5AQIB

Fragment-based screening of hsp70 sheds light on the functional role of atp-binding site residues
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
112
structure length
112
Chain Sequence
SNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
pubmed doi rcsb
molecule tags Chaperone
source organism Homo sapiens
molecule keywords HEAT SHOCK COGNATE 71 KDA PROTEIN
total genus 45
structure length 112
sequence length 112
chains with identical sequence D
ec nomenclature
pdb deposition date 2015-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02179 BAG BAG domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.58.120 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase; Chain G, domain 1 BAG domain 5aqiB00
4HWFA 4HWIB 5AQHB 3FZHB 3M3ZB 4HWDA 5AQNB 3FZLB 5AQMB 5AQPB 5AQKB 5AQTB 3FZFB 5AQUB 5AQSB 3FZMB 1UGOA 5AQFB 4HWHA 5AQJB 1M7KA 1I6ZA 5AQQB 1T7SA 3FZKB 5AQOB 1HX1B 2D9DA 3A8YC 4HWCA 5AQRB 3LDQB 5AQGB 5AQVB 5AQLB 5AQIB 1M62A 1UK5A
chains in the Genus database with same CATH superfamily
2WMOA 4HN9A 4YHJA 1KNZA 4EB6E 3VKGA 5AQSB 2X9YA 2IUBA 1YW0A 2V5DA 1IAPA 5LHIB 3HKCE 4YTMA 1Z8UA 2PG8A 2LOPA 1E2AA 3UFGA 4EAHA 4IL4A 5ABGA 4LF8T 4ZI3D 2NW8A 4OK0A 3IHRA 5EK2A 4AI6A 5HXRA 2JRKA 3PV0F 5CB4E 4AIUA 3IF8B 3AEFA 2Q9QC 4AQFA 2XQYA 3OPCA 2EHOA 4F8HA 1YQ3A 5EK3A 1UGOA 2WDVA 2Q9QA 4O4LE 4P0BA 2XPKA 3R6NA 3Q5EA 2YINA 4AKIA 2IC9A 5JDLA 3I9WA 3CQGB 2A2FX 2BG9B 2IC6A 2WB5A 2V1DB 3HA4A 1ZKEA 2IAKA 2XQ5A 2JMKA 5IWAT 5FXZA 3ZC1A 4H9SE 4JBWF 3O1IA 5LB7B 4DUZT 5AFUL 1LVKA 3AEBA 3MKDA 2A9UA 2IDOB 2C0SA 3AXJA 2CRBA 2X9XA 4PK4A 2IMLA 2XQ9A 4UXNB 2IIUA 2X68A 1HNWT 1IZNB 1YXRA 3C64A 1ZV4X 4FJOA 3C98B 2CWYA 4CI1B 5J2TE 4I50E 1HNXT 3CKDA 5JDNA 4IE4A 3BQIA 3NZQA 1R8IA 4WZXA 3CQXC 4WBOA 2W4XA 4DBRA 3M3ZB 3CX7B 3AVSA 5DABA 3VKHA 5LHHB 2KZ7B 4J2CA 2E2AA 3JADA 1FMVA 4ZI3C 3EDUA 4ILUA 3RYHE 2WY2A 4QHOA 2YDQA 5AQKB 3K3QC 2BKOA 2MBGA 4ISTA 4EYUA 2XAQB 2D0TA 3BQLA 3PUSA 2BS3A 4BA9A 3UU6A 1XZYA 3UQ7A 2VB6A 4V1Av 2YDSA 3QB5K 3IEEA 3ZKRA 1NWMX 1BR2A 2ZM2A 1HTJF 3FZFB 4ZHQE 4AKLA 4QWNB 3R84B 4MLKA 1HNZT 5LBQB 2N1GA 2BG9C 5FXVA 4LF4T 5TAOA 5HXCA 2FJEA 4DBQA 4L5GA 3SWHA 1W09A 2BG9A 2H7VC 3VR9A 3ESLA 3EDVA 5HCMA 1N33T 3KBTA 3VRAA 1HX8A 4ZEYA 3O9XA 4DV6T 3AVRA 2WU2A 4YFSA 5ADXL 2LKGA 1W0BA 2G0UA 3FB2A 1LRZA 5FXXA 5L3GB 1OEDE 4UF0A 1MMDA 3AE4A 3KFWX 4B3TT 4DV0T 1FJGT 2VURA 2X0HA 3TLWA 1SHZC 5FL1A 4DR1T 5HXEA 5LGTB 1S35A 2YKSA 4G2AA 2D2SA 3P8CD 2OV9A 4GK0E 4QX8B 3KV5A 4M1PA 4IE7A 3RC8A 3FZHB 5ABFB 3H3AA 1CHUA 1VOMA 3FXDB 2KWIB 5C3JA 2DHRA 4QH1A 3ETVA 2WZHA 3AE7A 3TLVA 3RHWA 3E22E 4HWDA 2HPJA 5FVKA 3UU4A 1O3XA 2CMRA 3HKEE 4NIQA 1I6ZA 3EAMA 2UXNB 4TV9E 3OJAA 4QXBB 2NWBA 3ZCIA 3ANWB 4HWFA 4PK6A 4EIWA 2YOEA 4IE6A 4X1IE 3PJAA 2WCAA 2V5CA 3P4PA 1MIYA 5L4EA 5BMVE 2K3WA 2VL8A 2LT3A 2UXCT 3KV6A 2VASA 5FL0A 2VVNA 4ISSA 4CN1A 5IUXA 4YTPA 4ZZBA 2ZM6T 4CI2B 2ES0A 3E0ZA 4I43B 3RQWA 4EZHA 2E9XD 4ZI2D 2B1EA 4AQGA 4IDPA 3RH3A 4KP3C 1ZEEA 4NXNT 2ACZA 2LSKA 4WNKA 3P4RA 4EEDA 3PUVF 4JI8T 3CX8B 2PTFA 4YLHA 1MMNA 1HCIA 4LMJA 2XQ4A 3J9X1 4DMVA 5AQGB 3SS1A 2C5KT 3WAKA 4ADZA 4FI5A 4ZS3A 3A7MA 2W66A 1XDOA 4K0UA 3B5MA 4KHPT 3N9PA 1D1BA 3H3MA 4B6XA 5ETWA 5L3BB 4AQYT 3UU8A 3ZT7A 1US7B 3AE8A 2NTYA 5ABFA 5LP6E 1IBKT 4CZZB 1BR0A 3U3IA 4IDOA 3P4WA 4PJLA 4EZ4A 1BR1A 4C91A 5LNKA 1NAFA 2XZEA 1T98A 5L3EB 1XMOT 1QSDA 2EHOD 4EGWA 2X9HA 5DQVA 5JR9C 4H9QC 5JQGE 3ZMVB 3I0OA 2NP9A 1UCUA 2QYWA 3AE9A 3LG7A 3P7IA 2SPCA 3CQCB 4O4HE 3ANWA 5JDHA 5LMUT 1B7TA 3PURA 4HKAA 3RYFE 3EHZA 2V6YB 4G63A 2XQ6A 4U33A 3UT5E 2N9DA 3G06A 4U7IA 2AXDS 4PJNA 5M4YA 1MMGA 3JC6C 4F6RC 5LOVE 4ZOLE 3VRBA 1JNRA 2M6IA 1HR0T 2BBJA 3QNUA 3F31A 5JDGA 2CEAA 3AEDA 3N2KE 5HXHA 5HEUA 2VL0A 3TLUA 3HKDE 4B3ST 5KXJA 4YSYA 3QOFA 5LMNT 3NBXX 4TV8E 1NEKA 2KSRA 4GYRA 1QUUA 2JQHA 1HS7A 2V7LA 2W2UA 3FBLA 4I0UA 4U72A 5IYZE 2JMHA 3UU3A 5DQWA 4JLEA 4DR2T 3ZMTB 2UUAT 4DIDB 3K1SA 2LEHA 1XNQT 3ZEFB 2VK9A 3GA8A 3OYZA 2KWHA 5CFBA 3MZKB 1H7CA 1LVFA 2LLYA 2V6XA 3ZLIA 3WAJA 1XDPA 4DV5T 1WR0A 4QXCB 2UU9T 4Z8XA 2WZIA 2YN6A 3QUJA 3I0QA 1ZOYA 4DUYT 2OA5A 3DP7A 2LJLA 2LSGA 3K3NA 2DNXA 2KNDA 2A72A 3LBXB 4ZXLA 2Y8DA 3RKGA 3ZN0B 2QRXA 4CN4A 1YKEB 2LHRA 4KX6A 4WBNE 2RPAA 2IW5B 5EZYE 1L0VA 4NUUA 1CUNA 3L3PA 3AE5A 3CIRA 3OVUA 4X66T 1T8BA 4ILAA 4OYJA 4YXDA 1FIOA 3AEGA 4I55E 4AXPA 2K5BB 5A1LA 2W61A 3OKQA 4ZS2A 3E08A 3IBPA 4EV6A 1S94A 4JI5T 4UVBB 4CXWA 4N78D 3PU8A 4LMLA 2CA5A 4MFRA 1LKXA 1YD8G 1SE7A 4ILCA 4JYAT 3RLFF 4X20E 3LDQB 4GK5E 1Z0PA 5FY1A 2KT9A 5LHGB 2W0GA 4GYSA 4L0RA 4U3CA 3ZPOA 2XM2A 2K24A 5LXTE 3M65A 2KINB 4H9NC 3AA0B 2ZMAA 5AQVB 4WW0A 2LM9A 1UX5A 4LF7T 3UTKA 4JI3T 1ZP0A 4IDNA 3DTOA 1V9DA 1KNPA 3T1HT 2YEVC 4YY3T 2E8IA 1N36T 3AA7B 5CA1E 3QK6A 2XSBA 1T7SA 2M6BA 4JI4T 4UV8B 1KFYA 1Y64B 5AQMB 3UQ4A 4NPPA 2ZLYA 2R6GF 3PU3A 1M7KA 3LBXA 3KINB 2BDEA 4IT4A 3AE1A 4A98A 4IE5A 3GN5B 2BS4A 1FMWA 2FJDA 2XAGB 3PUGA 1GQEA 4CN6A 3CPZA 5F5WA 5LCYA 1NENA 4U31A 2N2NA 2E5LT 2XQAA 2QGSA 3UUNA 2LKHA 3N2OA 4DNDA 2C5IT 4DR5T 4YJ2E 1UUSA 3LJCA 1XMQT 4ZZCA 5FYMA 4DR7T 3NRXA 1D0XA 2UXBT 2XASB 4KUMB 2J4GA 5H6QB 4PNIA 3AA1B 3SOLA 2WS3A 3C51A 3FZKB 3WI3A 4I4TE 3UUBA 1T72A 4X5TA 2J1DG 2VVSA 4DR6T 3MACA 2WMNA 4NXMT 1I94T 2PJQA 3RRWA 3ZCJA 1YQ4A 4UVCB 5BR8T 3B13A 4TZ4C 1KEYA 2AE9A 2MPKA 2V7MA 3MXZA 5DJQC 4LF9T 3ZN1B 4YJ3E 2J62A 4IDZA 2I0MA 4X65T 2V8SV 4H9OC 4ZI7E 3RYIE 2JQQA 4O2BE 3RIAA 2CXFA 4BJMA 4JEUB 3LK3B 1HG2A 5HWXA 5HEHA 2XM1A 3LK42 3UFEA 4DVDA 2DCFA 3KBUA 5HCJA 1KF6A 3EVYA 3VU7H 5JR9B 1E1HB 3OBVE 3ONJA 3ZJ2A 2VKOA 3ZC0A 1D0ZA 1FEWA 2NW7A 5JH7E 2UUBT 1QLBA 3F57A 4HWIB 4JV5T 4BJNA 2BKPA 2E9XB 2FBWA 3RYCE 5HAXA 1YKHB 5FP3A 3N9LA 4DR4T 3GN5A 5ABEA 1M62A 3ABVA 3HR0A 5JDQA 4XBFB 2VKHA 2JQKA 2V7JA 4TWFA 3L8RA 2W62A 5JREA 2X9WA 2DWGA 3RQUA 1DU2A 2VKJA 3JAFA 2LSIA 4PFPA 3DJBA 2BG9E 2Y48B 4IIJE 2L3LA 2CCQA 2HN2A 2XAHB 3JAEA 3PE0A 3KVAA 1VCTA 4COFA 2D9DA 3N9MA 3UUMA 4DO0A 2H7OA 2ODVA 1UX4A 4OFZA 1UURA 2JQ9A 1KK7A 5LJNA 3OYXA 3RKOA 3FHNA 2XJ7A 1OXZA 4U7YA 4E7SA 2FJAA 3O4XE 1KNRA 1HX1B 2XQ3A 4UELA 3KVBA 3PUYF 3EABA 2BVMA 4DR3T 2EHOB 2YDRA 1Y01A 2ODUA 4GOUA 1J5ET 4PK5A 2Q9QD 4JI2T 4B3MT 4QKNA 2LSYA 2NTXA 2WDRA 4HFVA 1WR6A 4JEHB 2LM2A 3HKBE 5JR9A 3K3OA 4OYKA 1OEDB 5L4HA 3ZYMA 4LFCT 5IHYA 2DWKA 1W9RA 3PJAJ 1WFDA 4H63V 2I6HA 4MBQA 2XAJB 3C4ZA 2E9XC 4ZI2C 3J7Yq 5JDMA 4YHHT 3I9YA 3ZYLA 2ZM8A 1VCSA 5AQPB 1MMAA 2HN1A 3ETUA 3FZMB 2E9XA 4CQIA 2VQET 1N32T 2JIWA 4JUYA 3PUZF 4B3RT 5J2UE 4PAGA 3JCFA 2UXDT 2ACXA 3PDYA 1WCRA 3N2GE 3ZMUB 4HFDA 3W15B 3IA3A 2W67A 3FZLB 5AQUB 2CLYB 5AQFB 4QXHB 2KXPB 3RRCA 3A8YC 5HXSA 1D0YA 3TKLB 1IJ5A 2I59A 3UUXB 1G73A 2UUCT 2D5UA 3T8OA 2M67A 5C2TA 3AEAA 4IHJE 3RX6A 3N9QA 2L8KA 3H37A 4TNWA 5J0ZA 1ZHCA 2F4VT 3ZMSB 4OX9T 2K48A 3MK7C 5HYAA 3P50A 4AQFC 4K0KT 1MNEA 2DLRA 2W00A 2Z6EA 2EHOC 4H9RC 4LF5T 2LSJA 3N9NA 3RI5A 5HEGA 1U5PA 3A5XA 3PUAA 3PUQA 4LMKA 2HHHT 4YT0A 2ZM0A 4H63H 2FJBA 4EOZB 3RC3A 5C8YE 3MJXA 2X66A 4HFIA 3Q9DA 1EZ3A 5KDMC 2XQ7A 1OEDC 3LFMA 4ERRA 5AQLB 3CMLA 3O1JA 2WM9A 4KMCA 2WBLA 5CGMA 1W0AA 2V6YA 4XZCA 1OEDA 2KMFA 4U2YA 2WP9A 4P1NA 4LFBT 4DV7T 3S4UA 2PBIA 4P09A 5FVLA 5FY0A 3ZYKA 3TLSA 4GIWA 3ZT6A 5CA0E 1IJ6A 2RA1A 2QVAA 4QH5A 4PFOA 3QC9A 2E5VA 4UF0B 4CI3B 2L9QA 1HG5A 3EI0A 3NRYA 4EXTA 4JI7T 4A5XA 2UXXB 4HFBA 2JPFA 2OLTA 2CLYC 2C5JA 4HEAA 2WWUA 2BS2A 1MIWA 3GWHA 3Q5XA 4O8SA 5FNVE 3NKZA 2XQ8A 4X64T 5L3CB 3RGLA 1HFAA 5J1GA 4HWCA 4KBMB 2CWOA 3N9OA 3RIUC 4EYYR 4GKKT 1MNDA 2LRKA 4ILBA 4KI0F 4EEBA 5LGUB 2CBIA 4IGUA 1AJ3A 4AKRB 4TN7B 3RIUA 3X1DA 1IBMT 5JVDE 1MIVA 5AQRB 3ONXA 5F3JA 4AISA 2CE7A 3C50A 3EUHA 4A56A 4OHFA 2D0UA 4TNVA 2NOXA 2CHNA 3MA9A 4DV3T 1WYBA 3C4WA 2WDQA 2VQFT 2W63A 2A3DA 3CK6A 2MAWA 1N34T 1XWMA 2BZBA 3AAEB 4UR9A 5FXWA 3OTOT 2LHNA 4P0AA 1J5WA 2NR4A 3ZMZB 3ONLC 3FXEB 1WYCA 4AKHA 2IHR1 1IBLT 3AAIA 4TUYE 4UEMA 2BBHA 4PJJA 3C4XA 4TX5A 3RF1A 2PFVA 1X79A 2H89A 4JI0T 1WRDA 3AE3A 4NUVA 5KX5E 4LFAT 2BVLA 2VWAA 5AQHB 5AQNB 3P4SA 5HEJA 2VKDA 3GMIA 2P9BA 3K8PC 1J1JA 2YK0A 4YSXA 4AKGA 2X0YA 2XY8B 5GONE 5FY7A 3LSVA 4MHCA 4UVAB 2MTQA 2RP4A 3AAAB 1U4QA 5LG3A 2XUEA 2K9AA 4CXYA 4YTNA 5JRCB 1VRBA 2YU1A 3AE6A 4O4JE 4HE8A 4TWHA 5AQJB 4IL9A 2XHEB 2WWVA 3BK9A 1E7PA 3L39A 2Y6XA 3Q2MA 3V5UA 1D1AA 2V7IA 4HTEA 4E7ZA 1JNZA 3VHLA 2MYSA 3AEEA 4KHZF 2YU2A 5LYJE 2KLQA 3SRZA 2JJ9A 1SA0E 4U74A 3V5SA 4DMWA 3AECA 3KV4A 4A97A 4LF6T 4WYVA 1BR4A 3PUWF 1X9BA 2LOSA 3NZPA 3T1YT 2X67A 4PW8A 5LBMA 4ASKA 2H88A 3B57A 4HFCA 4XAXB 5EK4A 5FKYA 3HI2A 4QX7B 2HPLA 2LRLA 2CPTA 4GKJT 5AQOB 4O2AE 3JC6D 4HGAA 3NVOA 3AE2A 4PJMA 4MALA 3PUXF 3VR8A 3ZJ1A 2XSAA 3O1HA 5FMNA 3ZT5A 3AA6B 2QA7A 1D1CA 1XNRT 4TWDA 3AB3B 3RIFA 3ZSSA 2WSSV 4CXXA 4Z90A 4U2ZA 3FBZA 1WLXA 5L2LA 2XAFB 4L9IA 3CX6B 3D0TA 5F8PA 2WQYA 1SUMB 5L3DB 4IREA 3KDSE 2X0LB 4C90A 2LE8A 1HF8A 3L09A 4X1YE 4X1KE 4DV4T 5E0OA 2CBJA 3QB5A 1G8XA 2Q9QB 3CVRA 3BQKA 3KV9A 4UIGA 5JRCA 2B76A 2H3RA 2WAUA 3RPUA 1OWAA 4YSZA 4UV9B 4Q25A 2BKNA 3I1AA 2DL1A 3Q5DA 4HWHA 4H9PC 3CWZB 2CM0A 3LK2B 4ANJA 3HL6A 2WU5A 5ABHA 2FUPA 4HFEA 3UU5A 4JI6T 2MOZA 2NW9A 2V26A 3TLTA 3F2EA 5H6RB 2DI4A 3U78A 5HWYA 5LG4A 4IE0A 4X62T 3P4QA 5LA6E 5L47A 3AXJB 2GK9A 5JTGA 5AQQB 4HFHA 4DV1T 5L3FB 2HH7A 2CXLA 4BAYB 5LGNB 2CHOA 3SFDA 4JI1T 2X51A 3PTRB 5HEOA 5CJ5A 5JDFA 4IDQA 2V7KA 2CXDA 3ZSTA 5LJMA 3NWIA 5AQTB 3Q5WA 4O4IE 4Z91A 2J47A 3UULA 4DV2T 3N5LA 4QH4A 3SFEA 2XTLA 5AQIB 5KMGP 1UK5A
chains in the Genus database with same CATH topology
4HWFA 4HWIB 5AQHB 3FZHB 3M3ZB 4HWDA 5AQNB 3FZLB 5AQMB 5AQPB 5AQKB 5AQTB 3FZFB 5AQUB 5AQSB 3FZMB 1UGOA 5AQFB 4HWHA 5AQJB 1M7KA 1I6ZA 5AQQB 1T7SA 3FZKB 5AQOB 1HX1B 2D9DA 3A8YC 4HWCA 5AQRB 3LDQB 5AQGB 5AQVB 5AQLB 5AQIB 1M62A 1UK5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HWF A;  4HWI B;  5AQH B;  3FZH B;  3M3Z B;  4HWD A;  5AQN B;  3FZL B;  5AQM B;  5AQP B;  5AQK B;  5AQT B;  3FZF B;  5AQU B;  5AQS B;  3FZM B;  1UGO A;  5AQF B;  4HWH A;  5AQJ B;  1M7K A;  1I6Z A;  5AQQ B;  1T7S A;  3FZK B;  5AQO B;  1HX1 B;  2D9D A;  3A8Y C;  4HWC A;  5AQR B;  3LDQ B;  5AQG B;  5AQV B;  5AQL B;  5AQI B;  1M62 A;  1UK5 A; 
#chains in the Genus database with same CATH topology
 2WMO A;  4HN9 A;  4YHJ A;  1KNZ A;  4EB6 E;  3VKG A;  5AQS B;  2X9Y A;  2IUB A;  1YW0 A;  2V5D A;  1IAP A;  5LHI B;  3HKC E;  4YTM A;  1Z8U A;  2PG8 A;  2LOP A;  1E2A A;  3UFG A;  4EAH A;  4IL4 A;  5ABG A;  4LF8 T;  4ZI3 D;  2NW8 A;  4OK0 A;  3IHR A;  5EK2 A;  4AI6 A;  5HXR A;  2JRK A;  3PV0 F;  5CB4 E;  4AIU A;  3IF8 B;  3AEF A;  2Q9Q C;  4AQF A;  2XQY A;  3OPC A;  2EHO A;  4F8H A;  1YQ3 A;  5EK3 A;  1UGO A;  2WDV A;  2Q9Q A;  4O4L E;  4P0B A;  2XPK A;  3R6N A;  3Q5E A;  2YIN A;  4AKI A;  2IC9 A;  5JDL A;  3I9W A;  3CQG B;  2A2F X;  2BG9 B;  2IC6 A;  2WB5 A;  2V1D B;  3HA4 A;  1ZKE A;  2IAK A;  2XQ5 A;  2JMK A;  5IWA T;  5FXZ A;  3ZC1 A;  4H9S E;  4JBW F;  3O1I A;  5LB7 B;  4DUZ T;  5AFU L;  1LVK A;  3AEB A;  3MKD A;  2A9U A;  2IDO B;  2C0S A;  3AXJ A;  2CRB A;  2X9X A;  4PK4 A;  2IML A;  2XQ9 A;  4UXN B;  2IIU A;  2X68 A;  1HNW T;  1IZN B;  1YXR A;  3C64 A;  1ZV4 X;  4FJO A;  3C98 B;  2CWY A;  4CI1 B;  5J2T E;  4I50 E;  1HNX T;  3CKD A;  5JDN A;  4IE4 A;  3BQI A;  3NZQ A;  1R8I A;  4WZX A;  3CQX C;  4WBO A;  2W4X A;  4DBR A;  3M3Z B;  3CX7 B;  3AVS A;  5DAB A;  3VKH A;  5LHH B;  2KZ7 B;  4J2C A;  2E2A A;  3JAD A;  1FMV A;  4ZI3 C;  3EDU A;  4ILU A;  3RYH E;  2WY2 A;  4QHO A;  2YDQ A;  5AQK B;  3K3Q C;  2BKO A;  2MBG A;  4IST A;  4EYU A;  2XAQ B;  2D0T A;  3BQL A;  3PUS A;  2BS3 A;  4BA9 A;  3UU6 A;  1XZY A;  3UQ7 A;  2VB6 A;  4V1A v;  2YDS A;  3QB5 K;  3IEE A;  3ZKR A;  1NWM X;  1BR2 A;  2ZM2 A;  1HTJ F;  3FZF B;  4ZHQ E;  4AKL A;  4QWN B;  3R84 B;  4MLK A;  1HNZ T;  5LBQ B;  2N1G A;  2BG9 C;  5FXV A;  4LF4 T;  5TAO A;  5HXC A;  2FJE A;  4DBQ A;  4L5G A;  3SWH A;  1W09 A;  2BG9 A;  2H7V C;  3VR9 A;  3ESL A;  3EDV A;  5HCM A;  1N33 T;  3KBT A;  3VRA A;  1HX8 A;  4ZEY A;  3O9X A;  4DV6 T;  3AVR A;  2WU2 A;  4YFS A;  5ADX L;  2LKG A;  1W0B A;  2G0U A;  3FB2 A;  1LRZ A;  5FXX A;  5L3G B;  1OED E;  4UF0 A;  1MMD A;  3AE4 A;  3KFW X;  4B3T T;  4DV0 T;  1FJG T;  2VUR A;  2X0H A;  3TLW A;  1SHZ C;  5FL1 A;  4DR1 T;  5HXE A;  5LGT B;  1S35 A;  2YKS A;  4G2A A;  2D2S A;  3P8C D;  2OV9 A;  4GK0 E;  4QX8 B;  3KV5 A;  4M1P A;  4IE7 A;  3RC8 A;  3FZH B;  5ABF B;  3H3A A;  1CHU A;  1VOM A;  3FXD B;  2KWI B;  5C3J A;  2DHR A;  4QH1 A;  3ETV A;  2WZH A;  3AE7 A;  3TLV A;  3RHW A;  3E22 E;  4HWD A;  2HPJ A;  5FVK A;  3UU4 A;  1O3X A;  2CMR A;  3HKE E;  4NIQ A;  1I6Z A;  3EAM A;  2UXN B;  4TV9 E;  3OJA A;  4QXB B;  2NWB A;  3ZCI A;  3ANW B;  4HWF A;  4PK6 A;  4EIW A;  2YOE A;  4IE6 A;  4X1I E;  3PJA A;  2WCA A;  2V5C A;  3P4P A;  1MIY A;  5L4E A;  5BMV E;  2K3W A;  2VL8 A;  2LT3 A;  2UXC T;  3KV6 A;  2VAS A;  5FL0 A;  2VVN A;  4ISS A;  4CN1 A;  5IUX A;  4YTP A;  4ZZB A;  2ZM6 T;  4CI2 B;  2ES0 A;  3E0Z A;  4I43 B;  3RQW A;  4EZH A;  2E9X D;  4ZI2 D;  2B1E A;  4AQG A;  4IDP A;  3RH3 A;  4KP3 C;  1ZEE A;  4NXN T;  2ACZ A;  2LSK A;  4WNK A;  3P4R A;  4EED A;  3PUV F;  4JI8 T;  3CX8 B;  2PTF A;  4YLH A;  1MMN A;  1HCI A;  4LMJ A;  2XQ4 A;  3J9X 1;  4DMV A;  5AQG B;  3SS1 A;  2C5K T;  3WAK A;  4ADZ A;  4FI5 A;  4ZS3 A;  3A7M A;  2W66 A;  1XDO A;  4K0U A;  3B5M A;  4KHP T;  3N9P A;  1D1B A;  3H3M A;  4B6X A;  5ETW A;  5L3B B;  4AQY T;  3UU8 A;  3ZT7 A;  1US7 B;  3AE8 A;  2NTY A;  5ABF A;  5LP6 E;  1IBK T;  4CZZ B;  1BR0 A;  3U3I A;  4IDO A;  3P4W A;  4PJL A;  4EZ4 A;  1BR1 A;  4C91 A;  5LNK A;  1NAF A;  2XZE A;  1T98 A;  5L3E B;  1XMO T;  1QSD A;  2EHO D;  4EGW A;  2X9H A;  5DQV A;  5JR9 C;  4H9Q C;  5JQG E;  3ZMV B;  3I0O A;  2NP9 A;  1UCU A;  2QYW A;  3AE9 A;  3LG7 A;  3P7I A;  2SPC A;  3CQC B;  4O4H E;  3ANW A;  5JDH A;  5LMU T;  1B7T A;  3PUR A;  4HKA A;  3RYF E;  3EHZ A;  2V6Y B;  4G63 A;  2XQ6 A;  4U33 A;  3UT5 E;  2N9D A;  3G06 A;  4U7I A;  2AXD S;  4PJN A;  5M4Y A;  1MMG A;  3JC6 C;  4F6R C;  5LOV E;  4ZOL E;  3VRB A;  1JNR A;  2M6I A;  1HR0 T;  2BBJ A;  3QNU A;  3F31 A;  5JDG A;  2CEA A;  3AED A;  3N2K E;  5HXH A;  5HEU A;  2VL0 A;  3TLU A;  3HKD E;  4B3S T;  5KXJ A;  4YSY A;  3QOF A;  5LMN T;  3NBX X;  4TV8 E;  1NEK A;  2KSR A;  4GYR A;  1QUU A;  2JQH A;  1HS7 A;  2V7L A;  2W2U A;  3FBL A;  4I0U A;  4U72 A;  5IYZ E;  2JMH A;  3UU3 A;  5DQW A;  4JLE A;  4DR2 T;  3ZMT B;  2UUA T;  4DID B;  3K1S A;  2LEH A;  1XNQ T;  3ZEF B;  2VK9 A;  3GA8 A;  3OYZ A;  2KWH A;  5CFB A;  3MZK B;  1H7C A;  1LVF A;  2LLY A;  2V6X A;  3ZLI A;  3WAJ A;  1XDP A;  4DV5 T;  1WR0 A;  4QXC B;  2UU9 T;  4Z8X A;  2WZI A;  2YN6 A;  3QUJ A;  3I0Q A;  1ZOY A;  4DUY T;  2OA5 A;  3DP7 A;  2LJL A;  2LSG A;  3K3N A;  2DNX A;  2KND A;  2A72 A;  3LBX B;  4ZXL A;  2Y8D A;  3RKG A;  3ZN0 B;  2QRX A;  4CN4 A;  1YKE B;  2LHR A;  4KX6 A;  4WBN E;  2RPA A;  2IW5 B;  5EZY E;  1L0V A;  4NUU A;  1CUN A;  3L3P A;  3AE5 A;  3CIR A;  3OVU A;  4X66 T;  1T8B A;  4ILA A;  4OYJ A;  4YXD A;  1FIO A;  3AEG A;  4I55 E;  4AXP A;  2K5B B;  5A1L A;  2W61 A;  3OKQ A;  4ZS2 A;  3E08 A;  3IBP A;  4EV6 A;  1S94 A;  4JI5 T;  4UVB B;  4CXW A;  4N78 D;  3PU8 A;  4LML A;  2CA5 A;  4MFR A;  1LKX A;  1YD8 G;  1SE7 A;  4ILC A;  4JYA T;  3RLF F;  4X20 E;  3LDQ B;  4GK5 E;  1Z0P A;  5FY1 A;  2KT9 A;  5LHG B;  2W0G A;  4GYS A;  4L0R A;  4U3C A;  3ZPO A;  2XM2 A;  2K24 A;  5LXT E;  3M65 A;  2KIN B;  4H9N C;  3AA0 B;  2ZMA A;  5AQV B;  4WW0 A;  2LM9 A;  1UX5 A;  4LF7 T;  3UTK A;  4JI3 T;  1ZP0 A;  4IDN A;  3DTO A;  1V9D A;  1KNP A;  3T1H T;  2YEV C;  4YY3 T;  2E8I A;  1N36 T;  3AA7 B;  5CA1 E;  3QK6 A;  2XSB A;  1T7S A;  2M6B A;  4JI4 T;  4UV8 B;  1KFY A;  1Y64 B;  5AQM B;  3UQ4 A;  4NPP A;  2ZLY A;  2R6G F;  3PU3 A;  1M7K A;  3LBX A;  3KIN B;  2BDE A;  4IT4 A;  3AE1 A;  4A98 A;  4IE5 A;  3GN5 B;  2BS4 A;  1FMW A;  2FJD A;  2XAG B;  3PUG A;  1GQE A;  4CN6 A;  3CPZ A;  5F5W A;  5LCY A;  1NEN A;  4U31 A;  2N2N A;  2E5L T;  2XQA A;  2QGS A;  3UUN A;  2LKH A;  3N2O A;  4DND A;  2C5I T;  4DR5 T;  4YJ2 E;  1UUS A;  3LJC A;  1XMQ T;  4ZZC A;  5FYM A;  4DR7 T;  3NRX A;  1D0X A;  2UXB T;  2XAS B;  4KUM B;  2J4G A;  5H6Q B;  4PNI A;  3AA1 B;  3SOL A;  2WS3 A;  3C51 A;  3FZK B;  3WI3 A;  4I4T E;  3UUB A;  1T72 A;  4X5T A;  2J1D G;  2VVS A;  4DR6 T;  3MAC A;  2WMN A;  4NXM T;  1I94 T;  2PJQ A;  3RRW A;  3ZCJ A;  1YQ4 A;  4UVC B;  5BR8 T;  3B13 A;  4TZ4 C;  1KEY A;  2AE9 A;  2MPK A;  2V7M A;  3MXZ A;  5DJQ C;  4LF9 T;  3ZN1 B;  4YJ3 E;  2J62 A;  4IDZ A;  2I0M A;  4X65 T;  2V8S V;  4H9O C;  4ZI7 E;  3RYI E;  2JQQ A;  4O2B E;  3RIA A;  2CXF A;  4BJM A;  4JEU B;  3LK3 B;  1HG2 A;  5HWX A;  5HEH A;  2XM1 A;  3LK4 2;  3UFE A;  4DVD A;  2DCF A;  3KBU A;  5HCJ A;  1KF6 A;  3EVY A;  3VU7 H;  5JR9 B;  1E1H B;  3OBV E;  3ONJ A;  3ZJ2 A;  2VKO A;  3ZC0 A;  1D0Z A;  1FEW A;  2NW7 A;  5JH7 E;  2UUB T;  1QLB A;  3F57 A;  4HWI B;  4JV5 T;  4BJN A;  2BKP A;  2E9X B;  2FBW A;  3RYC E;  5HAX A;  1YKH B;  5FP3 A;  3N9L A;  4DR4 T;  3GN5 A;  5ABE A;  1M62 A;  3ABV A;  3HR0 A;  5JDQ A;  4XBF B;  2VKH A;  2JQK A;  2V7J A;  4TWF A;  3L8R A;  2W62 A;  5JRE A;  2X9W A;  2DWG A;  3RQU A;  1DU2 A;  2VKJ A;  3JAF A;  2LSI A;  4PFP A;  3DJB A;  2BG9 E;  2Y48 B;  4IIJ E;  2L3L A;  2CCQ A;  2HN2 A;  2XAH B;  3JAE A;  3PE0 A;  3KVA A;  1VCT A;  4COF A;  2D9D A;  3N9M A;  3UUM A;  4DO0 A;  2H7O A;  2ODV A;  1UX4 A;  4OFZ A;  1UUR A;  2JQ9 A;  1KK7 A;  5LJN A;  3OYX A;  3RKO A;  3FHN A;  2XJ7 A;  1OXZ A;  4U7Y A;  4E7S A;  2FJA A;  3O4X E;  1KNR A;  1HX1 B;  2XQ3 A;  4UEL A;  3KVB A;  3PUY F;  3EAB A;  2BVM A;  4DR3 T;  2EHO B;  2YDR A;  1Y01 A;  2ODU A;  4GOU A;  1J5E T;  4PK5 A;  2Q9Q D;  4JI2 T;  4B3M T;  4QKN A;  2LSY A;  2NTX A;  2WDR A;  4HFV A;  1WR6 A;  4JEH B;  2LM2 A;  3HKB E;  5JR9 A;  3K3O A;  4OYK A;  1OED B;  5L4H A;  3ZYM A;  4LFC T;  5IHY A;  2DWK A;  1W9R A;  3PJA J;  1WFD A;  4H63 V;  2I6H A;  4MBQ A;  2XAJ B;  3C4Z A;  2E9X C;  4ZI2 C;  3J7Y q;  5JDM A;  4YHH T;  3I9Y A;  3ZYL A;  2ZM8 A;  1VCS A;  5AQP B;  1MMA A;  2HN1 A;  3ETU A;  3FZM B;  2E9X A;  4CQI A;  2VQE T;  1N32 T;  2JIW A;  4JUY A;  3PUZ F;  4B3R T;  5J2U E;  4PAG A;  3JCF A;  2UXD T;  2ACX A;  3PDY A;  1WCR A;  3N2G E;  3ZMU B;  4HFD A;  3W15 B;  3IA3 A;  2W67 A;  3FZL B;  5AQU B;  2CLY B;  5AQF B;  4QXH B;  2KXP B;  3RRC A;  3A8Y C;  5HXS A;  1D0Y A;  3TKL B;  1IJ5 A;  2I59 A;  3UUX B;  1G73 A;  2UUC T;  2D5U A;  3T8O A;  2M67 A;  5C2T A;  3AEA A;  4IHJ E;  3RX6 A;  3N9Q A;  2L8K A;  3H37 A;  4TNW A;  5J0Z A;  1ZHC A;  2F4V T;  3ZMS B;  4OX9 T;  2K48 A;  3MK7 C;  5HYA A;  3P50 A;  4AQF C;  4K0K T;  1MNE A;  2DLR A;  2W00 A;  2Z6E A;  2EHO C;  4H9R C;  4LF5 T;  2LSJ A;  3N9N A;  3RI5 A;  5HEG A;  1U5P A;  3A5X A;  3PUA A;  3PUQ A;  4LMK A;  2HHH T;  4YT0 A;  2ZM0 A;  4H63 H;  2FJB A;  4EOZ B;  3RC3 A;  5C8Y E;  3MJX A;  2X66 A;  4HFI A;  3Q9D A;  1EZ3 A;  5KDM C;  2XQ7 A;  1OED C;  3LFM A;  4ERR A;  5AQL B;  3CML A;  3O1J A;  2WM9 A;  4KMC A;  2WBL A;  5CGM A;  1W0A A;  2V6Y A;  4XZC A;  1OED A;  2KMF A;  4U2Y A;  2WP9 A;  4P1N A;  4LFB T;  4DV7 T;  3S4U A;  2PBI A;  4P09 A;  5FVL A;  5FY0 A;  3ZYK A;  3TLS A;  4GIW A;  3ZT6 A;  5CA0 E;  1IJ6 A;  2RA1 A;  2QVA A;  4QH5 A;  4PFO A;  3QC9 A;  2E5V A;  4UF0 B;  4CI3 B;  2L9Q A;  1HG5 A;  3EI0 A;  3NRY A;  4EXT A;  4JI7 T;  4A5X A;  2UXX B;  4HFB A;  2JPF A;  2OLT A;  2CLY C;  2C5J A;  4HEA A;  2WWU A;  2BS2 A;  1MIW A;  3GWH A;  3Q5X A;  4O8S A;  5FNV E;  3NKZ A;  2XQ8 A;  4X64 T;  5L3C B;  3RGL A;  1HFA A;  5J1G A;  4HWC A;  4KBM B;  2CWO A;  3N9O A;  3RIU C;  4EYY R;  4GKK T;  1MND A;  2LRK A;  4ILB A;  4KI0 F;  4EEB A;  5LGU B;  2CBI A;  4IGU A;  1AJ3 A;  4AKR B;  4TN7 B;  3RIU A;  3X1D A;  1IBM T;  5JVD E;  1MIV A;  5AQR B;  3ONX A;  5F3J A;  4AIS A;  2CE7 A;  3C50 A;  3EUH A;  4A56 A;  4OHF A;  2D0U A;  4TNV A;  2NOX A;  2CHN A;  3MA9 A;  4DV3 T;  1WYB A;  3C4W A;  2WDQ A;  2VQF T;  2W63 A;  2A3D A;  3CK6 A;  2MAW A;  1N34 T;  1XWM A;  2BZB A;  3AAE B;  4UR9 A;  5FXW A;  3OTO T;  2LHN A;  4P0A A;  1J5W A;  2NR4 A;  3ZMZ B;  3ONL C;  3FXE B;  1WYC A;  4AKH A;  2IHR 1;  1IBL T;  3AAI A;  4TUY E;  4UEM A;  2BBH A;  4PJJ A;  3C4X A;  4TX5 A;  3RF1 A;  2PFV A;  1X79 A;  2H89 A;  4JI0 T;  1WRD A;  3AE3 A;  4NUV A;  5KX5 E;  4LFA T;  2BVL A;  2VWA A;  5AQH B;  5AQN B;  3P4S A;  5HEJ A;  2VKD A;  3GMI A;  2P9B A;  3K8P C;  1J1J A;  2YK0 A;  4YSX A;  4AKG A;  2X0Y A;  2XY8 B;  5GON E;  5FY7 A;  3LSV A;  4MHC A;  4UVA B;  2MTQ A;  2RP4 A;  3AAA B;  1U4Q A;  5LG3 A;  2XUE A;  2K9A A;  4CXY A;  4YTN A;  5JRC B;  1VRB A;  2YU1 A;  3AE6 A;  4O4J E;  4HE8 A;  4TWH A;  5AQJ B;  4IL9 A;  2XHE B;  2WWV A;  3BK9 A;  1E7P A;  3L39 A;  2Y6X A;  3Q2M A;  3V5U A;  1D1A A;  2V7I A;  4HTE A;  4E7Z A;  1JNZ A;  3VHL A;  2MYS A;  3AEE A;  4KHZ F;  2YU2 A;  5LYJ E;  2KLQ A;  3SRZ A;  2JJ9 A;  1SA0 E;  4U74 A;  3V5S A;  4DMW A;  3AEC A;  3KV4 A;  4A97 A;  4LF6 T;  4WYV A;  1BR4 A;  3PUW F;  1X9B A;  2LOS A;  3NZP A;  3T1Y T;  2X67 A;  4PW8 A;  5LBM A;  4ASK A;  2H88 A;  3B57 A;  4HFC A;  4XAX B;  5EK4 A;  5FKY A;  3HI2 A;  4QX7 B;  2HPL A;  2LRL A;  2CPT A;  4GKJ T;  5AQO B;  4O2A E;  3JC6 D;  4HGA A;  3NVO A;  3AE2 A;  4PJM A;  4MAL A;  3PUX F;  3VR8 A;  3ZJ1 A;  2XSA A;  3O1H A;  5FMN A;  3ZT5 A;  3AA6 B;  2QA7 A;  1D1C A;  1XNR T;  4TWD A;  3AB3 B;  3RIF A;  3ZSS A;  2WSS V;  4CXX A;  4Z90 A;  4U2Z A;  3FBZ A;  1WLX A;  5L2L A;  2XAF B;  4L9I A;  3CX6 B;  3D0T A;  5F8P A;  2WQY A;  1SUM B;  5L3D B;  4IRE A;  3KDS E;  2X0L B;  4C90 A;  2LE8 A;  1HF8 A;  3L09 A;  4X1Y E;  4X1K E;  4DV4 T;  5E0O A;  2CBJ A;  3QB5 A;  1G8X A;  2Q9Q B;  3CVR A;  3BQK A;  3KV9 A;  4UIG A;  5JRC A;  2B76 A;  2H3R A;  2WAU A;  3RPU A;  1OWA A;  4YSZ A;  4UV9 B;  4Q25 A;  2BKN A;  3I1A A;  2DL1 A;  3Q5D A;  4HWH A;  4H9P C;  3CWZ B;  2CM0 A;  3LK2 B;  4ANJ A;  3HL6 A;  2WU5 A;  5ABH A;  2FUP A;  4HFE A;  3UU5 A;  4JI6 T;  2MOZ A;  2NW9 A;  2V26 A;  3TLT A;  3F2E A;  5H6R B;  2DI4 A;  3U78 A;  5HWY A;  5LG4 A;  4IE0 A;  4X62 T;  3P4Q A;  5LA6 E;  5L47 A;  3AXJ B;  2GK9 A;  5JTG A;  5AQQ B;  4HFH A;  4DV1 T;  5L3F B;  2HH7 A;  2CXL A;  4BAY B;  5LGN B;  2CHO A;  3SFD A;  4JI1 T;  2X51 A;  3PTR B;  5HEO A;  5CJ5 A;  5JDF A;  4IDQ A;  2V7K A;  2CXD A;  3ZST A;  5LJM A;  3NWI A;  5AQT B;  3Q5W A;  4O4I E;  4Z91 A;  2J47 A;  3UUL A;  4DV2 T;  3N5L A;  4QH4 A;  3SFE A;  2XTL A;  5AQI B;  5KMG P;  1UK5 A; 
#chains in the Genus database with same CATH homology
 4HWF A;  4HWI B;  5AQH B;  3FZH B;  3M3Z B;  4HWD A;  5AQN B;  3FZL B;  5AQM B;  5AQP B;  5AQK B;  5AQT B;  3FZF B;  5AQU B;  5AQS B;  3FZM B;  1UGO A;  5AQF B;  4HWH A;  5AQJ B;  1M7K A;  1I6Z A;  5AQQ B;  1T7S A;  3FZK B;  5AQO B;  1HX1 B;  2D9D A;  3A8Y C;  4HWC A;  5AQR B;  3LDQ B;  5AQG B;  5AQV B;  5AQL B;  5AQI B;  1M62 A;  1UK5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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