5AQMB

Fragment-based screening of hsp70 sheds light on the functional role of atp-binding site residues
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
112
structure length
112
Chain Sequence
GSNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
pubmed doi rcsb
molecule tags Chaperone
source organism Homo sapiens
molecule keywords HEAT SHOCK COGNATE 71 KDA PROTEIN
total genus 44
structure length 112
sequence length 112
chains with identical sequence D
ec nomenclature
pdb deposition date 2015-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02179 BAG BAG domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.58.120 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase; Chain G, domain 1 BAG domain 5aqmB00
1M7KA 3LDQB 5AQJB 5AQVB 5AQFB 5AQUB 3FZFB 5AQRB 5AQOB 3FZMB 1M62A 1UK5A 4HWFA 1T7SA 4HWDA 5AQLB 1I6ZA 5AQTB 3FZHB 3FZLB 5AQNB 5AQHB 1HX1B 2D9DA 5AQIB 4HWCA 5AQPB 1UGOA 5AQMB 3M3ZB 5AQGB 4HWHA 3A8YC 4HWIB 5AQSB 5AQKB 5AQQB 3FZKB
chains in the Genus database with same CATH superfamily
3AE6A 2NR4A 2D0UA 4ZI3C 1ZOYA 1W09A 1D1CA 2IAKA 1UUSA 2XAGB 3E22E 5ETWA 4A56A 3AVSA 3AEAA 5LOVE 2UXDT 2XZEA 4PFOA 5JR9B 3N9OA 4BJMA 4HFBA 4UV9B 3WI3A 2EHOC 2BS3A 2UXCT 4EEDA 4GOUA 5L3GB 2HPLA 1EZ3A 3GN5B 5LGTB 2E2AA 4DR2T 3AVRA 3LSVA 4PK6A 2A72A 3UQ4A 2YKSA 5L47A 5FY7A 3RIUC 4KHZF 2D5UA 2QGSA 4C91A 2BBHA 3W15B 2XUEA 3I9YA 3PUZF 2QYWA 3VKHA 4Q25A 5FKYA 3MZKB 2OLTA 1X79A 4LMKA 1FJGT 2B1EA 4GK0E 4X64T 2KLQA 1QSDA 1XMOT 1D0YA 4J2CA 4Z8XA 4TV9E 2Q9QB 3RH3A 4PJLA 1Y01A 4PK4A 1SHZC 3ZMUB 1OXZA 2L8KA 5HEJA 4FJOA 2HHHT 4JI4T 4DV4T 2BKOA 2ZMAA 3RYCE 2LOSA 2GK9A 4DO0A 2E5LT 3AA6B 4G63A 3TLTA 4AQFC 4UVBB 1V9DA 4IDOA 2WDVA 4IE4A 3GMIA 3KV4A 3JCFA 1NEKA 3BQKA 5TAOA 4AKIA 3Q9DA 1KEYA 2LSYA 3PUVF 1W0AA 5JREA 1HG5A 4ANJA 4M1PA 1SE7A 5C3JA 3P4WA 5AQGB 3GWHA 2H7OA 3H37A 3FZKB 2X9WA 5FXXA 5BMVE 5AQOB 4P0AA 3LG7A 3CK6A 3EABA 1IBMT 2N9DA 3N2OA 3O1JA 4KI0F 4LF7T 2ODVA 2LE8A 4XBFB 1N34T 1MIVA 5LG3A 4CN1A 3PUYF 2XQ5A 2Z6EA 3OBVE 3ONXA 1HNWT 3B57A 4ILBA 1WFDA 4KX6A 1N32T 3LK42 3VKGA 2HPJA 4OYKA 3VRBA 3OKQA 4UVAB 2XSBA 4OX9T 2IIUA 1YKEB 2LSJA 2LSIA 3AAAB 5HXEA 1HX1B 3RKOA 1ZKEA 2N2NA 1FMWA 4QXCB 2PBIA 2XQYA 5HWXA 4TNVA 2I0MA 5HEGA 1WYCA 4A5XA 2H89A 3F57A 1FMVA 2DWKA 3G06A 5L4HA 2V7MA 4COFA 1MMDA 2WAUA 3QUJA 3O1IA 4OK0A 3FZFB 2J1DG 3VR8A 4IREA 2LHRA 3NZPA 3OJAA 4DVDA 3R6NA 3ZEFB 4O4JE 2WMOA 1D1BA 3CMLA 1D0ZA 3B5MA 3N9NA 4TWDA 2VQET 2E9XC 4KHPT 2XPKA 5ABGA 5JTGA 2PJQA 1UCUA 3CQGB 2BG9B 4ILCA 5EZYE 2BKNA 3ZKRA 1W0BA 3CKDA 3EI0A 1E7PA 4IE6A 2FJEA 3N9MA 4WNKA 3ONJA 2YN6A 3Q5EA 4YTNA 1UX5A 2WCAA 4JI0T 4YSZA 1SA0E 5ABHA 1XZYA 4NIQA 4ZEYA 3PUWF 3UU3A 3A8YC 4JV5T 5LGUB 3K3NA 2OV9A 1MMAA 1DU2A 1M62A 1LRZA 3P4QA 4GYRA 4DBQA 2LRLA 1D1AA 2ZLYA 4OYJA 3NVOA 4IE5A 1XDOA 4EXTA 4QKNA 4DR5T 5L3DB 2WWVA 3I1AA 2AXDS 3RKGA 2XQ3A 5JR9C 4O8SA 5JDNA 4G2AA 2NOXA 5EK3A 4HTEA 4AQGA 3T1YT 1SUMB 5KMGP 4U33A 3ZJ2A 4PW8A 4ILAA 4CXXA 3Q5DA 2BVMA 4WBNE 4YJ2E 4O2AE 4YLHA 2W2UA 2FJAA 2WMNA 2Y48B 1QUUA 3UTKA 5FNVE 3HL6A 4O4LE 3KINB 4ZI3D 3KV6A 4PAGA 4PFPA 1BR1A 2V7IA 3C50A 2IC6A 3UUNA 4X65T 2BZBA 1S94A 2YU2A 3UQ7A 4DMWA 5LXTE 4PJJA 3CWZB 3LBXB 3RX6A 2J62A 2A9UA 2UXBT 3RPUA 3N2KE 3H3AA 3AXJB 1G8XA 4MHCA 2V7LA 5LBQB 1BR0A 2YEVC 3RI5A 5A1LA 2E5VA 4V1Av 4IT4A 2CHNA 1KNZA 3CX6B 2WB5A 3JC6C 2QRXA 3AE9A 5LGNB 4TN7B 4YTPA 3GA8A 2EHOA 4DV3T 2M6IA 3ANWA 3MKDA 5LJMA 2ES0A 3DJBA 2XQ9A 5L3CB 2LT3A 2W0GA 1KFYA 4X20E 2VKJA 3N9PA 4JEHB 4A98A 4HFHA 2WU2A 1YW0A 2LSKA 4B6XA 4KP3C 4DR4T 5J2TE 4AKRB 5ABFA 2JJ9A 3RF1A 3PE0A 3PUGA 4X62T 2W4XA 3NWIA 5AQLB 1R8IA 5L4EA 1XNRT 3C4WA 2LSGA 5GONE 5JDQA 4PNIA 4DV7T 4AXPA 4XAXB 5DABA 3HKBE 4P09A 3KV9A 2MBGA 2XASB 2V7JA 2DL1A 5FXZA 4GK5E 3SRZA 1UGOA 2LM9A 2WDRA 3ZPOA 3PTRB 4B3RT 1HCIA 2JQ9A 1UX4A 2UU9T 2LKHA 2CWYA 3OVUA 4NUVA 4DIDB 3AE7A 3NBXX 1T72A 4EZHA 5JDHA 5HAXA 2WQYA 4YT0A 3RYFE 2V5DA 4EAHA 2KWIB 5AQVB 4EGWA 2KINB 4IDZA 1G73A 3S4UA 2X51A 3ZLIA 4EIWA 1OEDA 3PURA 2P9BA 4HE8A 4NXMT 3EDUA 4HWCA 5LHHB 5IHYA 3RGLA 2C5IT 4U7YA 4JI3T 3TLWA 2M67A 2JPFA 4ISTA 2CBJA 3I9WA 2XM1A 3FBLA 5HXCA 4HWDA 3NZQA 2W63A 4ZZCA 4EEBA 4CZZB 3K8PC 4PJMA 5FXWA 4QX7B 3AAEB 5H6RB 5JRCB 3AE5A 2VASA 2QVAA 2KXPB 1CHUA 3L3PA 1KK7A 5AQHB 1OWAA 5IWAT 5JH7E 5J1GA 2BG9C 4KMCA 3RRCA 2X0HA 3PUQA 4LMLA 3T1HT 3VRAA 5FY0A 2CXFA 1NENA 5CJ5A 3FZHB 4PJNA 5AFUL 2UXXB 3C4XA 4HEAA 3EAMA 4H63H 2NTXA 3UUXB 1MIYA 4AI6A 5BR8T 3M65A 1UK5A 2E9XD 3NRYA 2Y8DA 2D9DA 3ZYMA 4NPPA 5AQMB 1WRDA 4IDNA 5F3JA 3HKDE 5F8PA 3FBZA 3R84B 3D0TA 3JAEA 2J47A 4U2YA 5FVKA 3AE1A 4CXWA 2E9XA 4A97A 2CLYB 3ABVA 2LOPA 2G0UA 3AE4A 3VHLA 1KNRA 1YXRA 3N9QA 2XQ6A 1ZV4X 4UF0A 3FXEB 4UIGA 3RC8A 4LF8T 5LMNT 2AE9A 2X9XA 3PU8A 4P0BA 4ZI2D 4IDQA 4YTMA 5ADXL 5HEOA 4LF9T 3JAFA 2XM2A 4U2ZA 4DMVA 2XQ8A 4O4HE 4JI5T 3T8OA 5DQVA 5HXRA 2JQQA 2HH7A 3ETVA 4KUMB 5EK2A 2XQ4A 2CEAA 5AQRB 1JNZA 4IL9A 4H9SE 5LMUT 5LP6E 2CA5A 2B76A 2J4GA 5JR9A 1HTJF 2WZIA 4JLEA 3AEFA 2LJLA 3PDYA 3P8CD 2V5CA 3HA4A 4ZXLA 3QB5A 2MPKA 2CWOA 2XAJB 3GN5A 2I59A 3KDSE 3ESLA 1FEWA 3CIRA 5E0OA 4IL4A 1CUNA 5FYMA 2XY8B 2IMLA 2Q9QD 5AQUB 4HGAA 5IUXA 3N2GE 2DI4A 4B3ST 4X1IE 4B3TT 2JRKA 3ZYKA 5CB4E 3MJXA 5CA1E 2KMFA 2W67A 2WM9A 3B13A 5AQJB 2C0SA 3MK7C 2Q9QA 2V1DB 2WS3A 2YU1A 2X9YA 4C90A 1I94T 3PUSA 4H9PC 3EVYA 4OFZA 3UU4A 4YSXA 5LNKA 3IEEA 2K3WA 2CBIA 3OPCA 2WBLA 3HI2A 5HXHA 3AAIA 3H3MA 2BS4A 1NWMX 2RP4A 4H9OC 1O3XA 4DR7T 5LG4A 1IZNB 4EOZB 3VR9A 4YXDA 2CHOA 4HN9A 4AISA 4TZ4C 2RPAA 3TKLB 2YOEA 4HFCA 4JI2T 3CVRA 4X1YE 4GKJT 2OA5A 2VWAA 3KBTA 2N1GA 2NWBA 5HCJA 3AE3A 2MAWA 2DWGA 3QK6A 4MALA 4JI1T 1HG2A 5FMNA 2NP9A 3AE8A 5C2TA 3PV0F 4Z90A 5LCYA 1VCTA 3O9XA 3UU5A 1MMGA 1OEDE 1E2AA 3UFEA 4I4TE 5J2UE 3ZMTB 3E08A 4UELA 5HWYA 1XDPA 4I43B 2EHOD 4EB6E 4LFBT 3FXDB 2XAQB 5JDGA 3K3QC 4I0UA 3L39A 1UURA 3K1SA 4QHOA 4QH5A 2ZM6T 4ZOLE 3RIFA 5KXJA 2UUAT 4ZHQE 3MA9A 1XMQT 2VL0A 3P50A 5HEHA 3QOFA 3UUMA 2FBWA 3LDQB 1XNQT 2CXLA 3EUHA 1HS7A 3CQXC 4N78D 4DR6T 1T8BA 5HXSA 4HFIA 2IDOB 3X1DA 1ZHCA 2ACXA 4U3CA 1JNRA 3LK3B 3SWHA 4E7ZA 3RIAA 3ZCJA 2YDRA 3RIUA 5DJQC 5C8YE 3PUXF 3EHZA 4JI7T 3NRXA 4CN6A 3TLUA 2JMHA 3ZT5A 2JQHA 2KWHA 3UT5E 1GQEA 4JI6T 4CI3B 2XAFB 4FI5A 2X68A 3ZSSA 4BJNA 2VQFT 4MBQA 5FVLA 2UXNB 2BDEA 5LHIB 4TX5A 5IYZE 2CLYC 2VK9A 3QB5K 1Z8UA 4YJ3E 4DR1T 4L0RA 4ILUA 2BG9A 4EYYR 4CN4A 2UUCT 4BA9A 1U4QA 4AKHA 1L0VA 2X0LB 3AA0B 3L8RA 4HWIB 4IIJE 1WLXA 3RRWA 3V5UA 3FB2A 2WWUA 1KF6A 1LVKA 1YQ4A 4AQFA 4JBWF 4MLKA 4WW0A 3FHNA 1HF8A 2VKOA 4Z91A 4GIWA 1MNDA 4O4IE 4ASKA 4CQIA 2V7KA 1M7KA 2WDQA 3HKCE 2R6GF 4YHJA 4YY3T 3SFEA 2X9HA 3KFWX 5LYJE 4LF5T 1VCSA 3JADA 3AA7B 1U5PA 3C64A 2VB6A 3WAJA 2ODUA 3VU7H 4DV5T 2ZM2A 2LRKA 3F2EA 3O4XE 4GKKT 3OYXA 2D2SA 4H9NC 3FZMB 3TLSA 3Q5XA 4DR3T 4IHJE 1MIWA 5CFBA 2NW8A 5FL0A 2YINA 2BBJA 1YKHB 4U31A 3P4RA 5L3EB 1J5ET 1LVFA 1HNZT 5F5WA 2JMKA 4HWFA 4DUYT 4JYAT 3LJCA 3P4SA 1VOMA 4ZI7E 2JQKA 3ZT6A 4TNWA 4MFRA 5AQKB 4LFCT 2MTQA 1H7CA 4YHHT 3NKZA 4OHFA 4NXNT 4X66T 4GYSA 2LLYA 3LBXA 5JDFA 3O1HA 4UXNB 1I6ZA 2V6YA 4LMJA 2L9QA 2CXDA 3AXJA 2IUBA 4ISSA 2CE7A 3LK2B 2ZM0A 3A5XA 1QLBA 5H6QB 4HFEA 5JQGE 3PJAJ 4F6RC 5CGMA 4L9IA 4IGUA 2IHR1 3LFMA 1ZEEA 5M4YA 2C5KT 4LF4T 3SS1A 4YSYA 2A2FX 5EK4A 3UULA 3MACA 1BR4A 2XSAA 1T98A 3J7Yq 2MYSA 4I50E 3UUBA 4AQYT 1N36T 3C51A 2YK0A 3UU8A 1B7TA 1IAPA 5AQPB 3ZT7A 4E7SA 1HFAA 1OEDC 3EDVA 4ADZA 2KZ7B 5FL1A 5KX5E 3ZN0B 2X0YA 2WZHA 5JVDE 4U7IA 2XTLA 1HNXT 2CPTA 2KNDA 3CQCB 2H3RA 3N5LA 4JUYA 5J0ZA 2I6HA 2VKDA 4UV8B 1IBKT 3P7IA 1X9BA 2K9AA 3Q5WA 2X67A 2KSRA 3PUAA 2VVSA 5L2LA 1YQ3A 2HN2A 2V26A 2CM0A 5JDMA 1N33T 4K0KT 4U74A 4HWHA 1J1JA 2V6XA 4IDPA 2UUBT 1Y64B 2JIWA 5LA6E 3ZC0A 3BK9A 2NW7A 2IC9A 5JDLA 1D0XA 5FP3A 2EHOB 3N9LA 5AQSB 3KV5A 3SFDA 1WYBA 1NAFA 3ANWB 1KNPA 4HFVA 4QX8B 2VKHA 3RYHE 2LKGA 4QH1A 5AQNB 4UR9A 3I0OA 2BS2A 2SPCA 2W61A 3C98B 4QWNB 2ZM8A 2K24A 1IBLT 2PFVA 5ABFB 4LFAT 3PJAA 1MMNA 4IE7A 1BR2A 3UU6A 1HX8A 1YD8G 4U72A 4B3MT 1Z0PA 1IJ5A 3JC6D 3OTOT 2PTFA 3RYIE 2MOZA 3U78A 1ZP0A 4JEUB 4XZCA 3AECA 2BVLA 3ETUA 4TWHA 2E8IA 5JRCA 4ZZBA 4ZS3A 3BQIA 2BKPA 3A7MA 3ZMVB 4LF6T 3AA1B 3KVBA 4DV2T 2FJBA 5LB7B 2A3DA 3ZSTA 4H9RC 2W00A 3P4PA 3F31A 2HN1A 2XAHB 2VURA 2F4VT 3HKEE 2PG8A 2WY2A 4UEMA 2XHEB 4CXYA 1HR0T 3UFGA 4CI2B 4WBOA 2DLRA 3AEEA 2L3LA 1VRBA 2LHNA 2CMRA 2YDSA 2BG9E 4TUYE 1E1HB 2K48A 3RHWA 2WP9A 5ABEA 4X5TA 3RQUA 3K3OA 4ZI2C 2H88A 4WYVA 1OEDB 4NUUA 2QA7A 3IHRA 4EYUA 1WCRA 2DCFA 4O2BE 3HR0A 1US7B 2VL8A 5DQWA 5AQFB 3ZC1A 4H63V 3WAKA 2LM2A 2VVNA 3RLFF 2W62A 4DNDA 1T7SA 4EZ4A 3SOLA 1FIOA 2WSSV 4YFSA 4DV0T 3CPZA 3QC9A 4F8HA 2IW5B 3DTOA 3C4ZA 5HYAA 3V5SA 5LBMA 2H7VC 4UVCB 2CRBA 3AB3B 2XJ7A 4H9QC 3CX8B 5AQTB 3TLVA 5FXVA 4ERRA 2KT9A 4HKAA 5AQIB 2NW9A 4CI1B 1WR0A 3ZN1B 3IA3A 5AQQB 1XWMA 3AEBA 2XQ7A 3AEGA 3PU3A 5KDMC 5FY1A 3ZMSB 3MXZA 2V6YB 2Y6XA 4P1NA 4QH4A 3FZLB 4AKGA 2Q9QC 3ONLC 4JI8T 4PK5A 3E0ZA 1W9RA 4DV6T 4WZXA 2CCQA 2DHRA 4DBRA 4TWFA 2DNXA 4QXHB 2NTYA 1S35A 1LKXA 2RA1A 3L09A 5LHGB 4EV6A 3DP7A 5CA0E 4TV8E 1WR6A 3M3ZB 3ZCIA 2ACZA 4KBMB 2WU5A 3IF8B 3AEDA 3U3IA 5L3BB 2K5BB 1IJ6A 2FJDA 2V8SV 4DUZT 2E9XB 4K0UA 4L5GA 4DV1T 3IBPA 5L3FB 4I55E 2C5JA 3ZMZB 2FUPA 3ZYLA 5LJNA 2XQAA 4X1KE 4QXBB 4UF0B 3J9X1 3BQLA 4ZS2A 2W66A 3QNUA 3KVAA 1MNEA 2D0TA 4AIUA 3CX7B 4AKLA 4IE0A 3OYZA 1J5WA 3I0QA 5HEUA 2M6BA 3RC3A 3RQWA 2X66A 4HFDA 3ZJ1A 3AE2A 3KBUA 3Q2MA 4BAYB 5HCMA 2LEHA 2YDQA 1AJ3A
chains in the Genus database with same CATH topology
1M7KA 3LDQB 5AQJB 5AQVB 5AQFB 5AQUB 3FZFB 5AQRB 5AQOB 3FZMB 1M62A 1UK5A 4HWFA 1T7SA 4HWDA 5AQLB 1I6ZA 5AQTB 3FZHB 3FZLB 5AQNB 5AQHB 1HX1B 2D9DA 5AQIB 4HWCA 5AQPB 1UGOA 5AQMB 3M3ZB 5AQGB 4HWHA 3A8YC 4HWIB 5AQSB 5AQKB 5AQQB 3FZKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M7K A;  3LDQ B;  5AQJ B;  5AQV B;  5AQF B;  5AQU B;  3FZF B;  5AQR B;  5AQO B;  3FZM B;  1M62 A;  1UK5 A;  4HWF A;  1T7S A;  4HWD A;  5AQL B;  1I6Z A;  5AQT B;  3FZH B;  3FZL B;  5AQN B;  5AQH B;  1HX1 B;  2D9D A;  5AQI B;  4HWC A;  5AQP B;  1UGO A;  5AQM B;  3M3Z B;  5AQG B;  4HWH A;  3A8Y C;  4HWI B;  5AQS B;  5AQK B;  5AQQ B;  3FZK B; 
#chains in the Genus database with same CATH topology
 3AE6 A;  2NR4 A;  2D0U A;  4ZI3 C;  1ZOY A;  1W09 A;  1D1C A;  2IAK A;  1UUS A;  2XAG B;  3E22 E;  5ETW A;  4A56 A;  3AVS A;  3AEA A;  5LOV E;  2UXD T;  2XZE A;  4PFO A;  5JR9 B;  3N9O A;  4BJM A;  4HFB A;  4UV9 B;  3WI3 A;  2EHO C;  2BS3 A;  2UXC T;  4EED A;  4GOU A;  5L3G B;  2HPL A;  1EZ3 A;  3GN5 B;  5LGT B;  2E2A A;  4DR2 T;  3AVR A;  3LSV A;  4PK6 A;  2A72 A;  3UQ4 A;  2YKS A;  5L47 A;  5FY7 A;  3RIU C;  4KHZ F;  2D5U A;  2QGS A;  4C91 A;  2BBH A;  3W15 B;  2XUE A;  3I9Y A;  3PUZ F;  2QYW A;  3VKH A;  4Q25 A;  5FKY A;  3MZK B;  2OLT A;  1X79 A;  4LMK A;  1FJG T;  2B1E A;  4GK0 E;  4X64 T;  2KLQ A;  1QSD A;  1XMO T;  1D0Y A;  4J2C A;  4Z8X A;  4TV9 E;  2Q9Q B;  3RH3 A;  4PJL A;  1Y01 A;  4PK4 A;  1SHZ C;  3ZMU B;  1OXZ A;  2L8K A;  5HEJ A;  4FJO A;  2HHH T;  4JI4 T;  4DV4 T;  2BKO A;  2ZMA A;  3RYC E;  2LOS A;  2GK9 A;  4DO0 A;  2E5L T;  3AA6 B;  4G63 A;  3TLT A;  4AQF C;  4UVB B;  1V9D A;  4IDO A;  2WDV A;  4IE4 A;  3GMI A;  3KV4 A;  3JCF A;  1NEK A;  3BQK A;  5TAO A;  4AKI A;  3Q9D A;  1KEY A;  2LSY A;  3PUV F;  1W0A A;  5JRE A;  1HG5 A;  4ANJ A;  4M1P A;  1SE7 A;  5C3J A;  3P4W A;  5AQG B;  3GWH A;  2H7O A;  3H37 A;  3FZK B;  2X9W A;  5FXX A;  5BMV E;  5AQO B;  4P0A A;  3LG7 A;  3CK6 A;  3EAB A;  1IBM T;  2N9D A;  3N2O A;  3O1J A;  4KI0 F;  4LF7 T;  2ODV A;  2LE8 A;  4XBF B;  1N34 T;  1MIV A;  5LG3 A;  4CN1 A;  3PUY F;  2XQ5 A;  2Z6E A;  3OBV E;  3ONX A;  1HNW T;  3B57 A;  4ILB A;  1WFD A;  4KX6 A;  1N32 T;  3LK4 2;  3VKG A;  2HPJ A;  4OYK A;  3VRB A;  3OKQ A;  4UVA B;  2XSB A;  4OX9 T;  2IIU A;  1YKE B;  2LSJ A;  2LSI A;  3AAA B;  5HXE A;  1HX1 B;  3RKO A;  1ZKE A;  2N2N A;  1FMW A;  4QXC B;  2PBI A;  2XQY A;  5HWX A;  4TNV A;  2I0M A;  5HEG A;  1WYC A;  4A5X A;  2H89 A;  3F57 A;  1FMV A;  2DWK A;  3G06 A;  5L4H A;  2V7M A;  4COF A;  1MMD A;  2WAU A;  3QUJ A;  3O1I A;  4OK0 A;  3FZF B;  2J1D G;  3VR8 A;  4IRE A;  2LHR A;  3NZP A;  3OJA A;  4DVD A;  3R6N A;  3ZEF B;  4O4J E;  2WMO A;  1D1B A;  3CML A;  1D0Z A;  3B5M A;  3N9N A;  4TWD A;  2VQE T;  2E9X C;  4KHP T;  2XPK A;  5ABG A;  5JTG A;  2PJQ A;  1UCU A;  3CQG B;  2BG9 B;  4ILC A;  5EZY E;  2BKN A;  3ZKR A;  1W0B A;  3CKD A;  3EI0 A;  1E7P A;  4IE6 A;  2FJE A;  3N9M A;  4WNK A;  3ONJ A;  2YN6 A;  3Q5E A;  4YTN A;  1UX5 A;  2WCA A;  4JI0 T;  4YSZ A;  1SA0 E;  5ABH A;  1XZY A;  4NIQ A;  4ZEY A;  3PUW F;  3UU3 A;  3A8Y C;  4JV5 T;  5LGU B;  3K3N A;  2OV9 A;  1MMA A;  1DU2 A;  1M62 A;  1LRZ A;  3P4Q A;  4GYR A;  4DBQ A;  2LRL A;  1D1A A;  2ZLY A;  4OYJ A;  3NVO A;  4IE5 A;  1XDO A;  4EXT A;  4QKN A;  4DR5 T;  5L3D B;  2WWV A;  3I1A A;  2AXD S;  3RKG A;  2XQ3 A;  5JR9 C;  4O8S A;  5JDN A;  4G2A A;  2NOX A;  5EK3 A;  4HTE A;  4AQG A;  3T1Y T;  1SUM B;  5KMG P;  4U33 A;  3ZJ2 A;  4PW8 A;  4ILA A;  4CXX A;  3Q5D A;  2BVM A;  4WBN E;  4YJ2 E;  4O2A E;  4YLH A;  2W2U A;  2FJA A;  2WMN A;  2Y48 B;  1QUU A;  3UTK A;  5FNV E;  3HL6 A;  4O4L E;  3KIN B;  4ZI3 D;  3KV6 A;  4PAG A;  4PFP A;  1BR1 A;  2V7I A;  3C50 A;  2IC6 A;  3UUN A;  4X65 T;  2BZB A;  1S94 A;  2YU2 A;  3UQ7 A;  4DMW A;  5LXT E;  4PJJ A;  3CWZ B;  3LBX B;  3RX6 A;  2J62 A;  2A9U A;  2UXB T;  3RPU A;  3N2K E;  3H3A A;  3AXJ B;  1G8X A;  4MHC A;  2V7L A;  5LBQ B;  1BR0 A;  2YEV C;  3RI5 A;  5A1L A;  2E5V A;  4V1A v;  4IT4 A;  2CHN A;  1KNZ A;  3CX6 B;  2WB5 A;  3JC6 C;  2QRX A;  3AE9 A;  5LGN B;  4TN7 B;  4YTP A;  3GA8 A;  2EHO A;  4DV3 T;  2M6I A;  3ANW A;  3MKD A;  5LJM A;  2ES0 A;  3DJB A;  2XQ9 A;  5L3C B;  2LT3 A;  2W0G A;  1KFY A;  4X20 E;  2VKJ A;  3N9P A;  4JEH B;  4A98 A;  4HFH A;  2WU2 A;  1YW0 A;  2LSK A;  4B6X A;  4KP3 C;  4DR4 T;  5J2T E;  4AKR B;  5ABF A;  2JJ9 A;  3RF1 A;  3PE0 A;  3PUG A;  4X62 T;  2W4X A;  3NWI A;  5AQL B;  1R8I A;  5L4E A;  1XNR T;  3C4W A;  2LSG A;  5GON E;  5JDQ A;  4PNI A;  4DV7 T;  4AXP A;  4XAX B;  5DAB A;  3HKB E;  4P09 A;  3KV9 A;  2MBG A;  2XAS B;  2V7J A;  2DL1 A;  5FXZ A;  4GK5 E;  3SRZ A;  1UGO A;  2LM9 A;  2WDR A;  3ZPO A;  3PTR B;  4B3R T;  1HCI A;  2JQ9 A;  1UX4 A;  2UU9 T;  2LKH A;  2CWY A;  3OVU A;  4NUV A;  4DID B;  3AE7 A;  3NBX X;  1T72 A;  4EZH A;  5JDH A;  5HAX A;  2WQY A;  4YT0 A;  3RYF E;  2V5D A;  4EAH A;  2KWI B;  5AQV B;  4EGW A;  2KIN B;  4IDZ A;  1G73 A;  3S4U A;  2X51 A;  3ZLI A;  4EIW A;  1OED A;  3PUR A;  2P9B A;  4HE8 A;  4NXM T;  3EDU A;  4HWC A;  5LHH B;  5IHY A;  3RGL A;  2C5I T;  4U7Y A;  4JI3 T;  3TLW A;  2M67 A;  2JPF A;  4IST A;  2CBJ A;  3I9W A;  2XM1 A;  3FBL A;  5HXC A;  4HWD A;  3NZQ A;  2W63 A;  4ZZC A;  4EEB A;  4CZZ B;  3K8P C;  4PJM A;  5FXW A;  4QX7 B;  3AAE B;  5H6R B;  5JRC B;  3AE5 A;  2VAS A;  2QVA A;  2KXP B;  1CHU A;  3L3P A;  1KK7 A;  5AQH B;  1OWA A;  5IWA T;  5JH7 E;  5J1G A;  2BG9 C;  4KMC A;  3RRC A;  2X0H A;  3PUQ A;  4LML A;  3T1H T;  3VRA A;  5FY0 A;  2CXF A;  1NEN A;  5CJ5 A;  3FZH B;  4PJN A;  5AFU L;  2UXX B;  3C4X A;  4HEA A;  3EAM A;  4H63 H;  2NTX A;  3UUX B;  1MIY A;  4AI6 A;  5BR8 T;  3M65 A;  1UK5 A;  2E9X D;  3NRY A;  2Y8D A;  2D9D A;  3ZYM A;  4NPP A;  5AQM B;  1WRD A;  4IDN A;  5F3J A;  3HKD E;  5F8P A;  3FBZ A;  3R84 B;  3D0T A;  3JAE A;  2J47 A;  4U2Y A;  5FVK A;  3AE1 A;  4CXW A;  2E9X A;  4A97 A;  2CLY B;  3ABV A;  2LOP A;  2G0U A;  3AE4 A;  3VHL A;  1KNR A;  1YXR A;  3N9Q A;  2XQ6 A;  1ZV4 X;  4UF0 A;  3FXE B;  4UIG A;  3RC8 A;  4LF8 T;  5LMN T;  2AE9 A;  2X9X A;  3PU8 A;  4P0B A;  4ZI2 D;  4IDQ A;  4YTM A;  5ADX L;  5HEO A;  4LF9 T;  3JAF A;  2XM2 A;  4U2Z A;  4DMV A;  2XQ8 A;  4O4H E;  4JI5 T;  3T8O A;  5DQV A;  5HXR A;  2JQQ A;  2HH7 A;  3ETV A;  4KUM B;  5EK2 A;  2XQ4 A;  2CEA A;  5AQR B;  1JNZ A;  4IL9 A;  4H9S E;  5LMU T;  5LP6 E;  2CA5 A;  2B76 A;  2J4G A;  5JR9 A;  1HTJ F;  2WZI A;  4JLE A;  3AEF A;  2LJL A;  3PDY A;  3P8C D;  2V5C A;  3HA4 A;  4ZXL A;  3QB5 A;  2MPK A;  2CWO A;  2XAJ B;  3GN5 A;  2I59 A;  3KDS E;  3ESL A;  1FEW A;  3CIR A;  5E0O A;  4IL4 A;  1CUN A;  5FYM A;  2XY8 B;  2IML A;  2Q9Q D;  5AQU B;  4HGA A;  5IUX A;  3N2G E;  2DI4 A;  4B3S T;  4X1I E;  4B3T T;  2JRK A;  3ZYK A;  5CB4 E;  3MJX A;  5CA1 E;  2KMF A;  2W67 A;  2WM9 A;  3B13 A;  5AQJ B;  2C0S A;  3MK7 C;  2Q9Q A;  2V1D B;  2WS3 A;  2YU1 A;  2X9Y A;  4C90 A;  1I94 T;  3PUS A;  4H9P C;  3EVY A;  4OFZ A;  3UU4 A;  4YSX A;  5LNK A;  3IEE A;  2K3W A;  2CBI A;  3OPC A;  2WBL A;  3HI2 A;  5HXH A;  3AAI A;  3H3M A;  2BS4 A;  1NWM X;  2RP4 A;  4H9O C;  1O3X A;  4DR7 T;  5LG4 A;  1IZN B;  4EOZ B;  3VR9 A;  4YXD A;  2CHO A;  4HN9 A;  4AIS A;  4TZ4 C;  2RPA A;  3TKL B;  2YOE A;  4HFC A;  4JI2 T;  3CVR A;  4X1Y E;  4GKJ T;  2OA5 A;  2VWA A;  3KBT A;  2N1G A;  2NWB A;  5HCJ A;  3AE3 A;  2MAW A;  2DWG A;  3QK6 A;  4MAL A;  4JI1 T;  1HG2 A;  5FMN A;  2NP9 A;  3AE8 A;  5C2T A;  3PV0 F;  4Z90 A;  5LCY A;  1VCT A;  3O9X A;  3UU5 A;  1MMG A;  1OED E;  1E2A A;  3UFE A;  4I4T E;  5J2U E;  3ZMT B;  3E08 A;  4UEL A;  5HWY A;  1XDP A;  4I43 B;  2EHO D;  4EB6 E;  4LFB T;  3FXD B;  2XAQ B;  5JDG A;  3K3Q C;  4I0U A;  3L39 A;  1UUR A;  3K1S A;  4QHO A;  4QH5 A;  2ZM6 T;  4ZOL E;  3RIF A;  5KXJ A;  2UUA T;  4ZHQ E;  3MA9 A;  1XMQ T;  2VL0 A;  3P50 A;  5HEH A;  3QOF A;  3UUM A;  2FBW A;  3LDQ B;  1XNQ T;  2CXL A;  3EUH A;  1HS7 A;  3CQX C;  4N78 D;  4DR6 T;  1T8B A;  5HXS A;  4HFI A;  2IDO B;  3X1D A;  1ZHC A;  2ACX A;  4U3C A;  1JNR A;  3LK3 B;  3SWH A;  4E7Z A;  3RIA A;  3ZCJ A;  2YDR A;  3RIU A;  5DJQ C;  5C8Y E;  3PUX F;  3EHZ A;  4JI7 T;  3NRX A;  4CN6 A;  3TLU A;  2JMH A;  3ZT5 A;  2JQH A;  2KWH A;  3UT5 E;  1GQE A;  4JI6 T;  4CI3 B;  2XAF B;  4FI5 A;  2X68 A;  3ZSS A;  4BJN A;  2VQF T;  4MBQ A;  5FVL A;  2UXN B;  2BDE A;  5LHI B;  4TX5 A;  5IYZ E;  2CLY C;  2VK9 A;  3QB5 K;  1Z8U A;  4YJ3 E;  4DR1 T;  4L0R A;  4ILU A;  2BG9 A;  4EYY R;  4CN4 A;  2UUC T;  4BA9 A;  1U4Q A;  4AKH A;  1L0V A;  2X0L B;  3AA0 B;  3L8R A;  4HWI B;  4IIJ E;  1WLX A;  3RRW A;  3V5U A;  3FB2 A;  2WWU A;  1KF6 A;  1LVK A;  1YQ4 A;  4AQF A;  4JBW F;  4MLK A;  4WW0 A;  3FHN A;  1HF8 A;  2VKO A;  4Z91 A;  4GIW A;  1MND A;  4O4I E;  4ASK A;  4CQI A;  2V7K A;  1M7K A;  2WDQ A;  3HKC E;  2R6G F;  4YHJ A;  4YY3 T;  3SFE A;  2X9H A;  3KFW X;  5LYJ E;  4LF5 T;  1VCS A;  3JAD A;  3AA7 B;  1U5P A;  3C64 A;  2VB6 A;  3WAJ A;  2ODU A;  3VU7 H;  4DV5 T;  2ZM2 A;  2LRK A;  3F2E A;  3O4X E;  4GKK T;  3OYX A;  2D2S A;  4H9N C;  3FZM B;  3TLS A;  3Q5X A;  4DR3 T;  4IHJ E;  1MIW A;  5CFB A;  2NW8 A;  5FL0 A;  2YIN A;  2BBJ A;  1YKH B;  4U31 A;  3P4R A;  5L3E B;  1J5E T;  1LVF A;  1HNZ T;  5F5W A;  2JMK A;  4HWF A;  4DUY T;  4JYA T;  3LJC A;  3P4S A;  1VOM A;  4ZI7 E;  2JQK A;  3ZT6 A;  4TNW A;  4MFR A;  5AQK B;  4LFC T;  2MTQ A;  1H7C A;  4YHH T;  3NKZ A;  4OHF A;  4NXN T;  4X66 T;  4GYS A;  2LLY A;  3LBX A;  5JDF A;  3O1H A;  4UXN B;  1I6Z A;  2V6Y A;  4LMJ A;  2L9Q A;  2CXD A;  3AXJ A;  2IUB A;  4ISS A;  2CE7 A;  3LK2 B;  2ZM0 A;  3A5X A;  1QLB A;  5H6Q B;  4HFE A;  5JQG E;  3PJA J;  4F6R C;  5CGM A;  4L9I A;  4IGU A;  2IHR 1;  3LFM A;  1ZEE A;  5M4Y A;  2C5K T;  4LF4 T;  3SS1 A;  4YSY A;  2A2F X;  5EK4 A;  3UUL A;  3MAC A;  1BR4 A;  2XSA A;  1T98 A;  3J7Y q;  2MYS A;  4I50 E;  3UUB A;  4AQY T;  1N36 T;  3C51 A;  2YK0 A;  3UU8 A;  1B7T A;  1IAP A;  5AQP B;  3ZT7 A;  4E7S A;  1HFA A;  1OED C;  3EDV A;  4ADZ A;  2KZ7 B;  5FL1 A;  5KX5 E;  3ZN0 B;  2X0Y A;  2WZH A;  5JVD E;  4U7I A;  2XTL A;  1HNX T;  2CPT A;  2KND A;  3CQC B;  2H3R A;  3N5L A;  4JUY A;  5J0Z A;  2I6H A;  2VKD A;  4UV8 B;  1IBK T;  3P7I A;  1X9B A;  2K9A A;  3Q5W A;  2X67 A;  2KSR A;  3PUA A;  2VVS A;  5L2L A;  1YQ3 A;  2HN2 A;  2V26 A;  2CM0 A;  5JDM A;  1N33 T;  4K0K T;  4U74 A;  4HWH A;  1J1J A;  2V6X A;  4IDP A;  2UUB T;  1Y64 B;  2JIW A;  5LA6 E;  3ZC0 A;  3BK9 A;  2NW7 A;  2IC9 A;  5JDL A;  1D0X A;  5FP3 A;  2EHO B;  3N9L A;  5AQS B;  3KV5 A;  3SFD A;  1WYB A;  1NAF A;  3ANW B;  1KNP A;  4HFV A;  4QX8 B;  2VKH A;  3RYH E;  2LKG A;  4QH1 A;  5AQN B;  4UR9 A;  3I0O A;  2BS2 A;  2SPC A;  2W61 A;  3C98 B;  4QWN B;  2ZM8 A;  2K24 A;  1IBL T;  2PFV A;  5ABF B;  4LFA T;  3PJA A;  1MMN A;  4IE7 A;  1BR2 A;  3UU6 A;  1HX8 A;  1YD8 G;  4U72 A;  4B3M T;  1Z0P A;  1IJ5 A;  3JC6 D;  3OTO T;  2PTF A;  3RYI E;  2MOZ A;  3U78 A;  1ZP0 A;  4JEU B;  4XZC A;  3AEC A;  2BVL A;  3ETU A;  4TWH A;  2E8I A;  5JRC A;  4ZZB A;  4ZS3 A;  3BQI A;  2BKP A;  3A7M A;  3ZMV B;  4LF6 T;  3AA1 B;  3KVB A;  4DV2 T;  2FJB A;  5LB7 B;  2A3D A;  3ZST A;  4H9R C;  2W00 A;  3P4P A;  3F31 A;  2HN1 A;  2XAH B;  2VUR A;  2F4V T;  3HKE E;  2PG8 A;  2WY2 A;  4UEM A;  2XHE B;  4CXY A;  1HR0 T;  3UFG A;  4CI2 B;  4WBO A;  2DLR A;  3AEE A;  2L3L A;  1VRB A;  2LHN A;  2CMR A;  2YDS A;  2BG9 E;  4TUY E;  1E1H B;  2K48 A;  3RHW A;  2WP9 A;  5ABE A;  4X5T A;  3RQU A;  3K3O A;  4ZI2 C;  2H88 A;  4WYV A;  1OED B;  4NUU A;  2QA7 A;  3IHR A;  4EYU A;  1WCR A;  2DCF A;  4O2B E;  3HR0 A;  1US7 B;  2VL8 A;  5DQW A;  5AQF B;  3ZC1 A;  4H63 V;  3WAK A;  2LM2 A;  2VVN A;  3RLF F;  2W62 A;  4DND A;  1T7S A;  4EZ4 A;  3SOL A;  1FIO A;  2WSS V;  4YFS A;  4DV0 T;  3CPZ A;  3QC9 A;  4F8H A;  2IW5 B;  3DTO A;  3C4Z A;  5HYA A;  3V5S A;  5LBM A;  2H7V C;  4UVC B;  2CRB A;  3AB3 B;  2XJ7 A;  4H9Q C;  3CX8 B;  5AQT B;  3TLV A;  5FXV A;  4ERR A;  2KT9 A;  4HKA A;  5AQI B;  2NW9 A;  4CI1 B;  1WR0 A;  3ZN1 B;  3IA3 A;  5AQQ B;  1XWM A;  3AEB A;  2XQ7 A;  3AEG A;  3PU3 A;  5KDM C;  5FY1 A;  3ZMS B;  3MXZ A;  2V6Y B;  2Y6X A;  4P1N A;  4QH4 A;  3FZL B;  4AKG A;  2Q9Q C;  3ONL C;  4JI8 T;  4PK5 A;  3E0Z A;  1W9R A;  4DV6 T;  4WZX A;  2CCQ A;  2DHR A;  4DBR A;  4TWF A;  2DNX A;  4QXH B;  2NTY A;  1S35 A;  1LKX A;  2RA1 A;  3L09 A;  5LHG B;  4EV6 A;  3DP7 A;  5CA0 E;  4TV8 E;  1WR6 A;  3M3Z B;  3ZCI A;  2ACZ A;  4KBM B;  2WU5 A;  3IF8 B;  3AED A;  3U3I A;  5L3B B;  2K5B B;  1IJ6 A;  2FJD A;  2V8S V;  4DUZ T;  2E9X B;  4K0U A;  4L5G A;  4DV1 T;  3IBP A;  5L3F B;  4I55 E;  2C5J A;  3ZMZ B;  2FUP A;  3ZYL A;  5LJN A;  2XQA A;  4X1K E;  4QXB B;  4UF0 B;  3J9X 1;  3BQL A;  4ZS2 A;  2W66 A;  3QNU A;  3KVA A;  1MNE A;  2D0T A;  4AIU A;  3CX7 B;  4AKL A;  4IE0 A;  3OYZ A;  1J5W A;  3I0Q A;  5HEU A;  2M6B A;  3RC3 A;  3RQW A;  2X66 A;  4HFD A;  3ZJ1 A;  3AE2 A;  3KBU A;  3Q2M A;  4BAY B;  5HCM A;  2LEH A;  2YDQ A;  1AJ3 A; 
#chains in the Genus database with same CATH homology
 1M7K A;  3LDQ B;  5AQJ B;  5AQV B;  5AQF B;  5AQU B;  3FZF B;  5AQR B;  5AQO B;  3FZM B;  1M62 A;  1UK5 A;  4HWF A;  1T7S A;  4HWD A;  5AQL B;  1I6Z A;  5AQT B;  3FZH B;  3FZL B;  5AQN B;  5AQH B;  1HX1 B;  2D9D A;  5AQI B;  4HWC A;  5AQP B;  1UGO A;  5AQM B;  3M3Z B;  5AQG B;  4HWH A;  3A8Y C;  4HWI B;  5AQS B;  5AQK B;  5AQQ B;  3FZK B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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