5BQHA

Discovery of a potent and selective mpges-1 inhibitor for the treatment of pain
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
148
structure length
148
Chain Sequence
SLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery and Characterization of 2-Acylaminoimidazole Microsomal Prostaglandin E Synthase-1 Inhibitors.
pubmed doi rcsb
molecule tags Isomerase/isomerase inhibitor
source organism Homo sapiens
molecule keywords Prostaglandin E synthase
total genus 64
structure length 148
sequence length 148
ec nomenclature ec 5.3.99.3: Prostaglandin-E synthase.
pdb deposition date 2015-05-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01124 MAPEG MAPEG family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.550 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Membrane associated eicosanoid/glutathione metabolism-like domain 5bqhA00
3LEOA 4JC7A 2UUHA 4NTFA 5BQGA 5BQIA 5K0IA 4J7YA 4JRZA 4YL1A 4JCZA 3PCVA 3B29A 4AL0A 5BQHA 4NTAA 4NTBA 4BPMA 4AL1A 2H8AA 4YK5A 2UUIA 4YL0A 4YL3A 2PNOA 4WABA 3DWWA 4J7TA 2Q7RA 5HV9A 3HKKA
chains in the Genus database with same CATH superfamily
4OIPF 4ZLDA 3AQBA 1NBBA 1C02A 4AE4A 256BA 3UGOA 2XL6A 3QW1A 3PMRA 2NUTB 1QVXA 1VB5A 4H4KC 4PACA 1OW8A 3US6A 5A6KA 2I8BA 1TR2A 3CSKA 3F46A 4EHPA 2LIGA 3DZAA 2YVKA 3L1MA 3AG4C 3NYJA 3ITFA 3RVZA 4CSAA 4W8KA 4MVMA 4OD5A 4DBQA 2XL8A 3EPVA 4NY3A 4JIOA 4U5CE 3RKOF 3OEOA 4RDAA 4CS9C 4Q5SF 4NTAA 3EFOB 4O6YA 4QI2A 2R7OA 4HFFB 1WWPA 4QDLA 3SNHA 5DS4A 1L7CA 1S7ZA 3KPHA 2AWCA 5JP7A 5FCLA 1E85A 4ER9A 1O5HA 1Z3IX 2W4MA 3ASNC 2GFHA 1ZHZA 2LD6A 3EGXB 1RXQA 1QLEC 3RF3A 3HNLA 5CI9A 3S0XA 2CNWA 3UMKA 2R7SA 3HJCA 1YAUO 1OKKD 3LEOA 3V5XA 4C3DA 2DI3A 3VM6A 5L0GA 2LQGA 1L3PA 4HEAJ 2L6HA 2F22A 3W8IA 1MMGA 2KNHA 2R7QA 2M64A 5GPGB 1LPEA 5L0CA 4J7YA 2L9JA 1TKNA 1TQGA 2JD3A 3PDMP 2HZ8A 1HW1A 2LCHA 3ZVRA 5A6BA 1KU2A 2P0NA 3GEIA 3CZ6A 4NTBA 4K0DA 1YARO 4UDVA 5DQTA 1A0BA 3F47A 1VK5A 3RIPA 5AC4A 1A7EA 5COGA 3TOLA 1Q0FA 4E7ZA 3B0UX 2R02A 3HNIA 2FGYA 4I44A 4E17A 1VLTA 3DWWA 2Q7RA 2VASA 4EBKA 2R7RA 1R5ID 4E0HA 4I1OB 3L8IA 2IXPA 3DAGA 2HFIA 2L7AA 3EHMA 3EQLF 4MNDA 2XXAA 3ABKC 2YWAA 3N2ZB 4MTFA 4CS9A 3EG9A 2Q3TA 2WL8A 4PJNA 5B3IA 3G50A 2ZXPA 3IQTA 4IB4A 4BJ6C 1Z23A 3BRJA 3C8GA 3JSEO 2QUPA 4XPWA 4G7HF 3T9OA 4DJ9A 1IZMA 1R4TA 3GM3A 4O6NA 2XS8A 4EIYA 1T01A 2J9VA 3ATPA 1OCZC 5T1DB 3ZQYA 4JURI 4YL3A 3JRMO 1ZZPA 1UG7A 2WZFA 3I4UA 3B9QA 2XLMA 1G4US 5A6AA 5B1BC 4BEMJ 2Y39A 3K1HA 4ONSA 1WASA 1V4AA 4JC7A 5D91A 1ORYA 5DQZA 2G62A 3MFNA 5E3AA 4EBBA 3JYHA 1MNDA 3WG7C 1VYKA 2EILC 1Z6AA 3NRHA 5JUAA 1M2VA 4O6MA 3FHDA 5E2QA 1D1AA 3U5SA 5JLIA 4HFKB 2P61A 1ORSC 2DB4A 1VMAA 1YVIA 2A6HF 3EHNA 3Q7GA 4XPXA 3UR3C 1AUEA 3L0IA 5T3WA 2IYLD 3L34A 1YDIA 1ZHYA 1QZXA 2EPMX 1NFOA 3B29A 4Q4ZF 3FOPA 1G5ZA 3H65A 5CIVA 2EPNA 2MHRA 4YK5A 2J8WA 1QQ3A 3JRTA 2J0XA 2IXOA 1CPRA 1J8MF 1OW6A 3TULA 4YWQA 3ZIBA 2OKUA 2CNWD 1G4WR 4XWJA 4U5FE 3KYJA 3FXHA 3TOMA 4G78A 5L0IA 1FFHA 1XZQA 1LS1A 2R03A 3AGTA 1H9GA 1WATA 3KL4A 3MBGA 3Q6NA 2Q9BA 1VLSA 2WVQA 4K1OA 4CS8C 1ST6A 4A4AA 3U0CA 1KTMA 4D4NA 3SXYA 1V55C 3K7DA 3U2MA 3FAJA 3M15A 4ANJA 5DS6A 5EK0A 3ZTZA 1VYIA 2OJED 2OQMA 2D5RB 1F1MA 3C18A 3ZC4A 4BJ6A 5A6BD 3S84A 2JX0A 1HE9A 2EIMC 1N1CA 3R2PA 4JJGA 4CJGA 1HY5A 4N6CA 2EINC 2QTVA 3U3BA 5L0FA 4IAQA 2J46A 4AL1A 3MYFA 2B0HA 3N0TA 3V7OA 2VCAA 3GORA 1Q0GA 3B71A 4KC9A 4YN0B 3WAQA 2HJMA 4XLPF 2H7VC 2HSBA 4O79A 1VTMP 2ZXOA 5KYUB 4NCQA 2PX3A 2PFDA 2Q4FA 3UMIA 4DRIB 2LK4A 2ZXWC 5EGYA 2XLDA 1V54C 2PX0A 2PBEA 2Y3BA 1BR1A 3FOOA 4JCHA 3DI5A 4LACB 4C3BA 3U3FA 1FTSA 3LESA 2NPUA 1EI7A 1BR4A 1NZEA 4MVZA 4AK9A 2Y69C 3I5PA 1LI5A 3QW0A 3C8GD 1O87A 4JRZA 1ZYRF 5AGFA 1BZ4A 4YT5A 4LDRA 2LFDA 3NKEA 1IW7F 3MLGA 1KNYA 4WJ0A 4DRJB 4O7GA 3RH3A 1G8XA 4E18A 2XM0A 1XZPA 2DYRC 2XM4A 1D0XA 4CSAC 3E9VA 2J45A 4DXWA 2R7XA 3FMSA 3DXJF 3NMIA 2BC5A 1WN0A 5COFA 1YZAA 2XLHA 4KBLA 1LM3B 2NUPB 2NUTA 1MNEA 1GGQA 3C62A 2EPLX 2R25A 1C03A 2H7BA 4JEAA 4IGGA 2LSEA 3OA1A 2YL1A 3HNKA 4XPYA 1OXKA 4JVSA 3KKBA 4JW1A 5KYWB 5AC5A 2E87A 4M63A 1YYXA 3G4ZA 2PF4E 2J9UA 3DE8A 3EFOA 3Q6MA 2YLIA 3U8PA 5KYNA 1H7IA 3O6XA 4BJ5A 4KNWA 4R32A 4ZLCA 4B6IA 5KYXB 1RJ9B 1SF8A 1UFBA 4OIRF 3EGXA 1ORJA 3C7JA 1JRAA 3QVYA 3TQOA 2FAPB 2YEVA 4HE8D 3M4BA 4LDKA 3RQFA 4J7TA 4JKVA 5TJ5E 2L6GA 3HKKA 4ULVA 3DJNB 2X0CA 3G4XA 3B0PA 1U6HA 1AVOB 1JPNA 1WOLA 3TD7A 1I5NA 1T5OA 1ZHWA 1LS4A 3ZTMA 5K0IA 3X1OA 4ULWA 5JT4A 4XEKA 1T9KA 4MVOA 3RFYA 2HV7A 2I15A 2WVOA 1MMNA 3SZRA 3VRCA 1E2XA 4JCZA 3LLKA 2V3CC 3VF0A 4C7OB 3ABMC 1SMYF 3GM2A 1FFTC 2J0WA 2OOCA 3K6BA 4RD9A 1TWAA 2H8AA 4A2NB 4EBJA 4KI2A 4G7OF 2UUIA 5F5FA 4LDQA 1FAPB 3KMIA 4MW3A 4FX5A 3ZG1A 4DBRA 4Z9HA 3NDBB 2C04A 3ASOC 2AWYA 2CCYA 1OR3A 4U9EA 3RQGA 5DLJA 2Q9AA 2CYDA 4E0IA 3C8ZA 4IWBA 5KYYA 4U5EE 1CPQA 4MVSA 1T6UA 2R7UA 1S05A 1LVKA 4CIHA 4Q7CA 3U9JA 3ZDLA 1NU7D 2NG1A 2Z15A 2KYHA 1VOMA 4CDAA 2MWQA 5A6JA 1NFNA 2KC3A 4PR9A 4LERA 2L6FA 4AX2A 1D0YA 4CS7A 2EPKX 2ZD9A 5FZTA 4G7ZF 4JJFA 4MW8A 1MMDA 3ZSUA 1RMVA 3K33A 2XLOA 1Z7Qc 1DOWA 2R05A 4EKWA 4XEVA 1D0ZA 4I3MA 3SYNA 5L0JA 3A11A 2PP4A 3TJ5A 2P6VA 1I4YA 1Y6DA 2CDQA 1RKEB 5L0HA 1APCA 1SR2A 2QY9A 4MS2A 4YJWA 4NTFA 3M1CB 5BQGA 4MTOA 1K04A 1J8YF 3VAYA 1Z63A 1RKCA 2A68F 4OD4A 2Y3GA 2QNLA 3J06A 3O39A 1M56C 2FFHA 2W45A 3GM1A 3R7CA 3LAYA 2VCBA 2A69F 4RBNA 5A69A 3U2LA 1FNTc 3E70C 3DD7A 4XQ1A 1ZW3A 2A1DD 4FESA 5CI8A 2KGOA 2GWWA 3MX3A 3LEVA 3W2VA 4AL0A 1PD1A 1ZVZA 2G3VA 1O3UA 2WZGA 2OJQA 3NMJA 2P1AA 2XL4A 2HS5A 3N24A 3EJNA 4N06A 3LNRA 3SEOA 4EUKB 2YL3A 2ETSA 3S27A 1HE1A 1PCXA 3K1IC 4P9TA 2W9YA 3EGDB 4JE9A 1ZHXA 3DAFA 3W8HA 4EWCA 2QE9A 2HMQA 2ASRA 4PJJA 3IQCA 1FMVA 3ABLC 2XS1A 4MVUA 4XEFA 5F5HA 4YT8A 3C63A 5HV9A 1CGME 3JZ0A 3M79A 1E84A 3LS1A 1QPUA 1D1BA 4PFOA 1ZU5A 3IPMO 3DMDA 3LUTB 4LLCA 3UGPA 1HMDA 4OIQF 4IARA 1LE4A 4N4WA 2VB6A 4AE4B 4IJJA 5L3VA 1PV3A 2JPUA 2YKZA 2M4EA 1LE2A 3GWNA 5COMA 5B3SC 3S90A 2ICWG 1LI7A 1K05A 5T3TA 3PHF2 3VYWA 4X0RA 3UNGC 3SXMA 2OG2A 1BBHA 4I1MA 3FVYA 3POVA 2EPOA 2W4BA 5JSLA 2WB7A 1FMWA 1SYQA 3V5ZA 4YT2A 5KYUA 1Q0KA 2BL2A 2MYSA 3NYLA 4PK4A 2KSFA 4CBEA 4CX9A 3CAXA 1NSGB 3AG3C 3O10A 2B0JA 4CS8A 4G0HA 1ZU4A 2LFFA 3ZWIA 1BR2A 1LKXA 2IOQA 2YLGA 3DM5A 2Y3DA 3RW0A 3T6BA 1EKYA 2YRFA 5DVWA 3ECSA 5L3QA 2RD9A 2OU6A 1T6IA 3HLZA 3EH1A 4C3EA 2IXNA 1C17M 1TWCA 2OEXA 3ZQVA 2GDCA 3A9CA 2HSQA 4N6HA 2DGJA 2XLVA 5L0DA 1PD0A 1DOVA 3AOUA 1AEPA 1NLXA 3K1IA 2YZSA 4U5DE 4IRUA 3T6JA 4WGZA 5HSWA 3U9MA 4U9DA 4P6IC 1YYJA 4BG0A 2Y3HA 4MVRA 4BJTA 4E7SA 1SZIA 2VH3A 3LJBA 3X2QC 1I4ZA 3AG2C 4F4BA 1M6TA 1WTYA 3EZIA 2H7OA 2NUPA 2YL7A 4WABA 4BPMA 3S9OA 2LP4A 1XWJA 3HNJA 4NC3A 1E86A 2AU5A 1OXBA 3DE9A 3EZHA 3IQ5A 4GQHA 3W4YA 3B0VC 2GA0A 2X51A 2BE5F 4LLEA 4J32B 5KYWA 3SP1A 2GAQA 1YA9A 4U5BE 5D92A 3CQZA 3TJ6A 3IHUA 4GEHA 2XXAB 5F28E 3JSZA 4JTCB 4CJOA 3JYYA 3EG9B 5KYXA 4MTGA 1HMOA 5JRAA 1RJ9A 2HJ3A 3C8GB 3WHNA 3AG1C 5E3CA 3L8JA 1YZCA 1Z5ZA 2WZLA 3JT1A 2R7VA 1JPJA 1JR8A 3RQEA 1YJGA 2ZPAA 2IXMA 3LLIA 1CGOA 1JMWA 3HTKC 2D4UA 1OQCA 3IEEA 1GQAA 3AJMA 3QMKA 5KYYB 4FAPB 3RYLA 1TFOB 4JTDB 2YLDA 1T6QA 3UMHA 3SXKA 1K40A 2J7PA 1EQ1A 1TFKB 2P7VA 3S29A 1RCPA 3AQCA 3OWTA 4JZAA 4DVYP 1A41A 3GWLA 3O55A 1M2VB 3BEHA 3T4RA 2R7TA 3H2VA 1JAFA 3QTHA 4C7OA 5E33A 4DOZA 4OINF 4DVZA 1JOGA 2Q00A 2AP3A 4JTAB 3K66A 1YA7O 2J9BA 3GEHA 3JTLO 4NQFA 4U5GA 4W8PA 4CIPA 1NG1A 2G3KA 2CGEA 3EH2A 4JEBA 1YLMA 5BUOA 2NSGA 3QVZA 2C03A 4J30B 4GYTA 3W2WA 3QZCA 3GODA 4CDVA 1OCOC 1QKRA 1OCRC 2IM8A 2TMVP 2RSEB 3FAPB 2Q9CA 1TWHA 2XLWA 3KH2A 3FDQA 2CW0F 4L6RA 1M57C 4BEJA 1ZHTA 2KQ9A 5EHHA 2A0BA 4P9FA 1OKKA 1OW7A 4YT4A 2J9WA 3NMKA 4KNVA 5DS5A 1U0BB 1MQVA 4K7BA 2KK1A 5IY5C 2OEVA 3RVYA 1BDJB 3Q7LA 2OCCC 3GEEA 3NKDA 1TWGA 4XLNF 1W2WA 2IBFA 3MYIA 3NYMA 2AVKA 4MQ9F 4FWVA 5JS5A 1B68A 3IQ6A 5BQHA 4XTKA 1M2OA 2XRHA 2YHSA 3CEXA 3M4CA 1H9TA 2WVNA 1U89A 4YL0A 2R9RB 4DRHB 3GANA 2KW3C 3LNMB 2EIJC 1MMAA 4PFPA 2YQYA 1RKEA 2VCCA 2VC9A 1ZW2A 1QSPA 2HMZA 3JCUQ 4Z9JA 2R7WA 2HUJA 2O9XA 3AGUA 2HKVA 4QI0A 1A7DA 4PJLA 2UUHA 1H6GA 3U8VA 3DJUB 4BJ1A 4OIOF 2NSFA 2HV6A 2KJGA 3I5QA 4H54A 2DYSC 1Y4CA 5BQIA 1WGWA 3KYIA 4IAOA 3DKAA 1Q0DA 3LS0A 3TK0A 1FR0A 2A6EF 2EIKC 3NG1A 3DM9B 4YL1A 1A7VA 2XLEA 1V74B 2A0UA 1Q0MA 1E83A 3PCVA 1D1CA 4U5HA 4CDYA 1NU9C 1LIHA 2V26A 3EGDA 1OCCC 4PJMA 4WGYA 5B1AC 3WODF 4BJ5C 1HW2A 4Z9IA 2XSEA 4MVQA 3SXZA 1GS9A 3V5YA 3H2UA 5JVEA 4D4XA 1CGNA 2ZXRA 2PNOA 2YL0A 1GM5A 1OR2A 2QLAA 3T6GB 1EA8A 3S28A 2J7PD 2L81A
chains in the Genus database with same CATH topology
3LEOA 4JC7A 2UUHA 4NTFA 5BQGA 5BQIA 5K0IA 4J7YA 4JRZA 4YL1A 4JCZA 3PCVA 3B29A 4AL0A 5BQHA 4NTAA 4NTBA 4BPMA 4AL1A 2H8AA 4YK5A 2UUIA 4YL0A 4YL3A 2PNOA 4WABA 3DWWA 4J7TA 2Q7RA 5HV9A 3HKKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LEO A;  4JC7 A;  2UUH A;  4NTF A;  5BQG A;  5BQI A;  5K0I A;  4J7Y A;  4JRZ A;  4YL1 A;  4JCZ A;  3PCV A;  3B29 A;  4AL0 A;  5BQH A;  4NTA A;  4NTB A;  4BPM A;  4AL1 A;  2H8A A;  4YK5 A;  2UUI A;  4YL0 A;  4YL3 A;  2PNO A;  4WAB A;  3DWW A;  4J7T A;  2Q7R A;  5HV9 A;  3HKK A; 
#chains in the Genus database with same CATH topology
 4OIP F;  4ZLD A;  3AQB A;  1NBB A;  1C02 A;  4AE4 A;  256B A;  3UGO A;  2XL6 A;  3QW1 A;  3PMR A;  2NUT B;  1QVX A;  1VB5 A;  4H4K C;  4PAC A;  1OW8 A;  3US6 A;  5A6K A;  2I8B A;  1TR2 A;  3CSK A;  3F46 A;  4EHP A;  2LIG A;  3DZA A;  2YVK A;  3L1M A;  3AG4 C;  3NYJ A;  3ITF A;  3RVZ A;  4CSA A;  4W8K A;  4MVM A;  4OD5 A;  4DBQ A;  2XL8 A;  3EPV A;  4NY3 A;  4JIO A;  4U5C E;  3RKO F;  3OEO A;  4RDA A;  4CS9 C;  4Q5S F;  4NTA A;  3EFO B;  4O6Y A;  4QI2 A;  2R7O A;  4HFF B;  1WWP A;  4QDL A;  3SNH A;  5DS4 A;  1L7C A;  1S7Z A;  3KPH A;  2AWC A;  5JP7 A;  5FCL A;  1E85 A;  4ER9 A;  1O5H A;  1Z3I X;  2W4M A;  3ASN C;  2GFH A;  1ZHZ A;  2LD6 A;  3EGX B;  1RXQ A;  1QLE C;  3RF3 A;  3HNL A;  5CI9 A;  3S0X A;  2CNW A;  3UMK A;  2R7S A;  3HJC A;  1YAU O;  1OKK D;  3LEO A;  3V5X A;  4C3D A;  2DI3 A;  3VM6 A;  5L0G A;  2LQG A;  1L3P A;  4HEA J;  2L6H A;  2F22 A;  3W8I A;  1MMG A;  2KNH A;  2R7Q A;  2M64 A;  5GPG B;  1LPE A;  5L0C A;  4J7Y A;  2L9J A;  1TKN A;  1TQG A;  2JD3 A;  3PDM P;  2HZ8 A;  1HW1 A;  2LCH A;  3ZVR A;  5A6B A;  1KU2 A;  2P0N A;  3GEI A;  3CZ6 A;  4NTB A;  4K0D A;  1YAR O;  4UDV A;  5DQT A;  1A0B A;  3F47 A;  1VK5 A;  3RIP A;  5AC4 A;  1A7E A;  5COG A;  3TOL A;  1Q0F A;  4E7Z A;  3B0U X;  2R02 A;  3HNI A;  2FGY A;  4I44 A;  4E17 A;  1VLT A;  3DWW A;  2Q7R A;  2VAS A;  4EBK A;  2R7R A;  1R5I D;  4E0H A;  4I1O B;  3L8I A;  2IXP A;  3DAG A;  2HFI A;  2L7A A;  3EHM A;  3EQL F;  4MND A;  2XXA A;  3ABK C;  2YWA A;  3N2Z B;  4MTF A;  4CS9 A;  3EG9 A;  2Q3T A;  2WL8 A;  4PJN A;  5B3I A;  3G50 A;  2ZXP A;  3IQT A;  4IB4 A;  4BJ6 C;  1Z23 A;  3BRJ A;  3C8G A;  3JSE O;  2QUP A;  4XPW A;  4G7H F;  3T9O A;  4DJ9 A;  1IZM A;  1R4T A;  3GM3 A;  4O6N A;  2XS8 A;  4EIY A;  1T01 A;  2J9V A;  3ATP A;  1OCZ C;  5T1D B;  3ZQY A;  4JUR I;  4YL3 A;  3JRM O;  1ZZP A;  1UG7 A;  2WZF A;  3I4U A;  3B9Q A;  2XLM A;  1G4U S;  5A6A A;  5B1B C;  4BEM J;  2Y39 A;  3K1H A;  4ONS A;  1WAS A;  1V4A A;  4JC7 A;  5D91 A;  1ORY A;  5DQZ A;  2G62 A;  3MFN A;  5E3A A;  4EBB A;  3JYH A;  1MND A;  3WG7 C;  1VYK A;  2EIL C;  1Z6A A;  3NRH A;  5JUA A;  1M2V A;  4O6M A;  3FHD A;  5E2Q A;  1D1A A;  3U5S A;  5JLI A;  4HFK B;  2P61 A;  1ORS C;  2DB4 A;  1VMA A;  1YVI A;  2A6H F;  3EHN A;  3Q7G A;  4XPX A;  3UR3 C;  1AUE A;  3L0I A;  5T3W A;  2IYL D;  3L34 A;  1YDI A;  1ZHY A;  1QZX A;  2EPM X;  1NFO A;  3B29 A;  4Q4Z F;  3FOP A;  1G5Z A;  3H65 A;  5CIV A;  2EPN A;  2MHR A;  4YK5 A;  2J8W A;  1QQ3 A;  3JRT A;  2J0X A;  2IXO A;  1CPR A;  1J8M F;  1OW6 A;  3TUL A;  4YWQ A;  3ZIB A;  2OKU A;  2CNW D;  1G4W R;  4XWJ A;  4U5F E;  3KYJ A;  3FXH A;  3TOM A;  4G78 A;  5L0I A;  1FFH A;  1XZQ A;  1LS1 A;  2R03 A;  3AGT A;  1H9G A;  1WAT A;  3KL4 A;  3MBG A;  3Q6N A;  2Q9B A;  1VLS A;  2WVQ A;  4K1O A;  4CS8 C;  1ST6 A;  4A4A A;  3U0C A;  1KTM A;  4D4N A;  3SXY A;  1V55 C;  3K7D A;  3U2M A;  3FAJ A;  3M15 A;  4ANJ A;  5DS6 A;  5EK0 A;  3ZTZ A;  1VYI A;  2OJE D;  2OQM A;  2D5R B;  1F1M A;  3C18 A;  3ZC4 A;  4BJ6 A;  5A6B D;  3S84 A;  2JX0 A;  1HE9 A;  2EIM C;  1N1C A;  3R2P A;  4JJG A;  4CJG A;  1HY5 A;  4N6C A;  2EIN C;  2QTV A;  3U3B A;  5L0F A;  4IAQ A;  2J46 A;  4AL1 A;  3MYF A;  2B0H A;  3N0T A;  3V7O A;  2VCA A;  3GOR A;  1Q0G A;  3B71 A;  4KC9 A;  4YN0 B;  3WAQ A;  2HJM A;  4XLP F;  2H7V C;  2HSB A;  4O79 A;  1VTM P;  2ZXO A;  5KYU B;  4NCQ A;  2PX3 A;  2PFD A;  2Q4F A;  3UMI A;  4DRI B;  2LK4 A;  2ZXW C;  5EGY A;  2XLD A;  1V54 C;  2PX0 A;  2PBE A;  2Y3B A;  1BR1 A;  3FOO A;  4JCH A;  3DI5 A;  4LAC B;  4C3B A;  3U3F A;  1FTS A;  3LES A;  2NPU A;  1EI7 A;  1BR4 A;  1NZE A;  4MVZ A;  4AK9 A;  2Y69 C;  3I5P A;  1LI5 A;  3QW0 A;  3C8G D;  1O87 A;  4JRZ A;  1ZYR F;  5AGF A;  1BZ4 A;  4YT5 A;  4LDR A;  2LFD A;  3NKE A;  1IW7 F;  3MLG A;  1KNY A;  4WJ0 A;  4DRJ B;  4O7G A;  3RH3 A;  1G8X A;  4E18 A;  2XM0 A;  1XZP A;  2DYR C;  2XM4 A;  1D0X A;  4CSA C;  3E9V A;  2J45 A;  4DXW A;  2R7X A;  3FMS A;  3DXJ F;  3NMI A;  2BC5 A;  1WN0 A;  5COF A;  1YZA A;  2XLH A;  4KBL A;  1LM3 B;  2NUP B;  2NUT A;  1MNE A;  1GGQ A;  3C62 A;  2EPL X;  2R25 A;  1C03 A;  2H7B A;  4JEA A;  4IGG A;  2LSE A;  3OA1 A;  2YL1 A;  3HNK A;  4XPY A;  1OXK A;  4JVS A;  3KKB A;  4JW1 A;  5KYW B;  5AC5 A;  2E87 A;  4M63 A;  1YYX A;  3G4Z A;  2PF4 E;  2J9U A;  3DE8 A;  3EFO A;  3Q6M A;  2YLI A;  3U8P A;  5KYN A;  1H7I A;  3O6X A;  4BJ5 A;  4KNW A;  4R32 A;  4ZLC A;  4B6I A;  5KYX B;  1RJ9 B;  1SF8 A;  1UFB A;  4OIR F;  3EGX A;  1ORJ A;  3C7J A;  1JRA A;  3QVY A;  3TQO A;  2FAP B;  2YEV A;  4HE8 D;  3M4B A;  4LDK A;  3RQF A;  4J7T A;  4JKV A;  5TJ5 E;  2L6G A;  3HKK A;  4ULV A;  3DJN B;  2X0C A;  3G4X A;  3B0P A;  1U6H A;  1AVO B;  1JPN A;  1WOL A;  3TD7 A;  1I5N A;  1T5O A;  1ZHW A;  1LS4 A;  3ZTM A;  5K0I A;  3X1O A;  4ULW A;  5JT4 A;  4XEK A;  1T9K A;  4MVO A;  3RFY A;  2HV7 A;  2I15 A;  2WVO A;  1MMN A;  3SZR A;  3VRC A;  1E2X A;  4JCZ A;  3LLK A;  2V3C C;  3VF0 A;  4C7O B;  3ABM C;  1SMY F;  3GM2 A;  1FFT C;  2J0W A;  2OOC A;  3K6B A;  4RD9 A;  1TWA A;  2H8A A;  4A2N B;  4EBJ A;  4KI2 A;  4G7O F;  2UUI A;  5F5F A;  4LDQ A;  1FAP B;  3KMI A;  4MW3 A;  4FX5 A;  3ZG1 A;  4DBR A;  4Z9H A;  3NDB B;  2C04 A;  3ASO C;  2AWY A;  2CCY A;  1OR3 A;  4U9E A;  3RQG A;  5DLJ A;  2Q9A A;  2CYD A;  4E0I A;  3C8Z A;  4IWB A;  5KYY A;  4U5E E;  1CPQ A;  4MVS A;  1T6U A;  2R7U A;  1S05 A;  1LVK A;  4CIH A;  4Q7C A;  3U9J A;  3ZDL A;  1NU7 D;  2NG1 A;  2Z15 A;  2KYH A;  1VOM A;  4CDA A;  2MWQ A;  5A6J A;  1NFN A;  2KC3 A;  4PR9 A;  4LER A;  2L6F A;  4AX2 A;  1D0Y A;  4CS7 A;  2EPK X;  2ZD9 A;  5FZT A;  4G7Z F;  4JJF A;  4MW8 A;  1MMD A;  3ZSU A;  1RMV A;  3K33 A;  2XLO A;  1Z7Q c;  1DOW A;  2R05 A;  4EKW A;  4XEV A;  1D0Z A;  4I3M A;  3SYN A;  5L0J A;  3A11 A;  2PP4 A;  3TJ5 A;  2P6V A;  1I4Y A;  1Y6D A;  2CDQ A;  1RKE B;  5L0H A;  1APC A;  1SR2 A;  2QY9 A;  4MS2 A;  4YJW A;  4NTF A;  3M1C B;  5BQG A;  4MTO A;  1K04 A;  1J8Y F;  3VAY A;  1Z63 A;  1RKC A;  2A68 F;  4OD4 A;  2Y3G A;  2QNL A;  3J06 A;  3O39 A;  1M56 C;  2FFH A;  2W45 A;  3GM1 A;  3R7C A;  3LAY A;  2VCB A;  2A69 F;  4RBN A;  5A69 A;  3U2L A;  1FNT c;  3E70 C;  3DD7 A;  4XQ1 A;  1ZW3 A;  2A1D D;  4FES A;  5CI8 A;  2KGO A;  2GWW A;  3MX3 A;  3LEV A;  3W2V A;  4AL0 A;  1PD1 A;  1ZVZ A;  2G3V A;  1O3U A;  2WZG A;  2OJQ A;  3NMJ A;  2P1A A;  2XL4 A;  2HS5 A;  3N24 A;  3EJN A;  4N06 A;  3LNR A;  3SEO A;  4EUK B;  2YL3 A;  2ETS A;  3S27 A;  1HE1 A;  1PCX A;  3K1I C;  4P9T A;  2W9Y A;  3EGD B;  4JE9 A;  1ZHX A;  3DAF A;  3W8H A;  4EWC A;  2QE9 A;  2HMQ A;  2ASR A;  4PJJ A;  3IQC A;  1FMV A;  3ABL C;  2XS1 A;  4MVU A;  4XEF A;  5F5H A;  4YT8 A;  3C63 A;  5HV9 A;  1CGM E;  3JZ0 A;  3M79 A;  1E84 A;  3LS1 A;  1QPU A;  1D1B A;  4PFO A;  1ZU5 A;  3IPM O;  3DMD A;  3LUT B;  4LLC A;  3UGP A;  1HMD A;  4OIQ F;  4IAR A;  1LE4 A;  4N4W A;  2VB6 A;  4AE4 B;  4IJJ A;  5L3V A;  1PV3 A;  2JPU A;  2YKZ A;  2M4E A;  1LE2 A;  3GWN A;  5COM A;  5B3S C;  3S90 A;  2ICW G;  1LI7 A;  1K05 A;  5T3T A;  3PHF 2;  3VYW A;  4X0R A;  3UNG C;  3SXM A;  2OG2 A;  1BBH A;  4I1M A;  3FVY A;  3POV A;  2EPO A;  2W4B A;  5JSL A;  2WB7 A;  1FMW A;  1SYQ A;  3V5Z A;  4YT2 A;  5KYU A;  1Q0K A;  2BL2 A;  2MYS A;  3NYL A;  4PK4 A;  2KSF A;  4CBE A;  4CX9 A;  3CAX A;  1NSG B;  3AG3 C;  3O10 A;  2B0J A;  4CS8 A;  4G0H A;  1ZU4 A;  2LFF A;  3ZWI A;  1BR2 A;  1LKX A;  2IOQ A;  2YLG A;  3DM5 A;  2Y3D A;  3RW0 A;  3T6B A;  1EKY A;  2YRF A;  5DVW A;  3ECS A;  5L3Q A;  2RD9 A;  2OU6 A;  1T6I A;  3HLZ A;  3EH1 A;  4C3E A;  2IXN A;  1C17 M;  1TWC A;  2OEX A;  3ZQV A;  2GDC A;  3A9C A;  2HSQ A;  4N6H A;  2DGJ A;  2XLV A;  5L0D A;  1PD0 A;  1DOV A;  3AOU A;  1AEP A;  1NLX A;  3K1I A;  2YZS A;  4U5D E;  4IRU A;  3T6J A;  4WGZ A;  5HSW A;  3U9M A;  4U9D A;  4P6I C;  1YYJ A;  4BG0 A;  2Y3H A;  4MVR A;  4BJT A;  4E7S A;  1SZI A;  2VH3 A;  3LJB A;  3X2Q C;  1I4Z A;  3AG2 C;  4F4B A;  1M6T A;  1WTY A;  3EZI A;  2H7O A;  2NUP A;  2YL7 A;  4WAB A;  4BPM A;  3S9O A;  2LP4 A;  1XWJ A;  3HNJ A;  4NC3 A;  1E86 A;  2AU5 A;  1OXB A;  3DE9 A;  3EZH A;  3IQ5 A;  4GQH A;  3W4Y A;  3B0V C;  2GA0 A;  2X51 A;  2BE5 F;  4LLE A;  4J32 B;  5KYW A;  3SP1 A;  2GAQ A;  1YA9 A;  4U5B E;  5D92 A;  3CQZ A;  3TJ6 A;  3IHU A;  4GEH A;  2XXA B;  5F28 E;  3JSZ A;  4JTC B;  4CJO A;  3JYY A;  3EG9 B;  5KYX A;  4MTG A;  1HMO A;  5JRA A;  1RJ9 A;  2HJ3 A;  3C8G B;  3WHN A;  3AG1 C;  5E3C A;  3L8J A;  1YZC A;  1Z5Z A;  2WZL A;  3JT1 A;  2R7V A;  1JPJ A;  1JR8 A;  3RQE A;  1YJG A;  2ZPA A;  2IXM A;  3LLI A;  1CGO A;  1JMW A;  3HTK C;  2D4U A;  1OQC A;  3IEE A;  1GQA A;  3AJM A;  3QMK A;  5KYY B;  4FAP B;  3RYL A;  1TFO B;  4JTD B;  2YLD A;  1T6Q A;  3UMH A;  3SXK A;  1K40 A;  2J7P A;  1EQ1 A;  1TFK B;  2P7V A;  3S29 A;  1RCP A;  3AQC A;  3OWT A;  4JZA A;  4DVY P;  1A41 A;  3GWL A;  3O55 A;  1M2V B;  3BEH A;  3T4R A;  2R7T A;  3H2V A;  1JAF A;  3QTH A;  4C7O A;  5E33 A;  4DOZ A;  4OIN F;  4DVZ A;  1JOG A;  2Q00 A;  2AP3 A;  4JTA B;  3K66 A;  1YA7 O;  2J9B A;  3GEH A;  3JTL O;  4NQF A;  4U5G A;  4W8P A;  4CIP A;  1NG1 A;  2G3K A;  2CGE A;  3EH2 A;  4JEB A;  1YLM A;  5BUO A;  2NSG A;  3QVZ A;  2C03 A;  4J30 B;  4GYT A;  3W2W A;  3QZC A;  3GOD A;  4CDV A;  1OCO C;  1QKR A;  1OCR C;  2IM8 A;  2TMV P;  2RSE B;  3FAP B;  2Q9C A;  1TWH A;  2XLW A;  3KH2 A;  3FDQ A;  2CW0 F;  4L6R A;  1M57 C;  4BEJ A;  1ZHT A;  2KQ9 A;  5EHH A;  2A0B A;  4P9F A;  1OKK A;  1OW7 A;  4YT4 A;  2J9W A;  3NMK A;  4KNV A;  5DS5 A;  1U0B B;  1MQV A;  4K7B A;  2KK1 A;  5IY5 C;  2OEV A;  3RVY A;  1BDJ B;  3Q7L A;  2OCC C;  3GEE A;  3NKD A;  1TWG A;  4XLN F;  1W2W A;  2IBF A;  3MYI A;  3NYM A;  2AVK A;  4MQ9 F;  4FWV A;  5JS5 A;  1B68 A;  3IQ6 A;  5BQH A;  4XTK A;  1M2O A;  2XRH A;  2YHS A;  3CEX A;  3M4C A;  1H9T A;  2WVN A;  1U89 A;  4YL0 A;  2R9R B;  4DRH B;  3GAN A;  2KW3 C;  3LNM B;  2EIJ C;  1MMA A;  4PFP A;  2YQY A;  1RKE A;  2VCC A;  2VC9 A;  1ZW2 A;  1QSP A;  2HMZ A;  3JCU Q;  4Z9J A;  2R7W A;  2HUJ A;  2O9X A;  3AGU A;  2HKV A;  4QI0 A;  1A7D A;  4PJL A;  2UUH A;  1H6G A;  3U8V A;  3DJU B;  4BJ1 A;  4OIO F;  2NSF A;  2HV6 A;  2KJG A;  3I5Q A;  4H54 A;  2DYS C;  1Y4C A;  5BQI A;  1WGW A;  3KYI A;  4IAO A;  3DKA A;  1Q0D A;  3LS0 A;  3TK0 A;  1FR0 A;  2A6E F;  2EIK C;  3NG1 A;  3DM9 B;  4YL1 A;  1A7V A;  2XLE A;  1V74 B;  2A0U A;  1Q0M A;  1E83 A;  3PCV A;  1D1C A;  4U5H A;  4CDY A;  1NU9 C;  1LIH A;  2V26 A;  3EGD A;  1OCC C;  4PJM A;  4WGY A;  5B1A C;  3WOD F;  4BJ5 C;  1HW2 A;  4Z9I A;  2XSE A;  4MVQ A;  3SXZ A;  1GS9 A;  3V5Y A;  3H2U A;  5JVE A;  4D4X A;  1CGN A;  2ZXR A;  2PNO A;  2YL0 A;  1GM5 A;  1OR2 A;  2QLA A;  3T6G B;  1EA8 A;  3S28 A;  2J7P D;  2L81 A; 
#chains in the Genus database with same CATH homology
 3LEO A;  4JC7 A;  2UUH A;  4NTF A;  5BQG A;  5BQI A;  5K0I A;  4J7Y A;  4JRZ A;  4YL1 A;  4JCZ A;  3PCV A;  3B29 A;  4AL0 A;  5BQH A;  4NTA A;  4NTB A;  4BPM A;  4AL1 A;  2H8A A;  4YK5 A;  2UUI A;  4YL0 A;  4YL3 A;  2PNO A;  4WAB A;  3DWW A;  4J7T A;  2Q7R A;  5HV9 A;  3HKK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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