABK C;  1O5H A;  5DQZ A;  2KC3 A;  3IHU A;  2I15 A;  3S9O A;  3I5P A;  2J9B A;  1YAU O;  2R7Q A;  5T3T A;  1ZU5 A;  4ZLC A;  3W8H A;  4BJ5 C;  1WGW A;  1VK5 A;  2EIN C;  1H9G A;  5COF A;  2PNO A;  4BEM J;  5L0D A;  3T6J A;  4C3E A;  2R7X A;  3PDM P;  1OKK A;  2NSG A;  4JJF A;  2VC9 A;  4PJN A;  2HUJ A;  3NMJ A;  2XLD A;  3AGT A;  4XPW A;  2QE9 A;  4KC9 A;  5JUA A;  2O9X A;  3SEO A;  2GFH A;  4X0R A;  2Q7R A;  3V7O A;  4CDA A;  4LDR A;  5F5F A;  3K1H A;  4MND A;  3ASN C;  4MTG A;  1Q0K A;  4BJ6 C;  1QZX A;  2B0H A;  4DBR A;  4OIP F;  2JD3 A;  1YAR O;  4KBL A;  2NUT A;  4CX9 A;  3W8I A;  3FMS A;  2Y39 A;  5BUO A;  2GWW A;  2XLM A;  5KYW B;  3GWL A;  2F22 A;  1MND A;  1WAS A;  4N06 A;  4DOZ A;  3JYY A;  5COG A;  2JX0 A;  3NMK A;  4O7G A;  4E17 A;  3ZC4 A;  4LAC B;  1GS9 A;  2HJ3 A;  4DRJ B;  1G4U S;  2R9R B;  3LLK A;  4CS8 A;  5B3S C;  5DS6 A;  1BDJ B;  5L3V A;  3CAX A;  3AQC A;  2J45 A;  3K1I A;  1TWG A;  4I1O B;  1Z23 A;  3EGX A;  2WZF A;  1JMW A;  1RCP A;  1EQ1 A;  2LFD A;  4EBJ A;  4MW3 A;  3SXK A;  2EPK X;  3IQ5 A;  1PD0 A;  3KH2 A;  1EI7 A;  4M63 A;  3LLI A;  3NG1 A;  1VB5 A;  5FZT A;  4EBB A;  3SXM A;  1MMA A;  3WG7 C;  2EIJ C;  2EPL X;  5CI8 A;  2YL1 A;  4Z9H A;  4A4A A;  3EZH A;  3OA1 A;  1FMW A;  4YT4 A;  5A6B D;  5F5H A;  2WB7 A;  3FVY A;  1M57 C;  4U5B E;  4FWV A;  1FTS A;  1HW2 A;  2YLI A;  3NYJ A;  2H7O A;  3UMH A;  3M4C A;  4U5C E;  5K0I A;  2R7V A;  3JSE O;  1S05 A;  4C7O A;  3CZ6 A;  2Y3H A;  1JPJ A;  2XL6 A;  3K6B A;  5JT4 A;  1K04 A;  2L81 A;  3HNK A;  4GQH A;  4JUR I;  4XEF A;  3POV A;  1T5O A;  1LI7 A;  4J7T A;  4YN0 B;  3WHN A;  3ZQV A;  4HEA J;  2XLV A;  2XS1 A;  1G4W R;  1SF8 A;  4QI0 A;  4WGY A;  3T6B A;  1BR1 A;  2GDC A;  1JOG A;  4XWJ A;  1N1C A;  5BQG A;  1YDI A;  2X51 A;  3MYF A;  4Q4Z F;  2BC5 A;  4XPX A;  1OXK A;  2W4B A;  2OJQ A;  3V5Z A;  4PJL A;  1SMY F;  1ZYR F;  1NLX A;  4BG0 A;  1S7Z A;  2EIL C;  4N6H A;  4U5D E;  3TK0 A;  2OEV A;  4BJT A;  4YT8 A;  1XWJ A;  2HMQ A;  1YZA A;  2DB4 A;  1M56 C;  4CBE A;  4U5G A;  3SP1 A;  4JTA B;  2HSB A; 
#chains in the Genus database with same CATH homology
 1AUE A;  1NSG B;  4DRH B;  4DRI B;  5GPG B;  2FAP B;  4DRJ B;  2RSE B;  4FAP B;  3FAP B;  1FAP B;  2NPU A;  2GAQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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