4JCZA

Human ltc4 synthase in complex with product analogs - implications for enzyme catalysis
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
147
structure length
147
Chain Sequence
HHKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVALAALGLLAHFLPAALRAALLGRLRTL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords Leukotriene C4 synthase
total genus 60
structure length 147
sequence length 147
ec nomenclature ec 4.4.1.20: Leukotriene-C(4) synthase.
pdb deposition date 2013-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01124 MAPEG MAPEG family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.550 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Membrane associated eicosanoid/glutathione metabolism-like domain 4jczA00
4JC7A 3PCVA 3DWWA 5BQIA 4NTBA 4YL1A 5BQHA 4J7YA 5K0IA 2UUIA 2UUHA 4J7TA 2Q7RA 2PNOA 3B29A 4JRZA 4NTAA 4YK5A 4JCZA 4WABA 4NTFA 3HKKA 4YL0A 4BPMA 5HV9A 5BQGA 4AL1A 2H8AA 3LEOA 4YL3A 4AL0A
chains in the Genus database with same CATH superfamily
3AG3C 1L7CA 2NUTB 2KQ9A 4ANJA 2A0UA 3K33A 1APCA 2FAPB 3EZHA 4J7YA 1Z23A 2OJQA 2HSBA 3AGUA 1LIHA 2GWWA 1YYJA 3B0VC 3VYWA 2OCCC 4XQ1A 1YVIA 1JOGA 3JRMO 4C7OB 4EBKA 4XEKA 3U9MA 4KC9A 1YYXA 3FMSA 5JP7A 3G50A 4JIOA 4JTCB 2KC3A 4DJ9A 4JTAB 1R4TA 2YZSA 4W8PA 4XPWA 2EIMC 3C8GA 3LS1A 3Q7GA 5DVWA 2A1DD 4E7ZA 4CJOA 3TQOA 5E3AA 3GODA 4AE4A 1QPUA 3RVYA 1C03A 1FFTC 1D1BA 2KK1A 2P0NA 3H2VA 3T6JA 3T6BA 1HE9A 3O39A 5GPGB 3NDBB 1LI5A 3V5ZA 1TWGA 2YL3A 5E2QA 5COMA 4MTOA 1Z7Qc 4CSAC 3Q6NA 1SZIA 1ZZPA 4E17A 1O3UA 3K66A 5KYXA 3UMKA 1NFOA 1ZHWA 2YLGA 2HKVA 1NSGB 2HV7A 2ZXPA 3EJNA 3LEVA 3F47A 2RD9A 4U9EA 4DOZA 3ECSA 1U6HA 4F4BA 3L34A 1WWPA 3NYJA 2Q9BA 5B1AC 4DVZA 5JRAA 2GA0A 1YA9A 1YLMA 4LACB 3B0PA 3IPMO 2ZXOA 4JEAA 1J8YF 2I8BA 2Q00A 3DM9B 3FXHA 5DS4A 4OIPF 3O6XA 1HW2A 3V5YA 4LDKA 2LP4A 4XPYA 1YAUO 2VASA 2MWQA 3UNGC 4YL0A 1Q0DA 1D0XA 5L0JA 2Y39A 1A41A 1TKNA 3U0CA 5COFA 3L8IA 3GEEA 3N24A 4PR9A 2ETSA 1Q0MA 2ZD9A 1LVKA 3B71A 4MNDA 3SXYA 3MYIA 2XL6A 2R05A 3GM1A 2IYLD 4N6CA 1KTMA 4M63A 1D0YA 2J46A 4CIPA 3ABMC 4MW8A 2HSQA 2OKUA 3C8GB 5T3TA 4PJMA 1OW6A 1E84A 3KH2A 1TR2A 1NLXA 2YKZA 3ASNC 2V26A 3JRTA 4IAQA 1LI7A 3MX3A 1EI7A 1A7EA 4LLCA 4NCQA 5D91A 4U5GA 3NKDA 3DJUB 3ZTMA 1T6UA 2PFDA 4RD9A 2L9JA 3T9OA 3AQCA 5JVEA 2R02A 5A69A 1EQ1A 3K1IC 4YN0B 3JSZA 2DI3A 3EZIA 3QW0A 2L7AA 1SMYF 4K0DA 4XEVA 2NPUA 3QVZA 4CS7A 3H2UA 5L0GA 5L0FA 3EFOA 2HV6A 4CSAA 2CNWA 3TULA 1VYIA 2MHRA 1TWAA 2L81A 3EGDA 2R7UA 4U5FE 1VLTA 4P9TA 2WZGA 2HMZA 4OD4A 2F22A 1YJGA 3IEEA 4HFKB 2J0WA 5KYNA 2MYSA 4EIYA 1O87A 5BUOA 1BR1A 3MYFA 4CS8C 4E0IA 3ABLC 4GQHA 4CS9C 4I3MA 3KYJA 4QI0A 4JRZA 1QLEC 2I15A 3LUTB 4FAPB 1E2XA 4MVUA 2IM8A 3KKBA 1YARO 2QTVA 2R7RA 2GDCA 3HLZA 2XRHA 2H7VC 4DRJB 1Q0FA 2PBEA 3NG1A 4HE8D 4R32A 2EPOA 3R2PA 3TOLA 4FESA 3WODF 4YJWA 2HFIA 4JJGA 3PCVA 4O6MA 3FHDA 3S27A 2VB6A 2W4MA 4BEMJ 2H7BA 2WVOA 3U8VA 4EUKB 4YT2A 1C17M 2OQMA 3C8ZA 4J32B 4CS9A 3GORA 1NFNA 1MQVA 5DQTA 4MVMA 3AGTA 1D1AA 5L3VA 4EKWA 3EFOB 5KYWA 4MTFA 3K1IA 1GGQA 3LLKA 3EGDB 3RQEA 2OJED 4IJJA 4Z9JA 1PD1A 1OCZC 5JLIA 1LKXA 4NQFA 2Q9CA 1MMGA 2AWCA 2PX0A 1SF8A 2HZ8A 3B9QA 1WATA 1TWHA 2J9UA 3ZQYA 2TMVP 4U5CE 1AVOB 1Y6DA 1FAPB 2IOQA 4XEFA 1CGME 3M4BA 3M79A 4MTGA 2R7TA 1VTMP 3HJCA 4WJ0A 3CSKA 5D92A 3TJ5A 1A0BA 1RKEA 5BQIA 1CGNA 2ZPAA 2EIJC 2YVKA 1MNDA 1C02A 2Q9AA 1PV3A 2YL0A 3FAPB 3SXKA 2W45A 2UUHA 2HUJA 2KGOA 5JSLA 4HFFB 3T6GB 3UMIA 4CS8A 1HMDA 1NU7D 4A4AA 1JMWA 4JJFA 1ZHTA 3M1CB 2Q7RA 5EK0A 2GFHA 4EBJA 1DOWA 4MQ9F 5A6BD 3EHNA 3RQGA 3W2VA 1JPJA 2PP4A 2R9RB 3EQLF 3L1MA 3OEOA 4J30B 2EPNA 4NTAA 1OKKD 2J45A 1QVXA 5CI8A 4JCZA 1AEPA 3US6A 4E0HA 2WVQA 3C62A 3K7DA 3MLGA 4C7OA 3LEOA 3ZIBA 2AVKA 1ZU5A 1Q0KA 3IQTA 1W2WA 4KBLA 4BJTA 2R7QA 5KYWB 1H7IA 4XLNF 4G7ZF 2W4BA 3HTKC 1HE1A 4JC7A 1PD0A 2IXOA 2BE5F 1OXKA 2KYHA 3KMIA 4CBEA 3EH2A 1I4YA 1MMDA 3HNKA 3JYHA 3RVZA 3SP1A 1Z3IX 4AE4B 2XLOA 1T9KA 5AC4A 2E87A 3SXZA 3S29A 4ONSA 2XM4A 4JTDB 5B3SC 2KNHA 1RMVA 3FAJA 3VM6A 4EBBA 4O6NA 2LD6A 4XTKA 3I5PA 1ORSC 1RKEB 2YHSA 4D4NA 4UDVA 1OCOC 3NMKA 3LESA 1KNYA 4K7BA 3JSEO 2XXAA 1GQAA 2IXNA 3H65A 1QSPA 4U5DE 4IRUA 3DJNB 4MVSA 3L8JA 1NBBA 2B0HA 4PJNA 5A6KA 3I5QA 4OIRF 3POVA 1SYQA 1H9GA 3IHUA 1YZAA 4BJ5C 2P61A 3RIPA 1WGWA 3GWNA 2EIKC 5BQHA 2PX3A 5A6AA 1D0ZA 1WTYA 5K0IA 2J7PD 1OKKA 3CZ6A 3EPVA 3KYIA 4IARA 4WGZA 4QI2A 2IXPA 4JZAA 2VC9A 2XL4A 2HMQA 1RJ9A 2Y3DA 5KYYA 1OW8A 2XLEA 4P9FA 3S28A 3B29A 3K1HA 256BA 1G4US 5EHHA 4XPXA 4CIHA 2CYDA 2A6HF 2VH3A 3DKAA 4FX5A 4JEBA 5FZTA 5KYXB 3LS0A 3WHNA 3DZAA 2QY9A 2AP3A 5BQGA 2Z15A 3NMJA 2OG2A 4OIQF 1RXQA 3C63A 3RQFA 4AL0A 2AU5A 1RCPA 4YWQA 4CDYA 1LE4A 3DD7A 4G0HA 1F1MA 4OD5A 5B1BC 2XS8A 1ZW3A 2WVNA 2V3CC 2OU6A 2AWYA 2JPUA 1T5OA 2WZLA 3AOUA 4L6RA 2UUIA 4P6IC 4J7TA 3ZSUA 3GANA 2XXAB 5L0IA 4MVQA 5DLJA 4I1MA 1E86A 1FMVA 3L0IA 4OINF 2NG1A 3ABKC 1LS4A 3K6BA 1Q0GA 1GS9A 1JAFA 3AQBA 3ZC4A 3RF3A 2ICWG 2J9VA 2O9XA 1LE2A 3W2WA 2YL7A 2KJGA 4BG0A 1AUEA 3TOMA 3HKKA 3JCUQ 2Q3TA 2R7OA 4CX9A 1K04A 2JD3A 2R7XA 2HJ3A 4ER9A 1FFHA 1NU9C 3RFYA 3DI5A 2C03A 3N2ZB 4U5EE 4YT4A 1RJ9B 2WL8A 4BJ5A 2EINC 5F5HA 1G8XA 4Z9HA 1LS1A 2LK4A 3I4UA 1XZPA 4LDRA 5KYUA 3MFNA 2R7SA 3IQ6A 4E7SA 4FWVA 3S0XA 2R03A 1ORJA 4E18A 1LM3B 4I44A 2EPMX 1VOMA 1Z6AA 5L0DA 3M15A 3SXMA 3AG2C 1UG7A 1M56C 3HNIA 4H4KC 4C3BA 4JVSA 2G3KA 1FTSA 1DOVA 1M6TA 4KNVA 2LSEA 4WGYA 1I4ZA 4QDLA 3UGOA 4NY3A 2YLDA 5E3CA 2YL1A 1YA7O 1ZYRF 5E33A 3VF0A 5EGYA 2Q4FA 1FNTc 2QUPA 3SEOA 2WB7A 3U9JA 2XLWA 4MW3A 2H7OA 3KL4A 3M4CA 1NZEA 1XWJA 5DS5A 5COGA 3PDMP 1FR0A 3FOPA 3VAYA 1J8MF 3W8IA 3X1OA 2XL8A 1A7VA 2XLDA 3HNLA 1V74B 2KW3C 4CDVA 2A69F 1ST6A 1MMAA 3FOOA 4XLPF 3O55A 1FMWA 4ZLDA 3U3BA 4BEJA 4NTBA 1VK5A 4LERA 2QNLA 3EG9A 3NRHA 3V5XA 2XS1A 1S05A 3DAGA 3NMIA 4LLEA 4DRIB 2NUPA 4Q4ZF 2M4EA 1T01A 1OCRC 4PJLA 3A11A 1ZHZA 3HNJA 2DYSC 2D4UA 3DE9A 5L0HA 1YDIA 1CPRA 3V7OA 5F5FA 1NG1A 5KYUB 4YK5A 3RW0A 5F28E 1Z63A 2R7VA 2CGEA 5FCLA 3NKEA 3GEHA 3S84A 1PCXA 1ZHYA 3JZ0A 4JURI 3QMKA 2NSFA 3RYLA 4Q7CA 3TK0A 1G5ZA 2IXMA 2A68F 1EKYA 5AGFA 1A7DA 3GWLA 3Q6MA 2NSGA 3RH3A 1D1CA 1JRAA 3S9OA 1QZXA 3U2LA 4DRHB 1VB5A 3VRCA 2VCBA 5JS5A 1B68A 3LLIA 3CAXA 2YQYA 4BJ1A 1CGOA 2XM0A 1LPEA 2W9YA 2M64A 2ASRA 1MNEA 1VYKA 2XSEA 4IGGA 2X51A 3ZDLA 1K40A 2CW0F 3Q7LA 1JR8A 3O10A 3G4XA 2FFHA 4KNWA 4XWJA 4CJGA 1S7ZA 2CDQA 2L6GA 3C7JA 3NYMA 3UR3C 1HY5A 1O5HA 3QVYA 4NTFA 4O79A 4WABA 4Z9IA 3EG9B 3EH1A 2ZXRA 3U5SA 2QLAA 5DQZA 4BPMA 2H8AA 2YEVA 1SR2A 3F46A 2NUPB 3MBGA 3LJBA 1WN0A 2P6VA 4JKVA 3ZWIA 4DBRA 1XZQA 5A6JA 1MMNA 3NYLA 3U8PA 4G7OF 1KU2A 2XLVA 3AG4C 2VCAA 2FGYA 3S90A 1T6IA 1OCCC 2VCCA 4IWBA 5JUAA 5A6BA 4KI2A 2P1AA 1E85A 3SNHA 2CNWD 2Y3GA 4A2NB 4B6IA 4YT8A 1V55C 5JT4A 3FVYA 4DVYP 3SYNA 2A0BA 3T4RA 3GEIA 1ZHXA 3TD7A 1HW1A 1M2VA 3C18A 1V4AA 1VLSA 3ATPA 2G62A 4ULWA 5DS6A 1TFKB 3DAFA 1OR2A 2OOCA 2J8WA 3WAQA 3TJ6A 4EHPA 3CEXA 4AL1A 2X0CA 1EA8A 4JE9A 5HSWA 3ZQVA 2CCYA 3ZTZA 2BL2A 2PF4E 1M2OA 4GEHA 4PFOA 4CDAA 2DB4A 3DWWA 1H6GA 1ORYA 4YL1A 1HMOA 3BRJA 3DXJF 1T6QA 1Y4CA 1G4WR 2HS5A 2Y69C 2L6FA 1Z5ZA 3ITFA 3KPHA 1TFOB 4G78A 2HJMA 2XLHA 4YT5A 5T3WA 4EWCA 5B3IA 4PFPA 4OIOF 2YWAA 1OXBA 3IQ5A 4HEAJ 4U9DA 4IB4A 4NC3A 5T1DB 4DBQA 5IY5C 1K05A 3PHF2 3RKOF 3OA1A 3W8HA 2LQGA 3ZVRA 2QE9A 3JT1A 4ZLCA 4BJ6C 2YRFA 4MVZA 4AX2A 1IW7F 1UFBA 5TJ5E 1H9TA 1BZ4A 3EHMA 4Q5SF 3X2QC 4IAOA 4AK9A 2ZXWC 4GYTA 2J7PA 1M2VB 3A9CA 4K1OA 1VMAA 3WG7C 3FDQA 5KYYB 3IQCA 2IBFA 2OEXA 4PK4A 4G7HF 2EPKX 4C3EA 2G3VA 3BEHA 3QTHA 1WASA 3U3FA 1GM5A 1IZMA 3UGPA 2R25A 2DGJA 1M57C 1QQ3A 2JX0A 1QKRA 2J9WA 2XLMA 4JCHA 1E83A 3ZG1A 5L0CA 3LNRA 3EGXA 3LNMB 2NUTA 1WOLA 3G4ZA 3JYYA 4O7GA 2L6HA 3LAYA 5HV9A 2J9BA 5CI9A 2KSFA 3E9VA 3CQZA 4U5BE 3SZRA 2R7WA 2EPLX 2LFFA 2D5RB 1RKCA 2A6EF 3AG1C 4MVOA 3QZCA 2Y3BA 1ZW2A 4MVRA 4PACA 4YL3A 3ASOC 4N6HA 3QW1A 1YZCA 2OEVA 1BR4A 3UMHA 2EILC 2C04A 1ZVZA 2GAQA 1TWCA 3C8GD 3JTLO 3E70C 3N0TA 2DYRC 4RBNA 3GM3A 1U89A 3DM5A 3PMRA 4D4XA 1N1CA 1OR3A 2B0JA 1CPQA 2BC5A 3DE8A 3W4YA 1L3PA 3AJMA 3OWTA 4N06A 4U5HA 5AC5A 3GM2A 4W8KA 5L3QA 2YLIA 3DMDA 4N4WA 1OW7A 4DXWA 1R5ID 2J0XA 1TQGA 2RSEB 2LCHA 2PNOA 4X0RA 4I1OB 2LFDA 2Y3HA 1BR2A 1U0BB 4LDQA 4RDAA 4BJ6A 1ZU4A 1OQCA 1JPNA 1BBHA 2P7VA 4ULVA 1BDJB 4PJJA 4O6YA 1V54C 4C3DA 5CIVA 3U2MA 4JW1A 2LIGA 3J06A 1I5NA 3R7CA 4MS2A 4H54A 2WZFA 3EGXB 3B0UX
chains in the Genus database with same CATH topology
4JC7A 3PCVA 3DWWA 5BQIA 4NTBA 4YL1A 5BQHA 4J7YA 5K0IA 2UUIA 2UUHA 4J7TA 2Q7RA 2PNOA 3B29A 4JRZA 4NTAA 4YK5A 4JCZA 4WABA 4NTFA 3HKKA 4YL0A 4BPMA 5HV9A 5BQGA 4AL1A 2H8AA 3LEOA 4YL3A 4AL0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JC7 A;  3PCV A;  3DWW A;  5BQI A;  4NTB A;  4YL1 A;  5BQH A;  4J7Y A;  5K0I A;  2UUI A;  2UUH A;  4J7T A;  2Q7R A;  2PNO A;  3B29 A;  4JRZ A;  4NTA A;  4YK5 A;  4JCZ A;  4WAB A;  4NTF A;  3HKK A;  4YL0 A;  4BPM A;  5HV9 A;  5BQG A;  4AL1 A;  2H8A A;  3LEO A;  4YL3 A;  4AL0 A; 
#chains in the Genus database with same CATH topology
 3AG3 C;  1L7C A;  2NUT B;  2KQ9 A;  4ANJ A;  2A0U A;  3K33 A;  1APC A;  2FAP B;  3EZH A;  4J7Y A;  1Z23 A;  2OJQ A;  2HSB A;  3AGU A;  1LIH A;  2GWW A;  1YYJ A;  3B0V C;  3VYW A;  2OCC C;  4XQ1 A;  1YVI A;  1JOG A;  3JRM O;  4C7O B;  4EBK A;  4XEK A;  3U9M A;  4KC9 A;  1YYX A;  3FMS A;  5JP7 A;  3G50 A;  4JIO A;  4JTC B;  2KC3 A;  4DJ9 A;  4JTA B;  1R4T A;  2YZS A;  4W8P A;  4XPW A;  2EIM C;  3C8G A;  3LS1 A;  3Q7G A;  5DVW A;  2A1D D;  4E7Z A;  4CJO A;  3TQO A;  5E3A A;  3GOD A;  4AE4 A;  1QPU A;  3RVY A;  1C03 A;  1FFT C;  1D1B A;  2KK1 A;  2P0N A;  3H2V A;  3T6J A;  3T6B A;  1HE9 A;  3O39 A;  5GPG B;  3NDB B;  1LI5 A;  3V5Z A;  1TWG A;  2YL3 A;  5E2Q A;  5COM A;  4MTO A;  1Z7Q c;  4CSA C;  3Q6N A;  1SZI A;  1ZZP A;  4E17 A;  1O3U A;  3K66 A;  5KYX A;  3UMK A;  1NFO A;  1ZHW A;  2YLG A;  2HKV A;  1NSG B;  2HV7 A;  2ZXP A;  3EJN A;  3LEV A;  3F47 A;  2RD9 A;  4U9E A;  4DOZ A;  3ECS A;  1U6H A;  4F4B A;  3L34 A;  1WWP A;  3NYJ A;  2Q9B A;  5B1A C;  4DVZ A;  5JRA A;  2GA0 A;  1YA9 A;  1YLM A;  4LAC B;  3B0P A;  3IPM O;  2ZXO A;  4JEA A;  1J8Y F;  2I8B A;  2Q00 A;  3DM9 B;  3FXH A;  5DS4 A;  4OIP F;  3O6X A;  1HW2 A;  3V5Y A;  4LDK A;  2LP4 A;  4XPY A;  1YAU O;  2VAS A;  2MWQ A;  3UNG C;  4YL0 A;  1Q0D A;  1D0X A;  5L0J A;  2Y39 A;  1A41 A;  1TKN A;  3U0C A;  5COF A;  3L8I A;  3GEE A;  3N24 A;  4PR9 A;  2ETS A;  1Q0M A;  2ZD9 A;  1LVK A;  3B71 A;  4MND A;  3SXY A;  3MYI A;  2XL6 A;  2R05 A;  3GM1 A;  2IYL D;  4N6C A;  1KTM A;  4M63 A;  1D0Y A;  2J46 A;  4CIP A;  3ABM C;  4MW8 A;  2HSQ A;  2OKU A;  3C8G B;  5T3T A;  4PJM A;  1OW6 A;  1E84 A;  3KH2 A;  1TR2 A;  1NLX A;  2YKZ A;  3ASN C;  2V26 A;  3JRT A;  4IAQ A;  1LI7 A;  3MX3 A;  1EI7 A;  1A7E A;  4LLC A;  4NCQ A;  5D91 A;  4U5G A;  3NKD A;  3DJU B;  3ZTM A;  1T6U A;  2PFD A;  4RD9 A;  2L9J A;  3T9O A;  3AQC A;  5JVE A;  2R02 A;  5A69 A;  1EQ1 A;  3K1I C;  4YN0 B;  3JSZ A;  2DI3 A;  3EZI A;  3QW0 A;  2L7A A;  1SMY F;  4K0D A;  4XEV A;  2NPU A;  3QVZ A;  4CS7 A;  3H2U A;  5L0G A;  5L0F A;  3EFO A;  2HV6 A;  4CSA A;  2CNW A;  3TUL A;  1VYI A;  2MHR A;  1TWA A;  2L81 A;  3EGD A;  2R7U A;  4U5F E;  1VLT A;  4P9T A;  2WZG A;  2HMZ A;  4OD4 A;  2F22 A;  1YJG A;  3IEE A;  4HFK B;  2J0W A;  5KYN A;  2MYS A;  4EIY A;  1O87 A;  5BUO A;  1BR1 A;  3MYF A;  4CS8 C;  4E0I A;  3ABL C;  4GQH A;  4CS9 C;  4I3M A;  3KYJ A;  4QI0 A;  4JRZ A;  1QLE C;  2I15 A;  3LUT B;  4FAP B;  1E2X A;  4MVU A;  2IM8 A;  3KKB A;  1YAR O;  2QTV A;  2R7R A;  2GDC A;  3HLZ A;  2XRH A;  2H7V C;  4DRJ B;  1Q0F A;  2PBE A;  3NG1 A;  4HE8 D;  4R32 A;  2EPO A;  3R2P A;  3TOL A;  4FES A;  3WOD F;  4YJW A;  2HFI A;  4JJG A;  3PCV A;  4O6M A;  3FHD A;  3S27 A;  2VB6 A;  2W4M A;  4BEM J;  2H7B A;  2WVO A;  3U8V A;  4EUK B;  4YT2 A;  1C17 M;  2OQM A;  3C8Z A;  4J32 B;  4CS9 A;  3GOR A;  1NFN A;  1MQV A;  5DQT A;  4MVM A;  3AGT A;  1D1A A;  5L3V A;  4EKW A;  3EFO B;  5KYW A;  4MTF A;  3K1I A;  1GGQ A;  3LLK A;  3EGD B;  3RQE A;  2OJE D;  4IJJ A;  4Z9J A;  1PD1 A;  1OCZ C;  5JLI A;  1LKX A;  4NQF A;  2Q9C A;  1MMG A;  2AWC A;  2PX0 A;  1SF8 A;  2HZ8 A;  3B9Q A;  1WAT A;  1TWH A;  2J9U A;  3ZQY A;  2TMV P;  4U5C E;  1AVO B;  1Y6D A;  1FAP B;  2IOQ A;  4XEF A;  1CGM E;  3M4B A;  3M79 A;  4MTG A;  2R7T A;  1VTM P;  3HJC A;  4WJ0 A;  3CSK A;  5D92 A;  3TJ5 A;  1A0B A;  1RKE A;  5BQI A;  1CGN A;  2ZPA A;  2EIJ C;  2YVK A;  1MND A;  1C02 A;  2Q9A A;  1PV3 A;  2YL0 A;  3FAP B;  3SXK A;  2W45 A;  2UUH A;  2HUJ A;  2KGO A;  5JSL A;  4HFF B;  3T6G B;  3UMI A;  4CS8 A;  1HMD A;  1NU7 D;  4A4A A;  1JMW A;  4JJF A;  1ZHT A;  3M1C B;  2Q7R A;  5EK0 A;  2GFH A;  4EBJ A;  1DOW A;  4MQ9 F;  5A6B D;  3EHN A;  3RQG A;  3W2V A;  1JPJ A;  2PP4 A;  2R9R B;  3EQL F;  3L1M A;  3OEO A;  4J30 B;  2EPN A;  4NTA A;  1OKK D;  2J45 A;  1QVX A;  5CI8 A;  4JCZ A;  1AEP A;  3US6 A;  4E0H A;  2WVQ A;  3C62 A;  3K7D A;  3MLG A;  4C7O A;  3LEO A;  3ZIB A;  2AVK A;  1ZU5 A;  1Q0K A;  3IQT A;  1W2W A;  4KBL A;  4BJT A;  2R7Q A;  5KYW B;  1H7I A;  4XLN F;  4G7Z F;  2W4B A;  3HTK C;  1HE1 A;  4JC7 A;  1PD0 A;  2IXO A;  2BE5 F;  1OXK A;  2KYH A;  3KMI A;  4CBE A;  3EH2 A;  1I4Y A;  1MMD A;  3HNK A;  3JYH A;  3RVZ A;  3SP1 A;  1Z3I X;  4AE4 B;  2XLO A;  1T9K A;  5AC4 A;  2E87 A;  3SXZ A;  3S29 A;  4ONS A;  2XM4 A;  4JTD B;  5B3S C;  2KNH A;  1RMV A;  3FAJ A;  3VM6 A;  4EBB A;  4O6N A;  2LD6 A;  4XTK A;  3I5P A;  1ORS C;  1RKE B;  2YHS A;  4D4N A;  4UDV A;  1OCO C;  3NMK A;  3LES A;  1KNY A;  4K7B A;  3JSE O;  2XXA A;  1GQA A;  2IXN A;  3H65 A;  1QSP A;  4U5D E;  4IRU A;  3DJN B;  4MVS A;  3L8J A;  1NBB A;  2B0H A;  4PJN A;  5A6K A;  3I5Q A;  4OIR F;  3POV A;  1SYQ A;  1H9G A;  3IHU A;  1YZA A;  4BJ5 C;  2P61 A;  3RIP A;  1WGW A;  3GWN A;  2EIK C;  5BQH A;  2PX3 A;  5A6A A;  1D0Z A;  1WTY A;  5K0I A;  2J7P D;  1OKK A;  3CZ6 A;  3EPV A;  3KYI A;  4IAR A;  4WGZ A;  4QI2 A;  2IXP A;  4JZA A;  2VC9 A;  2XL4 A;  2HMQ A;  1RJ9 A;  2Y3D A;  5KYY A;  1OW8 A;  2XLE A;  4P9F A;  3S28 A;  3B29 A;  3K1H A;  256B A;  1G4U S;  5EHH A;  4XPX A;  4CIH A;  2CYD A;  2A6H F;  2VH3 A;  3DKA A;  4FX5 A;  4JEB A;  5FZT A;  5KYX B;  3LS0 A;  3WHN A;  3DZA A;  2QY9 A;  2AP3 A;  5BQG A;  2Z15 A;  3NMJ A;  2OG2 A;  4OIQ F;  1RXQ A;  3C63 A;  3RQF A;  4AL0 A;  2AU5 A;  1RCP A;  4YWQ A;  4CDY A;  1LE4 A;  3DD7 A;  4G0H A;  1F1M A;  4OD5 A;  5B1B C;  2XS8 A;  1ZW3 A;  2WVN A;  2V3C C;  2OU6 A;  2AWY A;  2JPU A;  1T5O A;  2WZL A;  3AOU A;  4L6R A;  2UUI A;  4P6I C;  4J7T A;  3ZSU A;  3GAN A;  2XXA B;  5L0I A;  4MVQ A;  5DLJ A;  4I1M A;  1E86 A;  1FMV A;  3L0I A;  4OIN F;  2NG1 A;  3ABK C;  1LS4 A;  3K6B A;  1Q0G A;  1GS9 A;  1JAF A;  3AQB A;  3ZC4 A;  3RF3 A;  2ICW G;  2J9V A;  2O9X A;  1LE2 A;  3W2W A;  2YL7 A;  2KJG A;  4BG0 A;  1AUE A;  3TOM A;  3HKK A;  3JCU Q;  2Q3T A;  2R7O A;  4CX9 A;  1K04 A;  2JD3 A;  2R7X A;  2HJ3 A;  4ER9 A;  1FFH A;  1NU9 C;  3RFY A;  3DI5 A;  2C03 A;  3N2Z B;  4U5E E;  4YT4 A;  1RJ9 B;  2WL8 A;  4BJ5 A;  2EIN C;  5F5H A;  1G8X A;  4Z9H A;  1LS1 A;  2LK4 A;  3I4U A;  1XZP A;  4LDR A;  5KYU A;  3MFN A;  2R7S A;  3IQ6 A;  4E7S A;  4FWV A;  3S0X A;  2R03 A;  1ORJ A;  4E18 A;  1LM3 B;  4I44 A;  2EPM X;  1VOM A;  1Z6A A;  5L0D A;  3M15 A;  3SXM A;  3AG2 C;  1UG7 A;  1M56 C;  3HNI A;  4H4K C;  4C3B A;  4JVS A;  2G3K A;  1FTS A;  1DOV A;  1M6T A;  4KNV A;  2LSE A;  4WGY A;  1I4Z A;  4QDL A;  3UGO A;  4NY3 A;  2YLD A;  5E3C A;  2YL1 A;  1YA7 O;  1ZYR F;  5E33 A;  3VF0 A;  5EGY A;  2Q4F A;  1FNT c;  2QUP A;  3SEO A;  2WB7 A;  3U9J A;  2XLW A;  4MW3 A;  2H7O A;  3KL4 A;  3M4C A;  1NZE A;  1XWJ A;  5DS5 A;  5COG A;  3PDM P;  1FR0 A;  3FOP A;  3VAY A;  1J8M F;  3W8I A;  3X1O A;  2XL8 A;  1A7V A;  2XLD A;  3HNL A;  1V74 B;  2KW3 C;  4CDV A;  2A69 F;  1ST6 A;  1MMA A;  3FOO A;  4XLP F;  3O55 A;  1FMW A;  4ZLD A;  3U3B A;  4BEJ A;  4NTB A;  1VK5 A;  4LER A;  2QNL A;  3EG9 A;  3NRH A;  3V5X A;  2XS1 A;  1S05 A;  3DAG A;  3NMI A;  4LLE A;  4DRI B;  2NUP A;  4Q4Z F;  2M4E A;  1T01 A;  1OCR C;  4PJL A;  3A11 A;  1ZHZ A;  3HNJ A;  2DYS C;  2D4U A;  3DE9 A;  5L0H A;  1YDI A;  1CPR A;  3V7O A;  5F5F A;  1NG1 A;  5KYU B;  4YK5 A;  3RW0 A;  5F28 E;  1Z63 A;  2R7V A;  2CGE A;  5FCL A;  3NKE A;  3GEH A;  3S84 A;  1PCX A;  1ZHY A;  3JZ0 A;  4JUR I;  3QMK A;  2NSF A;  3RYL A;  4Q7C A;  3TK0 A;  1G5Z A;  2IXM A;  2A68 F;  1EKY A;  5AGF A;  1A7D A;  3GWL A;  3Q6M A;  2NSG A;  3RH3 A;  1D1C A;  1JRA A;  3S9O A;  1QZX A;  3U2L A;  4DRH B;  1VB5 A;  3VRC A;  2VCB A;  5JS5 A;  1B68 A;  3LLI A;  3CAX A;  2YQY A;  4BJ1 A;  1CGO A;  2XM0 A;  1LPE A;  2W9Y A;  2M64 A;  2ASR A;  1MNE A;  1VYK A;  2XSE A;  4IGG A;  2X51 A;  3ZDL A;  1K40 A;  2CW0 F;  3Q7L A;  1JR8 A;  3O10 A;  3G4X A;  2FFH A;  4KNW A;  4XWJ A;  4CJG A;  1S7Z A;  2CDQ A;  2L6G A;  3C7J A;  3NYM A;  3UR3 C;  1HY5 A;  1O5H A;  3QVY A;  4NTF A;  4O79 A;  4WAB A;  4Z9I A;  3EG9 B;  3EH1 A;  2ZXR A;  3U5S A;  2QLA A;  5DQZ A;  4BPM A;  2H8A A;  2YEV A;  1SR2 A;  3F46 A;  2NUP B;  3MBG A;  3LJB A;  1WN0 A;  2P6V A;  4JKV A;  3ZWI A;  4DBR A;  1XZQ A;  5A6J A;  1MMN A;  3NYL A;  3U8P A;  4G7O F;  1KU2 A;  2XLV A;  3AG4 C;  2VCA A;  2FGY A;  3S90 A;  1T6I A;  1OCC C;  2VCC A;  4IWB A;  5JUA A;  5A6B A;  4KI2 A;  2P1A A;  1E85 A;  3SNH A;  2CNW D;  2Y3G A;  4A2N B;  4B6I A;  4YT8 A;  1V55 C;  5JT4 A;  3FVY A;  4DVY P;  3SYN A;  2A0B A;  3T4R A;  3GEI A;  1ZHX A;  3TD7 A;  1HW1 A;  1M2V A;  3C18 A;  1V4A A;  1VLS A;  3ATP A;  2G62 A;  4ULW A;  5DS6 A;  1TFK B;  3DAF A;  1OR2 A;  2OOC A;  2J8W A;  3WAQ A;  3TJ6 A;  4EHP A;  3CEX A;  4AL1 A;  2X0C A;  1EA8 A;  4JE9 A;  5HSW A;  3ZQV A;  2CCY A;  3ZTZ A;  2BL2 A;  2PF4 E;  1M2O A;  4GEH A;  4PFO A;  4CDA A;  2DB4 A;  3DWW A;  1H6G A;  1ORY A;  4YL1 A;  1HMO A;  3BRJ A;  3DXJ F;  1T6Q A;  1Y4C A;  1G4W R;  2HS5 A;  2Y69 C;  2L6F A;  1Z5Z A;  3ITF A;  3KPH A;  1TFO B;  4G78 A;  2HJM A;  2XLH A;  4YT5 A;  5T3W A;  4EWC A;  5B3I A;  4PFP A;  4OIO F;  2YWA A;  1OXB A;  3IQ5 A;  4HEA J;  4U9D A;  4IB4 A;  4NC3 A;  5T1D B;  4DBQ A;  5IY5 C;  1K05 A;  3PHF 2;  3RKO F;  3OA1 A;  3W8H A;  2LQG A;  3ZVR A;  2QE9 A;  3JT1 A;  4ZLC A;  4BJ6 C;  2YRF A;  4MVZ A;  4AX2 A;  1IW7 F;  1UFB A;  5TJ5 E;  1H9T A;  1BZ4 A;  3EHM A;  4Q5S F;  3X2Q C;  4IAO A;  4AK9 A;  2ZXW C;  4GYT A;  2J7P A;  1M2V B;  3A9C A;  4K1O A;  1VMA A;  3WG7 C;  3FDQ A;  5KYY B;  3IQC A;  2IBF A;  2OEX A;  4PK4 A;  4G7H F;  2EPK X;  4C3E A;  2G3V A;  3BEH A;  3QTH A;  1WAS A;  3U3F A;  1GM5 A;  1IZM A;  3UGP A;  2R25 A;  2DGJ A;  1M57 C;  1QQ3 A;  2JX0 A;  1QKR A;  2J9W A;  2XLM A;  4JCH A;  1E83 A;  3ZG1 A;  5L0C A;  3LNR A;  3EGX A;  3LNM B;  2NUT A;  1WOL A;  3G4Z A;  3JYY A;  4O7G A;  2L6H A;  3LAY A;  5HV9 A;  2J9B A;  5CI9 A;  2KSF A;  3E9V A;  3CQZ A;  4U5B E;  3SZR A;  2R7W A;  2EPL X;  2LFF A;  2D5R B;  1RKC A;  2A6E F;  3AG1 C;  4MVO A;  3QZC A;  2Y3B A;  1ZW2 A;  4MVR A;  4PAC A;  4YL3 A;  3ASO C;  4N6H A;  3QW1 A;  1YZC A;  2OEV A;  1BR4 A;  3UMH A;  2EIL C;  2C04 A;  1ZVZ A;  2GAQ A;  1TWC A;  3C8G D;  3JTL O;  3E70 C;  3N0T A;  2DYR C;  4RBN A;  3GM3 A;  1U89 A;  3DM5 A;  3PMR A;  4D4X A;  1N1C A;  1OR3 A;  2B0J A;  1CPQ A;  2BC5 A;  3DE8 A;  3W4Y A;  1L3P A;  3AJM A;  3OWT A;  4N06 A;  4U5H A;  5AC5 A;  3GM2 A;  4W8K A;  5L3Q A;  2YLI A;  3DMD A;  4N4W A;  1OW7 A;  4DXW A;  1R5I D;  2J0X A;  1TQG A;  2RSE B;  2LCH A;  2PNO A;  4X0R A;  4I1O B;  2LFD A;  2Y3H A;  1BR2 A;  1U0B B;  4LDQ A;  4RDA A;  4BJ6 A;  1ZU4 A;  1OQC A;  1JPN A;  1BBH A;  2P7V A;  4ULV A;  1BDJ B;  4PJJ A;  4O6Y A;  1V54 C;  4C3D A;  5CIV A;  3U2M A;  4JW1 A;  2LIG A;  3J06 A;  1I5N A;  3R7C A;  4MS2 A;  4H54 A;  2WZF A;  3EGX B;  3B0U X; 
#chains in the Genus database with same CATH homology
 4JC7 A;  3PCV A;  3DWW A;  5BQI A;  4NTB A;  4YL1 A;  5BQH A;  4J7Y A;  5K0I A;  2UUI A;  2UUH A;  4J7T A;  2Q7R A;  2PNO A;  3B29 A;  4JRZ A;  4NTA A;  4YK5 A;  4JCZ A;  4WAB A;  4NTF A;  3HKK A;  4YL0 A;  4BPM A;  5HV9 A;  5BQG A;  4AL1 A;  2H8A A;  3LEO A;  4YL3 A;  4AL0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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