4O24A

Dna double-strand break repair pathway choice is directed by distinct mre11 nuclease activities
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
331
structure length
331
Chain Sequence
IHHHHHHVINLKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGNHDWKGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPDESEALRKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAGYAGIEQGREIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNFPGYVRVVYEEDSGILPDLMGEIDNLVKIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities.
pubmed doi rcsb
molecule tags Dna binding protein/inhibitor
source organism Thermotoga maritima
molecule keywords Exonuclease, putative
total genus 101
structure length 331
sequence length 331
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.160.210 Alpha Beta 2-Layer Sandwich Double Stranded RNA Binding Domain DNA double-strand break repair nuclease 4o24A02
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 4o24A01
4J6OA 3AV0A 2NYLC 3LL8A 3DSCA 1G5BA 2ZBMA 4O4KA 3K7VC 4ORBA 1V73A 4ZVZA 2Q8UA 1T71A 4I5NC 3H67A 1SU1A 2CV9A 2WDEA 3EGGA 5C1VA 1S70A 4V0VA 4DT2A 4UT3A 2BQ8X 5IOHA 4JA7A 4LTYA 2BDXA 4LU9A 2Z72A 2YVTA 4ORAA 3T1IA 4O24A 5INBA 4FCXA 1OIEA 5GTUA 2IAEC 3C5WC 3IVDA 1T70A 2P6BA 1WARA 5JPEA 3QFNA 3H66A 2Z06A 3QFKA 4UT3B 2XMOA 1Z2XA 3H60A 3PSNA 3RL5A 3H69A 4DHLA 3IVEA 3TGHA 1MF8A 2IE4C 2JOGA 4Q7FA 4MP0A 3RL3A 1UF3A 2Z1AA 4FBQA 3ZU0A 4DSYA 3H64A 1TCOA 4H2FA 4JA9A 3HVQA 3RL4A 3K7WC 4WWLA 3IB8A 4O5GA 1WAO1 1XZWA 2NPPC 1AUIA 4MOVA 2QJCA 4LACC 4H1SA 4NZVA 3CK2A 1HPUA 4YKEA 1Z2WA 2A22A 4HD0A 4OR9A 4UT2A 3GVEA 1UTEA 3H61A 4V0WA 2GJUA 2O8AA 1U32A 1JK7A 1S95A 4I5LC 3RQZA 3V4YA 4B2OA 5J28A 1HP1A 2HY1A 4IL1A 2QFRA 3N5UA 2HYOA 4M0VA 2BCDA 4H2IA 1IT6A 4XPNA 3THNA 3DSDA 1II7A 3C9FA 3DW8C 4UWQA 4FBKA 3QFOA 5EQVA 3H68A 4F0ZA 3KBPA 4G9JA 3QG5C 3ZTVA 4ZX2A 1HO5A 3THOB 1S3LA 1QFCA 2NYMC 1OI8A 4IYPC 2R17A 1KBPA 1QHWA 2WDDA 3IB7A 3H63A 1NNWA 3H62B 3P71C 4ORCA 4TUIA 1FJMA 3ICFA 1OIDA 3EGHA 1USHA 5F3WA 3E7AA 3PSOA 1XM7A 5HPEA 3AUZA 4KKZA 4KBPA 1S3NA 4FBWA 3E7BA 5JPFA 4TUGA 2AHDA 4H1YP 2QFPA 4H2GA 5JJTA 5DNYA 3JYFA 3QFMA 4V0XA 2WDCA 2DFJA 3FGAC 1S8EA 4O43A 2NXFA 5B8IA 1W24A 2USHA 2O8GA 2HYPA 2IE3C 1S3MA 1M63A 4H2BA 4MOYA 2WDFA 2KKNA
chains in the Genus database with same CATH superfamily
3EQ1A 4BMJA 5IT9C 1DI2A 3DSCA 5KL4A 3J7Yp 3KWRA 4I5NC 3H67A 3BF2A 2LCEA 2JP9A 2WBUA 4JI8E 2L3JA 5IOHA 1Z1BA 4F9CB 1T4OA 1NCSA 3BGHA 2UXBE 2DIXA 4BHCA 4ORAA 2I9IA 2LRSA 1NEIA 1XNQE 5IWAE 5FLXC 1G2DC 1RC7A 3C5WC 2DRPA 2DB2A 2JPAA 5JPEA 2CPNA 4KZSA 2M7QA 2L2NA 3UK3C 4HEIA 1YZ9A 3H60A 1TN9A 3RL5A 4DHLA 3IVEA 1MF8A 1YPNA 3MHHC 3VYXA 4FBQA 2EPXA 4DSYA 1BBOA 3H64A 1ZAAC 1TCOA 1BBGA 3IB8A 1AAYA 2RTXA 3M99B 3HXLA 1AUIA 2ELZA 1PDAA 5A6BA 2EPAA 2RQLA 2QJCA 1O0WA 4JV5E 4LACC 2EPZA 1HPUA 2EL6A 1X49A 3IWDA 2A22A 2EL4A 2NUGA 4I8OA 2M4IA 4OX9E 1N32E 5AC5A 2O8AA 1U32A 5J28A 3V4YA 2M1SA 1KYQA 4IL1A 5KL7A 2EPKX 4KHPE 2QFRA 3HPZA 3KZYA 4X62E 2EM2A 4DR4E 2NABA 3DJWA 1QU6A 4DV5E 2EM6A 3HTXA 5EQVA 2V85A 4P78A 2EQ3A 3ZTVA 2YTOA 4X64E 4ZX2A 2VQEE 1S3LA 1RMDA 4LF6E 2V89A 4GEQB 2EOZA 1QHWA 2DXNA 4WXCA 4TUIA 1RQ0A 2EMHA 1FJMA 3EGHA 2B3TB 3PSOA 3ADGA 2EMWA 2WCC3 2EZ6A 1X3CA 2EORA 4KBPA 3VYYA 1S3NA 3IWBA 1STUA 1N33E 4P7DA 4F9AB 4H1YP 5JJTA 2DSYA 5DNYA 4JI3E 2ODRC 1T38A 1EH8A 2EN4A 2R1FA 4L8NA 2LV2A 3FGAC 5LMNE 1UHZA 5B8IA 3L00A 4WXDA 2KOUA 4BHBA 1YSAC 2USHA 2HYPA 2IE3C 1X48A 2O8GA 2BBGA 2EOOA 1YFHA 1F2IG 4H2BA 2EOXA 1X6FA 1PKPA 4KWYA 5ADZA 2MKDA 4J6OA 2EPNA 4BC7A 1IBME 3ADLA 3H09A 2E1MA 1N3GA 2EPRA 3C6KA 4WFTA 4O4KA 2ZBMA 4ORBA 1V73A 2NA2A 3ZOQB 2Q8UA 4X8WA 4DR7E 2LO3A 2EMAA 4JI7E 1T71A 4F9BB 2EN3A 2FV4B 2EOHA 4Q35B 4GKJE 2ZOAA 3EGGA 5C1VA 4V0VA 4M2ZA 2YWQA 4UT3A 2BQ8X 3C4TA 4LTYA 1X6EA 2BDXA 1T4LB 5BR8E 5AE3A 2YTIA 3EPKA 2I13A 5INBA 4O24A 4FCXA 1N36E 5GTUA 2YT4A 2EQ0A 2V83A 2EN6A 2EL5A 1YYKA 2E72A 2EOJA 3H66A 2DGCA 2JWOA 1HNWE 1WXRA 2MC5A 5KL2A 1Z2XA 3H69A 2K7IA 2LBSB 5LMUE 1UF3A 2UUAE 2EM9A 3RL4A 2LMZA 1EKZA 1WAO1 2LTRA 1ZBTA 2NPPC 1MEYC 2ODRD 4MOVA 2YTFA 1T39A 2EMGA 4YKEA 4HD0A 3VK6A 5A6JA 2EP3A 1A1KA 1UTEA 1WHNA 2DMYA 5AASA 3J80C 3H61A 2GJUA 2EWLA 1S95A 4B2OA 4FK5C 2YPNA 1TF3A 2JOXA 2EOMA 2ELYA 4DR3E 2YRHA 4M0VA 2YU8A 1IT6A 2ZM6E 4NXNE 4GKKE 3THNA 3DSDA 2EMYA 2FTXB 4F6MA 3QFOA 2EPCA 1HNZE 2F4VE 3QG5C 3KBPA 2L6MA 3THOB 4BC9A 1GZ6A 4F54A 1A1IA 4R2EA 1UBDC 2LT7A 3IB7A 3H63A 1NNWA 1DQ3A 4BS9A 2N3HA 5A69A 2EN2A 4LF7E 1IBKE 4LFCE 1OIDA 1X5WA 2EM7A 5F3WA 2G7HA 2B7TA 2ENCA 2YZTA 2MC6A 5HPEA 2ENAA 2JYAA 4R2AA 1SFEA 1IQOA 4DR2E 4F6NA 1YYWA 2UXDE 3ADIA 4K0KE 5JPFA 2CSHA 2EM5A 2UUCE 4B3SE 4V0XA 2ZO9B 4BCAA 1S8EA 4DV4E 4LF4E 4JI6E 4NXME 3E0JA 4DR1E 3TQMA 2EM4A 3T1HE 3LMLA 2WDFA 2EM8A 2KHXA 3AV0A 4R2QA 2LUQA 1YUJA 3K7VC 2A25A 1FJGE 1EH7A 5LLQA 3BIDA 1ZR9A 2EE8A 1X47A 1SU1A 4HTGA 2L3CA 2CV9A 1S70A 2GPIA 4DT2A 2RSMA 1ZBQA 2UUBE 4JA7A 5IV8B 4LU9A 2Z72A 3T1IA 2HGHA 3EPHA 2JVAA 2L33A 4WX9A 1HNXE 2HHHE 2IAEC 2YTDA 4R2CA 3IVDA 3DF6A 2EN8A 5CFFE 2JOBA 2Z06A 3QFKA 3PSNA 2LTSA 1GTKA 2RS6A 2VE7C 2VRDA 2VF1A 3RL3A 2IE4C 2V86A 2Z1AA 2HC5A 4YY3E 2L8TA 1G2FC 1DGCA 4H2FA 2WBTA 2E5LE 4DV0E 4O5GA 1XNRE 4JI2E 4M9VC 2V8QB 2EMZA 4F2JC 1GQEA 1XZWA 4H1SA 2JR1A 4NZVA 4MLVA 2DLKA 2EOSA 1T4NA 2LJHA 1BB8A 3MHSC 4V0WA 1JK7A 4I5LC 1QNTA 2YRMA 1A1HA 2HY1A 1A1GA 2YTEA 5AC4A 1JK2A 1KJKA 2ADRA 2BCDA 4L5NC 4RHBB 2UXCE 3FLOA 2YU5A 4WSGA 1XMOE 4FBKA 4UWQA 3RMPA 3JU0A 2LVHA 4G9JA 5KL6A 4R2PA 3J81C 3EPJA 5T6JA 2NYMC 2EMXA 4MLQA 4LF9E 2WDDA 3P71C 3ICFA 4DV6E 4B3TE 2ENHA 4DV7E 2YTPA 2EMCA 1USHA 4IJDA 3E7AA 2NUEA 1PJSA 4R2DA 3P1XA 1XM7A 1B69A 4R2SA 3T1YE 4Q28A 2EOYA 4KKZA 3EPLA 3OMLA 3F6HA 4DV3E 2LE2A 1X6HA 2QFPA 3JTZA 2YSOA 4AQYE 2EMLA 2GLIA 3JYFA 2YRKA 5TSEA 2DFJA 5A6KA 4YHHE 4B3RE 1UN6B 5A6BD 1WJPA 2CT1A 4WSPA 5A6AA 2YTQA 2PRTA 4JI5E 4DUYE 1M63A 2DLQA 3K7WC 2EQ1A 4MOYA 2YTNA 3HPSA 3MSWA 2NYLC 3LL8A 1G5BA 2EM3A 4ZVZA 2L92A 4ZYDA 5KL3A 3ADJA 1UILA 2EOFA 2MDRA 2WDEA 4JYAE 4OOGC 4JI1E 3OTOE 2FGGA 2K4VA 4LFAE 4IS1C 2RS7A 2YVTA 2B7VA 4DV2E 1OIEA 4X9JA 3JAMC 2KONA 1T70A 2P6BA 4DUZE 1WARA 1A1JA 2EN7A 2N8XA 1TF6A 2V87A 5A2QC 3QFNA 1IQSA 4ZYEA 3J7AG 1WRJA 1EH6A 4UT3B 1XMQE 2YTGA 2XMOA 2UU9E 4J8ZA 2EJ4A 1L4SA 3TGHA 1PJQA 3FIGA 2JOGA 4Q7FA 3LLHA 4MP0A 2V88A 3ZU0A 2EMBA 1MGTA 2VQFE 2WBSA 2DXLA 4JA9A 2YEQA 1LLMC 5AE1A 3HVQA 4WWLA 1WHQA 3VHTB 1FKAE 2RPCA 5KL5A 2B9DA 2DMIA 2GHFA 2RSIA 2EPLX 1YUIA 2EOEA 3CK2A 1Z2WA 2D9HA 3C4BA 4OR9A 4UT2A 2EMIA 3IWCA 3GVEA 3KZZA 4WYQB 5IXMB 1A1LA 4DV1E 3ECRA 2MKNA 2EPPA 2MDGA 1HP1A 1ZU1A 2IHR1 1P47A 3N5UA 2HYOA 4DMIA 4H2IA 2JXPA 2HJJA 4BBYA 4XPNA 2LJUA 1A1FA 4DKKA 1II7A 3C9FA 3DW8C 4M30A 5LL6R 2L2KB 2YTJA 3H68A 4F0ZA 2JY9A 2EPOA 1HO5A 1N34E 2M9AA 1QFCA 2H36X 2LUPB 2EPUA 1OI8A 1YYOA 2J7JA 1KBPA 2R17A 4IYPC 4ORCA 3H62B 2L2MA 1IBLE 2WZOA 4LF5E 3HQ1A 2EMKA 4NHRA 4RH8A 1J5EE 1AH5A 3BBGA 2EOIA 1JK1A 3AUZA 4DR5E 1PJTA 1HR0E 4JI0E 2EOQA 4LFBE 4JI4E 4ZYGA 4FBWA 3E7BA 4X65E 4R8OA 4TUGA 1IMUA 4N4RB 2AHDA 4H2GA 4R03A 2EPMX 2CTDA 2YSPA 2NUFA 2EM0A 2R76A 2BB8A 3QFMA 3F6GA 4GZNC 2WDCA 4R2RA 1SR9A 3C6MA 4O43A 4WPYA 3K6QA 1I94E 4LF8E 2NXFA 4B3ME 1W24A 3D03A 4DR6E 2EN1A 2EMFA 2N3GA 1S3MA 2F8BA 4X66E 4ZYHA 3RQZA 5AE2A 2KKNA 1J26A
chains in the Genus database with same CATH topology
4J6OA 3AV0A 2NYLC 3LL8A 3DSCA 1G5BA 2ZBMA 4O4KA 3K7VC 4ORBA 1V73A 4ZVZA 2Q8UA 1T71A 4I5NC 3H67A 1SU1A 2CV9A 2ZOAA 2WDEA 3EGGA 5C1VA 1S70A 4V0VA 4DT2A 4UT3A 2BQ8X 5IOHA 4JA7A 4LTYA 2BDXA 4LU9A 2Z72A 2YVTA 4ORAA 3T1IA 4O24A 5INBA 4FCXA 1OIEA 5GTUA 2IAEC 3C5WC 3IVDA 1T70A 2P6BA 1WARA 5JPEA 3QFNA 3H66A 2Z06A 3QFKA 4UT3B 2XMOA 1Z2XA 3H60A 3PSNA 3RL5A 3H69A 4DHLA 3IVEA 3TGHA 1MF8A 2IE4C 2JOGA 4Q7FA 4MP0A 3RL3A 1UF3A 2Z1AA 4FBQA 3ZU0A 4DSYA 3H64A 1TCOA 2DXLA 4H2FA 4JA9A 2YEQA 3HVQA 3RL4A 3K7WC 4WWLA 3IB8A 4O5GA 1WAO1 1XZWA 2NPPC 1AUIA 4MOVA 2QJCA 4LACC 4H1SA 4NZVA 3CK2A 1HPUA 4YKEA 1Z2WA 2A22A 4HD0A 4OR9A 4UT2A 3GVEA 1UTEA 3H61A 4V0WA 2GJUA 2O8AA 1U32A 1JK7A 1S95A 4I5LC 3RQZA 3V4YA 4B2OA 5J28A 1HP1A 2HY1A 4IL1A 2QFRA 3N5UA 2HYOA 4M0VA 2BCDA 4H2IA 1IT6A 4XPNA 3DSDA 3THNA 1II7A 3C9FA 3FLOA 3DW8C 4UWQA 4FBKA 3QFOA 5EQVA 3H68A 4F0ZA 3KBPA 4G9JA 3QG5C 3ZTVA 4ZX2A 1HO5A 3THOB 1S3LA 1QFCA 2NYMC 1OI8A 4IYPC 1KBPA 2R17A 2DXNA 1QHWA 2WDDA 3H63A 1NNWA 3H62B 3IB7A 3P71C 4ORCA 1FJMA 3ICFA 4TUIA 1OIDA 3EGHA 1USHA 5F3WA 3E7AA 3PSOA 1XM7A 5HPEA 3AUZA 4KKZA 4KBPA 1S3NA 4FBWA 3E7BA 5JPFA 4TUGA 2AHDA 4H1YP 2QFPA 4H2GA 5JJTA 5DNYA 3JYFA 3QFMA 4V0XA 2WDCA 2DFJA 2ZO9B 1S8EA 3FGAC 4O43A 2NXFA 5B8IA 3E0JA 1W24A 3D03A 2USHA 2O8GA 2HYPA 2IE3C 1S3MA 1M63A 4H2BA 4MOYA 2WDFA 2KKNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J6O A;  3AV0 A;  2NYL C;  3LL8 A;  3DSC A;  1G5B A;  2ZBM A;  4O4K A;  3K7V C;  4ORB A;  1V73 A;  4ZVZ A;  2Q8U A;  1T71 A;  4I5N C;  3H67 A;  1SU1 A;  2CV9 A;  2WDE A;  3EGG A;  5C1V A;  1S70 A;  4V0V A;  4DT2 A;  4UT3 A;  2BQ8 X;  5IOH A;  4JA7 A;  4LTY A;  2BDX A;  4LU9 A;  2Z72 A;  2YVT A;  4ORA A;  3T1I A;  4O24 A;  5INB A;  4FCX A;  1OIE A;  5GTU A;  2IAE C;  3C5W C;  3IVD A;  1T70 A;  2P6B A;  1WAR A;  5JPE A;  3QFN A;  3H66 A;  2Z06 A;  3QFK A;  4UT3 B;  2XMO A;  1Z2X A;  3H60 A;  3PSN A;  3RL5 A;  3H69 A;  4DHL A;  3IVE A;  3TGH A;  1MF8 A;  2IE4 C;  2JOG A;  4Q7F A;  4MP0 A;  3RL3 A;  1UF3 A;  2Z1A A;  4FBQ A;  3ZU0 A;  4DSY A;  3H64 A;  1TCO A;  4H2F A;  4JA9 A;  3HVQ A;  3RL4 A;  3K7W C;  4WWL A;  3IB8 A;  4O5G A;  1WAO 1;  1XZW A;  2NPP C;  1AUI A;  4MOV A;  2QJC A;  4LAC C;  4H1S A;  4NZV A;  3CK2 A;  1HPU A;  4YKE A;  1Z2W A;  2A22 A;  4HD0 A;  4OR9 A;  4UT2 A;  3GVE A;  1UTE A;  3H61 A;  4V0W A;  2GJU A;  2O8A A;  1U32 A;  1JK7 A;  1S95 A;  4I5L C;  3RQZ A;  3V4Y A;  4B2O A;  5J28 A;  1HP1 A;  2HY1 A;  4IL1 A;  2QFR A;  3N5U A;  2HYO A;  4M0V A;  2BCD A;  4H2I A;  1IT6 A;  4XPN A;  3THN A;  3DSD A;  1II7 A;  3C9F A;  3DW8 C;  4UWQ A;  4FBK A;  3QFO A;  5EQV A;  3H68 A;  4F0Z A;  3KBP A;  4G9J A;  3QG5 C;  3ZTV A;  4ZX2 A;  1HO5 A;  3THO B;  1S3L A;  1QFC A;  2NYM C;  1OI8 A;  4IYP C;  2R17 A;  1KBP A;  1QHW A;  2WDD A;  3IB7 A;  3H63 A;  1NNW A;  3H62 B;  3P71 C;  4ORC A;  4TUI A;  1FJM A;  3ICF A;  1OID A;  3EGH A;  1USH A;  5F3W A;  3E7A A;  3PSO A;  1XM7 A;  5HPE A;  3AUZ A;  4KKZ A;  4KBP A;  1S3N A;  4FBW A;  3E7B A;  5JPF A;  4TUG A;  2AHD A;  4H1Y P;  2QFP A;  4H2G A;  5JJT A;  5DNY A;  3JYF A;  3QFM A;  4V0X A;  2WDC A;  2DFJ A;  3FGA C;  1S8E A;  4O43 A;  2NXF A;  5B8I A;  1W24 A;  2USH A;  2O8G A;  2HYP A;  2IE3 C;  1S3M A;  1M63 A;  4H2B A;  4MOY A;  2WDF A;  2KKN A; 
#chains in the Genus database with same CATH topology
 3EQ1 A;  4BMJ A;  5IT9 C;  1DI2 A;  3DSC A;  5KL4 A;  3J7Y p;  3KWR A;  4I5N C;  3H67 A;  3BF2 A;  2LCE A;  2JP9 A;  2WBU A;  4JI8 E;  2L3J A;  5IOH A;  1Z1B A;  4F9C B;  1T4O A;  1NCS A;  3BGH A;  2UXB E;  2DIX A;  4BHC A;  4ORA A;  2I9I A;  2LRS A;  1NEI A;  1XNQ E;  5IWA E;  5FLX C;  1G2D C;  1RC7 A;  3C5W C;  2DRP A;  2DB2 A;  2JPA A;  5JPE A;  2CPN A;  4KZS A;  2M7Q A;  2L2N A;  3UK3 C;  4HEI A;  1YZ9 A;  3H60 A;  1TN9 A;  3RL5 A;  4DHL A;  3IVE A;  1MF8 A;  1YPN A;  3MHH C;  3VYX A;  4FBQ A;  2EPX A;  4DSY A;  1BBO A;  3H64 A;  1ZAA C;  1TCO A;  1BBG A;  3IB8 A;  1AAY A;  2RTX A;  3M99 B;  3HXL A;  1AUI A;  2ELZ A;  1PDA A;  5A6B A;  2EPA A;  2RQL A;  2QJC A;  1O0W A;  4JV5 E;  4LAC C;  2EPZ A;  1HPU A;  2EL6 A;  1X49 A;  3IWD A;  2A22 A;  2EL4 A;  2NUG A;  4I8O A;  2M4I A;  4OX9 E;  1N32 E;  5AC5 A;  2O8A A;  1U32 A;  5J28 A;  3V4Y A;  2M1S A;  1KYQ A;  4IL1 A;  5KL7 A;  2EPK X;  4KHP E;  2QFR A;  3HPZ A;  3KZY A;  4X62 E;  2EM2 A;  4DR4 E;  2NAB A;  3DJW A;  1QU6 A;  4DV5 E;  2EM6 A;  3HTX A;  5EQV A;  2V85 A;  4P78 A;  2EQ3 A;  3ZTV A;  2YTO A;  4X64 E;  4ZX2 A;  2VQE E;  1S3L A;  1RMD A;  4LF6 E;  2V89 A;  4GEQ B;  2EOZ A;  1QHW A;  2DXN A;  4WXC A;  4TUI A;  1RQ0 A;  2EMH A;  1FJM A;  3EGH A;  2B3T B;  3PSO A;  3ADG A;  2EMW A;  2WCC 3;  2EZ6 A;  1X3C A;  2EOR A;  4KBP A;  3VYY A;  1S3N A;  3IWB A;  1STU A;  1N33 E;  4P7D A;  4F9A B;  4H1Y P;  5JJT A;  2DSY A;  5DNY A;  4JI3 E;  2ODR C;  1T38 A;  1EH8 A;  2EN4 A;  2R1F A;  4L8N A;  2LV2 A;  3FGA C;  5LMN E;  1UHZ A;  5B8I A;  3L00 A;  4WXD A;  2KOU A;  4BHB A;  1YSA C;  2USH A;  2HYP A;  2IE3 C;  1X48 A;  2O8G A;  2BBG A;  2EOO A;  1YFH A;  1F2I G;  4H2B A;  2EOX A;  1X6F A;  1PKP A;  4KWY A;  5ADZ A;  2MKD A;  4J6O A;  2EPN A;  4BC7 A;  1IBM E;  3ADL A;  3H09 A;  2E1M A;  1N3G A;  2EPR A;  3C6K A;  4WFT A;  4O4K A;  2ZBM A;  4ORB A;  1V73 A;  2NA2 A;  3ZOQ B;  2Q8U A;  4X8W A;  4DR7 E;  2LO3 A;  2EMA A;  4JI7 E;  1T71 A;  4F9B B;  2EN3 A;  2FV4 B;  2EOH A;  4Q35 B;  4GKJ E;  2ZOA A;  3EGG A;  5C1V A;  4V0V A;  4M2Z A;  2YWQ A;  4UT3 A;  2BQ8 X;  3C4T A;  4LTY A;  1X6E A;  2BDX A;  1T4L B;  5BR8 E;  5AE3 A;  2YTI A;  3EPK A;  2I13 A;  5INB A;  4O24 A;  4FCX A;  1N36 E;  5GTU A;  2YT4 A;  2EQ0 A;  2V83 A;  2EN6 A;  2EL5 A;  1YYK A;  2E72 A;  2EOJ A;  3H66 A;  2DGC A;  2JWO A;  1HNW E;  1WXR A;  2MC5 A;  5KL2 A;  1Z2X A;  3H69 A;  2K7I A;  2LBS B;  5LMU E;  1UF3 A;  2UUA E;  2EM9 A;  3RL4 A;  2LMZ A;  1EKZ A;  1WAO 1;  2LTR A;  1ZBT A;  2NPP C;  1MEY C;  2ODR D;  4MOV A;  2YTF A;  1T39 A;  2EMG A;  4YKE A;  4HD0 A;  3VK6 A;  5A6J A;  2EP3 A;  1A1K A;  1UTE A;  1WHN A;  2DMY A;  5AAS A;  3J80 C;  3H61 A;  2GJU A;  2EWL A;  1S95 A;  4B2O A;  4FK5 C;  2YPN A;  1TF3 A;  2JOX A;  2EOM A;  2ELY A;  4DR3 E;  2YRH A;  4M0V A;  2YU8 A;  1IT6 A;  2ZM6 E;  4NXN E;  4GKK E;  3THN A;  3DSD A;  2EMY A;  2FTX B;  4F6M A;  3QFO A;  2EPC A;  1HNZ E;  2F4V E;  3QG5 C;  3KBP A;  2L6M A;  3THO B;  4BC9 A;  1GZ6 A;  4F54 A;  1A1I A;  4R2E A;  1UBD C;  2LT7 A;  3IB7 A;  3H63 A;  1NNW A;  1DQ3 A;  4BS9 A;  2N3H A;  5A69 A;  2EN2 A;  4LF7 E;  1IBK E;  4LFC E;  1OID A;  1X5W A;  2EM7 A;  5F3W A;  2G7H A;  2B7T A;  2ENC A;  2YZT A;  2MC6 A;  5HPE A;  2ENA A;  2JYA A;  4R2A A;  1SFE A;  1IQO A;  4DR2 E;  4F6N A;  1YYW A;  2UXD E;  3ADI A;  4K0K E;  5JPF A;  2CSH A;  2EM5 A;  2UUC E;  4B3S E;  4V0X A;  2ZO9 B;  4BCA A;  1S8E A;  4DV4 E;  4LF4 E;  4JI6 E;  4NXM E;  3E0J A;  4DR1 E;  3TQM A;  2EM4 A;  3T1H E;  3LML A;  2WDF A;  2EM8 A;  2KHX A;  3AV0 A;  4R2Q A;  2LUQ A;  1YUJ A;  3K7V C;  2A25 A;  1FJG E;  1EH7 A;  5LLQ A;  3BID A;  1ZR9 A;  2EE8 A;  1X47 A;  1SU1 A;  4HTG A;  2L3C A;  2CV9 A;  1S70 A;  2GPI A;  4DT2 A;  2RSM A;  1ZBQ A;  2UUB E;  4JA7 A;  5IV8 B;  4LU9 A;  2Z72 A;  3T1I A;  2HGH A;  3EPH A;  2JVA A;  2L33 A;  4WX9 A;  1HNX E;  2HHH E;  2IAE C;  2YTD A;  4R2C A;  3IVD A;  3DF6 A;  2EN8 A;  5CFF E;  2JOB A;  2Z06 A;  3QFK A;  3PSN A;  2LTS A;  1GTK A;  2RS6 A;  2VE7 C;  2VRD A;  2VF1 A;  3RL3 A;  2IE4 C;  2V86 A;  2Z1A A;  2HC5 A;  4YY3 E;  2L8T A;  1G2F C;  1DGC A;  4H2F A;  2WBT A;  2E5L E;  4DV0 E;  4O5G A;  1XNR E;  4JI2 E;  4M9V C;  2V8Q B;  2EMZ A;  4F2J C;  1GQE A;  1XZW A;  4H1S A;  2JR1 A;  4NZV A;  4MLV A;  2DLK A;  2EOS A;  1T4N A;  2LJH A;  1BB8 A;  3MHS C;  4V0W A;  1JK7 A;  4I5L C;  1QNT A;  2YRM A;  1A1H A;  2HY1 A;  1A1G A;  2YTE A;  5AC4 A;  1JK2 A;  1KJK A;  2ADR A;  2BCD A;  4L5N C;  4RHB B;  2UXC E;  3FLO A;  2YU5 A;  4WSG A;  1XMO E;  4FBK A;  4UWQ A;  3RMP A;  3JU0 A;  2LVH A;  4G9J A;  5KL6 A;  4R2P A;  3J81 C;  3EPJ A;  5T6J A;  2NYM C;  2EMX A;  4MLQ A;  4LF9 E;  2WDD A;  3P71 C;  3ICF A;  4DV6 E;  4B3T E;  2ENH A;  4DV7 E;  2YTP A;  2EMC A;  1USH A;  4IJD A;  3E7A A;  2NUE A;  1PJS A;  4R2D A;  3P1X A;  1XM7 A;  1B69 A;  4R2S A;  3T1Y E;  4Q28 A;  2EOY A;  4KKZ A;  3EPL A;  3OML A;  3F6H A;  4DV3 E;  2LE2 A;  1X6H A;  2QFP A;  3JTZ A;  2YSO A;  4AQY E;  2EML A;  2GLI A;  3JYF A;  2YRK A;  5TSE A;  2DFJ A;  5A6K A;  4YHH E;  4B3R E;  1UN6 B;  5A6B D;  1WJP A;  2CT1 A;  4WSP A;  5A6A A;  2YTQ A;  2PRT A;  4JI5 E;  4DUY E;  1M63 A;  2DLQ A;  3K7W C;  2EQ1 A;  4MOY A;  2YTN A;  3HPS A;  3MSW A;  2NYL C;  3LL8 A;  1G5B A;  2EM3 A;  4ZVZ A;  2L92 A;  4ZYD A;  5KL3 A;  3ADJ A;  1UIL A;  2EOF A;  2MDR A;  2WDE A;  4JYA E;  4OOG C;  4JI1 E;  3OTO E;  2FGG A;  2K4V A;  4LFA E;  4IS1 C;  2RS7 A;  2YVT A;  2B7V A;  4DV2 E;  1OIE A;  4X9J A;  3JAM C;  2KON A;  1T70 A;  2P6B A;  4DUZ E;  1WAR A;  1A1J A;  2EN7 A;  2N8X A;  1TF6 A;  2V87 A;  5A2Q C;  3QFN A;  1IQS A;  4ZYE A;  3J7A G;  1WRJ A;  1EH6 A;  4UT3 B;  1XMQ E;  2YTG A;  2XMO A;  2UU9 E;  4J8Z A;  2EJ4 A;  1L4S A;  3TGH A;  1PJQ A;  3FIG A;  2JOG A;  4Q7F A;  3LLH A;  4MP0 A;  2V88 A;  3ZU0 A;  2EMB A;  1MGT A;  2VQF E;  2WBS A;  2DXL A;  4JA9 A;  2YEQ A;  1LLM C;  5AE1 A;  3HVQ A;  4WWL A;  1WHQ A;  3VHT B;  1FKA E;  2RPC A;  5KL5 A;  2B9D A;  2DMI A;  2GHF A;  2RSI A;  2EPL X;  1YUI A;  2EOE A;  3CK2 A;  1Z2W A;  2D9H A;  3C4B A;  4OR9 A;  4UT2 A;  2EMI A;  3IWC A;  3GVE A;  3KZZ A;  4WYQ B;  5IXM B;  1A1L A;  4DV1 E;  3ECR A;  2MKN A;  2EPP A;  2MDG A;  1HP1 A;  1ZU1 A;  2IHR 1;  1P47 A;  3N5U A;  2HYO A;  4DMI A;  4H2I A;  2JXP A;  2HJJ A;  4BBY A;  4XPN A;  2LJU A;  1A1F A;  4DKK A;  1II7 A;  3C9F A;  3DW8 C;  4M30 A;  5LL6 R;  2L2K B;  2YTJ A;  3H68 A;  4F0Z A;  2JY9 A;  2EPO A;  1HO5 A;  1N34 E;  2M9A A;  1QFC A;  2H36 X;  2LUP B;  2EPU A;  1OI8 A;  1YYO A;  2J7J A;  1KBP A;  2R17 A;  4IYP C;  4ORC A;  3H62 B;  2L2M A;  1IBL E;  2WZO A;  4LF5 E;  3HQ1 A;  2EMK A;  4NHR A;  4RH8 A;  1J5E E;  1AH5 A;  3BBG A;  2EOI A;  1JK1 A;  3AUZ A;  4DR5 E;  1PJT A;  1HR0 E;  4JI0 E;  2EOQ A;  4LFB E;  4JI4 E;  4ZYG A;  4FBW A;  3E7B A;  4X65 E;  4R8O A;  4TUG A;  1IMU A;  4N4R B;  2AHD A;  4H2G A;  4R03 A;  2EPM X;  2CTD A;  2YSP A;  2NUF A;  2EM0 A;  2R76 A;  2BB8 A;  3QFM A;  3F6G A;  4GZN C;  2WDC A;  4R2R A;  1SR9 A;  3C6M A;  4O43 A;  4WPY A;  3K6Q A;  1I94 E;  4LF8 E;  2NXF A;  4B3M E;  1W24 A;  3D03 A;  4DR6 E;  2EN1 A;  2EMF A;  2N3G A;  1S3M A;  2F8B A;  4X66 E;  4ZYH A;  3RQZ A;  5AE2 A;  2KKN A;  1J26 A; 
#chains in the Genus database with same CATH homology
 4J6O A;  3AV0 A;  2NYL C;  3LL8 A;  3DSC A;  1G5B A;  2ZBM A;  4O4K A;  3K7V C;  4ORB A;  1V73 A;  4ZVZ A;  2Q8U A;  1T71 A;  4I5N C;  3H67 A;  1SU1 A;  2CV9 A;  2ZOA A;  2WDE A;  3EGG A;  5C1V A;  1S70 A;  4V0V A;  4DT2 A;  4UT3 A;  2BQ8 X;  5IOH A;  4JA7 A;  4LTY A;  2BDX A;  4LU9 A;  2Z72 A;  2YVT A;  4ORA A;  3T1I A;  4O24 A;  5INB A;  4FCX A;  1OIE A;  5GTU A;  2IAE C;  3C5W C;  3IVD A;  1T70 A;  2P6B A;  1WAR A;  5JPE A;  3QFN A;  3H66 A;  2Z06 A;  3QFK A;  4UT3 B;  2XMO A;  1Z2X A;  3H60 A;  3PSN A;  3RL5 A;  3H69 A;  4DHL A;  3IVE A;  3TGH A;  1MF8 A;  2IE4 C;  2JOG A;  4Q7F A;  4MP0 A;  3RL3 A;  1UF3 A;  2Z1A A;  4FBQ A;  3ZU0 A;  4DSY A;  3H64 A;  1TCO A;  2DXL A;  4H2F A;  4JA9 A;  2YEQ A;  3HVQ A;  3RL4 A;  3K7W C;  4WWL A;  3IB8 A;  4O5G A;  1WAO 1;  1XZW A;  2NPP C;  1AUI A;  4MOV A;  2QJC A;  4LAC C;  4H1S A;  4NZV A;  3CK2 A;  1HPU A;  4YKE A;  1Z2W A;  2A22 A;  4HD0 A;  4OR9 A;  4UT2 A;  3GVE A;  1UTE A;  3H61 A;  4V0W A;  2GJU A;  2O8A A;  1U32 A;  1JK7 A;  1S95 A;  4I5L C;  3RQZ A;  3V4Y A;  4B2O A;  5J28 A;  1HP1 A;  2HY1 A;  4IL1 A;  2QFR A;  3N5U A;  2HYO A;  4M0V A;  2BCD A;  4H2I A;  1IT6 A;  4XPN A;  3DSD A;  3THN A;  1II7 A;  3C9F A;  3FLO A;  3DW8 C;  4UWQ A;  4FBK A;  3QFO A;  5EQV A;  3H68 A;  4F0Z A;  3KBP A;  4G9J A;  3QG5 C;  3ZTV A;  4ZX2 A;  1HO5 A;  3THO B;  1S3L A;  1QFC A;  2NYM C;  1OI8 A;  4IYP C;  1KBP A;  2R17 A;  2DXN A;  1QHW A;  2WDD A;  3H63 A;  1NNW A;  3H62 B;  3IB7 A;  3P71 C;  4ORC A;  1FJM A;  3ICF A;  4TUI A;  1OID A;  3EGH A;  1USH A;  5F3W A;  3E7A A;  3PSO A;  1XM7 A;  5HPE A;  3AUZ A;  4KKZ A;  4KBP A;  1S3N A;  4FBW A;  3E7B A;  5JPF A;  4TUG A;  2AHD A;  4H1Y P;  2QFP A;  4H2G A;  5JJT A;  5DNY A;  3JYF A;  3QFM A;  4V0X A;  2WDC A;  2DFJ A;  2ZO9 B;  1S8E A;  3FGA C;  4O43 A;  2NXF A;  5B8I A;  3E0J A;  1W24 A;  3D03 A;  2USH A;  2O8G A;  2HYP A;  2IE3 C;  1S3M A;  1M63 A;  4H2B A;  4MOY A;  2WDF A;  2KKN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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