4NZVA

Dna double-strand break repair pathway choice is directed by distinct mre11 nuclease activities
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
329
structure length
329
Chain Sequence
HHHHHVINLKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGNHDWKGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPDESEALRKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAGYAGIEQGREIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNFPGYVRVVYEEDSGILPDLMGEIDNLVKIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities.
pubmed doi rcsb
molecule tags Hydrolase
source organism Thermotoga maritima
molecule keywords Exonuclease, putative
total genus 110
structure length 329
sequence length 329
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-12-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.160.210 Alpha Beta 2-Layer Sandwich Double Stranded RNA Binding Domain DNA double-strand break repair nuclease 4nzvA02
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 4nzvA01
4ZVZA 4DHLA 1NNWA 2CV9A 2HY1A 2NPPC 2O8GA 3K7WC 3C5WC 3QFOA 3THNA 4MP0A 5EQVA 4H2IA 1S95A 1AUIA 5J28A 3DSCA 3C9FA 2WDEA 2GJUA 4UT3A 3IB7A 5GTUA 4UT2A 2O8AA 4ORCA 4F0ZA 2USHA 2QFRA 3EGGA 1S3MA 5IOHA 1OIDA 4H2FA 4UT3B 1TCOA 2WDFA 4V0VA 3IB8A 2JOGA 3RL5A 1FJMA 3H62B 1USHA 4FBQA 2A22A 5F3WA 2HYOA 4FBKA 4ZX2A 3AUZA 4O24A 1SU1A 3FGAC 3QFNA 4H2BA 4I5LC 3H61A 4H1SA 1KBPA 1QFCA 4M0VA 5JPEA 4TUGA 2WDCA 1T71A 3RL3A 3HVQA 3RQZA 2NXFA 2IE4C 4HD0A 2IE3C 4LTYA 4IL1A 1Z2WA 1WARA 1XZWA 1HO5A 3H63A 3T1IA 3N5UA 3TGHA 4JA9A 4V0XA 3PSNA 2P6BA 2BCDA 1W24A 3E7BA 4V0WA 3AV0A 2IAEC 4KKZA 1MF8A 3DW8C 3EGHA 3RL4A 5HPEA 3ZTVA 3GVEA 2QFPA 4FCXA 2NYMC 2HYPA 3ICFA 3PSOA 1HP1A 2Z1AA 4XPNA 5B8IA 3QFMA 1Z2XA 4IYPC 3QFKA 4H1YP 4ORBA 1OIEA 2NYLC 1S3LA 2Z72A 4FBWA 4NZVA 3IVEA 3H67A 1U32A 1S3NA 4MOVA 3THOB 4O4KA 3V4YA 4YKEA 4G9JA 1XM7A 4B2OA 3QG5C 2DFJA 2QJCA 2WDDA 4KBPA 3H60A 1M63A 2BDXA 2YVTA 2KKNA 5JJTA 1II7A 3E7AA 5JPFA 3ZU0A 1S70A 3H69A 3P71C 4O43A 2ZBMA 5DNYA 4UWQA 3K7VC 2Q8UA 4TUIA 1JK7A 3IVDA 5C1VA 1UTEA 3H64A 1QHWA 1G5BA 2XMOA 1S8EA 4LU9A 1HPUA 2Z06A 4WWLA 4O5GA 3LL8A 1WAO1 4I5NC 4LACC 4ORAA 4Q7FA 1V73A 2R17A 2BQ8X 3CK2A 3DSDA 4DSYA 4JA7A 2AHDA 4J6OA 4H2GA 3H68A 4DT2A 3H66A 4MOYA 1OI8A 3KBPA 4OR9A 1UF3A 3JYFA 1T70A 1IT6A 5INBA
chains in the Genus database with same CATH superfamily
2HY1A 2UU9E 5KL7A 2LCEA 4BCAA 3QFOA 2E5LE 4M2ZA 2LUQA 2NABA 2EN3A 1AUIA 2EPLX 2EL4A 1HR0E 3DSCA 3H09A 3ZOQB 5AE3A 3C9FA 2EPUA 2VRDA 3E0JA 5GTUA 2VF1A 3VK6A 4WX9A 2JPAA 2LVHA 4BC9A 2EP3A 2USHA 1J5EE 1O0WA 4DV0E 3EGGA 1X49A 2EE8A 3IB8A 4F2JC 3RL5A 2WZOA 4M30A 3BF2A 1B69A 1PKPA 4RHBB 1FKAE 1FJMA 2EN2A 1X6FA 4FBKA 4B3TE 4ZX2A 3F6HA 2EPMX 5LL6R 2WCC3 1SU1A 3QFNA 2BBGA 4DMIA 3H61A 2CT1A 1N36E 1HNXE 4DKKA 5JPEA 1XNRE 2B7TA 4JV5E 3LMLA 2HHHE 4DV3E 3HVQA 2UUCE 5A6BA 3IWCA 1A1IA 2EQ3A 3BBGA 3C6KA 2L2KB 3UK3C 1IMUA 1WARA 4JI6E 3T1IA 2D9HA 2YTOA 3N5UA 2YTGA 3MHSC 1MGTA 2CSHA 3PSNA 3VYXA 3OTOE 3RL4A 1QU6A 2EPXA 4R2QA 1IBLE 3J80C 2EMAA 4RH8A 1A1GA 5B8IA 3PSOA 4GZNC 4JI2E 4IYPC 4H1YP 4I8OA 4ORBA 2NYLC 2DB2A 5T6JA 4LF7E 2EOHA 2YT4A 4FBWA 3H67A 1U32A 2EMHA 3THOB 3K6QA 2RSIA 1GQEA 2ENAA 4KWYA 3T1YE 2I9IA 4DR7E 1IBME 2MDGA 2VQFE 2RPCA 2KKNA 2UXDE 1IQSA 3E7AA 5JPFA 4WPYA 2EOJA 2L2NA 5AC4A 4DR3E 3ZU0A 1S70A 5KL5A 3HPZA 3P71C 2R76A 2EN4A 2ZBMA 2EL6A 3F6GA 2ENCA 4TUIA 3M99B 2UUBE 1YFHA 4LF5E 1UTEA 1QHWA 2I13A 2J7JA 4O5GA 4Q35B 2EOQA 4I5NC 2YU8A 1V73A 2IHR1 2FV4B 1EKZA 2AHDA 1X5WA 4H2GA 3KWRA 3H66A 2EPOA 1T4NA 2YEQA 1OI8A 4MOYA 4GKJE 1EH7A 5A6BD 4N4RB 5IXMB 1IT6A 4ZVZA 4DHLA 2MC6A 1T38A 1WJPA 2WBSA 5TSEA 1UILA 4X62E 3C5WC 3THNA 4BHCA 1KYQA 2LMZA 1S95A 2V85A 2YSOA 2DMYA 2NA2A 4F6NA 3ADJA 4LFCE 5J28A 2JYAA 5LMNE 4UT3A 1RMDA 4X64E 2EMCA 4F0ZA 4DV2E 2YRKA 1S3MA 5IOHA 2M7QA 4DV6E 4F9BB 4V0VA 2ZO9B 2EOXA 5IV8B 2LT7A 2YTIA 1DGCA 3LLHA 5IT9C 3H62B 4IJDA 1DI2A 4LF8E 2A22A 2JR1A 4JI8E 1KJKA 3RMPA 2ZOAA 2B9DA 1YYOA 2LJHA 2EOEA 4OX9E 2VQEE 2NUEA 3HTXA 3AUZA 1YYKA 2E1MA 2PRTA 4LF4E 2LJUA 4H1SA 2LUPB 5AASA 4YHHE 4K0KE 4M0VA 2G7HA 2ZM6E 1T71A 3RQZA 2EOZA 2WBTA 1HNZE 1BBGA 2DGCA 4HD0A 4IL1A 1X6EA 1Z2WA 4JYAE 1ZR9A 1HO5A 1XZWA 2YRMA 4ZYEA 2M4IA 2V83A 4JA9A 2M1SA 3TGHA 2P6BA 1W24A 5BR8E 4NHRA 2EM8A 4KKZA 3DW8C 3HPSA 1A1KA 3J81C 2L2MA 2YTPA 3DJWA 4IS1C 3EQ1A 4KZSA 2EMKA 1AAYA 2DSYA 3D03A 4BHBA 3GVEA 2V89A 4FCXA 3ICFA 4XPNA 2Z1AA 1MEYC 3MSWA 4X65E 5LMUE 3QFMA 2EPZA 4DV1E 3QFKA 2HC5A 1RQ0A 1OIEA 2Z72A 1RC7A 1NEIA 2YWQA 2RSMA 2JOBA 2B7VA 4ZYDA 4BS9A 1WRJA 2EM6A 2V87A 2B3TB 4R2PA 2EM4A 1F2IG 1A1FA 4YKEA 2EMXA 2EM7A 1G2DC 4B2OA 3QG5C 2DFJA 2ELZA 2LO3A 1YUIA 2EMWA 2EN6A 2UXBE 5IWAE 3EPLA 2BDXA 2YVTA 4R03A 2L3CA 4OOGC 2WBUA 1II7A 4DUZE 3EPJA 4AQYE 2FGGA 2M9AA 2YTDA 4ZYHA 1P47A 1J26A 1TF6A 2L33A 1XMQE 1FJGE 3K7VC 1ZU1A 2L92A 2L6MA 2K4VA 4WFTA 2XMOA 5AC5A 2UUAE 1HPUA 4LACC 3LL8A 4ORAA 2YSPA 1T4OA 3C4BA 2A25A 4DSYA 5AE1A 3HQ1A 1BBOA 2V88A 4JI4E 2EM3A 4MP0A 5INBA 4DR5E 1PDAA 3EPKA 1NNWA 2NPPC 4R2SA 4R2AA 2O8GA 5A6AA 3K7WC 1UHZA 4H2IA 2EOSA 2YTEA 1YZ9A 4FK5C 4M9VC 1QNTA 3ECRA 2EQ1A 1IBKE 4X8WA 3MHHC 4LFBE 2GJUA 2WDEA 1ZBTA 3IB7A 4R8OA 4UT2A 2EPAA 2O8AA 1N32E 2CPNA 4BMJA 3OMLA 1GTKA 2KOUA 1A1JA 2CTDA 1EH6A 1OIDA 4F6MA 1YUJA 2ELYA 2LV2A 4H2FA 4LF6E 2ODRC 2WDFA 2EMIA 1IQOA 1GZ6A 2EM2A 1G2FC 4NXME 2EMLA 4DV5E 4FBQA 3P1XA 2EQ0A 2DXNA 3EPHA 2HYOA 2LE2A 2UXCE 2EPCA 4O24A 4I5LC 2EMZA 1KBPA 2ADRA 4X9JA 2KHXA 2L3JA 3VYYA 2EMGA 3RL3A 2JWOA 2ODRD 4DUYE 2NXFA 2IE4C 2IE3C 2YRHA 3BIDA 4JI5E 3H63A 1XNQE 4ZYGA 3T1HE 2GLIA 4V0XA 2K7IA 2IAEC 2BB8A 3J7AG 3IWBA 3EGHA 2E72A 2YTQA 4MLVA 5HPEA 1WXRA 3ZTVA 1X48A 2YZTA 4WSPA 4BC7A 1N33E 2LRSA 4Q28A 2R1FA 1T4LB 1NCSA 2DRPA 1SR9A 4J8ZA 2N3GA 1UBDC 3J7Yp 1S3LA 3IVEA 1TF3A 1L4SA 1S3NA 4WXCA 2EPRA 2EMYA 4O4KA 5KL3A 2JVAA 2DIXA 4MLQA 2YPNA 1XM7A 5CFFE 2QJCA 2WDDA 4LF9E 2EOOA 1WHNA 4KBPA 5A69A 2V86A 5JJTA 1XMOE 2EZ6A 3BGHA 2DXLA 1STUA 5A6KA 4JI3E 4O43A 2F8BA 2EOFA 2Q8UA 1JK7A 3IVDA 5C1VA 1N34E 2MC5A 2RTXA 2EN7A 1G5BA 3TQMA 2MDRA 4JI1E 3DF6A 4KHPE 4WWLA 1WAO1 4Q7FA 4X66E 3CK2A 4DR1E 2BQ8X 3C6MA 2VE7C 4JA7A 2HJJA 3ADGA 4J6OA 3ADLA 4B3ME 3H68A 1ZBQA 3KBPA 2LTSA 1T39A 1UF3A 3JYFA 2EWLA 2KONA 1T70A 1A1LA 2CV9A 3FLOA 4B3RE 2EM5A 5EQVA 2JP9A 2EN1A 2EMFA 2JXPA 3JU0A 1ZAAC 4R2DA 2DLKA 1X6HA 5KL4A 4JI0E 4WYQB 4YY3E 2V8QB 4ORCA 4JI7E 3JAMC 1YPNA 2QFRA 2NUGA 4L5NC 2GPIA 4UT3B 1PJSA 1TCOA 2DLQA 4DV4E 4HEIA 3ADIA 3KZYA 2JOGA 2EJ4A 2N3HA 3JTZA 5AE2A 1USHA 1PJTA 4R2EA 4GKKE 1YYWA 2RS6A 2ENHA 1Z1BA 2EPNA 3FGAC 4LFAE 4H2BA 2YTNA 1JK2A 5A2QC 5A6JA 4B3SE 1QFCA 1WHQA 5ADZA 1DQ3A 2WDCA 5KL6A 4BBYA 2YTFA 4LTYA 4R2CA 1BB8A 2EPPA 1LLMC 3FIGA 2BCDA 4V0WA 3E7BA 3AV0A 1MF8A 5FLXC 4R2RA 3C4TA 4NXNE 4F54A 1X47A 2QFPA 4P78A 4DR6E 2HYPA 2NYMC 1HP1A 1X3CA 4GEQB 1A1HA 2JY9A 1Z2XA 1AH5A 1N3GA 2EOMA 4NZVA 4DR4E 2L8TA 3L00A 4HTGA 4MOVA 3V4YA 2MKNA 2N8XA 3HXLA 2JOXA 2MKDA 4G9JA 2H36X 2RS7A 2EM0A 3KZZA 3H60A 1M63A 4F9CB 1YSAC 2EM9A 2YTJA 4DR2E 2GHFA 4DV7E 4WSGA 1I94E 2F4VE 2HGHA 2RQLA 3H69A 2NUFA 2LTRA 2EOIA 4F9AB 5KL2A 5DNYA 2EMBA 4UWQA 2DMIA 1EH8A 2EN8A 3H64A 1S8EA 4LU9A 4TUGA 2Z06A 1HNWE 2LBSB 4L8NA 2FTXB 2EL5A 1TN9A 2R17A 3DSDA 1SFEA 5LLQA 2YU5A 4DT2A 3VHTB 1UN6B 1PJQA 4WXDA 3IWDA 2EPKX 4OR9A 2EORA 2EOYA 4P7DA 1JK1A 5F3WA
chains in the Genus database with same CATH topology
4ZVZA 4DHLA 1NNWA 2CV9A 2HY1A 2NPPC 3FLOA 2O8GA 3K7WC 3C5WC 3QFOA 3THNA 4MP0A 5EQVA 4H2IA 1S95A 1AUIA 3DSCA 5J28A 3C9FA 2WDEA 2GJUA 3E0JA 3IB7A 4UT3A 5GTUA 4UT2A 2O8AA 4ORCA 4F0ZA 2USHA 2QFRA 3EGGA 1S3MA 5IOHA 1OIDA 4H2FA 4UT3B 1TCOA 2WDFA 4V0VA 3IB8A 2ZO9B 2JOGA 3RL5A 1FJMA 3H62B 1USHA 4FBQA 2A22A 5F3WA 2DXNA 2HYOA 4FBKA 2ZOAA 4ZX2A 3AUZA 4O24A 1SU1A 3FGAC 3QFNA 4H2BA 4I5LC 3H61A 4H1SA 1KBPA 1QFCA 4M0VA 5JPEA 4TUGA 2WDCA 1T71A 3RL3A 3HVQA 3RQZA 2NXFA 2IE4C 4HD0A 2IE3C 4LTYA 4IL1A 1Z2WA 1WARA 1XZWA 1HO5A 3H63A 3T1IA 3N5UA 3TGHA 4JA9A 4V0XA 3PSNA 2P6BA 2BCDA 1W24A 3E7BA 4V0WA 3AV0A 2IAEC 4KKZA 1MF8A 3DW8C 3EGHA 3RL4A 5HPEA 3ZTVA 3D03A 3GVEA 2QFPA 4FCXA 2NYMC 2HYPA 3ICFA 3PSOA 1HP1A 2Z1AA 4XPNA 5B8IA 3QFMA 1Z2XA 4IYPC 3QFKA 4H1YP 4ORBA 1OIEA 2NYLC 1S3LA 2Z72A 4FBWA 4NZVA 3IVEA 3H67A 1U32A 1S3NA 4MOVA 3THOB 4O4KA 3V4YA 4YKEA 4G9JA 1XM7A 4B2OA 3QG5C 2DFJA 2QJCA 2WDDA 4KBPA 3H60A 1M63A 2BDXA 2YVTA 2KKNA 5JJTA 2DXLA 1II7A 3E7AA 5JPFA 3ZU0A 1S70A 3H69A 3P71C 4O43A 2ZBMA 5DNYA 4UWQA 3K7VC 2Q8UA 4TUIA 1JK7A 3IVDA 5C1VA 1UTEA 3H64A 1QHWA 1G5BA 2XMOA 1S8EA 4LU9A 1HPUA 2Z06A 4WWLA 4O5GA 3LL8A 1WAO1 4I5NC 4LACC 4ORAA 4Q7FA 3DSDA 1V73A 2BQ8X 2R17A 3CK2A 4DSYA 4JA7A 2AHDA 4J6OA 4H2GA 3H68A 4DT2A 3H66A 2YEQA 1OI8A 4MOYA 3KBPA 4OR9A 1UF3A 3JYFA 1T70A 1IT6A 5INBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZVZ A;  4DHL A;  1NNW A;  2CV9 A;  2HY1 A;  2NPP C;  2O8G A;  3K7W C;  3C5W C;  3QFO A;  3THN A;  4MP0 A;  5EQV A;  4H2I A;  1S95 A;  1AUI A;  5J28 A;  3DSC A;  3C9F A;  2WDE A;  2GJU A;  4UT3 A;  3IB7 A;  5GTU A;  4UT2 A;  2O8A A;  4ORC A;  4F0Z A;  2USH A;  2QFR A;  3EGG A;  1S3M A;  5IOH A;  1OID A;  4H2F A;  4UT3 B;  1TCO A;  2WDF A;  4V0V A;  3IB8 A;  2JOG A;  3RL5 A;  1FJM A;  3H62 B;  1USH A;  4FBQ A;  2A22 A;  5F3W A;  2HYO A;  4FBK A;  4ZX2 A;  3AUZ A;  4O24 A;  1SU1 A;  3FGA C;  3QFN A;  4H2B A;  4I5L C;  3H61 A;  4H1S A;  1KBP A;  1QFC A;  4M0V A;  5JPE A;  4TUG A;  2WDC A;  1T71 A;  3RL3 A;  3HVQ A;  3RQZ A;  2NXF A;  2IE4 C;  4HD0 A;  2IE3 C;  4LTY A;  4IL1 A;  1Z2W A;  1WAR A;  1XZW A;  1HO5 A;  3H63 A;  3T1I A;  3N5U A;  3TGH A;  4JA9 A;  4V0X A;  3PSN A;  2P6B A;  2BCD A;  1W24 A;  3E7B A;  4V0W A;  3AV0 A;  2IAE C;  4KKZ A;  1MF8 A;  3DW8 C;  3EGH A;  3RL4 A;  5HPE A;  3ZTV A;  3GVE A;  2QFP A;  4FCX A;  2NYM C;  2HYP A;  3ICF A;  3PSO A;  1HP1 A;  2Z1A A;  4XPN A;  5B8I A;  3QFM A;  1Z2X A;  4IYP C;  3QFK A;  4H1Y P;  4ORB A;  1OIE A;  2NYL C;  1S3L A;  2Z72 A;  4FBW A;  4NZV A;  3IVE A;  3H67 A;  1U32 A;  1S3N A;  4MOV A;  3THO B;  4O4K A;  3V4Y A;  4YKE A;  4G9J A;  1XM7 A;  4B2O A;  3QG5 C;  2DFJ A;  2QJC A;  2WDD A;  4KBP A;  3H60 A;  1M63 A;  2BDX A;  2YVT A;  2KKN A;  5JJT A;  1II7 A;  3E7A A;  5JPF A;  3ZU0 A;  1S70 A;  3H69 A;  3P71 C;  4O43 A;  2ZBM A;  5DNY A;  4UWQ A;  3K7V C;  2Q8U A;  4TUI A;  1JK7 A;  3IVD A;  5C1V A;  1UTE A;  3H64 A;  1QHW A;  1G5B A;  2XMO A;  1S8E A;  4LU9 A;  1HPU A;  2Z06 A;  4WWL A;  4O5G A;  3LL8 A;  1WAO 1;  4I5N C;  4LAC C;  4ORA A;  4Q7F A;  1V73 A;  2R17 A;  2BQ8 X;  3CK2 A;  3DSD A;  4DSY A;  4JA7 A;  2AHD A;  4J6O A;  4H2G A;  3H68 A;  4DT2 A;  3H66 A;  4MOY A;  1OI8 A;  3KBP A;  4OR9 A;  1UF3 A;  3JYF A;  1T70 A;  1IT6 A;  5INB A; 
#chains in the Genus database with same CATH topology
 2HY1 A;  2UU9 E;  5KL7 A;  2LCE A;  4BCA A;  3QFO A;  2E5L E;  4M2Z A;  2LUQ A;  2NAB A;  2EN3 A;  1AUI A;  2EPL X;  2EL4 A;  1HR0 E;  3DSC A;  3H09 A;  3ZOQ B;  5AE3 A;  3C9F A;  2EPU A;  2VRD A;  3E0J A;  5GTU A;  2VF1 A;  3VK6 A;  4WX9 A;  2JPA A;  2LVH A;  4BC9 A;  2EP3 A;  2USH A;  1J5E E;  1O0W A;  4DV0 E;  3EGG A;  1X49 A;  2EE8 A;  3IB8 A;  4F2J C;  3RL5 A;  2WZO A;  4M30 A;  3BF2 A;  1B69 A;  1PKP A;  4RHB B;  1FKA E;  1FJM A;  2EN2 A;  1X6F A;  4FBK A;  4B3T E;  4ZX2 A;  3F6H A;  2EPM X;  5LL6 R;  2WCC 3;  1SU1 A;  3QFN A;  2BBG A;  4DMI A;  3H61 A;  2CT1 A;  1N36 E;  1HNX E;  4DKK A;  5JPE A;  1XNR E;  2B7T A;  4JV5 E;  3LML A;  2HHH E;  4DV3 E;  3HVQ A;  2UUC E;  5A6B A;  3IWC A;  1A1I A;  2EQ3 A;  3BBG A;  3C6K A;  2L2K B;  3UK3 C;  1IMU A;  1WAR A;  4JI6 E;  3T1I A;  2D9H A;  2YTO A;  3N5U A;  2YTG A;  3MHS C;  1MGT A;  2CSH A;  3PSN A;  3VYX A;  3OTO E;  3RL4 A;  1QU6 A;  2EPX A;  4R2Q A;  1IBL E;  3J80 C;  2EMA A;  4RH8 A;  1A1G A;  5B8I A;  3PSO A;  4GZN C;  4JI2 E;  4IYP C;  4H1Y P;  4I8O A;  4ORB A;  2NYL C;  2DB2 A;  5T6J A;  4LF7 E;  2EOH A;  2YT4 A;  4FBW A;  3H67 A;  1U32 A;  2EMH A;  3THO B;  3K6Q A;  2RSI A;  1GQE A;  2ENA A;  4KWY A;  3T1Y E;  2I9I A;  4DR7 E;  1IBM E;  2MDG A;  2VQF E;  2RPC A;  2KKN A;  2UXD E;  1IQS A;  3E7A A;  5JPF A;  4WPY A;  2EOJ A;  2L2N A;  5AC4 A;  4DR3 E;  3ZU0 A;  1S70 A;  5KL5 A;  3HPZ A;  3P71 C;  2R76 A;  2EN4 A;  2ZBM A;  2EL6 A;  3F6G A;  2ENC A;  4TUI A;  3M99 B;  2UUB E;  1YFH A;  4LF5 E;  1UTE A;  1QHW A;  2I13 A;  2J7J A;  4O5G A;  4Q35 B;  2EOQ A;  4I5N C;  2YU8 A;  1V73 A;  2IHR 1;  2FV4 B;  1EKZ A;  2AHD A;  1X5W A;  4H2G A;  3KWR A;  3H66 A;  2EPO A;  1T4N A;  2YEQ A;  1OI8 A;  4MOY A;  4GKJ E;  1EH7 A;  5A6B D;  4N4R B;  5IXM B;  1IT6 A;  4ZVZ A;  4DHL A;  2MC6 A;  1T38 A;  1WJP A;  2WBS A;  5TSE A;  1UIL A;  4X62 E;  3C5W C;  3THN A;  4BHC A;  1KYQ A;  2LMZ A;  1S95 A;  2V85 A;  2YSO A;  2DMY A;  2NA2 A;  4F6N A;  3ADJ A;  4LFC E;  5J28 A;  2JYA A;  5LMN E;  4UT3 A;  1RMD A;  4X64 E;  2EMC A;  4F0Z A;  4DV2 E;  2YRK A;  1S3M A;  5IOH A;  2M7Q A;  4DV6 E;  4F9B B;  4V0V A;  2ZO9 B;  2EOX A;  5IV8 B;  2LT7 A;  2YTI A;  1DGC A;  3LLH A;  5IT9 C;  3H62 B;  4IJD A;  1DI2 A;  4LF8 E;  2A22 A;  2JR1 A;  4JI8 E;  1KJK A;  3RMP A;  2ZOA A;  2B9D A;  1YYO A;  2LJH A;  2EOE A;  4OX9 E;  2VQE E;  2NUE A;  3HTX A;  3AUZ A;  1YYK A;  2E1M A;  2PRT A;  4LF4 E;  2LJU A;  4H1S A;  2LUP B;  5AAS A;  4YHH E;  4K0K E;  4M0V A;  2G7H A;  2ZM6 E;  1T71 A;  3RQZ A;  2EOZ A;  2WBT A;  1HNZ E;  1BBG A;  2DGC A;  4HD0 A;  4IL1 A;  1X6E A;  1Z2W A;  4JYA E;  1ZR9 A;  1HO5 A;  1XZW A;  2YRM A;  4ZYE A;  2M4I A;  2V83 A;  4JA9 A;  2M1S A;  3TGH A;  2P6B A;  1W24 A;  5BR8 E;  4NHR A;  2EM8 A;  4KKZ A;  3DW8 C;  3HPS A;  1A1K A;  3J81 C;  2L2M A;  2YTP A;  3DJW A;  4IS1 C;  3EQ1 A;  4KZS A;  2EMK A;  1AAY A;  2DSY A;  3D03 A;  4BHB A;  3GVE A;  2V89 A;  4FCX A;  3ICF A;  4XPN A;  2Z1A A;  1MEY C;  3MSW A;  4X65 E;  5LMU E;  3QFM A;  2EPZ A;  4DV1 E;  3QFK A;  2HC5 A;  1RQ0 A;  1OIE A;  2Z72 A;  1RC7 A;  1NEI A;  2YWQ A;  2RSM A;  2JOB A;  2B7V A;  4ZYD A;  4BS9 A;  1WRJ A;  2EM6 A;  2V87 A;  2B3T B;  4R2P A;  2EM4 A;  1F2I G;  1A1F A;  4YKE A;  2EMX A;  2EM7 A;  1G2D C;  4B2O A;  3QG5 C;  2DFJ A;  2ELZ A;  2LO3 A;  1YUI A;  2EMW A;  2EN6 A;  2UXB E;  5IWA E;  3EPL A;  2BDX A;  2YVT A;  4R03 A;  2L3C A;  4OOG C;  2WBU A;  1II7 A;  4DUZ E;  3EPJ A;  4AQY E;  2FGG A;  2M9A A;  2YTD A;  4ZYH A;  1P47 A;  1J26 A;  1TF6 A;  2L33 A;  1XMQ E;  1FJG E;  3K7V C;  1ZU1 A;  2L92 A;  2L6M A;  2K4V A;  4WFT A;  2XMO A;  5AC5 A;  2UUA E;  1HPU A;  4LAC C;  3LL8 A;  4ORA A;  2YSP A;  1T4O A;  3C4B A;  2A25 A;  4DSY A;  5AE1 A;  3HQ1 A;  1BBO A;  2V88 A;  4JI4 E;  2EM3 A;  4MP0 A;  5INB A;  4DR5 E;  1PDA A;  3EPK A;  1NNW A;  2NPP C;  4R2S A;  4R2A A;  2O8G A;  5A6A A;  3K7W C;  1UHZ A;  4H2I A;  2EOS A;  2YTE A;  1YZ9 A;  4FK5 C;  4M9V C;  1QNT A;  3ECR A;  2EQ1 A;  1IBK E;  4X8W A;  3MHH C;  4LFB E;  2GJU A;  2WDE A;  1ZBT A;  3IB7 A;  4R8O A;  4UT2 A;  2EPA A;  2O8A A;  1N32 E;  2CPN A;  4BMJ A;  3OML A;  1GTK A;  2KOU A;  1A1J A;  2CTD A;  1EH6 A;  1OID A;  4F6M A;  1YUJ A;  2ELY A;  2LV2 A;  4H2F A;  4LF6 E;  2ODR C;  2WDF A;  2EMI A;  1IQO A;  1GZ6 A;  2EM2 A;  1G2F C;  4NXM E;  2EML A;  4DV5 E;  4FBQ A;  3P1X A;  2EQ0 A;  2DXN A;  3EPH A;  2HYO A;  2LE2 A;  2UXC E;  2EPC A;  4O24 A;  4I5L C;  2EMZ A;  1KBP A;  2ADR A;  4X9J A;  2KHX A;  2L3J A;  3VYY A;  2EMG A;  3RL3 A;  2JWO A;  2ODR D;  4DUY E;  2NXF A;  2IE4 C;  2IE3 C;  2YRH A;  3BID A;  4JI5 E;  3H63 A;  1XNQ E;  4ZYG A;  3T1H E;  2GLI A;  4V0X A;  2K7I A;  2IAE C;  2BB8 A;  3J7A G;  3IWB A;  3EGH A;  2E72 A;  2YTQ A;  4MLV A;  5HPE A;  1WXR A;  3ZTV A;  1X48 A;  2YZT A;  4WSP A;  4BC7 A;  1N33 E;  2LRS A;  4Q28 A;  2R1F A;  1T4L B;  1NCS A;  2DRP A;  1SR9 A;  4J8Z A;  2N3G A;  1UBD C;  3J7Y p;  1S3L A;  3IVE A;  1TF3 A;  1L4S A;  1S3N A;  4WXC A;  2EPR A;  2EMY A;  4O4K A;  5KL3 A;  2JVA A;  2DIX A;  4MLQ A;  2YPN A;  1XM7 A;  5CFF E;  2QJC A;  2WDD A;  4LF9 E;  2EOO A;  1WHN A;  4KBP A;  5A69 A;  2V86 A;  5JJT A;  1XMO E;  2EZ6 A;  3BGH A;  2DXL A;  1STU A;  5A6K A;  4JI3 E;  4O43 A;  2F8B A;  2EOF A;  2Q8U A;  1JK7 A;  3IVD A;  5C1V A;  1N34 E;  2MC5 A;  2RTX A;  2EN7 A;  1G5B A;  3TQM A;  2MDR A;  4JI1 E;  3DF6 A;  4KHP E;  4WWL A;  1WAO 1;  4Q7F A;  4X66 E;  3CK2 A;  4DR1 E;  2BQ8 X;  3C6M A;  2VE7 C;  4JA7 A;  2HJJ A;  3ADG A;  4J6O A;  3ADL A;  4B3M E;  3H68 A;  1ZBQ A;  3KBP A;  2LTS A;  1T39 A;  1UF3 A;  3JYF A;  2EWL A;  2KON A;  1T70 A;  1A1L A;  2CV9 A;  3FLO A;  4B3R E;  2EM5 A;  5EQV A;  2JP9 A;  2EN1 A;  2EMF A;  2JXP A;  3JU0 A;  1ZAA C;  4R2D A;  2DLK A;  1X6H A;  5KL4 A;  4JI0 E;  4WYQ B;  4YY3 E;  2V8Q B;  4ORC A;  4JI7 E;  3JAM C;  1YPN A;  2QFR A;  2NUG A;  4L5N C;  2GPI A;  4UT3 B;  1PJS A;  1TCO A;  2DLQ A;  4DV4 E;  4HEI A;  3ADI A;  3KZY A;  2JOG A;  2EJ4 A;  2N3H A;  3JTZ A;  5AE2 A;  1USH A;  1PJT A;  4R2E A;  4GKK E;  1YYW A;  2RS6 A;  2ENH A;  1Z1B A;  2EPN A;  3FGA C;  4LFA E;  4H2B A;  2YTN A;  1JK2 A;  5A2Q C;  5A6J A;  4B3S E;  1QFC A;  1WHQ A;  5ADZ A;  1DQ3 A;  2WDC A;  5KL6 A;  4BBY A;  2YTF A;  4LTY A;  4R2C A;  1BB8 A;  2EPP A;  1LLM C;  3FIG A;  2BCD A;  4V0W A;  3E7B A;  3AV0 A;  1MF8 A;  5FLX C;  4R2R A;  3C4T A;  4NXN E;  4F54 A;  1X47 A;  2QFP A;  4P78 A;  4DR6 E;  2HYP A;  2NYM C;  1HP1 A;  1X3C A;  4GEQ B;  1A1H A;  2JY9 A;  1Z2X A;  1AH5 A;  1N3G A;  2EOM A;  4NZV A;  4DR4 E;  2L8T A;  3L00 A;  4HTG A;  4MOV A;  3V4Y A;  2MKN A;  2N8X A;  3HXL A;  2JOX A;  2MKD A;  4G9J A;  2H36 X;  2RS7 A;  2EM0 A;  3KZZ A;  3H60 A;  1M63 A;  4F9C B;  1YSA C;  2EM9 A;  2YTJ A;  4DR2 E;  2GHF A;  4DV7 E;  4WSG A;  1I94 E;  2F4V E;  2HGH A;  2RQL A;  3H69 A;  2NUF A;  2LTR A;  2EOI A;  4F9A B;  5KL2 A;  5DNY A;  2EMB A;  4UWQ A;  2DMI A;  1EH8 A;  2EN8 A;  3H64 A;  1S8E A;  4LU9 A;  4TUG A;  2Z06 A;  1HNW E;  2LBS B;  4L8N A;  2FTX B;  2EL5 A;  1TN9 A;  2R17 A;  3DSD A;  1SFE A;  5LLQ A;  2YU5 A;  4DT2 A;  3VHT B;  1UN6 B;  1PJQ A;  4WXD A;  3IWD A;  2EPK X;  4OR9 A;  2EOR A;  2EOY A;  4P7D A;  1JK1 A;  5F3W A; 
#chains in the Genus database with same CATH homology
 4ZVZ A;  4DHL A;  1NNW A;  2CV9 A;  2HY1 A;  2NPP C;  3FLO A;  2O8G A;  3K7W C;  3C5W C;  3QFO A;  3THN A;  4MP0 A;  5EQV A;  4H2I A;  1S95 A;  1AUI A;  3DSC A;  5J28 A;  3C9F A;  2WDE A;  2GJU A;  3E0J A;  3IB7 A;  4UT3 A;  5GTU A;  4UT2 A;  2O8A A;  4ORC A;  4F0Z A;  2USH A;  2QFR A;  3EGG A;  1S3M A;  5IOH A;  1OID A;  4H2F A;  4UT3 B;  1TCO A;  2WDF A;  4V0V A;  3IB8 A;  2ZO9 B;  2JOG A;  3RL5 A;  1FJM A;  3H62 B;  1USH A;  4FBQ A;  2A22 A;  5F3W A;  2DXN A;  2HYO A;  4FBK A;  2ZOA A;  4ZX2 A;  3AUZ A;  4O24 A;  1SU1 A;  3FGA C;  3QFN A;  4H2B A;  4I5L C;  3H61 A;  4H1S A;  1KBP A;  1QFC A;  4M0V A;  5JPE A;  4TUG A;  2WDC A;  1T71 A;  3RL3 A;  3HVQ A;  3RQZ A;  2NXF A;  2IE4 C;  4HD0 A;  2IE3 C;  4LTY A;  4IL1 A;  1Z2W A;  1WAR A;  1XZW A;  1HO5 A;  3H63 A;  3T1I A;  3N5U A;  3TGH A;  4JA9 A;  4V0X A;  3PSN A;  2P6B A;  2BCD A;  1W24 A;  3E7B A;  4V0W A;  3AV0 A;  2IAE C;  4KKZ A;  1MF8 A;  3DW8 C;  3EGH A;  3RL4 A;  5HPE A;  3ZTV A;  3D03 A;  3GVE A;  2QFP A;  4FCX A;  2NYM C;  2HYP A;  3ICF A;  3PSO A;  1HP1 A;  2Z1A A;  4XPN A;  5B8I A;  3QFM A;  1Z2X A;  4IYP C;  3QFK A;  4H1Y P;  4ORB A;  1OIE A;  2NYL C;  1S3L A;  2Z72 A;  4FBW A;  4NZV A;  3IVE A;  3H67 A;  1U32 A;  1S3N A;  4MOV A;  3THO B;  4O4K A;  3V4Y A;  4YKE A;  4G9J A;  1XM7 A;  4B2O A;  3QG5 C;  2DFJ A;  2QJC A;  2WDD A;  4KBP A;  3H60 A;  1M63 A;  2BDX A;  2YVT A;  2KKN A;  5JJT A;  2DXL A;  1II7 A;  3E7A A;  5JPF A;  3ZU0 A;  1S70 A;  3H69 A;  3P71 C;  4O43 A;  2ZBM A;  5DNY A;  4UWQ A;  3K7V C;  2Q8U A;  4TUI A;  1JK7 A;  3IVD A;  5C1V A;  1UTE A;  3H64 A;  1QHW A;  1G5B A;  2XMO A;  1S8E A;  4LU9 A;  1HPU A;  2Z06 A;  4WWL A;  4O5G A;  3LL8 A;  1WAO 1;  4I5N C;  4LAC C;  4ORA A;  4Q7F A;  3DSD A;  1V73 A;  2BQ8 X;  2R17 A;  3CK2 A;  4DSY A;  4JA7 A;  2AHD A;  4J6O A;  4H2G A;  3H68 A;  4DT2 A;  3H66 A;  2YEQ A;  1OI8 A;  4MOY A;  3KBP A;  4OR9 A;  1UF3 A;  3JYF A;  1T70 A;  1IT6 A;  5INB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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