4DRIB

Co-crystal structure of the ppiase domain of fkbp51, rapamycin and the frb fragment of mtor
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
96
structure length
96
Chain Sequence
GAMDPEFMEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRIS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Isomerase/transferase
source organism Homo sapiens
publication title Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin.
pubmed doi rcsb
molecule keywords Peptidyl-prolyl cis-trans isomerase FKBP5
total genus 38
structure length 96
sequence length 96
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2012-02-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.150 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) FKBP12-rapamycin binding domain 4driB00
1FAPB 3FAPB 1NSGB 4DRHB 4DRIB 2GAQA 2NPUA 4FAPB 2RSEB 4DRJB 5GPGB 1AUEA 2FAPB
chains in the Genus database with same CATH superfamily
3JSZA 2DYSC 1ZVZA 5L0IA 2Y69C 1E83A 5DQZA 4ANJA 1ZHYA 2BC5A 2R9RB 3C18A 1BBHA 2NSFA 4B6IA 4OIQF 4LERA 3TK0A 1ZHXA 3GEEA 2QLAA 3N24A 1FMWA 3LS1A 3HKKA 3L34A 3U5SA 1WGWA 3GANA 4PK4A 3UMKA 4DJ9A 1O3UA 3EHNA 3JRMO 2P6VA 1LI7A 1TKNA 3HJCA 2AWYA 1XZPA 5A6BA 1AEPA 3AG1C 2FFHA 3KYJA 2XLEA 4XPWA 4CS8A 5E2QA 4XEFA 2KC3A 2HV6A 2J7PA 4CX9A 3H2VA 3QZCA 2ETSA 5CI9A 2YL1A 2ZPAA 2Q7RA 4MVQA 3S27A 3EGXB 3V5XA 4LLEA 4U9DA 3S90A 3AGTA 1A7VA 4MNDA 5JT4A 1D0ZA 4BPMA 3TOLA 2IYLD 4XWJA 1ZHZA 4O6MA 4HFFB 2A69F 3GEHA 4Q7CA 3S0XA 2R7XA 2CGEA 3CEXA 1L7CA 2IOQA 3POVA 2HZ8A 2WZLA 2A6EF 4MS2A 4MVMA 1Q0GA 5L0DA 4DRJB 5A6JA 3C62A 3Q6NA 4JURI 1BDJB 2Q4FA 1E2XA 5AC5A 3UMIA 3Q7LA 2WVQA 3RIPA 3LNRA 2WVNA 3EFOA 2OEXA 1ZU4A 4CJOA 4PJMA 5L0GA 4QI0A 1EQ1A 3F47A 4CSAA 2H8AA 4ZLDA 2NUTB 3WHNA 1PD1A 5KYNA 1D0XA 4AL1A 1HE1A 1HMOA 1YJGA 1RXQA 1T5OA 3TJ6A 2XS1A 2PX3A 5EHHA 4MVUA 3NYLA 3B0PA 3C8GB 4FX5A 3X1OA 3JSEO 5DLJA 1T6UA 3RYLA 1DOVA 5KYXB 4I44A 4KI2A 2R7VA 1WN0A 1YDIA 3EGXA 4KC9A 3VYWA 4C3DA 2MHRA 3RKOF 3E9VA 1QSPA 4LDKA 4YT8A 1MNDA 4MTGA 2VCBA 2J45A 1S05A 3OA1A 5BQGA 1EI7A 1T6QA 2EIKC 4CBEA 4EKWA 4J7YA 3KPHA 4FWVA 3U2MA 1E86A 2DGJA 1M57C 4PJLA 4BJ5C 1TFOB 1H9TA 3CQZA 3FAJA 4RD9A 3S9OA 4CS9C 4H54A 4PACA 3MYFA 1YYXA 1D0YA 2VB6A 1VTMP 2HFIA 1NSGB 2NUTA 1GM5A 2F22A 2XL8A 3A9CA 4OIRF 1WOLA 1RJ9B 2ZD9A 1TWHA 3RF3A 2C03A 2Y3BA 3AQBA 1CGME 3M1CB 3AG2C 1OXBA 3HNLA 3RQGA 3GODA 3C8GA 3ZWIA 5L0HA 1VLSA 3K1IA 4JEBA 3B0UX 2PP4A 4A2NB 2P61A 3T9OA 5KYXA 1JR8A 2A68F 4JTAB 4U5HA 3U9JA 3B71A 4U5CE 5A6BD 3C7JA 5L0CA 1HE9A 3Q7GA 4O7GA 4K1OA 5T1DB 2XXAB 3T4RA 1U0BB 2B0HA 2J7PD 4RDAA 1I5NA 3TULA 2IXPA 4A4AA 2Y39A 3IPMO 4E18A 3ATPA 4DRHB 4YL1A 1XWJA 4BEMJ 1Z23A 1OCRC 1MMGA 2VCAA 2Q00A 1OR3A 4EUKB 4YT2A 3NMKA 4JE9A 2NG1A 3N0TA 5F5FA 2AWCA 3MFNA 5DS5A 2H7BA 2ASRA 2R02A 3ASNC 2J0WA 2M4EA 2M64A 2W9YA 1ZYRF 2YLDA 2XSEA 1H7IA 1SYQA 3C8ZA 3SEOA 1HW1A 2NPUA 3NYMA 4N06A 3V5ZA 3K33A 4F4BA 1F1MA 2W45A 2QY9A 4EWCA 2KQ9A 1T01A 2LSEA 3AG4C 1RJ9A 3DAFA 3AJMA 3JRTA 3RW0A 4BJTA 1WWPA 3IQ6A 5JS5A 4G7ZF 2R7OA 1Z6AA 4WGZA 4MVZA 4OD4A 2YL3A 4M63A 1V55C 4GEHA 4GQHA 4G7HF 2V26A 3JZ0A 3G4XA 2OEVA 2WL8A 4IGGA 3QTHA 2G3VA 4DVZA 4DBRA 4EBJA 5A6AA 4JRZA 3PHF2 3EG9B 3W8HA 3X2QC 2X51A 3ASOC 2QTVA 1LKXA 3U0CA 4JZAA 4BJ6C 5FCLA 5KYWB 5JP7A 4NTFA 1T6IA 4OD5A 2IBFA 4Q5SF 1E84A 3S28A 3B29A 5B3IA 5A6KA 3PDMP 1HW2A 3DMDA 3QMKA 3ECSA 3KMIA 3EFOB 4G78A 4BJ6A 3ITFA 4YWQA 2YL7A 1OR2A 2IXMA 3ZG1A 4U5FE 4CS8C 4HFKB 1BR2A 1OCOC 4IRUA 1ZW2A 3EHMA 3B9QA 5D91A 1G8XA 1VMAA 3EZHA 1E85A 2R03A 2XLHA 5F5HA 2GDCA 4XQ1A 1QLEC 1YYJA 2J9VA 1G4WR 4P9TA 4D4NA 1TWCA 3LLIA 4K0DA 2WB7A 2LP4A 4J30B 2R7UA 1M56C 4K7BA 5JLIA 4G7OF 2MWQA 2HUJA 2HMQA 3RVZA 1LIHA 4C3EA 3IQCA 1TQGA 2DI3A 3CZ6A 1PD0A 2HKVA 2J9UA 4YL0A 4YT5A 1NU9C 1OCCC 3WODF 3MX3A 4JCHA 5DS6A 2J0XA 1OCZC 2KNHA 3M4BA 3SXKA 5KYUB 5AC4A 1OW7A 3IHUA 1Z5ZA 2KYHA 2YVKA 4DXWA 1KNYA 3AQCA 5JUAA 1VOMA 2EIJC 1M6TA 2J8WA 3ABMC 3C8GD 3EG9A 2H7OA 3NRHA 2L6GA 3LEOA 4I3MA 2TMVP 1B68A 4Z9JA 3LS0A 3K1HA 2GFHA 4O6YA 3TQOA 1OKKA 3O6XA 1BZ4A 4E0HA 2YZSA 3L8IA 2L6FA 4J7TA 5JSLA 4FAPB 4C7OB 256BA 4EHPA 4MW8A 3NG1A 4CIPA 4EBBA 4XTKA 3DE9A 1QPUA 5F28E 1BR4A 2ZXOA 4JIOA 1JPJA 1QVXA 4MTOA 4MW3A 3IQ5A 1C17M 1D1CA 3EH1A 4ZLCA 1EKYA 3O10A 4YJWA 4NC3A 4DOZA 2ZXRA 2I8BA 1H9GA 3GM3A 2D5RB 2P0NA 3JCUQ 4BJ1A 2E87A 2OOCA 1FTSA 1LPEA 1GS9A 2Q9BA 4W8PA 2L7AA 1RMVA 3NDBB 1N1CA 4E7ZA 3RH3A 1V54C 4N6CA 2IM8A 2LK4A 2RSEB 1T9KA 2QNLA 3KH2A 1FFTC 4PFOA 5KYUA 5L0FA 3MLGA 3HTKC 4IARA 1Z7Qc 2XRHA 1RKEB 2OJQA 2EPOA 3SXZA 1J8MF 4LLCA 3ZVRA 3L8JA 2AP3A 1R4TA 1ZHTA 3S29A 5JRAA 1QKRA 2XM4A 2YLIA 3I5PA 3FVYA 3A11A 1A0BA 3TOMA 2Z15A 2W4BA 3Q6MA 1HMDA 3CSKA 4C7OA 3KYIA 2YHSA 3LUTB 2OG2A 2OKUA 2CDQA 1RCPA 4HE8D 1AVOB 2A1DD 2EILC 2UUHA 5K0IA 4N6HA 2LFDA 2PF4E 1EA8A 3K6BA 4I1MA 3US6A 1DOWA 1Q0KA 1VYIA 1VB5A 1I4ZA 2A0BA 3ABKC 3K1IC 1IW7F 3K66A 2HJ3A 3NMJA 4XPXA 3VAYA 2R7WA 1JAFA 4MVSA 5E33A 5HSWA 1L3PA 5COMA 1ORYA 4KBLA 1Q0FA 2HJMA 3LAYA 3ZSUA 4G0HA 4IB4A 2XM0A 2VC9A 2ZXWC 4E0IA 1VK5A 2AU5A 2I15A 3ZTMA 5CIVA 3H65A 3TJ5A 2L6HA 1FMVA 2UUIA 5CI8A 2G62A 1NG1A 3VM6A 1TFKB 4L6RA 1M2VB 1RKEA 2R25A 3DM9B 3O39A 4WJ0A 1S7ZA 4D4XA 3NKEA 3UMHA 1UFBA 1FR0A 5KYYB 3DXJF 4LDQA 2J9BA 3LNMB 4CDVA 2EPLX 2XL4A 3UR3C 4MQ9F 2IXOA 4O6NA 1Z3IX 3BRJA 2KGOA 1YLMA 2Q3TA 1ZHWA 2A6HF 2P1AA 2R7SA 4MVOA 1A7DA 3EJNA 3S84A 3U3BA 4WABA 3LLKA 3DI5A 3E70C 2EPKX 3SNHA 1V74B 2KJGA 1FAPB 3NKDA 1LE4A 2GA0A 3IQTA 1CGOA 2GAQA 4I1OB 3JTLO 4P9FA 2RD9A 4U5BE 3PMRA 2NUPB 2KW3C 4FESA 1TWAA 3RQEA 2G3KA 2PNOA 1UG7A 4XPYA 1LE2A 1RKCA 5L0JA 3EH2A 2XLDA 2CCYA 4J32B 1MMAA 1LS1A 1HY5A 1Y6DA 2QUPA 3GORA 3H2UA 3JYYA 4CDAA 1AUEA 3PCVA 1ZW3A 1OXKA 3M15A 1M2VA 2LD6A 4EBKA 2YQYA 1Z63A 2A0UA 2XS8A 4CJGA 4JJGA 1PCXA 1O5HA 4NTBA 1A7EA 1VYKA 3U8PA 5KYYA 1FNTc 5B3SC 2HV7A 1MNEA 4PR9A 3W8IA 4JTDB 3AG3C 2ZXPA 4YN0B 3ZC4A 2VASA 2OJED 1PV3A 1OW8A 4DBQA 4XLPF 1YAUO 3R2PA 4IJJA 2OU6A 2Y3GA 4JEAA 1OW6A 1APCA 2EINC 5GPGB 2FAPB 4PJNA 3MBGA 2IXNA 4QDLA 1NZEA 5COGA 3FHDA 4CSAC 4AL0A 3M79A 3WAQA 4ONSA 4E7SA 4U9EA 2LIGA 3EZIA 4LACB 2CNWA 2NUPA 5DQTA 3GM2A 1C02A 2LCHA 4DRIB 1Q0DA 2DB4A 2XLWA 3KKBA 1TWGA 2HMZA 4NCQA 1CPQA 1ORJA 3LJBA 2Y3DA 5JVEA 2L9JA 3GWLA 1YZAA 1ZZPA 2LQGA 2VH3A 5T3TA 1I4YA 5DVWA 2JX0A 5E3AA 1NBBA 1FFHA 5T3WA 3LEVA 1WASA 1LI5A 3SZRA 3V7OA 4E17A 2YL0A 3DKAA 3OEOA 4X0RA 3UNGC 1K05A 3KL4A 3W4YA 1G5ZA 2HSBA 2QE9A 3SXYA 4OIPF 3DE8A 3OWTA 2DYRC 4IWBA 4KNWA 3RFYA 1NLXA 3JT1A 4BG0A 3R7CA 2R05A 4GYTA 4Z9IA 2WVOA 3QVZA 1TR2A 3HNJA 4ULWA 3G50A 2VCCA 1JMWA 1D1BA 3F46A 4IAQA 3G4ZA 1JRAA 2EIMC 3NYJA 4RBNA 4YK5A 4HEAJ 2BL2A 4YT4A 3FXHA 5L3VA 3MYIA 5FZTA 3EPVA 3HNKA 2YEVA 1WATA 2YLGA 4Z9HA 5BQIA 1YA9A 5D92A 3DJNB 1M2OA 3DAGA 2EPMX 1O87A 3V5YA 3T6GB 4N4WA 1ST6A 2GWWA 4IAOA 2KK1A 1YARO 3FOPA 3DJUB 3GM1A 1WTYA 3T6BA 4U5GA 3U2LA 1SMYF 3FDQA 2B0JA 1LVKA 3BEHA 3ZQYA 1KU2A 2Y3HA 2D4UA 5AGFA 1YZCA 3DD7A 3EQLF 1CPRA 2HSQA 3W2WA 3ZQVA 4DVYP 2Q9CA 4ER9A 1QQ3A 2FGYA 3EGDB 4U5DE 4WGYA 2C04A 4OINF 4BEJA 1KTMA 3DWWA 1OQCA 2O9XA 3HNIA 3FOOA 3GWNA 2CYDA 2W4MA 1CGNA 2NSGA 2WZGA 4JW1A 3VRCA 5BQHA 3AGUA 1XZQA 3U8VA 4QI2A 2XXAA 1SR2A 3GEIA 3AOUA 1GQAA 4JCZA 3B0VC 2EPNA 1JOGA 2OQMA 1VLTA 3QVYA 4PFPA 3SYNA 3DM5A 5B1AC 1V4AA 2WZFA 4O79A 4Q4ZF 2JD3A 1U6HA 2L81A 3O55A 2XLOA 5EGYA 3ZDLA 3W2VA 3UGPA 2Q9AA 3FMSA 5KYWA 3CAXA 4JKVA 5COFA 3L1MA 3IEEA 4XEVA 1Q0MA 1MMDA 2P7VA 4BJ5A 4CIHA 1MQVA 3SP1A 1D1AA 2KSFA 4AE4B 3ZIBA 4CS9A 1NFNA 4NTAA 1Y4CA 2CNWD 2ICWG 5B1BC 1K04A 3ZTZA 5IY5C 1IZMA 1NU7D 3SXMA 4P6IC 3VF0A 2JPUA 3WG7C 2XLMA 1JPNA 2YRFA 3EGDA 3NMIA 4PJJA 4YL3A 1G4US 5DS4A 4XLNF 3TD7A 2XL6A 3J06A 4EIYA 3K7DA 2R7QA 4U5EE 3HLZA 2YKZA 3I5QA 4XEKA 1U89A 1OKKD 2J46A 2PX0A 2LFFA 4JC7A 2OCCC 3I4UA 2V3CC 1C03A 3N2ZB 1LM3B 3DZAA 4LDRA 3LESA 2HS5A 1R5ID 4W8KA 1GGQA 1NFOA 2AVKA 5TJ5E 4R32A 1YVIA 4JJFA 4JVSA 3U3FA 1A41A 1YA7O 1H6GA 2YWAA 3JYHA 3UGOA 1ZU5A 1ORSC 3RQFA 1J8YF 2PFDA 5HV9A 4AX2A 2XLVA 3ABLC 4AE4A 4MTFA 3T6JA 4C3BA 5A69A 4NQFA 2H7VC 3U9MA 1W2WA 3L0IA 4ULVA 2BE5F 2MYSA 5EK0A 2X0CA 4JTCB 2CW0F 3C63A 1MMNA 3M4CA 1QZXA 4CDYA 4KNVA 5E3CA 4UDVA 2PBEA 1BR1A 1SF8A 4CS7A 5BUOA 1K40A 4OIOF 4MVRA 3RVYA 3QW1A 1LS4A 3FAPB 3QW0A 4AK9A 2R7TA 4H4KC 2R7RA 2J9WA 5L3QA 1SZIA 4NY3A
chains in the Genus database with same CATH topology
1FAPB 3FAPB 1NSGB 4DRHB 4DRIB 2GAQA 2NPUA 4FAPB 2RSEB 4DRJB 5GPGB 1AUEA 2FAPB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FAP B;  3FAP B;  1NSG B;  4DRH B;  4DRI B;  2GAQ A;  2NPU A;  4FAP B;  2RSE B;  4DRJ B;  5GPG B;  1AUE A;  2FAP B; 
#chains in the Genus database with same CATH topology
 3JSZ A;  2DYS C;  1ZVZ A;  5L0I A;  2Y69 C;  1E83 A;  5DQZ A;  4ANJ A;  1ZHY A;  2BC5 A;  2R9R B;  3C18 A;  1BBH A;  2NSF A;  4B6I A;  4OIQ F;  4LER A;  3TK0 A;  1ZHX A;  3GEE A;  2QLA A;  3N24 A;  1FMW A;  3LS1 A;  3HKK A;  3L34 A;  3U5S A;  1WGW A;  3GAN A;  4PK4 A;  3UMK A;  4DJ9 A;  1O3U A;  3EHN A;  3JRM O;  2P6V A;  1LI7 A;  1TKN A;  3HJC A;  2AWY A;  1XZP A;  5A6B A;  1AEP A;  3AG1 C;  2FFH A;  3KYJ A;  2XLE A;  4XPW A;  4CS8 A;  5E2Q A;  4XEF A;  2KC3 A;  2HV6 A;  2J7P A;  4CX9 A;  3H2V A;  3QZC A;  2ETS A;  5CI9 A;  2YL1 A;  2ZPA A;  2Q7R A;  4MVQ A;  3S27 A;  3EGX B;  3V5X A;  4LLE A;  4U9D A;  3S90 A;  3AGT A;  1A7V A;  4MND A;  5JT4 A;  1D0Z A;  4BPM A;  3TOL A;  2IYL D;  4XWJ A;  1ZHZ A;  4O6M A;  4HFF B;  2A69 F;  3GEH A;  4Q7C A;  3S0X A;  2R7X A;  2CGE A;  3CEX A;  1L7C A;  2IOQ A;  3POV A;  2HZ8 A;  2WZL A;  2A6E F;  4MS2 A;  4MVM A;  1Q0G A;  5L0D A;  4DRJ B;  5A6J A;  3C62 A;  3Q6N A;  4JUR I;  1BDJ B;  2Q4F A;  1E2X A;  5AC5 A;  3UMI A;  3Q7L A;  2WVQ A;  3RIP A;  3LNR A;  2WVN A;  3EFO A;  2OEX A;  1ZU4 A;  4CJO A;  4PJM A;  5L0G A;  4QI0 A;  1EQ1 A;  3F47 A;  4CSA A;  2H8A A;  4ZLD A;  2NUT B;  3WHN A;  1PD1 A;  5KYN A;  1D0X A;  4AL1 A;  1HE1 A;  1HMO A;  1YJG A;  1RXQ A;  1T5O A;  3TJ6 A;  2XS1 A;  2PX3 A;  5EHH A;  4MVU A;  3NYL A;  3B0P A;  3C8G B;  4FX5 A;  3X1O A;  3JSE O;  5DLJ A;  1T6U A;  3RYL A;  1DOV A;  5KYX B;  4I44 A;  4KI2 A;  2R7V A;  1WN0 A;  1YDI A;  3EGX A;  4KC9 A;  3VYW A;  4C3D A;  2MHR A;  3RKO F;  3E9V A;  1QSP A;  4LDK A;  4YT8 A;  1MND A;  4MTG A;  2VCB A;  2J45 A;  1S05 A;  3OA1 A;  5BQG A;  1EI7 A;  1T6Q A;  2EIK C;  4CBE A;  4EKW A;  4J7Y A;  3KPH A;  4FWV A;  3U2M A;  1E86 A;  2DGJ A;  1M57 C;  4PJL A;  4BJ5 C;  1TFO B;  1H9T A;  3CQZ A;  3FAJ A;  4RD9 A;  3S9O A;  4CS9 C;  4H54 A;  4PAC A;  3MYF A;  1YYX A;  1D0Y A;  2VB6 A;  1VTM P;  2HFI A;  1NSG B;  2NUT A;  1GM5 A;  2F22 A;  2XL8 A;  3A9C A;  4OIR F;  1WOL A;  1RJ9 B;  2ZD9 A;  1TWH A;  3RF3 A;  2C03 A;  2Y3B A;  3AQB A;  1CGM E;  3M1C B;  3AG2 C;  1OXB A;  3HNL A;  3RQG A;  3GOD A;  3C8G A;  3ZWI A;  5L0H A;  1VLS A;  3K1I A;  4JEB A;  3B0U X;  2PP4 A;  4A2N B;  2P61 A;  3T9O A;  5KYX A;  1JR8 A;  2A68 F;  4JTA B;  4U5H A;  3U9J A;  3B71 A;  4U5C E;  5A6B D;  3C7J A;  5L0C A;  1HE9 A;  3Q7G A;  4O7G A;  4K1O A;  5T1D B;  2XXA B;  3T4R A;  1U0B B;  2B0H A;  2J7P D;  4RDA A;  1I5N A;  3TUL A;  2IXP A;  4A4A A;  2Y39 A;  3IPM O;  4E18 A;  3ATP A;  4DRH B;  4YL1 A;  1XWJ A;  4BEM J;  1Z23 A;  1OCR C;  1MMG A;  2VCA A;  2Q00 A;  1OR3 A;  4EUK B;  4YT2 A;  3NMK A;  4JE9 A;  2NG1 A;  3N0T A;  5F5F A;  2AWC A;  3MFN A;  5DS5 A;  2H7B A;  2ASR A;  2R02 A;  3ASN C;  2J0W A;  2M4E A;  2M64 A;  2W9Y A;  1ZYR F;  2YLD A;  2XSE A;  1H7I A;  1SYQ A;  3C8Z A;  3SEO A;  1HW1 A;  2NPU A;  3NYM A;  4N06 A;  3V5Z A;  3K33 A;  4F4B A;  1F1M A;  2W45 A;  2QY9 A;  4EWC A;  2KQ9 A;  1T01 A;  2LSE A;  3AG4 C;  1RJ9 A;  3DAF A;  3AJM A;  3JRT A;  3RW0 A;  4BJT A;  1WWP A;  3IQ6 A;  5JS5 A;  4G7Z F;  2R7O A;  1Z6A A;  4WGZ A;  4MVZ A;  4OD4 A;  2YL3 A;  4M63 A;  1V55 C;  4GEH A;  4GQH A;  4G7H F;  2V26 A;  3JZ0 A;  3G4X A;  2OEV A;  2WL8 A;  4IGG A;  3QTH A;  2G3V A;  4DVZ A;  4DBR A;  4EBJ A;  5A6A A;  4JRZ A;  3PHF 2;  3EG9 B;  3W8H A;  3X2Q C;  2X51 A;  3ASO C;  2QTV A;  1LKX A;  3U0C A;  4JZA A;  4BJ6 C;  5FCL A;  5KYW B;  5JP7 A;  4NTF A;  1T6I A;  4OD5 A;  2IBF A;  4Q5S F;  1E84 A;  3S28 A;  3B29 A;  5B3I A;  5A6K A;  3PDM P;  1HW2 A;  3DMD A;  3QMK A;  3ECS A;  3KMI A;  3EFO B;  4G78 A;  4BJ6 A;  3ITF A;  4YWQ A;  2YL7 A;  1OR2 A;  2IXM A;  3ZG1 A;  4U5F E;  4CS8 C;  4HFK B;  1BR2 A;  1OCO C;  4IRU A;  1ZW2 A;  3EHM A;  3B9Q A;  5D91 A;  1G8X A;  1VMA A;  3EZH A;  1E85 A;  2R03 A;  2XLH A;  5F5H A;  2GDC A;  4XQ1 A;  1QLE C;  1YYJ A;  2J9V A;  1G4W R;  4P9T A;  4D4N A;  1TWC A;  3LLI A;  4K0D A;  2WB7 A;  2LP4 A;  4J30 B;  2R7U A;  1M56 C;  4K7B A;  5JLI A;  4G7O F;  2MWQ A;  2HUJ A;  2HMQ A;  3RVZ A;  1LIH A;  4C3E A;  3IQC A;  1TQG A;  2DI3 A;  3CZ6 A;  1PD0 A;  2HKV A;  2J9U A;  4YL0 A;  4YT5 A;  1NU9 C;  1OCC C;  3WOD F;  3MX3 A;  4JCH A;  5DS6 A;  2J0X A;  1OCZ C;  2KNH A;  3M4B A;  3SXK A;  5KYU B;  5AC4 A;  1OW7 A;  3IHU A;  1Z5Z A;  2KYH A;  2YVK A;  4DXW A;  1KNY A;  3AQC A;  5JUA A;  1VOM A;  2EIJ C;  1M6T A;  2J8W A;  3ABM C;  3C8G D;  3EG9 A;  2H7O A;  3NRH A;  2L6G A;  3LEO A;  4I3M A;  2TMV P;  1B68 A;  4Z9J A;  3LS0 A;  3K1H A;  2GFH A;  4O6Y A;  3TQO A;  1OKK A;  3O6X A;  1BZ4 A;  4E0H A;  2YZS A;  3L8I A;  2L6F A;  4J7T A;  5JSL A;  4FAP B;  4C7O B;  256B A;  4EHP A;  4MW8 A;  3NG1 A;  4CIP A;  4EBB A;  4XTK A;  3DE9 A;  1QPU A;  5F28 E;  1BR4 A;  2ZXO A;  4JIO A;  1JPJ A;  1QVX A;  4MTO A;  4MW3 A;  3IQ5 A;  1C17 M;  1D1C A;  3EH1 A;  4ZLC A;  1EKY A;  3O10 A;  4YJW A;  4NC3 A;  4DOZ A;  2ZXR A;  2I8B A;  1H9G A;  3GM3 A;  2D5R B;  2P0N A;  3JCU Q;  4BJ1 A;  2E87 A;  2OOC A;  1FTS A;  1LPE A;  1GS9 A;  2Q9B A;  4W8P A;  2L7A A;  1RMV A;  3NDB B;  1N1C A;  4E7Z A;  3RH3 A;  1V54 C;  4N6C A;  2IM8 A;  2LK4 A;  2RSE B;  1T9K A;  2QNL A;  3KH2 A;  1FFT C;  4PFO A;  5KYU A;  5L0F A;  3MLG A;  3HTK C;  4IAR A;  1Z7Q c;  2XRH A;  1RKE B;  2OJQ A;  2EPO A;  3SXZ A;  1J8M F;  4LLC A;  3ZVR A;  3L8J A;  2AP3 A;  1R4T A;  1ZHT A;  3S29 A;  5JRA A;  1QKR A;  2XM4 A;  2YLI A;  3I5P A;  3FVY A;  3A11 A;  1A0B A;  3TOM A;  2Z15 A;  2W4B A;  3Q6M A;  1HMD A;  3CSK A;  4C7O A;  3KYI A;  2YHS A;  3LUT B;  2OG2 A;  2OKU A;  2CDQ A;  1RCP A;  4HE8 D;  1AVO B;  2A1D D;  2EIL C;  2UUH A;  5K0I A;  4N6H A;  2LFD A;  2PF4 E;  1EA8 A;  3K6B A;  4I1M A;  3US6 A;  1DOW A;  1Q0K A;  1VYI A;  1VB5 A;  1I4Z A;  2A0B A;  3ABK C;  3K1I C;  1IW7 F;  3K66 A;  2HJ3 A;  3NMJ A;  4XPX A;  3VAY A;  2R7W A;  1JAF A;  4MVS A;  5E33 A;  5HSW A;  1L3P A;  5COM A;  1ORY A;  4KBL A;  1Q0F A;  2HJM A;  3LAY A;  3ZSU A;  4G0H A;  4IB4 A;  2XM0 A;  2VC9 A;  2ZXW C;  4E0I A;  1VK5 A;  2AU5 A;  2I15 A;  3ZTM A;  5CIV A;  3H65 A;  3TJ5 A;  2L6H A;  1FMV A;  2UUI A;  5CI8 A;  2G62 A;  1NG1 A;  3VM6 A;  1TFK B;  4L6R A;  1M2V B;  1RKE A;  2R25 A;  3DM9 B;  3O39 A;  4WJ0 A;  1S7Z A;  4D4X A;  3NKE A;  3UMH A;  1UFB A;  1FR0 A;  5KYY B;  3DXJ F;  4LDQ A;  2J9B A;  3LNM B;  4CDV A;  2EPL X;  2XL4 A;  3UR3 C;  4MQ9 F;  2IXO A;  4O6N A;  1Z3I X;  3BRJ A;  2KGO A;  1YLM A;  2Q3T A;  1ZHW A;  2A6H F;  2P1A A;  2R7S A;  4MVO A;  1A7D A;  3EJN A;  3S84 A;  3U3B A;  4WAB A;  3LLK A;  3DI5 A;  3E70 C;  2EPK X;  3SNH A;  1V74 B;  2KJG A;  1FAP B;  3NKD A;  1LE4 A;  2GA0 A;  3IQT A;  1CGO A;  2GAQ A;  4I1O B;  3JTL O;  4P9F A;  2RD9 A;  4U5B E;  3PMR A;  2NUP B;  2KW3 C;  4FES A;  1TWA A;  3RQE A;  2G3K A;  2PNO A;  1UG7 A;  4XPY A;  1LE2 A;  1RKC A;  5L0J A;  3EH2 A;  2XLD A;  2CCY A;  4J32 B;  1MMA A;  1LS1 A;  1HY5 A;  1Y6D A;  2QUP A;  3GOR A;  3H2U A;  3JYY A;  4CDA A;  1AUE A;  3PCV A;  1ZW3 A;  1OXK A;  3M15 A;  1M2V A;  2LD6 A;  4EBK A;  2YQY A;  1Z63 A;  2A0U A;  2XS8 A;  4CJG A;  4JJG A;  1PCX A;  1O5H A;  4NTB A;  1A7E A;  1VYK A;  3U8P A;  5KYY A;  1FNT c;  5B3S C;  2HV7 A;  1MNE A;  4PR9 A;  3W8I A;  4JTD B;  3AG3 C;  2ZXP A;  4YN0 B;  3ZC4 A;  2VAS A;  2OJE D;  1PV3 A;  1OW8 A;  4DBQ A;  4XLP F;  1YAU O;  3R2P A;  4IJJ A;  2OU6 A;  2Y3G A;  4JEA A;  1OW6 A;  1APC A;  2EIN C;  5GPG B;  2FAP B;  4PJN A;  3MBG A;  2IXN A;  4QDL A;  1NZE A;  5COG A;  3FHD A;  4CSA C;  4AL0 A;  3M79 A;  3WAQ A;  4ONS A;  4E7S A;  4U9E A;  2LIG A;  3EZI A;  4LAC B;  2CNW A;  2NUP A;  5DQT A;  3GM2 A;  1C02 A;  2LCH A;  4DRI B;  1Q0D A;  2DB4 A;  2XLW A;  3KKB A;  1TWG A;  2HMZ A;  4NCQ A;  1CPQ A;  1ORJ A;  3LJB A;  2Y3D A;  5JVE A;  2L9J A;  3GWL A;  1YZA A;  1ZZP A;  2LQG A;  2VH3 A;  5T3T A;  1I4Y A;  5DVW A;  2JX0 A;  5E3A A;  1NBB A;  1FFH A;  5T3W A;  3LEV A;  1WAS A;  1LI5 A;  3SZR A;  3V7O A;  4E17 A;  2YL0 A;  3DKA A;  3OEO A;  4X0R A;  3UNG C;  1K05 A;  3KL4 A;  3W4Y A;  1G5Z A;  2HSB A;  2QE9 A;  3SXY A;  4OIP F;  3DE8 A;  3OWT A;  2DYR C;  4IWB A;  4KNW A;  3RFY A;  1NLX A;  3JT1 A;  4BG0 A;  3R7C A;  2R05 A;  4GYT A;  4Z9I A;  2WVO A;  3QVZ A;  1TR2 A;  3HNJ A;  4ULW A;  3G50 A;  2VCC A;  1JMW A;  1D1B A;  3F46 A;  4IAQ A;  3G4Z A;  1JRA A;  2EIM C;  3NYJ A;  4RBN A;  4YK5 A;  4HEA J;  2BL2 A;  4YT4 A;  3FXH A;  5L3V A;  3MYI A;  5FZT A;  3EPV A;  3HNK A;  2YEV A;  1WAT A;  2YLG A;  4Z9H A;  5BQI A;  1YA9 A;  5D92 A;  3DJN B;  1M2O A;  3DAG A;  2EPM X;  1O87 A;  3V5Y A;  3T6G B;  4N4W A;  1ST6 A;  2GWW A;  4IAO A;  2KK1 A;  1YAR O;  3FOP A;  3DJU B;  3GM1 A;  1WTY A;  3T6B A;  4U5G A;  3U2L A;  1SMY F;  3FDQ A;  2B0J A;  1LVK A;  3BEH A;  3ZQY A;  1KU2 A;  2Y3H A;  2D4U A;  5AGF A;  1YZC A;  3DD7 A;  3EQL F;  1CPR A;  2HSQ A;  3W2W A;  3ZQV A;  4DVY P;  2Q9C A;  4ER9 A;  1QQ3 A;  2FGY A;  3EGD B;  4U5D E;  4WGY A;  2C04 A;  4OIN F;  4BEJ A;  1KTM A;  3DWW A;  1OQC A;  2O9X A;  3HNI A;  3FOO A;  3GWN A;  2CYD A;  2W4M A;  1CGN A;  2NSG A;  2WZG A;  4JW1 A;  3VRC A;  5BQH A;  3AGU A;  1XZQ A;  3U8V A;  4QI2 A;  2XXA A;  1SR2 A;  3GEI A;  3AOU A;  1GQA A;  4JCZ A;  3B0V C;  2EPN A;  1JOG A;  2OQM A;  1VLT A;  3QVY A;  4PFP A;  3SYN A;  3DM5 A;  5B1A C;  1V4A A;  2WZF A;  4O79 A;  4Q4Z F;  2JD3 A;  1U6H A;  2L81 A;  3O55 A;  2XLO A;  5EGY A;  3ZDL A;  3W2V A;  3UGP A;  2Q9A A;  3FMS A;  5KYW A;  3CAX A;  4JKV A;  5COF A;  3L1M A;  3IEE A;  4XEV A;  1Q0M A;  1MMD A;  2P7V A;  4BJ5 A;  4CIH A;  1MQV A;  3SP1 A;  1D1A A;  2KSF A;  4AE4 B;  3ZIB A;  4CS9 A;  1NFN A;  4NTA A;  1Y4C A;  2CNW D;  2ICW G;  5B1B C;  1K04 A;  3ZTZ A;  5IY5 C;  1IZM A;  1NU7 D;  3SXM A;  4P6I C;  3VF0 A;  2JPU A;  3WG7 C;  2XLM A;  1JPN A;  2YRF A;  3EGD A;  3NMI A;  4PJJ A;  4YL3 A;  1G4U S;  5DS4 A;  4XLN F;  3TD7 A;  2XL6 A;  3J06 A;  4EIY A;  3K7D A;  2R7Q A;  4U5E E;  3HLZ A;  2YKZ A;  3I5Q A;  4XEK A;  1U89 A;  1OKK D;  2J46 A;  2PX0 A;  2LFF A;  4JC7 A;  2OCC C;  3I4U A;  2V3C C;  1C03 A;  3N2Z B;  1LM3 B;  3DZA A;  4LDR A;  3LES A;  2HS5 A;  1R5I D;  4W8K A;  1GGQ A;  1NFO A;  2AVK A;  5TJ5 E;  4R32 A;  1YVI A;  4JJF A;  4JVS A;  3U3F A;  1A41 A;  1YA7 O;  1H6G A;  2YWA A;  3JYH A;  3UGO A;  1ZU5 A;  1ORS C;  3RQF A;  1J8Y F;  2PFD A;  5HV9 A;  4AX2 A;  2XLV A;  3ABL C;  4AE4 A;  4MTF A;  3T6J A;  4C3B A;  5A69 A;  4NQF A;  2H7V C;  3U9M A;  1W2W A;  3L0I A;  4ULV A;  2BE5 F;  2MYS A;  5EK0 A;  2X0C A;  4JTC B;  2CW0 F;  3C63 A;  1MMN A;  3M4C A;  1QZX A;  4CDY A;  4KNV A;  5E3C A;  4UDV A;  2PBE A;  1BR1 A;  1SF8 A;  4CS7 A;  5BUO A;  1K40 A;  4OIO F;  4MVR A;  3RVY A;  3QW1 A;  1LS4 A;  3FAP B;  3QW0 A;  4AK9 A;  2R7T A;  4H4K C;  2R7R A;  2J9W A;  5L3Q A;  1SZI A;  4NY3 A; 
#chains in the Genus database with same CATH homology
 1FAP B;  3FAP B;  1NSG B;  4DRH B;  4DRI B;  2GAQ A;  2NPU A;  4FAP B;  2RSE B;  4DRJ B;  5GPG B;  1AUE A;  2FAP B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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