2A9UA

Structure of the n-terminal domain of human ubiquitin carboxyl-terminal hydrolase 8 (usp8)
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
134
structure length
134
Chain Sequence
SVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAYVLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRKKLEEKDRQEEAQRLQQKRQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8).
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Ubiquitin carboxyl-terminal hydrolase 8
total genus 56
structure length 134
sequence length 134
chains with identical sequence B
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2005-07-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08969 USP8_dimer USP8 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.58.280 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase; Chain G, domain 1 Hypothetical protein 1500032h18. 2a9uA01
3K1SA 2JQ9A 4U7IA 1WR0A 4CN6A 3ZSTA 4ZEYA 4U2ZA 2CPTA 2W2UA 3ZT6A 3ZSSA 5FVKA 5CGMA 2LRLA 2LRKA 2WWVA 2DL1A 4IT4A 4WZXA 2JQHA 3ZT5A 4CN4A 5CJ5A 4P1NA 4U3CA 1YXRA 3EABA 5LB7B 2JQKA 1WCRA 2K3WA 2V6YA 2CRBA 2V6XA 4U2YA 3ZT7A 4NIQA 2V6YB 4U33A 4U31A 4A5XA 2WY2A 2MPKA 2RPAA 2XZEA 5FVLA 4CN1A 4U7YA 1WFDA 2A9UA
chains in the Genus database with same CATH superfamily
3O1JA 3RYHE 4JEHB 2LRLA 2KLQA 2XQ3A 2PTFA 2VL0A 5KMGP 2Q9QB 2R6GF 2VKHA 1S35A 3UU5A 4YJ3E 4U2YA 3NWIA 1MNDA 5JDNA 3ZCIA 4C90A 3RF1A 2CPTA 2X68A 2BVLA 3NRYA 2WWUA 1WCRA 4AI6A 3Q5DA 3DTOA 2WAUA 3CVRA 3OVUA 1T72A 2JRKA 3RGLA 3VKHA 2XHEB 5FXXA 2A2FX 4WW0A 3RYCE 1KFYA 5JDHA 1IZNB 2W62A 2X9YA 3KDSE 3SOLA 2JIWA 2EHOA 4O4LE 4X1KE 4DNDA 3N2GE 5JR9C 2LE8A 1G73A 1SE7A 3VHLA 1LVKA 4EYUA 1Z0PA 1O3XA 3ZYLA 4EEDA 2XQ4A 2BG9A 3L09A 5IHYA 5AQIB 2Y8DA 1LRZA 4ZHQE 3RIAA 3KFWX 2ZM2A 2WSSV 3RKGA 5LGNB 4CI1B 3T8OA 2Y6XA 1UK5A 4O4IE 2YDRA 2UXXB 3UU6A 2M67A 4WYVA 4BJMA 4IREA 1D1BA 4HWIB 4XBFB 5FMNA 3B5MA 5ADXL 1NEKA 3I0QA 3U78A 2NTYA 4ZI7E 1H7CA 2DWGA 2WB5A 1MMNA 3A7MA 2PG8A 1J1JA 5FXZA 3UT5E 5CB4E 5HXEA 2MAWA 3QNUA 3AVSA 4AKIA 4XAXB 4HWFA 4QH1A 4ILCA 4X1IE 5KX5E 2HPLA 3VKGA 3L39A 4KBMB 5BR8T 5CFBA 5HXHA 2UUBT 4QXBB 1ZHCA 5J2TE 4LF5T 4B3RT 2XAQB 2V6XA 3RX6A 2WZHA 3F57A 3WI3A 2L9QA 4LMKA 3C51A 1BR0A 3KBUA 4QKNA 4DUYT 4QXHB 3AEDA 3AEGA 4EV6A 2I59A 2XASB 1YW0A 2IW5B 2XAHB 2LSYA 2GK9A 2VVNA 5L3CB 1L0VA 4TWHA 2CHNA 1OWAA 4HFDA 1UX4A 4P1NA 5LMNT 1MIYA 2XUEA 5EK3A 4KMCA 3ZKRA 5J0ZA 1XNQT 1SHZC 3HKDE 3RIUC 2XAFB 2C5KT 3UFGA 2X67A 2NR4A 3Q5XA 2X51A 1M7KA 2Q9QD 3PUXF 1OEDC 3AVRA 4A98A 2UUAT 4IDOA 2V6YB 4ISTA 2ZM6T 3ANWB 2WZIA 3KV9A 2DI4A 3FHNA 4O2BE 5IUXA 2UXCT 3OBVE 4IE0A 4AISA 2KMFA 4F8HA 1HNZT 2WCAA 2NW7A 2CXLA 5FL1A 3CKDA 1OEDE 2WU5A 3AE3A 5FY0A 4CN6A 2LOPA 5HEHA 2J1DG 2MOZA 3L3PA 3PTRB 3J9X1 2CBJA 4UR9A 4BJNA 4JI1T 2Q9QA 3ZT5A 2K9AA 1XNRT 4DV0T 4JI0T 3RKOA 3HKCE 1HCIA 2ES0A 4JBWF 3O1IA 1WYCA 4DV4T 3AAIA 3RI5A 5F8PA 3RC3A 4H63V 5JH7E 2V26A 3PUYF 4A56A 2J4GA 5JDGA 2EHOB 2LLYA 3L8RA 3MJXA 2CCQA 4X62T 3CQXC 1MIVA 2XM1A 3FBLA 5AQSB 3LSVA 3RC8A 1Y64B 3RHWA 5ETWA 3DP7A 4DR2T 1US7B 2NWBA 4QWNB 2BG9B 3KVAA 2CEAA 4IDNA 4ILAA 2NW9A 4HWCA 2H88A 3AB3B 3JC6D 4IL4A 3N9QA 3JCFA 3QK6A 3X1DA 3AEEA 2QRXA 2X9HA 3PU3A 4OX9T 1HTJF 3LFMA 4UELA 4ZZCA 2VVSA 3CMLA 5HCJA 1MIWA 5LJNA 4CXYA 3CPZA 2WU2A 5JDLA 4NUUA 1KNPA 3D0TA 2IUBA 2KXPB 4UXNB 2V7IA 3UU4A 4WBNE 1YD8G 4G2AA 3NVOA 2W0GA 2V5DA 5HWXA 4WZXA 3FBZA 3KV4A 2W66A 1VCSA 1N36T 3A5XA 5AQMB 3ONXA 2DLRA 2BS3A 2D2SA 3GMIA 4HWHA 5AQVB 3RQUA 1KEYA 4U31A 4ANJA 3CQGB 4LF6T 4DV3T 3PDYA 2X0YA 2W4XA 2WWVA 3NKZA 3H3AA 4AKLA 4KHZF 1KF6A 2E5VA 5LB7B 3O1HA 4EEBA 4AQFA 4P09A 2HN1A 4JV5T 2C0SA 4EGWA 3R84B 4LF4T 2E9XC 4ZI2D 2WM9A 1LVFA 4J2CA 4IT4A 3GN5A 1XMQT 2ZM0A 3ZC0A 4E7ZA 3N9LA 4P0AA 5FXWA 5FL0A 1G8XA 4YLHA 4PK6A 3O4XE 3E22E 2IIUA 4CXWA 4ZXLA 5AQRB 2LM2A 2XM2A 3K3OA 5LP6E 2VASA 2YDSA 3K3QC 5L4EA 1IBMT 1YKEB 5LA6E 3ONJA 2VKOA 3ZMVB 4X1YE 3UUNA 2BKPA 3HA4A 2Z6EA 3VRAA 3C50A 4NXMT 3UUXB 3N9NA 4KX6A 4U7IA 3FZHB 1DU2A 3S4UA 4IE5A 5F3JA 3QB5K 3N2OA 4WBOA 5JRCA 3PE0A 4FJOA 3E0ZA 2EHOD 4JYAT 3AECA 3CIRA 2D0TA 4JI8T 4ZI3D 3N9MA 2K5BB 3ZT6A 2LRKA 3ESLA 3KV6A 5LJMA 3C98B 3P4QA 4V1Av 4AXPA 5LBMA 2BVMA 3VR9A 4DR3T 3C4ZA 3AE2A 2E5LT 2V7LA 2MPKA 1VOMA 4GK0E 1XDOA 4DR7T 3AEAA 2XQAA 2ACZA 2JMHA 4ILBA 1LKXA 1BR2A 1WYBA 3P7IA 4LF8T 3TLSA 4EB6E 3UFEA 3MK7C 3HL6A 4AQYT 2I0MA 4AKRB 4DV1T 3I9YA 2PJQA 5HCMA 3UTKA 3CQCB 4H9OC 4IIJE 1MMAA 4TZ4C 1SUMB 3PUAA 2VWAA 4ZOLE 4ZEYA 2KZ7B 3V5SA 3V5UA 4IDQA 4EOZB 4LFBT 1R8IA 2UU9T 5FVLA 5HEOA 3HR0A 2FJDA 3OYXA 1HFAA 1NAFA 2MTQA 2MYSA 1T8BA 5AQHB 4PNIA 3E08A 2FJAA 2N9DA 4TNVA 3AEBA 3JAEA 2QA7A 3RQWA 3UQ7A 1D1CA 1XZYA 2LHNA 4GK5E 2XY8B 2G0UA 2VB6A 2KINB 4QX7B 1HG5A 3FXDB 1XMOT 2V7KA 1BR1A 1BR4A 3T1YT 3ZMUB 2VKJA 3SWHA 1HX8A 4YTPA 1I6ZA 1KNRA 5FVKA 3CX6B 3CX7B 4CXXA 2XSAA 4UV9B 2DWKA 4QXCB 2CM0A 4EZ4A 3JC6C 4X66T 3TLTA 3EDUA 2W00A 4GKJT 4O4HE 3ZSTA 5BMVE 5AQNB 4TV8E 4AKHA 3RYFE 5F5WA 3ZCJA 2XQ8A 4OYJA 4Q25A 4CN1A 4UIGA 3OTOT 5ABEA 3Q2MA 2L8KA 2CWOA 3ZEFB 4HEAA 3GN5B 2WQYA 2BZBA 4YSYA 2MBGA 4EAHA 2PBIA 2YKSA 2B1EA 1FJGT 2BKNA 2IMLA 1W09A 1Y01A 3EAMA 3ZSSA 5CGMA 4B3ST 4JI7T 3AE6A 5LCYA 3EUHA 2XPKA 5JDMA 4CI3B 3N9PA 3QOFA 3LBXA 4JI2T 3P4RA 4QX8B 5ABGA 2K24A 4CI2B 2A9UA 3P8CD 3K8PC 2YOEA 4YTMA 2LSGA 2ODVA 3FB2A 2CLYB 4DV5T 2IC9A 2RA1A 3SFDA 5JRCB 3B13A 5ABHA 2OLTA 3MKDA 2W67A 4X64T 1QUUA 4DV7T 4DV2T 4U72A 4I50E 4JI4T 2YN6A 4X5TA 4NXNT 2CE7A 3ETUA 2D9DA 3PUWF 3J7Yq 4ZI2C 2C5JA 4UF0A 2KNDA 4G63A 5KDMC 1XWMA 3ZN1B 4JI6T 4TWFA 3T1HT 2ZM8A 3TLUA 4BAYB 5AFUL 3FZMB 4DMVA 2VQFT 2WDQA 4ISSA 4KUMB 4Z8XA 2HPJA 2XAJB 4HKAA 3P4WA 3RRWA 2BS4A 1VRBA 3EVYA 3TKLB 4GKKT 1HG2A 5JR9A 3VR8A 5E0OA 2Y48B 3ZC1A 1WR0A 1UCUA 3ZLIA 3AE5A 2V7MA 5LMUT 2EHOC 4PK5A 5KXJA 4IE6A 1KNZA 5L3BB 4LMLA 4H9SE 4HFCA 1ZOYA 1FEWA 1WFDA 4CN4A 3UUMA 5M4YA 2DHRA 3AA6B 3RPUA 4PW8A 2BG9C 2JQHA 5L47A 1U4QA 5EK4A 5LG3A 4JEUB 4EZHA 2BS2A 2LT3A 2VKDA 5HYAA 5H6RB 2W63A 2OA5A 4H9QC 1ZKEA 4TN7B 2WS3A 2BDEA 3I9WA 2PFVA 2W2UA 2BG9E 3AE1A 5JTGA 3AAAB 2CRBA 4COFA 4B6XA 2V1DB 2LEHA 4MHCA 2YDQA 4AQGA 2BKOA 2ODUA 5HWYA 1AJ3A 3JAFA 3Q5WA 4I43B 4BA9A 3FZFB 1Z8UA 1UURA 4YHHT 2VQET 3UU3A 4TNWA 3RYIE 3W15B 4CZZB 3WAJA 4ASKA 4IHJE 3N2KE 3DJBA 3OPCA 3O9XA 3EI0A 1HS7A 2LSKA 2JMKA 1FIOA 3HI2A 3TLVA 2BBHA 4DV6T 2FUPA 4A97A 3ZPOA 4U74A 5EZYE 5AQQB 2VK9A 4I0UA 4M1PA 4PAGA 5AQTB 2B76A 3RIUA 2X0LB 3C4XA 3MA9A 2I6HA 2WDRA 4YSXA 4O2AE 3UU8A 3ZJ1A 5FXVA 4DR5T 1V9DA 3LBXB 4Z91A 2XZEA 4Z90A 4OFZA 3LK42 1W0AA 1OEDA 2JQ9A 3PJAA 3F2EA 3H3MA 2OV9A 5DQWA 4QHOA 1D1AA 3GA8A 3AAEB 4O4JE 1WR6A 4LFCT 5ABFA 4HFHA 3R6NA 3ZYKA 2LSIA 3LK3B 2YEVC 5HXRA 4HTEA 2HH7A 4UVCB 1D0ZA 1U5PA 3K3NA 2FBWA 4B3MT 3CWZB 3M3ZB 4H9RC 2XQ9A 5HXSA 2NP9A 4MFRA 3PUZF 5LHGB 5HAXA 5AQFB 2DCFA 4DBRA 4B3TT 2WY2A 4HFEA 4UF0B 3NZPA 4DIDB 2YU1A 1WRDA 5AQJB 5GONE 5JDFA 1VCTA 3UULA 2LM9A 1JNRA 3HKBE 3SFEA 5H6QB 1I94T 1IBKT 4OK0A 4YHJA 4GOUA 3AA1B 2LKHA 2JQQA 2Q9QC 5AQKB 4HGAA 1HF8A 1GQEA 1B7TA 1E1HB 1J5ET 2NOXA 2K48A 5JR9B 2FJBA 2AE9A 3HKEE 3N5LA 3ABVA 3NBXX 3Q5EA 5LBQB 5FYMA 3F31A 4HN9A 4ZS3A 1YQ4A 2J62A 5LHIB 2A3DA 4NUVA 5AQLB 3PURA 5HEJA 5C3JA 1MNEA 4U33A 5AQPB 2NTXA 3H37A 5EK2A 3AA0B 1FMVA 1UX5A 4CQIA 4XZCA 2E2AA 5LOVE 3MZKB 5FY1A 2V5CA 1IJ5A 2CMRA 2JQKA 4JUYA 3IBPA 4UV8B 1HX1B 1QLBA 2LHRA 5AQOB 1J5WA 5C2TA 3SRZA 2H89A 4ZZBA 1NWMX 5IYZE 4LF9T 2XJ7A 2RPAA 3JADA 1HR0T 1SA0E 5L3GB 4LMJA 3IHRA 3LJCA 3BQLA 4PK4A 4DVDA 2UXBT 2E9XD 3AE9A 2IDOB 3G06A 2XAGB 4KHPT 1X79A 4EXTA 5FNVE 4HFIA 4IDPA 1N34T 2AXDS 4L5GA 2C5IT 3NRXA 3KV5A 3BQKA 4H9NC 3B57A 5LNKA 2XQ7A 3RLFF 3ZN0B 5HEUA 3ZMSB 4PJLA 3ZT7A 5L2LA 3CX8B 3M65A 4TUYE 2UXDT 1W9RA 3PV0F 1QSDA 3WAKA 3I1AA 3N9OA 4X20E 2YK0A 2E9XA 1YXRA 2NW8A 4HFVA 3BK9A 3PUQA 4IGUA 4OHFA 4IE7A 1FMWA 3AA7B 1N32T 4L9IA 4JI3T 1OEDB 4EIWA 3OKQA 3C4WA 4OYKA 4AQFC 2H7OA 2VURA 5CJ5A 3SS1A 3RRCA 2DNXA 2SPCA 4U3CA 5FP3A 5ABFB 4K0KT 5LYJE 3I0OA 4DR1T 2D0UA 5A1LA 2HN2A 3AXJA 3VU7H 2M6IA 1X9BA 2WDVA 2CXFA 3U3IA 3QB5A 4ILUA 2CWYA 5JVDE 2QYWA 4TV9E 4MLKA 4PFPA 4MALA 2WMOA 3C64A 3AEFA 4PFOA 2LSJA 2QGSA 3RH3A 3MXZA 2JJ9A 3P50A 3LDQB 1ZEEA 4IDZA 2V7JA 5CA1E 3LK2B 5L3DB 3GWHA 4YTNA 4AKGA 2H7VC 3PJAJ 3NZQA 1JNZA 3AE8A 4TWDA 2XQYA 3FZKB 4LF7T 5LGUB 2CLYC 2UXNB 3IEEA 1M62A 5LGTB 3LG7A 2E8IA 2XTLA 4H9PC 2YU2A 3ZJ2A 3EDVA 2X0HA 4TX5A 3UQ4A 2W61A 4LFAT 2CA5A 4NPPA 4O8SA 5LG4A 4QH4A 4HFBA 4IE4A 2WMNA 1CHUA 4YT0A 2WP9A 1IJ6A 2CBIA 4WNKA 5FKYA 4PJNA 4DUZT 2FJEA 5LXTE 3RIFA 5AQGB 5JDQA 4JI5T 1IBLT 2X9XA 4U7YA 2V8SV 5C8YE 2BBJA 4JLEA 4DR6T 4N78D 1UGOA 4PJJA 1E2AA 3PUVF 5TAOA 2KT9A 4YSZA 2J47A 3UUBA 4ZI3C 3A8YC 2M6BA 1N33T 5AQUB 3CK6A 2XQ6A 5L3FB 2LOSA 1T7SA 5JQGE 4KI0F 3IF8B 4K0UA 4HE8A 3ZYMA 2LKGA 3TLWA 4KP3C 2A72A 5JREA 3EABA 5LHHB 2WBLA 5HXCA 4YFSA 4ZS2A 5L4HA 5DABA 2KWHA 3KVBA 3ONLC 4YJ2E 4C91A 1YQ3A 2VL8A 2P9BA 4DO0A 4QH5A 2JPFA 1W0BA 2DL1A 5CA0E 2X9WA 4YY3T 5DQVA 3VRBA 1ZV4X 5J1GA 2H3RA 3P4PA 2YINA 4DMWA 4I4TE 4NIQA 4F6RC 4UEMA 2F4VT 4AIUA 4HWDA 2IAKA 1MMGA 2IHR1 1OXZA 4FI5A 3KBTA 3MACA 2D5UA 4DBQA 4PJMA 1EZ3A 3IA3A 2KWIB 1HNWT 4H63H 5IWAT 4A5XA 1UUSA 3EHZA 2ACXA 4IL9A 3ZMZB 3K1SA 4ERRA 1ZP0A 3PU8A 3FZLB 4E7SA 4GYSA 4X65T 2IC6A 5FY7A 3QC9A 2E9XB 2HHHT 4GYRA 1NENA 4UVBB 3AE7A 3ZMTB 3AE4A 4GIWA 1MMDA 2N1GA 4MBQA 3ETVA 4U2ZA 5HEGA 3OYZA 3BQIA 1CUNA 1D0YA 3FXEB 2ZMAA 2QVAA 1KK7A 1E7PA 2N2NA 3PUGA 3QUJA 5DJQC 3AXJB 5L3EB 4EYYR 2KSRA 1WLXA 4L0RA 2X66A 3KINB 1XDPA 4ADZA 2LJLA 4UVAB 2ZLYA 4I55E 2CHOA 2CXDA 4P0BA 2XSBA 1YKHB 1HNXT 4YXDA 2UUCT 2L3LA 2XQ5A 3OJAA 1T98A 3Q9DA 4DR4T 2K3WA 2V6YA 3ANWA 1IAPA 2RP4A 5J2UE 1D0XA 3P4SA 3PUSA 1S94A
chains in the Genus database with same CATH topology
3K1SA 2JQ9A 4U7IA 1WR0A 4CN6A 3ZSTA 4ZEYA 4U2ZA 2CPTA 2W2UA 3ZT6A 3ZSSA 5FVKA 5CGMA 2LRLA 2LRKA 2WWVA 2DL1A 4IT4A 4WZXA 2JQHA 3ZT5A 4CN4A 5CJ5A 4P1NA 4U3CA 1YXRA 3EABA 5LB7B 2JQKA 1WCRA 2K3WA 2V6YA 2CRBA 2V6XA 4U2YA 3ZT7A 4NIQA 2V6YB 4U33A 4U31A 4A5XA 2WY2A 2MPKA 2RPAA 2XZEA 5FVLA 4CN1A 4U7YA 1WFDA 2A9UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3K1S A;  2JQ9 A;  4U7I A;  1WR0 A;  4CN6 A;  3ZST A;  4ZEY A;  4U2Z A;  2CPT A;  2W2U A;  3ZT6 A;  3ZSS A;  5FVK A;  5CGM A;  2LRL A;  2LRK A;  2WWV A;  2DL1 A;  4IT4 A;  4WZX A;  2JQH A;  3ZT5 A;  4CN4 A;  5CJ5 A;  4P1N A;  4U3C A;  1YXR A;  3EAB A;  5LB7 B;  2JQK A;  1WCR A;  2K3W A;  2V6Y A;  2CRB A;  2V6X A;  4U2Y A;  3ZT7 A;  4NIQ A;  2V6Y B;  4U33 A;  4U31 A;  4A5X A;  2WY2 A;  2MPK A;  2RPA A;  2XZE A;  5FVL A;  4CN1 A;  4U7Y A;  1WFD A;  2A9U A; 
#chains in the Genus database with same CATH topology
 3O1J A;  3RYH E;  4JEH B;  2LRL A;  2KLQ A;  2XQ3 A;  2PTF A;  2VL0 A;  5KMG P;  2Q9Q B;  2R6G F;  2VKH A;  1S35 A;  3UU5 A;  4YJ3 E;  4U2Y A;  3NWI A;  1MND A;  5JDN A;  3ZCI A;  4C90 A;  3RF1 A;  2CPT A;  2X68 A;  2BVL A;  3NRY A;  2WWU A;  1WCR A;  4AI6 A;  3Q5D A;  3DTO A;  2WAU A;  3CVR A;  3OVU A;  1T72 A;  2JRK A;  3RGL A;  3VKH A;  2XHE B;  5FXX A;  2A2F X;  4WW0 A;  3RYC E;  1KFY A;  5JDH A;  1IZN B;  2W62 A;  2X9Y A;  3KDS E;  3SOL A;  2JIW A;  2EHO A;  4O4L E;  4X1K E;  4DND A;  3N2G E;  5JR9 C;  2LE8 A;  1G73 A;  1SE7 A;  3VHL A;  1LVK A;  4EYU A;  1Z0P A;  1O3X A;  3ZYL A;  4EED A;  2XQ4 A;  2BG9 A;  3L09 A;  5IHY A;  5AQI B;  2Y8D A;  1LRZ A;  4ZHQ E;  3RIA A;  3KFW X;  2ZM2 A;  2WSS V;  3RKG A;  5LGN B;  4CI1 B;  3T8O A;  2Y6X A;  1UK5 A;  4O4I E;  2YDR A;  2UXX B;  3UU6 A;  2M67 A;  4WYV A;  4BJM A;  4IRE A;  1D1B A;  4HWI B;  4XBF B;  5FMN A;  3B5M A;  5ADX L;  1NEK A;  3I0Q A;  3U78 A;  2NTY A;  4ZI7 E;  1H7C A;  2DWG A;  2WB5 A;  1MMN A;  3A7M A;  2PG8 A;  1J1J A;  5FXZ A;  3UT5 E;  5CB4 E;  5HXE A;  2MAW A;  3QNU A;  3AVS A;  4AKI A;  4XAX B;  4HWF A;  4QH1 A;  4ILC A;  4X1I E;  5KX5 E;  2HPL A;  3VKG A;  3L39 A;  4KBM B;  5BR8 T;  5CFB A;  5HXH A;  2UUB T;  4QXB B;  1ZHC A;  5J2T E;  4LF5 T;  4B3R T;  2XAQ B;  2V6X A;  3RX6 A;  2WZH A;  3F57 A;  3WI3 A;  2L9Q A;  4LMK A;  3C51 A;  1BR0 A;  3KBU A;  4QKN A;  4DUY T;  4QXH B;  3AED A;  3AEG A;  4EV6 A;  2I59 A;  2XAS B;  1YW0 A;  2IW5 B;  2XAH B;  2LSY A;  2GK9 A;  2VVN A;  5L3C B;  1L0V A;  4TWH A;  2CHN A;  1OWA A;  4HFD A;  1UX4 A;  4P1N A;  5LMN T;  1MIY A;  2XUE A;  5EK3 A;  4KMC A;  3ZKR A;  5J0Z A;  1XNQ T;  1SHZ C;  3HKD E;  3RIU C;  2XAF B;  2C5K T;  3UFG A;  2X67 A;  2NR4 A;  3Q5X A;  2X51 A;  1M7K A;  2Q9Q D;  3PUX F;  1OED C;  3AVR A;  4A98 A;  2UUA T;  4IDO A;  2V6Y B;  4IST A;  2ZM6 T;  3ANW B;  2WZI A;  3KV9 A;  2DI4 A;  3FHN A;  4O2B E;  5IUX A;  2UXC T;  3OBV E;  4IE0 A;  4AIS A;  2KMF A;  4F8H A;  1HNZ T;  2WCA A;  2NW7 A;  2CXL A;  5FL1 A;  3CKD A;  1OED E;  2WU5 A;  3AE3 A;  5FY0 A;  4CN6 A;  2LOP A;  5HEH A;  2J1D G;  2MOZ A;  3L3P A;  3PTR B;  3J9X 1;  2CBJ A;  4UR9 A;  4BJN A;  4JI1 T;  2Q9Q A;  3ZT5 A;  2K9A A;  1XNR T;  4DV0 T;  4JI0 T;  3RKO A;  3HKC E;  1HCI A;  2ES0 A;  4JBW F;  3O1I A;  1WYC A;  4DV4 T;  3AAI A;  3RI5 A;  5F8P A;  3RC3 A;  4H63 V;  5JH7 E;  2V26 A;  3PUY F;  4A56 A;  2J4G A;  5JDG A;  2EHO B;  2LLY A;  3L8R A;  3MJX A;  2CCQ A;  4X62 T;  3CQX C;  1MIV A;  2XM1 A;  3FBL A;  5AQS B;  3LSV A;  3RC8 A;  1Y64 B;  3RHW A;  5ETW A;  3DP7 A;  4DR2 T;  1US7 B;  2NWB A;  4QWN B;  2BG9 B;  3KVA A;  2CEA A;  4IDN A;  4ILA A;  2NW9 A;  4HWC A;  2H88 A;  3AB3 B;  3JC6 D;  4IL4 A;  3N9Q A;  3JCF A;  3QK6 A;  3X1D A;  3AEE A;  2QRX A;  2X9H A;  3PU3 A;  4OX9 T;  1HTJ F;  3LFM A;  4UEL A;  4ZZC A;  2VVS A;  3CML A;  5HCJ A;  1MIW A;  5LJN A;  4CXY A;  3CPZ A;  2WU2 A;  5JDL A;  4NUU A;  1KNP A;  3D0T A;  2IUB A;  2KXP B;  4UXN B;  2V7I A;  3UU4 A;  4WBN E;  1YD8 G;  4G2A A;  3NVO A;  2W0G A;  2V5D A;  5HWX A;  4WZX A;  3FBZ A;  3KV4 A;  2W66 A;  1VCS A;  1N36 T;  3A5X A;  5AQM B;  3ONX A;  2DLR A;  2BS3 A;  2D2S A;  3GMI A;  4HWH A;  5AQV B;  3RQU A;  1KEY A;  4U31 A;  4ANJ A;  3CQG B;  4LF6 T;  4DV3 T;  3PDY A;  2X0Y A;  2W4X A;  2WWV A;  3NKZ A;  3H3A A;  4AKL A;  4KHZ F;  1KF6 A;  2E5V A;  5LB7 B;  3O1H A;  4EEB A;  4AQF A;  4P09 A;  2HN1 A;  4JV5 T;  2C0S A;  4EGW A;  3R84 B;  4LF4 T;  2E9X C;  4ZI2 D;  2WM9 A;  1LVF A;  4J2C A;  4IT4 A;  3GN5 A;  1XMQ T;  2ZM0 A;  3ZC0 A;  4E7Z A;  3N9L A;  4P0A A;  5FXW A;  5FL0 A;  1G8X A;  4YLH A;  4PK6 A;  3O4X E;  3E22 E;  2IIU A;  4CXW A;  4ZXL A;  5AQR B;  2LM2 A;  2XM2 A;  3K3O A;  5LP6 E;  2VAS A;  2YDS A;  3K3Q C;  5L4E A;  1IBM T;  1YKE B;  5LA6 E;  3ONJ A;  2VKO A;  3ZMV B;  4X1Y E;  3UUN A;  2BKP A;  3HA4 A;  2Z6E A;  3VRA A;  3C50 A;  4NXM T;  3UUX B;  3N9N A;  4KX6 A;  4U7I A;  3FZH B;  1DU2 A;  3S4U A;  4IE5 A;  5F3J A;  3QB5 K;  3N2O A;  4WBO A;  5JRC A;  3PE0 A;  4FJO A;  3E0Z A;  2EHO D;  4JYA T;  3AEC A;  3CIR A;  2D0T A;  4JI8 T;  4ZI3 D;  3N9M A;  2K5B B;  3ZT6 A;  2LRK A;  3ESL A;  3KV6 A;  5LJM A;  3C98 B;  3P4Q A;  4V1A v;  4AXP A;  5LBM A;  2BVM A;  3VR9 A;  4DR3 T;  3C4Z A;  3AE2 A;  2E5L T;  2V7L A;  2MPK A;  1VOM A;  4GK0 E;  1XDO A;  4DR7 T;  3AEA A;  2XQA A;  2ACZ A;  2JMH A;  4ILB A;  1LKX A;  1BR2 A;  1WYB A;  3P7I A;  4LF8 T;  3TLS A;  4EB6 E;  3UFE A;  3MK7 C;  3HL6 A;  4AQY T;  2I0M A;  4AKR B;  4DV1 T;  3I9Y A;  2PJQ A;  5HCM A;  3UTK A;  3CQC B;  4H9O C;  4IIJ E;  1MMA A;  4TZ4 C;  1SUM B;  3PUA A;  2VWA A;  4ZOL E;  4ZEY A;  2KZ7 B;  3V5S A;  3V5U A;  4IDQ A;  4EOZ B;  4LFB T;  1R8I A;  2UU9 T;  5FVL A;  5HEO A;  3HR0 A;  2FJD A;  3OYX A;  1HFA A;  1NAF A;  2MTQ A;  2MYS A;  1T8B A;  5AQH B;  4PNI A;  3E08 A;  2FJA A;  2N9D A;  4TNV A;  3AEB A;  3JAE A;  2QA7 A;  3RQW A;  3UQ7 A;  1D1C A;  1XZY A;  2LHN A;  4GK5 E;  2XY8 B;  2G0U A;  2VB6 A;  2KIN B;  4QX7 B;  1HG5 A;  3FXD B;  1XMO T;  2V7K A;  1BR1 A;  1BR4 A;  3T1Y T;  3ZMU B;  2VKJ A;  3SWH A;  1HX8 A;  4YTP A;  1I6Z A;  1KNR A;  5FVK A;  3CX6 B;  3CX7 B;  4CXX A;  2XSA A;  4UV9 B;  2DWK A;  4QXC B;  2CM0 A;  4EZ4 A;  3JC6 C;  4X66 T;  3TLT A;  3EDU A;  2W00 A;  4GKJ T;  4O4H E;  3ZST A;  5BMV E;  5AQN B;  4TV8 E;  4AKH A;  3RYF E;  5F5W A;  3ZCJ A;  2XQ8 A;  4OYJ A;  4Q25 A;  4CN1 A;  4UIG A;  3OTO T;  5ABE A;  3Q2M A;  2L8K A;  2CWO A;  3ZEF B;  4HEA A;  3GN5 B;  2WQY A;  2BZB A;  4YSY A;  2MBG A;  4EAH A;  2PBI A;  2YKS A;  2B1E A;  1FJG T;  2BKN A;  2IML A;  1W09 A;  1Y01 A;  3EAM A;  3ZSS A;  5CGM A;  4B3S T;  4JI7 T;  3AE6 A;  5LCY A;  3EUH A;  2XPK A;  5JDM A;  4CI3 B;  3N9P A;  3QOF A;  3LBX A;  4JI2 T;  3P4R A;  4QX8 B;  5ABG A;  2K24 A;  4CI2 B;  2A9U A;  3P8C D;  3K8P C;  2YOE A;  4YTM A;  2LSG A;  2ODV A;  3FB2 A;  2CLY B;  4DV5 T;  2IC9 A;  2RA1 A;  3SFD A;  5JRC B;  3B13 A;  5ABH A;  2OLT A;  3MKD A;  2W67 A;  4X64 T;  1QUU A;  4DV7 T;  4DV2 T;  4U72 A;  4I50 E;  4JI4 T;  2YN6 A;  4X5T A;  4NXN T;  2CE7 A;  3ETU A;  2D9D A;  3PUW F;  3J7Y q;  4ZI2 C;  2C5J A;  4UF0 A;  2KND A;  4G63 A;  5KDM C;  1XWM A;  3ZN1 B;  4JI6 T;  4TWF A;  3T1H T;  2ZM8 A;  3TLU A;  4BAY B;  5AFU L;  3FZM B;  4DMV A;  2VQF T;  2WDQ A;  4ISS A;  4KUM B;  4Z8X A;  2HPJ A;  2XAJ B;  4HKA A;  3P4W A;  3RRW A;  2BS4 A;  1VRB A;  3EVY A;  3TKL B;  4GKK T;  1HG2 A;  5JR9 A;  3VR8 A;  5E0O A;  2Y48 B;  3ZC1 A;  1WR0 A;  1UCU A;  3ZLI A;  3AE5 A;  2V7M A;  5LMU T;  2EHO C;  4PK5 A;  5KXJ A;  4IE6 A;  1KNZ A;  5L3B B;  4LML A;  4H9S E;  4HFC A;  1ZOY A;  1FEW A;  1WFD A;  4CN4 A;  3UUM A;  5M4Y A;  2DHR A;  3AA6 B;  3RPU A;  4PW8 A;  2BG9 C;  2JQH A;  5L47 A;  1U4Q A;  5EK4 A;  5LG3 A;  4JEU B;  4EZH A;  2BS2 A;  2LT3 A;  2VKD A;  5HYA A;  5H6R B;  2W63 A;  2OA5 A;  4H9Q C;  1ZKE A;  4TN7 B;  2WS3 A;  2BDE A;  3I9W A;  2PFV A;  2W2U A;  2BG9 E;  3AE1 A;  5JTG A;  3AAA B;  2CRB A;  4COF A;  4B6X A;  2V1D B;  2LEH A;  4MHC A;  2YDQ A;  4AQG A;  2BKO A;  2ODU A;  5HWY A;  1AJ3 A;  3JAF A;  3Q5W A;  4I43 B;  4BA9 A;  3FZF B;  1Z8U A;  1UUR A;  4YHH T;  2VQE T;  3UU3 A;  4TNW A;  3RYI E;  3W15 B;  4CZZ B;  3WAJ A;  4ASK A;  4IHJ E;  3N2K E;  3DJB A;  3OPC A;  3O9X A;  3EI0 A;  1HS7 A;  2LSK A;  2JMK A;  1FIO A;  3HI2 A;  3TLV A;  2BBH A;  4DV6 T;  2FUP A;  4A97 A;  3ZPO A;  4U74 A;  5EZY E;  5AQQ B;  2VK9 A;  4I0U A;  4M1P A;  4PAG A;  5AQT B;  2B76 A;  3RIU A;  2X0L B;  3C4X A;  3MA9 A;  2I6H A;  2WDR A;  4YSX A;  4O2A E;  3UU8 A;  3ZJ1 A;  5FXV A;  4DR5 T;  1V9D A;  3LBX B;  4Z91 A;  2XZE A;  4Z90 A;  4OFZ A;  3LK4 2;  1W0A A;  1OED A;  2JQ9 A;  3PJA A;  3F2E A;  3H3M A;  2OV9 A;  5DQW A;  4QHO A;  1D1A A;  3GA8 A;  3AAE B;  4O4J E;  1WR6 A;  4LFC T;  5ABF A;  4HFH A;  3R6N A;  3ZYK A;  2LSI A;  3LK3 B;  2YEV C;  5HXR A;  4HTE A;  2HH7 A;  4UVC B;  1D0Z A;  1U5P A;  3K3N A;  2FBW A;  4B3M T;  3CWZ B;  3M3Z B;  4H9R C;  2XQ9 A;  5HXS A;  2NP9 A;  4MFR A;  3PUZ F;  5LHG B;  5HAX A;  5AQF B;  2DCF A;  4DBR A;  4B3T T;  2WY2 A;  4HFE A;  4UF0 B;  3NZP A;  4DID B;  2YU1 A;  1WRD A;  5AQJ B;  5GON E;  5JDF A;  1VCT A;  3UUL A;  2LM9 A;  1JNR A;  3HKB E;  3SFE A;  5H6Q B;  1I94 T;  1IBK T;  4OK0 A;  4YHJ A;  4GOU A;  3AA1 B;  2LKH A;  2JQQ A;  2Q9Q C;  5AQK B;  4HGA A;  1HF8 A;  1GQE A;  1B7T A;  1E1H B;  1J5E T;  2NOX A;  2K48 A;  5JR9 B;  2FJB A;  2AE9 A;  3HKE E;  3N5L A;  3ABV A;  3NBX X;  3Q5E A;  5LBQ B;  5FYM A;  3F31 A;  4HN9 A;  4ZS3 A;  1YQ4 A;  2J62 A;  5LHI B;  2A3D A;  4NUV A;  5AQL B;  3PUR A;  5HEJ A;  5C3J A;  1MNE A;  4U33 A;  5AQP B;  2NTX A;  3H37 A;  5EK2 A;  3AA0 B;  1FMV A;  1UX5 A;  4CQI A;  4XZC A;  2E2A A;  5LOV E;  3MZK B;  5FY1 A;  2V5C A;  1IJ5 A;  2CMR A;  2JQK A;  4JUY A;  3IBP A;  4UV8 B;  1HX1 B;  1QLB A;  2LHR A;  5AQO B;  1J5W A;  5C2T A;  3SRZ A;  2H89 A;  4ZZB A;  1NWM X;  5IYZ E;  4LF9 T;  2XJ7 A;  2RPA A;  3JAD A;  1HR0 T;  1SA0 E;  5L3G B;  4LMJ A;  3IHR A;  3LJC A;  3BQL A;  4PK4 A;  4DVD A;  2UXB T;  2E9X D;  3AE9 A;  2IDO B;  3G06 A;  2XAG B;  4KHP T;  1X79 A;  4EXT A;  5FNV E;  4HFI A;  4IDP A;  1N34 T;  2AXD S;  4L5G A;  2C5I T;  3NRX A;  3KV5 A;  3BQK A;  4H9N C;  3B57 A;  5LNK A;  2XQ7 A;  3RLF F;  3ZN0 B;  5HEU A;  3ZMS B;  4PJL A;  3ZT7 A;  5L2L A;  3CX8 B;  3M65 A;  4TUY E;  2UXD T;  1W9R A;  3PV0 F;  1QSD A;  3WAK A;  3I1A A;  3N9O A;  4X20 E;  2YK0 A;  2E9X A;  1YXR A;  2NW8 A;  4HFV A;  3BK9 A;  3PUQ A;  4IGU A;  4OHF A;  4IE7 A;  1FMW A;  3AA7 B;  1N32 T;  4L9I A;  4JI3 T;  1OED B;  4EIW A;  3OKQ A;  3C4W A;  4OYK A;  4AQF C;  2H7O A;  2VUR A;  5CJ5 A;  3SS1 A;  3RRC A;  2DNX A;  2SPC A;  4U3C A;  5FP3 A;  5ABF B;  4K0K T;  5LYJ E;  3I0O A;  4DR1 T;  2D0U A;  5A1L A;  2HN2 A;  3AXJ A;  3VU7 H;  2M6I A;  1X9B A;  2WDV A;  2CXF A;  3U3I A;  3QB5 A;  4ILU A;  2CWY A;  5JVD E;  2QYW A;  4TV9 E;  4MLK A;  4PFP A;  4MAL A;  2WMO A;  3C64 A;  3AEF A;  4PFO A;  2LSJ A;  2QGS A;  3RH3 A;  3MXZ A;  2JJ9 A;  3P50 A;  3LDQ B;  1ZEE A;  4IDZ A;  2V7J A;  5CA1 E;  3LK2 B;  5L3D B;  3GWH A;  4YTN A;  4AKG A;  2H7V C;  3PJA J;  3NZQ A;  1JNZ A;  3AE8 A;  4TWD A;  2XQY A;  3FZK B;  4LF7 T;  5LGU B;  2CLY C;  2UXN B;  3IEE A;  1M62 A;  5LGT B;  3LG7 A;  2E8I A;  2XTL A;  4H9P C;  2YU2 A;  3ZJ2 A;  3EDV A;  2X0H A;  4TX5 A;  3UQ4 A;  2W61 A;  4LFA T;  2CA5 A;  4NPP A;  4O8S A;  5LG4 A;  4QH4 A;  4HFB A;  4IE4 A;  2WMN A;  1CHU A;  4YT0 A;  2WP9 A;  1IJ6 A;  2CBI A;  4WNK A;  5FKY A;  4PJN A;  4DUZ T;  2FJE A;  5LXT E;  3RIF A;  5AQG B;  5JDQ A;  4JI5 T;  1IBL T;  2X9X A;  4U7Y A;  2V8S V;  5C8Y E;  2BBJ A;  4JLE A;  4DR6 T;  4N78 D;  1UGO A;  4PJJ A;  1E2A A;  3PUV F;  5TAO A;  2KT9 A;  4YSZ A;  2J47 A;  3UUB A;  4ZI3 C;  3A8Y C;  2M6B A;  1N33 T;  5AQU B;  3CK6 A;  2XQ6 A;  5L3F B;  2LOS A;  1T7S A;  5JQG E;  4KI0 F;  3IF8 B;  4K0U A;  4HE8 A;  3ZYM A;  2LKG A;  3TLW A;  4KP3 C;  2A72 A;  5JRE A;  3EAB A;  5LHH B;  2WBL A;  5HXC A;  4YFS A;  4ZS2 A;  5L4H A;  5DAB A;  2KWH A;  3KVB A;  3ONL C;  4YJ2 E;  4C91 A;  1YQ3 A;  2VL8 A;  2P9B A;  4DO0 A;  4QH5 A;  2JPF A;  1W0B A;  2DL1 A;  5CA0 E;  2X9W A;  4YY3 T;  5DQV A;  3VRB A;  1ZV4 X;  5J1G A;  2H3R A;  3P4P A;  2YIN A;  4DMW A;  4I4T E;  4NIQ A;  4F6R C;  4UEM A;  2F4V T;  4AIU A;  4HWD A;  2IAK A;  1MMG A;  2IHR 1;  1OXZ A;  4FI5 A;  3KBT A;  3MAC A;  2D5U A;  4DBQ A;  4PJM A;  1EZ3 A;  3IA3 A;  2KWI B;  1HNW T;  4H63 H;  5IWA T;  4A5X A;  1UUS A;  3EHZ A;  2ACX A;  4IL9 A;  3ZMZ B;  3K1S A;  4ERR A;  1ZP0 A;  3PU8 A;  3FZL B;  4E7S A;  4GYS A;  4X65 T;  2IC6 A;  5FY7 A;  3QC9 A;  2E9X B;  2HHH T;  4GYR A;  1NEN A;  4UVB B;  3AE7 A;  3ZMT B;  3AE4 A;  4GIW A;  1MMD A;  2N1G A;  4MBQ A;  3ETV A;  4U2Z A;  5HEG A;  3OYZ A;  3BQI A;  1CUN A;  1D0Y A;  3FXE B;  2ZMA A;  2QVA A;  1KK7 A;  1E7P A;  2N2N A;  3PUG A;  3QUJ A;  5DJQ C;  3AXJ B;  5L3E B;  4EYY R;  2KSR A;  1WLX A;  4L0R A;  2X66 A;  3KIN B;  1XDP A;  4ADZ A;  2LJL A;  4UVA B;  2ZLY A;  4I55 E;  2CHO A;  2CXD A;  4P0B A;  2XSB A;  1YKH B;  1HNX T;  4YXD A;  2UUC T;  2L3L A;  2XQ5 A;  3OJA A;  1T98 A;  3Q9D A;  4DR4 T;  2K3W A;  2V6Y A;  3ANW A;  1IAP A;  2RP4 A;  5J2U E;  1D0X A;  3P4S A;  3PUS A;  1S94 A; 
#chains in the Genus database with same CATH homology
 3K1S A;  2JQ9 A;  4U7I A;  1WR0 A;  4CN6 A;  3ZST A;  4ZEY A;  4U2Z A;  2CPT A;  2W2U A;  3ZT6 A;  3ZSS A;  5FVK A;  5CGM A;  2LRL A;  2LRK A;  2WWV A;  2DL1 A;  4IT4 A;  4WZX A;  2JQH A;  3ZT5 A;  4CN4 A;  5CJ5 A;  4P1N A;  4U3C A;  1YXR A;  3EAB A;  5LB7 B;  2JQK A;  1WCR A;  2K3W A;  2V6Y A;  2CRB A;  2V6X A;  4U2Y A;  3ZT7 A;  4NIQ A;  2V6Y B;  4U33 A;  4U31 A;  4A5X A;  2WY2 A;  2MPK A;  2RPA A;  2XZE A;  5FVL A;  4CN1 A;  4U7Y A;  1WFD A;  2A9U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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