5AQSB

Fragment-based screening of hsp70 sheds light on the functional role of atp-binding site residues
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
113
structure length
113
Chain Sequence
LGSNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
pubmed doi rcsb
molecule tags Chaperone
source organism Homo sapiens
molecule keywords HEAT SHOCK COGNATE 71 KDA PROTEIN
total genus 44
structure length 113
sequence length 113
chains with identical sequence D
ec nomenclature
pdb deposition date 2015-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02179 BAG BAG domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.58.120 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase; Chain G, domain 1 BAG domain 5aqsB00
1M7KA 5AQHB 3FZHB 5AQPB 5AQIB 5AQNB 4HWCA 5AQMB 3FZKB 4HWDA 1T7SA 5AQGB 3LDQB 5AQFB 5AQOB 1UGOA 5AQJB 1M62A 1HX1B 5AQTB 5AQVB 2D9DA 3A8YC 3FZLB 5AQRB 3M3ZB 5AQLB 5AQKB 3FZMB 3FZFB 1I6ZA 4HWFA 5AQUB 5AQQB 1UK5A 4HWIB 4HWHA 5AQSB
chains in the Genus database with same CATH superfamily
3AAEB 3ESLA 4UXNB 4TZ4C 4EEDA 2H7VC 4CQIA 4YSYA 4O2AE 2FBWA 2YK0A 2E5VA 3F31A 5CFBA 5LBQB 5AQLB 2V5CA 4BAYB 3RH3A 4HWFA 4N78D 2H3RA 4DV0T 2W61A 4ASKA 2CWOA 5CGMA 1OEDC 4E7ZA 3RC8A 2CLYB 4KMCA 4I0UA 1EZ3A 4JI6T 3ZLIA 2NTYA 3ZMTB 1XDOA 2XUEA 4DO0A 3O9XA 4QX8B 3NZQA 4JLEA 5JQGE 2IW5B 2WZHA 5DQWA 3P4PA 5HEOA 5KDMC 4A98A 3C51A 3KVBA 3ONJA 4AQYT 4QXCB 3ABVA 3L8RA 2WDRA 4ZS2A 3RIUC 4UF0A 4YHJA 4HEAA 4DBRA 2XQ8A 4XAXB 2XY8B 3Q5WA 4IE5A 3CQCB 3JAEA 5ETWA 5LG4A 3JC6C 2LOPA 2WMOA 3CWZB 2XQ7A 3TLWA 3CQXC 2N2NA 4U7IA 1KNRA 4TX5A 3ZYKA 3UQ4A 3ZSTA 4LFBT 4H63V 3L3PA 2IHR1 1SA0E 5EZYE 4QH5A 4ZI3D 2N9DA 4QHOA 4IHJE 4CXYA 4O4IE 4TV8E 4XZCA 4HWIB 2YDSA 3CX6B 1YKHB 2XQYA 4MHCA 3KV5A 3KBTA 3K3OA 1UURA 4DV3T 5LNKA 5HWYA 4ZOLE 5ABGA 5CA0E 3MK7C 3B13A 5C3JA 3S4UA 3NRYA 3AXJA 3KBUA 1XZYA 4M1PA 1L0VA 3ONLC 2V6YB 3P50A 3OPCA 4ZZCA 2B76A 2V7LA 3AE3A 4IE4A 2EHOB 4EYUA 2CPTA 4EV6A 3PURA 3Q5EA 3RYHE 1Y01A 4A5XA 3DJBA 3RC3A 2NR4A 1KNZA 2P9BA 4PJLA 4DVDA 3LDQB 3CMLA 3EUHA 4QH1A 2ZMAA 1MMDA 2N1GA 4ZEYA 4I43B 4Q25A 2WBLA 4HWHA 2CLYC 5L3FB 2CA5A 5AQIB 4GYSA 4H9OC 1IJ6A 4EOZB 1QLBA 4GK5E 1D1BA 1UGOA 4UVCB 1W0BA 3AE4A 2B1EA 3L39A 3KV9A 1N34T 3M3ZB 2BBHA 2XASB 2WS3A 2ACXA 4COFA 5L4HA 3CIRA 4OYKA 4LF8T 5JR9C 4WZXA 2A9UA 3OYZA 3NKZA 3IBPA 4XBFB 1T98A 2VQFT 2KT9A 3P4RA 4JEUB 1Z0PA 3H37A 4DV2T 4HWCA 2I59A 2LOSA 4FJOA 2V1DB 5LBMA 4O4HE 2ZM0A 4HTEA 2ZM8A 3O1IA 4BJMA 1H7CA 5GONE 4H9QC 3MJXA 2ODUA 4Z91A 3QB5A 5ABFB 2L3LA 3A8YC 5H6RB 5HEHA 5FY7A 4IL4A 3LK2B 3N2KE 1KEYA 4U7YA 2JPFA 3K3NA 3T8OA 1XWMA 2RPAA 4DR4T 3P4QA 2M6IA 2HH7A 5FVLA 1LVKA 4X66T 2X0LB 4DMVA 4HFDA 3SS1A 5LHIB 3SWHA 5J2UE 5J1GA 2CHOA 2EHOC 4CI2B 5IYZE 3RYCE 4DBQA 3K8PC 2BZBA 3RI5A 3QB5K 2QA7A 3LJCA 3EDUA 2H88A 5FL1A 5L3DB 1NAFA 5JDHA 5JH7E 1M7KA 2KWHA 4QXHB 3UFGA 2K24A 4IE0A 2NW9A 3EABA 4HFBA 2R6GF 2D9DA 3ZEFB 3L09A 4CXXA 3C64A 1NWMX 2Q9QB 2VASA 3PDYA 4ZXLA 1BR2A 2F4VT 3E22E 2BDEA 4FI5A 2X9HA 3K1SA 2W62A 3Q5DA 4JBWF 3AECA 5LP6E 2BG9E 1IZNB 2XAFB 2FJDA 2YEVC 2LSJA 1HCIA 3ZMVB 3ZYMA 2CCQA 3E08A 2QYWA 3B5MA 4JI4T 1LVFA 1E1HB 5HXCA 4C90A 4JUYA 2IC9A 1YXRA 1UUSA 4YXDA 2D2SA 2XPKA 4BJNA 3PUWF 3ZJ1A 3EDVA 1YQ3A 4OK0A 2JQKA 4YSXA 3AEBA 2H89A 2VVSA 1G73A 2BVMA 1ZP0A 1Z8UA 3N2OA 2DWGA 4LFCT 2CHNA 5IUXA 4IDNA 5JDGA 1FIOA 3LBXA 3ZN0B 2YN6A 2PFVA 2MYSA 3ZMUB 4GKKT 1UX5A 3KV6A 3E0ZA 3VKGA 1WYCA 5L3EB 5IHYA 5AQFB 4L5GA 3PUXF 4UVAB 4YTMA 1J5WA 3F57A 3FBLA 3ANWB 4TWHA 4O4JE 3VKHA 2J1DG 2H7OA 3I9WA 4JEHB 1HR0T 3RQUA 4B3MT 5FXWA 1Y64B 2LT3A 3IEEA 1M62A 2BS2A 3WI3A 5FNVE 4KHPT 2X9XA 4O8SA 5L4EA 4DUYT 3OYXA 4ILCA 4JI5T 5AQSB 3N9PA 4AQGA 4L0RA 4PK4A 5DQVA 2UXCT 2DL1A 2DLRA 3UU6A 4AKIA 3VHLA 5HEUA 5A1LA 2VK9A 3ZN1B 3U78A 5ABEA 2JJ9A 2OV9A 2QGSA 2JRKA 4EYYR 4DR7T 3J9X1 5HXHA 2A3DA 5LGNB 4HFHA 1T7SA 3WAKA 2Q9QC 2BG9B 2CM0A 3FZFB 3ZSSA 1WR6A 3C4ZA 2ES0A 5F8PA 1LRZA 2Y6XA 2YOEA 2ZM2A 4YY3T 3AE2A 3P4WA 3Q9DA 1HNXT 2HN1A 4Z90A 3EHZA 3CVRA 4ADZA 3EAMA 4E7SA 3IF8B 2YDQA 2PBIA 2LRLA 4F6RC 3SRZA 5LOVE 2DWKA 1WLXA 1XDPA 2HN2A 2RA1A 2CMRA 2LHNA 4X1IE 5LGUB 4OX9T 4GK0E 2KSRA 5AQJB 4NXMT 2YU1A 5EK2A 4TN7B 2ODVA 4YJ3E 2WCAA 2LLYA 1ZEEA 1N36T 3HKCE 5JDLA 3TLVA 4IDQA 2A72A 2LE8A 4KUMB 4DR2T 3MXZA 4A97A 2V8SV 4TNVA 1HTJF 4UF0B 3P4SA 5FYMA 3ZCIA 5LYJE 4QKNA 4P1NA 4U3CA 3GMIA 3ZPOA 3MZKB 4YFSA 3W15B 4ZI2C 5TAOA 2NTXA 3GN5A 4KX6A 3WAJA 3IA3A 5L3GB 3C4WA 2XM1A 2MTQA 4B3ST 1CUNA 4KI0F 4NXNT 4X64T 1QSDA 2E9XC 1GQEA 4I4TE 1V9DA 5FY1A 5KX5E 2WAUA 4NIQA 3JADA 2WP9A 3AEAA 3CK6A 2X0YA 2XQ4A 4O4LE 2LHRA 5AQTB 3PUQA 1WRDA 2MOZA 3D0TA 4DR6T 3AXJB 3RLFF 4TWDA 2YDRA 2V6XA 4WNKA 4HFIA 2BG9C 4QH4A 4EZHA 4UVBB 3OVUA 2CEAA 3U3IA 5AQKB 3HA4A 2G0UA 4HE8A 2AXDS 4UR9A 3P7IA 1NENA 2WY2A 5LHHB 2WU2A 4LFAT 2OA5A 1AJ3A 1VOMA 1DU2A 5L3CB 3AE6A 5JREA 3UUXB 2VVNA 3HI2A 1HNWT 3BQLA 4AI6A 5CJ5A 3V5SA 2ACZA 4X1KE 4DV6T 4TUYE 4AQFC 1JNRA 1HS7A 2C0SA 3KV4A 2LEHA 3AAAB 2D5UA 3HKEE 2LKHA 4B3TT 5DJQC 4JI7T 2LSGA 4G2AA 2Y8DA 4GIWA 3ZJ2A 2LSIA 2HPLA 2DNXA 2X9WA 5ADXL 4CN4A 1E2AA 1NEKA 2LJLA 5BR8T 3I9YA 4DV5T 5JRCA 1FEWA 4C91A 2WDQA 4DIDB 3JC6D 4K0KT 4QXBB 2J4GA 3G06A 5L2LA 3NWIA 3NVOA 2LM2A 3N9MA 2PJQA 1IJ5A 3HR0A 4ILAA 3M65A 4NPPA 1W0AA 2UXBT 4JI0T 3T1YT 2X0HA 2W4XA 5AFUL 1SE7A 3Q5XA 4LF9T 1BR1A 2C5KT 2L8KA 3KINB 2I0MA 4ISSA 2JMHA 5M4YA 2XZEA 2XQ9A 3ETUA 2CE7A 3QC9A 3AA6B 4LF6T 2V7MA 3ZYLA 2C5JA 4AKHA 5EK4A 5HWXA 2W0GA 2XAGB 1HNZT 4HKAA 4PW8A 2VKOA 2OLTA 1FJGT 3NZPA 2VL0A 3PU3A 4DV1T 1UCUA 2XQAA 2V7JA 5LJMA 4EGWA 3H3MA 1XNRT 3P8CD 4MALA 1CHUA 5E0OA 2J62A 5CA1E 2BKPA 5F3JA 4DUZT 2KMFA 1QUUA 3EI0A 3CKDA 2VQET 1D0YA 1X79A 3NBXX 1UX4A 3RRCA 2FUPA 4O2BE 2WZIA 1OEDA 3UULA 2X68A 2KZ7B 5LXTE 3FXDB 2UU9T 4JI1T 1ZKEA 4ZI7E 1S35A 4AKRB 3OTOT 4YHHT 2K9AA 4X1YE 5LG3A 4OHFA 3PUVF 4PFPA 2W66A 4JI8T 2V7IA 4U2ZA 5BMVE 5JDMA 3AVRA 4IDOA 3I0QA 4DR5T 3RIUA 2K48A 5LHGB 2LM9A 3AE8A 4IL9A 4PJNA 4UEMA 3FZKB 4GOUA 4IDPA 3I0OA 3RF1A 1JNZA 1ZOYA 1MIWA 2PG8A 5FXZA 3V5UA 3TKLB 5HAXA 3FZMB 2WM9A 5L47A 1WYBA 3PUGA 3ZC0A 4PK5A 4I55E 4X5TA 1SUMB 2WMNA 3FB2A 4HN9A 5EK3A 4PNIA 4LMKA 3RX6A 5FXXA 1IBMT 2LRKA 4X20E 4KP3C 5HXEA 2CWYA 3RRWA 2IC6A 4ILUA 4JI2T 2V26A 3LBXB 2K3WA 3HKDE 4JV5T 4ZI3C 3VRAA 4GKJT 3UU8A 4F8HA 3JAFA 3UFEA 3PUAA 1YQ4A 1FMWA 5LA6E 2JIWA 4U33A 3GA8A 3LG7A 4H9RC 2BBJA 3AB3B 1XMQT 1J1JA 1VRBA 4IE7A 2E9XA 3GWHA 2IMLA 4IIJE 1D1CA 3UUBA 2EHOD 4CXWA 4V1Av 4DR1T 5FKYA 5IWAT 2C5IT 3RYFE 4X65T 3K3QC 3MKDA 2WU5A 1US7B 1VCSA 2VKDA 2W63A 1ZHCA 5LJNA 3BQKA 3N9LA 2CXLA 5KMGP 3FZLB 3CX8B 5HEJA 1R8IA 2XM2A 1U4QA 5LB7B 1W09A 2JMKA 2VURA 3FZHB 1HX8A 4HWDA 3RIFA 4G63A 3AA1B 4B3RT 2AE9A 4NUVA 4YTPA 5HCMA 2J47A 4YT0A 5AQQB 4U2YA 1ZV4X 1U5PA 4AQFA 5JR9A 1YKEB 1T8BA 2KXPB 3ZT6A 3R6NA 4AISA 2UUAT 2WQYA 2XTLA 2E8IA 2KWIB 2Z6EA 2E5LT 4EB6E 4EEBA 2VB6A 2QVAA 4ISTA 3ZT7A 2BKOA 3ZKRA 4ZS3A 3AAIA 2SPCA 5JR9B 3J7Yq 4AKLA 2FJEA 2RP4A 2L9QA 4B6XA 3KVAA 3SOLA 3T1HT 3RGLA 2X67A 4K0UA 1XNQT 2PTFA 3AA7B 3MACA 5LCYA 2UUBT 1MNDA 3LSVA 2BS4A 4UV8B 2VL8A 3PV0F 2LSKA 2V5DA 3UU4A 3UTKA 4DMWA 3VRBA 2LSYA 3LK42 2W2UA 4PFOA 3PUYF 3VR9A 2YKSA 2X51A 2E2AA 5J0ZA 4GYRA 2BKNA 1J5ET 3F2EA 4WYVA 4HFEA 4IGUA 4H63H 5C8YE 2D0TA 4TNWA 4AKGA 3GN5B 4Z8XA 2V6YA 1BR0A 2NWBA 2UXDT 1MNEA 4TWFA 2EHOA 1YD8G 2HPJA 2XSAA 5AQRB 3NRXA 4ZZBA 1MMGA 5FL0A 4YJ2E 3AEGA 3AVSA 1KNPA 2JQHA 4EZ4A 4JYAT 5AQGB 3FHNA 3ZT5A 4ANJA 5C2TA 4PAGA 2NOXA 4NUUA 2Q9QD 4HFCA 2WB5A 2CBIA 2XAJB 5AQMB 3DP7A 2IDOB 4KHZF 2MPKA 4LMLA 3BQIA 3FXEB 3PUSA 5FVKA 4P0AA 4QX7B 3AEEA 1WFDA 1X9BA 1LKXA 4CI1B 3VU7H 5AQHB 3EVYA 2ZM6T 3LK3B 4LF7T 3RIAA 2I6HA 3C4XA 3QUJA 4YTNA 5F5WA 2XAQB 3OJAA 4H9NC 4IE6A 2BS3A 5JDQA 1KFYA 3RHWA 4UIGA 2WWUA 5CB4E 2IUBA 3ZMSB 1VCTA 5HEGA 2WWVA 4H9SE 3QNUA 1OEDE 4HGAA 5HCJA 1IBKT 4MFRA 3H3AA 2DHRA 3ETVA 3QOFA 4AIUA 1HG2A 4L9IA 2CXDA 2XHEB 3CQGB 5JRCB 3RKOA 3UU3A 1T72A 5ABFA 5AQVB 1D0XA 3MA9A 5JTGA 4BA9A 3AEDA 4CZZB 1D1AA 5FMNA 2W67A 2DI4A 4ZI2D 4ZHQE 1MIYA 2FJAA 4EXTA 1B7TA 3RKGA 3AE1A 1MMAA 1G8XA 3PJAJ 3VR8A 3UUMA 1HX1B 2JQQA 1SHZC 2CBJA 2WDVA 3OBVE 4U31A 3TLSA 3N2GE 1I6ZA 4IT4A 4P0BA 2W00A 3AA0B 1FMVA 2M67A 1W9RA 1YW0A 2XQ6A 4IREA 2NW7A 3QK6A 2E9XD 4CN1A 3N5LA 3TLTA 2X66A 2XQ5A 3N9OA 4A56A 3O4XE 2MAWA 4YSZA 4X62T 1IBLT 5ABHA 3C98B 2VWAA 1OXZA 3HKBE 4DV4T 4P09A 4WBOA 2XAHB 2NW8A 2UXXB 5AQOB 2XJ7A 5JDFA 2Y48B 3PJAA 3KDSE 2IAKA 4OFZA 4KBMB 2MBGA 4YLHA 2Q9QA 4DV7T 5AQUB 1N33T 3PTRB 3I1AA 3RYIE 2X9YA 4UV9B 3AEFA 1WR0A 5FXVA 4WBNE 3N9NA 4J2CA 3A5XA 3UUNA 1HF8A 3Q2MA 2GK9A 3ZCJA 1N32T 2ZLYA 2IIUA 3SFDA 4ILBA 2QRXA 4LMJA 3UU5A 3N9QA 3CPZA 3TLUA 4I50E 2UXNB 1OEDB 4WW0A 3SFEA 2YU2A 2NP9A 4U74A 3B57A 4LF5T 4CI3B 2A2FX 3PU8A 1HG5A 3FBZA 1E7PA 2YINA 3R84B 5FY0A 3O1HA 3C50A 4AXPA 5DABA 2K5BB 1OWAA 4TV9E 5LMUT 1D0ZA 4PJMA 2KNDA 4U72A 3ONXA 4ERRA 2CXFA 2XQ3A 4CN6A 4DR3T 1MIVA 2CRBA 1KK7A 1I94T 3ZMZB 1O3XA 5FP3A 1IAPA 4LF4T 4IDZA 2VKHA 3ANWA 5KXJA 2LKGA 5LGTB 3UT5E 4EAHA 2XSBA 1S94A 3OKQA 5L3BB 3HL6A 3PE0A 3DTOA 5LMNT 2D0UA 5JVDE 5HYAA 4PJJA 4HFVA 1HFAA 4H9PC 3AE5A 5JDNA 1XMOT 3O1JA 2DCFA 3A7MA 3AE7A 3ZC1A 5AQPB 3LFMA 5AQNB 4UELA 2BVLA 5H6QB 3RPUA 3AE9A 5HXSA 3RQWA 2M6BA 3UQ7A 2HHHT 4PK6A 4DNDA 2UUCT 3JCFA 4JI3T 3CX7B 1WCRA 3PUZF 2FJBA 5J2TE 2E9XB 4EIWA 2VKJA 5HXRA 3KFWX 2KLQA 4MBQA 3X1DA 1BR4A 4OYJA 2V7KA 2BG9A 1KF6A 2JQ9A 2KINB 3IHRA 2WSSV 4QWNB 1MMNA 3BK9A 1UK5A 4MLKA
chains in the Genus database with same CATH topology
1M7KA 5AQHB 3FZHB 5AQPB 5AQIB 5AQNB 4HWCA 5AQMB 3FZKB 4HWDA 1T7SA 5AQGB 3LDQB 5AQFB 5AQOB 1UGOA 5AQJB 1M62A 1HX1B 5AQTB 5AQVB 2D9DA 3A8YC 3FZLB 5AQRB 3M3ZB 5AQLB 5AQKB 3FZMB 3FZFB 1I6ZA 4HWFA 5AQUB 5AQQB 1UK5A 4HWIB 4HWHA 5AQSB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M7K A;  5AQH B;  3FZH B;  5AQP B;  5AQI B;  5AQN B;  4HWC A;  5AQM B;  3FZK B;  4HWD A;  1T7S A;  5AQG B;  3LDQ B;  5AQF B;  5AQO B;  1UGO A;  5AQJ B;  1M62 A;  1HX1 B;  5AQT B;  5AQV B;  2D9D A;  3A8Y C;  3FZL B;  5AQR B;  3M3Z B;  5AQL B;  5AQK B;  3FZM B;  3FZF B;  1I6Z A;  4HWF A;  5AQU B;  5AQQ B;  1UK5 A;  4HWI B;  4HWH A;  5AQS B; 
#chains in the Genus database with same CATH topology
 3AAE B;  3ESL A;  4UXN B;  4TZ4 C;  4EED A;  2H7V C;  4CQI A;  4YSY A;  4O2A E;  2FBW A;  2YK0 A;  2E5V A;  3F31 A;  5CFB A;  5LBQ B;  5AQL B;  2V5C A;  4BAY B;  3RH3 A;  4HWF A;  4N78 D;  2H3R A;  4DV0 T;  2W61 A;  4ASK A;  2CWO A;  5CGM A;  1OED C;  4E7Z A;  3RC8 A;  2CLY B;  4KMC A;  4I0U A;  1EZ3 A;  4JI6 T;  3ZLI A;  2NTY A;  3ZMT B;  1XDO A;  2XUE A;  4DO0 A;  3O9X A;  4QX8 B;  3NZQ A;  4JLE A;  5JQG E;  2IW5 B;  2WZH A;  5DQW A;  3P4P A;  5HEO A;  5KDM C;  4A98 A;  3C51 A;  3KVB A;  3ONJ A;  4AQY T;  4QXC B;  3ABV A;  3L8R A;  2WDR A;  4ZS2 A;  3RIU C;  4UF0 A;  4YHJ A;  4HEA A;  4DBR A;  2XQ8 A;  4XAX B;  2XY8 B;  3Q5W A;  4IE5 A;  3CQC B;  3JAE A;  5ETW A;  5LG4 A;  3JC6 C;  2LOP A;  2WMO A;  3CWZ B;  2XQ7 A;  3TLW A;  3CQX C;  2N2N A;  4U7I A;  1KNR A;  4TX5 A;  3ZYK A;  3UQ4 A;  3ZST A;  4LFB T;  4H63 V;  3L3P A;  2IHR 1;  1SA0 E;  5EZY E;  4QH5 A;  4ZI3 D;  2N9D A;  4QHO A;  4IHJ E;  4CXY A;  4O4I E;  4TV8 E;  4XZC A;  4HWI B;  2YDS A;  3CX6 B;  1YKH B;  2XQY A;  4MHC A;  3KV5 A;  3KBT A;  3K3O A;  1UUR A;  4DV3 T;  5LNK A;  5HWY A;  4ZOL E;  5ABG A;  5CA0 E;  3MK7 C;  3B13 A;  5C3J A;  3S4U A;  3NRY A;  3AXJ A;  3KBU A;  1XZY A;  4M1P A;  1L0V A;  3ONL C;  2V6Y B;  3P50 A;  3OPC A;  4ZZC A;  2B76 A;  2V7L A;  3AE3 A;  4IE4 A;  2EHO B;  4EYU A;  2CPT A;  4EV6 A;  3PUR A;  3Q5E A;  3RYH E;  1Y01 A;  4A5X A;  3DJB A;  3RC3 A;  2NR4 A;  1KNZ A;  2P9B A;  4PJL A;  4DVD A;  3LDQ B;  3CML A;  3EUH A;  4QH1 A;  2ZMA A;  1MMD A;  2N1G A;  4ZEY A;  4I43 B;  4Q25 A;  2WBL A;  4HWH A;  2CLY C;  5L3F B;  2CA5 A;  5AQI B;  4GYS A;  4H9O C;  1IJ6 A;  4EOZ B;  1QLB A;  4GK5 E;  1D1B A;  1UGO A;  4UVC B;  1W0B A;  3AE4 A;  2B1E A;  3L39 A;  3KV9 A;  1N34 T;  3M3Z B;  2BBH A;  2XAS B;  2WS3 A;  2ACX A;  4COF A;  5L4H A;  3CIR A;  4OYK A;  4LF8 T;  5JR9 C;  4WZX A;  2A9U A;  3OYZ A;  3NKZ A;  3IBP A;  4XBF B;  1T98 A;  2VQF T;  2KT9 A;  3P4R A;  4JEU B;  1Z0P A;  3H37 A;  4DV2 T;  4HWC A;  2I59 A;  2LOS A;  4FJO A;  2V1D B;  5LBM A;  4O4H E;  2ZM0 A;  4HTE A;  2ZM8 A;  3O1I A;  4BJM A;  1H7C A;  5GON E;  4H9Q C;  3MJX A;  2ODU A;  4Z91 A;  3QB5 A;  5ABF B;  2L3L A;  3A8Y C;  5H6R B;  5HEH A;  5FY7 A;  4IL4 A;  3LK2 B;  3N2K E;  1KEY A;  4U7Y A;  2JPF A;  3K3N A;  3T8O A;  1XWM A;  2RPA A;  4DR4 T;  3P4Q A;  2M6I A;  2HH7 A;  5FVL A;  1LVK A;  4X66 T;  2X0L B;  4DMV A;  4HFD A;  3SS1 A;  5LHI B;  3SWH A;  5J2U E;  5J1G A;  2CHO A;  2EHO C;  4CI2 B;  5IYZ E;  3RYC E;  4DBQ A;  3K8P C;  2BZB A;  3RI5 A;  3QB5 K;  2QA7 A;  3LJC A;  3EDU A;  2H88 A;  5FL1 A;  5L3D B;  1NAF A;  5JDH A;  5JH7 E;  1M7K A;  2KWH A;  4QXH B;  3UFG A;  2K24 A;  4IE0 A;  2NW9 A;  3EAB A;  4HFB A;  2R6G F;  2D9D A;  3ZEF B;  3L09 A;  4CXX A;  3C64 A;  1NWM X;  2Q9Q B;  2VAS A;  3PDY A;  4ZXL A;  1BR2 A;  2F4V T;  3E22 E;  2BDE A;  4FI5 A;  2X9H A;  3K1S A;  2W62 A;  3Q5D A;  4JBW F;  3AEC A;  5LP6 E;  2BG9 E;  1IZN B;  2XAF B;  2FJD A;  2YEV C;  2LSJ A;  1HCI A;  3ZMV B;  3ZYM A;  2CCQ A;  3E08 A;  2QYW A;  3B5M A;  4JI4 T;  1LVF A;  1E1H B;  5HXC A;  4C90 A;  4JUY A;  2IC9 A;  1YXR A;  1UUS A;  4YXD A;  2D2S A;  2XPK A;  4BJN A;  3PUW F;  3ZJ1 A;  3EDV A;  1YQ3 A;  4OK0 A;  2JQK A;  4YSX A;  3AEB A;  2H89 A;  2VVS A;  1G73 A;  2BVM A;  1ZP0 A;  1Z8U A;  3N2O A;  2DWG A;  4LFC T;  2CHN A;  5IUX A;  4IDN A;  5JDG A;  1FIO A;  3LBX A;  3ZN0 B;  2YN6 A;  2PFV A;  2MYS A;  3ZMU B;  4GKK T;  1UX5 A;  3KV6 A;  3E0Z A;  3VKG A;  1WYC A;  5L3E B;  5IHY A;  5AQF B;  4L5G A;  3PUX F;  4UVA B;  4YTM A;  1J5W A;  3F57 A;  3FBL A;  3ANW B;  4TWH A;  4O4J E;  3VKH A;  2J1D G;  2H7O A;  3I9W A;  4JEH B;  1HR0 T;  3RQU A;  4B3M T;  5FXW A;  1Y64 B;  2LT3 A;  3IEE A;  1M62 A;  2BS2 A;  3WI3 A;  5FNV E;  4KHP T;  2X9X A;  4O8S A;  5L4E A;  4DUY T;  3OYX A;  4ILC A;  4JI5 T;  5AQS B;  3N9P A;  4AQG A;  4L0R A;  4PK4 A;  5DQV A;  2UXC T;  2DL1 A;  2DLR A;  3UU6 A;  4AKI A;  3VHL A;  5HEU A;  5A1L A;  2VK9 A;  3ZN1 B;  3U78 A;  5ABE A;  2JJ9 A;  2OV9 A;  2QGS A;  2JRK A;  4EYY R;  4DR7 T;  3J9X 1;  5HXH A;  2A3D A;  5LGN B;  4HFH A;  1T7S A;  3WAK A;  2Q9Q C;  2BG9 B;  2CM0 A;  3FZF B;  3ZSS A;  1WR6 A;  3C4Z A;  2ES0 A;  5F8P A;  1LRZ A;  2Y6X A;  2YOE A;  2ZM2 A;  4YY3 T;  3AE2 A;  3P4W A;  3Q9D A;  1HNX T;  2HN1 A;  4Z90 A;  3EHZ A;  3CVR A;  4ADZ A;  3EAM A;  4E7S A;  3IF8 B;  2YDQ A;  2PBI A;  2LRL A;  4F6R C;  3SRZ A;  5LOV E;  2DWK A;  1WLX A;  1XDP A;  2HN2 A;  2RA1 A;  2CMR A;  2LHN A;  4X1I E;  5LGU B;  4OX9 T;  4GK0 E;  2KSR A;  5AQJ B;  4NXM T;  2YU1 A;  5EK2 A;  4TN7 B;  2ODV A;  4YJ3 E;  2WCA A;  2LLY A;  1ZEE A;  1N36 T;  3HKC E;  5JDL A;  3TLV A;  4IDQ A;  2A72 A;  2LE8 A;  4KUM B;  4DR2 T;  3MXZ A;  4A97 A;  2V8S V;  4TNV A;  1HTJ F;  4UF0 B;  3P4S A;  5FYM A;  3ZCI A;  5LYJ E;  4QKN A;  4P1N A;  4U3C A;  3GMI A;  3ZPO A;  3MZK B;  4YFS A;  3W15 B;  4ZI2 C;  5TAO A;  2NTX A;  3GN5 A;  4KX6 A;  3WAJ A;  3IA3 A;  5L3G B;  3C4W A;  2XM1 A;  2MTQ A;  4B3S T;  1CUN A;  4KI0 F;  4NXN T;  4X64 T;  1QSD A;  2E9X C;  1GQE A;  4I4T E;  1V9D A;  5FY1 A;  5KX5 E;  2WAU A;  4NIQ A;  3JAD A;  2WP9 A;  3AEA A;  3CK6 A;  2X0Y A;  2XQ4 A;  4O4L E;  2LHR A;  5AQT B;  3PUQ A;  1WRD A;  2MOZ A;  3D0T A;  4DR6 T;  3AXJ B;  3RLF F;  4TWD A;  2YDR A;  2V6X A;  4WNK A;  4HFI A;  2BG9 C;  4QH4 A;  4EZH A;  4UVB B;  3OVU A;  2CEA A;  3U3I A;  5AQK B;  3HA4 A;  2G0U A;  4HE8 A;  2AXD S;  4UR9 A;  3P7I A;  1NEN A;  2WY2 A;  5LHH B;  2WU2 A;  4LFA T;  2OA5 A;  1AJ3 A;  1VOM A;  1DU2 A;  5L3C B;  3AE6 A;  5JRE A;  3UUX B;  2VVN A;  3HI2 A;  1HNW T;  3BQL A;  4AI6 A;  5CJ5 A;  3V5S A;  2ACZ A;  4X1K E;  4DV6 T;  4TUY E;  4AQF C;  1JNR A;  1HS7 A;  2C0S A;  3KV4 A;  2LEH A;  3AAA B;  2D5U A;  3HKE E;  2LKH A;  4B3T T;  5DJQ C;  4JI7 T;  2LSG A;  4G2A A;  2Y8D A;  4GIW A;  3ZJ2 A;  2LSI A;  2HPL A;  2DNX A;  2X9W A;  5ADX L;  4CN4 A;  1E2A A;  1NEK A;  2LJL A;  5BR8 T;  3I9Y A;  4DV5 T;  5JRC A;  1FEW A;  4C91 A;  2WDQ A;  4DID B;  3JC6 D;  4K0K T;  4QXB B;  2J4G A;  3G06 A;  5L2L A;  3NWI A;  3NVO A;  2LM2 A;  3N9M A;  2PJQ A;  1IJ5 A;  3HR0 A;  4ILA A;  3M65 A;  4NPP A;  1W0A A;  2UXB T;  4JI0 T;  3T1Y T;  2X0H A;  2W4X A;  5AFU L;  1SE7 A;  3Q5X A;  4LF9 T;  1BR1 A;  2C5K T;  2L8K A;  3KIN B;  2I0M A;  4ISS A;  2JMH A;  5M4Y A;  2XZE A;  2XQ9 A;  3ETU A;  2CE7 A;  3QC9 A;  3AA6 B;  4LF6 T;  2V7M A;  3ZYL A;  2C5J A;  4AKH A;  5EK4 A;  5HWX A;  2W0G A;  2XAG B;  1HNZ T;  4HKA A;  4PW8 A;  2VKO A;  2OLT A;  1FJG T;  3NZP A;  2VL0 A;  3PU3 A;  4DV1 T;  1UCU A;  2XQA A;  2V7J A;  5LJM A;  4EGW A;  3H3M A;  1XNR T;  3P8C D;  4MAL A;  1CHU A;  5E0O A;  2J62 A;  5CA1 E;  2BKP A;  5F3J A;  4DUZ T;  2KMF A;  1QUU A;  3EI0 A;  3CKD A;  2VQE T;  1D0Y A;  1X79 A;  3NBX X;  1UX4 A;  3RRC A;  2FUP A;  4O2B E;  2WZI A;  1OED A;  3UUL A;  2X68 A;  2KZ7 B;  5LXT E;  3FXD B;  2UU9 T;  4JI1 T;  1ZKE A;  4ZI7 E;  1S35 A;  4AKR B;  3OTO T;  4YHH T;  2K9A A;  4X1Y E;  5LG3 A;  4OHF A;  3PUV F;  4PFP A;  2W66 A;  4JI8 T;  2V7I A;  4U2Z A;  5BMV E;  5JDM A;  3AVR A;  4IDO A;  3I0Q A;  4DR5 T;  3RIU A;  2K48 A;  5LHG B;  2LM9 A;  3AE8 A;  4IL9 A;  4PJN A;  4UEM A;  3FZK B;  4GOU A;  4IDP A;  3I0O A;  3RF1 A;  1JNZ A;  1ZOY A;  1MIW A;  2PG8 A;  5FXZ A;  3V5U A;  3TKL B;  5HAX A;  3FZM B;  2WM9 A;  5L47 A;  1WYB A;  3PUG A;  3ZC0 A;  4PK5 A;  4I55 E;  4X5T A;  1SUM B;  2WMN A;  3FB2 A;  4HN9 A;  5EK3 A;  4PNI A;  4LMK A;  3RX6 A;  5FXX A;  1IBM T;  2LRK A;  4X20 E;  4KP3 C;  5HXE A;  2CWY A;  3RRW A;  2IC6 A;  4ILU A;  4JI2 T;  2V26 A;  3LBX B;  2K3W A;  3HKD E;  4JV5 T;  4ZI3 C;  3VRA A;  4GKJ T;  3UU8 A;  4F8H A;  3JAF A;  3UFE A;  3PUA A;  1YQ4 A;  1FMW A;  5LA6 E;  2JIW A;  4U33 A;  3GA8 A;  3LG7 A;  4H9R C;  2BBJ A;  3AB3 B;  1XMQ T;  1J1J A;  1VRB A;  4IE7 A;  2E9X A;  3GWH A;  2IML A;  4IIJ E;  1D1C A;  3UUB A;  2EHO D;  4CXW A;  4V1A v;  4DR1 T;  5FKY A;  5IWA T;  2C5I T;  3RYF E;  4X65 T;  3K3Q C;  3MKD A;  2WU5 A;  1US7 B;  1VCS A;  2VKD A;  2W63 A;  1ZHC A;  5LJN A;  3BQK A;  3N9L A;  2CXL A;  5KMG P;  3FZL B;  3CX8 B;  5HEJ A;  1R8I A;  2XM2 A;  1U4Q A;  5LB7 B;  1W09 A;  2JMK A;  2VUR A;  3FZH B;  1HX8 A;  4HWD A;  3RIF A;  4G63 A;  3AA1 B;  4B3R T;  2AE9 A;  4NUV A;  4YTP A;  5HCM A;  2J47 A;  4YT0 A;  5AQQ B;  4U2Y A;  1ZV4 X;  1U5P A;  4AQF A;  5JR9 A;  1YKE B;  1T8B A;  2KXP B;  3ZT6 A;  3R6N A;  4AIS A;  2UUA T;  2WQY A;  2XTL A;  2E8I A;  2KWI B;  2Z6E A;  2E5L T;  4EB6 E;  4EEB A;  2VB6 A;  2QVA A;  4IST A;  3ZT7 A;  2BKO A;  3ZKR A;  4ZS3 A;  3AAI A;  2SPC A;  5JR9 B;  3J7Y q;  4AKL A;  2FJE A;  2RP4 A;  2L9Q A;  4B6X A;  3KVA A;  3SOL A;  3T1H T;  3RGL A;  2X67 A;  4K0U A;  1XNQ T;  2PTF A;  3AA7 B;  3MAC A;  5LCY A;  2UUB T;  1MND A;  3LSV A;  2BS4 A;  4UV8 B;  2VL8 A;  3PV0 F;  2LSK A;  2V5D A;  3UU4 A;  3UTK A;  4DMW A;  3VRB A;  2LSY A;  3LK4 2;  2W2U A;  4PFO A;  3PUY F;  3VR9 A;  2YKS A;  2X51 A;  2E2A A;  5J0Z A;  4GYR A;  2BKN A;  1J5E T;  3F2E A;  4WYV A;  4HFE A;  4IGU A;  4H63 H;  5C8Y E;  2D0T A;  4TNW A;  4AKG A;  3GN5 B;  4Z8X A;  2V6Y A;  1BR0 A;  2NWB A;  2UXD T;  1MNE A;  4TWF A;  2EHO A;  1YD8 G;  2HPJ A;  2XSA A;  5AQR B;  3NRX A;  4ZZB A;  1MMG A;  5FL0 A;  4YJ2 E;  3AEG A;  3AVS A;  1KNP A;  2JQH A;  4EZ4 A;  4JYA T;  5AQG B;  3FHN A;  3ZT5 A;  4ANJ A;  5C2T A;  4PAG A;  2NOX A;  4NUU A;  2Q9Q D;  4HFC A;  2WB5 A;  2CBI A;  2XAJ B;  5AQM B;  3DP7 A;  2IDO B;  4KHZ F;  2MPK A;  4LML A;  3BQI A;  3FXE B;  3PUS A;  5FVK A;  4P0A A;  4QX7 B;  3AEE A;  1WFD A;  1X9B A;  1LKX A;  4CI1 B;  3VU7 H;  5AQH B;  3EVY A;  2ZM6 T;  3LK3 B;  4LF7 T;  3RIA A;  2I6H A;  3C4X A;  3QUJ A;  4YTN A;  5F5W A;  2XAQ B;  3OJA A;  4H9N C;  4IE6 A;  2BS3 A;  5JDQ A;  1KFY A;  3RHW A;  4UIG A;  2WWU A;  5CB4 E;  2IUB A;  3ZMS B;  1VCT A;  5HEG A;  2WWV A;  4H9S E;  3QNU A;  1OED E;  4HGA A;  5HCJ A;  1IBK T;  4MFR A;  3H3A A;  2DHR A;  3ETV A;  3QOF A;  4AIU A;  1HG2 A;  4L9I A;  2CXD A;  2XHE B;  3CQG B;  5JRC B;  3RKO A;  3UU3 A;  1T72 A;  5ABF A;  5AQV B;  1D0X A;  3MA9 A;  5JTG A;  4BA9 A;  3AED A;  4CZZ B;  1D1A A;  5FMN A;  2W67 A;  2DI4 A;  4ZI2 D;  4ZHQ E;  1MIY A;  2FJA A;  4EXT A;  1B7T A;  3RKG A;  3AE1 A;  1MMA A;  1G8X A;  3PJA J;  3VR8 A;  3UUM A;  1HX1 B;  2JQQ A;  1SHZ C;  2CBJ A;  2WDV A;  3OBV E;  4U31 A;  3TLS A;  3N2G E;  1I6Z A;  4IT4 A;  4P0B A;  2W00 A;  3AA0 B;  1FMV A;  2M67 A;  1W9R A;  1YW0 A;  2XQ6 A;  4IRE A;  2NW7 A;  3QK6 A;  2E9X D;  4CN1 A;  3N5L A;  3TLT A;  2X66 A;  2XQ5 A;  3N9O A;  4A56 A;  3O4X E;  2MAW A;  4YSZ A;  4X62 T;  1IBL T;  5ABH A;  3C98 B;  2VWA A;  1OXZ A;  3HKB E;  4DV4 T;  4P09 A;  4WBO A;  2XAH B;  2NW8 A;  2UXX B;  5AQO B;  2XJ7 A;  5JDF A;  2Y48 B;  3PJA A;  3KDS E;  2IAK A;  4OFZ A;  4KBM B;  2MBG A;  4YLH A;  2Q9Q A;  4DV7 T;  5AQU B;  1N33 T;  3PTR B;  3I1A A;  3RYI E;  2X9Y A;  4UV9 B;  3AEF A;  1WR0 A;  5FXV A;  4WBN E;  3N9N A;  4J2C A;  3A5X A;  3UUN A;  1HF8 A;  3Q2M A;  2GK9 A;  3ZCJ A;  1N32 T;  2ZLY A;  2IIU A;  3SFD A;  4ILB A;  2QRX A;  4LMJ A;  3UU5 A;  3N9Q A;  3CPZ A;  3TLU A;  4I50 E;  2UXN B;  1OED B;  4WW0 A;  3SFE A;  2YU2 A;  2NP9 A;  4U74 A;  3B57 A;  4LF5 T;  4CI3 B;  2A2F X;  3PU8 A;  1HG5 A;  3FBZ A;  1E7P A;  2YIN A;  3R84 B;  5FY0 A;  3O1H A;  3C50 A;  4AXP A;  5DAB A;  2K5B B;  1OWA A;  4TV9 E;  5LMU T;  1D0Z A;  4PJM A;  2KND A;  4U72 A;  3ONX A;  4ERR A;  2CXF A;  2XQ3 A;  4CN6 A;  4DR3 T;  1MIV A;  2CRB A;  1KK7 A;  1I94 T;  3ZMZ B;  1O3X A;  5FP3 A;  1IAP A;  4LF4 T;  4IDZ A;  2VKH A;  3ANW A;  5KXJ A;  2LKG A;  5LGT B;  3UT5 E;  4EAH A;  2XSB A;  1S94 A;  3OKQ A;  5L3B B;  3HL6 A;  3PE0 A;  3DTO A;  5LMN T;  2D0U A;  5JVD E;  5HYA A;  4PJJ A;  4HFV A;  1HFA A;  4H9P C;  3AE5 A;  5JDN A;  1XMO T;  3O1J A;  2DCF A;  3A7M A;  3AE7 A;  3ZC1 A;  5AQP B;  3LFM A;  5AQN B;  4UEL A;  2BVL A;  5H6Q B;  3RPU A;  3AE9 A;  5HXS A;  3RQW A;  2M6B A;  3UQ7 A;  2HHH T;  4PK6 A;  4DND A;  2UUC T;  3JCF A;  4JI3 T;  3CX7 B;  1WCR A;  3PUZ F;  2FJB A;  5J2T E;  2E9X B;  4EIW A;  2VKJ A;  5HXR A;  3KFW X;  2KLQ A;  4MBQ A;  3X1D A;  1BR4 A;  4OYJ A;  2V7K A;  2BG9 A;  1KF6 A;  2JQ9 A;  2KIN B;  3IHR A;  2WSS V;  4QWN B;  1MMN A;  3BK9 A;  1UK5 A;  4MLK A; 
#chains in the Genus database with same CATH homology
 1M7K A;  5AQH B;  3FZH B;  5AQP B;  5AQI B;  5AQN B;  4HWC A;  5AQM B;  3FZK B;  4HWD A;  1T7S A;  5AQG B;  3LDQ B;  5AQF B;  5AQO B;  1UGO A;  5AQJ B;  1M62 A;  1HX1 B;  5AQT B;  5AQV B;  2D9D A;  3A8Y C;  3FZL B;  5AQR B;  3M3Z B;  5AQL B;  5AQK B;  3FZM B;  3FZF B;  1I6Z A;  4HWF A;  5AQU B;  5AQQ B;  1UK5 A;  4HWI B;  4HWH A;  5AQS B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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