4O24A

Dna double-strand break repair pathway choice is directed by distinct mre11 nuclease activities
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
331
structure length
331
Chain Sequence
IHHHHHHVINLKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGNHDWKGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPDESEALRKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAGYAGIEQGREIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNFPGYVRVVYEEDSGILPDLMGEIDNLVKIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities.
pubmed doi rcsb
molecule tags Dna binding protein/inhibitor
source organism Thermotoga maritima
molecule keywords Exonuclease, putative
total genus 101
structure length 331
sequence length 331
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.160.210 Alpha Beta 2-Layer Sandwich Double Stranded RNA Binding Domain DNA double-strand break repair nuclease 4o24A02
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 4o24A01
3ZTVA 3DSCA 1MF8A 2GJUA 1KBPA 4JA7A 3P71C 3LL8A 2USHA 1SU1A 3H63A 4I5LC 2NYLC 4FBWA 4H2IA 2NXFA 2O8AA 2QFPA 4UWQA 4TUGA 2P6BA 4ZVZA 2Z1AA 4O4KA 2WDFA 3QFKA 3C5WC 2Z06A 1QFCA 4HD0A 3THNA 1IT6A 1T70A 4DSYA 3N5UA 3RQZA 1S3NA 1HP1A 1Z2XA 2HY1A 4O5GA 2BCDA 1W24A 4LTYA 1Z2WA 3PSNA 2NYMC 1V73A 2DFJA 2YVTA 4LU9A 4Q7FA 1XM7A 4UT3A 3H62B 3IVDA 3H61A 4DT2A 5IOHA 1QHWA 2QJCA 2JOGA 3QFNA 1S3MA 3V4YA 2WDDA 2HYOA 1S95A 3PSOA 1OIEA 1UTEA 3RL5A 4MP0A 1XZWA 4KKZA 2Q8UA 2XMOA 4H2BA 5GTUA 4M0VA 4OR9A 1JK7A 1HO5A 4FCXA 3EGGA 1HPUA 2R17A 2CV9A 1AUIA 3HVQA 4H1YP 4H1SA 1TCOA 2IE3C 3C9FA 3RL4A 3GVEA 3T1IA 5F3WA 4J6OA 5JPFA 1U32A 1UF3A 3E7BA 5INBA 5JJTA 3AV0A 4H2GA 4H2FA 4ORBA 3ZU0A 3QFOA 3JYFA 5HPEA 3K7WC 4TUIA 3DSDA 4KBPA 4LACC 3H64A 3H68A 5J28A 4F0ZA 2Z72A 3K7VC 2A22A 4O43A 1II7A 4UT3B 4ORCA 4ZX2A 3E7AA 1NNWA 3H66A 1USHA 2AHDA 1T71A 1S70A 1WARA 3H69A 1WAO1 1G5BA 3FGAC 2NPPC 3IB7A 4O24A 4MOYA 4V0XA 4WWLA 2BDXA 4IL1A 1S8EA 4FBQA 2WDEA 3ICFA 3IVEA 4XPNA 3RL3A 5B8IA 2O8GA 2KKNA 4NZVA 4JA9A 5DNYA 2QFRA 4IYPC 2HYPA 4V0WA 1S3LA 1OIDA 3DW8C 4B2OA 3H67A 4G9JA 2BQ8X 4YKEA 3IB8A 4MOVA 3AUZA 5EQVA 3H60A 2ZBMA 1FJMA 1M63A 5JPEA 4ORAA 4UT2A 4I5NC 2WDCA 3THOB 2IE4C 3CK2A 3TGHA 3KBPA 5C1VA 2IAEC 3EGHA 4DHLA 3QG5C 3QFMA 4V0VA 4FBKA 1OI8A
chains in the Genus database with same CATH superfamily
2EM2A 2EN7A 2YTIA 3JTZA 2EOXA 1ZBQA 1MGTA 3P71C 3LMLA 2I9IA 2LMZA 4NXME 3EPJA 4I5LC 2NABA 2NXFA 4H2IA 4WX9A 1PDAA 4UWQA 3UK3C 1X47A 2LO3A 4DR6E 2JYAA 2EMBA 2V83A 4BCAA 2WDFA 1TF6A 2JR1A 2LRSA 3T1YE 2NUEA 1A1KA 1T70A 2LCEA 3VYYA 1T4OA 3N5UA 2EOMA 4WXCA 2J7JA 4O5GA 2EMFA 3RMPA 4JYAE 3EPKA 2EMLA 2GPIA 2VQFE 4DV3E 2NYMC 4LU9A 4ZYDA 2RSMA 2EN2A 3H62B 3IVDA 4WSPA 4LFAE 3H61A 3TQMA 1GZ6A 2QJCA 1HR0E 1S3MA 3V4YA 2EPKX 1ZAAC 2EM9A 2EPAA 1HNZE 1S95A 1OIEA 3RL5A 2FTXB 1XZWA 3ADGA 4P78A 2XMOA 4DKKA 5GTUA 4BC9A 2ODRD 1HO5A 2LJHA 5AE2A 2UUAE 3VK6A 1AUIA 5AC5A 2MKDA 5FLXC 4H1SA 2YTJA 3C9FA 1X6HA 2UUBE 2L3JA 1T4NA 4F6NA 2EPRA 5LMUE 3D03A 3E7BA 1N3GA 5LLQA 2MKNA 5JJTA 1WRJA 4X65E 3M99B 3C6MA 1PJQA 3H09A 2YTFA 2LVHA 1UBDC 2JOBA 3K7WC 4KBPA 4LACC 2BBGA 2B3TB 2L33A 4KHPE 3K7VC 5AE1A 1T38A 4IS1C 2YWQA 3MHSC 2E5LE 2YRMA 3EPHA 1USHA 2AHDA 3H69A 2EL4A 1G5BA 1HNXE 2NPPC 3BIDA 4J8ZA 1JK1A 4WWLA 5AE3A 2EM7A 1QNTA 2EM4A 3ICFA 2DXNA 4R03A 2L2KB 1L4SA 2HGHA 3C4TA 2UUCE 4IYPC 4B2OA 2EM8A 4JI2E 5EQVA 2LE2A 2EE8A 4GZNC 4DV0E 1QU6A 4BS9A 3F6HA 3THOB 2IE4C 3CK2A 4GKJE 3TGHA 2RPCA 1EKZA 3QG5C 3FLOA 5IWAE 2EMKA 3DSCA 2EMIA 5LL6R 1MF8A 4KZSA 2EOSA 4BHBA 3JAMC 4B3TE 2ENAA 2MC6A 3LL8A 2N3GA 2B9DA 3H63A 2M1SA 2HJJA 2MDGA 4TUGA 4I8OA 4WYQB 1DQ3A 4ZVZA 4YY3E 2YRHA 2YSOA 3L00A 4P7DA 4O4KA 1EH8A 4WSGA 3OMLA 4DMIA 5BR8E 3C5WC 3THNA 5IXMB 4X64E 5KL4A 1IBKE 1WXRA 1UILA 5A6AA 1P47A 2LTSA 2G7HA 1Z2XA 2EQ1A 2UXCE 1IBLE 1YZ9A 2RS7A 2UXDE 1W24A 4JI4E 2RQLA 2DRPA 4LF8E 2EQ3A 4R8OA 1IMUA 2JOXA 4RHBB 1XM7A 4B3ME 4LF6E 2NA2A 2ELZA 1QHWA 2JOGA 3QFNA 2E1MA 2HYOA 5IT9C 1T39A 2DMIA 2V85A 2DXLA 2ENHA 2WZOA 4M0VA 1BBGA 2CPNA 2EOYA 5ADZA 2M9AA 4JI6E 2CV9A 4JI1E 2F4VE 2LBSB 2EN4A 5A6BA 1TCOA 3J81C 2WBSA 3JU0A 2H36X 4MLQA 4Q28A 5TSEA 1DI2A 2V87A 3J7AG 1BB8A 1TN9A 1RQ0A 4F6MA 4R2SA 3AV0A 2CSHA 3ZU0A 5HPEA 2NUFA 3QFOA 1AH5A 4HEIA 4TUIA 2FGGA 3H68A 4B3SE 2EN8A 2L6MA 1A1FA 1YUIA 2Z72A 1PKPA 2A22A 1IBME 2EPLX 1PJTA 2UU9E 2K7IA 3DJWA 4LFBE 4LF4E 4ORCA 1WHQA 4BBYA 3LLHA 5A6BD 3EQ1A 2UXBE 5AASA 2EMXA 1WHNA 2RTXA 2WCC3 1S70A 1WARA 3J80C 2YPNA 1EH7A 4RH8A 1TF3A 2EMCA 4NHRA 4FBQA 2WDEA 4XPNA 3VHTB 1X49A 5B8IA 3HXLA 5KL3A 1YFHA 2EQ0A 4NZVA 2ZO9B 1XNQE 1S3LA 2JXPA 1OIDA 3DW8C 2L8TA 3H67A 4G9JA 3IB8A 3AUZA 3H60A 3DF6A 5JPEA 2KONA 4KWYA 1F2IG 2LTRA 2NUGA 3KBPA 4DV7E 3EGHA 4JI0E 4X62E 4LF5E 4ZYGA 1X48A 4NXNE 3ZTVA 5IV8B 2GJUA 5LMNE 1LLMC 1SU1A 2LJUA 4FBWA 2O8AA 4X8WA 2L92A 1ZR9A 2P6BA 2Z1AA 2EP3A 3KZYA 4AQYE 3QFKA 2EPXA 4BHCA 2Z06A 4HD0A 4GEQB 1IT6A 4ZYEA 3RQZA 4IJDA 3F6GA 4M30A 2PRTA 4Q35B 4JV5E 2BCDA 2HY1A 2YTDA 3EPLA 4WPYA 2EPCA 3T1HE 1J26A 2KOUA 4LTYA 4DV4E 1Z2WA 3HQ1A 1XMOE 1B69A 2N8XA 1XNRE 3PSNA 1V73A 2D9HA 1G2DC 2I13A 2YVTA 2L2MA 4Q7FA 2MC5A 4UT3A 1PJSA 2EN6A 4F9AB 5A69A 4DT2A 2E72A 2HHHE 2DSYA 1SFEA 2WDDA 3ADJA 4F54A 2EORA 1UTEA 1J5EE 2JVAA 4MP0A 2WBUA 4H2BA 4OR9A 1STUA 3FIGA 1SR9A 4BMJA 3HVQA 1JK2A 2ADRA 4HTGA 4R2CA 2IE3C 2JP9A 4DV6E 3RL4A 2V88A 3GVEA 3T1IA 4WFTA 1ZBTA 2EOFA 2FV4B 2V86A 5T6JA 5KL7A 3KZZA 1UF3A 3C6KA 1XMQE 4DR7E 4H2GA 2EZ6A 1A1GA 3DSDA 1YUJA 1YPNA 3H64A 5J28A 3OTOE 4F0ZA 1O0WA 1YYOA 3MSWA 3MHHC 4OOGC 4O43A 5KL6A 4DR1E 4DV2E 1FKAE 2EOJA 3BBGA 4UT3B 2LUPB 2YTNA 1YSAC 4L5NC 2GHFA 2VQEE 1N32E 2DLQA 3E7AA 2BB8A 1NNWA 3H66A 1ZU1A 1Z1BA 1T71A 1IQSA 1WAO1 1AAYA 3J7Yp 5KL2A 3FGAC 4MOYA 3IB7A 4O24A 2A25A 1T4LB 2EMGA 2EPMX 1X3CA 4DV5E 3IVEA 2R76A 3RL3A 2O8GA 1GTKA 4K0KE 2KKNA 5A6JA 4DR3E 2F8BA 2N3HA 2EOZA 2EMHA 2EOOA 4MOVA 3BGHA 2GLIA 2EL5A 1FJMA 1M63A 4JI3E 4UT2A 2DIXA 2DLKA 2EMYA 2V8QB 2WDCA 3IWDA 1A1HA 2DGCA 4BC7A 5C1VA 3HPSA 3IWCA 4B3RE 3QFMA 2EPOA 2B7TA 2ODRC 4FBKA 2EPUA 4V0VA 1RMDA 4FK5C 4YHHE 1NCSA 2LV2A 2EM0A 1KBPA 4JA7A 2ELYA 2MDRA 2USHA 4LFCE 2EJ4A 5A6KA 5CFFE 3VYXA 2NYLC 2M4IA 2QFPA 2V89A 4DR5E 1KJKA 2EN3A 3HTXA 1YYKA 4JI8E 2EOEA 1QFCA 3ADIA 2EMZA 2YTGA 2YZTA 4R2PA 4DSYA 1IQOA 4F2JC 1S3NA 1HP1A 1G2FC 4N4RB 1WJPA 1UHZA 4L8NA 2YTOA 4F9CB 2K4VA 2EN1A 4F9BB 2YTPA 2DFJA 2EM5A 1RC7A 4R2DA 2EMAA 1BBOA 1NEIA 4R2RA 2YT4A 2YSPA 5IOHA 2VF1A 2R1FA 1X5WA 2LT7A 3PSOA 2B7VA 1I94E 2JPAA 4KKZA 2CT1A 2Q8UA 3HPZA 2WBTA 1JK7A 2EWLA 2YRKA 4FCXA 1KYQA 2DB2A 1EH6A 3EGGA 1HPUA 3ADLA 2IHR1 2R17A 2RS6A 4H1YP 3K6QA 2ZOAA 2L3CA 1GQEA 1A1LA 2EOQA 4OX9E 2EM6A 5F3WA 4R2AA 4J6OA 4X66E 5JPFA 1HNWE 1U32A 4LF9E 5INBA 4R2EA 4DR4E 2VRDA 4H2FA 4WXDA 3JYFA 4MLVA 2EOIA 2KHXA 4ORBA 2DMYA 2YU8A 4DUZE 2ZM6E 1MEYC 2HC5A 2M7QA 3P1XA 1X6EA 1N36E 4LF7E 1N33E 1II7A 2EPPA 2EPNA 3C4BA 2CTDA 2JY9A 4ZX2A 5KL5A 2EL6A 2EOHA 2YTQA 3KWRA 3ZOQB 2RSIA 4V0XA 2VE7C 1A1JA 2YU5A 1UN6B 2BDXA 1DGCA 4DUYE 4IL1A 4M9VC 1S8EA 1FJGE 4R2QA 2YTEA 2YEQA 5AC4A 4JI7E 5DNYA 4JA9A 2QFRA 2HYPA 4V0WA 1YYWA 3IWBA 4ZYHA 4YKEA 2BQ8X 2JWOA 2EMWA 1A1IA 2ZBMA 1X6FA 3BF2A 2LUQA 4ORAA 2EPZA 4X9JA 5A2QC 4I5NC 1N34E 4JI5E 4GKKE 2EM3A 3E0JA 2L2NA 2IAEC 4DHLA 4DR2E 2ENCA 1OI8A 4M2ZA 3ECRA 4DV1E
chains in the Genus database with same CATH topology
3ZTVA 3DSCA 1MF8A 2GJUA 1KBPA 4JA7A 3P71C 3LL8A 2USHA 1SU1A 3H63A 4I5LC 2NYLC 4FBWA 4H2IA 2NXFA 2O8AA 2QFPA 4UWQA 4TUGA 2P6BA 4ZVZA 2Z1AA 4O4KA 2WDFA 3QFKA 3C5WC 2Z06A 1QFCA 4HD0A 3THNA 1IT6A 1T70A 4DSYA 3N5UA 3RQZA 1S3NA 1HP1A 1Z2XA 2HY1A 4O5GA 2BCDA 1W24A 4LTYA 1Z2WA 3PSNA 2NYMC 1V73A 2DFJA 2YVTA 4LU9A 4Q7FA 1XM7A 4UT3A 3H62B 3IVDA 3H61A 4DT2A 5IOHA 1QHWA 2QJCA 2JOGA 3QFNA 1S3MA 3V4YA 2WDDA 2HYOA 1S95A 3PSOA 1OIEA 1UTEA 3RL5A 4MP0A 1XZWA 4KKZA 2Q8UA 2DXLA 2XMOA 4H2BA 5GTUA 4M0VA 4OR9A 1JK7A 1HO5A 4FCXA 3EGGA 1HPUA 2CV9A 2R17A 1AUIA 3HVQA 4H1YP 4H1SA 1TCOA 2IE3C 3C9FA 3RL4A 3GVEA 3T1IA 5F3WA 3D03A 4J6OA 5JPFA 1U32A 1UF3A 3E7BA 5INBA 5JJTA 3AV0A 4H2GA 4H2FA 4ORBA 3ZU0A 3QFOA 3JYFA 5HPEA 3K7WC 3DSDA 4TUIA 4KBPA 4LACC 3H64A 3H68A 5J28A 4F0ZA 2Z72A 3K7VC 2A22A 4O43A 1II7A 4UT3B 4ORCA 4ZX2A 3E7AA 1NNWA 3H66A 1USHA 2AHDA 1T71A 1S70A 1WARA 3H69A 1WAO1 1G5BA 3FGAC 2NPPC 3IB7A 4O24A 4MOYA 4V0XA 4WWLA 2BDXA 4IL1A 1S8EA 4FBQA 2WDEA 3ICFA 2DXNA 3IVEA 4XPNA 3RL3A 5B8IA 2YEQA 2O8GA 2KKNA 4NZVA 4JA9A 5DNYA 2QFRA 2ZO9B 4IYPC 2HYPA 4V0WA 1S3LA 1OIDA 3DW8C 4B2OA 3H67A 4G9JA 2BQ8X 4YKEA 3IB8A 4MOVA 3AUZA 5EQVA 3H60A 2ZBMA 1FJMA 1M63A 5JPEA 4ORAA 4UT2A 4I5NC 2WDCA 3THOB 2IE4C 3CK2A 3E0JA 3TGHA 3KBPA 5C1VA 2IAEC 3EGHA 4DHLA 3QG5C 3FLOA 3QFMA 4FBKA 1OI8A 4V0VA 2ZOAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZTV A;  3DSC A;  1MF8 A;  2GJU A;  1KBP A;  4JA7 A;  3P71 C;  3LL8 A;  2USH A;  1SU1 A;  3H63 A;  4I5L C;  2NYL C;  4FBW A;  4H2I A;  2NXF A;  2O8A A;  2QFP A;  4UWQ A;  4TUG A;  2P6B A;  4ZVZ A;  2Z1A A;  4O4K A;  2WDF A;  3QFK A;  3C5W C;  2Z06 A;  1QFC A;  4HD0 A;  3THN A;  1IT6 A;  1T70 A;  4DSY A;  3N5U A;  3RQZ A;  1S3N A;  1HP1 A;  1Z2X A;  2HY1 A;  4O5G A;  2BCD A;  1W24 A;  4LTY A;  1Z2W A;  3PSN A;  2NYM C;  1V73 A;  2DFJ A;  2YVT A;  4LU9 A;  4Q7F A;  1XM7 A;  4UT3 A;  3H62 B;  3IVD A;  3H61 A;  4DT2 A;  5IOH A;  1QHW A;  2QJC A;  2JOG A;  3QFN A;  1S3M A;  3V4Y A;  2WDD A;  2HYO A;  1S95 A;  3PSO A;  1OIE A;  1UTE A;  3RL5 A;  4MP0 A;  1XZW A;  4KKZ A;  2Q8U A;  2XMO A;  4H2B A;  5GTU A;  4M0V A;  4OR9 A;  1JK7 A;  1HO5 A;  4FCX A;  3EGG A;  1HPU A;  2R17 A;  2CV9 A;  1AUI A;  3HVQ A;  4H1Y P;  4H1S A;  1TCO A;  2IE3 C;  3C9F A;  3RL4 A;  3GVE A;  3T1I A;  5F3W A;  4J6O A;  5JPF A;  1U32 A;  1UF3 A;  3E7B A;  5INB A;  5JJT A;  3AV0 A;  4H2G A;  4H2F A;  4ORB A;  3ZU0 A;  3QFO A;  3JYF A;  5HPE A;  3K7W C;  4TUI A;  3DSD A;  4KBP A;  4LAC C;  3H64 A;  3H68 A;  5J28 A;  4F0Z A;  2Z72 A;  3K7V C;  2A22 A;  4O43 A;  1II7 A;  4UT3 B;  4ORC A;  4ZX2 A;  3E7A A;  1NNW A;  3H66 A;  1USH A;  2AHD A;  1T71 A;  1S70 A;  1WAR A;  3H69 A;  1WAO 1;  1G5B A;  3FGA C;  2NPP C;  3IB7 A;  4O24 A;  4MOY A;  4V0X A;  4WWL A;  2BDX A;  4IL1 A;  1S8E A;  4FBQ A;  2WDE A;  3ICF A;  3IVE A;  4XPN A;  3RL3 A;  5B8I A;  2O8G A;  2KKN A;  4NZV A;  4JA9 A;  5DNY A;  2QFR A;  4IYP C;  2HYP A;  4V0W A;  1S3L A;  1OID A;  3DW8 C;  4B2O A;  3H67 A;  4G9J A;  2BQ8 X;  4YKE A;  3IB8 A;  4MOV A;  3AUZ A;  5EQV A;  3H60 A;  2ZBM A;  1FJM A;  1M63 A;  5JPE A;  4ORA A;  4UT2 A;  4I5N C;  2WDC A;  3THO B;  2IE4 C;  3CK2 A;  3TGH A;  3KBP A;  5C1V A;  2IAE C;  3EGH A;  4DHL A;  3QG5 C;  3QFM A;  4V0V A;  4FBK A;  1OI8 A; 
#chains in the Genus database with same CATH topology
 2EM2 A;  2EN7 A;  2YTI A;  3JTZ A;  2EOX A;  1ZBQ A;  1MGT A;  3P71 C;  3LML A;  2I9I A;  2LMZ A;  4NXM E;  3EPJ A;  4I5L C;  2NAB A;  2NXF A;  4H2I A;  4WX9 A;  1PDA A;  4UWQ A;  3UK3 C;  1X47 A;  2LO3 A;  4DR6 E;  2JYA A;  2EMB A;  2V83 A;  4BCA A;  2WDF A;  1TF6 A;  2JR1 A;  2LRS A;  3T1Y E;  2NUE A;  1A1K A;  1T70 A;  2LCE A;  3VYY A;  1T4O A;  3N5U A;  2EOM A;  4WXC A;  2J7J A;  4O5G A;  2EMF A;  3RMP A;  4JYA E;  3EPK A;  2EML A;  2GPI A;  2VQF E;  4DV3 E;  2NYM C;  4LU9 A;  4ZYD A;  2RSM A;  2EN2 A;  3H62 B;  3IVD A;  4WSP A;  4LFA E;  3H61 A;  3TQM A;  1GZ6 A;  2QJC A;  1HR0 E;  1S3M A;  3V4Y A;  2EPK X;  1ZAA C;  2EM9 A;  2EPA A;  1HNZ E;  1S95 A;  1OIE A;  3RL5 A;  2FTX B;  1XZW A;  3ADG A;  4P78 A;  2XMO A;  4DKK A;  5GTU A;  4BC9 A;  2ODR D;  1HO5 A;  2LJH A;  5AE2 A;  2UUA E;  3VK6 A;  1AUI A;  5AC5 A;  2MKD A;  5FLX C;  4H1S A;  2YTJ A;  3C9F A;  1X6H A;  2UUB E;  2L3J A;  1T4N A;  4F6N A;  2EPR A;  5LMU E;  3D03 A;  3E7B A;  1N3G A;  5LLQ A;  2MKN A;  5JJT A;  1WRJ A;  4X65 E;  3M99 B;  3C6M A;  1PJQ A;  3H09 A;  2YTF A;  2LVH A;  1UBD C;  2JOB A;  3K7W C;  4KBP A;  4LAC C;  2BBG A;  2B3T B;  2L33 A;  4KHP E;  3K7V C;  5AE1 A;  1T38 A;  4IS1 C;  2YWQ A;  3MHS C;  2E5L E;  2YRM A;  3EPH A;  1USH A;  2AHD A;  3H69 A;  2EL4 A;  1G5B A;  1HNX E;  2NPP C;  3BID A;  4J8Z A;  1JK1 A;  4WWL A;  5AE3 A;  2EM7 A;  1QNT A;  2EM4 A;  3ICF A;  2DXN A;  4R03 A;  2L2K B;  1L4S A;  2HGH A;  3C4T A;  2UUC E;  4IYP C;  4B2O A;  2EM8 A;  4JI2 E;  5EQV A;  2LE2 A;  2EE8 A;  4GZN C;  4DV0 E;  1QU6 A;  4BS9 A;  3F6H A;  3THO B;  2IE4 C;  3CK2 A;  4GKJ E;  3TGH A;  2RPC A;  1EKZ A;  3QG5 C;  3FLO A;  5IWA E;  2EMK A;  3DSC A;  2EMI A;  5LL6 R;  1MF8 A;  4KZS A;  2EOS A;  4BHB A;  3JAM C;  4B3T E;  2ENA A;  2MC6 A;  3LL8 A;  2N3G A;  2B9D A;  3H63 A;  2M1S A;  2HJJ A;  2MDG A;  4TUG A;  4I8O A;  4WYQ B;  1DQ3 A;  4ZVZ A;  4YY3 E;  2YRH A;  2YSO A;  3L00 A;  4P7D A;  4O4K A;  1EH8 A;  4WSG A;  3OML A;  4DMI A;  5BR8 E;  3C5W C;  3THN A;  5IXM B;  4X64 E;  5KL4 A;  1IBK E;  1WXR A;  1UIL A;  5A6A A;  1P47 A;  2LTS A;  2G7H A;  1Z2X A;  2EQ1 A;  2UXC E;  1IBL E;  1YZ9 A;  2RS7 A;  2UXD E;  1W24 A;  4JI4 E;  2RQL A;  2DRP A;  4LF8 E;  2EQ3 A;  4R8O A;  1IMU A;  2JOX A;  4RHB B;  1XM7 A;  4B3M E;  4LF6 E;  2NA2 A;  2ELZ A;  1QHW A;  2JOG A;  3QFN A;  2E1M A;  2HYO A;  5IT9 C;  1T39 A;  2DMI A;  2V85 A;  2DXL A;  2ENH A;  2WZO A;  4M0V A;  1BBG A;  2CPN A;  2EOY A;  5ADZ A;  2M9A A;  4JI6 E;  2CV9 A;  4JI1 E;  2F4V E;  2LBS B;  2EN4 A;  5A6B A;  1TCO A;  3J81 C;  2WBS A;  3JU0 A;  2H36 X;  4MLQ A;  4Q28 A;  5TSE A;  1DI2 A;  2V87 A;  3J7A G;  1BB8 A;  1TN9 A;  1RQ0 A;  4F6M A;  4R2S A;  3AV0 A;  2CSH A;  3ZU0 A;  5HPE A;  2NUF A;  3QFO A;  1AH5 A;  4HEI A;  4TUI A;  2FGG A;  3H68 A;  4B3S E;  2EN8 A;  2L6M A;  1A1F A;  1YUI A;  2Z72 A;  1PKP A;  2A22 A;  1IBM E;  2EPL X;  1PJT A;  2UU9 E;  2K7I A;  3DJW A;  4LFB E;  4LF4 E;  4ORC A;  1WHQ A;  4BBY A;  3LLH A;  5A6B D;  3EQ1 A;  2UXB E;  5AAS A;  2EMX A;  1WHN A;  2RTX A;  2WCC 3;  1S70 A;  1WAR A;  3J80 C;  2YPN A;  1EH7 A;  4RH8 A;  1TF3 A;  2EMC A;  4NHR A;  4FBQ A;  2WDE A;  4XPN A;  3VHT B;  1X49 A;  5B8I A;  3HXL A;  5KL3 A;  1YFH A;  2EQ0 A;  4NZV A;  2ZO9 B;  1XNQ E;  1S3L A;  2JXP A;  1OID A;  3DW8 C;  2L8T A;  3H67 A;  4G9J A;  3IB8 A;  3AUZ A;  3H60 A;  3DF6 A;  5JPE A;  2KON A;  4KWY A;  1F2I G;  2LTR A;  2NUG A;  3KBP A;  4DV7 E;  3EGH A;  4JI0 E;  4X62 E;  4LF5 E;  4ZYG A;  1X48 A;  4NXN E;  3ZTV A;  5IV8 B;  2GJU A;  5LMN E;  1LLM C;  1SU1 A;  2LJU A;  4FBW A;  2O8A A;  4X8W A;  2L92 A;  1ZR9 A;  2P6B A;  2Z1A A;  2EP3 A;  3KZY A;  4AQY E;  3QFK A;  2EPX A;  4BHC A;  2Z06 A;  4HD0 A;  4GEQ B;  1IT6 A;  4ZYE A;  3RQZ A;  4IJD A;  3F6G A;  4M30 A;  2PRT A;  4Q35 B;  4JV5 E;  2BCD A;  2HY1 A;  2YTD A;  3EPL A;  4WPY A;  2EPC A;  3T1H E;  1J26 A;  2KOU A;  4LTY A;  4DV4 E;  1Z2W A;  3HQ1 A;  1XMO E;  1B69 A;  2N8X A;  1XNR E;  3PSN A;  1V73 A;  2D9H A;  1G2D C;  2I13 A;  2YVT A;  2L2M A;  4Q7F A;  2MC5 A;  4UT3 A;  1PJS A;  2EN6 A;  4F9A B;  5A69 A;  4DT2 A;  2E72 A;  2HHH E;  2DSY A;  1SFE A;  2WDD A;  3ADJ A;  4F54 A;  2EOR A;  1UTE A;  1J5E E;  2JVA A;  4MP0 A;  2WBU A;  4H2B A;  4OR9 A;  1STU A;  3FIG A;  1SR9 A;  4BMJ A;  3HVQ A;  1JK2 A;  2ADR A;  4HTG A;  4R2C A;  2IE3 C;  2JP9 A;  4DV6 E;  3RL4 A;  2V88 A;  3GVE A;  3T1I A;  4WFT A;  1ZBT A;  2EOF A;  2FV4 B;  2V86 A;  5T6J A;  5KL7 A;  3KZZ A;  1UF3 A;  3C6K A;  1XMQ E;  4DR7 E;  4H2G A;  2EZ6 A;  1A1G A;  3DSD A;  1YUJ A;  1YPN A;  3H64 A;  5J28 A;  3OTO E;  4F0Z A;  1O0W A;  1YYO A;  3MSW A;  3MHH C;  4OOG C;  4O43 A;  5KL6 A;  4DR1 E;  4DV2 E;  1FKA E;  2EOJ A;  3BBG A;  4UT3 B;  2LUP B;  2YTN A;  1YSA C;  4L5N C;  2GHF A;  2VQE E;  1N32 E;  2DLQ A;  3E7A A;  2BB8 A;  1NNW A;  3H66 A;  1ZU1 A;  1Z1B A;  1T71 A;  1IQS A;  1WAO 1;  1AAY A;  3J7Y p;  5KL2 A;  3FGA C;  4MOY A;  3IB7 A;  4O24 A;  2A25 A;  1T4L B;  2EMG A;  2EPM X;  1X3C A;  4DV5 E;  3IVE A;  2R76 A;  3RL3 A;  2O8G A;  1GTK A;  4K0K E;  2KKN A;  5A6J A;  4DR3 E;  2F8B A;  2N3H A;  2EOZ A;  2EMH A;  2EOO A;  4MOV A;  3BGH A;  2GLI A;  2EL5 A;  1FJM A;  1M63 A;  4JI3 E;  4UT2 A;  2DIX A;  2DLK A;  2EMY A;  2V8Q B;  2WDC A;  3IWD A;  1A1H A;  2DGC A;  4BC7 A;  5C1V A;  3HPS A;  3IWC A;  4B3R E;  3QFM A;  2EPO A;  2B7T A;  2ODR C;  4FBK A;  2EPU A;  4V0V A;  1RMD A;  4FK5 C;  4YHH E;  1NCS A;  2LV2 A;  2EM0 A;  1KBP A;  4JA7 A;  2ELY A;  2MDR A;  2USH A;  4LFC E;  2EJ4 A;  5A6K A;  5CFF E;  3VYX A;  2NYL C;  2M4I A;  2QFP A;  2V89 A;  4DR5 E;  1KJK A;  2EN3 A;  3HTX A;  1YYK A;  4JI8 E;  2EOE A;  1QFC A;  3ADI A;  2EMZ A;  2YTG A;  2YZT A;  4R2P A;  4DSY A;  1IQO A;  4F2J C;  1S3N A;  1HP1 A;  1G2F C;  4N4R B;  1WJP A;  1UHZ A;  4L8N A;  2YTO A;  4F9C B;  2K4V A;  2EN1 A;  4F9B B;  2YTP A;  2DFJ A;  2EM5 A;  1RC7 A;  4R2D A;  2EMA A;  1BBO A;  1NEI A;  4R2R A;  2YT4 A;  2YSP A;  5IOH A;  2VF1 A;  2R1F A;  1X5W A;  2LT7 A;  3PSO A;  2B7V A;  1I94 E;  2JPA A;  4KKZ A;  2CT1 A;  2Q8U A;  3HPZ A;  2WBT A;  1JK7 A;  2EWL A;  2YRK A;  4FCX A;  1KYQ A;  2DB2 A;  1EH6 A;  3EGG A;  1HPU A;  3ADL A;  2IHR 1;  2R17 A;  2RS6 A;  4H1Y P;  3K6Q A;  2ZOA A;  2L3C A;  1GQE A;  1A1L A;  2EOQ A;  4OX9 E;  2EM6 A;  5F3W A;  4R2A A;  4J6O A;  4X66 E;  5JPF A;  1HNW E;  1U32 A;  4LF9 E;  5INB A;  4R2E A;  4DR4 E;  2VRD A;  4H2F A;  4WXD A;  3JYF A;  4MLV A;  2EOI A;  2KHX A;  4ORB A;  2DMY A;  2YU8 A;  4DUZ E;  2ZM6 E;  1MEY C;  2HC5 A;  2M7Q A;  3P1X A;  1X6E A;  1N36 E;  4LF7 E;  1N33 E;  1II7 A;  2EPP A;  2EPN A;  3C4B A;  2CTD A;  2JY9 A;  4ZX2 A;  5KL5 A;  2EL6 A;  2EOH A;  2YTQ A;  3KWR A;  3ZOQ B;  2RSI A;  4V0X A;  2VE7 C;  1A1J A;  2YU5 A;  1UN6 B;  2BDX A;  1DGC A;  4DUY E;  4IL1 A;  4M9V C;  1S8E A;  1FJG E;  4R2Q A;  2YTE A;  2YEQ A;  5AC4 A;  4JI7 E;  5DNY A;  4JA9 A;  2QFR A;  2HYP A;  4V0W A;  1YYW A;  3IWB A;  4ZYH A;  4YKE A;  2BQ8 X;  2JWO A;  2EMW A;  1A1I A;  2ZBM A;  1X6F A;  3BF2 A;  2LUQ A;  4ORA A;  2EPZ A;  4X9J A;  5A2Q C;  4I5N C;  1N34 E;  4JI5 E;  4GKK E;  2EM3 A;  3E0J A;  2L2N A;  2IAE C;  4DHL A;  4DR2 E;  2ENC A;  1OI8 A;  4M2Z A;  3ECR A;  4DV1 E; 
#chains in the Genus database with same CATH homology
 3ZTV A;  3DSC A;  1MF8 A;  2GJU A;  1KBP A;  4JA7 A;  3P71 C;  3LL8 A;  2USH A;  1SU1 A;  3H63 A;  4I5L C;  2NYL C;  4FBW A;  4H2I A;  2NXF A;  2O8A A;  2QFP A;  4UWQ A;  4TUG A;  2P6B A;  4ZVZ A;  2Z1A A;  4O4K A;  2WDF A;  3QFK A;  3C5W C;  2Z06 A;  1QFC A;  4HD0 A;  3THN A;  1IT6 A;  1T70 A;  4DSY A;  3N5U A;  3RQZ A;  1S3N A;  1HP1 A;  1Z2X A;  2HY1 A;  4O5G A;  2BCD A;  1W24 A;  4LTY A;  1Z2W A;  3PSN A;  2NYM C;  1V73 A;  2DFJ A;  2YVT A;  4LU9 A;  4Q7F A;  1XM7 A;  4UT3 A;  3H62 B;  3IVD A;  3H61 A;  4DT2 A;  5IOH A;  1QHW A;  2QJC A;  2JOG A;  3QFN A;  1S3M A;  3V4Y A;  2WDD A;  2HYO A;  1S95 A;  3PSO A;  1OIE A;  1UTE A;  3RL5 A;  4MP0 A;  1XZW A;  4KKZ A;  2Q8U A;  2DXL A;  2XMO A;  4H2B A;  5GTU A;  4M0V A;  4OR9 A;  1JK7 A;  1HO5 A;  4FCX A;  3EGG A;  1HPU A;  2CV9 A;  2R17 A;  1AUI A;  3HVQ A;  4H1Y P;  4H1S A;  1TCO A;  2IE3 C;  3C9F A;  3RL4 A;  3GVE A;  3T1I A;  5F3W A;  3D03 A;  4J6O A;  5JPF A;  1U32 A;  1UF3 A;  3E7B A;  5INB A;  5JJT A;  3AV0 A;  4H2G A;  4H2F A;  4ORB A;  3ZU0 A;  3QFO A;  3JYF A;  5HPE A;  3K7W C;  3DSD A;  4TUI A;  4KBP A;  4LAC C;  3H64 A;  3H68 A;  5J28 A;  4F0Z A;  2Z72 A;  3K7V C;  2A22 A;  4O43 A;  1II7 A;  4UT3 B;  4ORC A;  4ZX2 A;  3E7A A;  1NNW A;  3H66 A;  1USH A;  2AHD A;  1T71 A;  1S70 A;  1WAR A;  3H69 A;  1WAO 1;  1G5B A;  3FGA C;  2NPP C;  3IB7 A;  4O24 A;  4MOY A;  4V0X A;  4WWL A;  2BDX A;  4IL1 A;  1S8E A;  4FBQ A;  2WDE A;  3ICF A;  2DXN A;  3IVE A;  4XPN A;  3RL3 A;  5B8I A;  2YEQ A;  2O8G A;  2KKN A;  4NZV A;  4JA9 A;  5DNY A;  2QFR A;  2ZO9 B;  4IYP C;  2HYP A;  4V0W A;  1S3L A;  1OID A;  3DW8 C;  4B2O A;  3H67 A;  4G9J A;  2BQ8 X;  4YKE A;  3IB8 A;  4MOV A;  3AUZ A;  5EQV A;  3H60 A;  2ZBM A;  1FJM A;  1M63 A;  5JPE A;  4ORA A;  4UT2 A;  4I5N C;  2WDC A;  3THO B;  2IE4 C;  3CK2 A;  3E0J A;  3TGH A;  3KBP A;  5C1V A;  2IAE C;  3EGH A;  4DHL A;  3QG5 C;  3FLO A;  3QFM A;  4FBK A;  1OI8 A;  4V0V A;  2ZOA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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