2AAEA

The role of histidine-40 in ribonuclease t1 catalysis: three-dimensional structures of the partially active his40lys mutant
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
104
structure length
104
Chain Sequence
ACDYTCGSNCYSSSDVSTAQAAGYKLHEDGETVGSNSYPKKYNNYEGFDFSVSSPYYEWPILSSGDVYSGGSPGADRVVFNENNQLAGVITHTGASGNNFVECT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Role of histidine-40 in ribonuclease T1 catalysis: three-dimensionalstructures of the partially active His40Lys mutant.
pubmed doi rcsb
molecule tags Hydrolase(endoribonuclease)
source organism Aspergillus oryzae
molecule keywords RIBONUCLEASE T1
total genus 25
structure length 104
sequence length 104
ec nomenclature ec 3.1.27.3: Ribonuclease T(1).
pdb deposition date 1992-09-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00545 Ribonuclease ribonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.450.30 Alpha Beta Roll Nuclear Transport Factor 2; Chain: A, Microbial ribonucleases 2aaeA00
1RSNA 1I0VA 5HOHA 1I70A 1Q9EA 3D4AA 1I0XA 1BNSA 7GSPA 4GHOA 1RNBA 1RLSA 1B2MA 3SYUA 4J5GA 1C54A 1BRIA 1B2ZA 1RGFA 2KAAA 1BNIA 1BRKA 7RNTA 1BAOA 1GMRA 1TTOA 1X1UA 1I2EA 1BIRA 1MGRA 1RN4A 2KF5A 4HAAA 1GSPA 2BIRA 1RHLA 3A5EA 1B27A 1ZGXA 1BNJA 1G02A 1BU4A 5RNTA 1FZUA 1RGEA 1FYSA 2GSPA 1A2PA 1T2HA 1T2IA 1YVSA 1TRPA 3DGYA 2F5MA 6RNTA 9RNTA 1B2SA 3AHWA 3AHSA 1FUTA 1LOWA 1X1XA 1RTUA 4RNTA 8RNTA 5BU4A 1BUJA 1UCJA 1GMQA 1I8VA 3HOHA 1RCLA 1B20A 1I2FA 3GSPA 1MGWA 1JBRA 1BRHA 4J5KA 1BRGA 3KCHA 4GSPA 1BSEA 2F5WA 1RGGA 1B3SA 3RNTA 1RGKA 1HYFA 1I3FA 1HZ1A 1PYLA 2BU4A 2AADA 1BANA 1I3IA 4HOHA 1FUSA 1GMPA 2KF4A 1BNGA 1BNFA 1LNIA 1X1YA 2AAEA 2KF3A 1JBTA 5BIRA 1BSCA 2F4YA 1LOYA 3Q3FA 1GOVA 3BIRA 3URPA 1FW7A 3D5GA 1SARA 3WR2A 1DE3A 2SARA 1YGWA 1GOUA 1R4YA 1RMSA 2C4BA 1BGSA 1UCKA 1B2UA 1IYYA 4BIRA 1UCIA 1BOXA 1GOYA 1AY7A 2HOHA 1JBSA 1LOVA 2RNTA 1RGAA 2KF6A 1PY3A 5GSPA 4BU4A 1RNTA 1BSDA 1YNVX 3AGNA 2ZA4A 3BU4A 1BVIA 1BRJA 3WHOA 1RCKA 1RGHA 3AGOA 6GSPA 1BNRA 1BSBA 1BSAA 1I2GA 1TRQA 1B2XA 1RN1A 1UCLA 1X1WA 1B21A 1BRNL 1DETA 1AQZA 3D5IA 1BRSA 2RBIA 2F56A 1RDSA 1RGCA 1LRAA 1BNEA 1RGLA 1CH0A 3DH2A
chains in the Genus database with same CATH superfamily
1I0VA 1LXEA 2FGTA 3E99A 5HOHA 4FMBA 2HMJB 4HM4B 5BXQA 1JB5A 3S27A 2L4VA 1DMQA 3FF0A 1IQYA 6STDA 1BNSA 4R80A 7GSPA 3X3YA 1N9JA 2GU3A 3G0KA 1RLSA 1YGEA 1JB2A 3PCSA 1TU5A 2OWPA 1MOLA 4J5GA 2ML6A 1BRIA 4RNYA 3D3LA 4XBXA 3Q2PA 1NB5I 1IT7A 3NUVA 2WGQA 1BRKA 2I9WA 4K90B 1DYUA 3ZG0A 1TTOA 1GMRA 5LC6A 1X1UA 1I2EA 1EQKA 2CFKA 1WMPA 2BHMA 2O3OA 1KC84 2IUJA 2R41A 4HAAA 1RN4A 4HVNA 4O02B 5KP1A 3CCE3 3CCS3 1OCVA 2FXTA 2YX9A 3F7SA 3GZBA 1YIJ3 1UI8A 3MG2A 3RGRA 1RGEA 1FGQA 1GY5A 1A67A 3EJVA 2GSPA 1PFPA 2ZL8A 1T2HA 1KD14 1IVUA 1T2IA 1TRPA 2GEXA 3DGYA 4FCMA 2BMRB 2XSHB 6RNTA 4HBRA 3NBRA 1A90A 2STDA 3EBTA 3FG3A 4HZ9B 1M1XB 2IYJA 2RFRA 2WO0A 3AHWA 3BNCA 4EXRA 3WDGB 5G2GA 1X1XA 3DXOA 1QAFA 4L8PA 4RNTA 5HGRA 8RNTA 4NREA 5AIGA 3EC9A 1MNLA 2L1SA 3BLZA 1UCJA 3F40A 1RCLA 1B20A 3I553 3GSPA 2H0IA 4GL6A 2CX1A 1BRHA 1STDA 1W7CA 4J5KA 4O3VA 3CCU3 4GSPA 4HM8B 1IQXA 1BSEA 4N6NB 1N8QA 2O9UX 2P09A 1G0TA 1B3SA 8CHOA 3CMA3 1ISKA 2BU4A 4LZIA 4MEIA 3DY5A 3OWYA 1YVBI 3ALAA 3FCSB 1YI23 4ORLA 4EV2A 2M7OA 1FGOA 2HMKB 2PNCA 3RGAA 3N8BA 1BNGA 1BNFA 1EA2A 1LNIA 1MWRA 1X1YA 3V99A 3EF8A 1IK3A 4LYLB 1UI7A 1UDII 1GOVA 1AVKA 1WTHA 2C11A 3BIRA 3URPA 1O7WB 3KKGA 2SARA 3S5CA 1VQ93 1IU7A 1Q864 1BGSA 1UCKA 1YJW3 2W9PA 3DMCA 2OQEA 3FSDA 2UGIA 3LZAA 3FZWA 1IVXA 2HMLB 4X2OA 1K734 1G96A 1JNQA 2E2UA 3PGBA 1BOXA 3WMDA 5CXOA 2ZHXB 5A0OB 1JBSA 1PY3A 1T3BA 3MYTA 3PXMA 3HIIA 4ILFA 4BU4A 1UW1A 3B8LA 4IT7A 1ROAA 3LOYA 4EBGA 1BVIA 5DREA 1BRJA 3CME3 4HM0B 1JZOA 3AGOA 3K0ZA 4EW5A 3DUKA 1JKGB 1I2GA 1B2XA 1UCLA 1V58A 1UGHI 3GZYB 4K61A 4HM1B 3MKIA 4BTWA 4ZM8A 2Z6BA 2GEYA 1IVWA 5AIIA 2R4IA 1D6UA 1VQ73 2H0HA 3JUNA 3I563 1YJN3 1VQ83 4EV5A 1WNHA 1SIHA 2F56A 1RDSA 2WOHA 1RGCA 1LRAA 3OWSA 4FMDA 4HZBB 5D82A 1Q40B 5TGNA 5CF1A 1TP6A 3FG4A 5EEOA 4EYCA 3LH4A 1JB4A 3EX9A 3FF2A 4KFEA 1Y4KA 4CDLA 4N6V0 4HKVB 1I70A 2HMMB 1SJWA 4TX4A 3HI7A 1FGRA 1I0XA 1N9EA 1C7HA 3OWUA 5STDA 1TJDA 3L0RA 5D81A 5IG5A 1RNBA 4MMZB 1UUWB 1W01A 1IDPA 4XDWA 3H3HA 2YFLB 1B2ZA 4O2HA 1OUNA 3NV0A 7STDA 7RNTA 1BAOA 3U1WA 5DRVA 4WHAA 1FGTA 3IPTA 3J7Yd 1GSPA 2CX0A 3JUMA 4R4KA 4XM4A 1J2BA 1EEJA 2P0MA 3JUOA 3EN8A 2J8XB 3BNDA 4XDVA 5I97A 5ELJA 2Y74A 3CD63 3AMOB 5CLKA 1YVSA 5IENA 3ECFA 3LTBA 1Q42A 4CJNA 1B2SA 2CFLA 1FGMA 1QVF2 2OCTA 2B24B 2D42A 2LYXA 3AHSA 4JRFA 1LOWA 4WP5A 1RTUA 2Q07A 2CC3A 1UUVB 1E3VA 5BU4A 2W03A 3QRDA 1I8VA 3HOHA 1NWWA 2GBWB 3LTCA 1RRHA 3B7CA 1MGWA 2GBXB 3LT9A 3KCHA 4KVHA 4LSOA 1OF5A 3LMLA 1RGGA 3RNTA 4DKIA 2W04A 1O7PB 1WMNA 3F14A 1TIJA 4CPKA 1FA3A 1ZO2A 3OV4A 1I3IA 2CWTA 1GYBA 2E2VA 3UNLA 3MSOA 1K9M4 1FUSA 3MPHA 3KE7A 4RBNA 2F99A 2W2CA 5BIRA 1BSCA 1Z1SA 3FGYA 3Q3FA 4N6UA 3F9SA 3SEDA 1K28A 2V1LA 4JF8A 1Q814 1FW7A 1Q824 3GWRA 1SARA 3WR2A 3PS8A 3VSYA 2PZVA 1DE3A 1N5PA 1QJGA 2W9QA 1LNHA 1STFI 1A2KA 4MMYB 4I4KA 2OOVC 1OHSA 4L7KA 3X3XA 4BIRA 1VQ53 1ULJB 3OXAA 3BNEA 2IY2A 1GOYA 1VQ43 1K8A4 2ML5A 1VQQA 1IVVA 3CNXA 2C10A 3EN1B 1QMAA 3G6E3 2RNTA 2KF6A 3NBBA 3NM2A 4HM6B 1WQLB 1RJOA 1RNTA 3IMAB 4FR9A 1BSDA 3HK4A 2GU1A 3AGNA 1GS3A 1NDOB 5IW9A 4X2HA 2GXFA 1BNRA 3GZRA 3SVAA 4N6TA 4KZ1A 5AI1A 1BSAA 1JV2B 1AVLA 4FMAA 4BTYA 3DGLA 5AYRB 1DETA 4IPBA 2UUGC 3CNMA 3D5IA 3VF1A 2MC8A 2RBIA 2B1XB 3KZTA 1F8NA 5AEWB 5FW5A 4FCZA 5IEOA 1SIIA 2XR8B 1W4NA 4MMXB 1YJ93 1Q7Y4 1VQN3 3NM7A 5CF2A 2KXGA 4KT3B 1EG9B 1RRLA 4O8SA 5IERA 3D4AA 3EB8A 1W2B2 3O8YA 1VQM3 4GHOA 1MWUA 3T8NA 1N5HA 2YFIB 1US1A 2F86B 5JPPA 2A15A 1C54A 2RCDA 3VGNA 1DMMA 3X3ZA 1RGFA 2KAAA 4PEJA 3CC73 2CH9A 3JUPA 3UB1A 1BNIA 4MJDA 5AYSC 3DM8A 1YIT3 4LEHA 1MWTA 5AIFA 3UJMA 2KF5A 1W5ZA 1ZX2A 2BIRA 5FGOA 3ZG5A 2QEX3 3NBJA 3PZWA 2HMOB 2JQ5A 5RNTA 1G02A 3BNBA 1GY6A 3JVCA 2CHCA 1FUWA 1N8R4 1FYSA 1VQL3 3QK9A 1L5GB 5KP4A 1IV7A 1LVNA 2P0XA 1TFKA 4KFDA 4N6LA 5M18A 1VQ63 2CWUA 1GD3A 4H61A 3G713 1JN5B 2F5MA 1SQWA 2WOFA 2XH9A 3EE1A 3LTDA 3V98A 9RNTA 3FH1A 3WOFB 1QVG2 1BUQA 3EBYA 5IG3A 4RNZA 1ZS7A 3CXC2 3GAXA 2P05A 2OTJ3 4AEQA 4XBTA 1ASKA 1BUJA 1JKGA 3KN4A 2IUKA 1RKYA 1VQK3 1JBRA 3Q1CA 4IIAA 4BL3A 1BRGA 4LGQA 3MG1A 1M1K4 2RSXA 2K0MA 1RGKA 4CCVA 1PYLA 4G1MB 2AADA 1M904 1Q40A 3NQYA 5M1AA 3F8HA 1BANA 1YHQ3 1DVDA 1PU4A 2OTL3 2IA7A 2Z76A 3UL5A 3K5TA 3SX1A 2CW9A 1GMPA 3HZPA 2KF3A 1JRQA 5CK6A 1JBTA 1S723 4AKZA 1JN5A 5IG0A 1GD4A 2CG0A 3KSED 2OOVA 3DGOA 3BB9A 3WA3A 3FLJA 2KCDA 3K7CA 4HM7B 2XRXB 3D5GA 1AV4A 1O7GB 4HM5B 3LXUX 1GOUA 1R4YA 1RMSA 4R9LA 5KP3A 5ELUA 3X41A 1KSIA 3LTAA 1OHPA 4N6MA 4FMCA 3V92A 2W56B 3CCQ3 1OACA 1SPUA 1AY7A 3ER7A 3WOEB 3OW22 1RGAA 3F7XA 5GSPA 2CK3H 1D6ZA 4H3UA 1UGIA 2ZA4A 1VZZA 3BU4A 3N9HA 3WHOA 1TUHA 3AMOA 1EUIC 1NB3I 6GSPA 3G4S3 2BNGA 3ROBA 1W00A 2BMOB 3KFQC 4QWTA 3SLUA 1NNVA 3CPOA 4OK0A 4WFOA 1B21A 1ROVA 1W6GA 2JDIH 2BT3A 1AQZA 5EQLA 4WYKB 3D9RA 1JZDA 4NPBA 5BVBA 3CPW2 3GRDA 1CQSA 3KSPA 1BNEA 1VQP3 1W2ZA 1EKMA 2F98A 3DH2A 1IQ8A 1RSNA 1RN7A 1CYVA 1AR0A 1V57A 5G1KA 2W56A 3GZXB 3I0YA 3MG3A 4N6OB 1TFOA 1Q9EA 2BMQB 3CU3A 4HYZA 3MHEA 1E97A 3A76A 3SOYA 1LOXA 1V74A 3N54B 1OGZA 2MF7A 3SXXA 4OVMA 1B2MA 2Z77A 1LQMB 4KFFA 3SYUA 1OH0A 1NO3A 1O7MB 3JUQA 3HX8A 1NU3A 1T5YA 3LT8A 2CFWA 3Q90A 4HM3B 1JJ22 3M8CA 1A2VA 1O7HB 1BIRA 1MGRA 4BTXA 1VQO3 2CIUA 2KRTA 4J9AA 5AEUB 4R1KA 3NHXA 1W6CA 1RHLA 3G8ZA 3WODG 1S5AA 3A5EA 1B27A 4U13A 1ZGXA 1BNJA 3HIGA 1BU4A 1IT8A 3B4OA 2CFDA 1FZUA 2BO9B 4N3VA 4WWUC 1CEWI 4WYKA 5EVHA 4BL2A 3CCJ3 4GB5A 1KQS2 1A2PA 1D6YA 2CKFB 2HMNB 5G1LA 2IMJA 1LQGC 3FKAA 3KIIA 3MWZA 4FCJA 4XBYA 3S28A 1K41A 4HJLB 2QIYA 3CC23 2D1WA 3U97A 1FUTA 1GY7A 3STDA 4R9KA 4HM2B 4STDA 3X42A 1KWIA 3DGMA 2XEPA 3NQZA 1M9GA 1GMQA 4K1UA 3IJEB 2P38A 2XF3A 3D79A 3NXJA 1U8CB 3FG1A 1I2FA 2E2TA 2H0GA 2K3DA 2RGQA 4LMIA 5IG4A 4I5QA 2F5WA 1UUGB 2Z7AA 2ZDJA 2Y73A 1HYFA 1I3FA 1HZ1A 2XFSA 3T0UA 1OGXA 2FNQA 3S29A 1IV9A 1HKXA 2W0QA 4HOHA 1U5OA 3K63A 3WA2X 4RZMA 2XFTA 3NV0B 2YFJB 1O7NB 2KF4A 1Q7HA 2AAEA 3CCR3 2F4YA 1LOYA 5M19A 5D83A 3X40A 4OUQA 2W6JH 4L8OA 3OX9A 3PYJA 3DZLA 1YGWA 2QA43 3ZFZA 3CCM3 2C4BA 2XGLA 2CG1A 1B2UA 3CCL3 1IYYA 1OPYA 1QALA 2CWVA 1DMNA 1UCIA 2XGNA 5JPUA 3EQQB 4K1VA 3CC43 2HOHA 3TDGA 3UL6A 1LOVA 3CCV3 3K9MC 5LC7A 3DGNA 2LQVA 2K54A 1ULIB 1CYUA 2QGUA 1W6YA 1NJI4 1YNVX 2OQEC 2UX0A 3NX0A 4AKYA 1QAKA 5JBSA 2WGOA 3EHCA 1MWSA 3B4PA 1WMOA 3F8XA 3G16A 3LYGA 1RCKA 1R4CA 1RGHA 1E3RA 4XB5A 5IF6A 3S67A 1BSBA 1TRQA 4J8TA 1W02A 3H51A 1RN1A 4NHFA 2XSOB 1X1WA 1OHOA 2INXA 3RDEA 2CFGA 1HU9A 1BRNL 4Q53A 5AIHA 1DVCA 1OF5B 2SBLA 1BRSA 1RGLA 3PCRA 1CH0A 3T8UA 4EC6A 5IEPA 3SOAA
chains in the Genus database with same CATH topology
1RSNA 1I0VA 5HOHA 1I70A 1Q9EA 3D4AA 1I0XA 1BNSA 7GSPA 4GHOA 1RNBA 1RLSA 1B2MA 3SYUA 4J5GA 1C54A 1BRIA 1B2ZA 1RGFA 2KAAA 1BNIA 1BRKA 7RNTA 1BAOA 1GMRA 1TTOA 1X1UA 1I2EA 1BIRA 1MGRA 1RN4A 2KF5A 4HAAA 1GSPA 2BIRA 1RHLA 3A5EA 1B27A 1ZGXA 1BNJA 1G02A 1BU4A 5RNTA 1FZUA 1RGEA 1FYSA 2GSPA 1A2PA 1T2HA 1T2IA 1YVSA 1TRPA 3DGYA 2F5MA 6RNTA 9RNTA 1B2SA 3AHWA 3AHSA 1FUTA 1LOWA 1X1XA 1RTUA 4RNTA 8RNTA 5BU4A 1BUJA 1UCJA 1GMQA 1I8VA 3HOHA 1RCLA 1B20A 1I2FA 3GSPA 1MGWA 1JBRA 1BRHA 4J5KA 1BRGA 3KCHA 4GSPA 1BSEA 2F5WA 1RGGA 1B3SA 3RNTA 1RGKA 1HYFA 1I3FA 1HZ1A 1PYLA 2BU4A 2AADA 1BANA 1I3IA 4HOHA 1FUSA 1GMPA 2KF4A 1BNGA 1BNFA 1LNIA 1X1YA 2AAEA 2KF3A 1JBTA 5BIRA 1BSCA 2F4YA 1LOYA 3Q3FA 1GOVA 3BIRA 3URPA 1FW7A 3D5GA 1SARA 3WR2A 1DE3A 2SARA 1YGWA 1GOUA 1R4YA 1RMSA 2C4BA 1BGSA 1UCKA 1B2UA 1IYYA 4BIRA 1UCIA 1BOXA 1GOYA 1AY7A 2HOHA 1JBSA 1LOVA 2RNTA 1RGAA 2KF6A 1PY3A 5GSPA 4BU4A 1RNTA 1BSDA 1YNVX 3AGNA 2ZA4A 3BU4A 1BVIA 1BRJA 3WHOA 1RCKA 1RGHA 3AGOA 6GSPA 1BNRA 1BSBA 1BSAA 1I2GA 1TRQA 1B2XA 1RN1A 1UCLA 1X1WA 1B21A 1BRNL 1DETA 1AQZA 3D5IA 1BRSA 2RBIA 2F56A 1RDSA 1RGCA 1LRAA 1BNEA 1RGLA 1CH0A 3DH2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RSN A;  1I0V A;  5HOH A;  1I70 A;  1Q9E A;  3D4A A;  1I0X A;  1BNS A;  7GSP A;  4GHO A;  1RNB A;  1RLS A;  1B2M A;  3SYU A;  4J5G A;  1C54 A;  1BRI A;  1B2Z A;  1RGF A;  2KAA A;  1BNI A;  1BRK A;  7RNT A;  1BAO A;  1GMR A;  1TTO A;  1X1U A;  1I2E A;  1BIR A;  1MGR A;  1RN4 A;  2KF5 A;  4HAA A;  1GSP A;  2BIR A;  1RHL A;  3A5E A;  1B27 A;  1ZGX A;  1BNJ A;  1G02 A;  1BU4 A;  5RNT A;  1FZU A;  1RGE A;  1FYS A;  2GSP A;  1A2P A;  1T2H A;  1T2I A;  1YVS A;  1TRP A;  3DGY A;  2F5M A;  6RNT A;  9RNT A;  1B2S A;  3AHW A;  3AHS A;  1FUT A;  1LOW A;  1X1X A;  1RTU A;  4RNT A;  8RNT A;  5BU4 A;  1BUJ A;  1UCJ A;  1GMQ A;  1I8V A;  3HOH A;  1RCL A;  1B20 A;  1I2F A;  3GSP A;  1MGW A;  1JBR A;  1BRH A;  4J5K A;  1BRG A;  3KCH A;  4GSP A;  1BSE A;  2F5W A;  1RGG A;  1B3S A;  3RNT A;  1RGK A;  1HYF A;  1I3F A;  1HZ1 A;  1PYL A;  2BU4 A;  2AAD A;  1BAN A;  1I3I A;  4HOH A;  1FUS A;  1GMP A;  2KF4 A;  1BNG A;  1BNF A;  1LNI A;  1X1Y A;  2AAE A;  2KF3 A;  1JBT A;  5BIR A;  1BSC A;  2F4Y A;  1LOY A;  3Q3F A;  1GOV A;  3BIR A;  3URP A;  1FW7 A;  3D5G A;  1SAR A;  3WR2 A;  1DE3 A;  2SAR A;  1YGW A;  1GOU A;  1R4Y A;  1RMS A;  2C4B A;  1BGS A;  1UCK A;  1B2U A;  1IYY A;  4BIR A;  1UCI A;  1BOX A;  1GOY A;  1AY7 A;  2HOH A;  1JBS A;  1LOV A;  2RNT A;  1RGA A;  2KF6 A;  1PY3 A;  5GSP A;  4BU4 A;  1RNT A;  1BSD A;  1YNV X;  3AGN A;  2ZA4 A;  3BU4 A;  1BVI A;  1BRJ A;  3WHO A;  1RCK A;  1RGH A;  3AGO A;  6GSP A;  1BNR A;  1BSB A;  1BSA A;  1I2G A;  1TRQ A;  1B2X A;  1RN1 A;  1UCL A;  1X1W A;  1B21 A;  1BRN L;  1DET A;  1AQZ A;  3D5I A;  1BRS A;  2RBI A;  2F56 A;  1RDS A;  1RGC A;  1LRA A;  1BNE A;  1RGL A;  1CH0 A;  3DH2 A; 
#chains in the Genus database with same CATH topology
 1I0V A;  1LXE A;  2FGT A;  3E99 A;  5HOH A;  4FMB A;  2HMJ B;  4HM4 B;  5BXQ A;  1JB5 A;  3S27 A;  2L4V A;  1DMQ A;  3FF0 A;  1IQY A;  6STD A;  1BNS A;  4R80 A;  7GSP A;  3X3Y A;  1N9J A;  2GU3 A;  3G0K A;  1RLS A;  1YGE A;  1JB2 A;  3PCS A;  1TU5 A;  2OWP A;  1MOL A;  4J5G A;  2ML6 A;  1BRI A;  4RNY A;  3D3L A;  4XBX A;  3Q2P A;  1NB5 I;  1IT7 A;  3NUV A;  2WGQ A;  1BRK A;  2I9W A;  4K90 B;  1DYU A;  3ZG0 A;  1TTO A;  1GMR A;  5LC6 A;  1X1U A;  1I2E A;  1EQK A;  2CFK A;  1WMP A;  2BHM A;  2O3O A;  1KC8 4;  2IUJ A;  2R41 A;  4HAA A;  1RN4 A;  4HVN A;  4O02 B;  5KP1 A;  3CCE 3;  3CCS 3;  1OCV A;  2FXT A;  2YX9 A;  3F7S A;  3GZB A;  1YIJ 3;  1UI8 A;  3MG2 A;  3RGR A;  1RGE A;  1FGQ A;  1GY5 A;  1A67 A;  3EJV A;  2GSP A;  1PFP A;  2ZL8 A;  1T2H A;  1KD1 4;  1IVU A;  1T2I A;  1TRP A;  2GEX A;  3DGY A;  4FCM A;  2BMR B;  2XSH B;  6RNT A;  4HBR A;  3NBR A;  1A90 A;  2STD A;  3EBT A;  3FG3 A;  4HZ9 B;  1M1X B;  2IYJ A;  2RFR A;  2WO0 A;  3AHW A;  3BNC A;  4EXR A;  3WDG B;  5G2G A;  1X1X A;  3DXO A;  1QAF A;  4L8P A;  4RNT A;  5HGR A;  8RNT A;  4NRE A;  5AIG A;  3EC9 A;  1MNL A;  2L1S A;  3BLZ A;  1UCJ A;  3F40 A;  1RCL A;  1B20 A;  3I55 3;  3GSP A;  2H0I A;  4GL6 A;  2CX1 A;  1BRH A;  1STD A;  1W7C A;  4J5K A;  4O3V A;  3CCU 3;  4GSP A;  4HM8 B;  1IQX A;  1BSE A;  4N6N B;  1N8Q A;  2O9U X;  2P09 A;  1G0T A;  1B3S A;  8CHO A;  3CMA 3;  1ISK A;  2BU4 A;  4LZI A;  4MEI A;  3DY5 A;  3OWY A;  1YVB I;  3ALA A;  3FCS B;  1YI2 3;  4ORL A;  4EV2 A;  2M7O A;  1FGO A;  2HMK B;  2PNC A;  3RGA A;  3N8B A;  1BNG A;  1BNF A;  1EA2 A;  1LNI A;  1MWR A;  1X1Y A;  3V99 A;  3EF8 A;  1IK3 A;  4LYL B;  1UI7 A;  1UDI I;  1GOV A;  1AVK A;  1WTH A;  2C11 A;  3BIR A;  3URP A;  1O7W B;  3KKG A;  2SAR A;  3S5C A;  1VQ9 3;  1IU7 A;  1Q86 4;  1BGS A;  1UCK A;  1YJW 3;  2W9P A;  3DMC A;  2OQE A;  3FSD A;  2UGI A;  3LZA A;  3FZW A;  1IVX A;  2HML B;  4X2O A;  1K73 4;  1G96 A;  1JNQ A;  2E2U A;  3PGB A;  1BOX A;  3WMD A;  5CXO A;  2ZHX B;  5A0O B;  1JBS A;  1PY3 A;  1T3B A;  3MYT A;  3PXM A;  3HII A;  4ILF A;  4BU4 A;  1UW1 A;  3B8L A;  4IT7 A;  1ROA A;  3LOY A;  4EBG A;  1BVI A;  5DRE A;  1BRJ A;  3CME 3;  4HM0 B;  1JZO A;  3AGO A;  3K0Z A;  4EW5 A;  3DUK A;  1JKG B;  1I2G A;  1B2X A;  1UCL A;  1V58 A;  1UGH I;  3GZY B;  4K61 A;  4HM1 B;  3MKI A;  4BTW A;  4ZM8 A;  2Z6B A;  2GEY A;  1IVW A;  5AII A;  2R4I A;  1D6U A;  1VQ7 3;  2H0H A;  3JUN A;  3I56 3;  1YJN 3;  1VQ8 3;  4EV5 A;  1WNH A;  1SIH A;  2F56 A;  1RDS A;  2WOH A;  1RGC A;  1LRA A;  3OWS A;  4FMD A;  4HZB B;  5D82 A;  1Q40 B;  5TGN A;  5CF1 A;  1TP6 A;  3FG4 A;  5EEO A;  4EYC A;  3LH4 A;  1JB4 A;  3EX9 A;  3FF2 A;  4KFE A;  1Y4K A;  4CDL A;  4N6V 0;  4HKV B;  1I70 A;  2HMM B;  1SJW A;  4TX4 A;  3HI7 A;  1FGR A;  1I0X A;  1N9E A;  1C7H A;  3OWU A;  5STD A;  1TJD A;  3L0R A;  5D81 A;  5IG5 A;  1RNB A;  4MMZ B;  1UUW B;  1W01 A;  1IDP A;  4XDW A;  3H3H A;  2YFL B;  1B2Z A;  4O2H A;  1OUN A;  3NV0 A;  7STD A;  7RNT A;  1BAO A;  3U1W A;  5DRV A;  4WHA A;  1FGT A;  3IPT A;  3J7Y d;  1GSP A;  2CX0 A;  3JUM A;  4R4K A;  4XM4 A;  1J2B A;  1EEJ A;  2P0M A;  3JUO A;  3EN8 A;  2J8X B;  3BND A;  4XDV A;  5I97 A;  5ELJ A;  2Y74 A;  3CD6 3;  3AMO B;  5CLK A;  1YVS A;  5IEN A;  3ECF A;  3LTB A;  1Q42 A;  4CJN A;  1B2S A;  2CFL A;  1FGM A;  1QVF 2;  2OCT A;  2B24 B;  2D42 A;  2LYX A;  3AHS A;  4JRF A;  1LOW A;  4WP5 A;  1RTU A;  2Q07 A;  2CC3 A;  1UUV B;  1E3V A;  5BU4 A;  2W03 A;  3QRD A;  1I8V A;  3HOH A;  1NWW A;  2GBW B;  3LTC A;  1RRH A;  3B7C A;  1MGW A;  2GBX B;  3LT9 A;  3KCH A;  4KVH A;  4LSO A;  1OF5 A;  3LML A;  1RGG A;  3RNT A;  4DKI A;  2W04 A;  1O7P B;  1WMN A;  3F14 A;  1TIJ A;  4CPK A;  1FA3 A;  1ZO2 A;  3OV4 A;  1I3I A;  2CWT A;  1GYB A;  2E2V A;  3UNL A;  3MSO A;  1K9M 4;  1FUS A;  3MPH A;  3KE7 A;  4RBN A;  2F99 A;  2W2C A;  5BIR A;  1BSC A;  1Z1S A;  3FGY A;  3Q3F A;  4N6U A;  3F9S A;  3SED A;  1K28 A;  2V1L A;  4JF8 A;  1Q81 4;  1FW7 A;  1Q82 4;  3GWR A;  1SAR A;  3WR2 A;  3PS8 A;  3VSY A;  2PZV A;  1DE3 A;  1N5P A;  1QJG A;  2W9Q A;  1LNH A;  1STF I;  1A2K A;  4MMY B;  4I4K A;  2OOV C;  1OHS A;  4L7K A;  3X3X A;  4BIR A;  1VQ5 3;  1ULJ B;  3OXA A;  3BNE A;  2IY2 A;  1GOY A;  1VQ4 3;  1K8A 4;  2ML5 A;  1VQQ A;  1IVV A;  3CNX A;  2C10 A;  3EN1 B;  1QMA A;  3G6E 3;  2RNT A;  2KF6 A;  3NBB A;  3NM2 A;  4HM6 B;  1WQL B;  1RJO A;  1RNT A;  3IMA B;  4FR9 A;  1BSD A;  3HK4 A;  2GU1 A;  3AGN A;  1GS3 A;  1NDO B;  5IW9 A;  4X2H A;  2GXF A;  1BNR A;  3GZR A;  3SVA A;  4N6T A;  4KZ1 A;  5AI1 A;  1BSA A;  1JV2 B;  1AVL A;  4FMA A;  4BTY A;  3DGL A;  5AYR B;  1DET A;  4IPB A;  2UUG C;  3CNM A;  3D5I A;  3VF1 A;  2MC8 A;  2RBI A;  2B1X B;  3KZT A;  1F8N A;  5AEW B;  5FW5 A;  4FCZ A;  5IEO A;  1SII A;  2XR8 B;  1W4N A;  4MMX B;  1YJ9 3;  1Q7Y 4;  1VQN 3;  3NM7 A;  5CF2 A;  2KXG A;  4KT3 B;  1EG9 B;  1RRL A;  4O8S A;  5IER A;  3D4A A;  3EB8 A;  1W2B 2;  3O8Y A;  1VQM 3;  4GHO A;  1MWU A;  3T8N A;  1N5H A;  2YFI B;  1US1 A;  2F86 B;  5JPP A;  2A15 A;  1C54 A;  2RCD A;  3VGN A;  1DMM A;  3X3Z A;  1RGF A;  2KAA A;  4PEJ A;  3CC7 3;  2CH9 A;  3JUP A;  3UB1 A;  1BNI A;  4MJD A;  5AYS C;  3DM8 A;  1YIT 3;  4LEH A;  1MWT A;  5AIF A;  3UJM A;  2KF5 A;  1W5Z A;  1ZX2 A;  2BIR A;  5FGO A;  3ZG5 A;  2QEX 3;  3NBJ A;  3PZW A;  2HMO B;  2JQ5 A;  5RNT A;  1G02 A;  3BNB A;  1GY6 A;  3JVC A;  2CHC A;  1FUW A;  1N8R 4;  1FYS A;  1VQL 3;  3QK9 A;  1L5G B;  5KP4 A;  1IV7 A;  1LVN A;  2P0X A;  1TFK A;  4KFD A;  4N6L A;  5M18 A;  1VQ6 3;  2CWU A;  1GD3 A;  4H61 A;  3G71 3;  1JN5 B;  2F5M A;  1SQW A;  2WOF A;  2XH9 A;  3EE1 A;  3LTD A;  3V98 A;  9RNT A;  3FH1 A;  3WOF B;  1QVG 2;  1BUQ A;  3EBY A;  5IG3 A;  4RNZ A;  1ZS7 A;  3CXC 2;  3GAX A;  2P05 A;  2OTJ 3;  4AEQ A;  4XBT A;  1ASK A;  1BUJ A;  1JKG A;  3KN4 A;  2IUK A;  1RKY A;  1VQK 3;  1JBR A;  3Q1C A;  4IIA A;  4BL3 A;  1BRG A;  4LGQ A;  3MG1 A;  1M1K 4;  2RSX A;  2K0M A;  1RGK A;  4CCV A;  1PYL A;  4G1M B;  2AAD A;  1M90 4;  1Q40 A;  3NQY A;  5M1A A;  3F8H A;  1BAN A;  1YHQ 3;  1DVD A;  1PU4 A;  2OTL 3;  2IA7 A;  2Z76 A;  3UL5 A;  3K5T A;  3SX1 A;  2CW9 A;  1GMP A;  3HZP A;  2KF3 A;  1JRQ A;  5CK6 A;  1JBT A;  1S72 3;  4AKZ A;  1JN5 A;  5IG0 A;  1GD4 A;  2CG0 A;  3KSE D;  2OOV A;  3DGO A;  3BB9 A;  3WA3 A;  3FLJ A;  2KCD A;  3K7C A;  4HM7 B;  2XRX B;  3D5G A;  1AV4 A;  1O7G B;  4HM5 B;  3LXU X;  1GOU A;  1R4Y A;  1RMS A;  4R9L A;  5KP3 A;  5ELU A;  3X41 A;  1KSI A;  3LTA A;  1OHP A;  4N6M A;  4FMC A;  3V92 A;  2W56 B;  3CCQ 3;  1OAC A;  1SPU A;  1AY7 A;  3ER7 A;  3WOE B;  3OW2 2;  1RGA A;  3F7X A;  5GSP A;  2CK3 H;  1D6Z A;  4H3U A;  1UGI A;  2ZA4 A;  1VZZ A;  3BU4 A;  3N9H A;  3WHO A;  1TUH A;  3AMO A;  1EUI C;  1NB3 I;  6GSP A;  3G4S 3;  2BNG A;  3ROB A;  1W00 A;  2BMO B;  3KFQ C;  4QWT A;  3SLU A;  1NNV A;  3CPO A;  4OK0 A;  4WFO A;  1B21 A;  1ROV A;  1W6G A;  2JDI H;  2BT3 A;  1AQZ A;  5EQL A;  4WYK B;  3D9R A;  1JZD A;  4NPB A;  5BVB A;  3CPW 2;  3GRD A;  1CQS A;  3KSP A;  1BNE A;  1VQP 3;  1W2Z A;  1EKM A;  2F98 A;  3DH2 A;  1IQ8 A;  1RSN A;  1RN7 A;  1CYV A;  1AR0 A;  1V57 A;  5G1K A;  2W56 A;  3GZX B;  3I0Y A;  3MG3 A;  4N6O B;  1TFO A;  1Q9E A;  2BMQ B;  3CU3 A;  4HYZ A;  3MHE A;  1E97 A;  3A76 A;  3SOY A;  1LOX A;  1V74 A;  3N54 B;  1OGZ A;  2MF7 A;  3SXX A;  4OVM A;  1B2M A;  2Z77 A;  1LQM B;  4KFF A;  3SYU A;  1OH0 A;  1NO3 A;  1O7M B;  3JUQ A;  3HX8 A;  1NU3 A;  1T5Y A;  3LT8 A;  2CFW A;  3Q90 A;  4HM3 B;  1JJ2 2;  3M8C A;  1A2V A;  1O7H B;  1BIR A;  1MGR A;  4BTX A;  1VQO 3;  2CIU A;  2KRT A;  4J9A A;  5AEU B;  4R1K A;  3NHX A;  1W6C A;  1RHL A;  3G8Z A;  3WOD G;  1S5A A;  3A5E A;  1B27 A;  4U13 A;  1ZGX A;  1BNJ A;  3HIG A;  1BU4 A;  1IT8 A;  3B4O A;  2CFD A;  1FZU A;  2BO9 B;  4N3V A;  4WWU C;  1CEW I;  4WYK A;  5EVH A;  4BL2 A;  3CCJ 3;  4GB5 A;  1KQS 2;  1A2P A;  1D6Y A;  2CKF B;  2HMN B;  5G1L A;  2IMJ A;  1LQG C;  3FKA A;  3KII A;  3MWZ A;  4FCJ A;  4XBY A;  3S28 A;  1K41 A;  4HJL B;  2QIY A;  3CC2 3;  2D1W A;  3U97 A;  1FUT A;  1GY7 A;  3STD A;  4R9K A;  4HM2 B;  4STD A;  3X42 A;  1KWI A;  3DGM A;  2XEP A;  3NQZ A;  1M9G A;  1GMQ A;  4K1U A;  3IJE B;  2P38 A;  2XF3 A;  3D79 A;  3NXJ A;  1U8C B;  3FG1 A;  1I2F A;  2E2T A;  2H0G A;  2K3D A;  2RGQ A;  4LMI A;  5IG4 A;  4I5Q A;  2F5W A;  1UUG B;  2Z7A A;  2ZDJ A;  2Y73 A;  1HYF A;  1I3F A;  1HZ1 A;  2XFS A;  3T0U A;  1OGX A;  2FNQ A;  3S29 A;  1IV9 A;  1HKX A;  2W0Q A;  4HOH A;  1U5O A;  3K63 A;  3WA2 X;  4RZM A;  2XFT A;  3NV0 B;  2YFJ B;  1O7N B;  2KF4 A;  1Q7H A;  2AAE A;  3CCR 3;  2F4Y A;  1LOY A;  5M19 A;  5D83 A;  3X40 A;  4OUQ A;  2W6J H;  4L8O A;  3OX9 A;  3PYJ A;  3DZL A;  1YGW A;  2QA4 3;  3ZFZ A;  3CCM 3;  2C4B A;  2XGL A;  2CG1 A;  1B2U A;  3CCL 3;  1IYY A;  1OPY A;  1QAL A;  2CWV A;  1DMN A;  1UCI A;  2XGN A;  5JPU A;  3EQQ B;  4K1V A;  3CC4 3;  2HOH A;  3TDG A;  3UL6 A;  1LOV A;  3CCV 3;  3K9M C;  5LC7 A;  3DGN A;  2LQV A;  2K54 A;  1ULI B;  1CYU A;  2QGU A;  1W6Y A;  1NJI 4;  1YNV X;  2OQE C;  2UX0 A;  3NX0 A;  4AKY A;  1QAK A;  5JBS A;  2WGO A;  3EHC A;  1MWS A;  3B4P A;  1WMO A;  3F8X A;  3G16 A;  3LYG A;  1RCK A;  1R4C A;  1RGH A;  1E3R A;  4XB5 A;  5IF6 A;  3S67 A;  1BSB A;  1TRQ A;  4J8T A;  1W02 A;  3H51 A;  1RN1 A;  4NHF A;  2XSO B;  1X1W A;  1OHO A;  2INX A;  3RDE A;  2CFG A;  1HU9 A;  1BRN L;  4Q53 A;  5AIH A;  1DVC A;  1OF5 B;  2SBL A;  1BRS A;  1RGL A;  3PCR A;  1CH0 A;  3T8U A;  4EC6 A;  5IEP A;  3SOA A; 
#chains in the Genus database with same CATH homology
 1RSN A;  1I0V A;  5HOH A;  1I70 A;  1Q9E A;  3D4A A;  1I0X A;  1BNS A;  7GSP A;  4GHO A;  1RNB A;  1RLS A;  1B2M A;  3SYU A;  4J5G A;  1C54 A;  1BRI A;  1B2Z A;  1RGF A;  2KAA A;  1BNI A;  1BRK A;  7RNT A;  1BAO A;  1GMR A;  1TTO A;  1X1U A;  1I2E A;  1BIR A;  1MGR A;  1RN4 A;  2KF5 A;  4HAA A;  1GSP A;  2BIR A;  1RHL A;  3A5E A;  1B27 A;  1ZGX A;  1BNJ A;  1G02 A;  1BU4 A;  5RNT A;  1FZU A;  1RGE A;  1FYS A;  2GSP A;  1A2P A;  1T2H A;  1T2I A;  1YVS A;  1TRP A;  3DGY A;  2F5M A;  6RNT A;  9RNT A;  1B2S A;  3AHW A;  3AHS A;  1FUT A;  1LOW A;  1X1X A;  1RTU A;  4RNT A;  8RNT A;  5BU4 A;  1BUJ A;  1UCJ A;  1GMQ A;  1I8V A;  3HOH A;  1RCL A;  1B20 A;  1I2F A;  3GSP A;  1MGW A;  1JBR A;  1BRH A;  4J5K A;  1BRG A;  3KCH A;  4GSP A;  1BSE A;  2F5W A;  1RGG A;  1B3S A;  3RNT A;  1RGK A;  1HYF A;  1I3F A;  1HZ1 A;  1PYL A;  2BU4 A;  2AAD A;  1BAN A;  1I3I A;  4HOH A;  1FUS A;  1GMP A;  2KF4 A;  1BNG A;  1BNF A;  1LNI A;  1X1Y A;  2AAE A;  2KF3 A;  1JBT A;  5BIR A;  1BSC A;  2F4Y A;  1LOY A;  3Q3F A;  1GOV A;  3BIR A;  3URP A;  1FW7 A;  3D5G A;  1SAR A;  3WR2 A;  1DE3 A;  2SAR A;  1YGW A;  1GOU A;  1R4Y A;  1RMS A;  2C4B A;  1BGS A;  1UCK A;  1B2U A;  1IYY A;  4BIR A;  1UCI A;  1BOX A;  1GOY A;  1AY7 A;  2HOH A;  1JBS A;  1LOV A;  2RNT A;  1RGA A;  2KF6 A;  1PY3 A;  5GSP A;  4BU4 A;  1RNT A;  1BSD A;  1YNV X;  3AGN A;  2ZA4 A;  3BU4 A;  1BVI A;  1BRJ A;  3WHO A;  1RCK A;  1RGH A;  3AGO A;  6GSP A;  1BNR A;  1BSB A;  1BSA A;  1I2G A;  1TRQ A;  1B2X A;  1RN1 A;  1UCL A;  1X1W A;  1B21 A;  1BRN L;  1DET A;  1AQZ A;  3D5I A;  1BRS A;  2RBI A;  2F56 A;  1RDS A;  1RGC A;  1LRA A;  1BNE A;  1RGL A;  1CH0 A;  3DH2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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