4O43A

Dna double-strand break repair pathway choice is directed by distinct mre11 nuclease activities
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
331
structure length
331
Chain Sequence
IHHHHHHVINLKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGNHDWKGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPDESEALRKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAGYAGIEQGREIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNFPGYVRVVYEEDSGILPDLMGEIDNLVKIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities.
pubmed doi rcsb
molecule tags Dna binding protein/inhibitor
source organism Thermotoga maritima
molecule keywords Exonuclease, putative
total genus 96
structure length 331
sequence length 331
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.160.210 Alpha Beta 2-Layer Sandwich Double Stranded RNA Binding Domain DNA double-strand break repair nuclease 4o43A02
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 4o43A01
1NNWA 1S3NA 3RL4A 3H63A 1Z2XA 4ORAA 3DSCA 1II7A 5EQVA 4Q7FA 2BDXA 3H68A 3IVDA 3K7WC 4H1SA 2HYPA 4HD0A 4UWQA 4O24A 3K7VC 2Z06A 4LTYA 4H2GA 2HYOA 3QFOA 4B2OA 2WDFA 3CK2A 4FCXA 4WWLA 3PSNA 4MOVA 3THNA 5F3WA 4DT2A 3EGGA 3N5UA 3LL8A 1V73A 4IL1A 1UTEA 4O5GA 1U32A 1QHWA 5INBA 1S70A 3H67A 3PSOA 4KBPA 3JYFA 2A22A 3AUZA 1M63A 1USHA 1T70A 1OIDA 4LU9A 4V0XA 2NXFA 4KKZA 2JOGA 3THOB 5DNYA 4UT3A 4YKEA 4UT3B 1TCOA 4V0VA 2QJCA 1FJMA 2IAEC 5HPEA 3E7BA 2NPPC 2NYMC 1SU1A 3P71C 4MOYA 1HO5A 1MF8A 4H2IA 3DSDA 3H66A 2BCDA 1OI8A 1S95A 1XM7A 2DFJA 2R17A 2WDEA 1Z2WA 3IB8A 4F0ZA 2KKNA 1W24A 4TUIA 1UF3A 2GJUA 2BQ8X 3DW8C 3RL5A 4V0WA 4FBKA 1JK7A 1WAO1 3IB7A 3H61A 3HVQA 4J6OA 5JPEA 3ZU0A 2HY1A 5JPFA 1QFCA 2P6BA 3H69A 4IYPC 4NZVA 4MP0A 5JJTA 2YVTA 2Z1AA 3EGHA 2QFRA 2CV9A 5IOHA 3TGHA 4H2BA 4ZX2A 3C9FA 2USHA 3QG5C 3T1IA 1KBPA 4JA9A 4ORCA 1HPUA 4G9JA 2IE4C 3QFMA 3RL3A 4DHLA 5J28A 4TUGA 3E7AA 4O43A 3ZTVA 3C5WC 2Q8UA 3KBPA 2XMOA 3RQZA 2AHDA 3QFNA 2NYLC 1AUIA 1S3MA 2O8GA 4H2FA 2O8AA 4DSYA 4O4KA 1S3LA 1G5BA 5C1VA 4FBQA 4UT2A 1OIEA 3FGAC 4I5LC 4OR9A 2IE3C 2WDCA 4H1YP 1T71A 4I5NC 2Z72A 4LACC 4JA7A 4ORBA 3QFKA 3IVEA 2QFPA 3H60A 3H62B 4XPNA 3V4YA 5GTUA 1IT6A 2WDDA 3ICFA 4FBWA 2ZBMA 3AV0A 4M0VA 1XZWA 1S8EA 3GVEA 1HP1A 3H64A 4ZVZA 5B8IA 1WARA
chains in the Genus database with same CATH superfamily
1UN6B 3KZZA 2YT4A 2UXCE 1J26A 3DSCA 2YTJA 2EOMA 4BC9A 2M7QA 2L8TA 4JI6E 2HJJA 4OOGC 5AASA 2Z06A 4LTYA 2VQFE 2EPMX 3QFOA 4B2OA 2KONA 1P47A 4WWLA 3PSNA 1YPNA 3THNA 4B3RE 1IQOA 1V73A 2YRHA 3T1YE 4O5GA 5LL6R 1A1IA 2JP9A 2ENCA 1QHWA 2I9IA 5INBA 3TQMA 3PSOA 4KBPA 1WHQA 1NCSA 3AUZA 4WXDA 3ZOQB 1I94E 4F9CB 1T70A 3IWBA 4JI5E 4WFTA 1YFHA 4KKZA 2JOGA 3THOB 5IT9C 4ZYHA 5DNYA 4UT3A 2HHHE 4ZYGA 1BB8A 2HGHA 4FBKA 5A6JA 2LO3A 1TF6A 4JI0E 1FJMA 2YTFA 3IWDA 3E7BA 4M30A 2NYMC 3HPSA 5A6BA 1HO5A 4MOYA 1MF8A 1WRJA 1X49A 1FJGE 1PJTA 2EM7A 1QNTA 5B8IA 2F4VE 2NA2A 3J80C 1Z1BA 2LUQA 4AQYE 1UF3A 2V86A 4DV7E 1YYOA 2GJUA 2B3TB 3KWRA 1IBME 1WJPA 4DV4E 4MLQA 4V0WA 1BBOA 4KWYA 1JK7A 2E72A 3IWCA 3JTZA 2EMYA 5IXMB 2LT7A 2DB2A 3IB7A 3OMLA 2HY1A 5KL5A 4IS1C 1A1LA 5LMUE 2UXBE 5JPFA 2YTGA 4JI4E 4MP0A 4WSGA 2GHFA 3F6GA 1X3CA 2EOOA 4DMIA 1EH8A 2EN7A 5LLQA 1IBKE 1A1FA 1KBPA 4JA9A 3EPLA 2RSMA 4KZSA 4JV5E 2EPUA 3FIGA 2LRSA 4L8NA 2LVHA 1XMOE 2XMOA 2JOBA 1YZ9A 2G7HA 1B69A 4X62E 2VQEE 2RS7A 2NYLC 3VK6A 1S3MA 1PJQA 3J81C 4RH8A 2O8AA 1L4SA 5KL2A 4FBQA 3FGAC 4I5LC 2YTDA 1T4NA 3C6KA 2UU9E 4H1YP 2YTPA 2M1SA 1XNQE 4I5NC 2Z72A 5KL6A 4LACC 5CFFE 2EN8A 1NEIA 2DRPA 1X5WA 3H62B 4XPNA 2V89A 2CTDA 3VYYA 4B3TE 2ZM6E 1ZAAC 4R2PA 2YRKA 4DR1E 2YU8A 4WYQB 1S8EA 1EH7A 2MDGA 4ZVZA 1T4LB 2EM6A 1QU6A 1WARA 3H63A 2EZ6A 3EPHA 1TN9A 1II7A 2RS6A 3IVDA 1YUJA 1N3GA 3VHTB 1XNRE 2PRTA 4HD0A 2WBSA 4UWQA 2EOZA 2DXLA 3K6QA 2HYOA 5A6AA 1LLMC 4I8OA 1X47A 4MOVA 4NXME 2J7JA 2DMIA 2EOSA 2NUEA 1UBDC 2EPAA 5AC5A 2IHR1 3OTOE 2EPCA 2JYAA 1GQEA 2CSHA 1UTEA 1ZBQA 2EOJA 2L92A 1YSAC 2EOIA 2A22A 1A1HA 2LMZA 1N34E 2YTNA 4LU9A 2JXPA 1JK1A 4F54A 2NXFA 2M9AA 2GLIA 1BBGA 4X64E 1T4OA 2JPAA 2EOYA 2EPOA 2NABA 3H09A 5AC4A 5HPEA 2UXDE 1N36E 1MGTA 4MLVA 4R2DA 2LUPB 1GZ6A 4JI3E 4BC7A 3DSDA 2LJUA 4N4RB 3H66A 2LV2A 1OI8A 5A6BD 1S95A 2UUAE 2R17A 2WDEA 3E0JA 4JI7E 4F0ZA 1W24A 2LCEA 4TUIA 2N3GA 3P1XA 2BQ8X 4Q35B 3DW8C 2EPPA 1WXRA 3RL5A 2EM0A 4X65E 2V8QB 3ZU0A 4R2QA 2MDRA 2YU5A 2YPNA 4R2EA 2DXNA 4M9VC 1QFCA 2P6BA 3H69A 5IV8B 2NUGA 4R2RA 4GEQB 3VYXA 1N33E 2FGGA 2EPNA 3TGHA 4H2BA 4ZX2A 5A2QC 3HXLA 2USHA 3T1IA 2L2KB 2EOHA 2MKNA 2EM3A 4F9AB 2EL6A 2EMFA 5KL3A 4DR7E 3JU0A 4ORCA 4G9JA 4F6MA 3BF2A 4DUYE 4O43A 2ZOAA 2CPNA 2EMAA 5A6KA 2EMHA 4OX9E 4DV2E 2ENHA 3DJWA 4X9JA 1IMUA 3RQZA 2LTSA 2AHDA 2WZOA 2EM2A 2EMKA 1STUA 4F6NA 2O8GA 2WCC3 1S3LA 1G5BA 2EQ0A 2A25A 4R03A 2EMCA 2JVAA 4FK5C 2EPXA 2K4VA 2L3JA 2DGCA 3QFKA 1JK2A 2E1MA 4LF8E 4DKKA 1AAYA 3V4YA 2ODRC 4R2CA 4FBWA 1DQ3A 2BBGA 2VE7C 4B3SE 2ZBMA 1IBLE 3ADGA 3AV0A 4M0VA 4RHBB 4DR3E 4LF6E 4WXCA 3GVEA 2EM9A 5IWAE 4WX9A 1FKAE 2YTEA 1NNWA 2EN4A 2VF1A 4DV6E 1EKZA 5FLXC 3EPKA 4DV5E 5EQVA 2BDXA 3H68A 3K7WC 3UK3C 2EPKX 3J7AG 3EPJA 4WPYA 2HYPA 1T39A 2L3CA 4LF7E 4O24A 3K7VC 1X6FA 2N3HA 4K0KE 4LF4E 2WBTA 3CK2A 4FCXA 2YEQA 1HR0E 2DMYA 2L6MA 3LL8A 3RMPA 2KHXA 4IL1A 2FTXB 4WSPA 3F6HA 1YYKA 1M63A 3DF6A 2RPCA 3LMLA 1ZU1A 1DI2A 5ADZA 4UT3B 2L33A 2EL4A 4BHCA 2JR1A 2MKDA 1IQSA 2VRDA 2QJCA 3MHSC 2IAEC 2ZO9B 3D03A 2NPPC 3P71C 3BBGA 1EH6A 2HC5A 2ENAA 2UUBE 4HTGA 2EWLA 1A1GA 1XM7A 2CT1A 2DFJA 2EP3A 2KKNA 4BMJA 2L2NA 3M99B 2R76A 2FV4B 2UUCE 5AE2A 4F2JC 1WAO1 4F9BB 3H61A 2EN6A 3HVQA 4Q28A 1PJSA 2H36X 4JI1E 2ELZA 2RSIA 1YUIA 4IYPC 5JJTA 2ADRA 2JOXA 2YVTA 2Z1AA 3EGHA 1AH5A 2CV9A 3T1HE 2QFRA 5IOHA 3EQ1A 1UILA 2L2MA 4JI8E 4IJDA 5KL4A 4DV3E 3RL3A 5AE3A 4TUGA 2YRMA 3ZTVA 1UHZA 3C5WC 1XMQE 4DR4E 2B9DA 3C4TA 3QFNA 2YTIA 4NXNE 1MEYC 1AUIA 4H2FA 4P7DA 4O4KA 4DV0E 4YHHE 2F8BA 3KZYA 4UT2A 2EORA 2E5LE 2IE3C 3FLOA 3ADJA 5T6JA 4LFBE 1T71A 5KL7A 4JA7A 3MSWA 4ORBA 3LLHA 3ADIA 2I13A 3H60A 2V87A 2EN3A 4YY3E 5TSEA 1ZBTA 1TF3A 1SFEA 4GKKE 2RQLA 1XZWA 2K7IA 2EM8A 4L5NC 1HP1A 4GZNC 3H64A 2ELYA 2EQ1A 2EOQA 3C6MA 1S3NA 3RL4A 1X48A 4X66E 4DR2E 1Z2XA 4ORAA 1X6HA 4Q7FA 4H1SA 2EPRA 1SR9A 2GPIA 2JY9A 2NUFA 4JYAE 2YTOA 4H2GA 1PKPA 3C4BA 2B7TA 3L00A 2WDFA 1GTKA 2KOUA 2BB8A 3JAMC 5F3WA 1O0WA 1T38A 2JWOA 4DT2A 2N8XA 1HNXE 2V83A 2YTQA 3J7Yp 4DV1E 5A69A 3EGGA 3N5UA 1U32A 2EM5A 1S70A 2EN2A 1J5EE 4BBYA 3H67A 3JYFA 1USHA 2D9HA 4NHRA 1OIDA 4R2SA 4DR5E 4KHPE 2EL5A 4V0XA 4LF5E 4YKEA 1A1JA 2LE2A 1TCOA 2LBSB 4V0VA 3HPZA 2LJHA 1RMDA 1HNZE 4ZYDA 1SU1A 2EJ4A 4H2IA 2EQ3A 4P78A 4BS9A 2WBUA 5BR8E 2BCDA 5LMNE 2DIXA 1X6EA 3HTXA 3IB8A 2EOXA 2MC6A 1Z2WA 2B7VA 1G2DC 2DSYA 2YSOA 2YSPA 1KJKA 4ZYEA 2RTXA 2YZTA 4LF9E 4J6OA 5JPEA 4R8OA 2YWQA 2MC5A 3ADLA 4GKJE 2M4IA 1F2IG 2EPLX 2EMXA 4NZVA 3BIDA 2EM4A 4B3ME 2EOFA 2EE8A 3C9FA 3QG5C 1HNWE 2EMZA 4R2AA 1HPUA 1ZR9A 2IE4C 3QFMA 4DHLA 4J8ZA 1RC7A 5J28A 2DLKA 4DUZE 3E7AA 2R1FA 4JI2E 3KBPA 2Q8UA 2V88A 4LFAE 1KYQA 2EMGA 4HEIA 2EMIA 2EPZA 1WHNA 1YYWA 4DSYA 2LTRA 3MHHC 1DGCA 2EMBA 2ODRD 5C1VA 4X8WA 1OIEA 4OR9A 2DLQA 1A1KA 2WDCA 1PDAA 3BGHA 4BCAA 5AE1A 1G2FC 2EN1A 2V85A 2EMLA 3IVEA 2QFPA 4M2ZA 4LFCE 4BHBA 5GTUA 1IT6A 2WDDA 3ICFA 1N32E 3ECRA 4DR6E 1RQ0A 3HQ1A 2EMWA 2EOEA
chains in the Genus database with same CATH topology
1NNWA 1S3NA 3RL4A 3H63A 1Z2XA 3DSCA 4ORAA 1II7A 5EQVA 4Q7FA 2BDXA 3H68A 3IVDA 3K7WC 4H1SA 4HD0A 2HYPA 4UWQA 4O24A 3K7VC 2DXLA 2Z06A 4H2GA 4LTYA 2HYOA 3QFOA 4B2OA 2WDFA 3CK2A 4FCXA 4WWLA 2YEQA 3PSNA 4MOVA 3THNA 5F3WA 4DT2A 3EGGA 3N5UA 3LL8A 1V73A 4IL1A 1UTEA 4O5GA 1U32A 1QHWA 5INBA 1S70A 3H67A 3PSOA 4KBPA 3JYFA 2A22A 3AUZA 1M63A 1USHA 1T70A 1OIDA 4LU9A 4V0XA 2NXFA 4KKZA 2JOGA 3THOB 5DNYA 4UT3A 4YKEA 4UT3B 1TCOA 4V0VA 2QJCA 1FJMA 2IAEC 5HPEA 2ZO9B 3D03A 3E7BA 2NPPC 2NYMC 1SU1A 3P71C 4MOYA 1HO5A 1MF8A 4H2IA 3DSDA 3H66A 2BCDA 1OI8A 1S95A 1XM7A 2DFJA 2R17A 2WDEA 1Z2WA 3E0JA 3IB8A 4F0ZA 2KKNA 1W24A 4TUIA 1UF3A 2GJUA 2BQ8X 3DW8C 3RL5A 4V0WA 4FBKA 1JK7A 1WAO1 3IB7A 3H61A 3HVQA 4J6OA 5JPEA 3ZU0A 2HY1A 5JPFA 2DXNA 1QFCA 2P6BA 3H69A 4IYPC 4NZVA 4MP0A 5JJTA 2YVTA 2Z1AA 3EGHA 2QFRA 2CV9A 5IOHA 3TGHA 4H2BA 4ZX2A 3C9FA 2USHA 3QG5C 3T1IA 1KBPA 4JA9A 4ORCA 1HPUA 4G9JA 2IE4C 3QFMA 3RL3A 4DHLA 5J28A 4TUGA 3E7AA 4O43A 2ZOAA 3ZTVA 3C5WC 2Q8UA 3KBPA 2XMOA 3RQZA 2AHDA 3QFNA 2NYLC 1AUIA 1S3MA 2O8GA 4H2FA 2O8AA 4DSYA 4O4KA 1S3LA 1G5BA 5C1VA 4FBQA 4UT2A 1OIEA 3FGAC 4I5LC 4OR9A 2IE3C 2WDCA 3FLOA 4H1YP 1T71A 4I5NC 2Z72A 4LACC 4JA7A 4ORBA 3QFKA 3IVEA 2QFPA 3H60A 3H62B 4XPNA 3V4YA 5GTUA 1IT6A 2WDDA 3ICFA 4FBWA 2ZBMA 3AV0A 4M0VA 1XZWA 1S8EA 3GVEA 1HP1A 3H64A 4ZVZA 5B8IA 1WARA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NNW A;  1S3N A;  3RL4 A;  3H63 A;  1Z2X A;  4ORA A;  3DSC A;  1II7 A;  5EQV A;  4Q7F A;  2BDX A;  3H68 A;  3IVD A;  3K7W C;  4H1S A;  2HYP A;  4HD0 A;  4UWQ A;  4O24 A;  3K7V C;  2Z06 A;  4LTY A;  4H2G A;  2HYO A;  3QFO A;  4B2O A;  2WDF A;  3CK2 A;  4FCX A;  4WWL A;  3PSN A;  4MOV A;  3THN A;  5F3W A;  4DT2 A;  3EGG A;  3N5U A;  3LL8 A;  1V73 A;  4IL1 A;  1UTE A;  4O5G A;  1U32 A;  1QHW A;  5INB A;  1S70 A;  3H67 A;  3PSO A;  4KBP A;  3JYF A;  2A22 A;  3AUZ A;  1M63 A;  1USH A;  1T70 A;  1OID A;  4LU9 A;  4V0X A;  2NXF A;  4KKZ A;  2JOG A;  3THO B;  5DNY A;  4UT3 A;  4YKE A;  4UT3 B;  1TCO A;  4V0V A;  2QJC A;  1FJM A;  2IAE C;  5HPE A;  3E7B A;  2NPP C;  2NYM C;  1SU1 A;  3P71 C;  4MOY A;  1HO5 A;  1MF8 A;  4H2I A;  3DSD A;  3H66 A;  2BCD A;  1OI8 A;  1S95 A;  1XM7 A;  2DFJ A;  2R17 A;  2WDE A;  1Z2W A;  3IB8 A;  4F0Z A;  2KKN A;  1W24 A;  4TUI A;  1UF3 A;  2GJU A;  2BQ8 X;  3DW8 C;  3RL5 A;  4V0W A;  4FBK A;  1JK7 A;  1WAO 1;  3IB7 A;  3H61 A;  3HVQ A;  4J6O A;  5JPE A;  3ZU0 A;  2HY1 A;  5JPF A;  1QFC A;  2P6B A;  3H69 A;  4IYP C;  4NZV A;  4MP0 A;  5JJT A;  2YVT A;  2Z1A A;  3EGH A;  2QFR A;  2CV9 A;  5IOH A;  3TGH A;  4H2B A;  4ZX2 A;  3C9F A;  2USH A;  3QG5 C;  3T1I A;  1KBP A;  4JA9 A;  4ORC A;  1HPU A;  4G9J A;  2IE4 C;  3QFM A;  3RL3 A;  4DHL A;  5J28 A;  4TUG A;  3E7A A;  4O43 A;  3ZTV A;  3C5W C;  2Q8U A;  3KBP A;  2XMO A;  3RQZ A;  2AHD A;  3QFN A;  2NYL C;  1AUI A;  1S3M A;  2O8G A;  4H2F A;  2O8A A;  4DSY A;  4O4K A;  1S3L A;  1G5B A;  5C1V A;  4FBQ A;  4UT2 A;  1OIE A;  3FGA C;  4I5L C;  4OR9 A;  2IE3 C;  2WDC A;  4H1Y P;  1T71 A;  4I5N C;  2Z72 A;  4LAC C;  4JA7 A;  4ORB A;  3QFK A;  3IVE A;  2QFP A;  3H60 A;  3H62 B;  4XPN A;  3V4Y A;  5GTU A;  1IT6 A;  2WDD A;  3ICF A;  4FBW A;  2ZBM A;  3AV0 A;  4M0V A;  1XZW A;  1S8E A;  3GVE A;  1HP1 A;  3H64 A;  4ZVZ A;  5B8I A;  1WAR A; 
#chains in the Genus database with same CATH topology
 1UN6 B;  3KZZ A;  2YT4 A;  2UXC E;  1J26 A;  3DSC A;  2YTJ A;  2EOM A;  4BC9 A;  2M7Q A;  2L8T A;  4JI6 E;  2HJJ A;  4OOG C;  5AAS A;  2Z06 A;  4LTY A;  2VQF E;  2EPM X;  3QFO A;  4B2O A;  2KON A;  1P47 A;  4WWL A;  3PSN A;  1YPN A;  3THN A;  4B3R E;  1IQO A;  1V73 A;  2YRH A;  3T1Y E;  4O5G A;  5LL6 R;  1A1I A;  2JP9 A;  2ENC A;  1QHW A;  2I9I A;  5INB A;  3TQM A;  3PSO A;  4KBP A;  1WHQ A;  1NCS A;  3AUZ A;  4WXD A;  3ZOQ B;  1I94 E;  4F9C B;  1T70 A;  3IWB A;  4JI5 E;  4WFT A;  1YFH A;  4KKZ A;  2JOG A;  3THO B;  5IT9 C;  4ZYH A;  5DNY A;  4UT3 A;  2HHH E;  4ZYG A;  1BB8 A;  2HGH A;  4FBK A;  5A6J A;  2LO3 A;  1TF6 A;  4JI0 E;  1FJM A;  2YTF A;  3IWD A;  3E7B A;  4M30 A;  2NYM C;  3HPS A;  5A6B A;  1HO5 A;  4MOY A;  1MF8 A;  1WRJ A;  1X49 A;  1FJG E;  1PJT A;  2EM7 A;  1QNT A;  5B8I A;  2F4V E;  2NA2 A;  3J80 C;  1Z1B A;  2LUQ A;  4AQY E;  1UF3 A;  2V86 A;  4DV7 E;  1YYO A;  2GJU A;  2B3T B;  3KWR A;  1IBM E;  1WJP A;  4DV4 E;  4MLQ A;  4V0W A;  1BBO A;  4KWY A;  1JK7 A;  2E72 A;  3IWC A;  3JTZ A;  2EMY A;  5IXM B;  2LT7 A;  2DB2 A;  3IB7 A;  3OML A;  2HY1 A;  5KL5 A;  4IS1 C;  1A1L A;  5LMU E;  2UXB E;  5JPF A;  2YTG A;  4JI4 E;  4MP0 A;  4WSG A;  2GHF A;  3F6G A;  1X3C A;  2EOO A;  4DMI A;  1EH8 A;  2EN7 A;  5LLQ A;  1IBK E;  1A1F A;  1KBP A;  4JA9 A;  3EPL A;  2RSM A;  4KZS A;  4JV5 E;  2EPU A;  3FIG A;  2LRS A;  4L8N A;  2LVH A;  1XMO E;  2XMO A;  2JOB A;  1YZ9 A;  2G7H A;  1B69 A;  4X62 E;  2VQE E;  2RS7 A;  2NYL C;  3VK6 A;  1S3M A;  1PJQ A;  3J81 C;  4RH8 A;  2O8A A;  1L4S A;  5KL2 A;  4FBQ A;  3FGA C;  4I5L C;  2YTD A;  1T4N A;  3C6K A;  2UU9 E;  4H1Y P;  2YTP A;  2M1S A;  1XNQ E;  4I5N C;  2Z72 A;  5KL6 A;  4LAC C;  5CFF E;  2EN8 A;  1NEI A;  2DRP A;  1X5W A;  3H62 B;  4XPN A;  2V89 A;  2CTD A;  3VYY A;  4B3T E;  2ZM6 E;  1ZAA C;  4R2P A;  2YRK A;  4DR1 E;  2YU8 A;  4WYQ B;  1S8E A;  1EH7 A;  2MDG A;  4ZVZ A;  1T4L B;  2EM6 A;  1QU6 A;  1WAR A;  3H63 A;  2EZ6 A;  3EPH A;  1TN9 A;  1II7 A;  2RS6 A;  3IVD A;  1YUJ A;  1N3G A;  3VHT B;  1XNR E;  2PRT A;  4HD0 A;  2WBS A;  4UWQ A;  2EOZ A;  2DXL A;  3K6Q A;  2HYO A;  5A6A A;  1LLM C;  4I8O A;  1X47 A;  4MOV A;  4NXM E;  2J7J A;  2DMI A;  2EOS A;  2NUE A;  1UBD C;  2EPA A;  5AC5 A;  2IHR 1;  3OTO E;  2EPC A;  2JYA A;  1GQE A;  2CSH A;  1UTE A;  1ZBQ A;  2EOJ A;  2L92 A;  1YSA C;  2EOI A;  2A22 A;  1A1H A;  2LMZ A;  1N34 E;  2YTN A;  4LU9 A;  2JXP A;  1JK1 A;  4F54 A;  2NXF A;  2M9A A;  2GLI A;  1BBG A;  4X64 E;  1T4O A;  2JPA A;  2EOY A;  2EPO A;  2NAB A;  3H09 A;  5AC4 A;  5HPE A;  2UXD E;  1N36 E;  1MGT A;  4MLV A;  4R2D A;  2LUP B;  1GZ6 A;  4JI3 E;  4BC7 A;  3DSD A;  2LJU A;  4N4R B;  3H66 A;  2LV2 A;  1OI8 A;  5A6B D;  1S95 A;  2UUA E;  2R17 A;  2WDE A;  3E0J A;  4JI7 E;  4F0Z A;  1W24 A;  2LCE A;  4TUI A;  2N3G A;  3P1X A;  2BQ8 X;  4Q35 B;  3DW8 C;  2EPP A;  1WXR A;  3RL5 A;  2EM0 A;  4X65 E;  2V8Q B;  3ZU0 A;  4R2Q A;  2MDR A;  2YU5 A;  2YPN A;  4R2E A;  2DXN A;  4M9V C;  1QFC A;  2P6B A;  3H69 A;  5IV8 B;  2NUG A;  4R2R A;  4GEQ B;  3VYX A;  1N33 E;  2FGG A;  2EPN A;  3TGH A;  4H2B A;  4ZX2 A;  5A2Q C;  3HXL A;  2USH A;  3T1I A;  2L2K B;  2EOH A;  2MKN A;  2EM3 A;  4F9A B;  2EL6 A;  2EMF A;  5KL3 A;  4DR7 E;  3JU0 A;  4ORC A;  4G9J A;  4F6M A;  3BF2 A;  4DUY E;  4O43 A;  2ZOA A;  2CPN A;  2EMA A;  5A6K A;  2EMH A;  4OX9 E;  4DV2 E;  2ENH A;  3DJW A;  4X9J A;  1IMU A;  3RQZ A;  2LTS A;  2AHD A;  2WZO A;  2EM2 A;  2EMK A;  1STU A;  4F6N A;  2O8G A;  2WCC 3;  1S3L A;  1G5B A;  2EQ0 A;  2A25 A;  4R03 A;  2EMC A;  2JVA A;  4FK5 C;  2EPX A;  2K4V A;  2L3J A;  2DGC A;  3QFK A;  1JK2 A;  2E1M A;  4LF8 E;  4DKK A;  1AAY A;  3V4Y A;  2ODR C;  4R2C A;  4FBW A;  1DQ3 A;  2BBG A;  2VE7 C;  4B3S E;  2ZBM A;  1IBL E;  3ADG A;  3AV0 A;  4M0V A;  4RHB B;  4DR3 E;  4LF6 E;  4WXC A;  3GVE A;  2EM9 A;  5IWA E;  4WX9 A;  1FKA E;  2YTE A;  1NNW A;  2EN4 A;  2VF1 A;  4DV6 E;  1EKZ A;  5FLX C;  3EPK A;  4DV5 E;  5EQV A;  2BDX A;  3H68 A;  3K7W C;  3UK3 C;  2EPK X;  3J7A G;  3EPJ A;  4WPY A;  2HYP A;  1T39 A;  2L3C A;  4LF7 E;  4O24 A;  3K7V C;  1X6F A;  2N3H A;  4K0K E;  4LF4 E;  2WBT A;  3CK2 A;  4FCX A;  2YEQ A;  1HR0 E;  2DMY A;  2L6M A;  3LL8 A;  3RMP A;  2KHX A;  4IL1 A;  2FTX B;  4WSP A;  3F6H A;  1YYK A;  1M63 A;  3DF6 A;  2RPC A;  3LML A;  1ZU1 A;  1DI2 A;  5ADZ A;  4UT3 B;  2L33 A;  2EL4 A;  4BHC A;  2JR1 A;  2MKD A;  1IQS A;  2VRD A;  2QJC A;  3MHS C;  2IAE C;  2ZO9 B;  3D03 A;  2NPP C;  3P71 C;  3BBG A;  1EH6 A;  2HC5 A;  2ENA A;  2UUB E;  4HTG A;  2EWL A;  1A1G A;  1XM7 A;  2CT1 A;  2DFJ A;  2EP3 A;  2KKN A;  4BMJ A;  2L2N A;  3M99 B;  2R76 A;  2FV4 B;  2UUC E;  5AE2 A;  4F2J C;  1WAO 1;  4F9B B;  3H61 A;  2EN6 A;  3HVQ A;  4Q28 A;  1PJS A;  2H36 X;  4JI1 E;  2ELZ A;  2RSI A;  1YUI A;  4IYP C;  5JJT A;  2ADR A;  2JOX A;  2YVT A;  2Z1A A;  3EGH A;  1AH5 A;  2CV9 A;  3T1H E;  2QFR A;  5IOH A;  3EQ1 A;  1UIL A;  2L2M A;  4JI8 E;  4IJD A;  5KL4 A;  4DV3 E;  3RL3 A;  5AE3 A;  4TUG A;  2YRM A;  3ZTV A;  1UHZ A;  3C5W C;  1XMQ E;  4DR4 E;  2B9D A;  3C4T A;  3QFN A;  2YTI A;  4NXN E;  1MEY C;  1AUI A;  4H2F A;  4P7D A;  4O4K A;  4DV0 E;  4YHH E;  2F8B A;  3KZY A;  4UT2 A;  2EOR A;  2E5L E;  2IE3 C;  3FLO A;  3ADJ A;  5T6J A;  4LFB E;  1T71 A;  5KL7 A;  4JA7 A;  3MSW A;  4ORB A;  3LLH A;  3ADI A;  2I13 A;  3H60 A;  2V87 A;  2EN3 A;  4YY3 E;  5TSE A;  1ZBT A;  1TF3 A;  1SFE A;  4GKK E;  2RQL A;  1XZW A;  2K7I A;  2EM8 A;  4L5N C;  1HP1 A;  4GZN C;  3H64 A;  2ELY A;  2EQ1 A;  2EOQ A;  3C6M A;  1S3N A;  3RL4 A;  1X48 A;  4X66 E;  4DR2 E;  1Z2X A;  4ORA A;  1X6H A;  4Q7F A;  4H1S A;  2EPR A;  1SR9 A;  2GPI A;  2JY9 A;  2NUF A;  4JYA E;  2YTO A;  4H2G A;  1PKP A;  3C4B A;  2B7T A;  3L00 A;  2WDF A;  1GTK A;  2KOU A;  2BB8 A;  3JAM C;  5F3W A;  1O0W A;  1T38 A;  2JWO A;  4DT2 A;  2N8X A;  1HNX E;  2V83 A;  2YTQ A;  3J7Y p;  4DV1 E;  5A69 A;  3EGG A;  3N5U A;  1U32 A;  2EM5 A;  1S70 A;  2EN2 A;  1J5E E;  4BBY A;  3H67 A;  3JYF A;  1USH A;  2D9H A;  4NHR A;  1OID A;  4R2S A;  4DR5 E;  4KHP E;  2EL5 A;  4V0X A;  4LF5 E;  4YKE A;  1A1J A;  2LE2 A;  1TCO A;  2LBS B;  4V0V A;  3HPZ A;  2LJH A;  1RMD A;  1HNZ E;  4ZYD A;  1SU1 A;  2EJ4 A;  4H2I A;  2EQ3 A;  4P78 A;  4BS9 A;  2WBU A;  5BR8 E;  2BCD A;  5LMN E;  2DIX A;  1X6E A;  3HTX A;  3IB8 A;  2EOX A;  2MC6 A;  1Z2W A;  2B7V A;  1G2D C;  2DSY A;  2YSO A;  2YSP A;  1KJK A;  4ZYE A;  2RTX A;  2YZT A;  4LF9 E;  4J6O A;  5JPE A;  4R8O A;  2YWQ A;  2MC5 A;  3ADL A;  4GKJ E;  2M4I A;  1F2I G;  2EPL X;  2EMX A;  4NZV A;  3BID A;  2EM4 A;  4B3M E;  2EOF A;  2EE8 A;  3C9F A;  3QG5 C;  1HNW E;  2EMZ A;  4R2A A;  1HPU A;  1ZR9 A;  2IE4 C;  3QFM A;  4DHL A;  4J8Z A;  1RC7 A;  5J28 A;  2DLK A;  4DUZ E;  3E7A A;  2R1F A;  4JI2 E;  3KBP A;  2Q8U A;  2V88 A;  4LFA E;  1KYQ A;  2EMG A;  4HEI A;  2EMI A;  2EPZ A;  1WHN A;  1YYW A;  4DSY A;  2LTR A;  3MHH C;  1DGC A;  2EMB A;  2ODR D;  5C1V A;  4X8W A;  1OIE A;  4OR9 A;  2DLQ A;  1A1K A;  2WDC A;  1PDA A;  3BGH A;  4BCA A;  5AE1 A;  1G2F C;  2EN1 A;  2V85 A;  2EML A;  3IVE A;  2QFP A;  4M2Z A;  4LFC E;  4BHB A;  5GTU A;  1IT6 A;  2WDD A;  3ICF A;  1N32 E;  3ECR A;  4DR6 E;  1RQ0 A;  3HQ1 A;  2EMW A;  2EOE A; 
#chains in the Genus database with same CATH homology
 1NNW A;  1S3N A;  3RL4 A;  3H63 A;  1Z2X A;  3DSC A;  4ORA A;  1II7 A;  5EQV A;  4Q7F A;  2BDX A;  3H68 A;  3IVD A;  3K7W C;  4H1S A;  4HD0 A;  2HYP A;  4UWQ A;  4O24 A;  3K7V C;  2DXL A;  2Z06 A;  4H2G A;  4LTY A;  2HYO A;  3QFO A;  4B2O A;  2WDF A;  3CK2 A;  4FCX A;  4WWL A;  2YEQ A;  3PSN A;  4MOV A;  3THN A;  5F3W A;  4DT2 A;  3EGG A;  3N5U A;  3LL8 A;  1V73 A;  4IL1 A;  1UTE A;  4O5G A;  1U32 A;  1QHW A;  5INB A;  1S70 A;  3H67 A;  3PSO A;  4KBP A;  3JYF A;  2A22 A;  3AUZ A;  1M63 A;  1USH A;  1T70 A;  1OID A;  4LU9 A;  4V0X A;  2NXF A;  4KKZ A;  2JOG A;  3THO B;  5DNY A;  4UT3 A;  4YKE A;  4UT3 B;  1TCO A;  4V0V A;  2QJC A;  1FJM A;  2IAE C;  5HPE A;  2ZO9 B;  3D03 A;  3E7B A;  2NPP C;  2NYM C;  1SU1 A;  3P71 C;  4MOY A;  1HO5 A;  1MF8 A;  4H2I A;  3DSD A;  3H66 A;  2BCD A;  1OI8 A;  1S95 A;  1XM7 A;  2DFJ A;  2R17 A;  2WDE A;  1Z2W A;  3E0J A;  3IB8 A;  4F0Z A;  2KKN A;  1W24 A;  4TUI A;  1UF3 A;  2GJU A;  2BQ8 X;  3DW8 C;  3RL5 A;  4V0W A;  4FBK A;  1JK7 A;  1WAO 1;  3IB7 A;  3H61 A;  3HVQ A;  4J6O A;  5JPE A;  3ZU0 A;  2HY1 A;  5JPF A;  2DXN A;  1QFC A;  2P6B A;  3H69 A;  4IYP C;  4NZV A;  4MP0 A;  5JJT A;  2YVT A;  2Z1A A;  3EGH A;  2QFR A;  2CV9 A;  5IOH A;  3TGH A;  4H2B A;  4ZX2 A;  3C9F A;  2USH A;  3QG5 C;  3T1I A;  1KBP A;  4JA9 A;  4ORC A;  1HPU A;  4G9J A;  2IE4 C;  3QFM A;  3RL3 A;  4DHL A;  5J28 A;  4TUG A;  3E7A A;  4O43 A;  2ZOA A;  3ZTV A;  3C5W C;  2Q8U A;  3KBP A;  2XMO A;  3RQZ A;  2AHD A;  3QFN A;  2NYL C;  1AUI A;  1S3M A;  2O8G A;  4H2F A;  2O8A A;  4DSY A;  4O4K A;  1S3L A;  1G5B A;  5C1V A;  4FBQ A;  4UT2 A;  1OIE A;  3FGA C;  4I5L C;  4OR9 A;  2IE3 C;  2WDC A;  3FLO A;  4H1Y P;  1T71 A;  4I5N C;  2Z72 A;  4LAC C;  4JA7 A;  4ORB A;  3QFK A;  3IVE A;  2QFP A;  3H60 A;  3H62 B;  4XPN A;  3V4Y A;  5GTU A;  1IT6 A;  2WDD A;  3ICF A;  4FBW A;  2ZBM A;  3AV0 A;  4M0V A;  1XZW A;  1S8E A;  3GVE A;  1HP1 A;  3H64 A;  4ZVZ A;  5B8I A;  1WAR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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