4JRZA

Human ltc4 synthase in complex with product analogs - implications for enzyme catalysis
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
155
structure length
155
Chain Sequence
MHHHHHHKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALFLLVALAALGLLAHFLPAALRAALLGRLRTLLPW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords Leukotriene C4 synthase
total genus 60
structure length 155
sequence length 155
ec nomenclature ec 4.4.1.20: Leukotriene-C(4) synthase.
pdb deposition date 2013-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01124 MAPEG MAPEG family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.550 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Membrane associated eicosanoid/glutathione metabolism-like domain 4jrzA00
4WABA 2H8AA 4JC7A 4AL0A 2PNOA 4BPMA 4J7TA 3PCVA 2UUHA 5BQIA 4AL1A 3B29A 2UUIA 3LEOA 5BQHA 5BQGA 4YK5A 3HKKA 4NTFA 5K0IA 2Q7RA 3DWWA 4NTBA 4YL3A 4JRZA 4JCZA 4YL1A 4YL0A 5HV9A 4J7YA 4NTAA
chains in the Genus database with same CATH superfamily
2DI3A 4CJGA 2VASA 5L0HA 4FWVA 2R7RA 3SP1A 1LPEA 2KYHA 4RBNA 1I5NA 1OW8A 2ZXWC 2J9WA 3K7DA 3RVYA 4JVSA 3WODF 2KSFA 3GORA 2LSEA 1Q0DA 1CPQA 3S0XA 1ZW2A 3DM5A 2HFIA 4PJJA 1RMVA 2R7OA 4N6CA 3V7OA 2YL7A 4CDAA 5L0IA 3FOOA 4H54A 4MVMA 1LIHA 2LCHA 1M56C 1Z6AA 1IZMA 1S05A 2DB4A 3LAYA 2D4UA 4MTGA 3I5PA 2KQ9A 4U5HA 1OKKD 1R5ID 1JPNA 4RD9A 1TFKB 1TWAA 2IYLD 3IQTA 3TJ6A 3UGPA 2ICWG 4YL0A 3ZIBA 4ZLDA 3ABLC 1OW6A 3NYLA 3QVYA 2IXMA 3QTHA 2XLEA 1OQCA 3NG1A 5CI9A 1I4ZA 3LS1A 1LI7A 2Q00A 1LS4A 3U2LA 3EGDB 5GPGB 2WVQA 1W2WA 2KC3A 3MFNA 4IAQA 5B1BC 1OW7A 1QQ3A 4XLPF 2PX0A 4KNVA 4YT5A 5DQTA 3EGDA 4JEAA 1YJGA 3JSEO 4H4KC 4LDKA 3B0UX 3WG7C 3T6BA 3N0TA 1H9GA 1UG7A 2CCYA 1D1CA 3ZC4A 3SXZA 3C8GB 4U5BE 3MYFA 2CYDA 1SF8A 3LNRA 1TR2A 4DJ9A 4NY3A 2FFHA 2GWWA 1D0YA 3MLGA 1TKNA 1DOVA 2RSEB 5T3TA 4YT8A 1Y6DA 3C62A 3KPHA 4NTAA 1TQGA 1YYJA 3JRTA 1LI5A 2IOQA 3DXJF 2J9UA 1A7DA 1SYQA 2OEXA 3T6JA 1QVXA 2PP4A 4CBEA 1TWCA 2R02A 3PHF2 1KU2A 1Z7Qc 2P0NA 2NUPA 3K6BA 2L7AA 1FFHA 4BPMA 3SXYA 4IB4A 2AWYA 1Z3IX 4W8PA 3RH3A 4CIPA 3S29A 1F1MA 4HE8D 5BQIA 3TOMA 2CGEA 3V5XA 3CEXA 4IJJA 5KYUB 1WTYA 5COFA 5AC4A 3WAQA 1L3PA 2C04A 2J9VA 2YZSA 3DMDA 3EPVA 2QUPA 4WJ0A 4YK5A 2EPNA 4XTKA 3DZAA 3DAFA 5KYUA 4CS9A 4LDRA 3L1MA 4DRIB 1LVKA 2WB7A 5A6KA 4BEMJ 1M2VB 2XRHA 3Q7GA 1YVIA 4DOZA 3GEHA 2A68F 2Q3TA 2XLDA 3X1OA 4JW1A 5E2QA 3UR3C 3DE8A 2RD9A 2XL6A 4EKWA 3J06A 1FMVA 1M2VA 1A7VA 2YEVA 2XLOA 3EHNA 2QY9A 3FMSA 3RKOF 3KH2A 2D5RB 4OIOF 2I8BA 2GA0A 3TULA 2JPUA 1FAPB 2EPLX 1J8YF 1VYIA 3PCVA 3FHDA 1PV3A 3UGOA 3AG1C 3AG2C 2OEVA 2MHRA 1VLSA 2QNLA 3QW1A 4E17A 5L0GA 3RVZA 2P1AA 2XLWA 3T6GB 4EBKA 3I4UA 2HSBA 3NKEA 4MW8A 5L0JA 2DYRC 4A2NB 3VRCA 3HNIA 4Q4ZF 2XL8A 4C3BA 5K0IA 3BEHA 3SNHA 4CS7A 1E85A 2NUTB 1T5OA 1UFBA 3T9OA 3OA1A 4U5CE 2YQYA 3K1IA 3JCUQ 4E0IA 3DJNB 1NFNA 1JAFA 1RKEB 2GFHA 3RIPA 3SYNA 4YN0B 2M64A 4CS9C 4JURI 4BG0A 1OCOC 3EZIA 2QTVA 3NYJA 4PFOA 2XS8A 4AL0A 3W2VA 2E87A 3EFOB 1PD1A 1RKEA 3FXHA 4DBRA 1TFOB 2A0BA 1M57C 4Z9IA 4U9EA 2PNOA 4JCHA 2HS5A 3C63A 4GQHA 4XPWA 3EFOA 3TD7A 1BZ4A 3DI5A 4DBQA 4FX5A 1G4WR 4GEHA 3TJ5A 1ORSC 3LUTB 5JRAA 4JZAA 3PDMP 2W4BA 4JIOA 1WATA 2R9RB 1I4YA 3HNJA 4MS2A 1BR4A 1M2OA 2A6HF 2LFDA 2R05A 1YDIA 2L81A 3K66A 3OWTA 5CI8A 1E86A 1IW7F 4G78A 1YLMA 3W4YA 3N2ZB 3KKBA 4EBJA 1MMNA 4KC9A 5COMA 1ZHYA 1N1CA 2TMVP 2OCCC 3RW0A 3W2WA 2Q9BA 3ECSA 3W8IA 5A6JA 4OIPF 1YYXA 3FDQA 3O10A 1LS1A 1KTMA 2ZXPA 1OXKA 4CSAC 4G7HF 5F5FA 3K1IC 2IXPA 4YT4A 2Z15A 3RF3A 3UNGC 1LKXA 1FFTC 2YHSA 1A41A 3LJBA 1NZEA 3LS0A 4PJMA 4XEVA 4L6RA 5T3WA 2BL2A 2IM8A 5L0FA 4XWJA 2UUHA 1U6HA 5B3IA 4BEJA 4IAOA 4J32B 1U89A 4D4NA 2J7PA 3SXKA 4BJ5C 2YVKA 3VYWA 3NMIA 4MVZA 4XPXA 5JSLA 2EIKC 3PMRA 2XL4A 1JR8A 3U5SA 2O9XA 3GEEA 3GANA 2J0XA 2H7VC 3NMJA 1M6TA 2AVKA 3C7JA 4OD5A 5E3CA 3U3FA 3RYLA 2XM4A 3VM6A 2EIJC 2WZFA 4O7GA 1APCA 2HV6A 4EIYA 1ZHTA 4O6MA 1CPRA 3C8GD 2HJ3A 1O3UA 2BC5A 3HNLA 4NC3A 3AG4C 3IQ5A 1QLEC 4A4AA 1TWGA 3CQZA 3IQCA 3LLKA 4MTOA 3LEOA 2R7SA 4JE9A 5BQHA 2R7TA 3KL4A 2XM0A 3L0IA 3RQFA 5A6AA 2L6HA 1BR1A 3AJMA 2H7BA 2ZD9A 3GM3A 4I44A 4ULVA 3A9CA 2R03A 4YJWA 4Z9HA 5BQGA 3V5ZA 4D4XA 5AGFA 2IXOA 4W8KA 3U2MA 3U9MA 1U0BB 1T6UA 1EKYA 1GQAA 3CZ6A 3UMIA 4DVZA 4MVUA 3B29A 5HV9A 2OU6A 2ZXOA 1VOMA 4WABA 1H6GA 3EHMA 2NUPB 1WWPA 1Z5ZA 3DJUB 1YARO 3O55A 2KJGA 2Q9AA 1WGWA 3IHUA 4U5FE 1FNTc 3KMIA 5AC5A 3QMKA 2XLHA 2P6VA 3JRMO 3IEEA 4IGGA 3EJNA 4NCQA 1K05A 3IQ6A 1PD0A 2PFDA 3DD7A 3SXMA 2DGJA 1BDJB 2OQMA 4EUKB 2UUIA 4EWCA 4JTDB 1JRAA 2Y3BA 4N6HA 1OKKA 4N06A 1VK5A 4WGZA 3SEOA 2L6GA 4HFFB 2R25A 3TOLA 3TK0A 5KYYB 2WVNA 3BRJA 3JZ0A 2R7QA 4O6NA 3S28A 3GWLA 3QVZA 3EH1A 5JUAA 3JYYA 4JCZA 4P9TA 5T1DB 2PF4E 2AWCA 4K1OA 4O6YA 3U8VA 3L8IA 2AU5A 3VF0A 5KYYA 1RKCA 3GEIA 5D91A 4U5DE 1ZHWA 1QSPA 1MNEA 3MYIA 4MQ9F 3F47A 3ZQYA 2V26A 3UMKA 4G0HA 2W4MA 4OIQF 5BUOA 3C8ZA 4MNDA 1V54C 1H9TA 1MMAA 4FESA 1S7ZA 2LP4A 3NRHA 2PBEA 2ZPAA 3ABMC 3AQCA 3M15A 1T9KA 3DM9B 1YA7O 3FAJA 2XS1A 1AEPA 2G62A 3GM2A 2NPUA 4I1OB 4OIRF 2WZLA 1FR0A 2Q7RA 1HW1A 2YRFA 1OXBA 4XQ1A 3U9JA 2V3CC 1K04A 1R4TA 2AP3A 2NSGA 3O39A 2A1DD 2CNWA 1HW2A 5HSWA 2YL3A 4AK9A 1A7EA 4JC7A 1SMYF 4EBBA 1YZAA 4O79A 4ULWA 1ORYA 2I15A 3ZDLA 2HMZA 4PFPA 2Y39A 2R7WA 3H65A 2P61A 1KNYA 4QI2A 5DS5A 1ZHXA 4J7TA 4MVQA 2VB6A 1MQVA 1JMWA 4RDAA 1MMDA 4WGYA 3NDBB 2LIGA 3ABKC 2XLVA 5EHHA 2QE9A 2EIMC 3LESA 4ZLCA 2R7VA 2KGOA 5JP7A 1VB5A 3EH2A 2EPKX 3HKKA 2CW0F 3OEOA 1OR2A 4P9FA 1EA8A 2J7PD 3UMHA 2JX0A 1OCCC 1HY5A 1VYKA 2G3KA 2Y69C 4F4BA 1RXQA 4FAPB 1A0BA 1NBBA 3Q6NA 1ZHZA 3FOPA 4JRZA 1K40A 2HSQA 5JS5A 1O5HA 2A6EF 5COGA 1CGOA 1QKRA 1CGME 4IWBA 2H8AA 4YWQA 3E9VA 1ZVZA 2M4EA 2DYSC 2Y3HA 5B1AC 4CS8A 1V55C 3C18A 2NG1A 3L8JA 3K33A 1VLTA 4HFKB 1YAUO 4K7BA 3V5YA 3S84A 3FAPB 5B3SC 2VCCA 4LERA 4LLEA 1G8XA 4HEAJ 5FZTA 5A6BA 3JSZA 3HTKC 2MWQA 1HMOA 3X2QC 5E33A 3ZWIA 1TWHA 5KYXA 1XZQA 1V74B 2A69F 4IARA 4N4WA 5JLIA 1OCZC 2IXNA 2W45A 1NU7D 1L7CA 3DWWA 3LEVA 4C3EA 1JPJA 2YLIA 4J7YA 1Q0KA 2Q4FA 3EG9A 256BA 3NYMA 4Z9JA 5L3VA 4E7SA 5L3QA 3G4XA 3US6A 1J8MF 1YZCA 1C17M 3AGTA 1OR3A 1GGQA 3ATPA 2OJED 5KYNA 2OG2A 4KNWA 3EGXB 1AUEA 3U8PA 2B0HA 2WVOA 2OKUA 3F46A 5F5HA 1NFOA 2YKZA 3EGXA 3LLIA 3MBGA 1PCXA 4CS8C 4ONSA 3R2PA 4XEKA 3RQEA 2MYSA 1FTSA 4JKVA 4ER9A 4B6IA 3DE9A 1T01A 5DVWA 3ZTMA 2KK1A 2XLMA 4CJOA 4PK4A 1D1AA 3B71A 3SZRA 3JTLO 2LK4A 1VMAA 5L0DA 2QLAA 1Q0GA 1AVOB 2IBFA 4GYTA 4NQFA 3CAXA 4CX9A 1ZZPA 1WOLA 1EI7A 5KYWB 4C7OB 2ZXRA 4KBLA 3ASNC 1GS9A 4KI2A 3Q7LA 2KW3C 3HNKA 1OCRC 3IPMO 2J46A 4BJ6A 2OJQA 2VH3A 3L34A 5L0CA 4LACB 5KYWA 4P6IC 4C7OA 2ETSA 4K0DA 4DXWA 1GM5A 1E2XA 4DRJB 1SZIA 2LFFA 2H7OA 4U5GA 1C02A 3ZTZA 2J45A 4XEFA 1G4US 2C03A 4E18A 2VCBA 4E7ZA 4JJGA 1NG1A 2YLGA 1FMWA 1T6QA 3DAGA 3GM1A 4G7ZF 4MW3A 2HMQA 2XSEA 3LNMB 3POVA 5CIVA 1E84A 4ANJA 3ITFA 5E3AA 1D0ZA 2X0CA 2X51A 2B0JA 4I1MA 1QPUA 3M1CB 4IRUA 4JJFA 3KYIA 1C03A 2HZ8A 3K1HA 3C8GA 4XLNF 3HJCA 4DVYP 2GDCA 2PX3A 3H2UA 1VTMP 4CIHA 4XPYA 5F28E 1RCPA 2BE5F 2WL8A 1ORJA 2Q9CA 1ZYRF 2HKVA 4JEBA 2CNWD 4MVRA 1ZU4A 3AOUA 2ASRA 3B9QA 3JT1A 4BJTA 1HE9A 1LE2A 1E83A 1SR2A 3RQGA 2XXAB 3S27A 4AX2A 4MVSA 5DQZA 1D1BA 2LD6A 4BJ6C 2XXAA 1NU9C 5JT4A 1EQ1A 4Q5SF 4AL1A 3JYHA 5DLJA 1NLXA 3W8HA 3VAYA 3S9OA 5DS4A 5EGYA 4PACA 1Z63A 4JTAB 3E70C 4E0HA 3NKDA 5FCLA 3MX3A 4MTFA 1Z23A 3NMKA 4M63A 4YT2A 4MVOA 2A0UA 5IY5C 4NTBA 2R7UA 2FGYA 4YL3A 4UDVA 4LDQA 2HUJA 2J9BA 4X0RA 3H2VA 3M4BA 3ASOC 1Q0MA 1ST6A 2VC9A 4J30B 4U5EE 4JTCB 1WN0A 2KNHA 1DOWA 2FAPB 2YLDA 4I3MA 3WHNA 3ZG1A 2L9JA 4CDVA 2HV7A 1ZU5A 1MMGA 2LQGA 1LM3B 4AE4B 4U9DA 1BR2A 2J8WA 2CDQA 3FVYA 4QDLA 3HLZA 1LE4A 2YL1A 2WZGA 3T4RA 2EILC 3GODA 2F22A 3N24A 4AE4A 1H7IA 4C3DA 4BJ1A 4PJLA 3M79A 3A11A 3DKAA 4Q7CA 3ZQVA 3U0CA 2EPMX 4NTFA 3ZVRA 5A6BD 2Y3DA 1QZXA 1WASA 2L6FA 2HJMA 2YL0A 3I5QA 4LLCA 5EK0A 4CSAA 3CSKA 3G50A 4YL1A 3B0PA 4G7OF 4PR9A 2NUTA 3S90A 2Y3GA 1XZPA 1B68A 3AQBA 3U3BA 2GAQA 2W9YA 3QZCA 4PJNA 4EHPA 3AG3C 3ZSUA 3B0VC 3QW0A 1NSGB 1RJ9B 5DS6A 1JOGA 3R7CA 1HMDA 4BJ5A 1D0XA 3Q6MA 5TJ5E 4OD4A 5D92A 4QI0A 2R7XA 1YA9A 1RJ9A 1V4AA 4R32A 3EZHA 4OINF 1XWJA 4DRHB 1CGNA 5KYXB 1G5ZA 2YWAA 3KYJA 2NSFA 2P7VA 2JD3A 5A69A 1MNDA 1ZW3A 1T6IA 3M4CA 1BBHA 2VCAA 2EPOA 3O6XA 4CDYA 2G3VA 3AGUA 3EQLF 3G4ZA 3RFYA 3EG9B 3TQOA 2EINC 1HE1A 2OOCA 5JVEA 2J0WA 3GWNA 1Q0FA 1Y4CA 1O87A
chains in the Genus database with same CATH topology
4WABA 2H8AA 4JC7A 4AL0A 2PNOA 4BPMA 4J7TA 3PCVA 2UUHA 5BQIA 4AL1A 3B29A 2UUIA 3LEOA 5BQHA 5BQGA 4YK5A 3HKKA 4NTFA 5K0IA 2Q7RA 3DWWA 4NTBA 4YL3A 4JRZA 4JCZA 4YL1A 4YL0A 5HV9A 4J7YA 4NTAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WAB A;  2H8A A;  4JC7 A;  4AL0 A;  2PNO A;  4BPM A;  4J7T A;  3PCV A;  2UUH A;  5BQI A;  4AL1 A;  3B29 A;  2UUI A;  3LEO A;  5BQH A;  5BQG A;  4YK5 A;  3HKK A;  4NTF A;  5K0I A;  2Q7R A;  3DWW A;  4NTB A;  4YL3 A;  4JRZ A;  4JCZ A;  4YL1 A;  4YL0 A;  5HV9 A;  4J7Y A;  4NTA A; 
#chains in the Genus database with same CATH topology
 2DI3 A;  4CJG A;  2VAS A;  5L0H A;  4FWV A;  2R7R A;  3SP1 A;  1LPE A;  2KYH A;  4RBN A;  1I5N A;  1OW8 A;  2ZXW C;  2J9W A;  3K7D A;  3RVY A;  4JVS A;  3WOD F;  2KSF A;  3GOR A;  2LSE A;  1Q0D A;  1CPQ A;  3S0X A;  1ZW2 A;  3DM5 A;  2HFI A;  4PJJ A;  1RMV A;  2R7O A;  4N6C A;  3V7O A;  2YL7 A;  4CDA A;  5L0I A;  3FOO A;  4H54 A;  4MVM A;  1LIH A;  2LCH A;  1M56 C;  1Z6A A;  1IZM A;  1S05 A;  2DB4 A;  3LAY A;  2D4U A;  4MTG A;  3I5P A;  2KQ9 A;  4U5H A;  1OKK D;  1R5I D;  1JPN A;  4RD9 A;  1TFK B;  1TWA A;  2IYL D;  3IQT A;  3TJ6 A;  3UGP A;  2ICW G;  4YL0 A;  3ZIB A;  4ZLD A;  3ABL C;  1OW6 A;  3NYL A;  3QVY A;  2IXM A;  3QTH A;  2XLE A;  1OQC A;  3NG1 A;  5CI9 A;  1I4Z A;  3LS1 A;  1LI7 A;  2Q00 A;  1LS4 A;  3U2L A;  3EGD B;  5GPG B;  2WVQ A;  1W2W A;  2KC3 A;  3MFN A;  4IAQ A;  5B1B C;  1OW7 A;  1QQ3 A;  4XLP F;  2PX0 A;  4KNV A;  4YT5 A;  5DQT A;  3EGD A;  4JEA A;  1YJG A;  3JSE O;  4H4K C;  4LDK A;  3B0U X;  3WG7 C;  3T6B A;  3N0T A;  1H9G A;  1UG7 A;  2CCY A;  1D1C A;  3ZC4 A;  3SXZ A;  3C8G B;  4U5B E;  3MYF A;  2CYD A;  1SF8 A;  3LNR A;  1TR2 A;  4DJ9 A;  4NY3 A;  2FFH A;  2GWW A;  1D0Y A;  3MLG A;  1TKN A;  1DOV A;  2RSE B;  5T3T A;  4YT8 A;  1Y6D A;  3C62 A;  3KPH A;  4NTA A;  1TQG A;  1YYJ A;  3JRT A;  1LI5 A;  2IOQ A;  3DXJ F;  2J9U A;  1A7D A;  1SYQ A;  2OEX A;  3T6J A;  1QVX A;  2PP4 A;  4CBE A;  1TWC A;  2R02 A;  3PHF 2;  1KU2 A;  1Z7Q c;  2P0N A;  2NUP A;  3K6B A;  2L7A A;  1FFH A;  4BPM A;  3SXY A;  4IB4 A;  2AWY A;  1Z3I X;  4W8P A;  3RH3 A;  4CIP A;  3S29 A;  1F1M A;  4HE8 D;  5BQI A;  3TOM A;  2CGE A;  3V5X A;  3CEX A;  4IJJ A;  5KYU B;  1WTY A;  5COF A;  5AC4 A;  3WAQ A;  1L3P A;  2C04 A;  2J9V A;  2YZS A;  3DMD A;  3EPV A;  2QUP A;  4WJ0 A;  4YK5 A;  2EPN A;  4XTK A;  3DZA A;  3DAF A;  5KYU A;  4CS9 A;  4LDR A;  3L1M A;  4DRI B;  1LVK A;  2WB7 A;  5A6K A;  4BEM J;  1M2V B;  2XRH A;  3Q7G A;  1YVI A;  4DOZ A;  3GEH A;  2A68 F;  2Q3T A;  2XLD A;  3X1O A;  4JW1 A;  5E2Q A;  3UR3 C;  3DE8 A;  2RD9 A;  2XL6 A;  4EKW A;  3J06 A;  1FMV A;  1M2V A;  1A7V A;  2YEV A;  2XLO A;  3EHN A;  2QY9 A;  3FMS A;  3RKO F;  3KH2 A;  2D5R B;  4OIO F;  2I8B A;  2GA0 A;  3TUL A;  2JPU A;  1FAP B;  2EPL X;  1J8Y F;  1VYI A;  3PCV A;  3FHD A;  1PV3 A;  3UGO A;  3AG1 C;  3AG2 C;  2OEV A;  2MHR A;  1VLS A;  2QNL A;  3QW1 A;  4E17 A;  5L0G A;  3RVZ A;  2P1A A;  2XLW A;  3T6G B;  4EBK A;  3I4U A;  2HSB A;  3NKE A;  4MW8 A;  5L0J A;  2DYR C;  4A2N B;  3VRC A;  3HNI A;  4Q4Z F;  2XL8 A;  4C3B A;  5K0I A;  3BEH A;  3SNH A;  4CS7 A;  1E85 A;  2NUT B;  1T5O A;  1UFB A;  3T9O A;  3OA1 A;  4U5C E;  2YQY A;  3K1I A;  3JCU Q;  4E0I A;  3DJN B;  1NFN A;  1JAF A;  1RKE B;  2GFH A;  3RIP A;  3SYN A;  4YN0 B;  2M64 A;  4CS9 C;  4JUR I;  4BG0 A;  1OCO C;  3EZI A;  2QTV A;  3NYJ A;  4PFO A;  2XS8 A;  4AL0 A;  3W2V A;  2E87 A;  3EFO B;  1PD1 A;  1RKE A;  3FXH A;  4DBR A;  1TFO B;  2A0B A;  1M57 C;  4Z9I A;  4U9E A;  2PNO A;  4JCH A;  2HS5 A;  3C63 A;  4GQH A;  4XPW A;  3EFO A;  3TD7 A;  1BZ4 A;  3DI5 A;  4DBQ A;  4FX5 A;  1G4W R;  4GEH A;  3TJ5 A;  1ORS C;  3LUT B;  5JRA A;  4JZA A;  3PDM P;  2W4B A;  4JIO A;  1WAT A;  2R9R B;  1I4Y A;  3HNJ A;  4MS2 A;  1BR4 A;  1M2O A;  2A6H F;  2LFD A;  2R05 A;  1YDI A;  2L81 A;  3K66 A;  3OWT A;  5CI8 A;  1E86 A;  1IW7 F;  4G78 A;  1YLM A;  3W4Y A;  3N2Z B;  3KKB A;  4EBJ A;  1MMN A;  4KC9 A;  5COM A;  1ZHY A;  1N1C A;  2TMV P;  2OCC C;  3RW0 A;  3W2W A;  2Q9B A;  3ECS A;  3W8I A;  5A6J A;  4OIP F;  1YYX A;  3FDQ A;  3O10 A;  1LS1 A;  1KTM A;  2ZXP A;  1OXK A;  4CSA C;  4G7H F;  5F5F A;  3K1I C;  2IXP A;  4YT4 A;  2Z15 A;  3RF3 A;  3UNG C;  1LKX A;  1FFT C;  2YHS A;  1A41 A;  3LJB A;  1NZE A;  3LS0 A;  4PJM A;  4XEV A;  4L6R A;  5T3W A;  2BL2 A;  2IM8 A;  5L0F A;  4XWJ A;  2UUH A;  1U6H A;  5B3I A;  4BEJ A;  4IAO A;  4J32 B;  1U89 A;  4D4N A;  2J7P A;  3SXK A;  4BJ5 C;  2YVK A;  3VYW A;  3NMI A;  4MVZ A;  4XPX A;  5JSL A;  2EIK C;  3PMR A;  2XL4 A;  1JR8 A;  3U5S A;  2O9X A;  3GEE A;  3GAN A;  2J0X A;  2H7V C;  3NMJ A;  1M6T A;  2AVK A;  3C7J A;  4OD5 A;  5E3C A;  3U3F A;  3RYL A;  2XM4 A;  3VM6 A;  2EIJ C;  2WZF A;  4O7G A;  1APC A;  2HV6 A;  4EIY A;  1ZHT A;  4O6M A;  1CPR A;  3C8G D;  2HJ3 A;  1O3U A;  2BC5 A;  3HNL A;  4NC3 A;  3AG4 C;  3IQ5 A;  1QLE C;  4A4A A;  1TWG A;  3CQZ A;  3IQC A;  3LLK A;  4MTO A;  3LEO A;  2R7S A;  4JE9 A;  5BQH A;  2R7T A;  3KL4 A;  2XM0 A;  3L0I A;  3RQF A;  5A6A A;  2L6H A;  1BR1 A;  3AJM A;  2H7B A;  2ZD9 A;  3GM3 A;  4I44 A;  4ULV A;  3A9C A;  2R03 A;  4YJW A;  4Z9H A;  5BQG A;  3V5Z A;  4D4X A;  5AGF A;  2IXO A;  4W8K A;  3U2M A;  3U9M A;  1U0B B;  1T6U A;  1EKY A;  1GQA A;  3CZ6 A;  3UMI A;  4DVZ A;  4MVU A;  3B29 A;  5HV9 A;  2OU6 A;  2ZXO A;  1VOM A;  4WAB A;  1H6G A;  3EHM A;  2NUP B;  1WWP A;  1Z5Z A;  3DJU B;  1YAR O;  3O55 A;  2KJG A;  2Q9A A;  1WGW A;  3IHU A;  4U5F E;  1FNT c;  3KMI A;  5AC5 A;  3QMK A;  2XLH A;  2P6V A;  3JRM O;  3IEE A;  4IGG A;  3EJN A;  4NCQ A;  1K05 A;  3IQ6 A;  1PD0 A;  2PFD A;  3DD7 A;  3SXM A;  2DGJ A;  1BDJ B;  2OQM A;  4EUK B;  2UUI A;  4EWC A;  4JTD B;  1JRA A;  2Y3B A;  4N6H A;  1OKK A;  4N06 A;  1VK5 A;  4WGZ A;  3SEO A;  2L6G A;  4HFF B;  2R25 A;  3TOL A;  3TK0 A;  5KYY B;  2WVN A;  3BRJ A;  3JZ0 A;  2R7Q A;  4O6N A;  3S28 A;  3GWL A;  3QVZ A;  3EH1 A;  5JUA A;  3JYY A;  4JCZ A;  4P9T A;  5T1D B;  2PF4 E;  2AWC A;  4K1O A;  4O6Y A;  3U8V A;  3L8I A;  2AU5 A;  3VF0 A;  5KYY A;  1RKC A;  3GEI A;  5D91 A;  4U5D E;  1ZHW A;  1QSP A;  1MNE A;  3MYI A;  4MQ9 F;  3F47 A;  3ZQY A;  2V26 A;  3UMK A;  4G0H A;  2W4M A;  4OIQ F;  5BUO A;  3C8Z A;  4MND A;  1V54 C;  1H9T A;  1MMA A;  4FES A;  1S7Z A;  2LP4 A;  3NRH A;  2PBE A;  2ZPA A;  3ABM C;  3AQC A;  3M15 A;  1T9K A;  3DM9 B;  1YA7 O;  3FAJ A;  2XS1 A;  1AEP A;  2G62 A;  3GM2 A;  2NPU A;  4I1O B;  4OIR F;  2WZL A;  1FR0 A;  2Q7R A;  1HW1 A;  2YRF A;  1OXB A;  4XQ1 A;  3U9J A;  2V3C C;  1K04 A;  1R4T A;  2AP3 A;  2NSG A;  3O39 A;  2A1D D;  2CNW A;  1HW2 A;  5HSW A;  2YL3 A;  4AK9 A;  1A7E A;  4JC7 A;  1SMY F;  4EBB A;  1YZA A;  4O79 A;  4ULW A;  1ORY A;  2I15 A;  3ZDL A;  2HMZ A;  4PFP A;  2Y39 A;  2R7W A;  3H65 A;  2P61 A;  1KNY A;  4QI2 A;  5DS5 A;  1ZHX A;  4J7T A;  4MVQ A;  2VB6 A;  1MQV A;  1JMW A;  4RDA A;  1MMD A;  4WGY A;  3NDB B;  2LIG A;  3ABK C;  2XLV A;  5EHH A;  2QE9 A;  2EIM C;  3LES A;  4ZLC A;  2R7V A;  2KGO A;  5JP7 A;  1VB5 A;  3EH2 A;  2EPK X;  3HKK A;  2CW0 F;  3OEO A;  1OR2 A;  4P9F A;  1EA8 A;  2J7P D;  3UMH A;  2JX0 A;  1OCC C;  1HY5 A;  1VYK A;  2G3K A;  2Y69 C;  4F4B A;  1RXQ A;  4FAP B;  1A0B A;  1NBB A;  3Q6N A;  1ZHZ A;  3FOP A;  4JRZ A;  1K40 A;  2HSQ A;  5JS5 A;  1O5H A;  2A6E F;  5COG A;  1CGO A;  1QKR A;  1CGM E;  4IWB A;  2H8A A;  4YWQ A;  3E9V A;  1ZVZ A;  2M4E A;  2DYS C;  2Y3H A;  5B1A C;  4CS8 A;  1V55 C;  3C18 A;  2NG1 A;  3L8J A;  3K33 A;  1VLT A;  4HFK B;  1YAU O;  4K7B A;  3V5Y A;  3S84 A;  3FAP B;  5B3S C;  2VCC A;  4LER A;  4LLE A;  1G8X A;  4HEA J;  5FZT A;  5A6B A;  3JSZ A;  3HTK C;  2MWQ A;  1HMO A;  3X2Q C;  5E33 A;  3ZWI A;  1TWH A;  5KYX A;  1XZQ A;  1V74 B;  2A69 F;  4IAR A;  4N4W A;  5JLI A;  1OCZ C;  2IXN A;  2W45 A;  1NU7 D;  1L7C A;  3DWW A;  3LEV A;  4C3E A;  1JPJ A;  2YLI A;  4J7Y A;  1Q0K A;  2Q4F A;  3EG9 A;  256B A;  3NYM A;  4Z9J A;  5L3V A;  4E7S A;  5L3Q A;  3G4X A;  3US6 A;  1J8M F;  1YZC A;  1C17 M;  3AGT A;  1OR3 A;  1GGQ A;  3ATP A;  2OJE D;  5KYN A;  2OG2 A;  4KNW A;  3EGX B;  1AUE A;  3U8P A;  2B0H A;  2WVO A;  2OKU A;  3F46 A;  5F5H A;  1NFO A;  2YKZ A;  3EGX A;  3LLI A;  3MBG A;  1PCX A;  4CS8 C;  4ONS A;  3R2P A;  4XEK A;  3RQE A;  2MYS A;  1FTS A;  4JKV A;  4ER9 A;  4B6I A;  3DE9 A;  1T01 A;  5DVW A;  3ZTM A;  2KK1 A;  2XLM A;  4CJO A;  4PK4 A;  1D1A A;  3B71 A;  3SZR A;  3JTL O;  2LK4 A;  1VMA A;  5L0D A;  2QLA A;  1Q0G A;  1AVO B;  2IBF A;  4GYT A;  4NQF A;  3CAX A;  4CX9 A;  1ZZP A;  1WOL A;  1EI7 A;  5KYW B;  4C7O B;  2ZXR A;  4KBL A;  3ASN C;  1GS9 A;  4KI2 A;  3Q7L A;  2KW3 C;  3HNK A;  1OCR C;  3IPM O;  2J46 A;  4BJ6 A;  2OJQ A;  2VH3 A;  3L34 A;  5L0C A;  4LAC B;  5KYW A;  4P6I C;  4C7O A;  2ETS A;  4K0D A;  4DXW A;  1GM5 A;  1E2X A;  4DRJ B;  1SZI A;  2LFF A;  2H7O A;  4U5G A;  1C02 A;  3ZTZ A;  2J45 A;  4XEF A;  1G4U S;  2C03 A;  4E18 A;  2VCB A;  4E7Z A;  4JJG A;  1NG1 A;  2YLG A;  1FMW A;  1T6Q A;  3DAG A;  3GM1 A;  4G7Z F;  4MW3 A;  2HMQ A;  2XSE A;  3LNM B;  3POV A;  5CIV A;  1E84 A;  4ANJ A;  3ITF A;  5E3A A;  1D0Z A;  2X0C A;  2X51 A;  2B0J A;  4I1M A;  1QPU A;  3M1C B;  4IRU A;  4JJF A;  3KYI A;  1C03 A;  2HZ8 A;  3K1H A;  3C8G A;  4XLN F;  3HJC A;  4DVY P;  2GDC A;  2PX3 A;  3H2U A;  1VTM P;  4CIH A;  4XPY A;  5F28 E;  1RCP A;  2BE5 F;  2WL8 A;  1ORJ A;  2Q9C A;  1ZYR F;  2HKV A;  4JEB A;  2CNW D;  4MVR A;  1ZU4 A;  3AOU A;  2ASR A;  3B9Q A;  3JT1 A;  4BJT A;  1HE9 A;  1LE2 A;  1E83 A;  1SR2 A;  3RQG A;  2XXA B;  3S27 A;  4AX2 A;  4MVS A;  5DQZ A;  1D1B A;  2LD6 A;  4BJ6 C;  2XXA A;  1NU9 C;  5JT4 A;  1EQ1 A;  4Q5S F;  4AL1 A;  3JYH A;  5DLJ A;  1NLX A;  3W8H A;  3VAY A;  3S9O A;  5DS4 A;  5EGY A;  4PAC A;  1Z63 A;  4JTA B;  3E70 C;  4E0H A;  3NKD A;  5FCL A;  3MX3 A;  4MTF A;  1Z23 A;  3NMK A;  4M63 A;  4YT2 A;  4MVO A;  2A0U A;  5IY5 C;  4NTB A;  2R7U A;  2FGY A;  4YL3 A;  4UDV A;  4LDQ A;  2HUJ A;  2J9B A;  4X0R A;  3H2V A;  3M4B A;  3ASO C;  1Q0M A;  1ST6 A;  2VC9 A;  4J30 B;  4U5E E;  4JTC B;  1WN0 A;  2KNH A;  1DOW A;  2FAP B;  2YLD A;  4I3M A;  3WHN A;  3ZG1 A;  2L9J A;  4CDV A;  2HV7 A;  1ZU5 A;  1MMG A;  2LQG A;  1LM3 B;  4AE4 B;  4U9D A;  1BR2 A;  2J8W A;  2CDQ A;  3FVY A;  4QDL A;  3HLZ A;  1LE4 A;  2YL1 A;  2WZG A;  3T4R A;  2EIL C;  3GOD A;  2F22 A;  3N24 A;  4AE4 A;  1H7I A;  4C3D A;  4BJ1 A;  4PJL A;  3M79 A;  3A11 A;  3DKA A;  4Q7C A;  3ZQV A;  3U0C A;  2EPM X;  4NTF A;  3ZVR A;  5A6B D;  2Y3D A;  1QZX A;  1WAS A;  2L6F A;  2HJM A;  2YL0 A;  3I5Q A;  4LLC A;  5EK0 A;  4CSA A;  3CSK A;  3G50 A;  4YL1 A;  3B0P A;  4G7O F;  4PR9 A;  2NUT A;  3S90 A;  2Y3G A;  1XZP A;  1B68 A;  3AQB A;  3U3B A;  2GAQ A;  2W9Y A;  3QZC A;  4PJN A;  4EHP A;  3AG3 C;  3ZSU A;  3B0V C;  3QW0 A;  1NSG B;  1RJ9 B;  5DS6 A;  1JOG A;  3R7C A;  1HMD A;  4BJ5 A;  1D0X A;  3Q6M A;  5TJ5 E;  4OD4 A;  5D92 A;  4QI0 A;  2R7X A;  1YA9 A;  1RJ9 A;  1V4A A;  4R32 A;  3EZH A;  4OIN F;  1XWJ A;  4DRH B;  1CGN A;  5KYX B;  1G5Z A;  2YWA A;  3KYJ A;  2NSF A;  2P7V A;  2JD3 A;  5A69 A;  1MND A;  1ZW3 A;  1T6I A;  3M4C A;  1BBH A;  2VCA A;  2EPO A;  3O6X A;  4CDY A;  2G3V A;  3AGU A;  3EQL F;  3G4Z A;  3RFY A;  3EG9 B;  3TQO A;  2EIN C;  1HE1 A;  2OOC A;  5JVE A;  2J0W A;  3GWN A;  1Q0F A;  1Y4C A;  1O87 A; 
#chains in the Genus database with same CATH homology
 4WAB A;  2H8A A;  4JC7 A;  4AL0 A;  2PNO A;  4BPM A;  4J7T A;  3PCV A;  2UUH A;  5BQI A;  4AL1 A;  3B29 A;  2UUI A;  3LEO A;  5BQH A;  5BQG A;  4YK5 A;  3HKK A;  4NTF A;  5K0I A;  2Q7R A;  3DWW A;  4NTB A;  4YL3 A;  4JRZ A;  4JCZ A;  4YL1 A;  4YL0 A;  5HV9 A;  4J7Y A;  4NTA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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