4O43 | Genus

Total Genus 96

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	96
sequence length	331
structure length	331
Chain Sequence	IHHHHHHVINLKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGNHDWKGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPDESEALRKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAGYAGIEQGREIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNFPGYVRVVYEEDSGILPDLMGEIDNLVKIE

Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__066994884204083__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__066994884204083__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://genus.fuw.edu.pl/view/4O43/A/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__066994884204083__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"066994884204083","bgcolor":"white" }

setting document base to "https://genus.fuw.edu.pl/view/4O43/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__066994884204083__ ready

script 1 started

platformSpeed = 8

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Dna binding protein/inhibitor
source organism	Thermotoga maritima
publication title	DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities. pubmed doi rcsb
molecule keywords	Exonuclease, putative
total genus	96
structure length	331
sequence length	331
chains with identical sequence	B
ec nomenclature
pdb deposition date	2013-12-18

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00149	Metallophos	Calcineurin-like phosphoesterase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.160.210	Alpha Beta	2-Layer Sandwich	Double Stranded RNA Binding Domain	DNA double-strand break repair nuclease	4o43A02
3.60.21.10	Alpha Beta	4-Layer Sandwich	Purple Acid Phosphatase; chain A, domain 2	Purple Acid Phosphatase; chain A, domain 2	4o43A01

4H2IA 4UT3B 2BCDA 3QFKA 4Q7FA 4WWLA 4KBPA 4LTYA 4ZX2A 3AUZA 4FBQA 2HYOA 5IOHA 4FCXA 4FBWA 1JK7A 4TUGA 3PSOA 4V0XA 2Z06A 4O5GA 1UF3A 3TGHA 3H66A 1UTEA 1AUIA 3IB7A 2IE4C 1II7A 4H2GA 1Z2XA 4MOVA 4DSYA 2CV9A 2Z1AA 4UT3A 4M0VA 2WDFA 4B2OA 5J28A 1QHWA 3JYFA 3LL8A 1HO5A 1V73A 3KBPA 4G9JA 4MOYA 3DSCA 1SU1A 1HPUA 2GJUA 4LU9A 3ZTVA 4XPNA 4HD0A 4I5NC 4O4KA 2BQ8X 4ORAA 2AHDA 1NNWA 3THNA 3HVQA 4DHLA 3H68A 4TUIA 2NYMC 1OIDA 3DSDA 4UT2A 1S3LA 3GVEA 4LACC 2O8GA 2QFRA 4FBKA 4OR9A 4NZVA 4J6OA 2Z72A 4IL1A 3H69A 3E7AA 1W24A 4MP0A 3H64A 4V0VA 3EGGA 2BDXA 5JPEA 2QFPA 4I5LC 4F0ZA 5INBA 5GTUA 1WARA 2O8AA 5DNYA 4JA7A 2A22A 5JPFA 1G5BA 3QG5C 1S95A 1MF8A 4O24A 3C5WC 3V4YA 1M63A 3ZU0A 5EQVA 1FJMA 3QFMA 3CK2A 4KKZA 3RL4A 4O43A 2DFJA 3P71C 3IB8A 2IAEC 2NYLC 5B8IA 3T1IA 3RQZA 4H2BA 2XMOA 5JJTA 2WDCA 1Z2WA 2YVTA 1QFCA 2QJCA 3DW8C 3H67A 3H63A 1U32A 3AV0A 3PSNA 1WAO1 2JOGA 4H2FA 2R17A 1S3NA 4JA9A 1S8EA 2NXFA 1XM7A 4DT2A 3E7BA 4IYPC 3N5UA 3C9FA 4ORBA 2IE3C 2USHA 5C1VA 3IVDA 2WDEA 1T70A 3K7WC 4H1YP 1KBPA 2HY1A 2ZBMA 4ORCA 2P6BA 3FGAC 3IVEA 3QFOA 4H1SA 3H62B 4YKEA 3RL5A 4UWQA 5HPEA 3H61A 1IT6A 3THOB 2KKNA 1TCOA 3RL3A 5F3WA 2NPPC 1T71A 1USHA 3EGHA 1OI8A 1HP1A 2Q8UA 3QFNA 1S70A 3H60A 2HYPA 4V0WA 1OIEA 4ZVZA 2WDDA 3ICFA 1XZWA 1S3MA 3K7VC
chains in the Genus database with same CATH superfamily

2YWQA 5LLQA 2BCDA 4L8NA 5IT9C 4Q7FA 4JI8E 1IBLE 2EOQA 2EMYA 4ZX2A 3J80C 3AUZA 3HXLA 2HYOA 2KOUA 4V0XA 4M9VC 3H66A 1AUIA 4BC9A 2DB2A 2LUPB 1RMDA 3JU0A 1HNZE 4H2GA 2K7IA 4DUYE 4MOVA 2J7JA 2YRKA 3IWCA 5KL6A 4B2OA 5J28A 4HTGA 1QHWA 1HO5A 1V73A 2DMIA 4DV7E 3KBPA 4G9JA 3C4TA 5AC5A 4JI6E 1HPUA 3C4BA 4LU9A 3C6KA 2DLKA 2ENHA 4F6MA 5AE2A 4O4KA 1F2IG 4HD0A 2AHDA 3VYXA 2FTXB 1NNWA 3K6QA 3LLHA 3VYYA 3F6HA 2KHXA 4UT2A 2EN2A 1S3LA 3GVEA 5A6KA 2O8GA 2EN1A 4NXME 2QFRA 4FBKA 5A2QC 1EH7A 4IL1A 3E7AA 2CSHA 2YSOA 2EM2A 2YTNA 4M30A 3EGGA 4ZYDA 2F4VE 3ADLA 2EMLA 2JWOA 2WCC3 4F0ZA 4I5LC 5DNYA 3RMPA 5JPFA 1YYOA 2EOIA 5KL3A 4O24A 2EPLX 2YTDA 5EQVA 2UXBE 1ZBTA 2DFJA 1JK2A 4GZNC 2LO3A 3MHHC 2IAEC 5B8IA 4KWYA 2L3JA 3HQ1A 2JVAA 5JJTA 4RH8A 2EMXA 4DV5E 2ADRA 2YVTA 4JI7E 3T1HE 2EPRA 4M2ZA 1QFCA 3H67A 1EKZA 1X3CA 1KYQA 1U32A 3PSNA 4WX9A 1S8EA 2LTRA 2LMZA 5IXMB 2PRTA 4DT2A 2EOJA 1HR0E 2EQ0A 4ORBA 1A1GA 1STUA 2B9DA 4BCAA 2IE3C 4ZYGA 3IVDA 2M7QA 2ELYA 1YPNA 2EN3A 2EOXA 4F9AB 3P1XA 2EMHA 4ORCA 5KL4A 2LVHA 3IVEA 3QFOA 3HPZA 4YY3E 1DI2A 2YRMA 1MEYC 5HPEA 4LFBE 1HNWE 2YU5A 5F3WA 2VF1A 2EPZA 2NPPC 3ZOQB 4R2DA 3EGHA 2BB8A 2EMFA 1OI8A 2EN8A 4DKKA 4V0WA 5A6BD 4P78A 4DR2E 2A25A 4B3TE 4R2EA 1XZWA 4JI1E 1FJGE 2EPKX 2EPUA 2FGGA 3MHSC 4WWLA 4F9CB 2NA2A 5FLXC 1WJPA 2BBGA 5IOHA 5IV8B 2RS6A 4TUGA 1BBGA 1B69A 2EL4A 3BGHA 4NHRA 3PSOA 2Z06A 4O5GA 2L3CA 2YTOA 2ZO9B 3IB7A 2EM3A 2EM6A 2L8TA 3HTXA 2IE4C 2KONA 1II7A 1Z2XA 2CV9A 2Z1AA 1BBOA 4JI2E 1AAYA 2JPAA 4F2JC 3DSCA 4R2SA 2UXDE 1SU1A 2EORA 2EE8A 2IHR1 4HEIA 4Q35B 2EM7A 1TN9A 4XPNA 2L2KB 2EOMA 2DSYA 5T6JA 4B3RE 4ORAA 3THNA 1PKPA 2EPOA 2RQLA 4DHLA 2YTJA 4LF8E 4DV6E 2NYMC 3ADJA 2UUBE 4OX9E 2ENAA 1A1HA 1LLMC 2MKNA 4JV5E 1GTKA 2JY9A 2LV2A 4NZVA 1TF3A 2V86A 4F9BB 2EQ1A 3H69A 4MP0A 2VQEE 5A6AA 2BDXA 5JPEA 2DXNA 1YUIA 4BS9A 2QFPA 1WARA 1Z1BA 1A1IA 2A22A 1G5BA 4DV2E 4BHCA 4BBYA 1S95A 2L2MA 2RTXA 2EPMX 3C5WC 1M63A 2L6MA 3JTZA 4WXDA 2EPXA 3CK2A 3RL4A 4O43A 3HPSA 2EOSA 1L4SA 1YSAC 2L2NA 4LF6E 2E1MA 5LMNE 3RQZA 4H2BA 4P7DA 2I9IA 4K0KE 2YZTA 1X49A 2DGCA 1YZ9A 2QJCA 3MSWA 3H63A 3JAMC 3AV0A 4B3ME 1ZU1A 4H2FA 1BB8A 4WFTA 1S3NA 4JA9A 4DR1E 5BR8E 1PDAA 1HNXE 3BF2A 3KZZA 3EPHA 4IYPC 2M1SA 3C9FA 3LMLA 2USHA 5C1VA 2JR1A 1T70A 5ADZA 3K7WC 2WBTA 2YU8A 1KBPA 3EPKA 2ODRD 2YRHA 1YYWA 2EOHA 4LF7E 3H62B 4R2CA 4UWQA 2EPAA 3H61A 5LL6R 1IT6A 2N3HA 2DRPA 2RSMA 2EM8A 5KL2A 1G2DC 1USHA 1AH5A 2E72A 4DR5E 1X48A 2Q8UA 2DIXA 1S70A 4DUZE 3H60A 2HYPA 3VK6A 2EMBA 2NABA 1N34E 2WDDA 1S3MA 3K7VC 2NUFA 1T4NA 4DR4E 1FKAE 2R1FA 2L92A 2VE7C 4LTYA 4DMIA 2EOEA 4KBPA 2EL6A 4X65E 2YEQA 2DXLA 1ZBQA 2EN6A 1JK7A 1N3GA 2LCEA 3TGHA 2EOYA 1EH8A 1UBDC 1UTEA 1IBKE 2EM5A 4BMJA 4X9JA 4F6NA 2E5LE 1N33E 1J26A 5A6JA 2EPPA 3L00A 2EMAA 2EM4A 4UT3A 1UN6B 2EJ4A 4DSYA 2LE2A 2EN4A 4R2RA 2UU9E 2JYAA 2MKDA 5AE1A 3EPLA 3ADGA 1WHNA 3FLOA 4OOGC 4JI3E 1IQSA 2EPCA 1YFHA 2GJUA 1WRJA 4DV1E 2YTGA 1N36E 4MLQA 1PJSA 4F54A 5AE3A 2YT4A 2BQ8X 2N3GA 2YTQA 2HC5A 4TUIA 1OIDA 3DSDA 2EZ6A 1RQ0A 4LACC 4DV4E 2UUCE 1XNQE 4WXCA 2V83A 5A6BA 2RSIA 1G2FC 3J7AG 1SR9A 5KL5A 1W24A 1X5WA 2V85A 2YTPA 1WXRA 4V0VA 2M4IA 1XMOE 1GQEA 1NCSA 3F6GA 2YTEA 2NUEA 4ZYEA 2ZOAA 5INBA 5GTUA 4JA7A 1TF6A 1X6FA 4WYQB 2V8QB 4DR6E 3QG5C 3OTOE 2ZM6E 3T1YE 3E0JA 3ZU0A 1RC7A 3VHTB 1UILA 2HGHA 1KJKA 1FJMA 2LJUA 3QFMA 4KKZA 2VRDA 3IB8A 2B7TA 3IWDA 2EMKA 2H36X 4X62E 2XMOA 4JI0E 2YSPA 2LJHA 2MDRA 2YTIA 2CPNA 2VQFE 1A1FA 1WAO1 2JOGA 2R17A 1UHZA 4R2PA 4IS1C 4Q28A 1T38A 1XM7A 2NXFA 1JK1A 4DR7E 1YUJA 3E7BA 3D03A 2EOOA 1YYKA 2WDEA 2JP9A 1X6HA 4FK5C 4WSPA 4R8OA 2EMCA 2ZBMA 2EMGA 2P6BA 4H1SA 2HJJA 1A1JA 2EWLA 1PJTA 3DF6A 2YPNA 1N32E 2EM0A 1T39A 3RL3A 2GLIA 1QNTA 3IWBA 3M99B 1T71A 2ENCA 2WBSA 5CFFE 1HP1A 2G7HA 3QFNA 2CTDA 4RHBB 4X66E 3BBGA 3J7Yp 4J8ZA 3EQ1A 2FV4B 3ICFA 4H2IA 4UT3B 2V87A 4DV0E 3QFKA 4ZYHA 1IQOA 5AASA 4FBQA 1QU6A 1ZR9A 2LUQA 3FIGA 4FCXA 5A69A 2EP3A 4FBWA 1MGTA 3ADIA 1UF3A 2EMIA 1O0WA 2MC5A 3C6MA 5AC4A 2WZOA 4LF4E 2B7VA 4M0VA 4LFAE 2WDFA 4JI5E 3JYFA 1DQ3A 3LL8A 4BHBA 1X47A 2ODRC 4GEQB 2EPNA 4MOYA 2ELZA 4DR3E 2HHHE 4WPYA 2EOZA 3EPJA 3UK3C 3ZTVA 4WSGA 2V89A 4MLVA 2N8XA 4I5NC 5KL7A 4NXNE 2JOBA 3DJWA 5TSEA 3HVQA 4X64E 4YHHE 2EOFA 2F8BA 1EH6A 2L33A 2JXPA 2YTFA 3KZYA 1X6EA 2WBUA 5LMUE 2R76A 4IJDA 2D9HA 4X8WA 2EN7A 2CT1A 4OR9A 4J6OA 4I8OA 2Z72A 2UXCE 3H64A 2EL5A 4R2QA 2MC6A 4KZSA 4R2AA 4KHPE 2EQ3A 2O8AA 1PJQA 2RPCA 2NUGA 2V88A 1I94E 2RS7A 1XMQE 4JI4E 1MF8A 3J81C 2LBSB 3V4YA 1ZAAC 1DGCA 4LF9E 2LRSA 3KWRA 3P71C 4R03A 4AQYE 4JYAE 2NYLC 2UUAE 3T1IA 2GPIA 2DLQA 2JOXA 2WDCA 1IBME 1Z2WA 2EMZA 3DW8C 1T4LB 1J5EE 1A1LA 4B3SE 4BC7A 5IWAE 2B3TB 3BIDA 4LFCE 1WHQA 1NEIA 2EMWA 3H09A 1T4OA 3N5UA 2LTSA 1SFEA 2GHFA 1P47A 4H1YP 2DMYA 1IMUA 2HY1A 1GZ6A 2MDGA 3FGAC 4GKKE 1XNRE 3OMLA 4YKEA 3RL5A 2EM9A 4N4RB 3THOB 2KKNA 1TCOA 2M9AA 4L5NC 2LT7A 3TQMA 3ECRA 2I13A 2K4VA 3H68A 1A1KA 1OIEA 4ZVZA 4LF5E 4DV3E 4GKJE
chains in the Genus database with same CATH topology

4H2IA 4UT3B 2BCDA 3QFKA 4Q7FA 4WWLA 4KBPA 4LTYA 4ZX2A 3AUZA 4FBQA 2HYOA 5IOHA 2YEQA 4FCXA 2DXLA 4FBWA 1JK7A 4TUGA 3PSOA 4V0XA 2Z06A 4O5GA 1UF3A 3TGHA 3H66A 1UTEA 1AUIA 2ZO9B 3IB7A 2IE4C 1II7A 4H2GA 1Z2XA 4MOVA 4DSYA 2CV9A 2Z1AA 4UT3A 4M0VA 2WDFA 4B2OA 5J28A 1QHWA 3JYFA 3LL8A 1HO5A 3FLOA 1V73A 3KBPA 4G9JA 4MOYA 3DSCA 1SU1A 1HPUA 2GJUA 4LU9A 3ZTVA 4XPNA 4HD0A 4I5NC 4O4KA 2BQ8X 4ORAA 2AHDA 1NNWA 3THNA 3HVQA 4DHLA 3H68A 4TUIA 2NYMC 3DSDA 1OIDA 4UT2A 1S3LA 3GVEA 4LACC 2O8GA 2QFRA 4FBKA 4OR9A 4NZVA 4J6OA 2Z72A 4IL1A 3H69A 3E7AA 1W24A 4MP0A 3H64A 4V0VA 3EGGA 2BDXA 5JPEA 2DXNA 2QFPA 2ZOAA 4I5LC 4F0ZA 5GTUA 5INBA 1WARA 2O8AA 5DNYA 4JA7A 2A22A 5JPFA 1G5BA 3QG5C 1S95A 1MF8A 4O24A 3C5WC 3E0JA 1M63A 3V4YA 3ZU0A 5EQVA 1FJMA 3QFMA 3CK2A 4KKZA 3RL4A 4O43A 2DFJA 3P71C 3IB8A 2IAEC 2NYLC 5B8IA 3T1IA 3RQZA 4H2BA 2XMOA 5JJTA 2WDCA 1Z2WA 2YVTA 1QFCA 2QJCA 3DW8C 3H67A 3H63A 1U32A 3AV0A 3PSNA 1WAO1 2JOGA 4H2FA 2R17A 1S3NA 4JA9A 1S8EA 2NXFA 1XM7A 4DT2A 3E7BA 4IYPC 3D03A 3C9FA 3N5UA 4ORBA 2IE3C 2USHA 5C1VA 3IVDA 2WDEA 1T70A 3K7WC 4H1YP 1KBPA 2HY1A 2ZBMA 4ORCA 2P6BA 3FGAC 3IVEA 3QFOA 4H1SA 3H62B 4YKEA 3RL5A 4UWQA 5HPEA 3H61A 1IT6A 3THOB 2KKNA 1TCOA 3RL3A 5F3WA 2NPPC 1T71A 1USHA 3EGHA 1OI8A 1HP1A 2Q8UA 3QFNA 1S70A 3H60A 2HYPA 4V0WA 1OIEA 4ZVZA 2WDDA 3ICFA 1XZWA 1S3MA 3K7VC
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4H2I A;  4UT3 B;  2BCD A;  3QFK A;  4Q7F A;  4WWL A;  4KBP A;  4LTY A;  4ZX2 A;  3AUZ A;  4FBQ A;  2HYO A;  5IOH A;  4FCX A;  4FBW A;  1JK7 A;  4TUG A;  3PSO A;  4V0X A;  2Z06 A;  4O5G A;  1UF3 A;  3TGH A;  3H66 A;  1UTE A;  1AUI A;  3IB7 A;  2IE4 C;  1II7 A;  4H2G A;  1Z2X A;  4MOV A;  4DSY A;  2CV9 A;  2Z1A A;  4UT3 A;  4M0V A;  2WDF A;  4B2O A;  5J28 A;  1QHW A;  3JYF A;  3LL8 A;  1HO5 A;  1V73 A;  3KBP A;  4G9J A;  4MOY A;  3DSC A;  1SU1 A;  1HPU A;  2GJU A;  4LU9 A;  3ZTV A;  4XPN A;  4HD0 A;  4I5N C;  4O4K A;  2BQ8 X;  4ORA A;  2AHD A;  1NNW A;  3THN A;  3HVQ A;  4DHL A;  3H68 A;  4TUI A;  2NYM C;  1OID A;  3DSD A;  4UT2 A;  1S3L A;  3GVE A;  4LAC C;  2O8G A;  2QFR A;  4FBK A;  4OR9 A;  4NZV A;  4J6O A;  2Z72 A;  4IL1 A;  3H69 A;  3E7A A;  1W24 A;  4MP0 A;  3H64 A;  4V0V A;  3EGG A;  2BDX A;  5JPE A;  2QFP A;  4I5L C;  4F0Z A;  5INB A;  5GTU A;  1WAR A;  2O8A A;  5DNY A;  4JA7 A;  2A22 A;  5JPF A;  1G5B A;  3QG5 C;  1S95 A;  1MF8 A;  4O24 A;  3C5W C;  3V4Y A;  1M63 A;  3ZU0 A;  5EQV A;  1FJM A;  3QFM A;  3CK2 A;  4KKZ A;  3RL4 A;  4O43 A;  2DFJ A;  3P71 C;  3IB8 A;  2IAE C;  2NYL C;  5B8I A;  3T1I A;  3RQZ A;  4H2B A;  2XMO A;  5JJT A;  2WDC A;  1Z2W A;  2YVT A;  1QFC A;  2QJC A;  3DW8 C;  3H67 A;  3H63 A;  1U32 A;  3AV0 A;  3PSN A;  1WAO 1;  2JOG A;  4H2F A;  2R17 A;  1S3N A;  4JA9 A;  1S8E A;  2NXF A;  1XM7 A;  4DT2 A;  3E7B A;  4IYP C;  3N5U A;  3C9F A;  4ORB A;  2IE3 C;  2USH A;  5C1V A;  3IVD A;  2WDE A;  1T70 A;  3K7W C;  4H1Y P;  1KBP A;  2HY1 A;  2ZBM A;  4ORC A;  2P6B A;  3FGA C;  3IVE A;  3QFO A;  4H1S A;  3H62 B;  4YKE A;  3RL5 A;  4UWQ A;  5HPE A;  3H61 A;  1IT6 A;  3THO B;  2KKN A;  1TCO A;  3RL3 A;  5F3W A;  2NPP C;  1T71 A;  1USH A;  3EGH A;  1OI8 A;  1HP1 A;  2Q8U A;  3QFN A;  1S70 A;  3H60 A;  2HYP A;  4V0W A;  1OIE A;  4ZVZ A;  2WDD A;  3ICF A;  1XZW A;  1S3M A;  3K7V C; 
#chains in the Genus database with same CATH topology
 2YWQ A;  5LLQ A;  2BCD A;  4L8N A;  5IT9 C;  4Q7F A;  4JI8 E;  1IBL E;  2EOQ A;  2EMY A;  4ZX2 A;  3J80 C;  3AUZ A;  3HXL A;  2HYO A;  2KOU A;  4V0X A;  4M9V C;  3H66 A;  1AUI A;  4BC9 A;  2DB2 A;  2LUP B;  1RMD A;  3JU0 A;  1HNZ E;  4H2G A;  2K7I A;  4DUY E;  4MOV A;  2J7J A;  2YRK A;  3IWC A;  5KL6 A;  4B2O A;  5J28 A;  4HTG A;  1QHW A;  1HO5 A;  1V73 A;  2DMI A;  4DV7 E;  3KBP A;  4G9J A;  3C4T A;  5AC5 A;  4JI6 E;  1HPU A;  3C4B A;  4LU9 A;  3C6K A;  2DLK A;  2ENH A;  4F6M A;  5AE2 A;  4O4K A;  1F2I G;  4HD0 A;  2AHD A;  3VYX A;  2FTX B;  1NNW A;  3K6Q A;  3LLH A;  3VYY A;  3F6H A;  2KHX A;  4UT2 A;  2EN2 A;  1S3L A;  3GVE A;  5A6K A;  2O8G A;  2EN1 A;  4NXM E;  2QFR A;  4FBK A;  5A2Q C;  1EH7 A;  4IL1 A;  3E7A A;  2CSH A;  2YSO A;  2EM2 A;  2YTN A;  4M30 A;  3EGG A;  4ZYD A;  2F4V E;  3ADL A;  2EML A;  2JWO A;  2WCC 3;  4F0Z A;  4I5L C;  5DNY A;  3RMP A;  5JPF A;  1YYO A;  2EOI A;  5KL3 A;  4O24 A;  2EPL X;  2YTD A;  5EQV A;  2UXB E;  1ZBT A;  2DFJ A;  1JK2 A;  4GZN C;  2LO3 A;  3MHH C;  2IAE C;  5B8I A;  4KWY A;  2L3J A;  3HQ1 A;  2JVA A;  5JJT A;  4RH8 A;  2EMX A;  4DV5 E;  2ADR A;  2YVT A;  4JI7 E;  3T1H E;  2EPR A;  4M2Z A;  1QFC A;  3H67 A;  1EKZ A;  1X3C A;  1KYQ A;  1U32 A;  3PSN A;  4WX9 A;  1S8E A;  2LTR A;  2LMZ A;  5IXM B;  2PRT A;  4DT2 A;  2EOJ A;  1HR0 E;  2EQ0 A;  4ORB A;  1A1G A;  1STU A;  2B9D A;  4BCA A;  2IE3 C;  4ZYG A;  3IVD A;  2M7Q A;  2ELY A;  1YPN A;  2EN3 A;  2EOX A;  4F9A B;  3P1X A;  2EMH A;  4ORC A;  5KL4 A;  2LVH A;  3IVE A;  3QFO A;  3HPZ A;  4YY3 E;  1DI2 A;  2YRM A;  1MEY C;  5HPE A;  4LFB E;  1HNW E;  2YU5 A;  5F3W A;  2VF1 A;  2EPZ A;  2NPP C;  3ZOQ B;  4R2D A;  3EGH A;  2BB8 A;  2EMF A;  1OI8 A;  2EN8 A;  4DKK A;  4V0W A;  5A6B D;  4P78 A;  4DR2 E;  2A25 A;  4B3T E;  4R2E A;  1XZW A;  4JI1 E;  1FJG E;  2EPK X;  2EPU A;  2FGG A;  3MHS C;  4WWL A;  4F9C B;  2NA2 A;  5FLX C;  1WJP A;  2BBG A;  5IOH A;  5IV8 B;  2RS6 A;  4TUG A;  1BBG A;  1B69 A;  2EL4 A;  3BGH A;  4NHR A;  3PSO A;  2Z06 A;  4O5G A;  2L3C A;  2YTO A;  2ZO9 B;  3IB7 A;  2EM3 A;  2EM6 A;  2L8T A;  3HTX A;  2IE4 C;  2KON A;  1II7 A;  1Z2X A;  2CV9 A;  2Z1A A;  1BBO A;  4JI2 E;  1AAY A;  2JPA A;  4F2J C;  3DSC A;  4R2S A;  2UXD E;  1SU1 A;  2EOR A;  2EE8 A;  2IHR 1;  4HEI A;  4Q35 B;  2EM7 A;  1TN9 A;  4XPN A;  2L2K B;  2EOM A;  2DSY A;  5T6J A;  4B3R E;  4ORA A;  3THN A;  1PKP A;  2EPO A;  2RQL A;  4DHL A;  2YTJ A;  4LF8 E;  4DV6 E;  2NYM C;  3ADJ A;  2UUB E;  4OX9 E;  2ENA A;  1A1H A;  1LLM C;  2MKN A;  4JV5 E;  1GTK A;  2JY9 A;  2LV2 A;  4NZV A;  1TF3 A;  2V86 A;  4F9B B;  2EQ1 A;  3H69 A;  4MP0 A;  2VQE E;  5A6A A;  2BDX A;  5JPE A;  2DXN A;  1YUI A;  4BS9 A;  2QFP A;  1WAR A;  1Z1B A;  1A1I A;  2A22 A;  1G5B A;  4DV2 E;  4BHC A;  4BBY A;  1S95 A;  2L2M A;  2RTX A;  2EPM X;  3C5W C;  1M63 A;  2L6M A;  3JTZ A;  4WXD A;  2EPX A;  3CK2 A;  3RL4 A;  4O43 A;  3HPS A;  2EOS A;  1L4S A;  1YSA C;  2L2N A;  4LF6 E;  2E1M A;  5LMN E;  3RQZ A;  4H2B A;  4P7D A;  2I9I A;  4K0K E;  2YZT A;  1X49 A;  2DGC A;  1YZ9 A;  2QJC A;  3MSW A;  3H63 A;  3JAM C;  3AV0 A;  4B3M E;  1ZU1 A;  4H2F A;  1BB8 A;  4WFT A;  1S3N A;  4JA9 A;  4DR1 E;  5BR8 E;  1PDA A;  1HNX E;  3BF2 A;  3KZZ A;  3EPH A;  4IYP C;  2M1S A;  3C9F A;  3LML A;  2USH A;  5C1V A;  2JR1 A;  1T70 A;  5ADZ A;  3K7W C;  2WBT A;  2YU8 A;  1KBP A;  3EPK A;  2ODR D;  2YRH A;  1YYW A;  2EOH A;  4LF7 E;  3H62 B;  4R2C A;  4UWQ A;  2EPA A;  3H61 A;  5LL6 R;  1IT6 A;  2N3H A;  2DRP A;  2RSM A;  2EM8 A;  5KL2 A;  1G2D C;  1USH A;  1AH5 A;  2E72 A;  4DR5 E;  1X48 A;  2Q8U A;  2DIX A;  1S70 A;  4DUZ E;  3H60 A;  2HYP A;  3VK6 A;  2EMB A;  2NAB A;  1N34 E;  2WDD A;  1S3M A;  3K7V C;  2NUF A;  1T4N A;  4DR4 E;  1FKA E;  2R1F A;  2L92 A;  2VE7 C;  4LTY A;  4DMI A;  2EOE A;  4KBP A;  2EL6 A;  4X65 E;  2YEQ A;  2DXL A;  1ZBQ A;  2EN6 A;  1JK7 A;  1N3G A;  2LCE A;  3TGH A;  2EOY A;  1EH8 A;  1UBD C;  1UTE A;  1IBK E;  2EM5 A;  4BMJ A;  4X9J A;  4F6N A;  2E5L E;  1N33 E;  1J26 A;  5A6J A;  2EPP A;  3L00 A;  2EMA A;  2EM4 A;  4UT3 A;  1UN6 B;  2EJ4 A;  4DSY A;  2LE2 A;  2EN4 A;  4R2R A;  2UU9 E;  2JYA A;  2MKD A;  5AE1 A;  3EPL A;  3ADG A;  1WHN A;  3FLO A;  4OOG C;  4JI3 E;  1IQS A;  2EPC A;  1YFH A;  2GJU A;  1WRJ A;  4DV1 E;  2YTG A;  1N36 E;  4MLQ A;  1PJS A;  4F54 A;  5AE3 A;  2YT4 A;  2BQ8 X;  2N3G A;  2YTQ A;  2HC5 A;  4TUI A;  1OID A;  3DSD A;  2EZ6 A;  1RQ0 A;  4LAC C;  4DV4 E;  2UUC E;  1XNQ E;  4WXC A;  2V83 A;  5A6B A;  2RSI A;  1G2F C;  3J7A G;  1SR9 A;  5KL5 A;  1W24 A;  1X5W A;  2V85 A;  2YTP A;  1WXR A;  4V0V A;  2M4I A;  1XMO E;  1GQE A;  1NCS A;  3F6G A;  2YTE A;  2NUE A;  4ZYE A;  2ZOA A;  5INB A;  5GTU A;  4JA7 A;  1TF6 A;  1X6F A;  4WYQ B;  2V8Q B;  4DR6 E;  3QG5 C;  3OTO E;  2ZM6 E;  3T1Y E;  3E0J A;  3ZU0 A;  1RC7 A;  3VHT B;  1UIL A;  2HGH A;  1KJK A;  1FJM A;  2LJU A;  3QFM A;  4KKZ A;  2VRD A;  3IB8 A;  2B7T A;  3IWD A;  2EMK A;  2H36 X;  4X62 E;  2XMO A;  4JI0 E;  2YSP A;  2LJH A;  2MDR A;  2YTI A;  2CPN A;  2VQF E;  1A1F A;  1WAO 1;  2JOG A;  2R17 A;  1UHZ A;  4R2P A;  4IS1 C;  4Q28 A;  1T38 A;  1XM7 A;  2NXF A;  1JK1 A;  4DR7 E;  1YUJ A;  3E7B A;  3D03 A;  2EOO A;  1YYK A;  2WDE A;  2JP9 A;  1X6H A;  4FK5 C;  4WSP A;  4R8O A;  2EMC A;  2ZBM A;  2EMG A;  2P6B A;  4H1S A;  2HJJ A;  1A1J A;  2EWL A;  1PJT A;  3DF6 A;  2YPN A;  1N32 E;  2EM0 A;  1T39 A;  3RL3 A;  2GLI A;  1QNT A;  3IWB A;  3M99 B;  1T71 A;  2ENC A;  2WBS A;  5CFF E;  1HP1 A;  2G7H A;  3QFN A;  2CTD A;  4RHB B;  4X66 E;  3BBG A;  3J7Y p;  4J8Z A;  3EQ1 A;  2FV4 B;  3ICF A;  4H2I A;  4UT3 B;  2V87 A;  4DV0 E;  3QFK A;  4ZYH A;  1IQO A;  5AAS A;  4FBQ A;  1QU6 A;  1ZR9 A;  2LUQ A;  3FIG A;  4FCX A;  5A69 A;  2EP3 A;  4FBW A;  1MGT A;  3ADI A;  1UF3 A;  2EMI A;  1O0W A;  2MC5 A;  3C6M A;  5AC4 A;  2WZO A;  4LF4 E;  2B7V A;  4M0V A;  4LFA E;  2WDF A;  4JI5 E;  3JYF A;  1DQ3 A;  3LL8 A;  4BHB A;  1X47 A;  2ODR C;  4GEQ B;  2EPN A;  4MOY A;  2ELZ A;  4DR3 E;  2HHH E;  4WPY A;  2EOZ A;  3EPJ A;  3UK3 C;  3ZTV A;  4WSG A;  2V89 A;  4MLV A;  2N8X A;  4I5N C;  5KL7 A;  4NXN E;  2JOB A;  3DJW A;  5TSE A;  3HVQ A;  4X64 E;  4YHH E;  2EOF A;  2F8B A;  1EH6 A;  2L33 A;  2JXP A;  2YTF A;  3KZY A;  1X6E A;  2WBU A;  5LMU E;  2R76 A;  4IJD A;  2D9H A;  4X8W A;  2EN7 A;  2CT1 A;  4OR9 A;  4J6O A;  4I8O A;  2Z72 A;  2UXC E;  3H64 A;  2EL5 A;  4R2Q A;  2MC6 A;  4KZS A;  4R2A A;  4KHP E;  2EQ3 A;  2O8A A;  1PJQ A;  2RPC A;  2NUG A;  2V88 A;  1I94 E;  2RS7 A;  1XMQ E;  4JI4 E;  1MF8 A;  3J81 C;  2LBS B;  3V4Y A;  1ZAA C;  1DGC A;  4LF9 E;  2LRS A;  3KWR A;  3P71 C;  4R03 A;  4AQY E;  4JYA E;  2NYL C;  2UUA E;  3T1I A;  2GPI A;  2DLQ A;  2JOX A;  2WDC A;  1IBM E;  1Z2W A;  2EMZ A;  3DW8 C;  1T4L B;  1J5E E;  1A1L A;  4B3S E;  4BC7 A;  5IWA E;  2B3T B;  3BID A;  4LFC E;  1WHQ A;  1NEI A;  2EMW A;  3H09 A;  1T4O A;  3N5U A;  2LTS A;  1SFE A;  2GHF A;  1P47 A;  4H1Y P;  2DMY A;  1IMU A;  2HY1 A;  1GZ6 A;  2MDG A;  3FGA C;  4GKK E;  1XNR E;  3OML A;  4YKE A;  3RL5 A;  2EM9 A;  4N4R B;  3THO B;  2KKN A;  1TCO A;  2M9A A;  4L5N C;  2LT7 A;  3TQM A;  3ECR A;  2I13 A;  2K4V A;  3H68 A;  1A1K A;  1OIE A;  4ZVZ A;  4LF5 E;  4DV3 E;  4GKJ E; 
#chains in the Genus database with same CATH homology
 4H2I A;  4UT3 B;  2BCD A;  3QFK A;  4Q7F A;  4WWL A;  4KBP A;  4LTY A;  4ZX2 A;  3AUZ A;  4FBQ A;  2HYO A;  5IOH A;  2YEQ A;  4FCX A;  2DXL A;  4FBW A;  1JK7 A;  4TUG A;  3PSO A;  4V0X A;  2Z06 A;  4O5G A;  1UF3 A;  3TGH A;  3H66 A;  1UTE A;  1AUI A;  2ZO9 B;  3IB7 A;  2IE4 C;  1II7 A;  4H2G A;  1Z2X A;  4MOV A;  4DSY A;  2CV9 A;  2Z1A A;  4UT3 A;  4M0V A;  2WDF A;  4B2O A;  5J28 A;  1QHW A;  3JYF A;  3LL8 A;  1HO5 A;  3FLO A;  1V73 A;  3KBP A;  4G9J A;  4MOY A;  3DSC A;  1SU1 A;  1HPU A;  2GJU A;  4LU9 A;  3ZTV A;  4XPN A;  4HD0 A;  4I5N C;  4O4K A;  2BQ8 X;  4ORA A;  2AHD A;  1NNW A;  3THN A;  3HVQ A;  4DHL A;  3H68 A;  4TUI A;  2NYM C;  3DSD A;  1OID A;  4UT2 A;  1S3L A;  3GVE A;  4LAC C;  2O8G A;  2QFR A;  4FBK A;  4OR9 A;  4NZV A;  4J6O A;  2Z72 A;  4IL1 A;  3H69 A;  3E7A A;  1W24 A;  4MP0 A;  3H64 A;  4V0V A;  3EGG A;  2BDX A;  5JPE A;  2DXN A;  2QFP A;  2ZOA A;  4I5L C;  4F0Z A;  5GTU A;  5INB A;  1WAR A;  2O8A A;  5DNY A;  4JA7 A;  2A22 A;  5JPF A;  1G5B A;  3QG5 C;  1S95 A;  1MF8 A;  4O24 A;  3C5W C;  3E0J A;  1M63 A;  3V4Y A;  3ZU0 A;  5EQV A;  1FJM A;  3QFM A;  3CK2 A;  4KKZ A;  3RL4 A;  4O43 A;  2DFJ A;  3P71 C;  3IB8 A;  2IAE C;  2NYL C;  5B8I A;  3T1I A;  3RQZ A;  4H2B A;  2XMO A;  5JJT A;  2WDC A;  1Z2W A;  2YVT A;  1QFC A;  2QJC A;  3DW8 C;  3H67 A;  3H63 A;  1U32 A;  3AV0 A;  3PSN A;  1WAO 1;  2JOG A;  4H2F A;  2R17 A;  1S3N A;  4JA9 A;  1S8E A;  2NXF A;  1XM7 A;  4DT2 A;  3E7B A;  4IYP C;  3D03 A;  3C9F A;  3N5U A;  4ORB A;  2IE3 C;  2USH A;  5C1V A;  3IVD A;  2WDE A;  1T70 A;  3K7W C;  4H1Y P;  1KBP A;  2HY1 A;  2ZBM A;  4ORC A;  2P6B A;  3FGA C;  3IVE A;  3QFO A;  4H1S A;  3H62 B;  4YKE A;  3RL5 A;  4UWQ A;  5HPE A;  3H61 A;  1IT6 A;  3THO B;  2KKN A;  1TCO A;  3RL3 A;  5F3W A;  2NPP C;  1T71 A;  1USH A;  3EGH A;  1OI8 A;  1HP1 A;  2Q8U A;  3QFN A;  1S70 A;  3H60 A;  2HYP A;  4V0W A;  1OIE A;  4ZVZ A;  2WDD A;  3ICF A;  1XZW A;  1S3M A;  3K7V C;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

4O43A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations