4FAPB

Atomic structures of the rapamycin analogs in complex with both human fkbp12 and frb domain of frap
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
94
structure length
94
Chain Sequence
VAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRIS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution.
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords FK506-BINDING PROTEIN
total genus 38
structure length 94
sequence length 94
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 1999-05-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.150 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) FKBP12-rapamycin binding domain 4fapB00
2GAQA 5GPGB 2NPUA 4DRJB 2RSEB 1FAPB 4DRIB 1NSGB 2FAPB 1AUEA 4DRHB 4FAPB 3FAPB
chains in the Genus database with same CATH superfamily
3W4YA 4BJ5C 3GEEA 3U2MA 3FMSA 1WGWA 1LE4A 1OCOC 3EHNA 1CPQA 3I5QA 4PJLA 3DD7A 5IY5C 1TWGA 4U5CE 1Z63A 3GM3A 4IWBA 4NTAA 1FFTC 3EZIA 1WATA 1YYJA 2ZXPA 3FOPA 5A69A 1ORYA 5L3QA 4ER9A 1ZHYA 4C3DA 1NBBA 2A6EF 2LFDA 2OJQA 4BJ1A 2P0NA 2ZXRA 4GQHA 4OIRF 3R2PA 3SXZA 3EFOA 5TJ5E 3WHNA 1EKYA 2ASRA 2CNWD 2H7BA 1ORJA 2V26A 3ZWIA 3K1IA 1W2WA 1JPJA 1D1AA 4ZLCA 3QW1A 1FFHA 4JTDB 3FAPB 4GEHA 3UMIA 4OIPF 3MYFA 3ZQVA 4MTOA 2XS1A 4YT5A 2EIJC 4FWVA 4KI2A 1IW7F 1SZIA 3U8VA 1O87A 3QMKA 4MVSA 4U9EA 4AE4A 2R7WA 1K40A 1G5ZA 4IRUA 1HE1A 5BQIA 2MWQA 3NYLA 1JOGA 1Z23A 1M2VA 3EH1A 3PDMP 1OCCC 3U0CA 2PFDA 3ABMC 1J8YF 1GS9A 2HUJA 3NRHA 4JTCB 1YJGA 4IGGA 3S9OA 3SP1A 1L7CA 3SYNA 3X2QC 1WASA 5KYWA 2HMQA 1JAFA 1Z6AA 3ZVRA 3J06A 2IOQA 1OW8A 1HY5A 4PJMA 3PHF2 2IYLD 3DJUB 2Q00A 3C63A 3EH2A 2JPUA 4PACA 5EGYA 3S84A 5DLJA 3E70C 4JEBA 1VMAA 3AOUA 4BPMA 3C8GB 1V4AA 1A0BA 1WTYA 1YZCA 3IHUA 3K1IC 4HFFB 1RMVA 256BA 2P1AA 4CJGA 4CX9A 4A2NB 2XXAB 3TOLA 2QE9A 5T3WA 4NQFA 2CGEA 3L8JA 1UG7A 3OA1A 4LDKA 5KYUB 1MNEA 3GEHA 3DE8A 4IJJA 1OKKA 2EIKC 5L0CA 1J8MF 3ZQYA 3ITFA 4IAOA 5EK0A 4DXWA 3FXHA 3K6BA 4Z9JA 2J9WA 4UDVA 1RJ9A 1CGNA 2QLAA 1GM5A 1ZW2A 4EUKB 5BUOA 4U5DE 4MTFA 5EHHA 2WVNA 1A7DA 3AQCA 5L0JA 3HLZA 3KYIA 1E83A 1A41A 1Z5ZA 2PF4E 5DQZA 2L6FA 4EBJA 2XM0A 1FNTc 3EGDA 2GWWA 3C18A 2NSFA 3TD7A 4K0DA 1VB5A 3K33A 3EJNA 3LNMB 4YT4A 4CS7A 1RJ9B 5E3CA 2V3CC 4C7OB 1GQAA 2LP4A 2VCBA 3KKBA 1MMDA 2OJED 3HNJA 2KGOA 4O6MA 2H7OA 2YZSA 4JVSA 3B0PA 1H9TA 3M15A 1PCXA 5JP7A 3UMHA 5D92A 4E0HA 5L0HA 1OCRC 1VK5A 3GM2A 4QDLA 2J0WA 3AG2C 5E33A 3JRTA 1QVXA 2WVQA 4N4WA 2VCCA 3ZTMA 2EINC 5B3SC 3KH2A 3H65A 1LPEA 4KBLA 2IXMA 2EPLX 4L6RA 2CNWA 3K7DA 4HFKB 3VM6A 4Q7CA 1EQ1A 3OEOA 5L0FA 3N24A 1I4YA 4KC9A 3RIPA 3IQ6A 1O3UA 2J7PD 4K1OA 5COMA 2A1DD 2FGYA 4OINF 1D1BA 4O79A 2O9XA 4WGZA 2W9YA 4O6YA 1MNDA 3JT1A 3S29A 1M57C 3SNHA 1VYKA 2NUPB 2HSBA 4Z9IA 5T3TA 2R9RB 3IPMO 3T6BA 3VAYA 3HJCA 4H4KC 2WB7A 4BJ5A 2OQMA 2X51A 2R7RA 3NKDA 2A69F 1FR0A 3DKAA 1FMVA 4JW1A 2J9BA 1A7VA 3RF3A 1XZQA 2XXAA 1U0BB 3KPHA 3HKKA 3AG4C 3ASOC 2GA0A 5A6KA 3AG3C 1E84A 5KYXB 2KK1A 3NDBB 4N06A 1R4TA 2J0XA 2J9VA 1TWCA 2NSGA 1YA7O 2OEVA 1MQVA 4PFOA 2KNHA 1NU7D 3F47A 4ONSA 2BL2A 4XPWA 5JRAA 2HV6A 5AC5A 4DJ9A 1D0XA 1SR2A 2C04A 5A6BA 3PMRA 4OD4A 5A6AA 2W4MA 3LESA 4JURI 1JRAA 2R25A 2X0CA 4BEJA 2HJ3A 3IEEA 5JS5A 2XLHA 1O5HA 3C62A 3GODA 4JEAA 1VYIA 3AG1C 4MTGA 5JUAA 4BG0A 5DS5A 2YLDA 3L8IA 3ASNC 4J30B 2HJMA 4YK5A 3ZIBA 4Q4ZF 5JVEA 1CGOA 4R32A 2WL8A 2HS5A 5BQGA 3C8ZA 4PR9A 4JZAA 1QQ3A 2GAQA 1MMAA 4PJNA 3VYWA 2Y3HA 2TMVP 2J46A 5F5FA 1M6TA 2KJGA 4JCZA 3U8PA 4U5BE 4YL1A 4CDVA 1E85A 1T6UA 2YLGA 3QZCA 4CBEA 4P9FA 1Q0GA 3B0UX 5JLIA 4YJWA 4GYTA 2WZGA 4JJFA 4XPYA 1FAPB 2ZXWC 3EQLF 4KNVA 4Q5SF 1BR4A 2KSFA 2L6GA 2R7QA 4NTFA 3RH3A 1OW7A 3T6JA 1OXBA 3V7OA 4YL0A 4MVOA 1LE2A 4AL1A 2HV7A 4DRJB 3TULA 1PD1A 2KYHA 2PX0A 2VASA 4P9TA 2ZD9A 4G0HA 4XQ1A 3LS1A 4CS8A 4F4BA 1K05A 1ORSC 4LDQA 3EFOB 1TR2A 2I8BA 5DS6A 3LLKA 2R02A 2LK4A 3I4UA 5COGA 4JIOA 3SXYA 2R7UA 2L9JA 3IQ5A 5B3IA 1YDIA 1AEPA 2YL3A 1ZVZA 2RD9A 1VTMP 1HMOA 4E0IA 2EIMC 2IXNA 2Q9AA 3SEOA 1ST6A 1V55C 2NUTA 2PP4A 3W8HA 4MQ9F 1Y6DA 2EPMX 2P6VA 3X1OA 3B9QA 2G3VA 3DM5A 2FAPB 2JX0A 3UNGC 4AE4B 1LS1A 1G4US 3NYJA 4NY3A 4OD5A 2XL6A 3CEXA 4EWCA 5KYNA 4MW3A 3HNKA 1M2VB 2QNLA 1DOVA 1I4ZA 2VB6A 1YA9A 3AGUA 4FAPB 2B0JA 4G7HF 3GWNA 1TWHA 5KYWB 1U89A 2M4EA 2NUTB 3PCVA 4IARA 4MVQA 2B0HA 2Y3DA 3B29A 4ULWA 4HE8D 5HSWA 4CS8C 2DB4A 4ULVA 3NKEA 2Q7RA 3LEOA 3RW0A 2Q9CA 4D4NA 3AQBA 1VLTA 2I15A 1U6HA 2PBEA 1Q0FA 5E3AA 3U9JA 1RKCA 4DBQA 4WGYA 4B6IA 5L0DA 4I3MA 4J7YA 2AU5A 4XEVA 3EG9A 5B1BC 3TOMA 3LEVA 3O39A 4CS9A 5DS4A 3KMIA 4H54A 3M1CB 5T1DB 2XLDA 3VRCA 4JE9A 3FDQA 3DZAA 1LVKA 2EILC 1HE9A 2C03A 1QPUA 1T5OA 2CYDA 2UUIA 2XLVA 3KYJA 1LS4A 4LLEA 2XL4A 3FOOA 4U5GA 3DMDA 4O7GA 3SXKA 4LACB 2YKZA 3GM1A 4U5EE 1LKXA 3LJBA 3G4ZA 2E87A 3WODF 3O6XA 4MVZA 2VCAA 1YZAA 4YT8A 3EGDB 2YL0A 2R7OA 3BRJA 2A6HF 3IQCA 1ZHTA 4JC7A 3QVZA 2QY9A 2A0UA 4CIHA 2OG2A 4NC3A 3DAGA 3LUTB 3JZ0A 1R5ID 3Q7LA 3JRMO 1N1CA 3K66A 3QW0A 4X0RA 1GGQA 2MHRA 1QSPA 3V5ZA 2J8WA 4CS9C 2G3KA 2EPNA 3DAFA 4YN0B 4EBKA 4EHPA 1F1MA 2LIGA 3EGXA 2WVOA 4N6HA 1I5NA 2KQ9A 3NMJA 3QVYA 5K0IA 3S0XA 2R05A 3NMKA 3UMKA 3FVYA 1QKRA 1H9GA 3MYIA 2HMZA 4I44A 4U5FE 4ZLDA 4IAQA 2UUHA 1V54C 3E9VA 4N6CA 1JPNA 3ZDLA 1HW2A 3U5SA 1WOLA 1FTSA 3H2VA 4XWJA 3POVA 3QTHA 2CCYA 2XRHA 4BJ6C 2L81A 4JKVA 1Z7Qc 1ZYRF 3C8GD 1RKEA 2XLWA 4AX2A 5JT4A 3EPVA 2PNOA 1TKNA 3V5YA 3MLGA 3VF0A 5KYYA 2OCCC 2R03A 2YRFA 5F28E 3W8IA 2IBFA 2WZLA 2XS8A 1NSGB 3RQEA 3BEHA 4DBRA 2JD3A 3M4BA 1E86A 2GFHA 1S7ZA 4XEFA 4ANJA 2G62A 3EZHA 2D4UA 1OR2A 2D5RB 4W8KA 2XLOA 1AUEA 4PFPA 1WWPA 2DGJA 1BDJB 2Y39A 2OEXA 4XEKA 3LAYA 1Q0DA 1M2OA 3L34A 1KU2A 2EPOA 1XZPA 3OWTA 4FESA 3UGOA 1OKKD 3U9MA 1ZU5A 2CDQA 5FCLA 3LNRA 2YEVA 3CQZA 2LCHA 1VOMA 2M64A 3NG1A 3B0VC 2YHSA 1EI7A 3DM9B 3ZTZA 4CJOA 1OCZC 2ZPAA 2W45A 4J7TA 3GANA 3ATPA 1HW1A 3Q6NA 1L3PA 1MMGA 4G7ZF 1T6QA 2HZ8A 1T9KA 4CDYA 4JCHA 2RSEB 3AJMA 3RQGA 3Q6MA 4EIYA 2DI3A 1CGME 1MMNA 4U9DA 3RYLA 3SZRA 3JSZA 3TJ6A 1LI7A 5E2QA 3CZ6A 2LD6A 2Y69C 1JR8A 2LSEA 3W2WA 1NG1A 1LM3B 4RBNA 1ZU4A 3GEIA 3W2VA 2F22A 3FAJA 3JYHA 1AVOB 2AWYA 2R7TA 2MYSA 2Z15A 3I5PA 4LDRA 2R7XA 3H2UA 4JRZA 2Y3BA 2Q3TA 3DWWA 2HSQA 4YL3A 3U3BA 3V5XA 4DRIB 2KW3C 1A7EA 2LFFA 4A4AA 3M79A 1KNYA 3RVYA 4DRHB 2J7PA 3L1MA 3JCUQ 2Y3GA 3DI5A 3FHDA 3ZG1A 1OW6A 1ZZPA 4HEAJ 4XPXA 4PJJA 1ZHWA 1YARO 1D0YA 4XLNF 2YWAA 1G4WR 1BR1A 2GDCA 2ICWG 2R7VA 3UGPA 1LIHA 1UFBA 2J9UA 1EA8A 5D91A 1T6IA 5CI8A 2IXPA 3O10A 2ZXOA 1YLMA 3RKOF 5CIVA 4QI2A 1Z3IX 5AGFA 1Q0MA 2Q9BA 3R7CA 3C8GA 4XTKA 1QZXA 3T4RA 3WG7C 3T9OA 3UR3C 4C3BA 4E17A 2ETSA 1BR2A 3TJ5A 5L0IA 1SMYF 5KYUA 2EPKX 1YYXA 4I1OB 4YT2A 2YLIA 4XLPF 1SYQA 4NTBA 2NPUA 3N2ZB 4OIQF 4RDAA 1C17M 1VLSA 1XWJA 2YL7A 3A9CA 3ABLC 4MNDA 3U3FA 4P6IC 3NYMA 1BBHA 2XLEA 3CAXA 4FX5A 1FMWA 1Q0KA 3CSKA 3DXJF 3ABKC 5A6BD 2YVKA 1PV3A 5DVWA 3B71A 4AL0A 1CPRA 1C02A 3AGTA 1DOWA 2IXOA 3HNIA 5JSLA 3EG9B 1WN0A 5B1AC 4CIPA 2W4BA 5HV9A 2NG1A 2KC3A 3HTKC 5L0GA 2AVKA 4BJ6A 3TK0A 1OR3A 4C7OA 2DYRC 3N0TA 1KTMA 3A11A 2XL8A 3C7JA 3MFNA 4IB4A 4C3EA 1M56C 1NFOA 5A6JA 4DOZA 2QTVA 3GWLA 4MVMA 3ECSA 3IQTA 1ZHXA 3M4CA 4QI0A 1NLXA 2HFIA 4D4XA 1ZHZA 1ZW3A 3JYYA 1TFKB 2BE5F 4YWQA 2VC9A 3MBGA 4WJ0A 3U2LA 3WAQA 2DYSC 2H8AA 3US6A 1JMWA 1TFOB 4G78A 3F46A 1HMDA 4E18A 1V74B 3T6GB 1RCPA 4LLCA 3S27A 1LI5A 1OXKA 1PD0A 3DE9A 3SXMA 1C03A 2J45A 3HNLA 4EKWA 4MVUA 3EHMA 1H7IA 2R7SA 3EGXB 3L0IA 2NUPA 4WABA 5COFA 3ZSUA 2BC5A 2CW0F 2Q4FA 1T01A 1NU9C 2AP3A 4I1MA 3JSEO 3RQFA 2LQGA 4RD9A 3Q7GA 2AWCA 4W8PA 2IM8A 3O55A 4Z9HA 2OKUA 3TQOA 1TQGA 4J32B 2HKVA 3MX3A 3ZC4A 1YVIA 1APCA 4MVRA 2H7VC 4DVYP 4BJTA 2A0BA 1G8XA 5L3VA 4CSAA 1QLEC 2XM4A 1B68A 3LS0A 4E7SA 5AC4A 5KYXA 2FFHA 2OU6A 2XLMA 4MS2A 1RKEB 4KNWA 4JJGA 5BQHA 4OIOF 3JTLO 4E7ZA 4K7BA 1K04A 2YQYA 3RFYA 5KYYB 1D1CA 1H6GA 4JTAB 4NCQA 3DJNB 4G7OF 2A68F 2OOCA 1D0ZA 3S28A 3NMIA 2PX3A 4MW8A 3S90A 1IZMA 2P61A 4M63A 2VH3A 4U5HA 5GPGB 2XSEA 1E2XA 5DQTA 4LERA 3K1HA 1NZEA 1Y4CA 1YAUO 1NFNA 2L7AA 3LLIA 4DVZA 3G50A 4CDAA 5F5HA 5CI9A 3KL4A 1RXQA 2P7VA 2QUPA 4AK9A 1BZ4A 2YL1A 4O6NA 4EBBA 2WZFA 1OQCA 4PK4A 5FZTA 3GORA 1SF8A 4CSAC 1S05A 3G4XA 4BEMJ 3RVZA 1TWAA 2L6HA
chains in the Genus database with same CATH topology
2GAQA 5GPGB 2NPUA 4DRJB 2RSEB 1FAPB 4DRIB 1NSGB 2FAPB 1AUEA 4DRHB 4FAPB 3FAPB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GAQ A;  5GPG B;  2NPU A;  4DRJ B;  2RSE B;  1FAP B;  4DRI B;  1NSG B;  2FAP B;  1AUE A;  4DRH B;  4FAP B;  3FAP B; 
#chains in the Genus database with same CATH topology
 3W4Y A;  4BJ5 C;  3GEE A;  3U2M A;  3FMS A;  1WGW A;  1LE4 A;  1OCO C;  3EHN A;  1CPQ A;  3I5Q A;  4PJL A;  3DD7 A;  5IY5 C;  1TWG A;  4U5C E;  1Z63 A;  3GM3 A;  4IWB A;  4NTA A;  1FFT C;  3EZI A;  1WAT A;  1YYJ A;  2ZXP A;  3FOP A;  5A69 A;  1ORY A;  5L3Q A;  4ER9 A;  1ZHY A;  4C3D A;  1NBB A;  2A6E F;  2LFD A;  2OJQ A;  4BJ1 A;  2P0N A;  2ZXR A;  4GQH A;  4OIR F;  3R2P A;  3SXZ A;  3EFO A;  5TJ5 E;  3WHN A;  1EKY A;  2ASR A;  2CNW D;  2H7B A;  1ORJ A;  2V26 A;  3ZWI A;  3K1I A;  1W2W A;  1JPJ A;  1D1A A;  4ZLC A;  3QW1 A;  1FFH A;  4JTD B;  3FAP B;  4GEH A;  3UMI A;  4OIP F;  3MYF A;  3ZQV A;  4MTO A;  2XS1 A;  4YT5 A;  2EIJ C;  4FWV A;  4KI2 A;  1IW7 F;  1SZI A;  3U8V A;  1O87 A;  3QMK A;  4MVS A;  4U9E A;  4AE4 A;  2R7W A;  1K40 A;  1G5Z A;  4IRU A;  1HE1 A;  5BQI A;  2MWQ A;  3NYL A;  1JOG A;  1Z23 A;  1M2V A;  3EH1 A;  3PDM P;  1OCC C;  3U0C A;  2PFD A;  3ABM C;  1J8Y F;  1GS9 A;  2HUJ A;  3NRH A;  4JTC B;  1YJG A;  4IGG A;  3S9O A;  3SP1 A;  1L7C A;  3SYN A;  3X2Q C;  1WAS A;  5KYW A;  2HMQ A;  1JAF A;  1Z6A A;  3ZVR A;  3J06 A;  2IOQ A;  1OW8 A;  1HY5 A;  4PJM A;  3PHF 2;  2IYL D;  3DJU B;  2Q00 A;  3C63 A;  3EH2 A;  2JPU A;  4PAC A;  5EGY A;  3S84 A;  5DLJ A;  3E70 C;  4JEB A;  1VMA A;  3AOU A;  4BPM A;  3C8G B;  1V4A A;  1A0B A;  1WTY A;  1YZC A;  3IHU A;  3K1I C;  4HFF B;  1RMV A;  256B A;  2P1A A;  4CJG A;  4CX9 A;  4A2N B;  2XXA B;  3TOL A;  2QE9 A;  5T3W A;  4NQF A;  2CGE A;  3L8J A;  1UG7 A;  3OA1 A;  4LDK A;  5KYU B;  1MNE A;  3GEH A;  3DE8 A;  4IJJ A;  1OKK A;  2EIK C;  5L0C A;  1J8M F;  3ZQY A;  3ITF A;  4IAO A;  5EK0 A;  4DXW A;  3FXH A;  3K6B A;  4Z9J A;  2J9W A;  4UDV A;  1RJ9 A;  1CGN A;  2QLA A;  1GM5 A;  1ZW2 A;  4EUK B;  5BUO A;  4U5D E;  4MTF A;  5EHH A;  2WVN A;  1A7D A;  3AQC A;  5L0J A;  3HLZ A;  3KYI A;  1E83 A;  1A41 A;  1Z5Z A;  2PF4 E;  5DQZ A;  2L6F A;  4EBJ A;  2XM0 A;  1FNT c;  3EGD A;  2GWW A;  3C18 A;  2NSF A;  3TD7 A;  4K0D A;  1VB5 A;  3K33 A;  3EJN A;  3LNM B;  4YT4 A;  4CS7 A;  1RJ9 B;  5E3C A;  2V3C C;  4C7O B;  1GQA A;  2LP4 A;  2VCB A;  3KKB A;  1MMD A;  2OJE D;  3HNJ A;  2KGO A;  4O6M A;  2H7O A;  2YZS A;  4JVS A;  3B0P A;  1H9T A;  3M15 A;  1PCX A;  5JP7 A;  3UMH A;  5D92 A;  4E0H A;  5L0H A;  1OCR C;  1VK5 A;  3GM2 A;  4QDL A;  2J0W A;  3AG2 C;  5E33 A;  3JRT A;  1QVX A;  2WVQ A;  4N4W A;  2VCC A;  3ZTM A;  2EIN C;  5B3S C;  3KH2 A;  3H65 A;  1LPE A;  4KBL A;  2IXM A;  2EPL X;  4L6R A;  2CNW A;  3K7D A;  4HFK B;  3VM6 A;  4Q7C A;  1EQ1 A;  3OEO A;  5L0F A;  3N24 A;  1I4Y A;  4KC9 A;  3RIP A;  3IQ6 A;  1O3U A;  2J7P D;  4K1O A;  5COM A;  2A1D D;  2FGY A;  4OIN F;  1D1B A;  4O79 A;  2O9X A;  4WGZ A;  2W9Y A;  4O6Y A;  1MND A;  3JT1 A;  3S29 A;  1M57 C;  3SNH A;  1VYK A;  2NUP B;  2HSB A;  4Z9I A;  5T3T A;  2R9R B;  3IPM O;  3T6B A;  3VAY A;  3HJC A;  4H4K C;  2WB7 A;  4BJ5 A;  2OQM A;  2X51 A;  2R7R A;  3NKD A;  2A69 F;  1FR0 A;  3DKA A;  1FMV A;  4JW1 A;  2J9B A;  1A7V A;  3RF3 A;  1XZQ A;  2XXA A;  1U0B B;  3KPH A;  3HKK A;  3AG4 C;  3ASO C;  2GA0 A;  5A6K A;  3AG3 C;  1E84 A;  5KYX B;  2KK1 A;  3NDB B;  4N06 A;  1R4T A;  2J0X A;  2J9V A;  1TWC A;  2NSG A;  1YA7 O;  2OEV A;  1MQV A;  4PFO A;  2KNH A;  1NU7 D;  3F47 A;  4ONS A;  2BL2 A;  4XPW A;  5JRA A;  2HV6 A;  5AC5 A;  4DJ9 A;  1D0X A;  1SR2 A;  2C04 A;  5A6B A;  3PMR A;  4OD4 A;  5A6A A;  2W4M A;  3LES A;  4JUR I;  1JRA A;  2R25 A;  2X0C A;  4BEJ A;  2HJ3 A;  3IEE A;  5JS5 A;  2XLH A;  1O5H A;  3C62 A;  3GOD A;  4JEA A;  1VYI A;  3AG1 C;  4MTG A;  5JUA A;  4BG0 A;  5DS5 A;  2YLD A;  3L8I A;  3ASN C;  4J30 B;  2HJM A;  4YK5 A;  3ZIB A;  4Q4Z F;  5JVE A;  1CGO A;  4R32 A;  2WL8 A;  2HS5 A;  5BQG A;  3C8Z A;  4PR9 A;  4JZA A;  1QQ3 A;  2GAQ A;  1MMA A;  4PJN A;  3VYW A;  2Y3H A;  2TMV P;  2J46 A;  5F5F A;  1M6T A;  2KJG A;  4JCZ A;  3U8P A;  4U5B E;  4YL1 A;  4CDV A;  1E85 A;  1T6U A;  2YLG A;  3QZC A;  4CBE A;  4P9F A;  1Q0G A;  3B0U X;  5JLI A;  4YJW A;  4GYT A;  2WZG A;  4JJF A;  4XPY A;  1FAP B;  2ZXW C;  3EQL F;  4KNV A;  4Q5S F;  1BR4 A;  2KSF A;  2L6G A;  2R7Q A;  4NTF A;  3RH3 A;  1OW7 A;  3T6J A;  1OXB A;  3V7O A;  4YL0 A;  4MVO A;  1LE2 A;  4AL1 A;  2HV7 A;  4DRJ B;  3TUL A;  1PD1 A;  2KYH A;  2PX0 A;  2VAS A;  4P9T A;  2ZD9 A;  4G0H A;  4XQ1 A;  3LS1 A;  4CS8 A;  4F4B A;  1K05 A;  1ORS C;  4LDQ A;  3EFO B;  1TR2 A;  2I8B A;  5DS6 A;  3LLK A;  2R02 A;  2LK4 A;  3I4U A;  5COG A;  4JIO A;  3SXY A;  2R7U A;  2L9J A;  3IQ5 A;  5B3I A;  1YDI A;  1AEP A;  2YL3 A;  1ZVZ A;  2RD9 A;  1VTM P;  1HMO A;  4E0I A;  2EIM C;  2IXN A;  2Q9A A;  3SEO A;  1ST6 A;  1V55 C;  2NUT A;  2PP4 A;  3W8H A;  4MQ9 F;  1Y6D A;  2EPM X;  2P6V A;  3X1O A;  3B9Q A;  2G3V A;  3DM5 A;  2FAP B;  2JX0 A;  3UNG C;  4AE4 B;  1LS1 A;  1G4U S;  3NYJ A;  4NY3 A;  4OD5 A;  2XL6 A;  3CEX A;  4EWC A;  5KYN A;  4MW3 A;  3HNK A;  1M2V B;  2QNL A;  1DOV A;  1I4Z A;  2VB6 A;  1YA9 A;  3AGU A;  4FAP B;  2B0J A;  4G7H F;  3GWN A;  1TWH A;  5KYW B;  1U89 A;  2M4E A;  2NUT B;  3PCV A;  4IAR A;  4MVQ A;  2B0H A;  2Y3D A;  3B29 A;  4ULW A;  4HE8 D;  5HSW A;  4CS8 C;  2DB4 A;  4ULV A;  3NKE A;  2Q7R A;  3LEO A;  3RW0 A;  2Q9C A;  4D4N A;  3AQB A;  1VLT A;  2I15 A;  1U6H A;  2PBE A;  1Q0F A;  5E3A A;  3U9J A;  1RKC A;  4DBQ A;  4WGY A;  4B6I A;  5L0D A;  4I3M A;  4J7Y A;  2AU5 A;  4XEV A;  3EG9 A;  5B1B C;  3TOM A;  3LEV A;  3O39 A;  4CS9 A;  5DS4 A;  3KMI A;  4H54 A;  3M1C B;  5T1D B;  2XLD A;  3VRC A;  4JE9 A;  3FDQ A;  3DZA A;  1LVK A;  2EIL C;  1HE9 A;  2C03 A;  1QPU A;  1T5O A;  2CYD A;  2UUI A;  2XLV A;  3KYJ A;  1LS4 A;  4LLE A;  2XL4 A;  3FOO A;  4U5G A;  3DMD A;  4O7G A;  3SXK A;  4LAC B;  2YKZ A;  3GM1 A;  4U5E E;  1LKX A;  3LJB A;  3G4Z A;  2E87 A;  3WOD F;  3O6X A;  4MVZ A;  2VCA A;  1YZA A;  4YT8 A;  3EGD B;  2YL0 A;  2R7O A;  3BRJ A;  2A6H F;  3IQC A;  1ZHT A;  4JC7 A;  3QVZ A;  2QY9 A;  2A0U A;  4CIH A;  2OG2 A;  4NC3 A;  3DAG A;  3LUT B;  3JZ0 A;  1R5I D;  3Q7L A;  3JRM O;  1N1C A;  3K66 A;  3QW0 A;  4X0R A;  1GGQ A;  2MHR A;  1QSP A;  3V5Z A;  2J8W A;  4CS9 C;  2G3K A;  2EPN A;  3DAF A;  4YN0 B;  4EBK A;  4EHP A;  1F1M A;  2LIG A;  3EGX A;  2WVO A;  4N6H A;  1I5N A;  2KQ9 A;  3NMJ A;  3QVY A;  5K0I A;  3S0X A;  2R05 A;  3NMK A;  3UMK A;  3FVY A;  1QKR A;  1H9G A;  3MYI A;  2HMZ A;  4I44 A;  4U5F E;  4ZLD A;  4IAQ A;  2UUH A;  1V54 C;  3E9V A;  4N6C A;  1JPN A;  3ZDL A;  1HW2 A;  3U5S A;  1WOL A;  1FTS A;  3H2V A;  4XWJ A;  3POV A;  3QTH A;  2CCY A;  2XRH A;  4BJ6 C;  2L81 A;  4JKV A;  1Z7Q c;  1ZYR F;  3C8G D;  1RKE A;  2XLW A;  4AX2 A;  5JT4 A;  3EPV A;  2PNO A;  1TKN A;  3V5Y A;  3MLG A;  3VF0 A;  5KYY A;  2OCC C;  2R03 A;  2YRF A;  5F28 E;  3W8I A;  2IBF A;  2WZL A;  2XS8 A;  1NSG B;  3RQE A;  3BEH A;  4DBR A;  2JD3 A;  3M4B A;  1E86 A;  2GFH A;  1S7Z A;  4XEF A;  4ANJ A;  2G62 A;  3EZH A;  2D4U A;  1OR2 A;  2D5R B;  4W8K A;  2XLO A;  1AUE A;  4PFP A;  1WWP A;  2DGJ A;  1BDJ B;  2Y39 A;  2OEX A;  4XEK A;  3LAY A;  1Q0D A;  1M2O A;  3L34 A;  1KU2 A;  2EPO A;  1XZP A;  3OWT A;  4FES A;  3UGO A;  1OKK D;  3U9M A;  1ZU5 A;  2CDQ A;  5FCL A;  3LNR A;  2YEV A;  3CQZ A;  2LCH A;  1VOM A;  2M64 A;  3NG1 A;  3B0V C;  2YHS A;  1EI7 A;  3DM9 B;  3ZTZ A;  4CJO A;  1OCZ C;  2ZPA A;  2W45 A;  4J7T A;  3GAN A;  3ATP A;  1HW1 A;  3Q6N A;  1L3P A;  1MMG A;  4G7Z F;  1T6Q A;  2HZ8 A;  1T9K A;  4CDY A;  4JCH A;  2RSE B;  3AJM A;  3RQG A;  3Q6M A;  4EIY A;  2DI3 A;  1CGM E;  1MMN A;  4U9D A;  3RYL A;  3SZR A;  3JSZ A;  3TJ6 A;  1LI7 A;  5E2Q A;  3CZ6 A;  2LD6 A;  2Y69 C;  1JR8 A;  2LSE A;  3W2W A;  1NG1 A;  1LM3 B;  4RBN A;  1ZU4 A;  3GEI A;  3W2V A;  2F22 A;  3FAJ A;  3JYH A;  1AVO B;  2AWY A;  2R7T A;  2MYS A;  2Z15 A;  3I5P A;  4LDR A;  2R7X A;  3H2U A;  4JRZ A;  2Y3B A;  2Q3T A;  3DWW A;  2HSQ A;  4YL3 A;  3U3B A;  3V5X A;  4DRI B;  2KW3 C;  1A7E A;  2LFF A;  4A4A A;  3M79 A;  1KNY A;  3RVY A;  4DRH B;  2J7P A;  3L1M A;  3JCU Q;  2Y3G A;  3DI5 A;  3FHD A;  3ZG1 A;  1OW6 A;  1ZZP A;  4HEA J;  4XPX A;  4PJJ A;  1ZHW A;  1YAR O;  1D0Y A;  4XLN F;  2YWA A;  1G4W R;  1BR1 A;  2GDC A;  2ICW G;  2R7V A;  3UGP A;  1LIH A;  1UFB A;  2J9U A;  1EA8 A;  5D91 A;  1T6I A;  5CI8 A;  2IXP A;  3O10 A;  2ZXO A;  1YLM A;  3RKO F;  5CIV A;  4QI2 A;  1Z3I X;  5AGF A;  1Q0M A;  2Q9B A;  3R7C A;  3C8G A;  4XTK A;  1QZX A;  3T4R A;  3WG7 C;  3T9O A;  3UR3 C;  4C3B A;  4E17 A;  2ETS A;  1BR2 A;  3TJ5 A;  5L0I A;  1SMY F;  5KYU A;  2EPK X;  1YYX A;  4I1O B;  4YT2 A;  2YLI A;  4XLP F;  1SYQ A;  4NTB A;  2NPU A;  3N2Z B;  4OIQ F;  4RDA A;  1C17 M;  1VLS A;  1XWJ A;  2YL7 A;  3A9C A;  3ABL C;  4MND A;  3U3F A;  4P6I C;  3NYM A;  1BBH A;  2XLE A;  3CAX A;  4FX5 A;  1FMW A;  1Q0K A;  3CSK A;  3DXJ F;  3ABK C;  5A6B D;  2YVK A;  1PV3 A;  5DVW A;  3B71 A;  4AL0 A;  1CPR A;  1C02 A;  3AGT A;  1DOW A;  2IXO A;  3HNI A;  5JSL A;  3EG9 B;  1WN0 A;  5B1A C;  4CIP A;  2W4B A;  5HV9 A;  2NG1 A;  2KC3 A;  3HTK C;  5L0G A;  2AVK A;  4BJ6 A;  3TK0 A;  1OR3 A;  4C7O A;  2DYR C;  3N0T A;  1KTM A;  3A11 A;  2XL8 A;  3C7J A;  3MFN A;  4IB4 A;  4C3E A;  1M56 C;  1NFO A;  5A6J A;  4DOZ A;  2QTV A;  3GWL A;  4MVM A;  3ECS A;  3IQT A;  1ZHX A;  3M4C A;  4QI0 A;  1NLX A;  2HFI A;  4D4X A;  1ZHZ A;  1ZW3 A;  3JYY A;  1TFK B;  2BE5 F;  4YWQ A;  2VC9 A;  3MBG A;  4WJ0 A;  3U2L A;  3WAQ A;  2DYS C;  2H8A A;  3US6 A;  1JMW A;  1TFO B;  4G78 A;  3F46 A;  1HMD A;  4E18 A;  1V74 B;  3T6G B;  1RCP A;  4LLC A;  3S27 A;  1LI5 A;  1OXK A;  1PD0 A;  3DE9 A;  3SXM A;  1C03 A;  2J45 A;  3HNL A;  4EKW A;  4MVU A;  3EHM A;  1H7I A;  2R7S A;  3EGX B;  3L0I A;  2NUP A;  4WAB A;  5COF A;  3ZSU A;  2BC5 A;  2CW0 F;  2Q4F A;  1T01 A;  1NU9 C;  2AP3 A;  4I1M A;  3JSE O;  3RQF A;  2LQG A;  4RD9 A;  3Q7G A;  2AWC A;  4W8P A;  2IM8 A;  3O55 A;  4Z9H A;  2OKU A;  3TQO A;  1TQG A;  4J32 B;  2HKV A;  3MX3 A;  3ZC4 A;  1YVI A;  1APC A;  4MVR A;  2H7V C;  4DVY P;  4BJT A;  2A0B A;  1G8X A;  5L3V A;  4CSA A;  1QLE C;  2XM4 A;  1B68 A;  3LS0 A;  4E7S A;  5AC4 A;  5KYX A;  2FFH A;  2OU6 A;  2XLM A;  4MS2 A;  1RKE B;  4KNW A;  4JJG A;  5BQH A;  4OIO F;  3JTL O;  4E7Z A;  4K7B A;  1K04 A;  2YQY A;  3RFY A;  5KYY B;  1D1C A;  1H6G A;  4JTA B;  4NCQ A;  3DJN B;  4G7O F;  2A68 F;  2OOC A;  1D0Z A;  3S28 A;  3NMI A;  2PX3 A;  4MW8 A;  3S90 A;  1IZM A;  2P61 A;  4M63 A;  2VH3 A;  4U5H A;  5GPG B;  2XSE A;  1E2X A;  5DQT A;  4LER A;  3K1H A;  1NZE A;  1Y4C A;  1YAU O;  1NFN A;  2L7A A;  3LLI A;  4DVZ A;  3G50 A;  4CDA A;  5F5H A;  5CI9 A;  3KL4 A;  1RXQ A;  2P7V A;  2QUP A;  4AK9 A;  1BZ4 A;  2YL1 A;  4O6N A;  4EBB A;  2WZF A;  1OQC A;  4PK4 A;  5FZT A;  3GOR A;  1SF8 A;  4CSA C;  1S05 A;  3G4X A;  4BEM J;  3RVZ A;  1TWA A;  2L6H A; 
#chains in the Genus database with same CATH homology
 2GAQ A;  5GPG B;  2NPU A;  4DRJ B;  2RSE B;  1FAP B;  4DRI B;  1NSG B;  2FAP B;  1AUE A;  4DRH B;  4FAP B;  3FAP B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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