3FZLB

Crystal structures of hsc70/bag1 in complex with small molecule inhibitors
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
111
structure length
111
Chain Sequence
GNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design
pubmed doi rcsb
molecule tags Chaperone
source organism Homo sapiens
molecule keywords Heat shock cognate 71 kDa protein
total genus 48
structure length 111
sequence length 111
ec nomenclature
pdb deposition date 2009-01-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02179 BAG BAG domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.58.120 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase; Chain G, domain 1 BAG domain 3fzlB00
1UK5A 5AQHB 5AQRB 5AQGB 5AQIB 5AQOB 1UGOA 3M3ZB 3FZKB 1M62A 5AQKB 5AQMB 5AQLB 5AQUB 3A8YC 3FZFB 1HX1B 4HWDA 5AQQB 5AQNB 1I6ZA 3FZLB 4HWIB 5AQJB 2D9DA 4HWFA 5AQFB 1M7KA 4HWCA 3FZMB 5AQPB 3LDQB 1T7SA 5AQSB 3FZHB 5AQTB 5AQVB 4HWHA
chains in the Genus database with same CATH superfamily
3ZMTB 4YT0A 2V26A 5AQKB 2BG9B 2K48A 4LF4T 4IL4A 2X51A 4MHCA 3C98B 4WW0A 2LRLA 2E9XA 3QK6A 4OYJA 3HI2A 3AE2A 2B76A 4HE8A 1MMGA 2XUEA 4EZHA 4JI6T 1D0ZA 1XWMA 4UIGA 1R8IA 5L4HA 2LJLA 2YKSA 5CA1E 2CBJA 2ODUA 2V5CA 4DV4T 5FP3A 4G63A 1I6ZA 3HKBE 3OTOT 1HS7A 2WS3A 2V5DA 4K0UA 2V7MA 3PJAA 4EGWA 2LSJA 4PJLA 4DR4T 3AAEB 3AEGA 2WM9A 2E9XC 2DHRA 3UUNA 3I0OA 3LK3B 3K3QC 4H9SE 1EZ3A 2W67A 4HFEA 2WWUA 5KMGP 2LSIA 5JDHA 1D0XA 1XNRT 2XQ9A 2MYSA 2A2FX 4TV8E 2WU2A 4NUUA 2FJDA 3P50A 1T98A 3AAAB 2DLRA 3O1IA 3OPCA 5JQGE 3R84B 3EAMA 3ABVA 4DR7T 5JRCA 4P0BA 5H6RB 2PFVA 2QGSA 2UXXB 3N9MA 2BVMA 3UFEA 3C50A 5L3CB 3P4WA 3PUSA 2Q9QA 2X9XA 3K8PC 1HFAA 2JPFA 4IDPA 1OWAA 5JDGA 2VKOA 2V7JA 1HNXT 3KVAA 5AQPB 3HL6A 4DIDB 3AE4A 2NW9A 4DR3T 1OEDA 5LNKA 1UCUA 2W0GA 2Z6EA 4ZHQE 5L2LA 4O4HE 4O4LE 5L3GB 3O9XA 2HN1A 2XAJB 2Q9QC 2GK9A 1U4QA 5JDNA 2H7VC 2C5JA 3OYXA 3ZSSA 3NVOA 2QA7A 3ZMSB 2UU9T 2LKGA 4AQFC 3N5LA 4ZEYA 4TWDA 4V1Av 1NAFA 1MMDA 3GMIA 4QH1A 2UXNB 1N34T 4IDQA 2BKPA 5BR8T 1ZV4X 4HWFA 4HEAA 3H3MA 4B3TT 4QKNA 2UXDT 3Q2MA 4JBWF 5IHYA 1KK7A 4TX5A 5C2TA 1HTJF 3NRXA 1ZKEA 2NP9A 2NTXA 2QYWA 3RYIE 3KFWX 3AE6A 4UELA 4H63H 2NR4A 2LEHA 5LGUB 4DUZT 4WNKA 1WLXA 5JH7E 3JC6C 4ILUA 1I94T 1E1HB 2M6IA 1WRDA 3RYCE 2XASB 2ZM0A 3ZSTA 4DV7T 2CLYC 4HTEA 3VRAA 2XQ4A 4IE0A 4P09A 3PUZF 3PUQA 4E7ZA 2CA5A 3MJXA 2KT9A 4M1PA 4NPPA 3J9X1 4UVAB 4CN1A 3FBLA 3GN5B 4AKLA 3WAJA 1D1CA 4IIJE 2D2SA 4U33A 4EAHA 2XM1A 2FJBA 1HF8A 3UTKA 2CMRA 3UFGA 3CKDA 4KP3C 5HAXA 2MBGA 5AQNB 5FVLA 2YDSA 4HFVA 5JR9B 3O4XE 1E2AA 3L3PA 3KDSE 3OKQA 3FZMB 4AKHA 2LOSA 4OK0A 2JIWA 4OHFA 4IDNA 3ETVA 3FZFB 1ZHCA 3ZMVB 2I0MA 2JMHA 3CQXC 4I43B 4OYKA 3NZPA 4EOZB 1LVKA 3DP7A 2XZEA 2RA1A 2CXLA 4QX8B 1NWMX 5L4EA 3MZKB 2WAUA 3FXEB 4JEUB 4PJJA 4HWIB 3PU8A 1MIVA 3B13A 3RKOA 2XAQB 4B3RT 3RX6A 4F8HA 1WCRA 3C4ZA 3AECA 4DV3T 1UK5A 2HPLA 2VL8A 4GOUA 4AXPA 2B1EA 3QOFA 3B57A 4O4JE 3RIFA 4O8SA 2NW8A 4YTNA 3ZLIA 3CK6A 2EHOB 4LF9T 2HN2A 2LE8A 1MNEA 1KNPA 3LJCA 3EDUA 5AFUL 5LHIB 3AXJB 1FJGT 3FXDB 3IHRA 1W0AA 2LSGA 5ADXL 5FL0A 4U2YA 3O1JA 5LGTB 3RGLA 2DWKA 3MK7C 2CRBA 4YFSA 4LF8T 2V7LA 2W4XA 4GYSA 3A8YC 1BR1A 3EUHA 4U74A 3ZN0B 2VASA 4IREA 2HPJA 4Z90A 2CE7A 2D9DA 3O1HA 2L9QA 3VR9A 2XAFB 1M7KA 1O3XA 2WZIA 3HR0A 2ACXA 2JMKA 4DBQA 2OLTA 4YSXA 4ZZBA 3ONLC 2JQHA 3VHLA 4AI6A 3AAIA 4GK0E 5ABFA 4X66T 4CI1B 3AA0B 2NOXA 4YJ2E 3SRZA 4ILCA 2H88A 5LJMA 3QNUA 2MAWA 3RHWA 1FMWA 2CPTA 3EI0A 2LKHA 4ZXLA 4JLEA 5AQOB 1D1AA 5FYMA 2XQ5A 4JEHB 5HXSA 2A72A 2ZM2A 4X64T 1V9DA 1Z8UA 3JAEA 3NWIA 2XAGB 4H9NC 5AQTB 1BR4A 1X9BA 3UQ7A 5L3DB 3ZPOA 3FZKB 4O4IE 5FY1A 2BG9E 2L3LA 4JYAT 2P9BA 3IA3A 1W09A 3LBXB 5LHGB 3V5SA 2LM9A 3ZKRA 4YHJA 3OVUA 4YSZA 4QXCB 2E2AA 3HKDE 1W0BA 5AQLB 4PK6A 4A56A 5F8PA 2V6YA 3ZC0A 4U3CA 3RIUA 2N2NA 3LK42 2BG9A 2K3WA 2LM2A 3T1YT 1G73A 2X66A 4YTMA 2KMFA 1VOMA 2E9XB 3N9OA 4IL9A 5ABEA 4Q25A 4UV8B 4CXWA 4PJMA 1HNZT 2H3RA 3ZN1B 3AB3B 1Y64B 3T8OA 1YXRA 5HWXA 3M3ZB 4C90A 2VURA 4YHHT 5IWAT 3E08A 3N9LA 2KINB 3RPUA 2WBLA 3RF1A 5F3JA 4PK4A 1NENA 4DNDA 4CN4A 3C4XA 3OBVE 1XMOT 2CEAA 4TWHA 2PBIA 4H63V 3TLSA 2BDEA 2BBHA 1UX4A 5HEGA 4LF6T 3RH3A 4I50E 3UUBA 3S4UA 2YK0A 3ANWA 3EHZA 3IEEA 5LB7B 3E22E 4NXNT 2UXCT 1OEDE 5EK2A 3KBUA 5LMNT 1KNZA 2N1GA 3E0ZA 4DV5T 1JNZA 3UUMA 4WBNE 3ZYKA 2ZLYA 3AEFA 5CA0E 3FB2A 3AEAA 4ILBA 4XBFB 3I0QA 5LMUT 1QUUA 4JI5T 1FMVA 1GQEA 4TNVA 3PUVF 4B3ST 4U31A 4I4TE 5FXVA 3UU5A 2H7OA 5FXXA 2WZHA 4TNWA 2J1DG 3Q5EA 4UXNB 3PUYF 3UU8A 1D1BA 4JUYA 2PJQA 2KLQA 3RLFF 4JI8T 1S35A 2HHHT 5LJNA 5KX5E 4NUVA 5HCMA 1Y01A 2A3DA 2X9WA 3CVRA 2DL1A 3L8RA 3RKGA 3CMLA 1KNRA 1WYCA 5HWYA 3VR8A 1OEDC 4WYVA 3D0TA 5AQUB 3ZT7A 5DJQC 2UXBT 2IW5B 5H6QB 5HXCA 5DABA 3ZT5A 4OX9T 5IYZE 3GWHA 3LSVA 4P1NA 1UURA 1XNQT 5F5WA 3AA1B 5AQSB 5FXWA 5AQVB 4A5XA 1VRBA 2VVNA 3T1HT 4HFIA 4YSYA 1YQ4A 4KBMB 3ZJ2A 2DI4A 1BR2A 2LHNA 3ZYLA 3JADA 4GIWA 4KI0F 4ADZA 4FI5A 3TLUA 2BZBA 2Y6XA 1S94A 4TWFA 4ERRA 1FIOA 3A5XA 4UVBB 4BAYB 1YW0A 2K5BB 5FXZA 3PUWF 2XSBA 4YXDA 2BS4A 3X1DA 4AISA 5HEHA 2VKJA 2WU5A 2IDOB 2DWGA 1XZYA 1IJ5A 2QVAA 1HG2A 3JAFA 3KV5A 4PJNA 5AQRB 4QWNB 3M65A 5FNVE 2IC6A 3PURA 5JDLA 3N9NA 5ABGA 4HN9A 1ZOYA 2CWYA 1ZP0A 3H3AA 3G06A 4PFOA 5C8YE 3GN5A 1X79A 4U72A 4IHJE 5HEUA 2CHOA 3UU4A 4LFCT 4TN7B 2CXDA 4QX7B 4JI1T 5JREA 3UU6A 4GKKT 4EIWA 3RI5A 2XQYA 3AE3A 4H9PC 5LG3A 5CFBA 2K24A 4NIQA 5JR9A 2D5UA 4PFPA 3ZT6A 5L3FB 4EYYR 4AQGA 1IBLT 3AEDA 3IF8B 2VQET 4QHOA 2J4GA 4A97A 2WMNA 4J2CA 4P0AA 3HKEE 4U7IA 2KNDA 2XQ7A 4YJ3E 1XDOA 3C64A 1CUNA 2OV9A 1FEWA 5LYJE 3ETUA 3VU7H 5EK3A 3FBZA 1QSDA 2X68A 3OYZA 1MMNA 2UUBT 2MPKA 4DUYT 3CIRA 3SWHA 1KEYA 2SPCA 3U3IA 3CQGB 3P4QA 1W9RA 4BA9A 5AQIB 2W62A 1LKXA 2VB6A 5J2TE 4YLHA 3MACA 3DJBA 2C5IT 3F57A 4HGAA 2YINA 2EHOA 4TZ4C 4UF0A 4MALA 4I0UA 3CX8B 2E5LT 3P8CD 2Y48B 4Z91A 4ZI3D 3PUXF 4U7YA 3LDQB 3F31A 4PK5A 1OXZA 2QRXA 2X67A 2ES0A 3LFMA 2XPKA 5AQQB 2X0YA 4COFA 2VQFT 2LOPA 2K9AA 4OFZA 5TAOA 4CI2B 3CX6B 1MIWA 1WR0A 3KV6A 4HWHA 3LG7A 2X0LB 4EB6E 2PTFA 3IBPA 3ZCIA 3ESLA 5ETWA 4H9RC 2J62A 3UQ4A 4UR9A 4X20E 2W63A 4O2BE 3PU3A 4U2ZA 1VCSA 1YQ3A 3EABA 1LRZA 3HKCE 4QXBB 1XMQT 2JJ9A 3PV0F 4AKIA 3PJAJ 5AQMB 3CX7B 4FJOA 4ZI7E 4A98A 4LMKA 4K0KT 3ZC1A 2VKDA 3WI3A 4PNIA 1XDPA 5LXTE 2WDQA 2DNXA 4IE4A 5JDQA 4BJNA 4BJMA 4H9QC 2XJ7A 3PUAA 2W2UA 2WSSV 5BMVE 4ANJA 1UUSA 4AQYT 4MLKA 1E7PA 1HX8A 1SUMB 2JQ9A 2IHR1 1YKEB 5JDMA 4KHZF 2WB5A 2EHOD 1L0VA 2JQQA 3AEEA 5CJ5A 2VVSA 3L09A 1DU2A 4LMJA 3KBTA 4DR2T 2C5KT 4ZZCA 2LSYA 2XTLA 4DR6T 1QLBA 2ZMAA 2XHEB 2PG8A 3F2EA 5FL1A 2MTQA 3LBXA 2A9UA 4KMCA 5LBMA 3SFDA 2VL0A 5KDMC 3RIAA 1MIYA 2AXDS 4B3MT 3BK9A 2D0UA 1KFYA 3SS1A 4X5TA 2YN6A 5AQJB 4WZXA 2FUPA 2CCQA 4L0RA 5DQVA 4JI2T 1LVFA 2HH7A 3AE1A 3N9PA 2FJAA 4HKAA 4DV0T 4B6XA 4IGUA 3H37A 3RC3A 3AE5A 1J5WA 3N9QA 4F6RC 3UT5E 4WBOA 2H89A 2J47A 5J2UE 3RIUC 4CQIA 4GKJT 4HWDA 3N2KE 3I9WA 2BG9C 1B7TA 4Z8XA 1NEKA 4EZ4A 4ZI2D 3R6NA 5HXEA 5HYAA 3JCFA 4QH4A 4IDZA 2M6BA 5EK4A 2M67A 3I9YA 3KVBA 4KHPT 3I1AA 2UUAT 2I59A 4X65T 2XM2A 3RRWA 4E7SA 1MMAA 4IE6A 3Q9DA 3ANWB 4HFHA 1CHUA 5HEOA 3VRBA 5JRCB 1J1JA 2X0HA 2Y8DA 1ZEEA 2UUCT 1U5PA 2RP4A 2Q9QB 2BKOA 2XQ6A 4EEDA 3N2OA 3ZEFB 3AE7A 3U78A 4N78D 4ZS2A 3ZJ1A 4UV9B 2W61A 4DV1T 4HFDA 3BQIA 2YDQA 3FZLB 4L5GA 2X9YA 3KV9A 3N2GE 1OEDB 5FY7A 1T7SA 2YEVC 3K3OA 5LBQB 4AQFA 4JV5T 4IE7A 4X1YE 4JI3T 2BBJA 2IUBA 2IC9A 2E9XD 3BQLA 1WYBA 4I55E 3NBXX 2WDRA 3UU3A 5CB4E 5HXHA 3K3NA 4DMVA 5C3JA 4YY3T 1IZNB 2X9HA 4IDOA 1SE7A 1WFDA 1HNWT 2VK9A 3P4PA 4H9OC 1YKHB 2FJEA 5J0ZA 3VKGA 5FVKA 4KX6A 5LOVE 1YD8G 3LK2B 2JRKA 3AA7B 2KWHA 5JDFA 1UX5A 2V7IA 5JTGA 5HEJA 4DMWA 1HR0T 3FZHB 1N36T 4KUMB 1H7CA 2V6XA 4EEBA 4ZS3A 1BR0A 2YU2A 2KWIB 2WCAA 2LRKA 5GONE 3QUJA 2CLYB 3EDVA 2VKHA 2R6GF 3Q5XA 2D0TA 4CXXA 2L8KA 3AVSA 5KXJA 4TUYE 3GA8A 5LCYA 3KINB 5J1GA 2V7KA 3MXZA 3W15B 4QH5A 5IUXA 2LLYA 4CZZB 2ZM6T 4LFAT 4X1KE 4ASKA 2C0SA 3PTRB 1IBMT 2Q9QD 2YOEA 3K1SA 5HCJA 1IAPA 4O2AE 3A7MA 4DR1T 1M62A 4DR5T 3NZQA 1HX1B 1MNDA 4JI0T 2WP9A 3NRYA 2ACZA 5ABHA 2OA5A 4CXYA 1IJ6A 2G0UA 4DV2T 3ZCJA 4NXMT 2E5VA 4JI7T 4LFBT 3P4SA 5E0OA 5LA6E 5LG4A 5EZYE 5L3BB 5LP6E 3AEBA 2YDRA 5HXRA 4XAXB 5M4YA 2LSKA 3AVRA 2XAHB 3C4WA 2V8SV 4LMLA 5LHHB 2WY2A 4GYRA 3QC9A 2CXFA 4QXHB 2NWBA 1T72A 1KF6A 2BKNA 4HFCA 5LGNB 5FMNA 3QB5A 3NKZA 4ZI3C 4ZOLE 2W00A 2MOZA 2XQAA 5L3EB 5AQFB 3PDYA 4PAGA 5FY0A 4C91A 3JC6D 3DTOA 3B5MA 3AE9A 3AA6B 4TV9E 1IBKT 2WWVA 3UULA 1N33T 4MFRA 5JR9C 2W66A 4L9IA 4JI4T 5AQGB 3ONJA 4AKRB 3QB5K 4CN6A 2IAKA 5L47A 2CHNA 3L39A 4DV6T 2VWAA 4EXTA 2I6HA 2BS3A 3C51A 2E8IA 4X1IE 2WQYA 1D0YA 3HA4A 3TLTA 1T8BA 4UVCB 4XZCA 3TKLB 3P4RA 4LF5T 3TLVA 2IIUA 3AXJA 4UF0B 2CBIA 2V1DB 3RQUA 4AKGA 4HFBA 3FHNA 2CM0A 4ILAA 4UEMA 2ODVA 2KXPB 1N32T 3CPZA 2BS2A 3KV4A 2XQ3A 3Q5DA 4CI3B 1HCIA 4DBRA 3OJAA 2LHRA 2N9DA 2EHOC 2RPAA 3SOLA 5AQHB 2KZ7B 1JNRA 2CWOA 2AE9A 3AE8A 2XSAA 4ISTA 4AIUA 2XY8B 4DVDA 3J7Yq 2NTYA 3EVYA 3V5UA 2DCFA 3RRCA 3RYHE 5ABFB 4LF7T 3MKDA 2YU1A 3SFEA 3ZMZB 2XQ8A 3CQCB 2WDVA 2ZM8A 4GK5E 5DQWA 2BVLA 3ZYMA 1G8XA 4PW8A 2LT3A 1AJ3A 4ISSA 4IT4A 3RYFE 2KSRA 4YTPA 2F4VT 2WMOA 3PUGA 4EYUA 3RQWA 3TLWA 3BQKA 4X62T 2FBWA 1US7B 4ZI2C 3ONXA 1SA0E 1HG5A 4G2AA 3PE0A 3WAKA 4IE5A 4EV6A 3MA9A 3UUXB 4DO0A 3VKHA 3P7IA 4MBQA 2NW7A 1UGOA 5A1LA 1VCTA 1J5ET 5JVDE 2JQKA 5FKYA 1Z0PA 3ZMUB 2IMLA 3Q5WA 4HWCA 1WR6A 2V6YB 3CWZB 3RC8A 1SHZC 5CGMA
chains in the Genus database with same CATH topology
1UK5A 5AQHB 5AQRB 5AQGB 5AQIB 5AQOB 1UGOA 3M3ZB 3FZKB 1M62A 5AQKB 5AQMB 5AQLB 5AQUB 3A8YC 3FZFB 1HX1B 4HWDA 5AQQB 5AQNB 1I6ZA 3FZLB 4HWIB 5AQJB 2D9DA 4HWFA 5AQFB 1M7KA 4HWCA 3FZMB 5AQPB 3LDQB 1T7SA 5AQSB 3FZHB 5AQTB 5AQVB 4HWHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UK5 A;  5AQH B;  5AQR B;  5AQG B;  5AQI B;  5AQO B;  1UGO A;  3M3Z B;  3FZK B;  1M62 A;  5AQK B;  5AQM B;  5AQL B;  5AQU B;  3A8Y C;  3FZF B;  1HX1 B;  4HWD A;  5AQQ B;  5AQN B;  1I6Z A;  3FZL B;  4HWI B;  5AQJ B;  2D9D A;  4HWF A;  5AQF B;  1M7K A;  4HWC A;  3FZM B;  5AQP B;  3LDQ B;  1T7S A;  5AQS B;  3FZH B;  5AQT B;  5AQV B;  4HWH A; 
#chains in the Genus database with same CATH topology
 3ZMT B;  4YT0 A;  2V26 A;  5AQK B;  2BG9 B;  2K48 A;  4LF4 T;  4IL4 A;  2X51 A;  4MHC A;  3C98 B;  4WW0 A;  2LRL A;  2E9X A;  3QK6 A;  4OYJ A;  3HI2 A;  3AE2 A;  2B76 A;  4HE8 A;  1MMG A;  2XUE A;  4EZH A;  4JI6 T;  1D0Z A;  1XWM A;  4UIG A;  1R8I A;  5L4H A;  2LJL A;  2YKS A;  5CA1 E;  2CBJ A;  2ODU A;  2V5C A;  4DV4 T;  5FP3 A;  4G63 A;  1I6Z A;  3HKB E;  3OTO T;  1HS7 A;  2WS3 A;  2V5D A;  4K0U A;  2V7M A;  3PJA A;  4EGW A;  2LSJ A;  4PJL A;  4DR4 T;  3AAE B;  3AEG A;  2WM9 A;  2E9X C;  2DHR A;  3UUN A;  3I0O A;  3LK3 B;  3K3Q C;  4H9S E;  1EZ3 A;  2W67 A;  4HFE A;  2WWU A;  5KMG P;  2LSI A;  5JDH A;  1D0X A;  1XNR T;  2XQ9 A;  2MYS A;  2A2F X;  4TV8 E;  2WU2 A;  4NUU A;  2FJD A;  3P50 A;  1T98 A;  3AAA B;  2DLR A;  3O1I A;  3OPC A;  5JQG E;  3R84 B;  3EAM A;  3ABV A;  4DR7 T;  5JRC A;  4P0B A;  5H6R B;  2PFV A;  2QGS A;  2UXX B;  3N9M A;  2BVM A;  3UFE A;  3C50 A;  5L3C B;  3P4W A;  3PUS A;  2Q9Q A;  2X9X A;  3K8P C;  1HFA A;  2JPF A;  4IDP A;  1OWA A;  5JDG A;  2VKO A;  2V7J A;  1HNX T;  3KVA A;  5AQP B;  3HL6 A;  4DID B;  3AE4 A;  2NW9 A;  4DR3 T;  1OED A;  5LNK A;  1UCU A;  2W0G A;  2Z6E A;  4ZHQ E;  5L2L A;  4O4H E;  4O4L E;  5L3G B;  3O9X A;  2HN1 A;  2XAJ B;  2Q9Q C;  2GK9 A;  1U4Q A;  5JDN A;  2H7V C;  2C5J A;  3OYX A;  3ZSS A;  3NVO A;  2QA7 A;  3ZMS B;  2UU9 T;  2LKG A;  4AQF C;  3N5L A;  4ZEY A;  4TWD A;  4V1A v;  1NAF A;  1MMD A;  3GMI A;  4QH1 A;  2UXN B;  1N34 T;  4IDQ A;  2BKP A;  5BR8 T;  1ZV4 X;  4HWF A;  4HEA A;  3H3M A;  4B3T T;  4QKN A;  2UXD T;  3Q2M A;  4JBW F;  5IHY A;  1KK7 A;  4TX5 A;  5C2T A;  1HTJ F;  3NRX A;  1ZKE A;  2NP9 A;  2NTX A;  2QYW A;  3RYI E;  3KFW X;  3AE6 A;  4UEL A;  4H63 H;  2NR4 A;  2LEH A;  5LGU B;  4DUZ T;  4WNK A;  1WLX A;  5JH7 E;  3JC6 C;  4ILU A;  1I94 T;  1E1H B;  2M6I A;  1WRD A;  3RYC E;  2XAS B;  2ZM0 A;  3ZST A;  4DV7 T;  2CLY C;  4HTE A;  3VRA A;  2XQ4 A;  4IE0 A;  4P09 A;  3PUZ F;  3PUQ A;  4E7Z A;  2CA5 A;  3MJX A;  2KT9 A;  4M1P A;  4NPP A;  3J9X 1;  4UVA B;  4CN1 A;  3FBL A;  3GN5 B;  4AKL A;  3WAJ A;  1D1C A;  4IIJ E;  2D2S A;  4U33 A;  4EAH A;  2XM1 A;  2FJB A;  1HF8 A;  3UTK A;  2CMR A;  3UFG A;  3CKD A;  4KP3 C;  5HAX A;  2MBG A;  5AQN B;  5FVL A;  2YDS A;  4HFV A;  5JR9 B;  3O4X E;  1E2A A;  3L3P A;  3KDS E;  3OKQ A;  3FZM B;  4AKH A;  2LOS A;  4OK0 A;  2JIW A;  4OHF A;  4IDN A;  3ETV A;  3FZF B;  1ZHC A;  3ZMV B;  2I0M A;  2JMH A;  3CQX C;  4I43 B;  4OYK A;  3NZP A;  4EOZ B;  1LVK A;  3DP7 A;  2XZE A;  2RA1 A;  2CXL A;  4QX8 B;  1NWM X;  5L4E A;  3MZK B;  2WAU A;  3FXE B;  4JEU B;  4PJJ A;  4HWI B;  3PU8 A;  1MIV A;  3B13 A;  3RKO A;  2XAQ B;  4B3R T;  3RX6 A;  4F8H A;  1WCR A;  3C4Z A;  3AEC A;  4DV3 T;  1UK5 A;  2HPL A;  2VL8 A;  4GOU A;  4AXP A;  2B1E A;  3QOF A;  3B57 A;  4O4J E;  3RIF A;  4O8S A;  2NW8 A;  4YTN A;  3ZLI A;  3CK6 A;  2EHO B;  4LF9 T;  2HN2 A;  2LE8 A;  1MNE A;  1KNP A;  3LJC A;  3EDU A;  5AFU L;  5LHI B;  3AXJ B;  1FJG T;  3FXD B;  3IHR A;  1W0A A;  2LSG A;  5ADX L;  5FL0 A;  4U2Y A;  3O1J A;  5LGT B;  3RGL A;  2DWK A;  3MK7 C;  2CRB A;  4YFS A;  4LF8 T;  2V7L A;  2W4X A;  4GYS A;  3A8Y C;  1BR1 A;  3EUH A;  4U74 A;  3ZN0 B;  2VAS A;  4IRE A;  2HPJ A;  4Z90 A;  2CE7 A;  2D9D A;  3O1H A;  2L9Q A;  3VR9 A;  2XAF B;  1M7K A;  1O3X A;  2WZI A;  3HR0 A;  2ACX A;  2JMK A;  4DBQ A;  2OLT A;  4YSX A;  4ZZB A;  3ONL C;  2JQH A;  3VHL A;  4AI6 A;  3AAI A;  4GK0 E;  5ABF A;  4X66 T;  4CI1 B;  3AA0 B;  2NOX A;  4YJ2 E;  3SRZ A;  4ILC A;  2H88 A;  5LJM A;  3QNU A;  2MAW A;  3RHW A;  1FMW A;  2CPT A;  3EI0 A;  2LKH A;  4ZXL A;  4JLE A;  5AQO B;  1D1A A;  5FYM A;  2XQ5 A;  4JEH B;  5HXS A;  2A72 A;  2ZM2 A;  4X64 T;  1V9D A;  1Z8U A;  3JAE A;  3NWI A;  2XAG B;  4H9N C;  5AQT B;  1BR4 A;  1X9B A;  3UQ7 A;  5L3D B;  3ZPO A;  3FZK B;  4O4I E;  5FY1 A;  2BG9 E;  2L3L A;  4JYA T;  2P9B A;  3IA3 A;  1W09 A;  3LBX B;  5LHG B;  3V5S A;  2LM9 A;  3ZKR A;  4YHJ A;  3OVU A;  4YSZ A;  4QXC B;  2E2A A;  3HKD E;  1W0B A;  5AQL B;  4PK6 A;  4A56 A;  5F8P A;  2V6Y A;  3ZC0 A;  4U3C A;  3RIU A;  2N2N A;  3LK4 2;  2BG9 A;  2K3W A;  2LM2 A;  3T1Y T;  1G73 A;  2X66 A;  4YTM A;  2KMF A;  1VOM A;  2E9X B;  3N9O A;  4IL9 A;  5ABE A;  4Q25 A;  4UV8 B;  4CXW A;  4PJM A;  1HNZ T;  2H3R A;  3ZN1 B;  3AB3 B;  1Y64 B;  3T8O A;  1YXR A;  5HWX A;  3M3Z B;  4C90 A;  2VUR A;  4YHH T;  5IWA T;  3E08 A;  3N9L A;  2KIN B;  3RPU A;  2WBL A;  3RF1 A;  5F3J A;  4PK4 A;  1NEN A;  4DND A;  4CN4 A;  3C4X A;  3OBV E;  1XMO T;  2CEA A;  4TWH A;  2PBI A;  4H63 V;  3TLS A;  2BDE A;  2BBH A;  1UX4 A;  5HEG A;  4LF6 T;  3RH3 A;  4I50 E;  3UUB A;  3S4U A;  2YK0 A;  3ANW A;  3EHZ A;  3IEE A;  5LB7 B;  3E22 E;  4NXN T;  2UXC T;  1OED E;  5EK2 A;  3KBU A;  5LMN T;  1KNZ A;  2N1G A;  3E0Z A;  4DV5 T;  1JNZ A;  3UUM A;  4WBN E;  3ZYK A;  2ZLY A;  3AEF A;  5CA0 E;  3FB2 A;  3AEA A;  4ILB A;  4XBF B;  3I0Q A;  5LMU T;  1QUU A;  4JI5 T;  1FMV A;  1GQE A;  4TNV A;  3PUV F;  4B3S T;  4U31 A;  4I4T E;  5FXV A;  3UU5 A;  2H7O A;  5FXX A;  2WZH A;  4TNW A;  2J1D G;  3Q5E A;  4UXN B;  3PUY F;  3UU8 A;  1D1B A;  4JUY A;  2PJQ A;  2KLQ A;  3RLF F;  4JI8 T;  1S35 A;  2HHH T;  5LJN A;  5KX5 E;  4NUV A;  5HCM A;  1Y01 A;  2A3D A;  2X9W A;  3CVR A;  2DL1 A;  3L8R A;  3RKG A;  3CML A;  1KNR A;  1WYC A;  5HWY A;  3VR8 A;  1OED C;  4WYV A;  3D0T A;  5AQU B;  3ZT7 A;  5DJQ C;  2UXB T;  2IW5 B;  5H6Q B;  5HXC A;  5DAB A;  3ZT5 A;  4OX9 T;  5IYZ E;  3GWH A;  3LSV A;  4P1N A;  1UUR A;  1XNQ T;  5F5W A;  3AA1 B;  5AQS B;  5FXW A;  5AQV B;  4A5X A;  1VRB A;  2VVN A;  3T1H T;  4HFI A;  4YSY A;  1YQ4 A;  4KBM B;  3ZJ2 A;  2DI4 A;  1BR2 A;  2LHN A;  3ZYL A;  3JAD A;  4GIW A;  4KI0 F;  4ADZ A;  4FI5 A;  3TLU A;  2BZB A;  2Y6X A;  1S94 A;  4TWF A;  4ERR A;  1FIO A;  3A5X A;  4UVB B;  4BAY B;  1YW0 A;  2K5B B;  5FXZ A;  3PUW F;  2XSB A;  4YXD A;  2BS4 A;  3X1D A;  4AIS A;  5HEH A;  2VKJ A;  2WU5 A;  2IDO B;  2DWG A;  1XZY A;  1IJ5 A;  2QVA A;  1HG2 A;  3JAF A;  3KV5 A;  4PJN A;  5AQR B;  4QWN B;  3M65 A;  5FNV E;  2IC6 A;  3PUR A;  5JDL A;  3N9N A;  5ABG A;  4HN9 A;  1ZOY A;  2CWY A;  1ZP0 A;  3H3A A;  3G06 A;  4PFO A;  5C8Y E;  3GN5 A;  1X79 A;  4U72 A;  4IHJ E;  5HEU A;  2CHO A;  3UU4 A;  4LFC T;  4TN7 B;  2CXD A;  4QX7 B;  4JI1 T;  5JRE A;  3UU6 A;  4GKK T;  4EIW A;  3RI5 A;  2XQY A;  3AE3 A;  4H9P C;  5LG3 A;  5CFB A;  2K24 A;  4NIQ A;  5JR9 A;  2D5U A;  4PFP A;  3ZT6 A;  5L3F B;  4EYY R;  4AQG A;  1IBL T;  3AED A;  3IF8 B;  2VQE T;  4QHO A;  2J4G A;  4A97 A;  2WMN A;  4J2C A;  4P0A A;  3HKE E;  4U7I A;  2KND A;  2XQ7 A;  4YJ3 E;  1XDO A;  3C64 A;  1CUN A;  2OV9 A;  1FEW A;  5LYJ E;  3ETU A;  3VU7 H;  5EK3 A;  3FBZ A;  1QSD A;  2X68 A;  3OYZ A;  1MMN A;  2UUB T;  2MPK A;  4DUY T;  3CIR A;  3SWH A;  1KEY A;  2SPC A;  3U3I A;  3CQG B;  3P4Q A;  1W9R A;  4BA9 A;  5AQI B;  2W62 A;  1LKX A;  2VB6 A;  5J2T E;  4YLH A;  3MAC A;  3DJB A;  2C5I T;  3F57 A;  4HGA A;  2YIN A;  2EHO A;  4TZ4 C;  4UF0 A;  4MAL A;  4I0U A;  3CX8 B;  2E5L T;  3P8C D;  2Y48 B;  4Z91 A;  4ZI3 D;  3PUX F;  4U7Y A;  3LDQ B;  3F31 A;  4PK5 A;  1OXZ A;  2QRX A;  2X67 A;  2ES0 A;  3LFM A;  2XPK A;  5AQQ B;  2X0Y A;  4COF A;  2VQF T;  2LOP A;  2K9A A;  4OFZ A;  5TAO A;  4CI2 B;  3CX6 B;  1MIW A;  1WR0 A;  3KV6 A;  4HWH A;  3LG7 A;  2X0L B;  4EB6 E;  2PTF A;  3IBP A;  3ZCI A;  3ESL A;  5ETW A;  4H9R C;  2J62 A;  3UQ4 A;  4UR9 A;  4X20 E;  2W63 A;  4O2B E;  3PU3 A;  4U2Z A;  1VCS A;  1YQ3 A;  3EAB A;  1LRZ A;  3HKC E;  4QXB B;  1XMQ T;  2JJ9 A;  3PV0 F;  4AKI A;  3PJA J;  5AQM B;  3CX7 B;  4FJO A;  4ZI7 E;  4A98 A;  4LMK A;  4K0K T;  3ZC1 A;  2VKD A;  3WI3 A;  4PNI A;  1XDP A;  5LXT E;  2WDQ A;  2DNX A;  4IE4 A;  5JDQ A;  4BJN A;  4BJM A;  4H9Q C;  2XJ7 A;  3PUA A;  2W2U A;  2WSS V;  5BMV E;  4ANJ A;  1UUS A;  4AQY T;  4MLK A;  1E7P A;  1HX8 A;  1SUM B;  2JQ9 A;  2IHR 1;  1YKE B;  5JDM A;  4KHZ F;  2WB5 A;  2EHO D;  1L0V A;  2JQQ A;  3AEE A;  5CJ5 A;  2VVS A;  3L09 A;  1DU2 A;  4LMJ A;  3KBT A;  4DR2 T;  2C5K T;  4ZZC A;  2LSY A;  2XTL A;  4DR6 T;  1QLB A;  2ZMA A;  2XHE B;  2PG8 A;  3F2E A;  5FL1 A;  2MTQ A;  3LBX A;  2A9U A;  4KMC A;  5LBM A;  3SFD A;  2VL0 A;  5KDM C;  3RIA A;  1MIY A;  2AXD S;  4B3M T;  3BK9 A;  2D0U A;  1KFY A;  3SS1 A;  4X5T A;  2YN6 A;  5AQJ B;  4WZX A;  2FUP A;  2CCQ A;  4L0R A;  5DQV A;  4JI2 T;  1LVF A;  2HH7 A;  3AE1 A;  3N9P A;  2FJA A;  4HKA A;  4DV0 T;  4B6X A;  4IGU A;  3H37 A;  3RC3 A;  3AE5 A;  1J5W A;  3N9Q A;  4F6R C;  3UT5 E;  4WBO A;  2H89 A;  2J47 A;  5J2U E;  3RIU C;  4CQI A;  4GKJ T;  4HWD A;  3N2K E;  3I9W A;  2BG9 C;  1B7T A;  4Z8X A;  1NEK A;  4EZ4 A;  4ZI2 D;  3R6N A;  5HXE A;  5HYA A;  3JCF A;  4QH4 A;  4IDZ A;  2M6B A;  5EK4 A;  2M67 A;  3I9Y A;  3KVB A;  4KHP T;  3I1A A;  2UUA T;  2I59 A;  4X65 T;  2XM2 A;  3RRW A;  4E7S A;  1MMA A;  4IE6 A;  3Q9D A;  3ANW B;  4HFH A;  1CHU A;  5HEO A;  3VRB A;  5JRC B;  1J1J A;  2X0H A;  2Y8D A;  1ZEE A;  2UUC T;  1U5P A;  2RP4 A;  2Q9Q B;  2BKO A;  2XQ6 A;  4EED A;  3N2O A;  3ZEF B;  3AE7 A;  3U78 A;  4N78 D;  4ZS2 A;  3ZJ1 A;  4UV9 B;  2W61 A;  4DV1 T;  4HFD A;  3BQI A;  2YDQ A;  3FZL B;  4L5G A;  2X9Y A;  3KV9 A;  3N2G E;  1OED B;  5FY7 A;  1T7S A;  2YEV C;  3K3O A;  5LBQ B;  4AQF A;  4JV5 T;  4IE7 A;  4X1Y E;  4JI3 T;  2BBJ A;  2IUB A;  2IC9 A;  2E9X D;  3BQL A;  1WYB A;  4I55 E;  3NBX X;  2WDR A;  3UU3 A;  5CB4 E;  5HXH A;  3K3N A;  4DMV A;  5C3J A;  4YY3 T;  1IZN B;  2X9H A;  4IDO A;  1SE7 A;  1WFD A;  1HNW T;  2VK9 A;  3P4P A;  4H9O C;  1YKH B;  2FJE A;  5J0Z A;  3VKG A;  5FVK A;  4KX6 A;  5LOV E;  1YD8 G;  3LK2 B;  2JRK A;  3AA7 B;  2KWH A;  5JDF A;  1UX5 A;  2V7I A;  5JTG A;  5HEJ A;  4DMW A;  1HR0 T;  3FZH B;  1N36 T;  4KUM B;  1H7C A;  2V6X A;  4EEB A;  4ZS3 A;  1BR0 A;  2YU2 A;  2KWI B;  2WCA A;  2LRK A;  5GON E;  3QUJ A;  2CLY B;  3EDV A;  2VKH A;  2R6G F;  3Q5X A;  2D0T A;  4CXX A;  2L8K A;  3AVS A;  5KXJ A;  4TUY E;  3GA8 A;  5LCY A;  3KIN B;  5J1G A;  2V7K A;  3MXZ A;  3W15 B;  4QH5 A;  5IUX A;  2LLY A;  4CZZ B;  2ZM6 T;  4LFA T;  4X1K E;  4ASK A;  2C0S A;  3PTR B;  1IBM T;  2Q9Q D;  2YOE A;  3K1S A;  5HCJ A;  1IAP A;  4O2A E;  3A7M A;  4DR1 T;  1M62 A;  4DR5 T;  3NZQ A;  1HX1 B;  1MND A;  4JI0 T;  2WP9 A;  3NRY A;  2ACZ A;  5ABH A;  2OA5 A;  4CXY A;  1IJ6 A;  2G0U A;  4DV2 T;  3ZCJ A;  4NXM T;  2E5V A;  4JI7 T;  4LFB T;  3P4S A;  5E0O A;  5LA6 E;  5LG4 A;  5EZY E;  5L3B B;  5LP6 E;  3AEB A;  2YDR A;  5HXR A;  4XAX B;  5M4Y A;  2LSK A;  3AVR A;  2XAH B;  3C4W A;  2V8S V;  4LML A;  5LHH B;  2WY2 A;  4GYR A;  3QC9 A;  2CXF A;  4QXH B;  2NWB A;  1T72 A;  1KF6 A;  2BKN A;  4HFC A;  5LGN B;  5FMN A;  3QB5 A;  3NKZ A;  4ZI3 C;  4ZOL E;  2W00 A;  2MOZ A;  2XQA A;  5L3E B;  5AQF B;  3PDY A;  4PAG A;  5FY0 A;  4C91 A;  3JC6 D;  3DTO A;  3B5M A;  3AE9 A;  3AA6 B;  4TV9 E;  1IBK T;  2WWV A;  3UUL A;  1N33 T;  4MFR A;  5JR9 C;  2W66 A;  4L9I A;  4JI4 T;  5AQG B;  3ONJ A;  4AKR B;  3QB5 K;  4CN6 A;  2IAK A;  5L47 A;  2CHN A;  3L39 A;  4DV6 T;  2VWA A;  4EXT A;  2I6H A;  2BS3 A;  3C51 A;  2E8I A;  4X1I E;  2WQY A;  1D0Y A;  3HA4 A;  3TLT A;  1T8B A;  4UVC B;  4XZC A;  3TKL B;  3P4R A;  4LF5 T;  3TLV A;  2IIU A;  3AXJ A;  4UF0 B;  2CBI A;  2V1D B;  3RQU A;  4AKG A;  4HFB A;  3FHN A;  2CM0 A;  4ILA A;  4UEM A;  2ODV A;  2KXP B;  1N32 T;  3CPZ A;  2BS2 A;  3KV4 A;  2XQ3 A;  3Q5D A;  4CI3 B;  1HCI A;  4DBR A;  3OJA A;  2LHR A;  2N9D A;  2EHO C;  2RPA A;  3SOL A;  5AQH B;  2KZ7 B;  1JNR A;  2CWO A;  2AE9 A;  3AE8 A;  2XSA A;  4IST A;  4AIU A;  2XY8 B;  4DVD A;  3J7Y q;  2NTY A;  3EVY A;  3V5U A;  2DCF A;  3RRC A;  3RYH E;  5ABF B;  4LF7 T;  3MKD A;  2YU1 A;  3SFE A;  3ZMZ B;  2XQ8 A;  3CQC B;  2WDV A;  2ZM8 A;  4GK5 E;  5DQW A;  2BVL A;  3ZYM A;  1G8X A;  4PW8 A;  2LT3 A;  1AJ3 A;  4ISS A;  4IT4 A;  3RYF E;  2KSR A;  4YTP A;  2F4V T;  2WMO A;  3PUG A;  4EYU A;  3RQW A;  3TLW A;  3BQK A;  4X62 T;  2FBW A;  1US7 B;  4ZI2 C;  3ONX A;  1SA0 E;  1HG5 A;  4G2A A;  3PE0 A;  3WAK A;  4IE5 A;  4EV6 A;  3MA9 A;  3UUX B;  4DO0 A;  3VKH A;  3P7I A;  4MBQ A;  2NW7 A;  1UGO A;  5A1L A;  1VCT A;  1J5E T;  5JVD E;  2JQK A;  5FKY A;  1Z0P A;  3ZMU B;  2IML A;  3Q5W A;  4HWC A;  1WR6 A;  2V6Y B;  3CWZ B;  3RC8 A;  1SHZ C;  5CGM A; 
#chains in the Genus database with same CATH homology
 1UK5 A;  5AQH B;  5AQR B;  5AQG B;  5AQI B;  5AQO B;  1UGO A;  3M3Z B;  3FZK B;  1M62 A;  5AQK B;  5AQM B;  5AQL B;  5AQU B;  3A8Y C;  3FZF B;  1HX1 B;  4HWD A;  5AQQ B;  5AQN B;  1I6Z A;  3FZL B;  4HWI B;  5AQJ B;  2D9D A;  4HWF A;  5AQF B;  1M7K A;  4HWC A;  3FZM B;  5AQP B;  3LDQ B;  1T7S A;  5AQS B;  3FZH B;  5AQT B;  5AQV B;  4HWH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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