4O4KA

Dna double-strand break repair pathway choice is directed by distinct mre11 nuclease activities
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
331
structure length
331
Chain Sequence
IHHHHHHVINLKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGNHDWKGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPDESEALRKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAGYAGIEQGREIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNFPGYVRVVYEEDSGILPDLMGEIDNLVKIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities.
pubmed doi rcsb
molecule tags Dna binding protein/inhibitor
source organism Thermotoga maritima
molecule keywords Exonuclease, putative
total genus 103
structure length 331
sequence length 331
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.160.210 Alpha Beta 2-Layer Sandwich Double Stranded RNA Binding Domain DNA double-strand break repair nuclease 4o4kA02
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 4o4kA01
4XPNA 4KBPA 1OI8A 2KKNA 3IVDA 4V0XA 4B2OA 1II7A 2IE4C 3EGGA 4FBQA 3RQZA 4TUGA 5F3WA 3K7VC 2NYLC 1QFCA 3ZU0A 2XMOA 1M63A 3FGAC 3JYFA 3P71C 4YKEA 2BQ8X 4ORAA 3RL5A 1UF3A 3DW8C 4IYPC 4O24A 1HP1A 2USHA 3C5WC 2QFPA 4Q7FA 3RL3A 3QFNA 4H1YP 4HD0A 1OIDA 1WAO1 4I5NC 4LTYA 3TGHA 1G5BA 3QG5C 4MOVA 1Z2XA 4ZX2A 5JJTA 4UT3A 3H63A 3THNA 2HYPA 4FCXA 4H2IA 4DT2A 1S8EA 4DSYA 1S3MA 5J28A 4FBWA 2P6BA 4UT2A 1TCOA 3V4YA 3KBPA 1SU1A 4V0WA 4H1SA 2IAEC 2O8GA 3GVEA 3QFOA 1HO5A 1NNWA 1V73A 2ZBMA 3CK2A 4ORCA 2WDEA 1S70A 3AUZA 4KKZA 2Z72A 2QFRA 2WDFA 4DHLA 3H67A 4I5LC 1Z2WA 3N5UA 4IL1A 1OIEA 4H2BA 2O8AA 4MP0A 1XZWA 4H2GA 3RL4A 2BCDA 3H62B 3DSDA 3H68A 4UT3B 3T1IA 2Z06A 1QHWA 2WDDA 2HY1A 4O43A 1FJMA 3THOB 4ORBA 4LU9A 2Q8UA 3H61A 4FBKA 1U32A 1S3LA 2YVTA 2IE3C 2CV9A 2GJUA 3QFKA 3ICFA 1IT6A 4UWQA 5C1VA 4NZVA 2QJCA 4G9JA 4MOYA 4J6OA 2A22A 3ZTVA 1HPUA 2NPPC 5DNYA 4V0VA 3E7BA 3H64A 4LACC 2JOGA 4O5GA 5JPFA 4JA7A 1T70A 4TUIA 3DSCA 1USHA 1XM7A 5JPEA 5GTUA 1AUIA 3K7WC 3H69A 5IOHA 4WWLA 4O4KA 3E7AA 4OR9A 1UTEA 1MF8A 1S3NA 3H66A 2NYMC 2Z1AA 4ZVZA 3IB7A 3C9FA 1JK7A 3IVEA 1T71A 3IB8A 4M0VA 2NXFA 3PSNA 1WARA 5B8IA 5HPEA 4F0ZA 3EGHA 2BDXA 2DFJA 5EQVA 4H2FA 3H60A 1KBPA 3HVQA 5INBA 3AV0A 2AHDA 3LL8A 3PSOA 2WDCA 2R17A 3QFMA 4JA9A 1S95A 1W24A 2HYOA
chains in the Genus database with same CATH superfamily
2JWOA 2NUGA 2V87A 4F9AB 2UUAE 1OI8A 4Q28A 2JYAA 2BB8A 2HJJA 3ADGA 1YUIA 1XNRE 4V0XA 4FBQA 2YT4A 2V83A 2WZOA 2EPNA 3ZU0A 3FGAC 4DR2E 3P71C 4WSPA 5ADZA 4ORAA 2YU5A 4IYPC 2LBSB 2ODRD 1GZ6A 4H1YP 4HD0A 2DB2A 2JR1A 2RS7A 3T1YE 1FKAE 3QG5C 2V89A 2LUPB 1Z2XA 1SFEA 4ZX2A 2ENAA 3J80C 3UK3C 4DR7E 2H36X 3THNA 2EWLA 4B3RE 4DT2A 4FK5C 1S8EA 4DSYA 2WBSA 1PDAA 3KBPA 4GEQB 5BR8E 2YEQA 2J7JA 2UXCE 2WBUA 1X6HA 3D03A 2M9AA 3GVEA 4JI2E 2HGHA 2E5LE 2M4IA 2M7QA 5FLXC 4M2ZA 4DHLA 4IL1A 2DRPA 1T38A 1PKPA 2DSYA 4KWYA 1N36E 2EMWA 2LVHA 1IMUA 2BCDA 4F6MA 2G7HA 1DGCA 1N33E 4JYAE 1WXRA 3T1IA 2NABA 1PJTA 1QNTA 2FGGA 1A1GA 1FJMA 4DV2E 4ORBA 3K6QA 5KL6A 1YYWA 2GHFA 2A25A 4FBKA 2EOIA 4JI0E 1YPNA 3KZYA 1IT6A 3F6HA 5IXMB 2UXBE 4LF6E 4NZVA 2QJCA 4R2DA 4JV5E 4WPYA 2DIXA 3ZTVA 5DNYA 2EOJA 2EM3A 2MDRA 4V0VA 1SR9A 1J26A 3MSWA 1X6EA 1NEIA 4P7DA 5AASA 4DV0E 2JOGA 1AH5A 2N3HA 1STUA 5A6BD 4BCAA 4K0KE 1USHA 4M30A 5A69A 2EM9A 2EP3A 2E72A 2EN1A 2DLQA 1RMDA 3H69A 5IT9C 2DMYA 2EZ6A 2N8XA 1J5EE 4DV5E 4OR9A 2LJHA 2HHHE 1MF8A 2V88A 4LF7E 3C6KA 4ZVZA 2EM7A 1JK7A 1A1KA 3HPZA 4N4RB 4KZSA 1BBOA 2EM5A 3PSNA 2EOFA 1XNQE 2EMFA 1YSAC 2BDXA 4KHPE 1KJKA 2MC6A 3H60A 1KBPA 2UUBE 2EOSA 2L2NA 3BF2A 1S95A 2YTIA 2YTNA 2HYOA 2B3TB 2ZO9B 2YSOA 4XPNA 2LRSA 4LF9E 2YTEA 3MHSC 4KBPA 1MEYC 4DR3E 2EMAA 2KKNA 4R2CA 2IHR1 4B2OA 3EGGA 2LT7A 4YY3E 1QFCA 1M63A 5TSEA 4YKEA 4IJDA 3DW8C 4O24A 1HP1A 1T4NA 2I13A 1X3CA 2QFPA 2USHA 4Q7FA 3QFNA 4LTYA 1X5WA 4R8OA 4J8ZA 1G5BA 4F9BB 2I9IA 5CFFE 4MOVA 4F9CB 5JJTA 4WFTA 2V85A 3H63A 2VQFE 4H2IA 2EN7A 2EPUA 1S3MA 2FV4B 1TF3A 4JI4E 4UT2A 3V4YA 4BBYA 2PRTA 4BC7A 4R03A 4NXME 2O8GA 4B3SE 4DR5E 1T4OA 3C4BA 5LMUE 2EMIA 3KWRA 2NUEA 1HO5A 2ZBMA 3CK2A 4DUYE 4LF8E 3VYXA 2WDEA 1S70A 1X48A 3IWDA 2JOXA 4JI1E 2Z72A 2EQ1A 4JI6E 2YPNA 1ZBQA 1OIEA 3VK6A 1X49A 5AE3A 2O8AA 2EMYA 1FJGE 1XZWA 4H2GA 2YTPA 1G2FC 2EOXA 3H62B 4AQYE 4ZYDA 2Z06A 1O0WA 3MHHC 2CTDA 1ZAAC 2YTQA 4R2EA 2WDDA 2YTJA 2HY1A 2EN2A 1WJPA 2EPPA 4LU9A 2EMKA 1T4LB 3H61A 4NHRA 1Z1BA 2YTDA 2YVTA 4F6NA 4F54A 2EMCA 5A6AA 2VE7C 4RH8A 4DMIA 2EN8A 3BBGA 1EH8A 2D9HA 1JK2A 3ECRA 3H64A 4LACC 4R2QA 1YUJA 4O5GA 5JPFA 1PJSA 4BHBA 1UBDC 3EPLA 2EN3A 3HPSA 1XM7A 1GQEA 4DV6E 5GTUA 4Q35B 1IBKE 2EL4A 3K7WC 4WXCA 4LF5E 1IQSA 2K4VA 4O4KA 2RQLA 4LF4E 1UTEA 2WCC3 3T1HE 2EE8A 2EN6A 1WHNA 2GLIA 3IVEA 3C9FA 2V8QB 5LL6R 2NXFA 2LTSA 1HNZE 4WX9A 2EOYA 2L33A 4DV4E 4H2FA 2K7IA 1IBME 1BBGA 5INBA 2AHDA 3LL8A 3PSOA 2VQEE 2R17A 3QFMA 4JA9A 1YYKA 4LFBE 1DI2A 5HPEA 2EL5A 2EMGA 4R2SA 3HTXA 3J7AG 2YRHA 4RHBB 1MGTA 4IS1C 4X62E 4JI5E 2B7TA 1HNWE 2IE4C 5F3WA 4WYQB 3K7VC 1P47A 3JYFA 2BQ8X 2L3JA 4WXDA 1UF3A 2EM0A 2EJ4A 1YZ9A 3ADJA 1OIDA 2JVAA 2YZTA 4L5NC 4DR1E 4DR4E 1A1HA 3EPJA 3C6MA 5AE1A 1A1JA 4R2PA 2UXDE 2EMHA 1XMQE 3FIGA 2VF1A 4FCXA 3BIDA 4FBWA 2P6BA 2EPZA 1TCOA 4NXNE 1PJQA 1WRJA 1A1IA 1TN9A 2EM6A 4V0WA 1WHQA 1RQ0A 2EMXA 4H1SA 4ZYHA 2KHXA 4OX9E 3OTOE 4DV3E 3QFOA 4ORCA 5KL3A 3J7Yp 1HNXE 1IQOA 3AUZA 1UHZA 4KKZA 1LLMC 4I5LC 2EPXA 1Z2WA 2WBTA 2EN4A 4H2BA 3M99B 4ZYGA 4DV7E 4F2JC 3BGHA 2LV2A 3H68A 2F4VE 2L2KB 4UT3B 1QHWA 1NCSA 1EH6A 1YYOA 3OMLA 2LE2A 2RSIA 4O43A 3ZOQB 2VRDA 4R2AA 2ZM6E 2YTOA 4JI3E 1BB8A 1U32A 5KL2A 2EQ0A 4X65E 4JI7E 2CV9A 2EM8A 5AE2A 4OOGC 3QFKA 4P78A 1ZR9A 4DUZE 2DGCA 4G9JA 4J6OA 2MC5A 1XMOE 2A22A 1TF6A 2LTRA 1HPUA 5IV8B 1ZU1A 2NPPC 2UUCE 1N32E 1AAYA 4I8OA 5KL5A 2B7VA 4DR6E 4DKKA 1RC7A 2EOOA 4JA7A 1T70A 5LMNE 1QU6A 4MLVA 1ZBTA 3H09A 3DSCA 5JPEA 1HR0E 2EOQA 1AUIA 2EL6A 2EM4A 2YWQA 3JAMC 4B3TE 4WWLA 2GPIA 4X66E 4LFAE 2R1FA 1S3NA 3H66A 2ADRA 2NYMC 2KOUA 3ADIA 3F6GA 4M0VA 2EPKX 2EOMA 2YTFA 3FLOA 3IWCA 3EGHA 1N34E 2DXLA 2R76A 5EQVA 1YFHA 1N3GA 3HVQA 4HEIA 3AV0A 3VYYA 2WDCA 2CPNA 2F8BA 1G2DC 1KYQA 2YTGA 2MKDA 2L3CA 2YRMA 5KL4A 3HQ1A 2EQ3A 4R2RA 2LO3A 3TQMA 3IVDA 3JU0A 1L4SA 1II7A 4TUGA 3RQZA 3DF6A 2RPCA 1X47A 2NYLC 2CSHA 4X9JA 5T6JA 2XMOA 3KZZA 2V86A 5IWAE 2DMIA 2KONA 3LLHA 4YHHE 2B9DA 3EPKA 1F2IG 3RL5A 2LUQA 4MLQA 3C5WC 3RL3A 5A2QC 4I5NC 4BHCA 1WAO1 3TGHA 1JK1A 1DQ3A 4LFCE 2JXPA 3E0JA 3ADLA 4UT3A 2HYPA 5J28A 2L6MA 2EOHA 1UN6B 1SU1A 3LMLA 3VHTB 1IBLE 2UU9E 2IAEC 4GKKE 4ZYEA 2DLKA 3J81C 1NNWA 1V73A 1EH7A 2L2MA 2NA2A 2YRKA 3P1XA 2ZOAA 2EMBA 5A6BA 2QFRA 2WDFA 3H67A 3N5UA 3RMPA 3DJWA 3EPHA 5AC5A 2JPAA 4MP0A 4HTGA 3RL4A 3DSDA 2EPCA 2JOBA 3HXLA 2L8TA 4WSGA 2EORA 2HC5A 1I94E 3THOB 2ENCA 2Q8UA 4X64E 4GKJE 2EM2A 1T39A 5A6KA 1GTKA 2EPLX 5A6JA 1S3LA 2IE3C 2BBGA 2YU8A 2GJUA 2ELYA 3ICFA 1UILA 2ENHA 4UWQA 2YSPA 2MDGA 4B3ME 5C1VA 2EOEA 2EOZA 2M1SA 4MOYA 2EPMX 5LLQA 2EMLA 2N3GA 3E7BA 3EQ1A 2JY9A 3IWBA 4X8WA 2RS6A 4L8NA 4BMJA 4TUIA 3C4TA 4JI8E 2MKNA 2NUFA 2ELZA 2EPOA 2E1MA 2JP9A 5IOHA 1X6FA 3E7AA 5KL7A 2LMZA 5AC4A 2RSMA 4BC9A 2LCEA 2ODRC 4BS9A 1A1FA 2Z1AA 3IB7A 2FTXB 2CT1A 1T71A 3IB8A 2EPRA 1WARA 5B8IA 4F0ZA 1A1LA 3JTZA 1EKZA 2DFJA 2LJUA 4GZNC 3L00A 2DXNA 4M9VC 2EMZA 4DV1E 2L92A 2EPAA 2RTXA 1W24A 1B69A
chains in the Genus database with same CATH topology
2ZO9B 4XPNA 4KBPA 1OI8A 2KKNA 3IVDA 4V0XA 4B2OA 1II7A 2IE4C 3EGGA 4FBQA 3RQZA 4TUGA 5F3WA 3K7VC 2NYLC 1QFCA 3ZU0A 2XMOA 1M63A 3FGAC 3JYFA 3P71C 4YKEA 2BQ8X 4ORAA 3RL5A 1UF3A 3DW8C 4IYPC 4O24A 1HP1A 2USHA 3C5WC 2QFPA 4Q7FA 3RL3A 3QFNA 4HD0A 4H1YP 1OIDA 1WAO1 4I5NC 4LTYA 3TGHA 1G5BA 3E0JA 3QG5C 4MOVA 1Z2XA 4ZX2A 5JJTA 4UT3A 3H63A 3THNA 2HYPA 4FCXA 4H2IA 4DT2A 1S8EA 4DSYA 1S3MA 5J28A 4FBWA 2P6BA 4UT2A 1TCOA 3V4YA 3KBPA 1SU1A 4V0WA 2YEQA 4H1SA 2IAEC 2O8GA 3D03A 3GVEA 3QFOA 1HO5A 1NNWA 1V73A 2ZBMA 3CK2A 4ORCA 2WDEA 1S70A 2ZOAA 3AUZA 4KKZA 2Z72A 2QFRA 2WDFA 4DHLA 3H67A 4I5LC 1Z2WA 3N5UA 4IL1A 1OIEA 4H2BA 2O8AA 4MP0A 1XZWA 4H2GA 3RL4A 2BCDA 3H62B 3DSDA 3H68A 4UT3B 3T1IA 2Z06A 1QHWA 2WDDA 2HY1A 4O43A 1FJMA 3THOB 4ORBA 4LU9A 2Q8UA 3H61A 4FBKA 1U32A 1S3LA 2YVTA 2IE3C 2CV9A 2GJUA 3QFKA 3ICFA 1IT6A 4UWQA 5C1VA 4NZVA 2QJCA 4G9JA 4MOYA 4J6OA 2A22A 3ZTVA 1HPUA 2NPPC 5DNYA 4V0VA 3E7BA 3H64A 4LACC 2JOGA 4O5GA 5JPFA 4JA7A 1T70A 4TUIA 3DSCA 1USHA 1XM7A 5JPEA 5GTUA 1AUIA 3K7WC 3H69A 5IOHA 4WWLA 4O4KA 3E7AA 4OR9A 1UTEA 1MF8A 1S3NA 3H66A 2NYMC 2Z1AA 4ZVZA 3IB7A 3C9FA 1JK7A 3IVEA 1T71A 3IB8A 4M0VA 2NXFA 3PSNA 1WARA 3FLOA 5B8IA 5HPEA 4F0ZA 3EGHA 2DXLA 2BDXA 2DFJA 5EQVA 4H2FA 3H60A 1KBPA 3HVQA 5INBA 3AV0A 2AHDA 2DXNA 3LL8A 3PSOA 2WDCA 2R17A 3QFMA 4JA9A 1S95A 1W24A 2HYOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XPN A;  4KBP A;  1OI8 A;  2KKN A;  3IVD A;  4V0X A;  4B2O A;  1II7 A;  2IE4 C;  3EGG A;  4FBQ A;  3RQZ A;  4TUG A;  5F3W A;  3K7V C;  2NYL C;  1QFC A;  3ZU0 A;  2XMO A;  1M63 A;  3FGA C;  3JYF A;  3P71 C;  4YKE A;  2BQ8 X;  4ORA A;  3RL5 A;  1UF3 A;  3DW8 C;  4IYP C;  4O24 A;  1HP1 A;  2USH A;  3C5W C;  2QFP A;  4Q7F A;  3RL3 A;  3QFN A;  4H1Y P;  4HD0 A;  1OID A;  1WAO 1;  4I5N C;  4LTY A;  3TGH A;  1G5B A;  3QG5 C;  4MOV A;  1Z2X A;  4ZX2 A;  5JJT A;  4UT3 A;  3H63 A;  3THN A;  2HYP A;  4FCX A;  4H2I A;  4DT2 A;  1S8E A;  4DSY A;  1S3M A;  5J28 A;  4FBW A;  2P6B A;  4UT2 A;  1TCO A;  3V4Y A;  3KBP A;  1SU1 A;  4V0W A;  4H1S A;  2IAE C;  2O8G A;  3GVE A;  3QFO A;  1HO5 A;  1NNW A;  1V73 A;  2ZBM A;  3CK2 A;  4ORC A;  2WDE A;  1S70 A;  3AUZ A;  4KKZ A;  2Z72 A;  2QFR A;  2WDF A;  4DHL A;  3H67 A;  4I5L C;  1Z2W A;  3N5U A;  4IL1 A;  1OIE A;  4H2B A;  2O8A A;  4MP0 A;  1XZW A;  4H2G A;  3RL4 A;  2BCD A;  3H62 B;  3DSD A;  3H68 A;  4UT3 B;  3T1I A;  2Z06 A;  1QHW A;  2WDD A;  2HY1 A;  4O43 A;  1FJM A;  3THO B;  4ORB A;  4LU9 A;  2Q8U A;  3H61 A;  4FBK A;  1U32 A;  1S3L A;  2YVT A;  2IE3 C;  2CV9 A;  2GJU A;  3QFK A;  3ICF A;  1IT6 A;  4UWQ A;  5C1V A;  4NZV A;  2QJC A;  4G9J A;  4MOY A;  4J6O A;  2A22 A;  3ZTV A;  1HPU A;  2NPP C;  5DNY A;  4V0V A;  3E7B A;  3H64 A;  4LAC C;  2JOG A;  4O5G A;  5JPF A;  4JA7 A;  1T70 A;  4TUI A;  3DSC A;  1USH A;  1XM7 A;  5JPE A;  5GTU A;  1AUI A;  3K7W C;  3H69 A;  5IOH A;  4WWL A;  4O4K A;  3E7A A;  4OR9 A;  1UTE A;  1MF8 A;  1S3N A;  3H66 A;  2NYM C;  2Z1A A;  4ZVZ A;  3IB7 A;  3C9F A;  1JK7 A;  3IVE A;  1T71 A;  3IB8 A;  4M0V A;  2NXF A;  3PSN A;  1WAR A;  5B8I A;  5HPE A;  4F0Z A;  3EGH A;  2BDX A;  2DFJ A;  5EQV A;  4H2F A;  3H60 A;  1KBP A;  3HVQ A;  5INB A;  3AV0 A;  2AHD A;  3LL8 A;  3PSO A;  2WDC A;  2R17 A;  3QFM A;  4JA9 A;  1S95 A;  1W24 A;  2HYO A; 
#chains in the Genus database with same CATH topology
 2JWO A;  2NUG A;  2V87 A;  4F9A B;  2UUA E;  1OI8 A;  4Q28 A;  2JYA A;  2BB8 A;  2HJJ A;  3ADG A;  1YUI A;  1XNR E;  4V0X A;  4FBQ A;  2YT4 A;  2V83 A;  2WZO A;  2EPN A;  3ZU0 A;  3FGA C;  4DR2 E;  3P71 C;  4WSP A;  5ADZ A;  4ORA A;  2YU5 A;  4IYP C;  2LBS B;  2ODR D;  1GZ6 A;  4H1Y P;  4HD0 A;  2DB2 A;  2JR1 A;  2RS7 A;  3T1Y E;  1FKA E;  3QG5 C;  2V89 A;  2LUP B;  1Z2X A;  1SFE A;  4ZX2 A;  2ENA A;  3J80 C;  3UK3 C;  4DR7 E;  2H36 X;  3THN A;  2EWL A;  4B3R E;  4DT2 A;  4FK5 C;  1S8E A;  4DSY A;  2WBS A;  1PDA A;  3KBP A;  4GEQ B;  5BR8 E;  2YEQ A;  2J7J A;  2UXC E;  2WBU A;  1X6H A;  3D03 A;  2M9A A;  3GVE A;  4JI2 E;  2HGH A;  2E5L E;  2M4I A;  2M7Q A;  5FLX C;  4M2Z A;  4DHL A;  4IL1 A;  2DRP A;  1T38 A;  1PKP A;  2DSY A;  4KWY A;  1N36 E;  2EMW A;  2LVH A;  1IMU A;  2BCD A;  4F6M A;  2G7H A;  1DGC A;  1N33 E;  4JYA E;  1WXR A;  3T1I A;  2NAB A;  1PJT A;  1QNT A;  2FGG A;  1A1G A;  1FJM A;  4DV2 E;  4ORB A;  3K6Q A;  5KL6 A;  1YYW A;  2GHF A;  2A25 A;  4FBK A;  2EOI A;  4JI0 E;  1YPN A;  3KZY A;  1IT6 A;  3F6H A;  5IXM B;  2UXB E;  4LF6 E;  4NZV A;  2QJC A;  4R2D A;  4JV5 E;  4WPY A;  2DIX A;  3ZTV A;  5DNY A;  2EOJ A;  2EM3 A;  2MDR A;  4V0V A;  1SR9 A;  1J26 A;  3MSW A;  1X6E A;  1NEI A;  4P7D A;  5AAS A;  4DV0 E;  2JOG A;  1AH5 A;  2N3H A;  1STU A;  5A6B D;  4BCA A;  4K0K E;  1USH A;  4M30 A;  5A69 A;  2EM9 A;  2EP3 A;  2E72 A;  2EN1 A;  2DLQ A;  1RMD A;  3H69 A;  5IT9 C;  2DMY A;  2EZ6 A;  2N8X A;  1J5E E;  4DV5 E;  4OR9 A;  2LJH A;  2HHH E;  1MF8 A;  2V88 A;  4LF7 E;  3C6K A;  4ZVZ A;  2EM7 A;  1JK7 A;  1A1K A;  3HPZ A;  4N4R B;  4KZS A;  1BBO A;  2EM5 A;  3PSN A;  2EOF A;  1XNQ E;  2EMF A;  1YSA C;  2BDX A;  4KHP E;  1KJK A;  2MC6 A;  3H60 A;  1KBP A;  2UUB E;  2EOS A;  2L2N A;  3BF2 A;  1S95 A;  2YTI A;  2YTN A;  2HYO A;  2B3T B;  2ZO9 B;  2YSO A;  4XPN A;  2LRS A;  4LF9 E;  2YTE A;  3MHS C;  4KBP A;  1MEY C;  4DR3 E;  2EMA A;  2KKN A;  4R2C A;  2IHR 1;  4B2O A;  3EGG A;  2LT7 A;  4YY3 E;  1QFC A;  1M63 A;  5TSE A;  4YKE A;  4IJD A;  3DW8 C;  4O24 A;  1HP1 A;  1T4N A;  2I13 A;  1X3C A;  2QFP A;  2USH A;  4Q7F A;  3QFN A;  4LTY A;  1X5W A;  4R8O A;  4J8Z A;  1G5B A;  4F9B B;  2I9I A;  5CFF E;  4MOV A;  4F9C B;  5JJT A;  4WFT A;  2V85 A;  3H63 A;  2VQF E;  4H2I A;  2EN7 A;  2EPU A;  1S3M A;  2FV4 B;  1TF3 A;  4JI4 E;  4UT2 A;  3V4Y A;  4BBY A;  2PRT A;  4BC7 A;  4R03 A;  4NXM E;  2O8G A;  4B3S E;  4DR5 E;  1T4O A;  3C4B A;  5LMU E;  2EMI A;  3KWR A;  2NUE A;  1HO5 A;  2ZBM A;  3CK2 A;  4DUY E;  4LF8 E;  3VYX A;  2WDE A;  1S70 A;  1X48 A;  3IWD A;  2JOX A;  4JI1 E;  2Z72 A;  2EQ1 A;  4JI6 E;  2YPN A;  1ZBQ A;  1OIE A;  3VK6 A;  1X49 A;  5AE3 A;  2O8A A;  2EMY A;  1FJG E;  1XZW A;  4H2G A;  2YTP A;  1G2F C;  2EOX A;  3H62 B;  4AQY E;  4ZYD A;  2Z06 A;  1O0W A;  3MHH C;  2CTD A;  1ZAA C;  2YTQ A;  4R2E A;  2WDD A;  2YTJ A;  2HY1 A;  2EN2 A;  1WJP A;  2EPP A;  4LU9 A;  2EMK A;  1T4L B;  3H61 A;  4NHR A;  1Z1B A;  2YTD A;  2YVT A;  4F6N A;  4F54 A;  2EMC A;  5A6A A;  2VE7 C;  4RH8 A;  4DMI A;  2EN8 A;  3BBG A;  1EH8 A;  2D9H A;  1JK2 A;  3ECR A;  3H64 A;  4LAC C;  4R2Q A;  1YUJ A;  4O5G A;  5JPF A;  1PJS A;  4BHB A;  1UBD C;  3EPL A;  2EN3 A;  3HPS A;  1XM7 A;  1GQE A;  4DV6 E;  5GTU A;  4Q35 B;  1IBK E;  2EL4 A;  3K7W C;  4WXC A;  4LF5 E;  1IQS A;  2K4V A;  4O4K A;  2RQL A;  4LF4 E;  1UTE A;  2WCC 3;  3T1H E;  2EE8 A;  2EN6 A;  1WHN A;  2GLI A;  3IVE A;  3C9F A;  2V8Q B;  5LL6 R;  2NXF A;  2LTS A;  1HNZ E;  4WX9 A;  2EOY A;  2L33 A;  4DV4 E;  4H2F A;  2K7I A;  1IBM E;  1BBG A;  5INB A;  2AHD A;  3LL8 A;  3PSO A;  2VQE E;  2R17 A;  3QFM A;  4JA9 A;  1YYK A;  4LFB E;  1DI2 A;  5HPE A;  2EL5 A;  2EMG A;  4R2S A;  3HTX A;  3J7A G;  2YRH A;  4RHB B;  1MGT A;  4IS1 C;  4X62 E;  4JI5 E;  2B7T A;  1HNW E;  2IE4 C;  5F3W A;  4WYQ B;  3K7V C;  1P47 A;  3JYF A;  2BQ8 X;  2L3J A;  4WXD A;  1UF3 A;  2EM0 A;  2EJ4 A;  1YZ9 A;  3ADJ A;  1OID A;  2JVA A;  2YZT A;  4L5N C;  4DR1 E;  4DR4 E;  1A1H A;  3EPJ A;  3C6M A;  5AE1 A;  1A1J A;  4R2P A;  2UXD E;  2EMH A;  1XMQ E;  3FIG A;  2VF1 A;  4FCX A;  3BID A;  4FBW A;  2P6B A;  2EPZ A;  1TCO A;  4NXN E;  1PJQ A;  1WRJ A;  1A1I A;  1TN9 A;  2EM6 A;  4V0W A;  1WHQ A;  1RQ0 A;  2EMX A;  4H1S A;  4ZYH A;  2KHX A;  4OX9 E;  3OTO E;  4DV3 E;  3QFO A;  4ORC A;  5KL3 A;  3J7Y p;  1HNX E;  1IQO A;  3AUZ A;  1UHZ A;  4KKZ A;  1LLM C;  4I5L C;  2EPX A;  1Z2W A;  2WBT A;  2EN4 A;  4H2B A;  3M99 B;  4ZYG A;  4DV7 E;  4F2J C;  3BGH A;  2LV2 A;  3H68 A;  2F4V E;  2L2K B;  4UT3 B;  1QHW A;  1NCS A;  1EH6 A;  1YYO A;  3OML A;  2LE2 A;  2RSI A;  4O43 A;  3ZOQ B;  2VRD A;  4R2A A;  2ZM6 E;  2YTO A;  4JI3 E;  1BB8 A;  1U32 A;  5KL2 A;  2EQ0 A;  4X65 E;  4JI7 E;  2CV9 A;  2EM8 A;  5AE2 A;  4OOG C;  3QFK A;  4P78 A;  1ZR9 A;  4DUZ E;  2DGC A;  4G9J A;  4J6O A;  2MC5 A;  1XMO E;  2A22 A;  1TF6 A;  2LTR A;  1HPU A;  5IV8 B;  1ZU1 A;  2NPP C;  2UUC E;  1N32 E;  1AAY A;  4I8O A;  5KL5 A;  2B7V A;  4DR6 E;  4DKK A;  1RC7 A;  2EOO A;  4JA7 A;  1T70 A;  5LMN E;  1QU6 A;  4MLV A;  1ZBT A;  3H09 A;  3DSC A;  5JPE A;  1HR0 E;  2EOQ A;  1AUI A;  2EL6 A;  2EM4 A;  2YWQ A;  3JAM C;  4B3T E;  4WWL A;  2GPI A;  4X66 E;  4LFA E;  2R1F A;  1S3N A;  3H66 A;  2ADR A;  2NYM C;  2KOU A;  3ADI A;  3F6G A;  4M0V A;  2EPK X;  2EOM A;  2YTF A;  3FLO A;  3IWC A;  3EGH A;  1N34 E;  2DXL A;  2R76 A;  5EQV A;  1YFH A;  1N3G A;  3HVQ A;  4HEI A;  3AV0 A;  3VYY A;  2WDC A;  2CPN A;  2F8B A;  1G2D C;  1KYQ A;  2YTG A;  2MKD A;  2L3C A;  2YRM A;  5KL4 A;  3HQ1 A;  2EQ3 A;  4R2R A;  2LO3 A;  3TQM A;  3IVD A;  3JU0 A;  1L4S A;  1II7 A;  4TUG A;  3RQZ A;  3DF6 A;  2RPC A;  1X47 A;  2NYL C;  2CSH A;  4X9J A;  5T6J A;  2XMO A;  3KZZ A;  2V86 A;  5IWA E;  2DMI A;  2KON A;  3LLH A;  4YHH E;  2B9D A;  3EPK A;  1F2I G;  3RL5 A;  2LUQ A;  4MLQ A;  3C5W C;  3RL3 A;  5A2Q C;  4I5N C;  4BHC A;  1WAO 1;  3TGH A;  1JK1 A;  1DQ3 A;  4LFC E;  2JXP A;  3E0J A;  3ADL A;  4UT3 A;  2HYP A;  5J28 A;  2L6M A;  2EOH A;  1UN6 B;  1SU1 A;  3LML A;  3VHT B;  1IBL E;  2UU9 E;  2IAE C;  4GKK E;  4ZYE A;  2DLK A;  3J81 C;  1NNW A;  1V73 A;  1EH7 A;  2L2M A;  2NA2 A;  2YRK A;  3P1X A;  2ZOA A;  2EMB A;  5A6B A;  2QFR A;  2WDF A;  3H67 A;  3N5U A;  3RMP A;  3DJW A;  3EPH A;  5AC5 A;  2JPA A;  4MP0 A;  4HTG A;  3RL4 A;  3DSD A;  2EPC A;  2JOB A;  3HXL A;  2L8T A;  4WSG A;  2EOR A;  2HC5 A;  1I94 E;  3THO B;  2ENC A;  2Q8U A;  4X64 E;  4GKJ E;  2EM2 A;  1T39 A;  5A6K A;  1GTK A;  2EPL X;  5A6J A;  1S3L A;  2IE3 C;  2BBG A;  2YU8 A;  2GJU A;  2ELY A;  3ICF A;  1UIL A;  2ENH A;  4UWQ A;  2YSP A;  2MDG A;  4B3M E;  5C1V A;  2EOE A;  2EOZ A;  2M1S A;  4MOY A;  2EPM X;  5LLQ A;  2EML A;  2N3G A;  3E7B A;  3EQ1 A;  2JY9 A;  3IWB A;  4X8W A;  2RS6 A;  4L8N A;  4BMJ A;  4TUI A;  3C4T A;  4JI8 E;  2MKN A;  2NUF A;  2ELZ A;  2EPO A;  2E1M A;  2JP9 A;  5IOH A;  1X6F A;  3E7A A;  5KL7 A;  2LMZ A;  5AC4 A;  2RSM A;  4BC9 A;  2LCE A;  2ODR C;  4BS9 A;  1A1F A;  2Z1A A;  3IB7 A;  2FTX B;  2CT1 A;  1T71 A;  3IB8 A;  2EPR A;  1WAR A;  5B8I A;  4F0Z A;  1A1L A;  3JTZ A;  1EKZ A;  2DFJ A;  2LJU A;  4GZN C;  3L00 A;  2DXN A;  4M9V C;  2EMZ A;  4DV1 E;  2L92 A;  2EPA A;  2RTX A;  1W24 A;  1B69 A; 
#chains in the Genus database with same CATH homology
 2ZO9 B;  4XPN A;  4KBP A;  1OI8 A;  2KKN A;  3IVD A;  4V0X A;  4B2O A;  1II7 A;  2IE4 C;  3EGG A;  4FBQ A;  3RQZ A;  4TUG A;  5F3W A;  3K7V C;  2NYL C;  1QFC A;  3ZU0 A;  2XMO A;  1M63 A;  3FGA C;  3JYF A;  3P71 C;  4YKE A;  2BQ8 X;  4ORA A;  3RL5 A;  1UF3 A;  3DW8 C;  4IYP C;  4O24 A;  1HP1 A;  2USH A;  3C5W C;  2QFP A;  4Q7F A;  3RL3 A;  3QFN A;  4HD0 A;  4H1Y P;  1OID A;  1WAO 1;  4I5N C;  4LTY A;  3TGH A;  1G5B A;  3E0J A;  3QG5 C;  4MOV A;  1Z2X A;  4ZX2 A;  5JJT A;  4UT3 A;  3H63 A;  3THN A;  2HYP A;  4FCX A;  4H2I A;  4DT2 A;  1S8E A;  4DSY A;  1S3M A;  5J28 A;  4FBW A;  2P6B A;  4UT2 A;  1TCO A;  3V4Y A;  3KBP A;  1SU1 A;  4V0W A;  2YEQ A;  4H1S A;  2IAE C;  2O8G A;  3D03 A;  3GVE A;  3QFO A;  1HO5 A;  1NNW A;  1V73 A;  2ZBM A;  3CK2 A;  4ORC A;  2WDE A;  1S70 A;  2ZOA A;  3AUZ A;  4KKZ A;  2Z72 A;  2QFR A;  2WDF A;  4DHL A;  3H67 A;  4I5L C;  1Z2W A;  3N5U A;  4IL1 A;  1OIE A;  4H2B A;  2O8A A;  4MP0 A;  1XZW A;  4H2G A;  3RL4 A;  2BCD A;  3H62 B;  3DSD A;  3H68 A;  4UT3 B;  3T1I A;  2Z06 A;  1QHW A;  2WDD A;  2HY1 A;  4O43 A;  1FJM A;  3THO B;  4ORB A;  4LU9 A;  2Q8U A;  3H61 A;  4FBK A;  1U32 A;  1S3L A;  2YVT A;  2IE3 C;  2CV9 A;  2GJU A;  3QFK A;  3ICF A;  1IT6 A;  4UWQ A;  5C1V A;  4NZV A;  2QJC A;  4G9J A;  4MOY A;  4J6O A;  2A22 A;  3ZTV A;  1HPU A;  2NPP C;  5DNY A;  4V0V A;  3E7B A;  3H64 A;  4LAC C;  2JOG A;  4O5G A;  5JPF A;  4JA7 A;  1T70 A;  4TUI A;  3DSC A;  1USH A;  1XM7 A;  5JPE A;  5GTU A;  1AUI A;  3K7W C;  3H69 A;  5IOH A;  4WWL A;  4O4K A;  3E7A A;  4OR9 A;  1UTE A;  1MF8 A;  1S3N A;  3H66 A;  2NYM C;  2Z1A A;  4ZVZ A;  3IB7 A;  3C9F A;  1JK7 A;  3IVE A;  1T71 A;  3IB8 A;  4M0V A;  2NXF A;  3PSN A;  1WAR A;  3FLO A;  5B8I A;  5HPE A;  4F0Z A;  3EGH A;  2DXL A;  2BDX A;  2DFJ A;  5EQV A;  4H2F A;  3H60 A;  1KBP A;  3HVQ A;  5INB A;  3AV0 A;  2AHD A;  2DXN A;  3LL8 A;  3PSO A;  2WDC A;  2R17 A;  3QFM A;  4JA9 A;  1S95 A;  1W24 A;  2HYO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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