4O43A

Dna double-strand break repair pathway choice is directed by distinct mre11 nuclease activities
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
331
structure length
331
Chain Sequence
IHHHHHHVINLKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGNHDWKGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPDESEALRKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAGYAGIEQGREIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNFPGYVRVVYEEDSGILPDLMGEIDNLVKIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities.
pubmed doi rcsb
molecule tags Dna binding protein/inhibitor
source organism Thermotoga maritima
molecule keywords Exonuclease, putative
total genus 96
structure length 331
sequence length 331
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.160.210 Alpha Beta 2-Layer Sandwich Double Stranded RNA Binding Domain DNA double-strand break repair nuclease 4o43A02
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 4o43A01
3C9FA 4ORAA 4TUGA 1TCOA 4DSYA 3TGHA 4OR9A 4JA9A 1W24A 3CK2A 2JOGA 4TUIA 2KKNA 3ZTVA 3H62B 1S3NA 2AHDA 4KBPA 4J6OA 3PSNA 5EQVA 4UT3A 4LU9A 4NZVA 2QFRA 4ORCA 1XZWA 3P71C 4FCXA 3ICFA 3RL3A 4DT2A 2GJUA 2IE3C 4FBQA 3QG5C 3H67A 3QFMA 4IL1A 2Z1AA 4I5LC 3QFNA 1XM7A 2WDFA 4G9JA 1S70A 1WAO1 3KBPA 4UWQA 2NPPC 2IE4C 3AUZA 5F3WA 1JK7A 3THOB 3RL5A 4FBKA 2NYMC 4WWLA 3N5UA 3HVQA 3ZU0A 1OI8A 4H2IA 3RL4A 1WARA 1OIDA 3AV0A 3T1IA 2Z06A 1UF3A 3IVDA 1SU1A 4ORBA 1HO5A 5B8IA 3JYFA 4MP0A 1S3LA 2QJCA 2BQ8X 2WDCA 3H63A 1T71A 2Z72A 3C5WC 5JPEA 1S3MA 3K7VC 2NXFA 3K7WC 1II7A 4ZX2A 2DFJA 1MF8A 5JPFA 4O5GA 4UT2A 3H60A 1AUIA 4UT3B 3PSOA 5C1VA 2WDEA 2USHA 4Q7FA 4ZVZA 1HP1A 3E7BA 3IB7A 1IT6A 4H2GA 1NNWA 4V0XA 2CV9A 3IVEA 5J28A 4IYPC 3H66A 2NYLC 2A22A 4V0VA 3THNA 4H2BA 3IB8A 4FBWA 2R17A 3EGHA 3GVEA 3DSDA 2O8GA 1Z2WA 5JJTA 4M0VA 3H61A 4V0WA 1FJMA 2QFPA 1V73A 3EGGA 1U32A 4B2OA 5DNYA 4H2FA 4H1SA 2BDXA 4I5NC 2Q8UA 4O4KA 4H1YP 1HPUA 1T70A 2BCDA 3V4YA 4MOYA 2HY1A 2HYPA 1KBPA 1M63A 4XPNA 3H64A 4O24A 2O8AA 2IAEC 3DSCA 3DW8C 1S95A 2P6BA 4HD0A 4F0ZA 3H69A 1QFCA 4JA7A 4LACC 1QHWA 1G5BA 4MOVA 3LL8A 4YKEA 1UTEA 3E7AA 3H68A 2YVTA 4LTYA 3RQZA 2WDDA 4O43A 2HYOA 5HPEA 1Z2XA 1S8EA 5INBA 5GTUA 3QFKA 1USHA 1OIEA 3FGAC 3QFOA 2ZBMA 5IOHA 4KKZA 2XMOA 4DHLA
chains in the Genus database with same CATH superfamily
3BBGA 1WRJA 1TCOA 3TGHA 4JI5E 4OR9A 3VYXA 2YTIA 2PRTA 4TUIA 3DJWA 2H36X 3DF6A 1S3NA 2AHDA 4WYQB 3PSNA 4UT3A 2D9HA 2EPPA 3ADGA 2LJUA 1A1GA 4ORCA 2JPAA 2JYAA 3FIGA 3ADLA 3EPLA 2MC6A 3F6GA 2GJUA 2ZOAA 3T1YE 4YHHE 5A6AA 2IE3C 4KZSA 4FBQA 4IL1A 2RS7A 4R2EA 2Z1AA 4I5LC 1ZAAC 4P7DA 1XM7A 1A1JA 1S70A 4F6NA 1NEIA 1WAO1 2NPPC 5F3WA 4WFTA 4ZYDA 1T39A 4FBKA 4WWLA 3RL5A 4OX9E 3N5UA 1OI8A 2NA2A 3AV0A 1GZ6A 2EM0A 4DV0E 2YSOA 2UUCE 2N3HA 5B8IA 2HHHE 3E0JA 2EN1A 3ZOQB 2E5LE 3L00A 2BQ8X 2WDCA 5AASA 2LJHA 2Z72A 5A6JA 2MKDA 4JV5E 2DSYA 2EL5A 2FV4B 5JPFA 4DR2E 4RHBB 4O5GA 5CFFE 2MKNA 2EM4A 2KHXA 3H60A 1UHZA 3LLHA 4BS9A 4I8OA 1X3CA 2F4VE 2KOUA 2KONA 4WSGA 4DR5E 1NNWA 2V88A 4V0XA 3IVEA 4NHRA 2EMBA 2EQ3A 4Q28A 2NYLC 3RMPA 3BF2A 4V0VA 2A25A 3IB8A 2V8QB 5JJTA 2DMYA 4M0VA 3IWCA 2HC5A 3H61A 2YTJA 5AC4A 2QFPA 2CTDA 2NUFA 5DNYA 4H2FA 3HPZA 3J7AG 2DMIA 1HNZE 4Q35B 2UU9E 4WXDA 1T70A 1XMQE 3V4YA 2EL6A 2WZOA 1KBPA 4XPNA 1IQOA 2F8BA 1HNWE 1S95A 2YTGA 2EOQA 4GZNC 4L8NA 5A69A 1PKPA 1BBGA 4B3SE 2VF1A 5KL3A 2M9AA 1P47A 1YUIA 4DR4E 2YVTA 2ZO9B 4ZYHA 2EM5A 2EPMX 2EPKX 5INBA 4GKKE 3J81C 1OIEA 4J8ZA 4KKZA 2EMLA 2EE8A 4B3RE 2EOZA 5A6BD 3D03A 2FTXB 2L2NA 4ORAA 2N3GA 1X6FA 1JK2A 4X9JA 2EN7A 3HPSA 3T1HE 4MLQA 3CK2A 2R1FA 4WSPA 3H62B 4HEIA 2L33A 2CT1A 2EQ0A 4LF4E 2RQLA 4DMIA 1T38A 5IWAE 4WX9A 5EQVA 5KL5A 3M99B 4R03A 4JI0E 2L8TA 1A1HA 4R2CA 2EMZA 2DLQA 2LTRA 4FCXA 2MDGA 4LF9E 3VYYA 2YRKA 4BBYA 4WXCA 2JY9A 3MSWA 3QFMA 2L6MA 4GEQB 4G9JA 2WBTA 3F6HA 3KBPA 2YZTA 1L4SA 1X48A 1B69A 3THOB 2L2KB 3C4BA 4DUYE 2NYMC 2UXDE 2UUAE 3RL4A 1N3GA 2B9DA 2EOFA 1WARA 3T1IA 1UF3A 1I94E 3IVDA 2K7IA 1RMDA 1FJGE 4ORBA 1YUJA 1A1KA 1DI2A 4MP0A 1S3LA 2LO3A 1N33E 2GHFA 1PJQA 4F9BB 2ENAA 4DV2E 1T71A 2EM7A 3MHHC 3BIDA 2VE7C 1YSAC 5AC5A 2EPOA 1II7A 2NXFA 4ZX2A 2EJ4A 4DHLA 2GLIA 3LMLA 5AE1A 4F2JC 2EOYA 4F9CB 2EWLA 2YRMA 1ZR9A 4JI2E 4LFAE 4UT2A 5ADZA 2R76A 1AUIA 4FK5C 3PSOA 2EPXA 5AE2A 2EM3A 1UBDC 3E7BA 3IB7A 1IT6A 1WHQA 2B7TA 2YPNA 2M7QA 2WCC3 4KHPE 3H66A 4R2SA 2V86A 2MDRA 3JAMC 1PDAA 1HNXE 4H2BA 2FGGA 4X62E 2EMCA 2DGCA 2ELZA 3J7Yp 1X5WA 3ADJA 3IWDA 2EORA 2YTQA 2WBSA 2YTNA 2VQFE 2JP9A 4KWYA 1X49A 1KJKA 2EN2A 4H1SA 2LE2A 4O4KA 3VK6A 1YYOA 1IBKE 1EH6A 1HPUA 4JI8E 2BCDA 2BBGA 3VHTB 1M63A 5T6JA 2RSIA 1WXRA 5A2QC 4O24A 3DSCA 3DW8C 2P6BA 3ECRA 1QFCA 4JA7A 2EOOA 4HTGA 1GTKA 1G5BA 4MOVA 1UTEA 1EH7A 4X65E 4AQYE 2EPRA 2YTEA 2E72A 4LTYA 2EN3A 4DKKA 4DR6E 5LMUE 3H68A 2L92A 2VRDA 2WDDA 2HYOA 4ZYGA 1BBOA 1USHA 2E1MA 3FGAC 4F54A 3QFOA 2ZBMA 2ODRD 1Z1BA 2XMOA 2YTOA 2M4IA 3C9FA 1IQSA 2B3TB 3EQ1A 4DSYA 4JA9A 2EP3A 1XNQE 1W24A 2JOGA 3FLOA 2CSHA 2EMYA 2EMHA 1YYKA 4KBPA 2EMAA 5A6BA 2EM6A 1X47A 4NZVA 2QFRA 2YEQA 1XZWA 2JR1A 4JI6E 1NCSA 4JI7E 3ADIA 2EMXA 2ODRC 5KL6A 4DT2A 1ZBQA 4DR1E 1QU6A 1XNRE 2EMFA 4LF6E 4JI4E 5FLXC 2WDFA 4DV7E 4DUZE 2EM2A 2JXPA 4UWQA 1UILA 2IE4C 3AUZA 4K0KE 1JK7A 2LV2A 3ZU0A 1OIDA 2EMKA 4LFCE 5IT9C 3MHSC 1HO5A 2YTFA 4R2DA 1T4NA 3JYFA 5KL2A 2BB8A 2JVAA 2QJCA 5JPEA 1EKZA 3HXLA 3C5WC 5LLQA 3K7VC 2YSPA 2DFJA 1MF8A 2CPNA 5KL4A 5LL6R 1AH5A 4ZYEA 1TF3A 5IV8B 2EOJA 4UT3B 5C1VA 4BHBA 2N8XA 1WHNA 4R2AA 2USHA 4Q7FA 1TF6A 2DXNA 1HP1A 1WJPA 5J28A 4DV5E 2CV9A 4IYPC 1SR9A 1IBME 1HR0E 1YZ9A 2EPNA 2JOBA 3THNA 1UN6B 2R17A 2NUEA 1ZU1A 2V85A 3GVEA 3DSDA 2O8GA 2DIXA 4RH8A 1IBLE 4WPYA 1TN9A 4V0WA 2LRSA 1FJMA 3EGGA 1U32A 4B2OA 2JWOA 3OTOE 2B7VA 1O0WA 4I5NC 4H1YP 4BC7A 4LF5E 3IWBA 4B3ME 2EPCA 3EPJA 2HYPA 2DRPA 4DR7E 2LVHA 5BR8E 3H64A 1SFEA 2ZM6E 2L3CA 3KZZA 2LBSB 4DV6E 1QHWA 4DV1E 4YY3E 1XMOE 1N34E 2GPIA 3LL8A 3J80C 1G2FC 1IMUA 4M2ZA 4F6MA 4M9VC 2NABA 1S8EA 3HTXA 5GTUA 1FKAE 3QFKA 2ELYA 1EH8A 1GQEA 2EOHA 5AE3A 4JI1E 5IOHA 4LF8E 2EN8A 2ADRA 3H09A 4TUGA 1QNTA 2M1SA 2RSMA 4R2RA 2LUQA 1MEYC 2KKNA 5LMNE 3ZTVA 2EPLX 4B3TE 4J6OA 2VQEE 2RTXA 4BC9A 2K4VA 2ENHA 4LU9A 2EMWA 2EPZA 3P71C 2EM8A 3ICFA 3RL3A 1N32E 2RPCA 2YWQA 1T4LB 2UUBE 1J26A 2EOMA 4X8WA 1F2IG 3QG5C 2I9IA 3H67A 2YU5A 3HQ1A 4DR3E 2LMZA 2L2MA 3QFNA 1STUA 2EQ1A 4OOGC 3OMLA 2G7HA 1LLMC 2NUGA 3P1XA 3EPHA 5IXMB 1A1LA 1MGTA 2DLKA 3HVQA 4H2IA 2LCEA 2IHR1 2Z06A 2EMGA 1DGCA 2EOIA 1SU1A 2EZ6A 1JK1A 2EOXA 1RC7A 2V87A 3H63A 4MLVA 5KL7A 4IJDA 1S3MA 2EMIA 4JYAE 3K7WC 4NXNE 1X6EA 2V89A 4LF7E 3C4TA 3UK3C 1J5EE 1YPNA 1BB8A 3K6QA 4NXME 2YTDA 4BMJA 2EPUA 2WDEA 4ZVZA 3C6KA 4H2GA 4BHCA 1N36E 1T4OA 4R8OA 3KWRA 5A6KA 2A22A 2V83A 4P78A 2EOSA 2J7JA 4FBWA 4R2PA 2JOXA 2UXCE 3EGHA 2YTPA 4R2QA 4DV4E 1Z2WA 2EL4A 4M30A 2EM9A 2DB2A 1V73A 4L5NC 3C6MA 1DQ3A 2RS6A 2HGHA 1PJSA 2DXLA 2WBUA 4JI3E 2YU8A 4IS1C 2BDXA 2HJJA 2Q8UA 4X64E 2LTSA 1PJTA 3BGHA 3JTZA 1X6HA 4MOYA 3TQMA 1YYWA 2HY1A 3KZYA 3JU0A 2LT7A 2O8AA 2IAEC 1ZBTA 2EPAA 1A1IA 2EN6A 1AAYA 4HD0A 4F0ZA 3H69A 2YRHA 1G2DC 4LACC 4YKEA 3E7AA 4BCAA 2MC5A 3EPKA 4GKJE 2LUPB 2YT4A 2L3JA 4DV3E 4LFBE 2EN4A 3RQZA 4O43A 1RQ0A 5HPEA 5TSEA 1KYQA 2UXBE 1Z2XA 1A1FA 4N4RB 1YFHA 2I13A 4F9AB 2EOEA 4X66E 2ENCA
chains in the Genus database with same CATH topology
3C9FA 3D03A 4ORAA 4TUGA 1TCOA 4DSYA 3TGHA 4OR9A 4JA9A 1W24A 3CK2A 2JOGA 3FLOA 4TUIA 2KKNA 3ZTVA 3H62B 1S3NA 2AHDA 4KBPA 4J6OA 3PSNA 5EQVA 4UT3A 4LU9A 4NZVA 2QFRA 2YEQA 1XZWA 3P71C 4FCXA 3ICFA 4ORCA 3RL3A 4DT2A 2GJUA 2ZOAA 2IE3C 4FBQA 3QG5C 3H67A 3QFMA 4IL1A 2Z1AA 4I5LC 3QFNA 1XM7A 2WDFA 4G9JA 1S70A 1WAO1 3KBPA 4UWQA 2NPPC 2IE4C 3AUZA 5F3WA 1JK7A 3THOB 3RL5A 4FBKA 2NYMC 4WWLA 3N5UA 3HVQA 3ZU0A 1OI8A 4H2IA 3RL4A 1WARA 1OIDA 3AV0A 3T1IA 2Z06A 1UF3A 3IVDA 1SU1A 4ORBA 1HO5A 5B8IA 3JYFA 4MP0A 3E0JA 1S3LA 2QJCA 2BQ8X 2WDCA 3H63A 1T71A 2Z72A 3C5WC 5JPEA 1S3MA 3K7VC 2NXFA 3K7WC 1II7A 4ZX2A 2DFJA 1MF8A 5JPFA 4O5GA 4UT2A 3H60A 1AUIA 4UT3B 3PSOA 5C1VA 2WDEA 2USHA 4Q7FA 4ZVZA 2DXNA 1HP1A 3E7BA 3IB7A 1IT6A 4H2GA 1NNWA 4V0XA 2CV9A 3IVEA 5J28A 4IYPC 3H66A 2NYLC 2A22A 4V0VA 3THNA 4H2BA 3IB8A 4FBWA 2R17A 3EGHA 3GVEA 3DSDA 2O8GA 1Z2WA 5JJTA 4M0VA 3H61A 4V0WA 1FJMA 2QFPA 1V73A 3EGGA 1U32A 4B2OA 5DNYA 4H2FA 2DXLA 4H1SA 2BDXA 4I5NC 2Q8UA 4O4KA 4H1YP 1HPUA 1T70A 2BCDA 3V4YA 4MOYA 2HY1A 2HYPA 1KBPA 1M63A 4XPNA 3H64A 4O24A 2O8AA 3DSCA 2IAEC 3DW8C 1S95A 2P6BA 4HD0A 4F0ZA 3H69A 1QFCA 4JA7A 4LACC 1QHWA 1G5BA 4MOVA 3LL8A 4YKEA 1UTEA 3E7AA 3H68A 2YVTA 4LTYA 2ZO9B 3RQZA 2WDDA 4O43A 2HYOA 5HPEA 1Z2XA 1S8EA 5INBA 5GTUA 3QFKA 1USHA 1OIEA 3FGAC 3QFOA 2ZBMA 5IOHA 4KKZA 2XMOA 4DHLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3C9F A;  4ORA A;  4TUG A;  1TCO A;  4DSY A;  3TGH A;  4OR9 A;  4JA9 A;  1W24 A;  3CK2 A;  2JOG A;  4TUI A;  2KKN A;  3ZTV A;  3H62 B;  1S3N A;  2AHD A;  4KBP A;  4J6O A;  3PSN A;  5EQV A;  4UT3 A;  4LU9 A;  4NZV A;  2QFR A;  4ORC A;  1XZW A;  3P71 C;  4FCX A;  3ICF A;  3RL3 A;  4DT2 A;  2GJU A;  2IE3 C;  4FBQ A;  3QG5 C;  3H67 A;  3QFM A;  4IL1 A;  2Z1A A;  4I5L C;  3QFN A;  1XM7 A;  2WDF A;  4G9J A;  1S70 A;  1WAO 1;  3KBP A;  4UWQ A;  2NPP C;  2IE4 C;  3AUZ A;  5F3W A;  1JK7 A;  3THO B;  3RL5 A;  4FBK A;  2NYM C;  4WWL A;  3N5U A;  3HVQ A;  3ZU0 A;  1OI8 A;  4H2I A;  3RL4 A;  1WAR A;  1OID A;  3AV0 A;  3T1I A;  2Z06 A;  1UF3 A;  3IVD A;  1SU1 A;  4ORB A;  1HO5 A;  5B8I A;  3JYF A;  4MP0 A;  1S3L A;  2QJC A;  2BQ8 X;  2WDC A;  3H63 A;  1T71 A;  2Z72 A;  3C5W C;  5JPE A;  1S3M A;  3K7V C;  2NXF A;  3K7W C;  1II7 A;  4ZX2 A;  2DFJ A;  1MF8 A;  5JPF A;  4O5G A;  4UT2 A;  3H60 A;  1AUI A;  4UT3 B;  3PSO A;  5C1V A;  2WDE A;  2USH A;  4Q7F A;  4ZVZ A;  1HP1 A;  3E7B A;  3IB7 A;  1IT6 A;  4H2G A;  1NNW A;  4V0X A;  2CV9 A;  3IVE A;  5J28 A;  4IYP C;  3H66 A;  2NYL C;  2A22 A;  4V0V A;  3THN A;  4H2B A;  3IB8 A;  4FBW A;  2R17 A;  3EGH A;  3GVE A;  3DSD A;  2O8G A;  1Z2W A;  5JJT A;  4M0V A;  3H61 A;  4V0W A;  1FJM A;  2QFP A;  1V73 A;  3EGG A;  1U32 A;  4B2O A;  5DNY A;  4H2F A;  4H1S A;  2BDX A;  4I5N C;  2Q8U A;  4O4K A;  4H1Y P;  1HPU A;  1T70 A;  2BCD A;  3V4Y A;  4MOY A;  2HY1 A;  2HYP A;  1KBP A;  1M63 A;  4XPN A;  3H64 A;  4O24 A;  2O8A A;  2IAE C;  3DSC A;  3DW8 C;  1S95 A;  2P6B A;  4HD0 A;  4F0Z A;  3H69 A;  1QFC A;  4JA7 A;  4LAC C;  1QHW A;  1G5B A;  4MOV A;  3LL8 A;  4YKE A;  1UTE A;  3E7A A;  3H68 A;  2YVT A;  4LTY A;  3RQZ A;  2WDD A;  4O43 A;  2HYO A;  5HPE A;  1Z2X A;  1S8E A;  5INB A;  5GTU A;  3QFK A;  1USH A;  1OIE A;  3FGA C;  3QFO A;  2ZBM A;  5IOH A;  4KKZ A;  2XMO A;  4DHL A; 
#chains in the Genus database with same CATH topology
 3BBG A;  1WRJ A;  1TCO A;  3TGH A;  4JI5 E;  4OR9 A;  3VYX A;  2YTI A;  2PRT A;  4TUI A;  3DJW A;  2H36 X;  3DF6 A;  1S3N A;  2AHD A;  4WYQ B;  3PSN A;  4UT3 A;  2D9H A;  2EPP A;  3ADG A;  2LJU A;  1A1G A;  4ORC A;  2JPA A;  2JYA A;  3FIG A;  3ADL A;  3EPL A;  2MC6 A;  3F6G A;  2GJU A;  2ZOA A;  3T1Y E;  4YHH E;  5A6A A;  2IE3 C;  4KZS A;  4FBQ A;  4IL1 A;  2RS7 A;  4R2E A;  2Z1A A;  4I5L C;  1ZAA C;  4P7D A;  1XM7 A;  1A1J A;  1S70 A;  4F6N A;  1NEI A;  1WAO 1;  2NPP C;  5F3W A;  4WFT A;  4ZYD A;  1T39 A;  4FBK A;  4WWL A;  3RL5 A;  4OX9 E;  3N5U A;  1OI8 A;  2NA2 A;  3AV0 A;  1GZ6 A;  2EM0 A;  4DV0 E;  2YSO A;  2UUC E;  2N3H A;  5B8I A;  2HHH E;  3E0J A;  2EN1 A;  3ZOQ B;  2E5L E;  3L00 A;  2BQ8 X;  2WDC A;  5AAS A;  2LJH A;  2Z72 A;  5A6J A;  2MKD A;  4JV5 E;  2DSY A;  2EL5 A;  2FV4 B;  5JPF A;  4DR2 E;  4RHB B;  4O5G A;  5CFF E;  2MKN A;  2EM4 A;  2KHX A;  3H60 A;  1UHZ A;  3LLH A;  4BS9 A;  4I8O A;  1X3C A;  2F4V E;  2KOU A;  2KON A;  4WSG A;  4DR5 E;  1NNW A;  2V88 A;  4V0X A;  3IVE A;  4NHR A;  2EMB A;  2EQ3 A;  4Q28 A;  2NYL C;  3RMP A;  3BF2 A;  4V0V A;  2A25 A;  3IB8 A;  2V8Q B;  5JJT A;  2DMY A;  4M0V A;  3IWC A;  2HC5 A;  3H61 A;  2YTJ A;  5AC4 A;  2QFP A;  2CTD A;  2NUF A;  5DNY A;  4H2F A;  3HPZ A;  3J7A G;  2DMI A;  1HNZ E;  4Q35 B;  2UU9 E;  4WXD A;  1T70 A;  1XMQ E;  3V4Y A;  2EL6 A;  2WZO A;  1KBP A;  4XPN A;  1IQO A;  2F8B A;  1HNW E;  1S95 A;  2YTG A;  2EOQ A;  4GZN C;  4L8N A;  5A69 A;  1PKP A;  1BBG A;  4B3S E;  2VF1 A;  5KL3 A;  2M9A A;  1P47 A;  1YUI A;  4DR4 E;  2YVT A;  2ZO9 B;  4ZYH A;  2EM5 A;  2EPM X;  2EPK X;  5INB A;  4GKK E;  3J81 C;  1OIE A;  4J8Z A;  4KKZ A;  2EML A;  2EE8 A;  4B3R E;  2EOZ A;  5A6B D;  3D03 A;  2FTX B;  2L2N A;  4ORA A;  2N3G A;  1X6F A;  1JK2 A;  4X9J A;  2EN7 A;  3HPS A;  3T1H E;  4MLQ A;  3CK2 A;  2R1F A;  4WSP A;  3H62 B;  4HEI A;  2L33 A;  2CT1 A;  2EQ0 A;  4LF4 E;  2RQL A;  4DMI A;  1T38 A;  5IWA E;  4WX9 A;  5EQV A;  5KL5 A;  3M99 B;  4R03 A;  4JI0 E;  2L8T A;  1A1H A;  4R2C A;  2EMZ A;  2DLQ A;  2LTR A;  4FCX A;  2MDG A;  4LF9 E;  3VYY A;  2YRK A;  4BBY A;  4WXC A;  2JY9 A;  3MSW A;  3QFM A;  2L6M A;  4GEQ B;  4G9J A;  2WBT A;  3F6H A;  3KBP A;  2YZT A;  1L4S A;  1X48 A;  1B69 A;  3THO B;  2L2K B;  3C4B A;  4DUY E;  2NYM C;  2UXD E;  2UUA E;  3RL4 A;  1N3G A;  2B9D A;  2EOF A;  1WAR A;  3T1I A;  1UF3 A;  1I94 E;  3IVD A;  2K7I A;  1RMD A;  1FJG E;  4ORB A;  1YUJ A;  1A1K A;  1DI2 A;  4MP0 A;  1S3L A;  2LO3 A;  1N33 E;  2GHF A;  1PJQ A;  4F9B B;  2ENA A;  4DV2 E;  1T71 A;  2EM7 A;  3MHH C;  3BID A;  2VE7 C;  1YSA C;  5AC5 A;  2EPO A;  1II7 A;  2NXF A;  4ZX2 A;  2EJ4 A;  4DHL A;  2GLI A;  3LML A;  5AE1 A;  4F2J C;  2EOY A;  4F9C B;  2EWL A;  2YRM A;  1ZR9 A;  4JI2 E;  4LFA E;  4UT2 A;  5ADZ A;  2R76 A;  1AUI A;  4FK5 C;  3PSO A;  2EPX A;  5AE2 A;  2EM3 A;  1UBD C;  3E7B A;  3IB7 A;  1IT6 A;  1WHQ A;  2B7T A;  2YPN A;  2M7Q A;  2WCC 3;  4KHP E;  3H66 A;  4R2S A;  2V86 A;  2MDR A;  3JAM C;  1PDA A;  1HNX E;  4H2B A;  2FGG A;  4X62 E;  2EMC A;  2DGC A;  2ELZ A;  3J7Y p;  1X5W A;  3ADJ A;  3IWD A;  2EOR A;  2YTQ A;  2WBS A;  2YTN A;  2VQF E;  2JP9 A;  4KWY A;  1X49 A;  1KJK A;  2EN2 A;  4H1S A;  2LE2 A;  4O4K A;  3VK6 A;  1YYO A;  1IBK E;  1EH6 A;  1HPU A;  4JI8 E;  2BCD A;  2BBG A;  3VHT B;  1M63 A;  5T6J A;  2RSI A;  1WXR A;  5A2Q C;  4O24 A;  3DSC A;  3DW8 C;  2P6B A;  3ECR A;  1QFC A;  4JA7 A;  2EOO A;  4HTG A;  1GTK A;  1G5B A;  4MOV A;  1UTE A;  1EH7 A;  4X65 E;  4AQY E;  2EPR A;  2YTE A;  2E72 A;  4LTY A;  2EN3 A;  4DKK A;  4DR6 E;  5LMU E;  3H68 A;  2L92 A;  2VRD A;  2WDD A;  2HYO A;  4ZYG A;  1BBO A;  1USH A;  2E1M A;  3FGA C;  4F54 A;  3QFO A;  2ZBM A;  2ODR D;  1Z1B A;  2XMO A;  2YTO A;  2M4I A;  3C9F A;  1IQS A;  2B3T B;  3EQ1 A;  4DSY A;  4JA9 A;  2EP3 A;  1XNQ E;  1W24 A;  2JOG A;  3FLO A;  2CSH A;  2EMY A;  2EMH A;  1YYK A;  4KBP A;  2EMA A;  5A6B A;  2EM6 A;  1X47 A;  4NZV A;  2QFR A;  2YEQ A;  1XZW A;  2JR1 A;  4JI6 E;  1NCS A;  4JI7 E;  3ADI A;  2EMX A;  2ODR C;  5KL6 A;  4DT2 A;  1ZBQ A;  4DR1 E;  1QU6 A;  1XNR E;  2EMF A;  4LF6 E;  4JI4 E;  5FLX C;  2WDF A;  4DV7 E;  4DUZ E;  2EM2 A;  2JXP A;  4UWQ A;  1UIL A;  2IE4 C;  3AUZ A;  4K0K E;  1JK7 A;  2LV2 A;  3ZU0 A;  1OID A;  2EMK A;  4LFC E;  5IT9 C;  3MHS C;  1HO5 A;  2YTF A;  4R2D A;  1T4N A;  3JYF A;  5KL2 A;  2BB8 A;  2JVA A;  2QJC A;  5JPE A;  1EKZ A;  3HXL A;  3C5W C;  5LLQ A;  3K7V C;  2YSP A;  2DFJ A;  1MF8 A;  2CPN A;  5KL4 A;  5LL6 R;  1AH5 A;  4ZYE A;  1TF3 A;  5IV8 B;  2EOJ A;  4UT3 B;  5C1V A;  4BHB A;  2N8X A;  1WHN A;  4R2A A;  2USH A;  4Q7F A;  1TF6 A;  2DXN A;  1HP1 A;  1WJP A;  5J28 A;  4DV5 E;  2CV9 A;  4IYP C;  1SR9 A;  1IBM E;  1HR0 E;  1YZ9 A;  2EPN A;  2JOB A;  3THN A;  1UN6 B;  2R17 A;  2NUE A;  1ZU1 A;  2V85 A;  3GVE A;  3DSD A;  2O8G A;  2DIX A;  4RH8 A;  1IBL E;  4WPY A;  1TN9 A;  4V0W A;  2LRS A;  1FJM A;  3EGG A;  1U32 A;  4B2O A;  2JWO A;  3OTO E;  2B7V A;  1O0W A;  4I5N C;  4H1Y P;  4BC7 A;  4LF5 E;  3IWB A;  4B3M E;  2EPC A;  3EPJ A;  2HYP A;  2DRP A;  4DR7 E;  2LVH A;  5BR8 E;  3H64 A;  1SFE A;  2ZM6 E;  2L3C A;  3KZZ A;  2LBS B;  4DV6 E;  1QHW A;  4DV1 E;  4YY3 E;  1XMO E;  1N34 E;  2GPI A;  3LL8 A;  3J80 C;  1G2F C;  1IMU A;  4M2Z A;  4F6M A;  4M9V C;  2NAB A;  1S8E A;  3HTX A;  5GTU A;  1FKA E;  3QFK A;  2ELY A;  1EH8 A;  1GQE A;  2EOH A;  5AE3 A;  4JI1 E;  5IOH A;  4LF8 E;  2EN8 A;  2ADR A;  3H09 A;  4TUG A;  1QNT A;  2M1S A;  2RSM A;  4R2R A;  2LUQ A;  1MEY C;  2KKN A;  5LMN E;  3ZTV A;  2EPL X;  4B3T E;  4J6O A;  2VQE E;  2RTX A;  4BC9 A;  2K4V A;  2ENH A;  4LU9 A;  2EMW A;  2EPZ A;  3P71 C;  2EM8 A;  3ICF A;  3RL3 A;  1N32 E;  2RPC A;  2YWQ A;  1T4L B;  2UUB E;  1J26 A;  2EOM A;  4X8W A;  1F2I G;  3QG5 C;  2I9I A;  3H67 A;  2YU5 A;  3HQ1 A;  4DR3 E;  2LMZ A;  2L2M A;  3QFN A;  1STU A;  2EQ1 A;  4OOG C;  3OML A;  2G7H A;  1LLM C;  2NUG A;  3P1X A;  3EPH A;  5IXM B;  1A1L A;  1MGT A;  2DLK A;  3HVQ A;  4H2I A;  2LCE A;  2IHR 1;  2Z06 A;  2EMG A;  1DGC A;  2EOI A;  1SU1 A;  2EZ6 A;  1JK1 A;  2EOX A;  1RC7 A;  2V87 A;  3H63 A;  4MLV A;  5KL7 A;  4IJD A;  1S3M A;  2EMI A;  4JYA E;  3K7W C;  4NXN E;  1X6E A;  2V89 A;  4LF7 E;  3C4T A;  3UK3 C;  1J5E E;  1YPN A;  1BB8 A;  3K6Q A;  4NXM E;  2YTD A;  4BMJ A;  2EPU A;  2WDE A;  4ZVZ A;  3C6K A;  4H2G A;  4BHC A;  1N36 E;  1T4O A;  4R8O A;  3KWR A;  5A6K A;  2A22 A;  2V83 A;  4P78 A;  2EOS A;  2J7J A;  4FBW A;  4R2P A;  2JOX A;  2UXC E;  3EGH A;  2YTP A;  4R2Q A;  4DV4 E;  1Z2W A;  2EL4 A;  4M30 A;  2EM9 A;  2DB2 A;  1V73 A;  4L5N C;  3C6M A;  1DQ3 A;  2RS6 A;  2HGH A;  1PJS A;  2DXL A;  2WBU A;  4JI3 E;  2YU8 A;  4IS1 C;  2BDX A;  2HJJ A;  2Q8U A;  4X64 E;  2LTS A;  1PJT A;  3BGH A;  3JTZ A;  1X6H A;  4MOY A;  3TQM A;  1YYW A;  2HY1 A;  3KZY A;  3JU0 A;  2LT7 A;  2O8A A;  2IAE C;  1ZBT A;  2EPA A;  1A1I A;  2EN6 A;  1AAY A;  4HD0 A;  4F0Z A;  3H69 A;  2YRH A;  1G2D C;  4LAC C;  4YKE A;  3E7A A;  4BCA A;  2MC5 A;  3EPK A;  4GKJ E;  2LUP B;  2YT4 A;  2L3J A;  4DV3 E;  4LFB E;  2EN4 A;  3RQZ A;  4O43 A;  1RQ0 A;  5HPE A;  5TSE A;  1KYQ A;  2UXB E;  1Z2X A;  1A1F A;  4N4R B;  1YFH A;  2I13 A;  4F9A B;  2EOE A;  4X66 E;  2ENC A; 
#chains in the Genus database with same CATH homology
 3C9F A;  3D03 A;  4ORA A;  4TUG A;  1TCO A;  4DSY A;  3TGH A;  4OR9 A;  4JA9 A;  1W24 A;  3CK2 A;  2JOG A;  3FLO A;  4TUI A;  2KKN A;  3ZTV A;  3H62 B;  1S3N A;  2AHD A;  4KBP A;  4J6O A;  3PSN A;  5EQV A;  4UT3 A;  4LU9 A;  4NZV A;  2QFR A;  2YEQ A;  1XZW A;  3P71 C;  4FCX A;  3ICF A;  4ORC A;  3RL3 A;  4DT2 A;  2GJU A;  2ZOA A;  2IE3 C;  4FBQ A;  3QG5 C;  3H67 A;  3QFM A;  4IL1 A;  2Z1A A;  4I5L C;  3QFN A;  1XM7 A;  2WDF A;  4G9J A;  1S70 A;  1WAO 1;  3KBP A;  4UWQ A;  2NPP C;  2IE4 C;  3AUZ A;  5F3W A;  1JK7 A;  3THO B;  3RL5 A;  4FBK A;  2NYM C;  4WWL A;  3N5U A;  3HVQ A;  3ZU0 A;  1OI8 A;  4H2I A;  3RL4 A;  1WAR A;  1OID A;  3AV0 A;  3T1I A;  2Z06 A;  1UF3 A;  3IVD A;  1SU1 A;  4ORB A;  1HO5 A;  5B8I A;  3JYF A;  4MP0 A;  3E0J A;  1S3L A;  2QJC A;  2BQ8 X;  2WDC A;  3H63 A;  1T71 A;  2Z72 A;  3C5W C;  5JPE A;  1S3M A;  3K7V C;  2NXF A;  3K7W C;  1II7 A;  4ZX2 A;  2DFJ A;  1MF8 A;  5JPF A;  4O5G A;  4UT2 A;  3H60 A;  1AUI A;  4UT3 B;  3PSO A;  5C1V A;  2WDE A;  2USH A;  4Q7F A;  4ZVZ A;  2DXN A;  1HP1 A;  3E7B A;  3IB7 A;  1IT6 A;  4H2G A;  1NNW A;  4V0X A;  2CV9 A;  3IVE A;  5J28 A;  4IYP C;  3H66 A;  2NYL C;  2A22 A;  4V0V A;  3THN A;  4H2B A;  3IB8 A;  4FBW A;  2R17 A;  3EGH A;  3GVE A;  3DSD A;  2O8G A;  1Z2W A;  5JJT A;  4M0V A;  3H61 A;  4V0W A;  1FJM A;  2QFP A;  1V73 A;  3EGG A;  1U32 A;  4B2O A;  5DNY A;  4H2F A;  2DXL A;  4H1S A;  2BDX A;  4I5N C;  2Q8U A;  4O4K A;  4H1Y P;  1HPU A;  1T70 A;  2BCD A;  3V4Y A;  4MOY A;  2HY1 A;  2HYP A;  1KBP A;  1M63 A;  4XPN A;  3H64 A;  4O24 A;  2O8A A;  3DSC A;  2IAE C;  3DW8 C;  1S95 A;  2P6B A;  4HD0 A;  4F0Z A;  3H69 A;  1QFC A;  4JA7 A;  4LAC C;  1QHW A;  1G5B A;  4MOV A;  3LL8 A;  4YKE A;  1UTE A;  3E7A A;  3H68 A;  2YVT A;  4LTY A;  2ZO9 B;  3RQZ A;  2WDD A;  4O43 A;  2HYO A;  5HPE A;  1Z2X A;  1S8E A;  5INB A;  5GTU A;  3QFK A;  1USH A;  1OIE A;  3FGA C;  3QFO A;  2ZBM A;  5IOH A;  4KKZ A;  2XMO A;  4DHL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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