4J7YA

Human ltc4 synthase in complex with product analogs - implications for enzyme catalysis
Total Genus 58
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
147
structure length
147
Chain Sequence
HHHKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVALAALGLLAHFLPAALRAALLGRLRT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords Leukotriene C4 synthase
total genus 58
structure length 147
sequence length 147
ec nomenclature ec 4.4.1.20: Leukotriene-C(4) synthase.
pdb deposition date 2013-02-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01124 MAPEG MAPEG family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.550 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Membrane associated eicosanoid/glutathione metabolism-like domain 4j7yA00
3PCVA 2PNOA 4YL3A 4YL0A 4NTAA 3DWWA 4YK5A 4YL1A 2H8AA 4JCZA 3B29A 4AL0A 4NTBA 4J7YA 4AL1A 5BQHA 4JRZA 3HKKA 2UUHA 3LEOA 2Q7RA 5K0IA 4JC7A 4BPMA 4J7TA 4NTFA 4WABA 5BQIA 5BQGA 2UUIA 5HV9A
chains in the Genus database with same CATH superfamily
4P9FA 2R03A 2WZFA 4YT5A 1PD0A 3JSZA 4IGGA 2ZPAA 4XEVA 4BJTA 2NUPB 1APCA 2VCBA 2XRHA 1ORSC 2YVKA 3AG1C 4IRUA 5B1BC 4NTAA 3WAQA 2IXMA 5E33A 5AC4A 1F1MA 2VCCA 4MTFA 1ZHWA 3HNKA 4P9TA 1AVOB 3JCUQ 5T3WA 1TWAA 3KPHA 4KBLA 1HW1A 3A9CA 1ZYRF 3I4UA 4CSAC 1E2XA 5L0FA 2XLVA 1T5OA 3EGXB 4D4NA 1I5NA 4JEBA 3V7OA 1QZXA 2OJQA 3T6GB 1L3PA 4N4WA 3W8IA 4LERA 2AWYA 1A7EA 3JRMO 1DOWA 1M2OA 1OW7A 2P6VA 4OIRF 5HV9A 1RJ9A 2IXPA 1ZU4A 2KK1A 3GM3A 4O7GA 3SXYA 4CDYA 4CIHA 3GWLA 3SNHA 3FVYA 3QTHA 3DJUB 3UMIA 3DMDA 2E87A 3B71A 1SZIA 3RQFA 3NYJA 1Z6AA 4YT2A 4HFKB 4MNDA 4C3BA 5L3VA 3W4YA 1B68A 2PBEA 4EKWA 1LKXA 2PF4E 3GANA 1D1CA 4CS7A 3FOOA 4ZLCA 2M4EA 4J32B 5AC5A 3MLGA 2VH3A 3C7JA 4JRZA 3DE9A 4Q5SF 4JE9A 1MNEA 3ZWIA 2WVOA 3NG1A 2J9WA 5FZTA 4AE4A 1OW8A 4JCHA 4BPMA 3X2QC 1UFBA 4Z9IA 1M2VB 3FAJA 2FFHA 5BQIA 2A68F 4XEKA 3ABLC 3WODF 1NU9C 1J8YF 4EWCA 2KW3C 3JYHA 4U9DA 4CDAA 5A6BD 1ZHZA 2EINC 3IPMO 1PCXA 3EJNA 2G3VA 2H7OA 4MW8A 2CDQA 2QUPA 2LFFA 2BE5F 4ANJA 4YT4A 4KNVA 4H54A 5CI8A 5GPGB 4DBRA 5JRAA 1E85A 4XLNF 3OWTA 2KQ9A 4EBBA 1M56C 2EIJC 2EIKC 5L0HA 5KYXA 1YZAA 4CSAA 1O3UA 1UG7A 1Y4CA 2P1AA 3IEEA 3T9OA 1K40A 3EHNA 3U0CA 1FFTC 5DQZA 1Z7Qc 1BBHA 3U3BA 1DOVA 1ZHXA 1JMWA 3HNIA 4H4KC 3R7CA 3RH3A 4E0HA 2JPUA 1SYQA 1ZVZA 2OKUA 3E70C 4JEAA 3NMJA 3RKOF 3EZIA 2Q9CA 4O6NA 3T6BA 3QZCA 4E7ZA 5A6BA 1LE4A 2L81A 2A0BA 2BL2A 1OKKD 2EPNA 3L1MA 1NFOA 4YL3A 3K66A 1FMVA 2B0JA 2P61A 2LD6A 4PFOA 3TOMA 3CEXA 3O39A 4IAOA 1ZHTA 2J9BA 3N2ZB 4GQHA 1MQVA 3ZSUA 1CPRA 3ZVRA 3N24A 2NUTA 1RKEB 3SYNA 1ZHYA 1C17M 3MBGA 4JZAA 5KYWA 4EIYA 4XTKA 3U2MA 1LPEA 2IOQA 2P7VA 3ZG1A 1QSPA 3ECSA 2MHRA 2HSBA 2AU5A 2UUHA 3KYJA 4PFPA 2Q7RA 1KTMA 1TWGA 1YZCA 1ORJA 5K0IA 4JC7A 4FAPB 3EFOB 3Q7LA 4MTGA 1ORYA 4C3DA 2C04A 4F4BA 1H9GA 2Q9BA 2WL8A 1OKKA 1YJGA 3ITFA 4AX2A 1NU7D 2P0NA 3FXHA 5JS5A 1PV3A 2W9YA 5JLIA 2NPUA 4MTOA 2H7BA 2L6GA 1TR2A 3PDMP 1GGQA 4PACA 4BJ5A 2KGOA 2V3CC 2QTVA 1OCZC 2ZXOA 3C8GB 3PCVA 1M6TA 3O6XA 3UMHA 2WVQA 2A6EF 2B0HA 2L6FA 4E7SA 4R32A 5JUAA 3RYLA 2HKVA 5E3CA 1D0XA 1Q0KA 2HUJA 3G50A 3EGDA 1U0BB 1VYIA 2XLMA 1G4US 3LNRA 3ASNC 3IQ6A 2XM0A 3FHDA 4I3MA 2LQGA 2Y3BA 3K1IC 2ZXRA 1QPUA 2A0UA 2ICWG 4FWVA 4IAQA 2IXNA 1AUEA 5CI9A 3PHF2 2XXAB 5EHHA 1U6HA 1TFOB 5E3AA 1I4ZA 2LK4A 4XQ1A 1VLTA 1VMAA 3TD7A 4DRHB 4DRIB 3U5SA 3HNLA 3KYIA 1K04A 3GM1A 3U9MA 4MS2A 3GORA 2BC5A 2J7PD 2XSEA 5JSLA 3C62A 3TK0A 5DVWA 3S0XA 3NKEA 1MMAA 1WN0A 4KI2A 2YEVA 3U8PA 3AQBA 3HTKC 4NCQA 1O87A 4MW3A 2XLDA 4U5HA 3TJ5A 2Y3HA 3NMKA 4AL0A 1PD1A 4IB4A 1Q0GA 4MVQA 1Q0FA 4DBQA 1YARO 4IARA 1E84A 3O10A 5JP7A 2Y39A 1E86A 1O5HA 2GA0A 2VCAA 2ZXPA 4RBNA 5CIVA 1T6IA 2J0WA 3FOPA 4I1MA 2FAPB 3EZHA 4LACB 5BUOA 1FNTc 4WABA 4YWQA 3DI5A 2CYDA 5EGYA 4LDRA 1TQGA 2J7PA 1WATA 4P6IC 2CGEA 2Y69C 1QQ3A 1LS4A 1RCPA 5BQGA 2M64A 1JAFA 3VRCA 2L6HA 4IJJA 3QW1A 4UDVA 1WASA 3ABMC 4XLPF 1FMWA 3FAPB 4A4AA 3L0IA 1CGME 2PNOA 3EH2A 2GWWA 3KKBA 4JJFA 1OCOC 3B0VC 4O6MA 3QMKA 5KYYA 4YN0B 4YL1A 1Z23A 4IWBA 3G4XA 2EPMX 1AEPA 1HE1A 1IZMA 2XLHA 5DQTA 4O79A 3VYWA 3EG9B 2A69F 2YHSA 1S7ZA 5DLJA 2NUPA 4G7OF 2HV6A 1OR2A 2C03A 2KJGA 4HE8D 1LI5A 5F5HA 4PJNA 3FMSA 4LLEA 2DGJA 1OXKA 3AG3C 2XM4A 4K1OA 2MYSA 2Q00A 4NTFA 4XPWA 5A6AA 2VB6A 4CJOA 4XEFA 2OJED 3AGTA 4ULWA 2PFDA 5DS6A 5KYNA 2CW0F 4JTCB 2R7VA 1RKCA 4E0IA 3CAXA 2WZLA 3MYIA 2A6HF 3C8ZA 3JSEO 1SR2A 3EPVA 3KL4A 1LE2A 1LM3B 1HMOA 3MFNA 1FR0A 1OCCC 1HW2A 1XZPA 4U5EE 2W4MA 4G78A 5B3IA 2J9UA 4EHPA 1QVXA 1VOMA 5L0GA 2YLIA 2AWCA 3VM6A 1KNYA 1V55C 4ONSA 2DYRC 1VTMP 5KYUB 1LS1A 2XL6A 4CS9C 1JOGA 1K05A 4Q7CA 4Z9JA 1D1BA 3L8IA 1BR1A 2J46A 3NYLA 1BZ4A 4QI0A 3UMKA 2FGYA 2HSQA 3A11A 2YL7A 2YLDA 4RD9A 3SEOA 3TULA 3U2LA 4MVOA 2XS1A 2L7AA 3EHMA 5B3SC 3M4CA 4M63A 4Z9HA 3NKDA 1S05A 2YKZA 4N6HA 2CNWA 3CSKA 1BR2A 3UR3C 2OQMA 5AGFA 3H2UA 256BA 2NSGA 3NMIA 4CS8C 1W2WA 2X51A 3QVYA 2IM8A 5E2QA 2J0XA 3PMRA 3Q6NA 4GYTA 2HJMA 2OG2A 4WJ0A 3HLZA 5BQHA 2DI3A 3DZAA 3HKKA 2LFDA 3B0PA 3RW0A 3E9VA 3S28A 5A6KA 4BEMJ 1YVIA 3LJBA 1JRAA 2GAQA 2Z15A 2KYHA 3IQCA 1TKNA 2QE9A 3O55A 4AK9A 2OOCA 2R25A 1ZU5A 2HJ3A 1MMGA 3K7DA 3L8JA 3AJMA 2F22A 4CBEA 4NQFA 2NG1A 3H2VA 2R7OA 3RVYA 2I15A 3M1CB 1LI7A 1VLSA 3I5PA 4C3EA 2LIGA 2XLEA 3SXMA 4C7OB 2CCYA 1EQ1A 4K0DA 3DM5A 2R02A 3IHUA 3NYMA 1GS9A 3B29A 1A7VA 3GM2A 2AP3A 3GWNA 1YDIA 1ZW2A 4JW1A 4WGYA 2YL0A 4DVYP 2IXOA 4E18A 3ATPA 3S27A 3UGOA 3Q6MA 2XS8A 3LLIA 3F46A 2ZXWC 2J9VA 3R2PA 3LNMB 3H65A 2O9XA 4ER9A 2PX3A 4CX9A 1RMVA 3HJCA 3K1HA 1MMDA 4N6CA 4FX5A 3ABKC 3IQ5A 4JVSA 4W8KA 3UNGC 1G4WR 2A1DD 2I8BA 1A7DA 2D4UA 3F47A 2NSFA 2V26A 3OA1A 3RIPA 2L9JA 3TOLA 3Q7GA 3S84A 3U9JA 3US6A 2GDCA 2PP4A 2PX0A 3JT1A 2VC9A 3JZ0A 3KH2A 3OEOA 3M79A 2KSFA 1Y6DA 3W2WA 4W8PA 5DS4A 3TJ6A 1V54C 5HSWA 3GEIA 3GEHA 5F28E 2EPKX 3LS1A 4J7YA 1OR3A 2YL1A 3AG4C 2WB7A 1V74B 2QY9A 3LEVA 3S9OA 3T4RA 4CS8A 4XPYA 2R7WA 1LVKA 1RJ9B 4U5DE 2OEVA 3LAYA 2OCCC 4U5FE 1Q0DA 4K7BA 4BEJA 1IW7F 1U89A 4XPXA 3TQOA 1CGOA 4PJJA 1GQAA 1WTYA 3DAFA 4YJWA 5A69A 2TMVP 4QI2A 5KYYB 1JR8A 4B6IA 1D0ZA 4PR9A 1YA7O 4EBJA 2D5RB 3POVA 1EI7A 2RD9A 4ZLDA 1XWJA 4PJMA 5EK0A 1FFHA 2YL3A 2QLAA 3ASOC 2Y3GA 2XXAA 1TWHA 3DM9B 1C03A 2JD3A 4QDLA 1LIHA 1T9KA 1VB5A 4BJ6C 1MNDA 4AE4B 3MX3A 5COGA 4WGZA 3ZDLA 3JYYA 2XL8A 1I4YA 1T6UA 4XWJA 3LUTB 1NZEA 2DB4A 4MVSA 1E83A 1L7CA 3RF3A 1ST6A 5T1DB 5L3QA 2IYLD 2KC3A 2MWQA 2GFHA 4GEHA 4A2NB 1OW6A 4U5GA 1Z3IX 4D4XA 3K1IA 5COFA 2H7VC 3ZQVA 3BRJA 4HEAJ 3C18A 2LCHA 2Q9AA 5COMA 2EPOA 2RSEB 1G8XA 2HFIA 1NG1A 4PJLA 4OIOF 2VASA 5L0IA 3EGXA 1NSGB 1VYKA 3K33A 1FTSA 5JT4A 2YWAA 4MQ9F 5D91A 1Q0MA 1VK5A 4PK4A 1NBBA 2XL4A 3NRHA 5JVEA 2IBFA 3L34A 5KYXB 4DRJB 2ETSA 5D92A 4YT8A 4L6RA 2X0CA 3B0UX 4DVZA 2H8AA 2YLGA 1YLMA 5L0CA 2YQYA 4I1OB 3JTLO 3B9QA 3GEEA 1OXBA 4AL1A 1D1AA 2CNWD 1FAPB 4Q4ZF 3QVZA 2R05A 3U8VA 3JRTA 1TWCA 3I5QA 3V5ZA 1OQCA 2ASRA 2XLWA 3M15A 3RVZA 4O6YA 2J8WA 3WHNA 2YRFA 4FESA 3QW0A 3LS0A 3EG9A 2HV7A 3AOUA 4BJ5C 4CIPA 3IQTA 2G62A 1CGNA 1QLEC 1H6GA 4KC9A 1YYJA 3DD7A 4KNWA 4MVZA 2J45A 2NUTB 1Z5ZA 2EILC 1TFKB 1YYXA 2HMZA 3AG2C 3M4BA 1NFNA 3DKAA 1YA9A 4JTAB 4NC3A 5KYWB 1WOLA 1OCRC 5T3TA 1D0YA 1SF8A 3DAGA 3SXZA 3V5YA 4YL0A 3NDBB 1M2VA 3DWWA 3KMIA 3V5XA 4N06A 2OU6A 2Q4FA 4E17A 4NTBA 2R7RA 4OIPF 3EQLF 2R7XA 1T01A 1XZQA 4OD4A 2OEXA 3U3FA 1QKRA 4JTDB 2QNLA 4MVUA 1NLXA 4J7TA 1ZZPA 4MVRA 4DXWA 2HMQA 3S90A 2LSEA 2R7UA 4LLCA 4U9EA 3DE8A 2EPLX 1YAUO 1CPQA 4OD5A 3DJNB 3EGDB 5KYUA 4G7ZF 2G3KA 2EIMC 3RFYA 1A0BA 3J06A 1HY5A 3AGUA 1H7IA 1BDJB 1HE9A 4JJGA 5IY5C 2R7SA 4LDQA 2Y3DA 2XLOA 3K6BA 3CZ6A 3FDQA 1Z63A 1GM5A 1N1CA 1C02A 3LESA 1WWPA 2AVKA 1BR4A 3EH1A 5B1AC 4U5BE 3T6JA 3ZTMA 3X1OA 4BJ1A 4DOZA 1JPNA 4NY3A 4U5CE 2R9RB 3HNJA 4OIQF 1EA8A 3RQGA 1V4AA 3C8GD 1RKEA 3G4ZA 2LP4A 3VAYA 1J8MF 4ULVA 3ZIBA 4I44A 5DS5A 1M57C 3SZRA 1JPJA 5F5FA 4J30B 4CS9A 4CJGA 1T6QA 4RDAA 3RQEA 4G7HF 3W8HA 3ZQYA 1A41A 5A6JA 4BJ6A 2W4BA 3EFOA 4EUKB 1SMYF 2JX0A 2WVNA 4OINF 1G5ZA 3UGPA 1R4TA 2ZD9A 3GODA 1HMDA 3BEHA 3WG7C 3ZTZA 5FCLA 1MMNA 4YK5A 1ZW3A 3C63A 4JCZA 3MYFA 2DYSC 2R7QA 4EBKA 2YZSA 4HFFB 3C8GA 2Q3TA 4JURI 3VF0A 5L0DA 4CDVA 5TJ5E 4JIOA 4G0HA 4LDKA 3LEOA 4C7OA 5L0JA 1R5ID 2HS5A 1WGWA 1H9TA 1EKYA 3LLKA 2HZ8A 3N0TA 3SXKA 3SP1A 1RXQA 4MVMA 3ZC4A 4DJ9A 2R7TA 3W2VA 3DXJF 1KU2A 2UUIA 2WZGA 4JKVA 2W45A 3AQCA 4BG0A 3S29A 2KNHA 3CQZA 4X0RA
chains in the Genus database with same CATH topology
3PCVA 2PNOA 4YL3A 4YL0A 4NTAA 3DWWA 4YK5A 4YL1A 2H8AA 4JCZA 3B29A 4AL0A 4NTBA 4J7YA 4AL1A 5BQHA 4JRZA 3HKKA 2UUHA 3LEOA 2Q7RA 5K0IA 4JC7A 4BPMA 4J7TA 4NTFA 4WABA 5BQIA 5BQGA 2UUIA 5HV9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PCV A;  2PNO A;  4YL3 A;  4YL0 A;  4NTA A;  3DWW A;  4YK5 A;  4YL1 A;  2H8A A;  4JCZ A;  3B29 A;  4AL0 A;  4NTB A;  4J7Y A;  4AL1 A;  5BQH A;  4JRZ A;  3HKK A;  2UUH A;  3LEO A;  2Q7R A;  5K0I A;  4JC7 A;  4BPM A;  4J7T A;  4NTF A;  4WAB A;  5BQI A;  5BQG A;  2UUI A;  5HV9 A; 
#chains in the Genus database with same CATH topology
 4P9F A;  2R03 A;  2WZF A;  4YT5 A;  1PD0 A;  3JSZ A;  4IGG A;  2ZPA A;  4XEV A;  4BJT A;  2NUP B;  1APC A;  2VCB A;  2XRH A;  1ORS C;  2YVK A;  3AG1 C;  4IRU A;  5B1B C;  4NTA A;  3WAQ A;  2IXM A;  5E33 A;  5AC4 A;  1F1M A;  2VCC A;  4MTF A;  1ZHW A;  3HNK A;  4P9T A;  1AVO B;  3JCU Q;  5T3W A;  1TWA A;  3KPH A;  4KBL A;  1HW1 A;  3A9C A;  1ZYR F;  3I4U A;  4CSA C;  1E2X A;  5L0F A;  2XLV A;  1T5O A;  3EGX B;  4D4N A;  1I5N A;  4JEB A;  3V7O A;  1QZX A;  2OJQ A;  3T6G B;  1L3P A;  4N4W A;  3W8I A;  4LER A;  2AWY A;  1A7E A;  3JRM O;  1DOW A;  1M2O A;  1OW7 A;  2P6V A;  4OIR F;  5HV9 A;  1RJ9 A;  2IXP A;  1ZU4 A;  2KK1 A;  3GM3 A;  4O7G A;  3SXY A;  4CDY A;  4CIH A;  3GWL A;  3SNH A;  3FVY A;  3QTH A;  3DJU B;  3UMI A;  3DMD A;  2E87 A;  3B71 A;  1SZI A;  3RQF A;  3NYJ A;  1Z6A A;  4YT2 A;  4HFK B;  4MND A;  4C3B A;  5L3V A;  3W4Y A;  1B68 A;  2PBE A;  4EKW A;  1LKX A;  2PF4 E;  3GAN A;  1D1C A;  4CS7 A;  3FOO A;  4ZLC A;  2M4E A;  4J32 B;  5AC5 A;  3MLG A;  2VH3 A;  3C7J A;  4JRZ A;  3DE9 A;  4Q5S F;  4JE9 A;  1MNE A;  3ZWI A;  2WVO A;  3NG1 A;  2J9W A;  5FZT A;  4AE4 A;  1OW8 A;  4JCH A;  4BPM A;  3X2Q C;  1UFB A;  4Z9I A;  1M2V B;  3FAJ A;  2FFH A;  5BQI A;  2A68 F;  4XEK A;  3ABL C;  3WOD F;  1NU9 C;  1J8Y F;  4EWC A;  2KW3 C;  3JYH A;  4U9D A;  4CDA A;  5A6B D;  1ZHZ A;  2EIN C;  3IPM O;  1PCX A;  3EJN A;  2G3V A;  2H7O A;  4MW8 A;  2CDQ A;  2QUP A;  2LFF A;  2BE5 F;  4ANJ A;  4YT4 A;  4KNV A;  4H54 A;  5CI8 A;  5GPG B;  4DBR A;  5JRA A;  1E85 A;  4XLN F;  3OWT A;  2KQ9 A;  4EBB A;  1M56 C;  2EIJ C;  2EIK C;  5L0H A;  5KYX A;  1YZA A;  4CSA A;  1O3U A;  1UG7 A;  1Y4C A;  2P1A A;  3IEE A;  3T9O A;  1K40 A;  3EHN A;  3U0C A;  1FFT C;  5DQZ A;  1Z7Q c;  1BBH A;  3U3B A;  1DOV A;  1ZHX A;  1JMW A;  3HNI A;  4H4K C;  3R7C A;  3RH3 A;  4E0H A;  2JPU A;  1SYQ A;  1ZVZ A;  2OKU A;  3E70 C;  4JEA A;  3NMJ A;  3RKO F;  3EZI A;  2Q9C A;  4O6N A;  3T6B A;  3QZC A;  4E7Z A;  5A6B A;  1LE4 A;  2L81 A;  2A0B A;  2BL2 A;  1OKK D;  2EPN A;  3L1M A;  1NFO A;  4YL3 A;  3K66 A;  1FMV A;  2B0J A;  2P61 A;  2LD6 A;  4PFO A;  3TOM A;  3CEX A;  3O39 A;  4IAO A;  1ZHT A;  2J9B A;  3N2Z B;  4GQH A;  1MQV A;  3ZSU A;  1CPR A;  3ZVR A;  3N24 A;  2NUT A;  1RKE B;  3SYN A;  1ZHY A;  1C17 M;  3MBG A;  4JZA A;  5KYW A;  4EIY A;  4XTK A;  3U2M A;  1LPE A;  2IOQ A;  2P7V A;  3ZG1 A;  1QSP A;  3ECS A;  2MHR A;  2HSB A;  2AU5 A;  2UUH A;  3KYJ A;  4PFP A;  2Q7R A;  1KTM A;  1TWG A;  1YZC A;  1ORJ A;  5K0I A;  4JC7 A;  4FAP B;  3EFO B;  3Q7L A;  4MTG A;  1ORY A;  4C3D A;  2C04 A;  4F4B A;  1H9G A;  2Q9B A;  2WL8 A;  1OKK A;  1YJG A;  3ITF A;  4AX2 A;  1NU7 D;  2P0N A;  3FXH A;  5JS5 A;  1PV3 A;  2W9Y A;  5JLI A;  2NPU A;  4MTO A;  2H7B A;  2L6G A;  1TR2 A;  3PDM P;  1GGQ A;  4PAC A;  4BJ5 A;  2KGO A;  2V3C C;  2QTV A;  1OCZ C;  2ZXO A;  3C8G B;  3PCV A;  1M6T A;  3O6X A;  3UMH A;  2WVQ A;  2A6E F;  2B0H A;  2L6F A;  4E7S A;  4R32 A;  5JUA A;  3RYL A;  2HKV A;  5E3C A;  1D0X A;  1Q0K A;  2HUJ A;  3G50 A;  3EGD A;  1U0B B;  1VYI A;  2XLM A;  1G4U S;  3LNR A;  3ASN C;  3IQ6 A;  2XM0 A;  3FHD A;  4I3M A;  2LQG A;  2Y3B A;  3K1I C;  2ZXR A;  1QPU A;  2A0U A;  2ICW G;  4FWV A;  4IAQ A;  2IXN A;  1AUE A;  5CI9 A;  3PHF 2;  2XXA B;  5EHH A;  1U6H A;  1TFO B;  5E3A A;  1I4Z A;  2LK4 A;  4XQ1 A;  1VLT A;  1VMA A;  3TD7 A;  4DRH B;  4DRI B;  3U5S A;  3HNL A;  3KYI A;  1K04 A;  3GM1 A;  3U9M A;  4MS2 A;  3GOR A;  2BC5 A;  2J7P D;  2XSE A;  5JSL A;  3C62 A;  3TK0 A;  5DVW A;  3S0X A;  3NKE A;  1MMA A;  1WN0 A;  4KI2 A;  2YEV A;  3U8P A;  3AQB A;  3HTK C;  4NCQ A;  1O87 A;  4MW3 A;  2XLD A;  4U5H A;  3TJ5 A;  2Y3H A;  3NMK A;  4AL0 A;  1PD1 A;  4IB4 A;  1Q0G A;  4MVQ A;  1Q0F A;  4DBQ A;  1YAR O;  4IAR A;  1E84 A;  3O10 A;  5JP7 A;  2Y39 A;  1E86 A;  1O5H A;  2GA0 A;  2VCA A;  2ZXP A;  4RBN A;  5CIV A;  1T6I A;  2J0W A;  3FOP A;  4I1M A;  2FAP B;  3EZH A;  4LAC B;  5BUO A;  1FNT c;  4WAB A;  4YWQ A;  3DI5 A;  2CYD A;  5EGY A;  4LDR A;  1TQG A;  2J7P A;  1WAT A;  4P6I C;  2CGE A;  2Y69 C;  1QQ3 A;  1LS4 A;  1RCP A;  5BQG A;  2M64 A;  1JAF A;  3VRC A;  2L6H A;  4IJJ A;  3QW1 A;  4UDV A;  1WAS A;  3ABM C;  4XLP F;  1FMW A;  3FAP B;  4A4A A;  3L0I A;  1CGM E;  2PNO A;  3EH2 A;  2GWW A;  3KKB A;  4JJF A;  1OCO C;  3B0V C;  4O6M A;  3QMK A;  5KYY A;  4YN0 B;  4YL1 A;  1Z23 A;  4IWB A;  3G4X A;  2EPM X;  1AEP A;  1HE1 A;  1IZM A;  2XLH A;  5DQT A;  4O79 A;  3VYW A;  3EG9 B;  2A69 F;  2YHS A;  1S7Z A;  5DLJ A;  2NUP A;  4G7O F;  2HV6 A;  1OR2 A;  2C03 A;  2KJG A;  4HE8 D;  1LI5 A;  5F5H A;  4PJN A;  3FMS A;  4LLE A;  2DGJ A;  1OXK A;  3AG3 C;  2XM4 A;  4K1O A;  2MYS A;  2Q00 A;  4NTF A;  4XPW A;  5A6A A;  2VB6 A;  4CJO A;  4XEF A;  2OJE D;  3AGT A;  4ULW A;  2PFD A;  5DS6 A;  5KYN A;  2CW0 F;  4JTC B;  2R7V A;  1RKC A;  4E0I A;  3CAX A;  2WZL A;  3MYI A;  2A6H F;  3C8Z A;  3JSE O;  1SR2 A;  3EPV A;  3KL4 A;  1LE2 A;  1LM3 B;  1HMO A;  3MFN A;  1FR0 A;  1OCC C;  1HW2 A;  1XZP A;  4U5E E;  2W4M A;  4G78 A;  5B3I A;  2J9U A;  4EHP A;  1QVX A;  1VOM A;  5L0G A;  2YLI A;  2AWC A;  3VM6 A;  1KNY A;  1V55 C;  4ONS A;  2DYR C;  1VTM P;  5KYU B;  1LS1 A;  2XL6 A;  4CS9 C;  1JOG A;  1K05 A;  4Q7C A;  4Z9J A;  1D1B A;  3L8I A;  1BR1 A;  2J46 A;  3NYL A;  1BZ4 A;  4QI0 A;  3UMK A;  2FGY A;  2HSQ A;  3A11 A;  2YL7 A;  2YLD A;  4RD9 A;  3SEO A;  3TUL A;  3U2L A;  4MVO A;  2XS1 A;  2L7A A;  3EHM A;  5B3S C;  3M4C A;  4M63 A;  4Z9H A;  3NKD A;  1S05 A;  2YKZ A;  4N6H A;  2CNW A;  3CSK A;  1BR2 A;  3UR3 C;  2OQM A;  5AGF A;  3H2U A;  256B A;  2NSG A;  3NMI A;  4CS8 C;  1W2W A;  2X51 A;  3QVY A;  2IM8 A;  5E2Q A;  2J0X A;  3PMR A;  3Q6N A;  4GYT A;  2HJM A;  2OG2 A;  4WJ0 A;  3HLZ A;  5BQH A;  2DI3 A;  3DZA A;  3HKK A;  2LFD A;  3B0P A;  3RW0 A;  3E9V A;  3S28 A;  5A6K A;  4BEM J;  1YVI A;  3LJB A;  1JRA A;  2GAQ A;  2Z15 A;  2KYH A;  3IQC A;  1TKN A;  2QE9 A;  3O55 A;  4AK9 A;  2OOC A;  2R25 A;  1ZU5 A;  2HJ3 A;  1MMG A;  3K7D A;  3L8J A;  3AJM A;  2F22 A;  4CBE A;  4NQF A;  2NG1 A;  3H2V A;  2R7O A;  3RVY A;  2I15 A;  3M1C B;  1LI7 A;  1VLS A;  3I5P A;  4C3E A;  2LIG A;  2XLE A;  3SXM A;  4C7O B;  2CCY A;  1EQ1 A;  4K0D A;  3DM5 A;  2R02 A;  3IHU A;  3NYM A;  1GS9 A;  3B29 A;  1A7V A;  3GM2 A;  2AP3 A;  3GWN A;  1YDI A;  1ZW2 A;  4JW1 A;  4WGY A;  2YL0 A;  4DVY P;  2IXO A;  4E18 A;  3ATP A;  3S27 A;  3UGO A;  3Q6M A;  2XS8 A;  3LLI A;  3F46 A;  2ZXW C;  2J9V A;  3R2P A;  3LNM B;  3H65 A;  2O9X A;  4ER9 A;  2PX3 A;  4CX9 A;  1RMV A;  3HJC A;  3K1H A;  1MMD A;  4N6C A;  4FX5 A;  3ABK C;  3IQ5 A;  4JVS A;  4W8K A;  3UNG C;  1G4W R;  2A1D D;  2I8B A;  1A7D A;  2D4U A;  3F47 A;  2NSF A;  2V26 A;  3OA1 A;  3RIP A;  2L9J A;  3TOL A;  3Q7G A;  3S84 A;  3U9J A;  3US6 A;  2GDC A;  2PP4 A;  2PX0 A;  3JT1 A;  2VC9 A;  3JZ0 A;  3KH2 A;  3OEO A;  3M79 A;  2KSF A;  1Y6D A;  3W2W A;  4W8P A;  5DS4 A;  3TJ6 A;  1V54 C;  5HSW A;  3GEI A;  3GEH A;  5F28 E;  2EPK X;  3LS1 A;  4J7Y A;  1OR3 A;  2YL1 A;  3AG4 C;  2WB7 A;  1V74 B;  2QY9 A;  3LEV A;  3S9O A;  3T4R A;  4CS8 A;  4XPY A;  2R7W A;  1LVK A;  1RJ9 B;  4U5D E;  2OEV A;  3LAY A;  2OCC C;  4U5F E;  1Q0D A;  4K7B A;  4BEJ A;  1IW7 F;  1U89 A;  4XPX A;  3TQO A;  1CGO A;  4PJJ A;  1GQA A;  1WTY A;  3DAF A;  4YJW A;  5A69 A;  2TMV P;  4QI2 A;  5KYY B;  1JR8 A;  4B6I A;  1D0Z A;  4PR9 A;  1YA7 O;  4EBJ A;  2D5R B;  3POV A;  1EI7 A;  2RD9 A;  4ZLD A;  1XWJ A;  4PJM A;  5EK0 A;  1FFH A;  2YL3 A;  2QLA A;  3ASO C;  2Y3G A;  2XXA A;  1TWH A;  3DM9 B;  1C03 A;  2JD3 A;  4QDL A;  1LIH A;  1T9K A;  1VB5 A;  4BJ6 C;  1MND A;  4AE4 B;  3MX3 A;  5COG A;  4WGZ A;  3ZDL A;  3JYY A;  2XL8 A;  1I4Y A;  1T6U A;  4XWJ A;  3LUT B;  1NZE A;  2DB4 A;  4MVS A;  1E83 A;  1L7C A;  3RF3 A;  1ST6 A;  5T1D B;  5L3Q A;  2IYL D;  2KC3 A;  2MWQ A;  2GFH A;  4GEH A;  4A2N B;  1OW6 A;  4U5G A;  1Z3I X;  4D4X A;  3K1I A;  5COF A;  2H7V C;  3ZQV A;  3BRJ A;  4HEA J;  3C18 A;  2LCH A;  2Q9A A;  5COM A;  2EPO A;  2RSE B;  1G8X A;  2HFI A;  1NG1 A;  4PJL A;  4OIO F;  2VAS A;  5L0I A;  3EGX A;  1NSG B;  1VYK A;  3K33 A;  1FTS A;  5JT4 A;  2YWA A;  4MQ9 F;  5D91 A;  1Q0M A;  1VK5 A;  4PK4 A;  1NBB A;  2XL4 A;  3NRH A;  5JVE A;  2IBF A;  3L34 A;  5KYX B;  4DRJ B;  2ETS A;  5D92 A;  4YT8 A;  4L6R A;  2X0C A;  3B0U X;  4DVZ A;  2H8A A;  2YLG A;  1YLM A;  5L0C A;  2YQY A;  4I1O B;  3JTL O;  3B9Q A;  3GEE A;  1OXB A;  4AL1 A;  1D1A A;  2CNW D;  1FAP B;  4Q4Z F;  3QVZ A;  2R05 A;  3U8V A;  3JRT A;  1TWC A;  3I5Q A;  3V5Z A;  1OQC A;  2ASR A;  2XLW A;  3M15 A;  3RVZ A;  4O6Y A;  2J8W A;  3WHN A;  2YRF A;  4FES A;  3QW0 A;  3LS0 A;  3EG9 A;  2HV7 A;  3AOU A;  4BJ5 C;  4CIP A;  3IQT A;  2G62 A;  1CGN A;  1QLE C;  1H6G A;  4KC9 A;  1YYJ A;  3DD7 A;  4KNW A;  4MVZ A;  2J45 A;  2NUT B;  1Z5Z A;  2EIL C;  1TFK B;  1YYX A;  2HMZ A;  3AG2 C;  3M4B A;  1NFN A;  3DKA A;  1YA9 A;  4JTA B;  4NC3 A;  5KYW B;  1WOL A;  1OCR C;  5T3T A;  1D0Y A;  1SF8 A;  3DAG A;  3SXZ A;  3V5Y A;  4YL0 A;  3NDB B;  1M2V A;  3DWW A;  3KMI A;  3V5X A;  4N06 A;  2OU6 A;  2Q4F A;  4E17 A;  4NTB A;  2R7R A;  4OIP F;  3EQL F;  2R7X A;  1T01 A;  1XZQ A;  4OD4 A;  2OEX A;  3U3F A;  1QKR A;  4JTD B;  2QNL A;  4MVU A;  1NLX A;  4J7T A;  1ZZP A;  4MVR A;  4DXW A;  2HMQ A;  3S90 A;  2LSE A;  2R7U A;  4LLC A;  4U9E A;  3DE8 A;  2EPL X;  1YAU O;  1CPQ A;  4OD5 A;  3DJN B;  3EGD B;  5KYU A;  4G7Z F;  2G3K A;  2EIM C;  3RFY A;  1A0B A;  3J06 A;  1HY5 A;  3AGU A;  1H7I A;  1BDJ B;  1HE9 A;  4JJG A;  5IY5 C;  2R7S A;  4LDQ A;  2Y3D A;  2XLO A;  3K6B A;  3CZ6 A;  3FDQ A;  1Z63 A;  1GM5 A;  1N1C A;  1C02 A;  3LES A;  1WWP A;  2AVK A;  1BR4 A;  3EH1 A;  5B1A C;  4U5B E;  3T6J A;  3ZTM A;  3X1O A;  4BJ1 A;  4DOZ A;  1JPN A;  4NY3 A;  4U5C E;  2R9R B;  3HNJ A;  4OIQ F;  1EA8 A;  3RQG A;  1V4A A;  3C8G D;  1RKE A;  3G4Z A;  2LP4 A;  3VAY A;  1J8M F;  4ULV A;  3ZIB A;  4I44 A;  5DS5 A;  1M57 C;  3SZR A;  1JPJ A;  5F5F A;  4J30 B;  4CS9 A;  4CJG A;  1T6Q A;  4RDA A;  3RQE A;  4G7H F;  3W8H A;  3ZQY A;  1A41 A;  5A6J A;  4BJ6 A;  2W4B A;  3EFO A;  4EUK B;  1SMY F;  2JX0 A;  2WVN A;  4OIN F;  1G5Z A;  3UGP A;  1R4T A;  2ZD9 A;  3GOD A;  1HMD A;  3BEH A;  3WG7 C;  3ZTZ A;  5FCL A;  1MMN A;  4YK5 A;  1ZW3 A;  3C63 A;  4JCZ A;  3MYF A;  2DYS C;  2R7Q A;  4EBK A;  2YZS A;  4HFF B;  3C8G A;  2Q3T A;  4JUR I;  3VF0 A;  5L0D A;  4CDV A;  5TJ5 E;  4JIO A;  4G0H A;  4LDK A;  3LEO A;  4C7O A;  5L0J A;  1R5I D;  2HS5 A;  1WGW A;  1H9T A;  1EKY A;  3LLK A;  2HZ8 A;  3N0T A;  3SXK A;  3SP1 A;  1RXQ A;  4MVM A;  3ZC4 A;  4DJ9 A;  2R7T A;  3W2V A;  3DXJ F;  1KU2 A;  2UUI A;  2WZG A;  4JKV A;  2W45 A;  3AQC A;  4BG0 A;  3S29 A;  2KNH A;  3CQZ A;  4X0R A; 
#chains in the Genus database with same CATH homology
 3PCV A;  2PNO A;  4YL3 A;  4YL0 A;  4NTA A;  3DWW A;  4YK5 A;  4YL1 A;  2H8A A;  4JCZ A;  3B29 A;  4AL0 A;  4NTB A;  4J7Y A;  4AL1 A;  5BQH A;  4JRZ A;  3HKK A;  2UUH A;  3LEO A;  2Q7R A;  5K0I A;  4JC7 A;  4BPM A;  4J7T A;  4NTF A;  4WAB A;  5BQI A;  5BQG A;  2UUI A;  5HV9 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...