5AQVB

Fragment-based screening of hsp70 sheds light on the functional role of atp-binding site residues
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
115
structure length
115
Chain Sequence
GPLGSNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
pubmed doi rcsb
molecule tags Chaperone
source organism Homo sapiens
molecule keywords HEAT SHOCK COGNATE 71 KDA PROTEIN
total genus 47
structure length 115
sequence length 115
ec nomenclature
pdb deposition date 2015-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02179 BAG BAG domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.58.120 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase; Chain G, domain 1 BAG domain 5aqvB00
5AQOB 5AQNB 5AQGB 3M3ZB 4HWCA 1HX1B 5AQMB 1I6ZA 3FZKB 4HWDA 1M7KA 5AQRB 1UK5A 3A8YC 5AQLB 5AQUB 3FZFB 4HWIB 5AQQB 1M62A 1T7SA 3LDQB 3FZHB 5AQSB 5AQFB 5AQPB 5AQVB 2D9DA 3FZLB 5AQJB 3FZMB 5AQIB 5AQHB 5AQTB 5AQKB 1UGOA 4HWFA 4HWHA
chains in the Genus database with same CATH superfamily
4IGUA 3KDSE 3N2OA 5KXJA 2LLYA 2Q9QA 3BQIA 4KX6A 3TLVA 1NWMX 2CBIA 4LMLA 4ILUA 3ZT5A 3CMLA 1HNZT 1IJ6A 3LBXA 4PAGA 4DIDB 2LT3A 3N9LA 4XZCA 5HEHA 1BR4A 4P0AA 2YU1A 2VVNA 1L0VA 5DJQC 4B3RT 2ZLYA 4B3ST 5AQVB 4ILBA 3PUGA 5HCJA 5LXTE 4AKRB 4HEAA 4H9QC 4UVAB 3TLTA 3S4UA 2KSRA 4ZEYA 5L3GB 5EK2A 3ZT7A 3KFWX 4IL4A 4G2AA 2NW8A 3UFGA 3UUMA 3GA8A 2UXNB 5IUXA 2X68A 2XAHB 4U7IA 4JI4T 2CMRA 4HFCA 3RQWA 2Q9QD 4IDNA 5AQGB 4IDQA 4IE5A 1I6ZA 1UCUA 1BR2A 4IREA 2DI4A 2JMKA 4TV9E 2EHOA 3ETVA 4DVDA 2E5LT 2V7MA 5LJMA 3PUQA 4QKNA 3BQKA 2WU5A 4CQIA 2LM2A 3PUAA 5J1GA 3ZMVB 1D0ZA 5AFUL 1T8BA 1YKEB 3RH3A 4E7ZA 3CQXC 4UF0A 4BAYB 2FUPA 2PTFA 3PUYF 4U72A 4AIUA 5FXVA 3VKGA 1YXRA 1N33T 1HCIA 2XM2A 3OKQA 4DR2T 4LFBT 4U2ZA 3V5SA 2MPKA 5FXWA 3LK42 5EK3A 3R6NA 2XY8B 2VQET 2WAUA 4AQFA 3LFMA 2XAFB 3O4XE 4HFEA 2WY2A 2CA5A 4YJ3E 4ADZA 3UUNA 3L39A 2XSAA 2I0MA 2BKPA 1W9RA 4MFRA 4PJNA 1XZYA 4BA9A 5H6QB 5A1LA 4FJOA 1M62A 2X0HA 3AEFA 4UIGA 5AQSB 5LHIB 1WYBA 2BG9A 5LCYA 3JAEA 4L5GA 3NWIA 3RRCA 3Q5WA 3Q2MA 3RIFA 2IC6A 3E22E 2WDQA 2KLQA 4ANJA 3RYHE 1IAPA 1UURA 2XZEA 4LF6T 2LM9A 1ZOYA 2IIUA 1HS7A 4U74A 3FZKB 1W09A 1NAFA 4H9RC 4X20E 3LJCA 4DV5T 4OK0A 2VURA 3AEEA 3UULA 5L3CB 2YINA 4HFIA 4UEMA 3ZSTA 2ZM8A 3ONXA 2C5JA 2ZM0A 3ZSSA 4UR9A 5HXEA 3EHZA 4QH1A 2W63A 2MAWA 2FJEA 5FNVE 3SFDA 1NEKA 2QRXA 3RQUA 2V5CA 4QXHB 5FMNA 2N2NA 4UV8B 1KFYA 2C0SA 2LSJA 5LGUB 4MBQA 2YDQA 4YSXA 2G0UA 3N9QA 4DV6T 4C91A 5IHYA 3KVAA 4ISTA 2ZM6T 4E7SA 2X67A 4ZHQE 2LSGA 2W62A 5FL0A 5HYAA 5LOVE 4CN4A 1ZHCA 3HKBE 5FY7A 5LA6E 4DMVA 1Y64B 2IUBA 4AI6A 5HEJA 3C51A 3QNUA 4XBFB 3AE3A 3DP7A 1D1CA 1HTJF 4DR1T 5DABA 4ZS2A 5JRCA 2HH7A 2WP9A 1QLBA 4CXYA 4LFAT 3MKDA 3T1YT 2MTQA 1I94T 3CX8B 3ZEFB 4EGWA 4TZ4C 2DLRA 5IWAT 4EYUA 3PUZF 2KNDA 5JDMA 3FZLB 5AQJB 4EXTA 5AQIB 4DR5T 3V5UA 1D0YA 5AQKB 5AQRB 4CN1A 2BS3A 1CHUA 4HFBA 5KDMC 2VKOA 3AAIA 1ZV4X 4TV8E 3PJAJ 1JNZA 3FZFB 2Q9QC 3N5LA 3AA7B 2R6GF 5J2TE 4L9IA 3N9OA 2LOSA 3OBVE 2X0LB 5HCMA 3UU3A 2QVAA 4X1KE 5DQWA 3KINB 4I4TE 4WZXA 4OHFA 2NOXA 3HR0A 4N78D 5KX5E 4KP3C 4HKAA 3PURA 1QUUA 2XPKA 5FXXA 2BVLA 4IIJE 3AAAB 3J7Yq 3VHLA 1M7KA 3KV6A 5JDGA 4PJLA 4MALA 4DR7T 3AEAA 4JI2T 4PNIA 2DL1A 2JRKA 4A5XA 2JQ9A 3ZYLA 4X64T 2JJ9A 4HWHA 2N1GA 3UFEA 4U3CA 3TLWA 2HN1A 5TAOA 2C5KT 5L3EB 3RC3A 5L4HA 4QH5A 2BS4A 1OEDB 2JQKA 4HWIB 4LF9T 1U4QA 4IDOA 4FI5A 5LGNB 3QB5A 4M1PA 1WR6A 2EHOC 2HHHT 3EABA 4O4JE 2VQFT 3PE0A 3KBUA 4YTMA 3MJXA 3C64A 4O4LE 5CFBA 5HXSA 4G63A 5ABFB 5J2UE 4AQGA 2J1DG 2HPJA 2QGSA 2XQYA 4X66T 3OTOT 2WWUA 2WQYA 4I43B 3H3MA 2Y8DA 4IE6A 1BR0A 2J62A 3DJBA 1WRDA 3OYXA 4AQFC 3H3AA 3SWHA 4O4IE 5JDQA 2GK9A 5LB7B 1UX5A 1WLXA 4IE0A 4DV3T 5LP6E 1NENA 5C8YE 4ERRA 5ABGA 3AA1B 2BBHA 3ZC1A 4HFHA 3VRAA 4ILCA 1IZNB 4U33A 2XASB 3TLSA 2BG9C 2H7OA 5LBMA 4B6XA 3B5MA 3RIUC 2B76A 3ABVA 3JCFA 1SUMB 1KF6A 3ZPOA 1YW0A 2BKNA 2DNXA 5J0ZA 4OFZA 5HAXA 1MNEA 4DR6T 5AQOB 4JYAT 2E2AA 5FXZA 2XHEB 2W00A 2CPTA 2UXXB 2Y48B 5BMVE 5KMGP 2X66A 2F4VT 3ZCJA 2NW7A 3CQGB 3BQLA 3AE1A 3N9MA 1ZP0A 2V6XA 2XQ7A 1S94A 5FVLA 4IHJE 1N34T 4EIWA 4I50E 4H9OC 4J2CA 2X9YA 3EI0A 4KHPT 2A2FX 4A97A 2W2UA 5LNKA 4I55E 4JI5T 3CIRA 3AE7A 4TWDA 3ZMUB 3TLUA 3P4PA 3ZN1B 4PW8A 3OPCA 2ODUA 4UVCB 2DHRA 2E9XB 3M3ZB 3MACA 2D0TA 4QHOA 5CGMA 2KZ7B 4UVBB 2CXFA 5JRCB 4EOZB 5CA0E 4PK4A 2LSKA 3AXJA 2DWGA 1MIWA 2WWVA 2VL0A 3N2KE 1YD8G 2I6HA 2D5UA 3LK2B 5HXCA 1HFAA 1XNQT 2DWKA 3OYZA 1BR1A 3UUBA 3CX6B 4CZZB 4PFOA 2LHRA 4IT4A 4YTPA 4BJNA 3Q5DA 3AVRA 1E2AA 2H88A 4O2BE 3LDQB 3RPUA 2WMNA 1VCTA 3VR8A 1OEDA 3PU3A 4DV0T 4GK5E 2H89A 4GKJT 2VASA 5C3JA 1OEDE 5JR9B 4LFCT 2XM1A 4DUZT 4YFSA 2EHOD 2XJ7A 1VCSA 1HR0T 4LF8T 4F8HA 2MOZA 2WSSV 3AE6A 4YTNA 4JEHB 3ZKRA 2YDSA 4KHZF 3RKOA 5CB4E 3FB2A 3ANWB 5ABFA 2LE8A 2Z6EA 2BG9E 3A8YC 3JADA 4YT0A 3NZQA 3TKLB 2LKGA 4QXCB 2M67A 3P50A 3RC8A 3UUXB 3L3PA 1FEWA 2NR4A 3L09A 4P09A 3PUWF 4K0KT 2P9BA 2W61A 5LMNT 2IHR1 2L9QA 3HKDE 3KBTA 1HG5A 5AQUB 4DNDA 2C5IT 4GKKT 3RX6A 3K8PC 4YHHT 3N2GE 1LVFA 2LSIA 4C90A 4HWFA 3LG7A 3C50A 1MMNA 3CPZA 2YK0A 1IBMT 4DR3T 1G73A 2IMLA 1KNPA 3W15B 2N9DA 3ZMSB 1FJGT 4MLKA 4UELA 1J5WA 4COFA 2VL8A 4WBOA 2K48A 4YHJA 4H63V 1WR0A 1HG2A 3FZHB 5JTGA 4GIWA 5JREA 3L8RA 4NIQA 4QX8B 1QSDA 3A5XA 1IBLT 3FHNA 3EVYA 5FY1A 2V7JA 1LVKA 5HWYA 2I59A 3Q9DA 2JIWA 1XNRT 2WZIA 2K5BB 1FIOA 4TUYE 3AVSA 2YKSA 1KNZA 1EZ3A 2UUBT 1LRZA 4BJMA 3MXZA 4PK5A 1HNWT 4JI8T 3I9WA 2KINB 3FZMB 3NRYA 2V5DA 3KVBA 3E0ZA 4CXWA 4EEBA 4I0UA 2VVSA 3I0OA 3M65A 5L3DB 4CN6A 1T72A 2E9XA 3OVUA 3GN5A 3QK6A 4X1IE 2FBWA 4YSYA 4GOUA 2Y6XA 3CX7B 4U7YA 4JV5T 4HWDA 3AEDA 3PDYA 3RF1A 5LHHB 2IAKA 2CM0A 3DTOA 5JDFA 2UXDT 4PJJA 5JH7E 3AA0B 4CXXA 4EAHA 1OWAA 2CLYB 5HXHA 3UU5A 4WW0A 4JI1T 2YN6A 2HN2A 2KWIB 2KWHA 3NRXA 2BZBA 2WS3A 4WNKA 3HKCE 3WAJA 3ONJA 4IDPA 2AE9A 3RYIE 3G06A 2IW5B 3EUHA 3FXEB 3D0TA 5AQTB 3KV5A 4IE4A 2FJBA 2MYSA 4EB6E 3UT5E 4LMKA 2E9XD 4KBMB 4DBQA 2LSYA 5HEUA 4Q25A 3QOFA 3AXJB 1B7TA 5JR9A 1YQ4A 1MIVA 4LMJA 2WZHA 5HEOA 4Z8XA 5LG3A 1N32T 1US7B 4KMCA 1T98A 1Z8UA 2BDEA 4JI6T 3ANWA 2NW9A 1YQ3A 3RI5A 1V9DA 2V7LA 2X0YA 2XQ6A 2WBLA 4CI2B 4HWCA 4PK6A 4MHCA 2UXCT 1GQEA 2K9AA 3E08A 2D0UA 4QWNB 4JI0T 4YY3T 2UUCT 2VKHA 2CXDA 1IBKT 3F31A 1E7PA 1HX1B 5AQMB 3JC6D 1HNXT 4DR4T 4DV4T 2JMHA 2BBJA 4YSZA 3VR9A 5EK4A 5IYZE 4ZI2C 1SE7A 4IE7A 1VOMA 4UXNB 2CHOA 3EAMA 4ZZCA 5HWXA 3UU4A 3Q5EA 4HTEA 4ZS3A 3SRZA 1D1AA 3P4RA 3UQ7A 4AKHA 3N9NA 2NTXA 3GMIA 5FYMA 5L3BB 2LHNA 1LKXA 4GYSA 3WAKA 1KEYA 4X65T 3HA4A 3NBXX 3FBLA 1ZEEA 3PV0F 3RHWA 4DUYT 2CE7A 2ACZA 5H6RB 4CI1B 1OEDC 4K0UA 3AEBA 4P0BA 5M4YA 4AKLA 3CKDA 5HEGA 3U78A 3T1HT 5L2LA 5DQVA 3SOLA 3F57A 2XAJB 3VU7H 5F3JA 4EZHA 4Z91A 3MZKB 5LYJE 2CBJA 3A7MA 4ZI3D 4DBRA 2L8KA 1UUSA 3RLFF 3P7IA 1J1JA 2X51A 3RYFE 1W0BA 3RKGA 3C4WA 2ODVA 2UU9T 4HFDA 1HX8A 2X9WA 4O4HE 4ZI7E 3B57A 4AISA 5ABHA 2CXLA 2E8IA 3AA6B 2LRLA 3PUXF 1IJ5A 4EYYR 3H37A 2JPFA 5FP3A 2M6IA 4H9SE 5L3FB 3T8OA 5L4EA 1XDPA 1MNDA 2OLTA 2LRKA 2VWAA 4AKIA 3HI2A 2XQ5A 2ZM2A 4ZXLA 5LMUT 3LSVA 4DV1T 3F2EA 4PJMA 3I0QA 4QXBB 4OYJA 4EEDA 4HFVA 1MMGA 3K3OA 3KV4A 2WCAA 4X62T 3GN5B 3RRWA 4LF5T 2NWBA 4A56A 2YDRA 2KMFA 2WU2A 3KV9A 2WM9A 2NP9A 4U2YA 4ZZBA 4ZOLE 2RP4A 3ZYMA 4NUUA 3X1DA 2YEVC 5AQLB 5F8PA 2OV9A 4UV9B 4X5TA 4TN7B 4H63H 4JBWF 3R84B 3AE5A 2QA7A 4F6RC 4ASKA 3MA9A 4Z90A 3RIAA 4AKGA 4P1NA 2CHNA 3WI3A 2PJQA 4TNVA 1T7SA 2E9XC 1KK7A 1E1HB 3FXDB 5AQNB 2UXBT 3ZMTB 2QYWA 4KUMB 3OJAA 4QX7B 2XQ3A 1Z0PA 3O9XA 3K3NA 3QUJA 1O3XA 4KI0F 2V7KA 3NVOA 5CA1E 5JDLA 4ZI2D 2MBGA 2J47A 3ZMZB 3BK9A 2X9HA 2V26A 2HPLA 4CI3B 2LEHA 4IDZA 5LBQB 2K24A 4B3TT 4X1YE 3RIUA 2DCFA 1VRBA 5LHGB 1UX4A 4JLEA 1ZKEA 1UK5A 3IEEA 2H7VC 1S35A 4DV7T 3ZT6A 3JC6C 5JR9C 4NPPA 3ZC0A 4O8SA 1FMVA 3MK7C 4V1Av 5CJ5A 4EZ4A 2W0GA 4L0RA 3O1HA 2LJLA 4TX5A 3N9PA 3ZN0B 1XMQT 4DMWA 2CEAA 3ZCIA 4JI3T 1UGOA 2XQ8A 3ZYKA 1DU2A 2PFVA 3B13A 1MMAA 2OA5A 3K3QC 4B3MT 3UTKA 5AQQB 3EDVA 5AQFB 4PFPA 5JQGE 1WFDA 3ESLA 2VB6A 2PBIA 2W66A 2BKOA 3PTRB 2XQ4A 1X79A 4GYRA 4NXMT 3QB5K 4DO0A 4HE8A 2YOEA 1X9BA 1J5ET 2CRBA 4YLHA 2D9DA 2WDVA 2XSBA 2KXPB 4AQYT 4ZI3C 4O2AE 4ILAA 3QC9A 2E5VA 3IA3A 2LOPA 5JDNA 1SA0E 2V6YB 4JEUB 3SS1A 3PU8A 5AQPB 2KT9A 4EV6A 3HKEE 5ABEA 2RA1A 4OYKA 4TWFA 4DV2T 2Q9QB 5C2TA 1AJ3A 3CWZB 1XMOT 2BVMA 2LKHA 1D0XA 1H7CA 4LF7T 2ES0A 2W67A 1HF8A 2V1DB 3P4SA 3LBXB 4TNWA 3AE4A 5F5WA 3VKHA 2RPAA 1FMWA 4TWHA 2VKDA 4AXPA 5L47A 3AAEB 2FJAA 2IDOB 3CQCB 2J4GA 2L3LA 5JDHA 5FY0A 2A3DA 2M6BA 2A9UA 5LJNA 1MMDA 1R8IA 3CK6A 2D2SA 4IL9A 4U31A 5FKYA 5LGTB 4A98A 1CUNA 1XWMA 3U3IA 3NZPA 3RGLA 3O1JA 4JI7T 2NTYA 4ISSA 4H9NC 4NUVA 2XUEA 2CCQA 2B1EA 2JQHA 2YU2A 1MIYA 2JQQA 3PUVF 4H9PC 2VK9A 3J9X1 1XDOA 3C4XA 2W4XA 3CVRA 2EHOB 2XQAA 3O1IA 1N36T 3IBPA 3RYCE 2UUAT 1WYCA 3ZLIA 1W0AA 4HN9A 3K1SA 5BR8T 4GK0E 2CLYC 5AQHB 2WB5A 3PJAA 3AB3B 4UF0B 3VRBA 2XTLA 3ZJ1A 3JAFA 1G8XA 5E0OA 2H3RA 3GWHA 3Q5XA 1Y01A 2XAGB 2VKJA 1YKHB 3ONLC 4QH4A 5GONE 3P4WA 2CWYA 1SHZC 3AE8A 3ZJ2A 3EDUA 3FBZA 2SPCA 5JVDE 3PUSA 1KNRA 2A72A 3P4QA 4YXDA 3C4ZA 2ZMAA 4LF4T 1OXZA 3LK3B 3P8CD 2AXDS 1U5PA 5ETWA 3UU6A 2K3WA 2FJDA 2XQ9A 3IHRA 4WBNE 3AECA 4HGAA 2BG9B 5FL1A 3ETUA 5EZYE 2IC9A 2PG8A 2ACXA 4NXNT 2X9XA 3C98B 3I1AA 2BS2A 2WMOA 2CWOA 3UQ4A 2XAQB 3AE2A 4YJ2E 2V7IA 3UU8A 3NKZA 1WCRA 3AE9A 3IF8B 4XAXB 5LG4A 2WDRA 3AEGA 3HL6A 1D1BA 4JUYA 3I9YA 5ADXL 4WYVA 2V8SV 4OX9T 2V6YA 5FVKA 5HXRA 3SFEA 1JNRA
chains in the Genus database with same CATH topology
5AQOB 5AQNB 5AQGB 3M3ZB 4HWCA 1HX1B 5AQMB 1I6ZA 3FZKB 4HWDA 1M7KA 5AQRB 1UK5A 3A8YC 5AQLB 5AQUB 3FZFB 4HWIB 5AQQB 1M62A 1T7SA 3LDQB 3FZHB 5AQSB 5AQFB 5AQPB 5AQVB 2D9DA 3FZLB 5AQJB 3FZMB 5AQIB 5AQHB 5AQTB 5AQKB 1UGOA 4HWFA 4HWHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AQO B;  5AQN B;  5AQG B;  3M3Z B;  4HWC A;  1HX1 B;  5AQM B;  1I6Z A;  3FZK B;  4HWD A;  1M7K A;  5AQR B;  1UK5 A;  3A8Y C;  5AQL B;  5AQU B;  3FZF B;  4HWI B;  5AQQ B;  1M62 A;  1T7S A;  3LDQ B;  3FZH B;  5AQS B;  5AQF B;  5AQP B;  5AQV B;  2D9D A;  3FZL B;  5AQJ B;  3FZM B;  5AQI B;  5AQH B;  5AQT B;  5AQK B;  1UGO A;  4HWF A;  4HWH A; 
#chains in the Genus database with same CATH topology
 4IGU A;  3KDS E;  3N2O A;  5KXJ A;  2LLY A;  2Q9Q A;  3BQI A;  4KX6 A;  3TLV A;  1NWM X;  2CBI A;  4LML A;  4ILU A;  3ZT5 A;  3CML A;  1HNZ T;  1IJ6 A;  3LBX A;  4PAG A;  4DID B;  2LT3 A;  3N9L A;  4XZC A;  5HEH A;  1BR4 A;  4P0A A;  2YU1 A;  2VVN A;  1L0V A;  5DJQ C;  4B3R T;  2ZLY A;  4B3S T;  5AQV B;  4ILB A;  3PUG A;  5HCJ A;  5LXT E;  4AKR B;  4HEA A;  4H9Q C;  4UVA B;  3TLT A;  3S4U A;  2KSR A;  4ZEY A;  5L3G B;  5EK2 A;  3ZT7 A;  3KFW X;  4IL4 A;  4G2A A;  2NW8 A;  3UFG A;  3UUM A;  3GA8 A;  2UXN B;  5IUX A;  2X68 A;  2XAH B;  4U7I A;  4JI4 T;  2CMR A;  4HFC A;  3RQW A;  2Q9Q D;  4IDN A;  5AQG B;  4IDQ A;  4IE5 A;  1I6Z A;  1UCU A;  1BR2 A;  4IRE A;  2DI4 A;  2JMK A;  4TV9 E;  2EHO A;  3ETV A;  4DVD A;  2E5L T;  2V7M A;  5LJM A;  3PUQ A;  4QKN A;  3BQK A;  2WU5 A;  4CQI A;  2LM2 A;  3PUA A;  5J1G A;  3ZMV B;  1D0Z A;  5AFU L;  1T8B A;  1YKE B;  3RH3 A;  4E7Z A;  3CQX C;  4UF0 A;  4BAY B;  2FUP A;  2PTF A;  3PUY F;  4U72 A;  4AIU A;  5FXV A;  3VKG A;  1YXR A;  1N33 T;  1HCI A;  2XM2 A;  3OKQ A;  4DR2 T;  4LFB T;  4U2Z A;  3V5S A;  2MPK A;  5FXW A;  3LK4 2;  5EK3 A;  3R6N A;  2XY8 B;  2VQE T;  2WAU A;  4AQF A;  3LFM A;  2XAF B;  3O4X E;  4HFE A;  2WY2 A;  2CA5 A;  4YJ3 E;  4ADZ A;  3UUN A;  3L39 A;  2XSA A;  2I0M A;  2BKP A;  1W9R A;  4MFR A;  4PJN A;  1XZY A;  4BA9 A;  5H6Q B;  5A1L A;  4FJO A;  1M62 A;  2X0H A;  3AEF A;  4UIG A;  5AQS B;  5LHI B;  1WYB A;  2BG9 A;  5LCY A;  3JAE A;  4L5G A;  3NWI A;  3RRC A;  3Q5W A;  3Q2M A;  3RIF A;  2IC6 A;  3E22 E;  2WDQ A;  2KLQ A;  4ANJ A;  3RYH E;  1IAP A;  1UUR A;  2XZE A;  4LF6 T;  2LM9 A;  1ZOY A;  2IIU A;  1HS7 A;  4U74 A;  3FZK B;  1W09 A;  1NAF A;  4H9R C;  4X20 E;  3LJC A;  4DV5 T;  4OK0 A;  2VUR A;  3AEE A;  3UUL A;  5L3C B;  2YIN A;  4HFI A;  4UEM A;  3ZST A;  2ZM8 A;  3ONX A;  2C5J A;  2ZM0 A;  3ZSS A;  4UR9 A;  5HXE A;  3EHZ A;  4QH1 A;  2W63 A;  2MAW A;  2FJE A;  5FNV E;  3SFD A;  1NEK A;  2QRX A;  3RQU A;  2V5C A;  4QXH B;  5FMN A;  2N2N A;  4UV8 B;  1KFY A;  2C0S A;  2LSJ A;  5LGU B;  4MBQ A;  2YDQ A;  4YSX A;  2G0U A;  3N9Q A;  4DV6 T;  4C91 A;  5IHY A;  3KVA A;  4IST A;  2ZM6 T;  4E7S A;  2X67 A;  4ZHQ E;  2LSG A;  2W62 A;  5FL0 A;  5HYA A;  5LOV E;  4CN4 A;  1ZHC A;  3HKB E;  5FY7 A;  5LA6 E;  4DMV A;  1Y64 B;  2IUB A;  4AI6 A;  5HEJ A;  3C51 A;  3QNU A;  4XBF B;  3AE3 A;  3DP7 A;  1D1C A;  1HTJ F;  4DR1 T;  5DAB A;  4ZS2 A;  5JRC A;  2HH7 A;  2WP9 A;  1QLB A;  4CXY A;  4LFA T;  3MKD A;  3T1Y T;  2MTQ A;  1I94 T;  3CX8 B;  3ZEF B;  4EGW A;  4TZ4 C;  2DLR A;  5IWA T;  4EYU A;  3PUZ F;  2KND A;  5JDM A;  3FZL B;  5AQJ B;  4EXT A;  5AQI B;  4DR5 T;  3V5U A;  1D0Y A;  5AQK B;  5AQR B;  4CN1 A;  2BS3 A;  1CHU A;  4HFB A;  5KDM C;  2VKO A;  3AAI A;  1ZV4 X;  4TV8 E;  3PJA J;  1JNZ A;  3FZF B;  2Q9Q C;  3N5L A;  3AA7 B;  2R6G F;  5J2T E;  4L9I A;  3N9O A;  2LOS A;  3OBV E;  2X0L B;  5HCM A;  3UU3 A;  2QVA A;  4X1K E;  5DQW A;  3KIN B;  4I4T E;  4WZX A;  4OHF A;  2NOX A;  3HR0 A;  4N78 D;  5KX5 E;  4KP3 C;  4HKA A;  3PUR A;  1QUU A;  2XPK A;  5FXX A;  2BVL A;  4IIJ E;  3AAA B;  3J7Y q;  3VHL A;  1M7K A;  3KV6 A;  5JDG A;  4PJL A;  4MAL A;  4DR7 T;  3AEA A;  4JI2 T;  4PNI A;  2DL1 A;  2JRK A;  4A5X A;  2JQ9 A;  3ZYL A;  4X64 T;  2JJ9 A;  4HWH A;  2N1G A;  3UFE A;  4U3C A;  3TLW A;  2HN1 A;  5TAO A;  2C5K T;  5L3E B;  3RC3 A;  5L4H A;  4QH5 A;  2BS4 A;  1OED B;  2JQK A;  4HWI B;  4LF9 T;  1U4Q A;  4IDO A;  4FI5 A;  5LGN B;  3QB5 A;  4M1P A;  1WR6 A;  2EHO C;  2HHH T;  3EAB A;  4O4J E;  2VQF T;  3PE0 A;  3KBU A;  4YTM A;  3MJX A;  3C64 A;  4O4L E;  5CFB A;  5HXS A;  4G63 A;  5ABF B;  5J2U E;  4AQG A;  2J1D G;  2HPJ A;  2QGS A;  2XQY A;  4X66 T;  3OTO T;  2WWU A;  2WQY A;  4I43 B;  3H3M A;  2Y8D A;  4IE6 A;  1BR0 A;  2J62 A;  3DJB A;  1WRD A;  3OYX A;  4AQF C;  3H3A A;  3SWH A;  4O4I E;  5JDQ A;  2GK9 A;  5LB7 B;  1UX5 A;  1WLX A;  4IE0 A;  4DV3 T;  5LP6 E;  1NEN A;  5C8Y E;  4ERR A;  5ABG A;  3AA1 B;  2BBH A;  3ZC1 A;  4HFH A;  3VRA A;  4ILC A;  1IZN B;  4U33 A;  2XAS B;  3TLS A;  2BG9 C;  2H7O A;  5LBM A;  4B6X A;  3B5M A;  3RIU C;  2B76 A;  3ABV A;  3JCF A;  1SUM B;  1KF6 A;  3ZPO A;  1YW0 A;  2BKN A;  2DNX A;  5J0Z A;  4OFZ A;  5HAX A;  1MNE A;  4DR6 T;  5AQO B;  4JYA T;  2E2A A;  5FXZ A;  2XHE B;  2W00 A;  2CPT A;  2UXX B;  2Y48 B;  5BMV E;  5KMG P;  2X66 A;  2F4V T;  3ZCJ A;  2NW7 A;  3CQG B;  3BQL A;  3AE1 A;  3N9M A;  1ZP0 A;  2V6X A;  2XQ7 A;  1S94 A;  5FVL A;  4IHJ E;  1N34 T;  4EIW A;  4I50 E;  4H9O C;  4J2C A;  2X9Y A;  3EI0 A;  4KHP T;  2A2F X;  4A97 A;  2W2U A;  5LNK A;  4I55 E;  4JI5 T;  3CIR A;  3AE7 A;  4TWD A;  3ZMU B;  3TLU A;  3P4P A;  3ZN1 B;  4PW8 A;  3OPC A;  2ODU A;  4UVC B;  2DHR A;  2E9X B;  3M3Z B;  3MAC A;  2D0T A;  4QHO A;  5CGM A;  2KZ7 B;  4UVB B;  2CXF A;  5JRC B;  4EOZ B;  5CA0 E;  4PK4 A;  2LSK A;  3AXJ A;  2DWG A;  1MIW A;  2WWV A;  2VL0 A;  3N2K E;  1YD8 G;  2I6H A;  2D5U A;  3LK2 B;  5HXC A;  1HFA A;  1XNQ T;  2DWK A;  3OYZ A;  1BR1 A;  3UUB A;  3CX6 B;  4CZZ B;  4PFO A;  2LHR A;  4IT4 A;  4YTP A;  4BJN A;  3Q5D A;  3AVR A;  1E2A A;  2H88 A;  4O2B E;  3LDQ B;  3RPU A;  2WMN A;  1VCT A;  3VR8 A;  1OED A;  3PU3 A;  4DV0 T;  4GK5 E;  2H89 A;  4GKJ T;  2VAS A;  5C3J A;  1OED E;  5JR9 B;  4LFC T;  2XM1 A;  4DUZ T;  4YFS A;  2EHO D;  2XJ7 A;  1VCS A;  1HR0 T;  4LF8 T;  4F8H A;  2MOZ A;  2WSS V;  3AE6 A;  4YTN A;  4JEH B;  3ZKR A;  2YDS A;  4KHZ F;  3RKO A;  5CB4 E;  3FB2 A;  3ANW B;  5ABF A;  2LE8 A;  2Z6E A;  2BG9 E;  3A8Y C;  3JAD A;  4YT0 A;  3NZQ A;  3TKL B;  2LKG A;  4QXC B;  2M67 A;  3P50 A;  3RC8 A;  3UUX B;  3L3P A;  1FEW A;  2NR4 A;  3L09 A;  4P09 A;  3PUW F;  4K0K T;  2P9B A;  2W61 A;  5LMN T;  2IHR 1;  2L9Q A;  3HKD E;  3KBT A;  1HG5 A;  5AQU B;  4DND A;  2C5I T;  4GKK T;  3RX6 A;  3K8P C;  4YHH T;  3N2G E;  1LVF A;  2LSI A;  4C90 A;  4HWF A;  3LG7 A;  3C50 A;  1MMN A;  3CPZ A;  2YK0 A;  1IBM T;  4DR3 T;  1G73 A;  2IML A;  1KNP A;  3W15 B;  2N9D A;  3ZMS B;  1FJG T;  4MLK A;  4UEL A;  1J5W A;  4COF A;  2VL8 A;  4WBO A;  2K48 A;  4YHJ A;  4H63 V;  1WR0 A;  1HG2 A;  3FZH B;  5JTG A;  4GIW A;  5JRE A;  3L8R A;  4NIQ A;  4QX8 B;  1QSD A;  3A5X A;  1IBL T;  3FHN A;  3EVY A;  5FY1 A;  2V7J A;  1LVK A;  5HWY A;  2I59 A;  3Q9D A;  2JIW A;  1XNR T;  2WZI A;  2K5B B;  1FIO A;  4TUY E;  3AVS A;  2YKS A;  1KNZ A;  1EZ3 A;  2UUB T;  1LRZ A;  4BJM A;  3MXZ A;  4PK5 A;  1HNW T;  4JI8 T;  3I9W A;  2KIN B;  3FZM B;  3NRY A;  2V5D A;  3KVB A;  3E0Z A;  4CXW A;  4EEB A;  4I0U A;  2VVS A;  3I0O A;  3M65 A;  5L3D B;  4CN6 A;  1T72 A;  2E9X A;  3OVU A;  3GN5 A;  3QK6 A;  4X1I E;  2FBW A;  4YSY A;  4GOU A;  2Y6X A;  3CX7 B;  4U7Y A;  4JV5 T;  4HWD A;  3AED A;  3PDY A;  3RF1 A;  5LHH B;  2IAK A;  2CM0 A;  3DTO A;  5JDF A;  2UXD T;  4PJJ A;  5JH7 E;  3AA0 B;  4CXX A;  4EAH A;  1OWA A;  2CLY B;  5HXH A;  3UU5 A;  4WW0 A;  4JI1 T;  2YN6 A;  2HN2 A;  2KWI B;  2KWH A;  3NRX A;  2BZB A;  2WS3 A;  4WNK A;  3HKC E;  3WAJ A;  3ONJ A;  4IDP A;  2AE9 A;  3RYI E;  3G06 A;  2IW5 B;  3EUH A;  3FXE B;  3D0T A;  5AQT B;  3KV5 A;  4IE4 A;  2FJB A;  2MYS A;  4EB6 E;  3UT5 E;  4LMK A;  2E9X D;  4KBM B;  4DBQ A;  2LSY A;  5HEU A;  4Q25 A;  3QOF A;  3AXJ B;  1B7T A;  5JR9 A;  1YQ4 A;  1MIV A;  4LMJ A;  2WZH A;  5HEO A;  4Z8X A;  5LG3 A;  1N32 T;  1US7 B;  4KMC A;  1T98 A;  1Z8U A;  2BDE A;  4JI6 T;  3ANW A;  2NW9 A;  1YQ3 A;  3RI5 A;  1V9D A;  2V7L A;  2X0Y A;  2XQ6 A;  2WBL A;  4CI2 B;  4HWC A;  4PK6 A;  4MHC A;  2UXC T;  1GQE A;  2K9A A;  3E08 A;  2D0U A;  4QWN B;  4JI0 T;  4YY3 T;  2UUC T;  2VKH A;  2CXD A;  1IBK T;  3F31 A;  1E7P A;  1HX1 B;  5AQM B;  3JC6 D;  1HNX T;  4DR4 T;  4DV4 T;  2JMH A;  2BBJ A;  4YSZ A;  3VR9 A;  5EK4 A;  5IYZ E;  4ZI2 C;  1SE7 A;  4IE7 A;  1VOM A;  4UXN B;  2CHO A;  3EAM A;  4ZZC A;  5HWX A;  3UU4 A;  3Q5E A;  4HTE A;  4ZS3 A;  3SRZ A;  1D1A A;  3P4R A;  3UQ7 A;  4AKH A;  3N9N A;  2NTX A;  3GMI A;  5FYM A;  5L3B B;  2LHN A;  1LKX A;  4GYS A;  3WAK A;  1KEY A;  4X65 T;  3HA4 A;  3NBX X;  3FBL A;  1ZEE A;  3PV0 F;  3RHW A;  4DUY T;  2CE7 A;  2ACZ A;  5H6R B;  4CI1 B;  1OED C;  4K0U A;  3AEB A;  4P0B A;  5M4Y A;  4AKL A;  3CKD A;  5HEG A;  3U78 A;  3T1H T;  5L2L A;  5DQV A;  3SOL A;  3F57 A;  2XAJ B;  3VU7 H;  5F3J A;  4EZH A;  4Z91 A;  3MZK B;  5LYJ E;  2CBJ A;  3A7M A;  4ZI3 D;  4DBR A;  2L8K A;  1UUS A;  3RLF F;  3P7I A;  1J1J A;  2X51 A;  3RYF E;  1W0B A;  3RKG A;  3C4W A;  2ODV A;  2UU9 T;  4HFD A;  1HX8 A;  2X9W A;  4O4H E;  4ZI7 E;  3B57 A;  4AIS A;  5ABH A;  2CXL A;  2E8I A;  3AA6 B;  2LRL A;  3PUX F;  1IJ5 A;  4EYY R;  3H37 A;  2JPF A;  5FP3 A;  2M6I A;  4H9S E;  5L3F B;  3T8O A;  5L4E A;  1XDP A;  1MND A;  2OLT A;  2LRK A;  2VWA A;  4AKI A;  3HI2 A;  2XQ5 A;  2ZM2 A;  4ZXL A;  5LMU T;  3LSV A;  4DV1 T;  3F2E A;  4PJM A;  3I0Q A;  4QXB B;  4OYJ A;  4EED A;  4HFV A;  1MMG A;  3K3O A;  3KV4 A;  2WCA A;  4X62 T;  3GN5 B;  3RRW A;  4LF5 T;  2NWB A;  4A56 A;  2YDR A;  2KMF A;  2WU2 A;  3KV9 A;  2WM9 A;  2NP9 A;  4U2Y A;  4ZZB A;  4ZOL E;  2RP4 A;  3ZYM A;  4NUU A;  3X1D A;  2YEV C;  5AQL B;  5F8P A;  2OV9 A;  4UV9 B;  4X5T A;  4TN7 B;  4H63 H;  4JBW F;  3R84 B;  3AE5 A;  2QA7 A;  4F6R C;  4ASK A;  3MA9 A;  4Z90 A;  3RIA A;  4AKG A;  4P1N A;  2CHN A;  3WI3 A;  2PJQ A;  4TNV A;  1T7S A;  2E9X C;  1KK7 A;  1E1H B;  3FXD B;  5AQN B;  2UXB T;  3ZMT B;  2QYW A;  4KUM B;  3OJA A;  4QX7 B;  2XQ3 A;  1Z0P A;  3O9X A;  3K3N A;  3QUJ A;  1O3X A;  4KI0 F;  2V7K A;  3NVO A;  5CA1 E;  5JDL A;  4ZI2 D;  2MBG A;  2J47 A;  3ZMZ B;  3BK9 A;  2X9H A;  2V26 A;  2HPL A;  4CI3 B;  2LEH A;  4IDZ A;  5LBQ B;  2K24 A;  4B3T T;  4X1Y E;  3RIU A;  2DCF A;  1VRB A;  5LHG B;  1UX4 A;  4JLE A;  1ZKE A;  1UK5 A;  3IEE A;  2H7V C;  1S35 A;  4DV7 T;  3ZT6 A;  3JC6 C;  5JR9 C;  4NPP A;  3ZC0 A;  4O8S A;  1FMV A;  3MK7 C;  4V1A v;  5CJ5 A;  4EZ4 A;  2W0G A;  4L0R A;  3O1H A;  2LJL A;  4TX5 A;  3N9P A;  3ZN0 B;  1XMQ T;  4DMW A;  2CEA A;  3ZCI A;  4JI3 T;  1UGO A;  2XQ8 A;  3ZYK A;  1DU2 A;  2PFV A;  3B13 A;  1MMA A;  2OA5 A;  3K3Q C;  4B3M T;  3UTK A;  5AQQ B;  3EDV A;  5AQF B;  4PFP A;  5JQG E;  1WFD A;  3ESL A;  2VB6 A;  2PBI A;  2W66 A;  2BKO A;  3PTR B;  2XQ4 A;  1X79 A;  4GYR A;  4NXM T;  3QB5 K;  4DO0 A;  4HE8 A;  2YOE A;  1X9B A;  1J5E T;  2CRB A;  4YLH A;  2D9D A;  2WDV A;  2XSB A;  2KXP B;  4AQY T;  4ZI3 C;  4O2A E;  4ILA A;  3QC9 A;  2E5V A;  3IA3 A;  2LOP A;  5JDN A;  1SA0 E;  2V6Y B;  4JEU B;  3SS1 A;  3PU8 A;  5AQP B;  2KT9 A;  4EV6 A;  3HKE E;  5ABE A;  2RA1 A;  4OYK A;  4TWF A;  4DV2 T;  2Q9Q B;  5C2T A;  1AJ3 A;  3CWZ B;  1XMO T;  2BVM A;  2LKH A;  1D0X A;  1H7C A;  4LF7 T;  2ES0 A;  2W67 A;  1HF8 A;  2V1D B;  3P4S A;  3LBX B;  4TNW A;  3AE4 A;  5F5W A;  3VKH A;  2RPA A;  1FMW A;  4TWH A;  2VKD A;  4AXP A;  5L47 A;  3AAE B;  2FJA A;  2IDO B;  3CQC B;  2J4G A;  2L3L A;  5JDH A;  5FY0 A;  2A3D A;  2M6B A;  2A9U A;  5LJN A;  1MMD A;  1R8I A;  3CK6 A;  2D2S A;  4IL9 A;  4U31 A;  5FKY A;  5LGT B;  4A98 A;  1CUN A;  1XWM A;  3U3I A;  3NZP A;  3RGL A;  3O1J A;  4JI7 T;  2NTY A;  4ISS A;  4H9N C;  4NUV A;  2XUE A;  2CCQ A;  2B1E A;  2JQH A;  2YU2 A;  1MIY A;  2JQQ A;  3PUV F;  4H9P C;  2VK9 A;  3J9X 1;  1XDO A;  3C4X A;  2W4X A;  3CVR A;  2EHO B;  2XQA A;  3O1I A;  1N36 T;  3IBP A;  3RYC E;  2UUA T;  1WYC A;  3ZLI A;  1W0A A;  4HN9 A;  3K1S A;  5BR8 T;  4GK0 E;  2CLY C;  5AQH B;  2WB5 A;  3PJA A;  3AB3 B;  4UF0 B;  3VRB A;  2XTL A;  3ZJ1 A;  3JAF A;  1G8X A;  5E0O A;  2H3R A;  3GWH A;  3Q5X A;  1Y01 A;  2XAG B;  2VKJ A;  1YKH B;  3ONL C;  4QH4 A;  5GON E;  3P4W A;  2CWY A;  1SHZ C;  3AE8 A;  3ZJ2 A;  3EDU A;  3FBZ A;  2SPC A;  5JVD E;  3PUS A;  1KNR A;  2A72 A;  3P4Q A;  4YXD A;  3C4Z A;  2ZMA A;  4LF4 T;  1OXZ A;  3LK3 B;  3P8C D;  2AXD S;  1U5P A;  5ETW A;  3UU6 A;  2K3W A;  2FJD A;  2XQ9 A;  3IHR A;  4WBN E;  3AEC A;  4HGA A;  2BG9 B;  5FL1 A;  3ETU A;  5EZY E;  2IC9 A;  2PG8 A;  2ACX A;  4NXN T;  2X9X A;  3C98 B;  3I1A A;  2BS2 A;  2WMO A;  2CWO A;  3UQ4 A;  2XAQ B;  3AE2 A;  4YJ2 E;  2V7I A;  3UU8 A;  3NKZ A;  1WCR A;  3AE9 A;  3IF8 B;  4XAX B;  5LG4 A;  2WDR A;  3AEG A;  3HL6 A;  1D1B A;  4JUY A;  3I9Y A;  5ADX L;  4WYV A;  2V8S V;  4OX9 T;  2V6Y A;  5FVK A;  5HXR A;  3SFE A;  1JNR A; 
#chains in the Genus database with same CATH homology
 5AQO B;  5AQN B;  5AQG B;  3M3Z B;  4HWC A;  1HX1 B;  5AQM B;  1I6Z A;  3FZK B;  4HWD A;  1M7K A;  5AQR B;  1UK5 A;  3A8Y C;  5AQL B;  5AQU B;  3FZF B;  4HWI B;  5AQQ B;  1M62 A;  1T7S A;  3LDQ B;  3FZH B;  5AQS B;  5AQF B;  5AQP B;  5AQV B;  2D9D A;  3FZL B;  5AQJ B;  3FZM B;  5AQI B;  5AQH B;  5AQT B;  5AQK B;  1UGO A;  4HWF A;  4HWH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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