4BPMA

Crystal structure of a human integral membrane enzyme
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
162
structure length
162
Chain Sequence
SPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHFLPAALRAALLGRLRTLRPW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy.
pubmed doi rcsb
molecule tags Isomerase
source organism Homo sapiens
molecule keywords PROSTAGLANDIN E SYNTHASE, FUSION PEPTIDE
total genus 66
structure length 162
sequence length 162
ec nomenclature ec 4.4.1.20: Leukotriene-C(4) synthase.
pdb deposition date 2013-05-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01124 MAPEG MAPEG family
A PF01124 MAPEG MAPEG family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.550 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Membrane associated eicosanoid/glutathione metabolism-like domain 4bpmA00
3HKKA 5K0IA 5HV9A 4BPMA 4AL0A 4AL1A 4JCZA 4YL3A 4NTBA 2UUHA 5BQIA 4YK5A 4JC7A 5BQHA 2UUIA 4JRZA 3PCVA 4YL0A 3B29A 4NTAA 2PNOA 5BQGA 4WABA 2Q7RA 4YL1A 4J7TA 3LEOA 2H8AA 4NTFA 3DWWA 4J7YA
chains in the Genus database with same CATH superfamily
4MTFA 4YWQA 3LUTB 1C02A 2KGOA 2YL3A 256BA 1BDJB 1QZXA 4WGYA 3T6JA 3PMRA 3G50A 4U5CE 3TQOA 3U8VA 1L7CA 1OR3A 3CZ6A 4CDVA 3KYJA 1LI7A 2Q3TA 3FAJA 3AQCA 3MLGA 3K1IC 4JC7A 5COMA 4IRUA 3UR3C 1C17M 2YEVA 2RSEB 3PCVA 3FXHA 4MTGA 1ZHTA 4LERA 3G4ZA 4CSAA 3PDMP 4G7ZF 1ZU4A 2L9JA 5D92A 2PX0A 4AE4B 4XLNF 3TK0A 2NUTB 2KK1A 5A6BD 4PJLA 1QPUA 5B1BC 3SYNA 3IHUA 4NTFA 4CDAA 1NSGB 3EH1A 5KYYB 3C18A 3EFOB 3KPHA 1ORJA 4CDYA 4PR9A 2TMVP 1E85A 2G62A 3SP1A 4XPXA 3ZQYA 1D0YA 1Q0MA 1O3UA 3QTHA 1B68A 1Q0DA 1ZHZA 4YK5A 4XEVA 1CGOA 2IBFA 2Y3BA 2R25A 2YKZA 3Q6NA 3U9MA 4CS9A 4FAPB 2C03A 2VCAA 2XSEA 3JT1A 4BJ6C 1SYQA 2O9XA 2X51A 2E87A 5BQGA 3U2MA 1A7DA 1FNTc 4MTOA 2Q7RA 1ZZPA 5DVWA 1TWCA 2XM0A 4E7ZA 4LLCA 3DAGA 2ZPAA 3AG1C 3M15A 3KL4A 4P9FA 4PJNA 4U9EA 4XEKA 4D4NA 1NU9C 4MW8A 2HMZA 3WODF 3S0XA 2FGYA 5KYUA 2V26A 1LKXA 3NMKA 4C7OB 4U5HA 3JCUQ 1GQAA 2EIMC 2M64A 2M4EA 3FOPA 4JCZA 4JIOA 4MVRA 4K0DA 1I5NA 3C8ZA 4RBNA 2YRFA 2W4BA 3ZG1A 3M1CB 4QDLA 1M57C 3X1OA 2OCCC 2LP4A 2UUIA 3ZDLA 4W8PA 2DYRC 4HEAJ 1RKEA 3SXZA 4YT4A 5KYXA 4H4KC 2J7PD 1VTMP 1G8XA 2LQGA 2XS8A 3RQEA 2IXOA 3AG4C 2B0JA 3IQCA 4NQFA 3U9JA 5L3QA 3K66A 5DS5A 2L81A 4OD4A 4EBJA 1ZYRF 1Z6AA 2DB4A 3HNJA 3LEOA 3C8GD 1T6UA 1T9KA 4BEJA 1IZMA 1U6HA 5GPGB 1J8YF 2QTVA 1Q0KA 4OIRF 4CS9C 3EGXB 3H2VA 1I4YA 1WASA 5L0JA 2PFDA 1K40A 1OCOC 2YLGA 1TFKB 2Q4FA 3QMKA 4JJGA 5JP7A 3U3FA 3U8PA 4EUKB 3DXJF 3LAYA 3C8GB 1NZEA 3B0VC 5EHHA 3L0IA 2LFDA 3GORA 3M4CA 3S29A 4DXWA 2QNLA 3GEIA 2EPLX 2ZXPA 1FMWA 5AC5A 2IM8A 4NTAA 3EPVA 3DAFA 3LNRA 4M63A 3NYMA 3L8IA 3U2LA 2OEXA 3I5PA 5JSLA 1MQVA 3GODA 4N06A 3S9OA 1JPNA 1JOGA 3K1IA 2H8AA 1RJ9A 3N2ZB 3US6A 5FZTA 3FAPB 2Y39A 3O55A 4J7YA 1NFOA 1TR2A 1HE1A 3DZAA 3LJBA 2R02A 4E0IA 3SEOA 3TJ5A 3ECSA 2FFHA 2G3KA 4PFOA 5B3SC 5HV9A 2XXAA 4JEBA 3NMJA 5A69A 4U9DA 3FHDA 4JJFA 3NYJA 4DRIB 3UNGC 5DS6A 2ZXRA 4JE9A 3VYWA 1R4TA 1LM3B 2KC3A 2BC5A 4PJJA 3TD7A 3V5XA 2NSGA 2EPOA 3EGDB 4JTCB 1LE4A 3LESA 5BUOA 3EH2A 2KQ9A 2GAQA 2WL8A 1LVKA 3J06A 2ETSA 1ZHWA 5IY5C 4B6IA 4DVZA 1QSPA 4UDVA 1TWHA 4YL1A 3RF3A 2EILC 2WB7A 3ZSUA 5JS5A 1HMOA 1V4AA 1D0XA 2R9RB 2R7RA 4J32B 1Z7Qc 4QI0A 1FFTC 1OXBA 4LDQA 4IWBA 4BJ6A 4EKWA 4Q5SF 5T3TA 4MVMA 2LSEA 2HZ8A 3MYIA 1O87A 3MX3A 3A9CA 4IB4A 4U5EE 2Q9CA 4I44A 3WHNA 2KJGA 2MYSA 2RD9A 5KYWA 2YL0A 3W4YA 1M2VA 1G4WR 3FDQA 2J9WA 4ER9A 4OIPF 3KYIA 2GWWA 4QI2A 2HS5A 2J9VA 2LCHA 3DJUB 1VYKA 4L6RA 1AEPA 3NYLA 4XTKA 2H7OA 5HSWA 3VRCA 2LD6A 4JRZA 2XXAB 3T4RA 2YLDA 5L0GA 1Q0GA 1HW1A 1YAUO 3F47A 2GFHA 2YL7A 1IW7F 1QQ3A 2JD3A 2W4MA 1BR1A 2EPKX 2XS1A 3E9VA 4JTAB 2IYLD 2NSFA 5DQTA 2BE5F 1E86A 2HKVA 2DI3A 2VCCA 3UGPA 4YT2A 4XLPF 1R5ID 4MVZA 1JMWA 4EWCA 3WG7C 1ZW2A 2H7BA 4FESA 4U5BE 5A6JA 3L34A 4J30B 4NCQA 2A0BA 4PK4A 3UMKA 3NDBB 2IXMA 3ABMC 4KNVA 5K0IA 1TWGA 2Y3DA 4MQ9F 3S28A 4Z9HA 2C04A 2OEVA 2Q9AA 1JAFA 3QW1A 4YJWA 3K6BA 4DBRA 2R7QA 4KBLA 4ULWA 3W2VA 4HFFB 4O6MA 1A0BA 1O5HA 2A6HF 2G3VA 2ZD9A 3HLZA 4ZLCA 1WTYA 3ASOC 1LS1A 1YDIA 1YVIA 1FAPB 1CGNA 2VCBA 3CQZA 4P9TA 2YQYA 5E3AA 4JW1A 3AGTA 3L1MA 3OWTA 5DS4A 3JSEO 4FX5A 4CJGA 5COFA 2NUPA 3ZVRA 4LLEA 1HW2A 2KW3C 3ASNC 2A68F 5L3VA 4J7TA 3FVYA 3HTKC 4K1OA 5JRAA 2R05A 1MMDA 1W2WA 3V5ZA 1HY5A 3SXKA 5B3IA 3ATPA 2HJMA 2EIJC 2JPUA 1OCRC 2J9UA 4X0RA 3TULA 5F5FA 4I1OB 5JVEA 3KH2A 1OKKA 4BPMA 3RH3A 1LI5A 1QKRA 2HFIA 1EQ1A 3N0TA 4KC9A 3O39A 3O10A 2W9YA 4MVQA 2R7XA 2J45A 4U5FE 5KYUB 2HMQA 2PP4A 2QLAA 1QVXA 3RFYA 3RVZA 4OIQF 3M79A 2YWAA 3LS1A 4MVSA 3B0PA 2P0NA 5E2QA 2CYDA 2R7OA 3EG9A 5JLIA 5FCLA 2R7WA 3U3BA 3E70C 1DOWA 4CS8A 1FMVA 1RKEB 4RDAA 5KYXB 3ZQVA 4U5GA 3L8JA 3ABKC 4D4XA 3C7JA 2DGJA 1I4ZA 5B1AC 1C03A 2CNWD 3A11A 1JPJA 4FWVA 5CIVA 2AWCA 3KMIA 3LEVA 4P6IC 2HSQA 3C63A 1VB5A 1YYXA 2WZFA 4JURI 3IPMO 4MNDA 3NRHA 5L0IA 1OW8A 2VB6A 4Q7CA 1K04A 1MNEA 1Z5ZA 3POVA 3KKBA 4O6NA 3DE8A 4GEHA 4PJMA 4YT8A 1OCCC 3R7CA 1T5OA 1V74B 3I5QA 2JX0A 3VM6A 2J7PA 2PNOA 1G5ZA 3T9OA 3JTLO 4JVSA 2R7TA 2HUJA 2XLOA 1KTMA 1ZHXA 2J8WA 3GWNA 5TJ5E 2J9BA 2HJ3A 1ZVZA 3GM1A 5JT4A 3JRMO 2GA0A 2H7VC 4E0HA 5F5HA 2Y3GA 1CPRA 4RD9A 3X2QC 4OIOF 3IQ5A 3NG1A 2WZLA 4O7GA 1MMGA 1MMAA 1D0ZA 1AVOB 2WZGA 1HMDA 1Y4CA 2EINC 2XL8A 3DM9B 3RKOF 2OOCA 2ZXWC 4NC3A 5L0HA 1ST6A 1FR0A 4AL1A 1RJ9B 3N24A 2AVKA 4CS8C 4DRJB 2XRHA 1T01A 4OD5A 3EQLF 5D91A 4MW3A 2MWQA 4E17A 3JYYA 1H7IA 2XLWA 2HSBA 4N6CA 4R32A 4XEFA 1Z23A 2ASRA 3LS0A 3EJNA 3HJCA 3QW0A 3K33A 1UG7A 4YN0B 2IXPA 4A4AA 4CS7A 1F1MA 3B29A 4YL0A 4CX9A 3TJ6A 3AQBA 1T6IA 2XL6A 4O6YA 1APCA 4G7OF 4LDRA 3DI5A 3DM5A 4DJ9A 1G4US 3CAXA 4AX2A 4F4BA 2PX3A 4NY3A 5CI9A 2OJQA 1BBHA 4AK9A 4BEMJ 4EHPA 3UGOA 1WOLA 1KNYA 4YT5A 3RVYA 1GM5A 1VK5A 2KNHA 3DE9A 4E18A 3GM2A 2XLVA 4I1MA 1PV3A 1DOVA 1ZHYA 3RQGA 4NTBA 1OW7A 1CGME 2QUPA 2VASA 2KYHA 3AJMA 3FOOA 1PD1A 1NFNA 1S05A 2XL4A 3EZIA 4XQ1A 4XWJA 5T1DB 3VF0A 5KYWB 2YVKA 1M2VB 1U89A 1SF8A 3NKDA 2J46A 4DOZA 3C62A 4JTDB 4MS2A 3TOMA 1OXKA 3OA1A 2BL2A 4Z9JA 2XLDA 3GEEA 4N4WA 3ZWIA 1VLTA 5L0FA 1VYIA 3RIPA 1TQGA 2W45A 1PD0A 2I15A 3Q7GA 3DWWA 4ANJA 2P1AA 3RW0A 5T3WA 3IEEA 4CIPA 4CBEA 1YLMA 1SZIA 3BRJA 2IXNA 3DJNB 3K7DA 3DD7A 1AUEA 1TKNA 2Y69C 1D1BA 4IAQA 1FTSA 1VLSA 3LLIA 2YL1A 2YLIA 2A0UA 2NPUA 1OR2A 1WN0A 1RCPA 4G78A 5BQHA 3MYFA 4AE4A 5KYNA 4IAOA 2LFFA 2NUTA 1WATA 1WWPA 2VC9A 4GQHA 4PFPA 3UMIA 2L7AA 1RMVA 3Q7LA 1ORYA 4WABA 4KNWA 5AC4A 3CSKA 3EHMA 2YZSA 1Z63A 5KYYA 1MNDA 2A69F 1NLXA 4LACB 4ZLDA 3U0CA 3EFOA 2J0WA 2OQMA 4JEAA 2OU6A 1E83A 1TFOB 4WGZA 4WJ0A 3T6GB 3V5YA 5A6BA 2WVNA 2WVQA 4E7SA 2NUPB 1OKKD 3GEHA 1YYJA 4CJOA 3IQTA 1BZ4A 2Q00A 3AG3C 3HNIA 1JRAA 1D1CA 1Y6DA 1YA9A 2Z15A 3GM3A 5F28E 3GANA 2PF4E 3SXYA 3BEHA 3W2WA 2A6EF 2V3CC 1FFHA 1LIHA 1A7EA 3NKEA 2ZXOA 2XLMA 3EHNA 3O6XA 2OG2A 2AU5A 1TWAA 4A2NB 2XM4A 1ZW3A 5DQZA 3QVZA 3DKAA 4BJ5C 3RYLA 1BR2A 4JZAA 3ZTZA 5EGYA 2GDCA 2I8BA 2A1DD 2LIGA 3UMHA 4Z9IA 5COGA 2IOQA 2LK4A 2B0HA 4U5DE 2PBEA 3IQ6A 4EBKA 5DLJA 4C7OA 1J8MF 2HV6A 3TOLA 3EG9B 3FMSA 2DYSC 1L3PA 4BG0A 3NMIA 1ZU5A 4H54A 1EI7A 2WVOA 3HNKA 3DMDA 3H2UA 4EBBA 3ITFA 4ULVA 1V55C 4CSAC 2KSFA 4XPWA 3JYHA 2CDQA 1NG1A 5E3CA 1VOMA 1XZQA 5BQIA 4XPYA 3S90A 3HNLA 4LDKA 3SXMA 4BJ5A 2R7SA 1H9GA 3B71A 3SNHA 2L6HA 3R2PA 4IGGA 2EIKC 4HE8D 4CIHA 5A6AA 4K7BA 2F22A 4MVUA 3U5SA 1NBBA 4G0HA 1YA7O 2D5RB 3G4XA 2AP3A 3M4BA 1XZPA 1YJGA 3AG2C 1LS4A 3JZ0A 3LNMB 3EGXA 1YZAA 2QE9A 3B0UX 1HE9A 2J0XA 2L6GA 3AGUA 3SZRA 1BR4A 4DBQA 1E2XA 3JRTA 1EKYA 4IJJA 1OCZC 1M2OA 4O79A 2FAPB 2L6FA 1T6QA 2XLHA 3K1HA 3B9QA 4KI2A 3C8GA 1YARO 3W8IA 1CPQA 3T6BA 1GGQA 2YHSA 4EIYA 3HKKA 3I4UA 2EPNA 4JKVA 1RKCA 4IARA 3PHF2 2CNWA 4AL0A 1V54C 2EPMX 1LE2A 1Q0FA 5JUAA 4YL3A 4BJTA 1SMYF 2D4UA 4ONSA 2UUHA 4Q4ZF 1QLEC 4I3MA 4C3BA 5EK0A 5L0DA 4DVYP 3V7OA 3OEOA 1ORSC 3WAQA 1E84A 3MBGA 2P7VA 1XWJA 3H65A 1NU7D 2Q9BA 1K05A 1UFBA 4DRHB 5CI8A 3VAYA 5L0CA 2QY9A 3ZIBA 1LPEA 3MFNA 1A41A 3QZCA 1D1AA 2P61A 3LLKA 4MVOA 2AWYA 1Z3IX 2VH3A 1H6GA 1JR8A 1EA8A 5E33A 3JSZA 1WGWA 4PACA 4GYTA 4C3DA 3EGDA 3Q6MA 2X0CA 1U0BB 1SR2A 3AOUA 1A7VA 3EZHA 3ZC4A 3ZTMA 2P6VA 4OINF 1VMAA 2CGEA 2ICWG 2R7UA 2OJED 1MMNA 2R7VA 5AGFA 4C3EA 2XLEA 1OQCA 2R03A 2CCYA 4JCHA 1H9TA 1RXQA 1YZCA 1GS9A 2Y3HA 3W8HA 4W8KA 3GWLA 1M56C 1M6TA 3S27A 3CEXA 4HFKB 1PCXA 1N1CA 3QVYA 4G7HF 2OKUA 3ABLC 2MHRA 3RQFA 1KU2A 2NG1A 2CW0F 5A6KA 3S84A 4N6HA 4BJ1A 2HV7A 1OW6A 3F46A 1S7ZA
chains in the Genus database with same CATH topology
3HKKA 5K0IA 5HV9A 4BPMA 4AL0A 4AL1A 4JCZA 4YL3A 4NTBA 2UUHA 5BQIA 4YK5A 4JC7A 5BQHA 2UUIA 4JRZA 3PCVA 4YL0A 3B29A 4NTAA 2PNOA 5BQGA 4WABA 2Q7RA 4YL1A 4J7TA 3LEOA 2H8AA 4NTFA 3DWWA 4J7YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HKK A;  5K0I A;  5HV9 A;  4BPM A;  4AL0 A;  4AL1 A;  4JCZ A;  4YL3 A;  4NTB A;  2UUH A;  5BQI A;  4YK5 A;  4JC7 A;  5BQH A;  2UUI A;  4JRZ A;  3PCV A;  4YL0 A;  3B29 A;  4NTA A;  2PNO A;  5BQG A;  4WAB A;  2Q7R A;  4YL1 A;  4J7T A;  3LEO A;  2H8A A;  4NTF A;  3DWW A;  4J7Y A; 
#chains in the Genus database with same CATH topology
 4MTF A;  4YWQ A;  3LUT B;  1C02 A;  2KGO A;  2YL3 A;  256B A;  1BDJ B;  1QZX A;  4WGY A;  3T6J A;  3PMR A;  3G50 A;  4U5C E;  3TQO A;  3U8V A;  1L7C A;  1OR3 A;  3CZ6 A;  4CDV A;  3KYJ A;  1LI7 A;  2Q3T A;  3FAJ A;  3AQC A;  3MLG A;  3K1I C;  4JC7 A;  5COM A;  4IRU A;  3UR3 C;  1C17 M;  2YEV A;  2RSE B;  3PCV A;  3FXH A;  4MTG A;  1ZHT A;  4LER A;  3G4Z A;  4CSA A;  3PDM P;  4G7Z F;  1ZU4 A;  2L9J A;  5D92 A;  2PX0 A;  4AE4 B;  4XLN F;  3TK0 A;  2NUT B;  2KK1 A;  5A6B D;  4PJL A;  1QPU A;  5B1B C;  3SYN A;  3IHU A;  4NTF A;  4CDA A;  1NSG B;  3EH1 A;  5KYY B;  3C18 A;  3EFO B;  3KPH A;  1ORJ A;  4CDY A;  4PR9 A;  2TMV P;  1E85 A;  2G62 A;  3SP1 A;  4XPX A;  3ZQY A;  1D0Y A;  1Q0M A;  1O3U A;  3QTH A;  1B68 A;  1Q0D A;  1ZHZ A;  4YK5 A;  4XEV A;  1CGO A;  2IBF A;  2Y3B A;  2R25 A;  2YKZ A;  3Q6N A;  3U9M A;  4CS9 A;  4FAP B;  2C03 A;  2VCA A;  2XSE A;  3JT1 A;  4BJ6 C;  1SYQ A;  2O9X A;  2X51 A;  2E87 A;  5BQG A;  3U2M A;  1A7D A;  1FNT c;  4MTO A;  2Q7R A;  1ZZP A;  5DVW A;  1TWC A;  2XM0 A;  4E7Z A;  4LLC A;  3DAG A;  2ZPA A;  3AG1 C;  3M15 A;  3KL4 A;  4P9F A;  4PJN A;  4U9E A;  4XEK A;  4D4N A;  1NU9 C;  4MW8 A;  2HMZ A;  3WOD F;  3S0X A;  2FGY A;  5KYU A;  2V26 A;  1LKX A;  3NMK A;  4C7O B;  4U5H A;  3JCU Q;  1GQA A;  2EIM C;  2M64 A;  2M4E A;  3FOP A;  4JCZ A;  4JIO A;  4MVR A;  4K0D A;  1I5N A;  3C8Z A;  4RBN A;  2YRF A;  2W4B A;  3ZG1 A;  3M1C B;  4QDL A;  1M57 C;  3X1O A;  2OCC C;  2LP4 A;  2UUI A;  3ZDL A;  4W8P A;  2DYR C;  4HEA J;  1RKE A;  3SXZ A;  4YT4 A;  5KYX A;  4H4K C;  2J7P D;  1VTM P;  1G8X A;  2LQG A;  2XS8 A;  3RQE A;  2IXO A;  3AG4 C;  2B0J A;  3IQC A;  4NQF A;  3U9J A;  5L3Q A;  3K66 A;  5DS5 A;  2L81 A;  4OD4 A;  4EBJ A;  1ZYR F;  1Z6A A;  2DB4 A;  3HNJ A;  3LEO A;  3C8G D;  1T6U A;  1T9K A;  4BEJ A;  1IZM A;  1U6H A;  5GPG B;  1J8Y F;  2QTV A;  1Q0K A;  4OIR F;  4CS9 C;  3EGX B;  3H2V A;  1I4Y A;  1WAS A;  5L0J A;  2PFD A;  1K40 A;  1OCO C;  2YLG A;  1TFK B;  2Q4F A;  3QMK A;  4JJG A;  5JP7 A;  3U3F A;  3U8P A;  4EUK B;  3DXJ F;  3LAY A;  3C8G B;  1NZE A;  3B0V C;  5EHH A;  3L0I A;  2LFD A;  3GOR A;  3M4C A;  3S29 A;  4DXW A;  2QNL A;  3GEI A;  2EPL X;  2ZXP A;  1FMW A;  5AC5 A;  2IM8 A;  4NTA A;  3EPV A;  3DAF A;  3LNR A;  4M63 A;  3NYM A;  3L8I A;  3U2L A;  2OEX A;  3I5P A;  5JSL A;  1MQV A;  3GOD A;  4N06 A;  3S9O A;  1JPN A;  1JOG A;  3K1I A;  2H8A A;  1RJ9 A;  3N2Z B;  3US6 A;  5FZT A;  3FAP B;  2Y39 A;  3O55 A;  4J7Y A;  1NFO A;  1TR2 A;  1HE1 A;  3DZA A;  3LJB A;  2R02 A;  4E0I A;  3SEO A;  3TJ5 A;  3ECS A;  2FFH A;  2G3K A;  4PFO A;  5B3S C;  5HV9 A;  2XXA A;  4JEB A;  3NMJ A;  5A69 A;  4U9D A;  3FHD A;  4JJF A;  3NYJ A;  4DRI B;  3UNG C;  5DS6 A;  2ZXR A;  4JE9 A;  3VYW A;  1R4T A;  1LM3 B;  2KC3 A;  2BC5 A;  4PJJ A;  3TD7 A;  3V5X A;  2NSG A;  2EPO A;  3EGD B;  4JTC B;  1LE4 A;  3LES A;  5BUO A;  3EH2 A;  2KQ9 A;  2GAQ A;  2WL8 A;  1LVK A;  3J06 A;  2ETS A;  1ZHW A;  5IY5 C;  4B6I A;  4DVZ A;  1QSP A;  4UDV A;  1TWH A;  4YL1 A;  3RF3 A;  2EIL C;  2WB7 A;  3ZSU A;  5JS5 A;  1HMO A;  1V4A A;  1D0X A;  2R9R B;  2R7R A;  4J32 B;  1Z7Q c;  4QI0 A;  1FFT C;  1OXB A;  4LDQ A;  4IWB A;  4BJ6 A;  4EKW A;  4Q5S F;  5T3T A;  4MVM A;  2LSE A;  2HZ8 A;  3MYI A;  1O87 A;  3MX3 A;  3A9C A;  4IB4 A;  4U5E E;  2Q9C A;  4I44 A;  3WHN A;  2KJG A;  2MYS A;  2RD9 A;  5KYW A;  2YL0 A;  3W4Y A;  1M2V A;  1G4W R;  3FDQ A;  2J9W A;  4ER9 A;  4OIP F;  3KYI A;  2GWW A;  4QI2 A;  2HS5 A;  2J9V A;  2LCH A;  3DJU B;  1VYK A;  4L6R A;  1AEP A;  3NYL A;  4XTK A;  2H7O A;  5HSW A;  3VRC A;  2LD6 A;  4JRZ A;  2XXA B;  3T4R A;  2YLD A;  5L0G A;  1Q0G A;  1HW1 A;  1YAU O;  3F47 A;  2GFH A;  2YL7 A;  1IW7 F;  1QQ3 A;  2JD3 A;  2W4M A;  1BR1 A;  2EPK X;  2XS1 A;  3E9V A;  4JTA B;  2IYL D;  2NSF A;  5DQT A;  2BE5 F;  1E86 A;  2HKV A;  2DI3 A;  2VCC A;  3UGP A;  4YT2 A;  4XLP F;  1R5I D;  4MVZ A;  1JMW A;  4EWC A;  3WG7 C;  1ZW2 A;  2H7B A;  4FES A;  4U5B E;  5A6J A;  3L34 A;  4J30 B;  4NCQ A;  2A0B A;  4PK4 A;  3UMK A;  3NDB B;  2IXM A;  3ABM C;  4KNV A;  5K0I A;  1TWG A;  2Y3D A;  4MQ9 F;  3S28 A;  4Z9H A;  2C04 A;  2OEV A;  2Q9A A;  1JAF A;  3QW1 A;  4YJW A;  3K6B A;  4DBR A;  2R7Q A;  4KBL A;  4ULW A;  3W2V A;  4HFF B;  4O6M A;  1A0B A;  1O5H A;  2A6H F;  2G3V A;  2ZD9 A;  3HLZ A;  4ZLC A;  1WTY A;  3ASO C;  1LS1 A;  1YDI A;  1YVI A;  1FAP B;  1CGN A;  2VCB A;  3CQZ A;  4P9T A;  2YQY A;  5E3A A;  4JW1 A;  3AGT A;  3L1M A;  3OWT A;  5DS4 A;  3JSE O;  4FX5 A;  4CJG A;  5COF A;  2NUP A;  3ZVR A;  4LLE A;  1HW2 A;  2KW3 C;  3ASN C;  2A68 F;  5L3V A;  4J7T A;  3FVY A;  3HTK C;  4K1O A;  5JRA A;  2R05 A;  1MMD A;  1W2W A;  3V5Z A;  1HY5 A;  3SXK A;  5B3I A;  3ATP A;  2HJM A;  2EIJ C;  2JPU A;  1OCR C;  2J9U A;  4X0R A;  3TUL A;  5F5F A;  4I1O B;  5JVE A;  3KH2 A;  1OKK A;  4BPM A;  3RH3 A;  1LI5 A;  1QKR A;  2HFI A;  1EQ1 A;  3N0T A;  4KC9 A;  3O39 A;  3O10 A;  2W9Y A;  4MVQ A;  2R7X A;  2J45 A;  4U5F E;  5KYU B;  2HMQ A;  2PP4 A;  2QLA A;  1QVX A;  3RFY A;  3RVZ A;  4OIQ F;  3M79 A;  2YWA A;  3LS1 A;  4MVS A;  3B0P A;  2P0N A;  5E2Q A;  2CYD A;  2R7O A;  3EG9 A;  5JLI A;  5FCL A;  2R7W A;  3U3B A;  3E70 C;  1DOW A;  4CS8 A;  1FMV A;  1RKE B;  4RDA A;  5KYX B;  3ZQV A;  4U5G A;  3L8J A;  3ABK C;  4D4X A;  3C7J A;  2DGJ A;  1I4Z A;  5B1A C;  1C03 A;  2CNW D;  3A11 A;  1JPJ A;  4FWV A;  5CIV A;  2AWC A;  3KMI A;  3LEV A;  4P6I C;  2HSQ A;  3C63 A;  1VB5 A;  1YYX A;  2WZF A;  4JUR I;  3IPM O;  4MND A;  3NRH A;  5L0I A;  1OW8 A;  2VB6 A;  4Q7C A;  1K04 A;  1MNE A;  1Z5Z A;  3POV A;  3KKB A;  4O6N A;  3DE8 A;  4GEH A;  4PJM A;  4YT8 A;  1OCC C;  3R7C A;  1T5O A;  1V74 B;  3I5Q A;  2JX0 A;  3VM6 A;  2J7P A;  2PNO A;  1G5Z A;  3T9O A;  3JTL O;  4JVS A;  2R7T A;  2HUJ A;  2XLO A;  1KTM A;  1ZHX A;  2J8W A;  3GWN A;  5TJ5 E;  2J9B A;  2HJ3 A;  1ZVZ A;  3GM1 A;  5JT4 A;  3JRM O;  2GA0 A;  2H7V C;  4E0H A;  5F5H A;  2Y3G A;  1CPR A;  4RD9 A;  3X2Q C;  4OIO F;  3IQ5 A;  3NG1 A;  2WZL A;  4O7G A;  1MMG A;  1MMA A;  1D0Z A;  1AVO B;  2WZG A;  1HMD A;  1Y4C A;  2EIN C;  2XL8 A;  3DM9 B;  3RKO F;  2OOC A;  2ZXW C;  4NC3 A;  5L0H A;  1ST6 A;  1FR0 A;  4AL1 A;  1RJ9 B;  3N24 A;  2AVK A;  4CS8 C;  4DRJ B;  2XRH A;  1T01 A;  4OD5 A;  3EQL F;  5D91 A;  4MW3 A;  2MWQ A;  4E17 A;  3JYY A;  1H7I A;  2XLW A;  2HSB A;  4N6C A;  4R32 A;  4XEF A;  1Z23 A;  2ASR A;  3LS0 A;  3EJN A;  3HJC A;  3QW0 A;  3K33 A;  1UG7 A;  4YN0 B;  2IXP A;  4A4A A;  4CS7 A;  1F1M A;  3B29 A;  4YL0 A;  4CX9 A;  3TJ6 A;  3AQB A;  1T6I A;  2XL6 A;  4O6Y A;  1APC A;  4G7O F;  4LDR A;  3DI5 A;  3DM5 A;  4DJ9 A;  1G4U S;  3CAX A;  4AX2 A;  4F4B A;  2PX3 A;  4NY3 A;  5CI9 A;  2OJQ A;  1BBH A;  4AK9 A;  4BEM J;  4EHP A;  3UGO A;  1WOL A;  1KNY A;  4YT5 A;  3RVY A;  1GM5 A;  1VK5 A;  2KNH A;  3DE9 A;  4E18 A;  3GM2 A;  2XLV A;  4I1M A;  1PV3 A;  1DOV A;  1ZHY A;  3RQG A;  4NTB A;  1OW7 A;  1CGM E;  2QUP A;  2VAS A;  2KYH A;  3AJM A;  3FOO A;  1PD1 A;  1NFN A;  1S05 A;  2XL4 A;  3EZI A;  4XQ1 A;  4XWJ A;  5T1D B;  3VF0 A;  5KYW B;  2YVK A;  1M2V B;  1U89 A;  1SF8 A;  3NKD A;  2J46 A;  4DOZ A;  3C62 A;  4JTD B;  4MS2 A;  3TOM A;  1OXK A;  3OA1 A;  2BL2 A;  4Z9J A;  2XLD A;  3GEE A;  4N4W A;  3ZWI A;  1VLT A;  5L0F A;  1VYI A;  3RIP A;  1TQG A;  2W45 A;  1PD0 A;  2I15 A;  3Q7G A;  3DWW A;  4ANJ A;  2P1A A;  3RW0 A;  5T3W A;  3IEE A;  4CIP A;  4CBE A;  1YLM A;  1SZI A;  3BRJ A;  2IXN A;  3DJN B;  3K7D A;  3DD7 A;  1AUE A;  1TKN A;  2Y69 C;  1D1B A;  4IAQ A;  1FTS A;  1VLS A;  3LLI A;  2YL1 A;  2YLI A;  2A0U A;  2NPU A;  1OR2 A;  1WN0 A;  1RCP A;  4G78 A;  5BQH A;  3MYF A;  4AE4 A;  5KYN A;  4IAO A;  2LFF A;  2NUT A;  1WAT A;  1WWP A;  2VC9 A;  4GQH A;  4PFP A;  3UMI A;  2L7A A;  1RMV A;  3Q7L A;  1ORY A;  4WAB A;  4KNW A;  5AC4 A;  3CSK A;  3EHM A;  2YZS A;  1Z63 A;  5KYY A;  1MND A;  2A69 F;  1NLX A;  4LAC B;  4ZLD A;  3U0C A;  3EFO A;  2J0W A;  2OQM A;  4JEA A;  2OU6 A;  1E83 A;  1TFO B;  4WGZ A;  4WJ0 A;  3T6G B;  3V5Y A;  5A6B A;  2WVN A;  2WVQ A;  4E7S A;  2NUP B;  1OKK D;  3GEH A;  1YYJ A;  4CJO A;  3IQT A;  1BZ4 A;  2Q00 A;  3AG3 C;  3HNI A;  1JRA A;  1D1C A;  1Y6D A;  1YA9 A;  2Z15 A;  3GM3 A;  5F28 E;  3GAN A;  2PF4 E;  3SXY A;  3BEH A;  3W2W A;  2A6E F;  2V3C C;  1FFH A;  1LIH A;  1A7E A;  3NKE A;  2ZXO A;  2XLM A;  3EHN A;  3O6X A;  2OG2 A;  2AU5 A;  1TWA A;  4A2N B;  2XM4 A;  1ZW3 A;  5DQZ A;  3QVZ A;  3DKA A;  4BJ5 C;  3RYL A;  1BR2 A;  4JZA A;  3ZTZ A;  5EGY A;  2GDC A;  2I8B A;  2A1D D;  2LIG A;  3UMH A;  4Z9I A;  5COG A;  2IOQ A;  2LK4 A;  2B0H A;  4U5D E;  2PBE A;  3IQ6 A;  4EBK A;  5DLJ A;  4C7O A;  1J8M F;  2HV6 A;  3TOL A;  3EG9 B;  3FMS A;  2DYS C;  1L3P A;  4BG0 A;  3NMI A;  1ZU5 A;  4H54 A;  1EI7 A;  2WVO A;  3HNK A;  3DMD A;  3H2U A;  4EBB A;  3ITF A;  4ULV A;  1V55 C;  4CSA C;  2KSF A;  4XPW A;  3JYH A;  2CDQ A;  1NG1 A;  5E3C A;  1VOM A;  1XZQ A;  5BQI A;  4XPY A;  3S90 A;  3HNL A;  4LDK A;  3SXM A;  4BJ5 A;  2R7S A;  1H9G A;  3B71 A;  3SNH A;  2L6H A;  3R2P A;  4IGG A;  2EIK C;  4HE8 D;  4CIH A;  5A6A A;  4K7B A;  2F22 A;  4MVU A;  3U5S A;  1NBB A;  4G0H A;  1YA7 O;  2D5R B;  3G4X A;  2AP3 A;  3M4B A;  1XZP A;  1YJG A;  3AG2 C;  1LS4 A;  3JZ0 A;  3LNM B;  3EGX A;  1YZA A;  2QE9 A;  3B0U X;  1HE9 A;  2J0X A;  2L6G A;  3AGU A;  3SZR A;  1BR4 A;  4DBQ A;  1E2X A;  3JRT A;  1EKY A;  4IJJ A;  1OCZ C;  1M2O A;  4O79 A;  2FAP B;  2L6F A;  1T6Q A;  2XLH A;  3K1H A;  3B9Q A;  4KI2 A;  3C8G A;  1YAR O;  3W8I A;  1CPQ A;  3T6B A;  1GGQ A;  2YHS A;  4EIY A;  3HKK A;  3I4U A;  2EPN A;  4JKV A;  1RKC A;  4IAR A;  3PHF 2;  2CNW A;  4AL0 A;  1V54 C;  2EPM X;  1LE2 A;  1Q0F A;  5JUA A;  4YL3 A;  4BJT A;  1SMY F;  2D4U A;  4ONS A;  2UUH A;  4Q4Z F;  1QLE C;  4I3M A;  4C3B A;  5EK0 A;  5L0D A;  4DVY P;  3V7O A;  3OEO A;  1ORS C;  3WAQ A;  1E84 A;  3MBG A;  2P7V A;  1XWJ A;  3H65 A;  1NU7 D;  2Q9B A;  1K05 A;  1UFB A;  4DRH B;  5CI8 A;  3VAY A;  5L0C A;  2QY9 A;  3ZIB A;  1LPE A;  3MFN A;  1A41 A;  3QZC A;  1D1A A;  2P61 A;  3LLK A;  4MVO A;  2AWY A;  1Z3I X;  2VH3 A;  1H6G A;  1JR8 A;  1EA8 A;  5E33 A;  3JSZ A;  1WGW A;  4PAC A;  4GYT A;  4C3D A;  3EGD A;  3Q6M A;  2X0C A;  1U0B B;  1SR2 A;  3AOU A;  1A7V A;  3EZH A;  3ZC4 A;  3ZTM A;  2P6V A;  4OIN F;  1VMA A;  2CGE A;  2ICW G;  2R7U A;  2OJE D;  1MMN A;  2R7V A;  5AGF A;  4C3E A;  2XLE A;  1OQC A;  2R03 A;  2CCY A;  4JCH A;  1H9T A;  1RXQ A;  1YZC A;  1GS9 A;  2Y3H A;  3W8H A;  4W8K A;  3GWL A;  1M56 C;  1M6T A;  3S27 A;  3CEX A;  4HFK B;  1PCX A;  1N1C A;  3QVY A;  4G7H F;  2OKU A;  3ABL C;  2MHR A;  3RQF A;  1KU2 A;  2NG1 A;  2CW0 F;  5A6K A;  3S84 A;  4N6H A;  4BJ1 A;  2HV7 A;  1OW6 A;  3F46 A;  1S7Z A; 
#chains in the Genus database with same CATH homology
 3HKK A;  5K0I A;  5HV9 A;  4BPM A;  4AL0 A;  4AL1 A;  4JCZ A;  4YL3 A;  4NTB A;  2UUH A;  5BQI A;  4YK5 A;  4JC7 A;  5BQH A;  2UUI A;  4JRZ A;  3PCV A;  4YL0 A;  3B29 A;  4NTA A;  2PNO A;  5BQG A;  4WAB A;  2Q7R A;  4YL1 A;  4J7T A;  3LEO A;  2H8A A;  4NTF A;  3DWW A;  4J7Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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