5AQPB

Fragment-based screening of hsp70 sheds light on the functional role of atp-binding site residues
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
111
structure length
111
Chain Sequence
SNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
pubmed doi rcsb
molecule tags Chaperone
source organism Homo sapiens
molecule keywords HEAT SHOCK COGNATE 71 KDA PROTEIN
total genus 45
structure length 111
sequence length 111
chains with identical sequence D, F
ec nomenclature
pdb deposition date 2015-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02179 BAG BAG domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.58.120 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase; Chain G, domain 1 BAG domain 5aqpB00
3LDQB 1M7KA 1I6ZA 4HWCA 5AQRB 5AQVB 4HWFA 3FZMB 1UGOA 5AQFB 5AQLB 4HWIB 3FZHB 5AQUB 5AQMB 5AQQB 3M3ZB 2D9DA 1UK5A 3FZLB 4HWHA 5AQHB 4HWDA 3FZKB 1HX1B 1T7SA 5AQGB 5AQJB 1M62A 5AQSB 5AQTB 5AQIB 5AQKB 3A8YC 5AQNB 5AQOB 5AQPB 3FZFB
chains in the Genus database with same CATH superfamily
4FJOA 1I6ZA 4KHZF 4U7YA 5AQRB 4DIDB 3QUJA 3V5SA 5J2TE 3PU3A 2OLTA 5FKYA 4I55E 3UQ7A 5CA0E 1VRBA 2XM1A 1VOMA 2JRKA 2ZM0A 1HS7A 1JNRA 3FXEB 2BG9E 5L4HA 4LFAT 3N9MA 2X9HA 5LGTB 3LK2B 2BKOA 4U33A 3ZYKA 5AQVB 3TLTA 3JCFA 3TLSA 5AQMB 5AQQB 4KUMB 1IBMT 4X65T 4GKKT 4ZZCA 1ZEEA 2NOXA 4GKJT 5JR9C 2KINB 2LSKA 2PTFA 1NAFA 2WU2A 5L3EB 3UU3A 3BK9A 2J4GA 5ABFB 3H3MA 2DCFA 2DL1A 2WWUA 2KLQA 4ZXLA 3I9YA 4DV6T 5FMNA 5FP3A 3ZMSB 2CXFA 4HGAA 3EVYA 1XWMA 2YU1A 3FB2A 3M65A 4TWHA 4IDNA 4O4LE 2D5UA 1YXRA 4H63V 4H63H 2H88A 5ABGA 3ETVA 5AQGB 4YSYA 4IE5A 3AXJA 1YQ3A 2KXPB 3NRXA 3ZMUB 4YFSA 5FL1A 1D1CA 5LP6E 3O1HA 2M6IA 4LF7T 5ABFA 3PV0F 3HL6A 5CGMA 3RIFA 2VKDA 3B5MA 2KSRA 2FJDA 5ETWA 3AE2A 4H9RC 1HR0T 3HR0A 1N32T 1FIOA 2LSYA 5L47A 3P50A 3AE3A 4EEDA 2I59A 3ZT5A 3RGLA 3PURA 3B13A 3UUMA 5LG3A 2KWIB 3SRZA 4DVDA 1Y01A 4B3MT 2W4XA 2R6GF 4MLKA 4MHCA 5AQTB 5LHIB 1NWMX 3AAIA 3UU8A 3OVUA 3S4UA 5HXEA 4NPPA 4GIWA 2XAGB 4MALA 2MTQA 3PJAA 2LRLA 4ANJA 4IREA 4CXYA 2FJBA 4HWHA 4DV3T 4ZI3C 2KZ7B 3WAJA 2N1GA 4JV5T 5AQSB 2HPLA 5LJMA 4Q25A 4TWFA 4A56A 4EGWA 4TV8E 2M6BA 4PNIA 2ZM8A 3ZJ1A 1GQEA 3CX7B 4FI5A 4HFCA 4WBOA 3RYHE 4LFCT 2YEVC 3P4WA 3OPCA 2BDEA 1N33T 2IIUA 4YSZA 4NUVA 4V1Av 1CUNA 2MYSA 3KBUA 4G2AA 4QKNA 2D2SA 4P0AA 5LXTE 4LFBT 2X68A 1OEDB 5FVLA 4ASKA 4LMLA 3ONXA 4TZ4C 2EHOC 2IUBA 4DV4T 4ZI7E 3NZQA 4H9OC 3FZFB 4EZHA 2B76A 3UFEA 4CXWA 4EZ4A 3RKGA 2V7IA 4F8HA 4GK0E 4H9QC 1LVKA 2J62A 4TN7B 5FXZA 3AEBA 3RIUC 1OEDA 2A3DA 3IBPA 2VK9A 4HN9A 3CIRA 1WR0A 2CWYA 2FBWA 3MACA 3WAKA 5JDGA 3PUSA 5JVDE 2ZMAA 3RI5A 4DR6T 5DQVA 2UXDT 4YJ2E 5BMVE 2JQHA 4ILAA 1HCIA 1V9DA 2C5JA 2E2AA 5GONE 4EYUA 4IDOA 4DUYT 4OYKA 1T7SA 4DMWA 3B57A 4JI1T 3U3IA 3MZKB 4ZS3A 1VCSA 2IDOB 1AJ3A 2L8KA 4DUZT 4PAGA 5HAXA 4ADZA 2CMRA 4ISTA 4DBQA 2Q9QB 3J7Yq 3MKDA 4OYJA 1SHZC 2FJAA 4UV9B 3GN5B 1SUMB 3L3PA 4MBQA 1KNPA 3SOLA 1ZKEA 2BG9A 5EK2A 4EIWA 4KI0F 3K3OA 4YTMA 3RQWA 3UTKA 4CN1A 3AE8A 2RPAA 3ETUA 5AFUL 4WYVA 5LNKA 3BQKA 2W62A 4HWFA 4LF9T 2XQ7A 4G63A 3VR8A 3ZN0B 3DTOA 2VURA 5CJ5A 2JQKA 2Q9QA 3JC6C 4AQFA 2IW5B 1H7CA 3ZCJA 3NZPA 2DNXA 3GN5A 1XMOT 4PK5A 3ZYMA 4UVBB 4AISA 3KVBA 3C4XA 5C3JA 4LF8T 5AQFB 2L9QA 3Q5WA 5JQGE 1KFYA 1ZOYA 4BJNA 5JDLA 3PJAJ 2PJQA 3VRBA 4TWDA 4AKLA 3C98B 2MPKA 2DWKA 3TLUA 4IDQA 3Q9DA 4DNDA 2VB6A 4UVCB 4L5GA 4UV8B 1WRDA 5BR8T 4COFA 3O4XE 2X0LB 2LSGA 2BBJA 2NTYA 3L39A 3PUGA 2YDSA 2UUAT 2BS2A 3LDQB 2CXLA 4HWCA 4O2AE 3EDUA 3RYCE 2WSSV 3EDVA 4JEUB 1KK7A 3EAMA 4ILCA 1D1BA 2LM9A 2LLYA 2I6HA 5FVKA 2WQYA 3EUHA 4I4TE 3AAEB 1OEDE 4QX8B 3A5XA 1HFAA 3NRYA 3KBTA 2ODUA 4O2BE 5FYMA 2WMOA 1T72A 2WP9A 3E0ZA 3CQXC 3AAAB 1XNRT 4IHJE 1IJ5A 2LKHA 4QHOA 1X79A 2D0TA 1DU2A 2CBJA 5JR9A 3BQIA 1FEWA 3ZSSA 1MMAA 4UVAB 5IYZE 2E5LT 5L3CB 4PJLA 4NUUA 4E7SA 3RPUA 4HE8A 3ZPOA 2NR4A 1W9RA 2NW8A 2ZLYA 5F8PA 2IC6A 4B3ST 1FMWA 4GK5E 2X67A 3KDSE 3ABVA 1WCRA 5ABEA 1BR2A 1J5ET 2NW7A 3C4ZA 1UX4A 4IGUA 5FY0A 4JUYA 2WZIA 2VL0A 3Q5XA 1BR1A 1J5WA 2XAFB 3IHRA 3H37A 1IZNB 2V6YB 3LFMA 5F3JA 3N2KE 5KXJA 2BKNA 3KV5A 5L4EA 4U2YA 2WDQA 3QB5K 2VKOA 1U4QA 3ZMVB 4QX7B 3ZYLA 5HEUA 4JI2T 4PJMA 5KDMC 4O8SA 4TV9E 4HEAA 2FJEA 4H9PC 3AEFA 3AA0B 4F6RC 2K9AA 3RRWA 1WLXA 3FZKB 3RC3A 1MIYA 5JTGA 2X0HA 4UXNB 3SFDA 2QRXA 2V7LA 3ANWB 1UURA 4PJNA 3NKZA 1US7B 1X9BA 2EHOB 2NTXA 2A2FX 2UUBT 4DR3T 3SS1A 4EOZB 3UULA 2IMLA 5AQJB 4K0UA 2YU2A 2N9DA 4L0RA 5LHHB 4EV6A 3RF1A 4ZS2A 1S35A 3HKCE 4XBFB 3KINB 4ZHQE 2DLRA 1OWAA 3JADA 2CPTA 2EHOA 4JLEA 4IL4A 1T98A 3UU5A 2XQ4A 2XZEA 1Z0PA 3Q5DA 1WFDA 2K3WA 1D0ZA 1SE7A 3E22E 3C50A 5LGUB 5J0ZA 1HG2A 1LRZA 5L3FB 3K3NA 2UXBT 2K48A 2X51A 2LHRA 4HFIA 2ACZA 3DJBA 2D0UA 1YD8G 2VKHA 4IDZA 3RIUA 2NWBA 5FXVA 2E5VA 2AXDS 2LKGA 3CPZA 3PUYF 1O3XA 3FZHB 1NEKA 5LBMA 4ILUA 3PUQA 4OFZA 3CQGB 1Y64B 2LJLA 2K24A 3AB3B 3OYZA 3N9QA 1HNWT 3QOFA 1FJGT 3MK7C 3LSVA 5LB7B 3RHWA 2HN1A 2H3RA 3P4SA 1D0YA 4DR5T 3P4QA 3ZT7A 3T1YT 2P9BA 3P8CD 3FHNA 3VRAA 2YOEA 4ZEYA 4O4IE 2W2UA 4TNVA 4AKGA 5EZYE 4YXDA 4JI0T 3CQCB 2XQAA 2E8IA 3FBZA 1ZV4X 3VR9A 4DR7T 2WDVA 2LSIA 4DV2T 3UUBA 1MMGA 1E1HB 2UU9T 2W63A 3AVSA 3BQLA 2HPJA 2VVNA 2WBLA 3CVRA 3MA9A 3TLWA 4KMCA 4GYRA 4EYYR 2RP4A 4U74A 4I0UA 3SWHA 2HH7A 3EI0A 3UQ4A 1W0AA 3UT5E 2VQET 4I50E 2I0MA 1XDOA 4JBWF 3C51A 3P7IA 3MXZA 3UFGA 4HWDA 4CI3B 4JYAT 3VKHA 4CI1B 3O1JA 4IL9A 3CX8B 2XAHB 3LK42 2WCAA 5KX5E 2VQFT 2V7MA 4LMJA 5CFBA 2DI4A 4TX5A 3DP7A 4C91A 1E7PA 3IEEA 4U3CA 3CK6A 5HCMA 3FZLB 4B3TT 5LGNB 5FY1A 4HFBA 4UF0B 5FL0A 5FXWA 1M7KA 4QXHB 1XMQT 3N9PA 3F57A 4JI6T 2JQ9A 2VKJA 2X9WA 2E9XB 2IHR1 4J2CA 4KBMB 1UK5A 2MBGA 4BJMA 5JDHA 5HWXA 3ZT6A 4ZOLE 4UR9A 4HKAA 4WBNE 4WNKA 1XNQT 3ZEFB 2DWGA 3EHZA 5LJNA 2UXCT 4LF6T 4HFHA 2IC9A 3EABA 2H89A 4IE7A 4UF0A 2PBIA 1D0XA 2VASA 2W0GA 1IBKT 5LHGB 1WYBA 4ZI2D 2YDRA 3C4WA 2LE8A 1UUSA 1ZP0A 1YKEB 2ZM2A 3LK3B 2CEAA 3PU8A 3ZC1A 5AQNB 2BZBA 2Q9QD 5DQWA 5TAOA 4CN4A 3IF8B 4CN6A 5JDNA 4OX9T 2LOSA 2LOPA 3J9X1 5FXXA 2XHEB 2XQ9A 3AEAA 3ONLC 4LF4T 2UXNB 5HWYA 2JMKA 2IAKA 1KNZA 4AKRB 2PFVA 3JAFA 4OHFA 5HCJA 3K8PC 2CE7A 2CXDA 1HX8A 5LCYA 4Z90A 3GMIA 1G73A 3RRCA 2CLYC 1UCUA 3ZN1B 1W09A 1HTJF 2CHOA 2WM9A 4PK4A 3CX6B 3VKGA 5EK3A 2A72A 2X66A 2DHRA 4X20E 1E2AA 5IHYA 4P09A 4IT4A 4YHJA 4QWNB 5LMNT 4QH5A 5JDQA 2E9XC 4TUYE 1EZ3A 4ZZBA 3VHLA 3R6NA 2HN2A 1MIVA 2XQ6A 1KF6A 4GOUA 1IAPA 4K0KT 2D9DA 2Y8DA 1BR4A 1NENA 4WW0A 5IUXA 2QYWA 2JQQA 3CMLA 4GYSA 2PG8A 3F2EA 4XAXB 2LSJA 5HEJA 4N78D 5CB4E 2NW9A 3V5UA 3HKDE 4H9NC 4ERRA 2BS4A 4XZCA 4ISSA 3RLFF 3CKDA 2OA5A 3KV9A 3PUWF 4PFOA 1HNXT 3N5LA 3RQUA 2XY8B 3P4PA 4AKIA 3PTRB 1WYCA 3AE4A 4WZXA 2XTLA 2JPFA 1I94T 3RH3A 2W67A 2MAWA 3I0OA 5JREA 5AQIB 3ZMZB 4C90A 2ES0A 4X1KE 2YK0A 3C64A 3IA3A 2B1EA 2WU5A 1ZHCA 5J2UE 2ACXA 3QK6A 5AQLB 3QB5A 4AIUA 5DABA 5LG4A 1YQ4A 4ILBA 3L8RA 5FY7A 2GK9A 5IWAT 3I9WA 3ZKRA 3N9LA 4CXXA 3NVOA 2JMHA 3NBXX 5JDFA 2XAJB 1UX5A 3AE7A 1QLBA 2V26A 1MNEA 3O9XA 5JH7E 2V6YA 4JI3T 4O4JE 2AE9A 2JIWA 3ZMTB 4AXPA 3WI3A 2Z6EA 3AXJB 2XQ5A 5AQUB 2CA5A 5C2TA 2M67A 4QXBB 4CZZB 1XZYA 4ZI3D 2WMNA 3OKQA 2CRBA 3UU4A 2SPCA 2XUEA 1VCTA 3KFWX 4U2ZA 1MNDA 3D0TA 1R8IA 2CHNA 3ANWA 3U78A 5LBQB 3LJCA 2YINA 3LBXB 2BVMA 4EB6E 3AEDA 3R84B 4DR4T 2YN6A 2MOZA 3N2OA 5CA1E 2XQ8A 2LEHA 5KMGP 4KP3C 5HXRA 1HNZT 2XSBA 2J1DG 2V5CA 1HX1B 1N34T 2H7VC 3SFEA 2KNDA 2CWOA 4YTNA 2W00A 4JEHB 2KT9A 2W61A 2BS3A 1G8XA 3GWHA 5HYAA 2EHOD 5L3BB 1WR6A 3HI2A 4IE6A 5E0OA 1U5PA 3P4RA 2WDRA 2VWAA 3LBXA 3W15B 1M62A 4JI5T 3JAEA 3FBLA 3ZC0A 2CM0A 2G0UA 3I0QA 5M4YA 3TLVA 2KWHA 4MFRA 2KMFA 1LKXA 3PUVF 3A8YC 4X5TA 3O1IA 2BBHA 4DR2T 5JDMA 3N2GE 5HXHA 4YJ3E 4E7ZA 4PK6A 4NIQA 1LVFA 2WS3A 4I43B 3PUZF 3RYIE 3AE5A 4A98A 5HEOA 3PUXF 2X9XA 4U72A 3FXDB 4YHHT 4AKHA 4IE0A 1UGOA 4DBRA 4IIJE 1HF8A 4LMKA 3QNUA 3UUNA 5ABHA 2V7KA 2FUPA 3OTOT 4UIGA 3ZLIA 2V5DA 4EEBA 3PE0A 4HFDA 3AVRA 4EAHA 3AEEA 2LRKA 2LHNA 4A5XA 3RKOA 2XPKA 3PDYA 2YKSA 3NWIA 2F4VT 3T8OA 2C5IT 3AE6A 4X1IE 3VU7H 5AQOB 2WWVA 4DV0T 5L2LA 2V1DB 2ZM6T 4HWIB 1MIWA 3GA8A 3AECA 2XQ3A 5A1LA 4Z8XA 3HKEE 4AQYT 4PW8A 4DV1T 1W0BA 1CHUA 2A9UA 4YSXA 2UUCT 2CLYB 3JC6D 4KX6A 3FZMB 3MJXA 3KVAA 3A7MA 2V8SV 1IJ6A 4BAYB 4DV5T 4UEMA 2WB5A 2BG9B 2V7JA 4AQGA 2C0SA 4H9SE 2XASB 3RX6A 4U7IA 4BA9A 4KHPT 1FMVA 3N9OA 2XM2A 3K3QC 2HHHT 4P1NA 2V6XA 1BR0A 3KV4A 3E08A 5HEGA 2CBIA 5HXCA 5FNVE 5L3GB 4Z91A 3ZJ2A 2Y6XA 3PUAA 4L9IA 3K1SA 5EK4A 5JRCB 2RA1A 2VL8A 3H3AA 5LMUT 4DMVA 4O4HE 5HXSA 2Y48B 1QUUA 3AEGA 1Z8UA 3UUXB 2OV9A 2L3LA 3M3ZB 3Q2MA 4HFVA 3OYXA 4TNWA 4PFPA 4NXMT 1T8BA 1JNZA 1KEYA 1KNRA 1OEDC 4X1YE 5AQPB 1YKHB 5L3DB 2E9XA 4DO0A 2BKPA 4QH4A 1QSDA 3RC8A 5C8YE 5JRCA 4X62T 4IE4A 3AE1A 4PJJA 3T1HT 2QGSA 5LYJE 5H6RB 3LG7A 2X9YA 3ONJA 2BVLA 5LOVE 2XAQB 3HA4A 3QC9A 2WZHA 1B7TA 3RYFE 1S94A 2N2NA 3UU6A 2E9XD 3OJAA 3AE9A 3X1DA 3AA7B 1IBLT 5HEHA 2K5BB 1HG5A 2UXXB 1OXZA 3RIAA 3G06A 4YT0A 3HKBE 5F5WA 4A97A 1XDPA 2XQYA 5DJQC 4JI7T 2J47A 2QVAA 4QH1A 2C5KT 2XSAA 2QA7A 1SA0E 2YDQA 2BG9C 4X64T 3N9NA 4YLHA 4CQIA 5JR9B 4X66T 4YTPA 1MMDA 2JJ9A 3KV6A 1N36T 2ODVA 3F31A 1YW0A 4ZI2C 4AI6A 5AQKB 5J1GA 2LM2A 5H6QB 4DV7T 4B6XA 4P0BA 1D1AA 3ESLA 4HFEA 4U31A 2LT3A 4CI2B 2W66A 2Q9QC 3AA6B 5AQHB 2WY2A 3L09A 4JI8T 4AQFC 1J1JA 4B3RT 2WAUA 4UELA 3I1AA 5ADXL 3TKLB 4EXTA 4DR1T 1MMNA 4QXCB 4HTEA 2NP9A 4OK0A 1L0VA 4IDPA 3Q5EA 3ZSTA 2XJ7A 2VVSA 3CWZB 2H7OA 4YY3T 4LF5T 3AA1B 2CCQA 4M1PA 3ZCIA 4NXNT 5LA6E 3OBVE 2X0YA 4JI4T
chains in the Genus database with same CATH topology
3LDQB 1M7KA 1I6ZA 4HWCA 5AQRB 5AQVB 4HWFA 3FZMB 1UGOA 5AQFB 5AQLB 4HWIB 3FZHB 5AQUB 5AQMB 5AQQB 3M3ZB 2D9DA 1UK5A 3FZLB 4HWHA 5AQHB 4HWDA 3FZKB 1HX1B 1T7SA 5AQGB 5AQJB 1M62A 5AQSB 5AQTB 5AQIB 5AQKB 3A8YC 5AQNB 5AQOB 5AQPB 3FZFB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LDQ B;  1M7K A;  1I6Z A;  4HWC A;  5AQR B;  5AQV B;  4HWF A;  3FZM B;  1UGO A;  5AQF B;  5AQL B;  4HWI B;  3FZH B;  5AQU B;  5AQM B;  5AQQ B;  3M3Z B;  2D9D A;  1UK5 A;  3FZL B;  4HWH A;  5AQH B;  4HWD A;  3FZK B;  1HX1 B;  1T7S A;  5AQG B;  5AQJ B;  1M62 A;  5AQS B;  5AQT B;  5AQI B;  5AQK B;  3A8Y C;  5AQN B;  5AQO B;  5AQP B;  3FZF B; 
#chains in the Genus database with same CATH topology
 4FJO A;  1I6Z A;  4KHZ F;  4U7Y A;  5AQR B;  4DID B;  3QUJ A;  3V5S A;  5J2T E;  3PU3 A;  2OLT A;  5FKY A;  4I55 E;  3UQ7 A;  5CA0 E;  1VRB A;  2XM1 A;  1VOM A;  2JRK A;  2ZM0 A;  1HS7 A;  1JNR A;  3FXE B;  2BG9 E;  5L4H A;  4LFA T;  3N9M A;  2X9H A;  5LGT B;  3LK2 B;  2BKO A;  4U33 A;  3ZYK A;  5AQV B;  3TLT A;  3JCF A;  3TLS A;  5AQM B;  5AQQ B;  4KUM B;  1IBM T;  4X65 T;  4GKK T;  4ZZC A;  1ZEE A;  2NOX A;  4GKJ T;  5JR9 C;  2KIN B;  2LSK A;  2PTF A;  1NAF A;  2WU2 A;  5L3E B;  3UU3 A;  3BK9 A;  2J4G A;  5ABF B;  3H3M A;  2DCF A;  2DL1 A;  2WWU A;  2KLQ A;  4ZXL A;  3I9Y A;  4DV6 T;  5FMN A;  5FP3 A;  3ZMS B;  2CXF A;  4HGA A;  3EVY A;  1XWM A;  2YU1 A;  3FB2 A;  3M65 A;  4TWH A;  4IDN A;  4O4L E;  2D5U A;  1YXR A;  4H63 V;  4H63 H;  2H88 A;  5ABG A;  3ETV A;  5AQG B;  4YSY A;  4IE5 A;  3AXJ A;  1YQ3 A;  2KXP B;  3NRX A;  3ZMU B;  4YFS A;  5FL1 A;  1D1C A;  5LP6 E;  3O1H A;  2M6I A;  4LF7 T;  5ABF A;  3PV0 F;  3HL6 A;  5CGM A;  3RIF A;  2VKD A;  3B5M A;  2KSR A;  2FJD A;  5ETW A;  3AE2 A;  4H9R C;  1HR0 T;  3HR0 A;  1N32 T;  1FIO A;  2LSY A;  5L47 A;  3P50 A;  3AE3 A;  4EED A;  2I59 A;  3ZT5 A;  3RGL A;  3PUR A;  3B13 A;  3UUM A;  5LG3 A;  2KWI B;  3SRZ A;  4DVD A;  1Y01 A;  4B3M T;  2W4X A;  2R6G F;  4MLK A;  4MHC A;  5AQT B;  5LHI B;  1NWM X;  3AAI A;  3UU8 A;  3OVU A;  3S4U A;  5HXE A;  4NPP A;  4GIW A;  2XAG B;  4MAL A;  2MTQ A;  3PJA A;  2LRL A;  4ANJ A;  4IRE A;  4CXY A;  2FJB A;  4HWH A;  4DV3 T;  4ZI3 C;  2KZ7 B;  3WAJ A;  2N1G A;  4JV5 T;  5AQS B;  2HPL A;  5LJM A;  4Q25 A;  4TWF A;  4A56 A;  4EGW A;  4TV8 E;  2M6B A;  4PNI A;  2ZM8 A;  3ZJ1 A;  1GQE A;  3CX7 B;  4FI5 A;  4HFC A;  4WBO A;  3RYH E;  4LFC T;  2YEV C;  3P4W A;  3OPC A;  2BDE A;  1N33 T;  2IIU A;  4YSZ A;  4NUV A;  4V1A v;  1CUN A;  2MYS A;  3KBU A;  4G2A A;  4QKN A;  2D2S A;  4P0A A;  5LXT E;  4LFB T;  2X68 A;  1OED B;  5FVL A;  4ASK A;  4LML A;  3ONX A;  4TZ4 C;  2EHO C;  2IUB A;  4DV4 T;  4ZI7 E;  3NZQ A;  4H9O C;  3FZF B;  4EZH A;  2B76 A;  3UFE A;  4CXW A;  4EZ4 A;  3RKG A;  2V7I A;  4F8H A;  4GK0 E;  4H9Q C;  1LVK A;  2J62 A;  4TN7 B;  5FXZ A;  3AEB A;  3RIU C;  1OED A;  2A3D A;  3IBP A;  2VK9 A;  4HN9 A;  3CIR A;  1WR0 A;  2CWY A;  2FBW A;  3MAC A;  3WAK A;  5JDG A;  3PUS A;  5JVD E;  2ZMA A;  3RI5 A;  4DR6 T;  5DQV A;  2UXD T;  4YJ2 E;  5BMV E;  2JQH A;  4ILA A;  1HCI A;  1V9D A;  2C5J A;  2E2A A;  5GON E;  4EYU A;  4IDO A;  4DUY T;  4OYK A;  1T7S A;  4DMW A;  3B57 A;  4JI1 T;  3U3I A;  3MZK B;  4ZS3 A;  1VCS A;  2IDO B;  1AJ3 A;  2L8K A;  4DUZ T;  4PAG A;  5HAX A;  4ADZ A;  2CMR A;  4IST A;  4DBQ A;  2Q9Q B;  3J7Y q;  3MKD A;  4OYJ A;  1SHZ C;  2FJA A;  4UV9 B;  3GN5 B;  1SUM B;  3L3P A;  4MBQ A;  1KNP A;  3SOL A;  1ZKE A;  2BG9 A;  5EK2 A;  4EIW A;  4KI0 F;  3K3O A;  4YTM A;  3RQW A;  3UTK A;  4CN1 A;  3AE8 A;  2RPA A;  3ETU A;  5AFU L;  4WYV A;  5LNK A;  3BQK A;  2W62 A;  4HWF A;  4LF9 T;  2XQ7 A;  4G63 A;  3VR8 A;  3ZN0 B;  3DTO A;  2VUR A;  5CJ5 A;  2JQK A;  2Q9Q A;  3JC6 C;  4AQF A;  2IW5 B;  1H7C A;  3ZCJ A;  3NZP A;  2DNX A;  3GN5 A;  1XMO T;  4PK5 A;  3ZYM A;  4UVB B;  4AIS A;  3KVB A;  3C4X A;  5C3J A;  4LF8 T;  5AQF B;  2L9Q A;  3Q5W A;  5JQG E;  1KFY A;  1ZOY A;  4BJN A;  5JDL A;  3PJA J;  2PJQ A;  3VRB A;  4TWD A;  4AKL A;  3C98 B;  2MPK A;  2DWK A;  3TLU A;  4IDQ A;  3Q9D A;  4DND A;  2VB6 A;  4UVC B;  4L5G A;  4UV8 B;  1WRD A;  5BR8 T;  4COF A;  3O4X E;  2X0L B;  2LSG A;  2BBJ A;  2NTY A;  3L39 A;  3PUG A;  2YDS A;  2UUA T;  2BS2 A;  3LDQ B;  2CXL A;  4HWC A;  4O2A E;  3EDU A;  3RYC E;  2WSS V;  3EDV A;  4JEU B;  1KK7 A;  3EAM A;  4ILC A;  1D1B A;  2LM9 A;  2LLY A;  2I6H A;  5FVK A;  2WQY A;  3EUH A;  4I4T E;  3AAE B;  1OED E;  4QX8 B;  3A5X A;  1HFA A;  3NRY A;  3KBT A;  2ODU A;  4O2B E;  5FYM A;  2WMO A;  1T72 A;  2WP9 A;  3E0Z A;  3CQX C;  3AAA B;  1XNR T;  4IHJ E;  1IJ5 A;  2LKH A;  4QHO A;  1X79 A;  2D0T A;  1DU2 A;  2CBJ A;  5JR9 A;  3BQI A;  1FEW A;  3ZSS A;  1MMA A;  4UVA B;  5IYZ E;  2E5L T;  5L3C B;  4PJL A;  4NUU A;  4E7S A;  3RPU A;  4HE8 A;  3ZPO A;  2NR4 A;  1W9R A;  2NW8 A;  2ZLY A;  5F8P A;  2IC6 A;  4B3S T;  1FMW A;  4GK5 E;  2X67 A;  3KDS E;  3ABV A;  1WCR A;  5ABE A;  1BR2 A;  1J5E T;  2NW7 A;  3C4Z A;  1UX4 A;  4IGU A;  5FY0 A;  4JUY A;  2WZI A;  2VL0 A;  3Q5X A;  1BR1 A;  1J5W A;  2XAF B;  3IHR A;  3H37 A;  1IZN B;  2V6Y B;  3LFM A;  5F3J A;  3N2K E;  5KXJ A;  2BKN A;  3KV5 A;  5L4E A;  4U2Y A;  2WDQ A;  3QB5 K;  2VKO A;  1U4Q A;  3ZMV B;  4QX7 B;  3ZYL A;  5HEU A;  4JI2 T;  4PJM A;  5KDM C;  4O8S A;  4TV9 E;  4HEA A;  2FJE A;  4H9P C;  3AEF A;  3AA0 B;  4F6R C;  2K9A A;  3RRW A;  1WLX A;  3FZK B;  3RC3 A;  1MIY A;  5JTG A;  2X0H A;  4UXN B;  3SFD A;  2QRX A;  2V7L A;  3ANW B;  1UUR A;  4PJN A;  3NKZ A;  1US7 B;  1X9B A;  2EHO B;  2NTX A;  2A2F X;  2UUB T;  4DR3 T;  3SS1 A;  4EOZ B;  3UUL A;  2IML A;  5AQJ B;  4K0U A;  2YU2 A;  2N9D A;  4L0R A;  5LHH B;  4EV6 A;  3RF1 A;  4ZS2 A;  1S35 A;  3HKC E;  4XBF B;  3KIN B;  4ZHQ E;  2DLR A;  1OWA A;  3JAD A;  2CPT A;  2EHO A;  4JLE A;  4IL4 A;  1T98 A;  3UU5 A;  2XQ4 A;  2XZE A;  1Z0P A;  3Q5D A;  1WFD A;  2K3W A;  1D0Z A;  1SE7 A;  3E22 E;  3C50 A;  5LGU B;  5J0Z A;  1HG2 A;  1LRZ A;  5L3F B;  3K3N A;  2UXB T;  2K48 A;  2X51 A;  2LHR A;  4HFI A;  2ACZ A;  3DJB A;  2D0U A;  1YD8 G;  2VKH A;  4IDZ A;  3RIU A;  2NWB A;  5FXV A;  2E5V A;  2AXD S;  2LKG A;  3CPZ A;  3PUY F;  1O3X A;  3FZH B;  1NEK A;  5LBM A;  4ILU A;  3PUQ A;  4OFZ A;  3CQG B;  1Y64 B;  2LJL A;  2K24 A;  3AB3 B;  3OYZ A;  3N9Q A;  1HNW T;  3QOF A;  1FJG T;  3MK7 C;  3LSV A;  5LB7 B;  3RHW A;  2HN1 A;  2H3R A;  3P4S A;  1D0Y A;  4DR5 T;  3P4Q A;  3ZT7 A;  3T1Y T;  2P9B A;  3P8C D;  3FHN A;  3VRA A;  2YOE A;  4ZEY A;  4O4I E;  2W2U A;  4TNV A;  4AKG A;  5EZY E;  4YXD A;  4JI0 T;  3CQC B;  2XQA A;  2E8I A;  3FBZ A;  1ZV4 X;  3VR9 A;  4DR7 T;  2WDV A;  2LSI A;  4DV2 T;  3UUB A;  1MMG A;  1E1H B;  2UU9 T;  2W63 A;  3AVS A;  3BQL A;  2HPJ A;  2VVN A;  2WBL A;  3CVR A;  3MA9 A;  3TLW A;  4KMC A;  4GYR A;  4EYY R;  2RP4 A;  4U74 A;  4I0U A;  3SWH A;  2HH7 A;  3EI0 A;  3UQ4 A;  1W0A A;  3UT5 E;  2VQE T;  4I50 E;  2I0M A;  1XDO A;  4JBW F;  3C51 A;  3P7I A;  3MXZ A;  3UFG A;  4HWD A;  4CI3 B;  4JYA T;  3VKH A;  4CI1 B;  3O1J A;  4IL9 A;  3CX8 B;  2XAH B;  3LK4 2;  2WCA A;  5KX5 E;  2VQF T;  2V7M A;  4LMJ A;  5CFB A;  2DI4 A;  4TX5 A;  3DP7 A;  4C91 A;  1E7P A;  3IEE A;  4U3C A;  3CK6 A;  5HCM A;  3FZL B;  4B3T T;  5LGN B;  5FY1 A;  4HFB A;  4UF0 B;  5FL0 A;  5FXW A;  1M7K A;  4QXH B;  1XMQ T;  3N9P A;  3F57 A;  4JI6 T;  2JQ9 A;  2VKJ A;  2X9W A;  2E9X B;  2IHR 1;  4J2C A;  4KBM B;  1UK5 A;  2MBG A;  4BJM A;  5JDH A;  5HWX A;  3ZT6 A;  4ZOL E;  4UR9 A;  4HKA A;  4WBN E;  4WNK A;  1XNQ T;  3ZEF B;  2DWG A;  3EHZ A;  5LJN A;  2UXC T;  4LF6 T;  4HFH A;  2IC9 A;  3EAB A;  2H89 A;  4IE7 A;  4UF0 A;  2PBI A;  1D0X A;  2VAS A;  2W0G A;  1IBK T;  5LHG B;  1WYB A;  4ZI2 D;  2YDR A;  3C4W A;  2LE8 A;  1UUS A;  1ZP0 A;  1YKE B;  2ZM2 A;  3LK3 B;  2CEA A;  3PU8 A;  3ZC1 A;  5AQN B;  2BZB A;  2Q9Q D;  5DQW A;  5TAO A;  4CN4 A;  3IF8 B;  4CN6 A;  5JDN A;  4OX9 T;  2LOS A;  2LOP A;  3J9X 1;  5FXX A;  2XHE B;  2XQ9 A;  3AEA A;  3ONL C;  4LF4 T;  2UXN B;  5HWY A;  2JMK A;  2IAK A;  1KNZ A;  4AKR B;  2PFV A;  3JAF A;  4OHF A;  5HCJ A;  3K8P C;  2CE7 A;  2CXD A;  1HX8 A;  5LCY A;  4Z90 A;  3GMI A;  1G73 A;  3RRC A;  2CLY C;  1UCU A;  3ZN1 B;  1W09 A;  1HTJ F;  2CHO A;  2WM9 A;  4PK4 A;  3CX6 B;  3VKG A;  5EK3 A;  2A72 A;  2X66 A;  2DHR A;  4X20 E;  1E2A A;  5IHY A;  4P09 A;  4IT4 A;  4YHJ A;  4QWN B;  5LMN T;  4QH5 A;  5JDQ A;  2E9X C;  4TUY E;  1EZ3 A;  4ZZB A;  3VHL A;  3R6N A;  2HN2 A;  1MIV A;  2XQ6 A;  1KF6 A;  4GOU A;  1IAP A;  4K0K T;  2D9D A;  2Y8D A;  1BR4 A;  1NEN A;  4WW0 A;  5IUX A;  2QYW A;  2JQQ A;  3CML A;  4GYS A;  2PG8 A;  3F2E A;  4XAX B;  2LSJ A;  5HEJ A;  4N78 D;  5CB4 E;  2NW9 A;  3V5U A;  3HKD E;  4H9N C;  4ERR A;  2BS4 A;  4XZC A;  4ISS A;  3RLF F;  3CKD A;  2OA5 A;  3KV9 A;  3PUW F;  4PFO A;  1HNX T;  3N5L A;  3RQU A;  2XY8 B;  3P4P A;  4AKI A;  3PTR B;  1WYC A;  3AE4 A;  4WZX A;  2XTL A;  2JPF A;  1I94 T;  3RH3 A;  2W67 A;  2MAW A;  3I0O A;  5JRE A;  5AQI B;  3ZMZ B;  4C90 A;  2ES0 A;  4X1K E;  2YK0 A;  3C64 A;  3IA3 A;  2B1E A;  2WU5 A;  1ZHC A;  5J2U E;  2ACX A;  3QK6 A;  5AQL B;  3QB5 A;  4AIU A;  5DAB A;  5LG4 A;  1YQ4 A;  4ILB A;  3L8R A;  5FY7 A;  2GK9 A;  5IWA T;  3I9W A;  3ZKR A;  3N9L A;  4CXX A;  3NVO A;  2JMH A;  3NBX X;  5JDF A;  2XAJ B;  1UX5 A;  3AE7 A;  1QLB A;  2V26 A;  1MNE A;  3O9X A;  5JH7 E;  2V6Y A;  4JI3 T;  4O4J E;  2AE9 A;  2JIW A;  3ZMT B;  4AXP A;  3WI3 A;  2Z6E A;  3AXJ B;  2XQ5 A;  5AQU B;  2CA5 A;  5C2T A;  2M67 A;  4QXB B;  4CZZ B;  1XZY A;  4ZI3 D;  2WMN A;  3OKQ A;  2CRB A;  3UU4 A;  2SPC A;  2XUE A;  1VCT A;  3KFW X;  4U2Z A;  1MND A;  3D0T A;  1R8I A;  2CHN A;  3ANW A;  3U78 A;  5LBQ B;  3LJC A;  2YIN A;  3LBX B;  2BVM A;  4EB6 E;  3AED A;  3R84 B;  4DR4 T;  2YN6 A;  2MOZ A;  3N2O A;  5CA1 E;  2XQ8 A;  2LEH A;  5KMG P;  4KP3 C;  5HXR A;  1HNZ T;  2XSB A;  2J1D G;  2V5C A;  1HX1 B;  1N34 T;  2H7V C;  3SFE A;  2KND A;  2CWO A;  4YTN A;  2W00 A;  4JEH B;  2KT9 A;  2W61 A;  2BS3 A;  1G8X A;  3GWH A;  5HYA A;  2EHO D;  5L3B B;  1WR6 A;  3HI2 A;  4IE6 A;  5E0O A;  1U5P A;  3P4R A;  2WDR A;  2VWA A;  3LBX A;  3W15 B;  1M62 A;  4JI5 T;  3JAE A;  3FBL A;  3ZC0 A;  2CM0 A;  2G0U A;  3I0Q A;  5M4Y A;  3TLV A;  2KWH A;  4MFR A;  2KMF A;  1LKX A;  3PUV F;  3A8Y C;  4X5T A;  3O1I A;  2BBH A;  4DR2 T;  5JDM A;  3N2G E;  5HXH A;  4YJ3 E;  4E7Z A;  4PK6 A;  4NIQ A;  1LVF A;  2WS3 A;  4I43 B;  3PUZ F;  3RYI E;  3AE5 A;  4A98 A;  5HEO A;  3PUX F;  2X9X A;  4U72 A;  3FXD B;  4YHH T;  4AKH A;  4IE0 A;  1UGO A;  4DBR A;  4IIJ E;  1HF8 A;  4LMK A;  3QNU A;  3UUN A;  5ABH A;  2V7K A;  2FUP A;  3OTO T;  4UIG A;  3ZLI A;  2V5D A;  4EEB A;  3PE0 A;  4HFD A;  3AVR A;  4EAH A;  3AEE A;  2LRK A;  2LHN A;  4A5X A;  3RKO A;  2XPK A;  3PDY A;  2YKS A;  3NWI A;  2F4V T;  3T8O A;  2C5I T;  3AE6 A;  4X1I E;  3VU7 H;  5AQO B;  2WWV A;  4DV0 T;  5L2L A;  2V1D B;  2ZM6 T;  4HWI B;  1MIW A;  3GA8 A;  3AEC A;  2XQ3 A;  5A1L A;  4Z8X A;  3HKE E;  4AQY T;  4PW8 A;  4DV1 T;  1W0B A;  1CHU A;  2A9U A;  4YSX A;  2UUC T;  2CLY B;  3JC6 D;  4KX6 A;  3FZM B;  3MJX A;  3KVA A;  3A7M A;  2V8S V;  1IJ6 A;  4BAY B;  4DV5 T;  4UEM A;  2WB5 A;  2BG9 B;  2V7J A;  4AQG A;  2C0S A;  4H9S E;  2XAS B;  3RX6 A;  4U7I A;  4BA9 A;  4KHP T;  1FMV A;  3N9O A;  2XM2 A;  3K3Q C;  2HHH T;  4P1N A;  2V6X A;  1BR0 A;  3KV4 A;  3E08 A;  5HEG A;  2CBI A;  5HXC A;  5FNV E;  5L3G B;  4Z91 A;  3ZJ2 A;  2Y6X A;  3PUA A;  4L9I A;  3K1S A;  5EK4 A;  5JRC B;  2RA1 A;  2VL8 A;  3H3A A;  5LMU T;  4DMV A;  4O4H E;  5HXS A;  2Y48 B;  1QUU A;  3AEG A;  1Z8U A;  3UUX B;  2OV9 A;  2L3L A;  3M3Z B;  3Q2M A;  4HFV A;  3OYX A;  4TNW A;  4PFP A;  4NXM T;  1T8B A;  1JNZ A;  1KEY A;  1KNR A;  1OED C;  4X1Y E;  5AQP B;  1YKH B;  5L3D B;  2E9X A;  4DO0 A;  2BKP A;  4QH4 A;  1QSD A;  3RC8 A;  5C8Y E;  5JRC A;  4X62 T;  4IE4 A;  3AE1 A;  4PJJ A;  3T1H T;  2QGS A;  5LYJ E;  5H6R B;  3LG7 A;  2X9Y A;  3ONJ A;  2BVL A;  5LOV E;  2XAQ B;  3HA4 A;  3QC9 A;  2WZH A;  1B7T A;  3RYF E;  1S94 A;  2N2N A;  3UU6 A;  2E9X D;  3OJA A;  3AE9 A;  3X1D A;  3AA7 B;  1IBL T;  5HEH A;  2K5B B;  1HG5 A;  2UXX B;  1OXZ A;  3RIA A;  3G06 A;  4YT0 A;  3HKB E;  5F5W A;  4A97 A;  1XDP A;  2XQY A;  5DJQ C;  4JI7 T;  2J47 A;  2QVA A;  4QH1 A;  2C5K T;  2XSA A;  2QA7 A;  1SA0 E;  2YDQ A;  2BG9 C;  4X64 T;  3N9N A;  4YLH A;  4CQI A;  5JR9 B;  4X66 T;  4YTP A;  1MMD A;  2JJ9 A;  3KV6 A;  1N36 T;  2ODV A;  3F31 A;  1YW0 A;  4ZI2 C;  4AI6 A;  5AQK B;  5J1G A;  2LM2 A;  5H6Q B;  4DV7 T;  4B6X A;  4P0B A;  1D1A A;  3ESL A;  4HFE A;  4U31 A;  2LT3 A;  4CI2 B;  2W66 A;  2Q9Q C;  3AA6 B;  5AQH B;  2WY2 A;  3L09 A;  4JI8 T;  4AQF C;  1J1J A;  4B3R T;  2WAU A;  4UEL A;  3I1A A;  5ADX L;  3TKL B;  4EXT A;  4DR1 T;  1MMN A;  4QXC B;  4HTE A;  2NP9 A;  4OK0 A;  1L0V A;  4IDP A;  3Q5E A;  3ZST A;  2XJ7 A;  2VVS A;  3CWZ B;  2H7O A;  4YY3 T;  4LF5 T;  3AA1 B;  2CCQ A;  4M1P A;  3ZCI A;  4NXN T;  5LA6 E;  3OBV E;  2X0Y A;  4JI4 T; 
#chains in the Genus database with same CATH homology
 3LDQ B;  1M7K A;  1I6Z A;  4HWC A;  5AQR B;  5AQV B;  4HWF A;  3FZM B;  1UGO A;  5AQF B;  5AQL B;  4HWI B;  3FZH B;  5AQU B;  5AQM B;  5AQQ B;  3M3Z B;  2D9D A;  1UK5 A;  3FZL B;  4HWH A;  5AQH B;  4HWD A;  3FZK B;  1HX1 B;  1T7S A;  5AQG B;  5AQJ B;  1M62 A;  5AQS B;  5AQT B;  5AQI B;  5AQK B;  3A8Y C;  5AQN B;  5AQO B;  5AQP B;  3FZF B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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