5BQIA

Discovery of a potent and selective mpges-1 inhibitor for the treatment of pain
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
148
structure length
148
Chain Sequence
SLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery and Characterization of 2-Acylaminoimidazole Microsomal Prostaglandin E Synthase-1 Inhibitors.
pubmed doi rcsb
molecule tags Isomerase/isomerase inhibitor
source organism Homo sapiens
molecule keywords Prostaglandin E synthase
total genus 66
structure length 148
sequence length 148
ec nomenclature ec 5.3.99.3: Prostaglandin-E synthase.
pdb deposition date 2015-05-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01124 MAPEG MAPEG family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.550 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Membrane associated eicosanoid/glutathione metabolism-like domain 5bqiA00
2UUIA 2Q7RA 5BQGA 4BPMA 4JRZA 4J7YA 4AL1A 3HKKA 3B29A 4J7TA 4JC7A 5BQHA 4NTAA 4JCZA 2UUHA 4YK5A 5BQIA 5HV9A 3PCVA 2H8AA 4NTBA 4NTFA 4AL0A 4YL3A 4YL1A 4WABA 2PNOA 4YL0A 5K0IA 3DWWA 3LEOA
chains in the Genus database with same CATH superfamily
1WGWA 2NUPA 3NG1A 4OIPF 2G3KA 2YQYA 3L1MA 4RD9A 1VLTA 3BEHA 1YZAA 4O6YA 3W2VA 2AWYA 3AG2C 2Q4FA 1Q0FA 3GM2A 2Y3BA 3ECSA 4U5HA 3HNLA 2D5RB 2A0UA 3K1HA 2P1AA 3LNRA 4PFOA 5DS4A 1E86A 2QE9A 3NDBB 3S29A 3ZIBA 1OCZC 1WTYA 2C03A 2YLGA 4HFFB 1JMWA 4DOZA 2PP4A 3NYMA 1Q0GA 3CEXA 3EPVA 4K1OA 5A6AA 1PD1A 1EA8A 2RSEB 1E2XA 4XPXA 3EZIA 3US6A 3RW0A 2XLHA 2DYRC 5COFA 2FFHA 2R7SA 2ICWG 2IYLD 3DMDA 1YARO 2JX0A 2Y3HA 4O6NA 4BEJA 4EHPA 1TKNA 2JPUA 4JZAA 5A69A 1TFOB 4E7SA 4I3MA 4C7OB 1R4TA 1NG1A 4MW8A 4E0IA 2OU6A 3X1OA 1H7IA 2LFDA 2XL8A 4OD4A 2XLMA 3C18A 1A7VA 1BR2A 5JUAA 3TD7A 2L9JA 3B29A 3CQZA 3N24A 2Y69C 4JC7A 4XLNF 3AG4C 1U6HA 4F4BA 1FR0A 3U3BA 1Z3IX 2HFIA 3OEOA 3EQLF 4JCZA 2OQMA 1YLMA 2IXMA 1Z5ZA 2R9RB 4YK5A 3SXZA 3EG9A 3ZTMA 4CS9C 3DE8A 3UMHA 1MMNA 2AWCA 1OQCA 1A7DA 1NSGB 2MWQA 3EFOB 3W8HA 3VAYA 5B3IA 2TMVP 3TJ5A 1ZVZA 1SMYF 3MX3A 2LIGA 2M64A 2R25A 4MVSA 1ZHXA 2WVNA 5AC4A 4MNDA 3A9CA 2XRHA 2YL7A 4JTDB 1TWGA 3ZQVA 3GORA 3TK0A 2KYHA 4ULVA 1WOLA 2Q00A 3A11A 4JKVA 1V54C 1YJGA 1T6IA 3ASNC 3NKDA 1FMWA 3ABMC 3RFYA 1CPQA 1D0YA 3DJUB 2PX3A 4I1MA 3NKEA 4MVUA 4O6MA 1K05A 3JCUQ 4NC3A 4BJ5A 2ZXPA 3KH2A 1NFOA 4XEVA 3H2UA 4ONSA 1MMAA 4OD5A 4JTAB 2A1DD 3WG7C 4KBLA 1XZQA 2X0CA 2R7VA 3E9VA 3IEEA 2VCAA 4ER9A 3S90A 3ITFA 2GFHA 1C17M 1ST6A 1Y6DA 1JAFA 1Q0MA 1VYKA 3FAJA 2GDCA 4YL1A 4CJGA 5KYUA 4N06A 4B6IA 3SEOA 2IXPA 2DGJA 2KGOA 1S05A 3I5PA 5JP7A 1TFKB 1ORJA 4LERA 3SYNA 2EPLX 3EGDA 3GM3A 3JT1A 1NLXA 4GEHA 5FZTA 1FMVA 4RDAA 2A6HF 3U2MA 2XLWA 5B1AC 2R7WA 2VASA 2QTVA 3DAGA 5BQHA 1BBHA 1LM3B 2J9UA 3FAPB 1HMDA 3L8IA 5B3SC 1Q0KA 2R05A 4U5EE 4IGGA 2R7UA 1ZHZA 2NUPB 2VB6A 2YKZA 3HNKA 3JRTA 2CYDA 2Q9CA 1I5NA 5DQTA 1H9GA 4U9DA 2V26A 3GWLA 3H2VA 1C03A 3ABLC 4H54A 3HJCA 2BC5A 4O7GA 2XS8A 5D91A 2PNOA 3EZHA 1U0BB 4W8KA 1IZMA 2W45A 2O9XA 1RCPA 4MTFA 4FWVA 1ZHTA 2MHRA 2J7PD 1VLSA 4YT2A 2PX0A 2CGEA 4FX5A 3C62A 4Q7CA 4JURI 1O3UA 2Y3GA 3RVYA 3H65A 1G8XA 1YZCA 3G50A 3KL4A 2CNWD 3O39A 4PR9A 3RF3A 3RIPA 1RMVA 3IQTA 4J7TA 4G7ZF 2Y3DA 2NSFA 4JVSA 1R5ID 3AJMA 4P6IC 1G5ZA 3UMKA 3G4ZA 3C63A 2OKUA 1T6UA 4YT4A 1TR2A 4N6CA 2KJGA 3C8GA 3M79A 5CI8A 1MQVA 1QPUA 1MNDA 4K0DA 4JCHA 3O55A 2KQ9A 4JIOA 3K1IA 3EH1A 4MVZA 3J06A 2KSFA 1YDIA 1GGQA 2CDQA 4G7OF 4EUKB 2H7BA 3W8IA 2IBFA 3U5SA 2ZPAA 4MVRA 4EWCA 3LLKA 1FFHA 1RXQA 2AVKA 1HY5A 2HJ3A 2HSQA 3DXJF 2XM0A 5AC5A 1HW1A 2KK1A 2L7AA 2ZXWC 4NQFA 3NRHA 3EG9B 1Z7Qc 3S9OA 1D1AA 1FFTC 1SR2A 1UG7A 3FXHA 3JSEO 1RJ9A 4CJOA 3Q6MA 4XPYA 2XM4A 3ZQYA 2NG1A 1KNYA 3Q7LA 5A6BD 2HJMA 2XLEA 3MYIA 4Z9JA 2XLVA 4BJ6A 4EBJA 1M2VA 4M63A 3M4CA 3IPMO 2A0BA 4DVYP 2OJED 1OW8A 2OEXA 3GM1A 4PJMA 3KYJA 2X51A 5JS5A 2HUJA 3PDMP 1WATA 2EPMX 3DAFA 3GWNA 2IXOA 3S28A 1D0XA 2EIKC 4CX9A 1VTMP 1EI7A 1VOMA 1G4US 4G78A 5BUOA 1ZYRF 1Z63A 2XL4A 3ZG1A 2XXAA 2R7TA 5EK0A 3SXMA 3LUTB 1GM5A 3T6GB 1D0ZA 3U3FA 3G4XA 3MLGA 1OR3A 2RD9A 3KMIA 4LDRA 3FDQA 2QUPA 2R7QA 4JW1A 2P0NA 4O79A 3ZVRA 1OW7A 1K40A 3V5YA 2W9YA 5E3AA 1RKEB 2KNHA 3EHMA 4YT5A 4YN0B 4IJJA 2YEVA 2L81A 3HKKA 5TJ5E 2OEVA 4CDYA 1VB5A 2EINC 1UFBA 5KYUB 3QMKA 1RKCA 3AOUA 1QVXA 1OCOC 1O87A 5KYYA 2AU5A 5B1BC 2Q3TA 1FNTc 3QTHA 3UNGC 2LQGA 3V7OA 4AL0A 2HMZA 5KYXB 5KYNA 4HFKB 4MQ9F 1M56C 4EBBA 5F5HA 3DWWA 1SYQA 2I15A 1MMDA 2M4EA 3VF0A 5DS5A 3QW0A 1BDJB 1VYIA 2J46A 3K6BA 4P9TA 5L0FA 5GPGB 3Q7GA 2YZSA 4OIQF 1Y4CA 4L6RA 5JLIA 3CAXA 1E83A 1Z23A 2GWWA 2NUTB 1A0BA 1FAPB 4OIOF 2NSGA 4U5DE 4U9EA 3RH3A 5L0IA 5COMA 2J9VA 4MTGA 1TWCA 3UGOA 3ATPA 4XTKA 4G0HA 2ASRA 2UUHA 4KNVA 1QQ3A 3JRMO 1T6QA 4MVQA 2XSEA 3S0XA 4CIHA 5A6KA 5HSWA 4WGYA 2A68F 4XWJA 3FMSA 5JRAA 1PV3A 1TQGA 4XLPF 4CS8C 3LNMB 3RVZA 3HNIA 3ZWIA 2Y39A 3DM9B 4N6HA 3U8VA 1LE4A 2CCYA 4I1OB 3DM5A 3BRJA 3L34A 3W4YA 1JOGA 4IB4A 4BJ1A 1A7EA 3AG3C 4C3DA 3HLZA 4DVZA 2JD3A 1JPNA 2IOQA 1A41A 4W8PA 4GYTA 4JE9A 2Q7RA 1ZHWA 2OCCC 1JR8A 1NU7D 3C8GB 1AUEA 1DOVA 2YL1A 5DLJA 1LS1A 1MNEA 4JJFA 4ULWA 3U0CA 3EHNA 4ANJA 3GEEA 1U89A 2VCBA 3KKBA 3LESA 4U5FE 3TQOA 2J0WA 4D4XA 4JTCB 2A6EF 2HSBA 2B0HA 4Z9HA 3SXYA 1QKRA 2B0JA 4IWBA 3OA1A 4NTBA 1GS9A 4P9FA 4E18A 3IQ5A 4IARA 2W4MA 4JEAA 3R7CA 1ORSC 3DJNB 2J9WA 4BJ6C 2GAQA 1LKXA 4AE4A 3LEOA 3C8GD 4ZLDA 1SZIA 2VCCA 4J30B 5KYWA 1LE2A 2BL2A 1Z6AA 3RQFA 2YLIA 1LPEA 1JRAA 1M2VB 5F5FA 2GA0A 3LLIA 1L7CA 1F1MA 1NFNA 4I44A 1W2WA 1LI7A 4QI0A 3DZAA 3SP1A 1M6TA 1HE9A 1JPJA 2EIMC 2Q9BA 3ZTZA 4MVOA 1ZW2A 1M57C 2A69F 3DI5A 3RKOF 3C7JA 1HE1A 1CGME 3QVZA 3B71A 3X2QC 4A2NB 5L0HA 1DOWA 1LIHA 4YL3A 4FESA 4IAQA 1N1CA 4YWQA 4Q5SF 2J9BA 4CSAA 2DI3A 1SF8A 4CDAA 1H9TA 4BG0A 2YHSA 2ZXOA 5L0GA 3TJ6A 2QY9A 2YLDA 1PCXA 2FAPB 4DBRA 1V74B 1OW6A 2UUIA 2PFDA 2WZLA 3NYJA 5JSLA 4KI2A 4PACA 3KPHA 1YA9A 1AEPA 2I8BA 2R02A 3AQCA 4MW3A 1HW2A 1IW7F 1EKYA 3U9MA 2ZD9A 4EIYA 3C8ZA 3O10A 4FAPB 3EH2A 2J0XA 3HNJA 2XLOA 1LS4A 3ASOC 3B0UX 1ZHYA 2C04A 3TOMA 3S84A 2E87A 1MMGA 2J7PA 2WZFA 2H7VC 2P61A 4GQHA 4BJ5C 3I5QA 1KU2A 1QSPA 3LS1A 3QW1A 1LI5A 2LSEA 1BR4A 2LCHA 1E84A 1D1CA 2LK4A 3NYLA 5E33A 4XEFA 2V3CC 2W4BA 3IHUA 3U9JA 4JJGA 2PF4E 3B9QA 3T6BA 4CDVA 3PMRA 3CZ6A 4PJNA 3RQEA 4UDVA 2R03A 3L8JA 1APCA 1OKKA 2YWAA 5T3TA 2HMQA 1YA7O 2EPNA 3UMIA 2YL3A 3VM6A 3LEVA 2HZ8A 3V5XA 4NTAA 1AVOB 2OJQA 3SXKA 3AGUA 3EGXA 2YRFA 5L3VA 3R2PA 5HV9A 1TWAA 3K7DA 2EIJC 3FOPA 4Q4ZF 1T5OA 1GQAA 2P7VA 3JSZA 2XL6A 1FTSA 3EGDB 3T4RA 2LFFA 2P6VA 5JVEA 4HE8D 1EQ1A 3Q6NA 1XZPA 1ZU4A 2QLAA 4ZLCA 4WGZA 1PD0A 3JTLO 3T9OA 3LJBA 1J8MF 5A6BA 4BEMJ 4MS2A 1YYJA 2EPKX 4J7YA 1O5HA 4YJWA 4AL1A 3M1CB 4DRIB 4LDQA 1BZ4A 5DS6A 2R7RA 1KTMA 3N2ZB 3I4UA 2OOCA 3ZDLA 5A6JA 3UGPA 5F28E 1D1BA 2IXNA 4WJ0A 2QNLA 4U5GA 3U8PA 5DQZA 1J8YF 2G3VA 4AE4B 2H7OA 1I4ZA 3K66A 4Z9IA 5COGA 5KYWB 1LVKA 2H8AA 2J8WA 2L6HA 3FHDA 2HKVA 4CBEA 4E0HA 5T1DB 2WVOA 4A4AA 4YL0A 3M4BA 1CGOA 2G62A 5K0IA 3F47A 3GEHA 2LP4A 1VMAA 4XPWA 1E85A 3MBGA 1B68A 3NMIA 3N0TA 5E3CA 4C3BA 4EBKA 5AGFA 5DVWA 1YVIA 2EILC 3K1IC 3AGTA 3RYLA 5FCLA 4CSAC 2FGYA 4J32B 2YL0A 2XLDA 3PHF2 1OR2A 3GEIA 5L0CA 256BA 2ETSA 2YVKA 3V5ZA 2AP3A 2WZGA 2VC9A 4DBQA 2KC3A 4EKWA 1M2OA 4C7OA 1NZEA 1ZU5A 5L3QA 3OWTA 5IY5C 3DKAA 1RKEA 2EPOA 3TULA 3HTKC 3DD7A 4IAOA 2WB7A 4OINF 2DYSC 4H4KC 1H6GA 1OXBA 5JT4A 4XQ1A 3ZC4A 3FVYA 5E2QA 4G7HF 2KW3C 3O6XA 4LDKA 3GANA 1WASA 4KC9A 2J45A 4OIRF 4E7ZA 3QZCA 5L0DA 1RJ9B 1ZZPA 3LAYA 2MYSA 3TOLA 3W2WA 4D4NA 3WHNA 3L0IA 4PFPA 1V4AA 3LS0A 3U2LA 5L0JA 5KYXA 3EFOA 2PBEA 4PK4A 1C02A 1V55C 3JYHA 3B0PA 3T6JA 3WODF 1OXKA 4K7BA 4QDLA 2HV7A 4CS9A 4NCQA 2R7XA 1QZXA 1T01A 1Q0DA 3FOOA 4HEAJ 1OCRC 1TWHA 1I4YA 2DB4A 2XS1A 3ABKC 2HV6A 3NMJA 4IRUA 4LLCA 4U5BE 3CSKA 4MTOA 2F22A 3MYFA 2NUTA 1T9KA 2XXAB 4XEKA 5EHHA 3JZ0A 3NMKA 1OCCC 3UR3C 1NU9C 2WVQA 2ZXRA 3VRCA 2L6FA 3MFNA 1WN0A 1YAUO 3K33A 4DJ9A 1HMOA 5CIVA 3AQBA 4U5CE 3VYWA 4KNWA 4X0RA 5T3WA 4PJLA 4N4WA 4NY3A 3B0VC 3F46A 2L6GA 3GODA 3KYIA 1NBBA 3SZRA 4CIPA 4RBNA 3S27A 4AX2A 2R7OA 1QLEC 4LACB 3AG1C 3DE9A 3QVYA 5BQGA 3EGXB 5CI9A 4BPMA 1XWJA 1YYXA 4JRZA 4DRHB 5EGYA 2LD6A 3POVA 5KYYB 3JYYA 4PJJA 4DXWA 3M15A 4LLEA 4CS8A 2BE5F 2HS5A 3ZSUA 1WWPA 2OG2A 1L3PA 1S7ZA 5BQIA 3EJNA 1OKKD 5D92A 1K04A 4BJTA 1G4WR 2D4UA 1ZW3A 1CGNA 3PCVA 4AK9A 4R32A 4DRJB 4NTFA 3RQGA 2WL8A 2VH3A 4YT8A 4C3EA 4JEBA 4CS7A 2NPUA 2CW0F 4E17A 4WABA 2Q9AA 3E70C 1VK5A 2IM8A 3IQCA 1ORYA 1CPRA 4MVMA 2CNWA 3IQ6A 3SNHA 1BR1A 2Z15A 3WAQA 4QI2A
chains in the Genus database with same CATH topology
2UUIA 2Q7RA 5BQGA 4BPMA 4JRZA 4J7YA 4AL1A 3HKKA 3B29A 4J7TA 4JC7A 5BQHA 4NTAA 4JCZA 2UUHA 4YK5A 5BQIA 5HV9A 3PCVA 2H8AA 4NTBA 4NTFA 4AL0A 4YL3A 4YL1A 4WABA 2PNOA 4YL0A 5K0IA 3DWWA 3LEOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2UUI A;  2Q7R A;  5BQG A;  4BPM A;  4JRZ A;  4J7Y A;  4AL1 A;  3HKK A;  3B29 A;  4J7T A;  4JC7 A;  5BQH A;  4NTA A;  4JCZ A;  2UUH A;  4YK5 A;  5BQI A;  5HV9 A;  3PCV A;  2H8A A;  4NTB A;  4NTF A;  4AL0 A;  4YL3 A;  4YL1 A;  4WAB A;  2PNO A;  4YL0 A;  5K0I A;  3DWW A;  3LEO A; 
#chains in the Genus database with same CATH topology
 1WGW A;  2NUP A;  3NG1 A;  4OIP F;  2G3K A;  2YQY A;  3L1M A;  4RD9 A;  1VLT A;  3BEH A;  1YZA A;  4O6Y A;  3W2V A;  2AWY A;  3AG2 C;  2Q4F A;  1Q0F A;  3GM2 A;  2Y3B A;  3ECS A;  4U5H A;  3HNL A;  2D5R B;  2A0U A;  3K1H A;  2P1A A;  3LNR A;  4PFO A;  5DS4 A;  1E86 A;  2QE9 A;  3NDB B;  3S29 A;  3ZIB A;  1OCZ C;  1WTY A;  2C03 A;  2YLG A;  4HFF B;  1JMW A;  4DOZ A;  2PP4 A;  3NYM A;  1Q0G A;  3CEX A;  3EPV A;  4K1O A;  5A6A A;  1PD1 A;  1EA8 A;  2RSE B;  1E2X A;  4XPX A;  3EZI A;  3US6 A;  3RW0 A;  2XLH A;  2DYR C;  5COF A;  2FFH A;  2R7S A;  2ICW G;  2IYL D;  3DMD A;  1YAR O;  2JX0 A;  2Y3H A;  4O6N A;  4BEJ A;  4EHP A;  1TKN A;  2JPU A;  4JZA A;  5A69 A;  1TFO B;  4E7S A;  4I3M A;  4C7O B;  1R4T A;  1NG1 A;  4MW8 A;  4E0I A;  2OU6 A;  3X1O A;  1H7I A;  2LFD A;  2XL8 A;  4OD4 A;  2XLM A;  3C18 A;  1A7V A;  1BR2 A;  5JUA A;  3TD7 A;  2L9J A;  3B29 A;  3CQZ A;  3N24 A;  2Y69 C;  4JC7 A;  4XLN F;  3AG4 C;  1U6H A;  4F4B A;  1FR0 A;  3U3B A;  1Z3I X;  2HFI A;  3OEO A;  3EQL F;  4JCZ A;  2OQM A;  1YLM A;  2IXM A;  1Z5Z A;  2R9R B;  4YK5 A;  3SXZ A;  3EG9 A;  3ZTM A;  4CS9 C;  3DE8 A;  3UMH A;  1MMN A;  2AWC A;  1OQC A;  1A7D A;  1NSG B;  2MWQ A;  3EFO B;  3W8H A;  3VAY A;  5B3I A;  2TMV P;  3TJ5 A;  1ZVZ A;  1SMY F;  3MX3 A;  2LIG A;  2M64 A;  2R25 A;  4MVS A;  1ZHX A;  2WVN A;  5AC4 A;  4MND A;  3A9C A;  2XRH A;  2YL7 A;  4JTD B;  1TWG A;  3ZQV A;  3GOR A;  3TK0 A;  2KYH A;  4ULV A;  1WOL A;  2Q00 A;  3A11 A;  4JKV A;  1V54 C;  1YJG A;  1T6I A;  3ASN C;  3NKD A;  1FMW A;  3ABM C;  3RFY A;  1CPQ A;  1D0Y A;  3DJU B;  2PX3 A;  4I1M A;  3NKE A;  4MVU A;  4O6M A;  1K05 A;  3JCU Q;  4NC3 A;  4BJ5 A;  2ZXP A;  3KH2 A;  1NFO A;  4XEV A;  3H2U A;  4ONS A;  1MMA A;  4OD5 A;  4JTA B;  2A1D D;  3WG7 C;  4KBL A;  1XZQ A;  2X0C A;  2R7V A;  3E9V A;  3IEE A;  2VCA A;  4ER9 A;  3S90 A;  3ITF A;  2GFH A;  1C17 M;  1ST6 A;  1Y6D A;  1JAF A;  1Q0M A;  1VYK A;  3FAJ A;  2GDC A;  4YL1 A;  4CJG A;  5KYU A;  4N06 A;  4B6I A;  3SEO A;  2IXP A;  2DGJ A;  2KGO A;  1S05 A;  3I5P A;  5JP7 A;  1TFK B;  1ORJ A;  4LER A;  3SYN A;  2EPL X;  3EGD A;  3GM3 A;  3JT1 A;  1NLX A;  4GEH A;  5FZT A;  1FMV A;  4RDA A;  2A6H F;  3U2M A;  2XLW A;  5B1A C;  2R7W A;  2VAS A;  2QTV A;  3DAG A;  5BQH A;  1BBH A;  1LM3 B;  2J9U A;  3FAP B;  1HMD A;  3L8I A;  5B3S C;  1Q0K A;  2R05 A;  4U5E E;  4IGG A;  2R7U A;  1ZHZ A;  2NUP B;  2VB6 A;  2YKZ A;  3HNK A;  3JRT A;  2CYD A;  2Q9C A;  1I5N A;  5DQT A;  1H9G A;  4U9D A;  2V26 A;  3GWL A;  3H2V A;  1C03 A;  3ABL C;  4H54 A;  3HJC A;  2BC5 A;  4O7G A;  2XS8 A;  5D91 A;  2PNO A;  3EZH A;  1U0B B;  4W8K A;  1IZM A;  2W45 A;  2O9X A;  1RCP A;  4MTF A;  4FWV A;  1ZHT A;  2MHR A;  2J7P D;  1VLS A;  4YT2 A;  2PX0 A;  2CGE A;  4FX5 A;  3C62 A;  4Q7C A;  4JUR I;  1O3U A;  2Y3G A;  3RVY A;  3H65 A;  1G8X A;  1YZC A;  3G50 A;  3KL4 A;  2CNW D;  3O39 A;  4PR9 A;  3RF3 A;  3RIP A;  1RMV A;  3IQT A;  4J7T A;  4G7Z F;  2Y3D A;  2NSF A;  4JVS A;  1R5I D;  3AJM A;  4P6I C;  1G5Z A;  3UMK A;  3G4Z A;  3C63 A;  2OKU A;  1T6U A;  4YT4 A;  1TR2 A;  4N6C A;  2KJG A;  3C8G A;  3M79 A;  5CI8 A;  1MQV A;  1QPU A;  1MND A;  4K0D A;  4JCH A;  3O55 A;  2KQ9 A;  4JIO A;  3K1I A;  3EH1 A;  4MVZ A;  3J06 A;  2KSF A;  1YDI A;  1GGQ A;  2CDQ A;  4G7O F;  4EUK B;  2H7B A;  3W8I A;  2IBF A;  3U5S A;  2ZPA A;  4MVR A;  4EWC A;  3LLK A;  1FFH A;  1RXQ A;  2AVK A;  1HY5 A;  2HJ3 A;  2HSQ A;  3DXJ F;  2XM0 A;  5AC5 A;  1HW1 A;  2KK1 A;  2L7A A;  2ZXW C;  4NQF A;  3NRH A;  3EG9 B;  1Z7Q c;  3S9O A;  1D1A A;  1FFT C;  1SR2 A;  1UG7 A;  3FXH A;  3JSE O;  1RJ9 A;  4CJO A;  3Q6M A;  4XPY A;  2XM4 A;  3ZQY A;  2NG1 A;  1KNY A;  3Q7L A;  5A6B D;  2HJM A;  2XLE A;  3MYI A;  4Z9J A;  2XLV A;  4BJ6 A;  4EBJ A;  1M2V A;  4M63 A;  3M4C A;  3IPM O;  2A0B A;  4DVY P;  2OJE D;  1OW8 A;  2OEX A;  3GM1 A;  4PJM A;  3KYJ A;  2X51 A;  5JS5 A;  2HUJ A;  3PDM P;  1WAT A;  2EPM X;  3DAF A;  3GWN A;  2IXO A;  3S28 A;  1D0X A;  2EIK C;  4CX9 A;  1VTM P;  1EI7 A;  1VOM A;  1G4U S;  4G78 A;  5BUO A;  1ZYR F;  1Z63 A;  2XL4 A;  3ZG1 A;  2XXA A;  2R7T A;  5EK0 A;  3SXM A;  3LUT B;  1GM5 A;  3T6G B;  1D0Z A;  3U3F A;  3G4X A;  3MLG A;  1OR3 A;  2RD9 A;  3KMI A;  4LDR A;  3FDQ A;  2QUP A;  2R7Q A;  4JW1 A;  2P0N A;  4O79 A;  3ZVR A;  1OW7 A;  1K40 A;  3V5Y A;  2W9Y A;  5E3A A;  1RKE B;  2KNH A;  3EHM A;  4YT5 A;  4YN0 B;  4IJJ A;  2YEV A;  2L81 A;  3HKK A;  5TJ5 E;  2OEV A;  4CDY A;  1VB5 A;  2EIN C;  1UFB A;  5KYU B;  3QMK A;  1RKC A;  3AOU A;  1QVX A;  1OCO C;  1O87 A;  5KYY A;  2AU5 A;  5B1B C;  2Q3T A;  1FNT c;  3QTH A;  3UNG C;  2LQG A;  3V7O A;  4AL0 A;  2HMZ A;  5KYX B;  5KYN A;  4HFK B;  4MQ9 F;  1M56 C;  4EBB A;  5F5H A;  3DWW A;  1SYQ A;  2I15 A;  1MMD A;  2M4E A;  3VF0 A;  5DS5 A;  3QW0 A;  1BDJ B;  1VYI A;  2J46 A;  3K6B A;  4P9T A;  5L0F A;  5GPG B;  3Q7G A;  2YZS A;  4OIQ F;  1Y4C A;  4L6R A;  5JLI A;  3CAX A;  1E83 A;  1Z23 A;  2GWW A;  2NUT B;  1A0B A;  1FAP B;  4OIO F;  2NSG A;  4U5D E;  4U9E A;  3RH3 A;  5L0I A;  5COM A;  2J9V A;  4MTG A;  1TWC A;  3UGO A;  3ATP A;  4XTK A;  4G0H A;  2ASR A;  2UUH A;  4KNV A;  1QQ3 A;  3JRM O;  1T6Q A;  4MVQ A;  2XSE A;  3S0X A;  4CIH A;  5A6K A;  5HSW A;  4WGY A;  2A68 F;  4XWJ A;  3FMS A;  5JRA A;  1PV3 A;  1TQG A;  4XLP F;  4CS8 C;  3LNM B;  3RVZ A;  3HNI A;  3ZWI A;  2Y39 A;  3DM9 B;  4N6H A;  3U8V A;  1LE4 A;  2CCY A;  4I1O B;  3DM5 A;  3BRJ A;  3L34 A;  3W4Y A;  1JOG A;  4IB4 A;  4BJ1 A;  1A7E A;  3AG3 C;  4C3D A;  3HLZ A;  4DVZ A;  2JD3 A;  1JPN A;  2IOQ A;  1A41 A;  4W8P A;  4GYT A;  4JE9 A;  2Q7R A;  1ZHW A;  2OCC C;  1JR8 A;  1NU7 D;  3C8G B;  1AUE A;  1DOV A;  2YL1 A;  5DLJ A;  1LS1 A;  1MNE A;  4JJF A;  4ULW A;  3U0C A;  3EHN A;  4ANJ A;  3GEE A;  1U89 A;  2VCB A;  3KKB A;  3LES A;  4U5F E;  3TQO A;  2J0W A;  4D4X A;  4JTC B;  2A6E F;  2HSB A;  2B0H A;  4Z9H A;  3SXY A;  1QKR A;  2B0J A;  4IWB A;  3OA1 A;  4NTB A;  1GS9 A;  4P9F A;  4E18 A;  3IQ5 A;  4IAR A;  2W4M A;  4JEA A;  3R7C A;  1ORS C;  3DJN B;  2J9W A;  4BJ6 C;  2GAQ A;  1LKX A;  4AE4 A;  3LEO A;  3C8G D;  4ZLD A;  1SZI A;  2VCC A;  4J30 B;  5KYW A;  1LE2 A;  2BL2 A;  1Z6A A;  3RQF A;  2YLI A;  1LPE A;  1JRA A;  1M2V B;  5F5F A;  2GA0 A;  3LLI A;  1L7C A;  1F1M A;  1NFN A;  4I44 A;  1W2W A;  1LI7 A;  4QI0 A;  3DZA A;  3SP1 A;  1M6T A;  1HE9 A;  1JPJ A;  2EIM C;  2Q9B A;  3ZTZ A;  4MVO A;  1ZW2 A;  1M57 C;  2A69 F;  3DI5 A;  3RKO F;  3C7J A;  1HE1 A;  1CGM E;  3QVZ A;  3B71 A;  3X2Q C;  4A2N B;  5L0H A;  1DOW A;  1LIH A;  4YL3 A;  4FES A;  4IAQ A;  1N1C A;  4YWQ A;  4Q5S F;  2J9B A;  4CSA A;  2DI3 A;  1SF8 A;  4CDA A;  1H9T A;  4BG0 A;  2YHS A;  2ZXO A;  5L0G A;  3TJ6 A;  2QY9 A;  2YLD A;  1PCX A;  2FAP B;  4DBR A;  1V74 B;  1OW6 A;  2UUI A;  2PFD A;  2WZL A;  3NYJ A;  5JSL A;  4KI2 A;  4PAC A;  3KPH A;  1YA9 A;  1AEP A;  2I8B A;  2R02 A;  3AQC A;  4MW3 A;  1HW2 A;  1IW7 F;  1EKY A;  3U9M A;  2ZD9 A;  4EIY A;  3C8Z A;  3O10 A;  4FAP B;  3EH2 A;  2J0X A;  3HNJ A;  2XLO A;  1LS4 A;  3ASO C;  3B0U X;  1ZHY A;  2C04 A;  3TOM A;  3S84 A;  2E87 A;  1MMG A;  2J7P A;  2WZF A;  2H7V C;  2P61 A;  4GQH A;  4BJ5 C;  3I5Q A;  1KU2 A;  1QSP A;  3LS1 A;  3QW1 A;  1LI5 A;  2LSE A;  1BR4 A;  2LCH A;  1E84 A;  1D1C A;  2LK4 A;  3NYL A;  5E33 A;  4XEF A;  2V3C C;  2W4B A;  3IHU A;  3U9J A;  4JJG A;  2PF4 E;  3B9Q A;  3T6B A;  4CDV A;  3PMR A;  3CZ6 A;  4PJN A;  3RQE A;  4UDV A;  2R03 A;  3L8J A;  1APC A;  1OKK A;  2YWA A;  5T3T A;  2HMQ A;  1YA7 O;  2EPN A;  3UMI A;  2YL3 A;  3VM6 A;  3LEV A;  2HZ8 A;  3V5X A;  4NTA A;  1AVO B;  2OJQ A;  3SXK A;  3AGU A;  3EGX A;  2YRF A;  5L3V A;  3R2P A;  5HV9 A;  1TWA A;  3K7D A;  2EIJ C;  3FOP A;  4Q4Z F;  1T5O A;  1GQA A;  2P7V A;  3JSZ A;  2XL6 A;  1FTS A;  3EGD B;  3T4R A;  2LFF A;  2P6V A;  5JVE A;  4HE8 D;  1EQ1 A;  3Q6N A;  1XZP A;  1ZU4 A;  2QLA A;  4ZLC A;  4WGZ A;  1PD0 A;  3JTL O;  3T9O A;  3LJB A;  1J8M F;  5A6B A;  4BEM J;  4MS2 A;  1YYJ A;  2EPK X;  4J7Y A;  1O5H A;  4YJW A;  4AL1 A;  3M1C B;  4DRI B;  4LDQ A;  1BZ4 A;  5DS6 A;  2R7R A;  1KTM A;  3N2Z B;  3I4U A;  2OOC A;  3ZDL A;  5A6J A;  3UGP A;  5F28 E;  1D1B A;  2IXN A;  4WJ0 A;  2QNL A;  4U5G A;  3U8P A;  5DQZ A;  1J8Y F;  2G3V A;  4AE4 B;  2H7O A;  1I4Z A;  3K66 A;  4Z9I A;  5COG A;  5KYW B;  1LVK A;  2H8A A;  2J8W A;  2L6H A;  3FHD A;  2HKV A;  4CBE A;  4E0H A;  5T1D B;  2WVO A;  4A4A A;  4YL0 A;  3M4B A;  1CGO A;  2G62 A;  5K0I A;  3F47 A;  3GEH A;  2LP4 A;  1VMA A;  4XPW A;  1E85 A;  3MBG A;  1B68 A;  3NMI A;  3N0T A;  5E3C A;  4C3B A;  4EBK A;  5AGF A;  5DVW A;  1YVI A;  2EIL C;  3K1I C;  3AGT A;  3RYL A;  5FCL A;  4CSA C;  2FGY A;  4J32 B;  2YL0 A;  2XLD A;  3PHF 2;  1OR2 A;  3GEI A;  5L0C A;  256B A;  2ETS A;  2YVK A;  3V5Z A;  2AP3 A;  2WZG A;  2VC9 A;  4DBQ A;  2KC3 A;  4EKW A;  1M2O A;  4C7O A;  1NZE A;  1ZU5 A;  5L3Q A;  3OWT A;  5IY5 C;  3DKA A;  1RKE A;  2EPO A;  3TUL A;  3HTK C;  3DD7 A;  4IAO A;  2WB7 A;  4OIN F;  2DYS C;  4H4K C;  1H6G A;  1OXB A;  5JT4 A;  4XQ1 A;  3ZC4 A;  3FVY A;  5E2Q A;  4G7H F;  2KW3 C;  3O6X A;  4LDK A;  3GAN A;  1WAS A;  4KC9 A;  2J45 A;  4OIR F;  4E7Z A;  3QZC A;  5L0D A;  1RJ9 B;  1ZZP A;  3LAY A;  2MYS A;  3TOL A;  3W2W A;  4D4N A;  3WHN A;  3L0I A;  4PFP A;  1V4A A;  3LS0 A;  3U2L A;  5L0J A;  5KYX A;  3EFO A;  2PBE A;  4PK4 A;  1C02 A;  1V55 C;  3JYH A;  3B0P A;  3T6J A;  3WOD F;  1OXK A;  4K7B A;  4QDL A;  2HV7 A;  4CS9 A;  4NCQ A;  2R7X A;  1QZX A;  1T01 A;  1Q0D A;  3FOO A;  4HEA J;  1OCR C;  1TWH A;  1I4Y A;  2DB4 A;  2XS1 A;  3ABK C;  2HV6 A;  3NMJ A;  4IRU A;  4LLC A;  4U5B E;  3CSK A;  4MTO A;  2F22 A;  3MYF A;  2NUT A;  1T9K A;  2XXA B;  4XEK A;  5EHH A;  3JZ0 A;  3NMK A;  1OCC C;  3UR3 C;  1NU9 C;  2WVQ A;  2ZXR A;  3VRC A;  2L6F A;  3MFN A;  1WN0 A;  1YAU O;  3K33 A;  4DJ9 A;  1HMO A;  5CIV A;  3AQB A;  4U5C E;  3VYW A;  4KNW A;  4X0R A;  5T3W A;  4PJL A;  4N4W A;  4NY3 A;  3B0V C;  3F46 A;  2L6G A;  3GOD A;  3KYI A;  1NBB A;  3SZR A;  4CIP A;  4RBN A;  3S27 A;  4AX2 A;  2R7O A;  1QLE C;  4LAC B;  3AG1 C;  3DE9 A;  3QVY A;  5BQG A;  3EGX B;  5CI9 A;  4BPM A;  1XWJ A;  1YYX A;  4JRZ A;  4DRH B;  5EGY A;  2LD6 A;  3POV A;  5KYY B;  3JYY A;  4PJJ A;  4DXW A;  3M15 A;  4LLE A;  4CS8 A;  2BE5 F;  2HS5 A;  3ZSU A;  1WWP A;  2OG2 A;  1L3P A;  1S7Z A;  5BQI A;  3EJN A;  1OKK D;  5D92 A;  1K04 A;  4BJT A;  1G4W R;  2D4U A;  1ZW3 A;  1CGN A;  3PCV A;  4AK9 A;  4R32 A;  4DRJ B;  4NTF A;  3RQG A;  2WL8 A;  2VH3 A;  4YT8 A;  4C3E A;  4JEB A;  4CS7 A;  2NPU A;  2CW0 F;  4E17 A;  4WAB A;  2Q9A A;  3E70 C;  1VK5 A;  2IM8 A;  3IQC A;  1ORY A;  1CPR A;  4MVM A;  2CNW A;  3IQ6 A;  3SNH A;  1BR1 A;  2Z15 A;  3WAQ A;  4QI2 A; 
#chains in the Genus database with same CATH homology
 2UUI A;  2Q7R A;  5BQG A;  4BPM A;  4JRZ A;  4J7Y A;  4AL1 A;  3HKK A;  3B29 A;  4J7T A;  4JC7 A;  5BQH A;  4NTA A;  4JCZ A;  2UUH A;  4YK5 A;  5BQI A;  5HV9 A;  3PCV A;  2H8A A;  4NTB A;  4NTF A;  4AL0 A;  4YL3 A;  4YL1 A;  4WAB A;  2PNO A;  4YL0 A;  5K0I A;  3DWW A;  3LEO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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