5AQGB

Fragment-based screening of hsp70 sheds light on the functional role of atp-binding site residues
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
113
structure length
113
Chain Sequence
GSNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
pubmed doi rcsb
molecule tags Chaperone
source organism Homo sapiens
molecule keywords HEAT SHOCK COGNATE 71 KDA PROTEIN
total genus 44
structure length 113
sequence length 113
chains with identical sequence D, F
ec nomenclature
pdb deposition date 2015-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02179 BAG BAG domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.58.120 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase; Chain G, domain 1 BAG domain 5aqgB00
3M3ZB 5AQIB 1UGOA 5AQNB 5AQTB 3FZFB 5AQHB 1M7KA 5AQLB 5AQRB 2D9DA 5AQVB 5AQSB 5AQQB 3FZHB 5AQOB 5AQUB 5AQFB 3A8YC 4HWCA 5AQKB 4HWFA 3LDQB 4HWIB 5AQPB 4HWHA 1UK5A 1HX1B 4HWDA 1T7SA 5AQJB 3FZMB 1I6ZA 1M62A 3FZLB 5AQGB 5AQMB 3FZKB
chains in the Genus database with same CATH superfamily
2WU2A 2AXDS 4LMKA 4UVCB 4H9QC 5L4EA 4K0UA 3AEEA 4A56A 4PJJA 3N9NA 3I9YA 4JI6T 1B7TA 4IDZA 4JI8T 4B3MT 1Y01A 3FBZA 4P0BA 3OVUA 1XNQT 4TWHA 2ZM8A 5L3DB 2JQHA 2VQET 5C3JA 2N2NA 5AQKB 5FL1A 3AE4A 3RQWA 1KNRA 1ZKEA 1D0ZA 4KI0F 4YJ3E 2CHNA 3CX8B 4H63V 1ZP0A 4UXNB 4ZI3C 3SOLA 3H37A 4OK0A 1SA0E 2D9DA 3AE8A 2WMNA 1OXZA 2LE8A 2LT3A 3PU3A 4CXYA 3RYFE 3AA1B 1T72A 5LMNT 4EEDA 3J9X1 3PUSA 1ZV4X 3AAIA 3C4WA 2MAWA 2EHOD 1HR0T 4BJMA 3RIUA 4ANJA 5FKYA 2OA5A 1FEWA 1KF6A 4EAHA 3PJAA 2LLYA 5AQGB 2M67A 3Q9DA 4X5TA 5LGUB 1UUSA 5AFUL 4H9SE 4KX6A 2CRBA 2IC6A 4ADZA 2J62A 3RIUC 2M6BA 3AE1A 3L8RA 4WNKA 3OBVE 4U74A 3HI2A 3ZYMA 2B76A 2X0YA 2ACXA 4YTNA 2F4VT 4P0AA 4XAXB 2CWOA 2CWYA 4NXMT 2UXNB 2NR4A 4NXNT 2V5CA 2PTFA 4H9PC 4I50E 3C50A 4GOUA 2DCFA 3LG7A 4QHOA 3RIFA 2WMOA 4LF4T 5KXJA 2J47A 2UU9T 3MKDA 4G2AA 1IAPA 4UR9A 1ZHCA 3SWHA 2E9XD 4YLHA 3UUMA 2CXLA 4Z90A 3UUBA 3LK42 4PK5A 3UU6A 4GKKT 4EYYR 1VOMA 3FB2A 2H7OA 3TLVA 2JMKA 4GKJT 3RC8A 4HWHA 4HWDA 2XJ7A 2NW9A 2CBIA 3F31A 4ISSA 3KVAA 2EHOB 4AKLA 5FVKA 1CUNA 2XQ9A 1LVFA 2IMLA 4HWCA 4ZZCA 2AE9A 5ABFA 4ZHQE 1SUMB 3CWZB 4YSZA 5KDMC 4UIGA 5HEGA 2L3LA 1KNPA 4IIJE 3PUYF 3L39A 1XDOA 2LSIA 3K8PC 3NWIA 5L2LA 3UUXB 1XMOT 2Q9QA 5LNKA 1M62A 3BQIA 4U2ZA 3O1IA 2YK0A 2ES0A 3A5XA 4PK4A 2XQ7A 4GYRA 1VRBA 1XZYA 5J2UE 3RGLA 2X0LB 2E2AA 4HFIA 3OTOT 2Q9QC 3P4QA 3IEEA 1J5ET 5ABGA 1N36T 4AIUA 3ZKRA 4WBOA 3ZN1B 5A1LA 5CB4E 5HXSA 1WYCA 3KBTA 2VVSA 4U33A 4YHHT 4UVBB 5LHHB 4H9OC 2E9XB 2YEVC 2BBHA 4YJ2E 4ASKA 1S35A 3I1AA 4ZOLE 3S4UA 4DMWA 2VVNA 4HE8A 3U3IA 3RPUA 5HCMA 5M4YA 4A5XA 1O3XA 2NW8A 3AE2A 3ZMZB 4DNDA 3ANWB 3TLUA 4EXTA 2ZM6T 2J4GA 2WWVA 2D2SA 5HWYA 2VL8A 4EV6A 3RRCA 1KEYA 3NVOA 3J7Yq 3HA4A 4NUVA 2KSRA 4X1IE 3NKZA 2CBJA 2W61A 5IYZE 2WS3A 2UXBT 3ZMUB 4IE0A 1N33T 4H9RC 3VKHA 3U78A 4B6XA 4IDNA 5J1GA 4HTEA 4UF0A 2V5DA 4DBQA 2HH7A 1HTJF 3FXDB 4I55E 3M65A 4X20E 2X9XA 3KV6A 4LMLA 3ZC0A 4JI7T 2X0HA 5AQTB 1LVKA 3SRZA 4DR1T 2JQ9A 2XAQB 5FP3A 3GN5A 1E1HB 4B3ST 4OHFA 4A98A 4IL4A 3PURA 3L3PA 4ISTA 2Y48B 2V26A 2V7IA 2BBJA 4G63A 1JNRA 4AI6A 4ILUA 3LFMA 1XDPA 3T8OA 4B3RT 1D1AA 2XAHB 2WZHA 5FMNA 2CCQA 2IUBA 1MNDA 3Q5EA 4IE7A 2X68A 3P50A 5HEUA 5LG4A 2IIUA 1FMWA 3O4XE 1UK5A 3ZJ1A 1L0VA 5EK3A 4KHZF 4IGUA 2FJAA 5AQRB 2CLYC 3JC6C 4DBRA 4F6RC 4OX9T 4HWFA 3UFEA 1EZ3A 2XM1A 3T1YT 1NENA 4XBFB 5HXEA 4B3TT 3UFGA 2BKOA 3P4WA 5DQVA 2LJLA 3N9LA 2V7KA 4EIWA 2QRXA 5JRCB 4ZS2A 5FXXA 3SFDA 3KV4A 3UQ4A 3AXJB 3LBXB 2NW7A 3FZHB 3PUZF 2PFVA 2B1EA 2IAKA 4O4JE 3EVYA 2A72A 1YD8G 4QWNB 2CEAA 3Q5WA 3GMIA 4A97A 3PUWF 4JEUB 1ZEEA 3IA3A 5EK4A 1WLXA 2JPFA 5JH7E 2BKPA 3JAEA 3UU4A 3RYCE 1KFYA 2XUEA 4LF9T 2XSAA 2QGSA 4PK6A 2XPKA 4HFBA 2XASB 5HEJA 3EUHA 2D0TA 2UXCT 3UUNA 4MLKA 3RRWA 4DUZT 2HN1A 2VK9A 2LHRA 5AQFB 3CKDA 4L0RA 3VKGA 4OFZA 2H7VC 2LOSA 2YDQA 5ETWA 1HX8A 2V6XA 2FUPA 3BK9A 5AQNB 5L3EB 3ZEFB 2FJEA 3PUVF 4AKHA 5L3CB 2W62A 2DHRA 1FMVA 4NIQA 5L3GB 3C4ZA 1VCTA 2CXFA 2C5KT 2CMRA 5HXCA 4IT4A 3JAFA 3PUXF 3ZLIA 3K3OA 3RKOA 1WYBA 3DJBA 1AJ3A 3P7IA 4QH4A 4E7ZA 3PE0A 4Z91A 4FJOA 5EZYE 2XM2A 3C98B 1Z0PA 3K1SA 4AKRB 2VASA 2WDVA 4YSXA 3IBPA 1J1JA 3UU3A 4YT0A 5BR8T 3AEBA 3AAAB 1YQ3A 4GIWA 2NWBA 4HFVA 2FJDA 3G06A 5FXZA 4QKNA 4I4TE 4DV7T 3ZT7A 1UGOA 5JDHA 4IE5A 5LJNA 4YXDA 1QSDA 5HEHA 2PBIA 5JTGA 2LOPA 3NBXX 4BAYB 2BS4A 4GK5E 2K24A 2KINB 3ETVA 4JV5T 5AQMB 4DR7T 5LMUT 2W4XA 3AA0B 1MMDA 3AE5A 3IF8B 4DR2T 3T1HT 5DQWA 4EEBA 1D1CA 4QH5A 5F5WA 2ZM2A 2V6YB 3E08A 2LKHA 4YSYA 5H6QB 3FZLB 3UU8A 3P4RA 4ZI2D 5LOVE 2C5IT 2DWKA 4L5GA 4JEHB 4KHPT 5ABHA 3KFWX 3N9PA 3UULA 4QX7B 2KXPB 2L8KA 4PNIA 3ZSTA 1HX1B 1E7PA 2DLRA 4U3CA 3AEAA 4PJNA 2BG9B 4GYSA 4LFBT 3HL6A 1HNWT 4TNWA 2HN2A 3Q5DA 3CQCB 3RIAA 4U7YA 5LG3A 4AKIA 3A7MA 3PV0F 3OJAA 3V5SA 4IE6A 2E5LT 2C0SA 2YINA 1DU2A 4ILBA 5FXVA 3BQLA 1HS7A 3ZJ2A 2UXDT 4L9IA 2W2UA 2CE7A 3FZFB 4LF5T 2PG8A 2X51A 2I6HA 4TX5A 2LSYA 5AQQB 2EHOA 4HFEA 4KUMB 3VRAA 3GA8A 3O1JA 4C90A 3CK6A 3O9XA 3VRBA 4JYAT 1T7SA 3AE6A 3L09A 2I59A 3ZCJA 3NRYA 1WR6A 1UURA 3KDSE 2JQQA 4CI3B 1XMQT 4GK0E 3N2OA 2EHOC 5JDMA 2BG9C 2LSKA 1IBKT 3HKCE 4PAGA 4O4HE 2Y6XA 2L9QA 2W63A 2YDSA 4ZXLA 5LB7B 2BKNA 2OV9A 5C8YE 3PUGA 3ONXA 2ZLYA 1UX4A 1FIOA 2BVMA 2HHHT 4IREA 4DVDA 2LSGA 3UT5E 2WY2A 3OYZA 4UEMA 4HWIB 3ZT6A 1N32T 2WQYA 2VB6A 5EK2A 1US7B 4H63H 5IUXA 4X64T 1T8BA 4O4IE 4UVAB 2BZBA 2H88A 5AQSB 2NP9A 4ERRA 3LK2B 1Y64B 4Q25A 1NWMX 4EB6E 5GONE 1FJGT 3UQ7A 4HN9A 2OLTA 3AE9A 5AQIB 2LEHA 3P8CD 3EAMA 2E9XA 5CJ5A 4ZI7E 3UTKA 1OEDB 1HNXT 2A3DA 2V7MA 4IDQA 3CVRA 4WYVA 2MPKA 3KVBA 3FZMB 4DV3T 3ESLA 4PFPA 3ANWA 3AEDA 3CIRA 4TUYE 1OWAA 5J2TE 1D1BA 3H3AA 2E9XC 3TLSA 2V7JA 2JJ9A 2QVAA 4LMJA 1D0XA 3AEFA 4DV0T 5AQPB 4BA9A 1NAFA 4OYJA 5L3FB 5LCYA 4FI5A 5FXWA 1X9BA 3SFEA 2J1DG 3R84B 1GQEA 3EDUA 4JI2T 1W09A 5IWAT 1OEDC 3RKGA 2YN6A 3EI0A 2UXXB 4WZXA 4DUYT 5LP6E 4TV8E 3MJXA 1HG2A 5AQUB 1HF8A 2CPTA 5JQGE 5JR9B 2H3RA 4HFCA 3F2EA 3TKLB 2XQYA 4EOZB 3VR8A 1E2AA 2XSBA 4PJMA 5LGNB 4DR6T 4CN4A 1MMGA 2Y8DA 3UU5A 1N34T 2XAJB 3CMLA 5CA1E 3ZCIA 3K3NA 2XAGB 2HPLA 1SE7A 2BDEA 5HWXA 1MIYA 4ILAA 2R6GF 4WBNE 3N9MA 3FBLA 2A9UA 4ZEYA 1BR2A 3FZKB 4CZZB 4CN6A 3N2GE 4YFSA 1I94T 4MBQA 2VKOA 3PTRB 2JRKA 3I0OA 1KNZA 4DR5T 4F8HA 4DV2T 4KMCA 2QYWA 3F57A 1WFDA 3EHZA 3QUJA 1WRDA 3RYIE 3KV9A 5LBQB 3RX6A 3P4PA 4QH1A 1H7CA 3K3QC 4X65T 4YHJA 3B5MA 3ONJA 3RLFF 3RQUA 3E22E 1LRZA 5AQHB 1YKEB 3AA7B 5LHGB 4LF6T 2RA1A 2WWUA 3O1HA 3QB5K 5CA0E 2WSSV 3DTOA 5JRCA 5L4HA 2A2FX 5L47A 5JREA 3ZSSA 2XY8B 3PUAA 4NPPA 2PJQA 2LRKA 3AXJA 3AE3A 4X66T 2KMFA 4UV9B 3LBXA 1IBMT 1XWMA 3H3MA 1XNRT 4O8SA 4IDPA 3KBUA 4ZZBA 4E7SA 2UUAT 2WB5A 1R8IA 1X79A 5AQVB 2LRLA 1CHUA 2BVLA 4UELA 4C91A 3HKEE 4X1KE 4LFCT 4J2CA 4DV1T 4Z8XA 2RP4A 5JDLA 1SHZC 5HAXA 4LF8T 4MHCA 5FL0A 3DP7A 2X9HA 1MNEA 4TWFA 1M7KA 2VWAA 2E5VA 5TAOA 2IHR1 4AQGA 2XQ6A 3QOFA 2V1DB 1ZOYA 4CQIA 4ILCA 4K0KT 1HCIA 3AA6B 1LKXA 3FXEB 3N9QA 2JIWA 5JDQA 1G8XA 2WDRA 4P09A 3TLWA 3WAKA 3P4SA 2BS3A 3QK6A 2CXDA 4EZHA 1IJ5A 3AECA 3ZPOA 5FYMA 3RC3A 4QX8B 2K5BB 5AQLB 2P9BA 4COFA 5JVDE 3JCFA 3RI5A 4LF7T 4U31A 1HG5A 4HGAA 1QUUA 2VKJA 2Q9QD 3RHWA 1IBLT 4AQYT 5FY0A 2RPAA 5IHYA 5JDFA 2DNXA 2W0GA 4WW0A 5FY1A 4UV8B 1W9RA 3B57A 3ETUA 5BMVE 5LJMA 1D0YA 2WCAA 4JI3T 4TZ4C 1S94A 4CXWA 2XQAA 4HFHA 5CFBA 4AXPA 5HCJA 4X1YE 3PJAJ 3C4XA 3C51A 2MTQA 3QNUA 2HPJA 1YW0A 4P1NA 4JLEA 5FNVE 3ABVA 4QXCB 3ONLC 4DR4T 3PDYA 5H6RB 3PUQA 3Q2MA 2M6IA 1WR0A 2VKDA 1YQ4A 2V8SV 4U2YA 3IHRA 4I43B 4QXBB 4IDOA 2UUBT 5C2TA 4TN7B 2BG9E 2VQFT 2X67A 3A8YC 3W15B 2WDQA 3ZC1A 3LDQB 3QC9A 2X66A 3CQXC 3RF1A 2V6YA 2IC9A 1V9DA 2H89A 2K48A 5CGMA 4DV4T 2WU5A 2N1GA 5ADXL 2IW5B 5JDGA 3CX6B 5ABFB 3ZYLA 1BR1A 4CI2B 2UUCT 2C5JA 2K3WA 2K9AA 3ZN0B 4EGWA 1BR0A 5E0OA 3N9OA 3MACA 4V1Av 4IE4A 3NRXA 3OKQA 4JI0T 2WAUA 3LJCA 3N2KE 3OYXA 2BG9A 2BS2A 5L3BB 2Q9QB 1Z8UA 2LKGA 3D0TA 1I6ZA 3B13A 5F3JA 4O4LE 2VKHA 4IL9A 4I0UA 1WCRA 4JI5T 5HYAA 4XZCA 3ZMTB 2X9YA 1MIWA 3NZPA 4O2BE 3AAEB 4DIDB 1KK7A 2CHOA 4U7IA 1YXRA 1UX5A 4X62T 3SS1A 1MMAA 4PW8A 2VURA 4N78D 2WM9A 4LFAT 4YTPA 3FHNA 2W66A 4PFOA 1W0AA 1U4QA 3KINB 2JMHA 3AEGA 3BQKA 2LM9A 2KNDA 1BR4A 3JC6D 5F8PA 4JI4T 2ZM0A 2KWIB 3LK3B 4AISA 5HEOA 4DV6T 2Z6EA 1OEDE 5KX5E 5LA6E 3JADA 2YOEA 1NEKA 3V5UA 3WI3A 1T98A 2E8IA 2XQ3A 4DMVA 2KT9A 3R6NA 3LSVA 2XQ5A 2YU2A 4TNVA 2MBGA 4EYUA 4YY3T 4QXHB 2NTYA 4KP3C 3VU7H 4AQFA 3ZT5A 4TWDA 2W00A 3CPZA 4HKAA 3ZYKA 3KV5A 4JBWF 5AQJB 3QB5A 4UF0B 2ZMAA 4BJNA 5LBMA 4PJLA 4KBMB 2CM0A 3C64A 2YDRA 5AQOB 4ZI2C 4EZ4A 2VL0A 4YTMA 4M1PA 1UCUA 3EDVA 3CQGB 2D0UA 3RH3A 1OEDA 4AQFC 5LYJE 4MFRA 2KLQA 4DO0A 4CXXA 2NOXA 2DI4A 3GN5B 2XAFB 3VR9A 4CN1A 2YU1A 1G73A 3HKDE 2D5UA 5LHIB 1IJ6A 3MXZA 1IZNB 3VHLA 2MOZA 5KMGP 3RYHE 5HXHA 5JDNA 4MALA 1QLBA 2KZ7B 2XZEA 3ZMSB 1JNZA 4ZI3D 2CLYB 2SPCA 3PU8A 2XQ4A 2KWHA 2XQ8A 2LM2A 2JQKA 2X9WA 3X1DA 3I0QA 4DR3T 3NZQA 2N9DA 5LXTE 4H9NC 3OPCA 2XTLA 4CI1B 2IDOB 5JR9A 3Q5XA 4O2AE 2NTXA 3AVSA 4DV5T 2ODUA 2ACZA 2LHNA 5ABEA 5FVLA 2YKSA 4OYKA 3HR0A 3AB3B 1HFAA 2QA7A 4ZS3A 2FJBA 4HEAA 4AKGA 2WBLA 5FY7A 3AE7A 3CX7B 2FBWA 4NUUA 5JR9C 1U5PA 2W67A 2MYSA 1J5WA 3MZKB 2V7LA 4HFDA 5HXRA 5LGTB 1HNZT 2GK9A 3I9WA 3MA9A 2I0MA 4U72A 2DWGA 4JI1T 3TLTA 4TV9E 2LSJA 3WAJA 3ZMVB 1W0BA 5J0ZA 5DJQC 1VCSA 4JUYA 1MIVA 3M3ZB 3EABA 3GWHA 3N5LA 3HKBE 3E0ZA 2WZIA 1YKHB 2XHEB 5DABA 2G0UA 2CA5A 1MMNA 2ODVA 2WP9A 3MK7C 2DL1A 3AVRA 4IHJE
chains in the Genus database with same CATH topology
3M3ZB 5AQIB 1UGOA 5AQNB 5AQTB 3FZFB 5AQHB 1M7KA 5AQLB 5AQRB 2D9DA 5AQVB 5AQSB 5AQQB 3FZHB 5AQOB 5AQUB 5AQFB 3A8YC 4HWCA 5AQKB 4HWFA 3LDQB 4HWIB 5AQPB 4HWHA 1UK5A 1HX1B 4HWDA 1T7SA 5AQJB 3FZMB 1I6ZA 1M62A 3FZLB 5AQGB 5AQMB 3FZKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M3Z B;  5AQI B;  1UGO A;  5AQN B;  5AQT B;  3FZF B;  5AQH B;  1M7K A;  5AQL B;  5AQR B;  2D9D A;  5AQV B;  5AQS B;  5AQQ B;  3FZH B;  5AQO B;  5AQU B;  5AQF B;  3A8Y C;  4HWC A;  5AQK B;  4HWF A;  3LDQ B;  4HWI B;  5AQP B;  4HWH A;  1UK5 A;  1HX1 B;  4HWD A;  1T7S A;  5AQJ B;  3FZM B;  1I6Z A;  1M62 A;  3FZL B;  5AQG B;  5AQM B;  3FZK B; 
#chains in the Genus database with same CATH topology
 2WU2 A;  2AXD S;  4LMK A;  4UVC B;  4H9Q C;  5L4E A;  4K0U A;  3AEE A;  4A56 A;  4PJJ A;  3N9N A;  3I9Y A;  4JI6 T;  1B7T A;  4IDZ A;  4JI8 T;  4B3M T;  1Y01 A;  3FBZ A;  4P0B A;  3OVU A;  1XNQ T;  4TWH A;  2ZM8 A;  5L3D B;  2JQH A;  2VQE T;  5C3J A;  2N2N A;  5AQK B;  5FL1 A;  3AE4 A;  3RQW A;  1KNR A;  1ZKE A;  1D0Z A;  4KI0 F;  4YJ3 E;  2CHN A;  3CX8 B;  4H63 V;  1ZP0 A;  4UXN B;  4ZI3 C;  3SOL A;  3H37 A;  4OK0 A;  1SA0 E;  2D9D A;  3AE8 A;  2WMN A;  1OXZ A;  2LE8 A;  2LT3 A;  3PU3 A;  4CXY A;  3RYF E;  3AA1 B;  1T72 A;  5LMN T;  4EED A;  3J9X 1;  3PUS A;  1ZV4 X;  3AAI A;  3C4W A;  2MAW A;  2EHO D;  1HR0 T;  4BJM A;  3RIU A;  4ANJ A;  5FKY A;  2OA5 A;  1FEW A;  1KF6 A;  4EAH A;  3PJA A;  2LLY A;  5AQG B;  2M67 A;  3Q9D A;  4X5T A;  5LGU B;  1UUS A;  5AFU L;  4H9S E;  4KX6 A;  2CRB A;  2IC6 A;  4ADZ A;  2J62 A;  3RIU C;  2M6B A;  3AE1 A;  3L8R A;  4WNK A;  3OBV E;  4U74 A;  3HI2 A;  3ZYM A;  2B76 A;  2X0Y A;  2ACX A;  4YTN A;  2F4V T;  4P0A A;  4XAX B;  2CWO A;  2CWY A;  4NXM T;  2UXN B;  2NR4 A;  4NXN T;  2V5C A;  2PTF A;  4H9P C;  4I50 E;  3C50 A;  4GOU A;  2DCF A;  3LG7 A;  4QHO A;  3RIF A;  2WMO A;  4LF4 T;  5KXJ A;  2J47 A;  2UU9 T;  3MKD A;  4G2A A;  1IAP A;  4UR9 A;  1ZHC A;  3SWH A;  2E9X D;  4YLH A;  3UUM A;  2CXL A;  4Z90 A;  3UUB A;  3LK4 2;  4PK5 A;  3UU6 A;  4GKK T;  4EYY R;  1VOM A;  3FB2 A;  2H7O A;  3TLV A;  2JMK A;  4GKJ T;  3RC8 A;  4HWH A;  4HWD A;  2XJ7 A;  2NW9 A;  2CBI A;  3F31 A;  4ISS A;  3KVA A;  2EHO B;  4AKL A;  5FVK A;  1CUN A;  2XQ9 A;  1LVF A;  2IML A;  4HWC A;  4ZZC A;  2AE9 A;  5ABF A;  4ZHQ E;  1SUM B;  3CWZ B;  4YSZ A;  5KDM C;  4UIG A;  5HEG A;  2L3L A;  1KNP A;  4IIJ E;  3PUY F;  3L39 A;  1XDO A;  2LSI A;  3K8P C;  3NWI A;  5L2L A;  3UUX B;  1XMO T;  2Q9Q A;  5LNK A;  1M62 A;  3BQI A;  4U2Z A;  3O1I A;  2YK0 A;  2ES0 A;  3A5X A;  4PK4 A;  2XQ7 A;  4GYR A;  1VRB A;  1XZY A;  5J2U E;  3RGL A;  2X0L B;  2E2A A;  4HFI A;  3OTO T;  2Q9Q C;  3P4Q A;  3IEE A;  1J5E T;  5ABG A;  1N36 T;  4AIU A;  3ZKR A;  4WBO A;  3ZN1 B;  5A1L A;  5CB4 E;  5HXS A;  1WYC A;  3KBT A;  2VVS A;  4U33 A;  4YHH T;  4UVB B;  5LHH B;  4H9O C;  2E9X B;  2YEV C;  2BBH A;  4YJ2 E;  4ASK A;  1S35 A;  3I1A A;  4ZOL E;  3S4U A;  4DMW A;  2VVN A;  4HE8 A;  3U3I A;  3RPU A;  5HCM A;  5M4Y A;  4A5X A;  1O3X A;  2NW8 A;  3AE2 A;  3ZMZ B;  4DND A;  3ANW B;  3TLU A;  4EXT A;  2ZM6 T;  2J4G A;  2WWV A;  2D2S A;  5HWY A;  2VL8 A;  4EV6 A;  3RRC A;  1KEY A;  3NVO A;  3J7Y q;  3HA4 A;  4NUV A;  2KSR A;  4X1I E;  3NKZ A;  2CBJ A;  2W61 A;  5IYZ E;  2WS3 A;  2UXB T;  3ZMU B;  4IE0 A;  1N33 T;  4H9R C;  3VKH A;  3U78 A;  4B6X A;  4IDN A;  5J1G A;  4HTE A;  4UF0 A;  2V5D A;  4DBQ A;  2HH7 A;  1HTJ F;  3FXD B;  4I55 E;  3M65 A;  4X20 E;  2X9X A;  3KV6 A;  4LML A;  3ZC0 A;  4JI7 T;  2X0H A;  5AQT B;  1LVK A;  3SRZ A;  4DR1 T;  2JQ9 A;  2XAQ B;  5FP3 A;  3GN5 A;  1E1H B;  4B3S T;  4OHF A;  4A98 A;  4IL4 A;  3PUR A;  3L3P A;  4IST A;  2Y48 B;  2V26 A;  2V7I A;  2BBJ A;  4G63 A;  1JNR A;  4AI6 A;  4ILU A;  3LFM A;  1XDP A;  3T8O A;  4B3R T;  1D1A A;  2XAH B;  2WZH A;  5FMN A;  2CCQ A;  2IUB A;  1MND A;  3Q5E A;  4IE7 A;  2X68 A;  3P50 A;  5HEU A;  5LG4 A;  2IIU A;  1FMW A;  3O4X E;  1UK5 A;  3ZJ1 A;  1L0V A;  5EK3 A;  4KHZ F;  4IGU A;  2FJA A;  5AQR B;  2CLY C;  3JC6 C;  4DBR A;  4F6R C;  4OX9 T;  4HWF A;  3UFE A;  1EZ3 A;  2XM1 A;  3T1Y T;  1NEN A;  4XBF B;  5HXE A;  4B3T T;  3UFG A;  2BKO A;  3P4W A;  5DQV A;  2LJL A;  3N9L A;  2V7K A;  4EIW A;  2QRX A;  5JRC B;  4ZS2 A;  5FXX A;  3SFD A;  3KV4 A;  3UQ4 A;  3AXJ B;  3LBX B;  2NW7 A;  3FZH B;  3PUZ F;  2PFV A;  2B1E A;  2IAK A;  4O4J E;  3EVY A;  2A72 A;  1YD8 G;  4QWN B;  2CEA A;  3Q5W A;  3GMI A;  4A97 A;  3PUW F;  4JEU B;  1ZEE A;  3IA3 A;  5EK4 A;  1WLX A;  2JPF A;  5JH7 E;  2BKP A;  3JAE A;  3UU4 A;  3RYC E;  1KFY A;  2XUE A;  4LF9 T;  2XSA A;  2QGS A;  4PK6 A;  2XPK A;  4HFB A;  2XAS B;  5HEJ A;  3EUH A;  2D0T A;  2UXC T;  3UUN A;  4MLK A;  3RRW A;  4DUZ T;  2HN1 A;  2VK9 A;  2LHR A;  5AQF B;  3CKD A;  4L0R A;  3VKG A;  4OFZ A;  2H7V C;  2LOS A;  2YDQ A;  5ETW A;  1HX8 A;  2V6X A;  2FUP A;  3BK9 A;  5AQN B;  5L3E B;  3ZEF B;  2FJE A;  3PUV F;  4AKH A;  5L3C B;  2W62 A;  2DHR A;  1FMV A;  4NIQ A;  5L3G B;  3C4Z A;  1VCT A;  2CXF A;  2C5K T;  2CMR A;  5HXC A;  4IT4 A;  3JAF A;  3PUX F;  3ZLI A;  3K3O A;  3RKO A;  1WYB A;  3DJB A;  1AJ3 A;  3P7I A;  4QH4 A;  4E7Z A;  3PE0 A;  4Z91 A;  4FJO A;  5EZY E;  2XM2 A;  3C98 B;  1Z0P A;  3K1S A;  4AKR B;  2VAS A;  2WDV A;  4YSX A;  3IBP A;  1J1J A;  3UU3 A;  4YT0 A;  5BR8 T;  3AEB A;  3AAA B;  1YQ3 A;  4GIW A;  2NWB A;  4HFV A;  2FJD A;  3G06 A;  5FXZ A;  4QKN A;  4I4T E;  4DV7 T;  3ZT7 A;  1UGO A;  5JDH A;  4IE5 A;  5LJN A;  4YXD A;  1QSD A;  5HEH A;  2PBI A;  5JTG A;  2LOP A;  3NBX X;  4BAY B;  2BS4 A;  4GK5 E;  2K24 A;  2KIN B;  3ETV A;  4JV5 T;  5AQM B;  4DR7 T;  5LMU T;  2W4X A;  3AA0 B;  1MMD A;  3AE5 A;  3IF8 B;  4DR2 T;  3T1H T;  5DQW A;  4EEB A;  1D1C A;  4QH5 A;  5F5W A;  2ZM2 A;  2V6Y B;  3E08 A;  2LKH A;  4YSY A;  5H6Q B;  3FZL B;  3UU8 A;  3P4R A;  4ZI2 D;  5LOV E;  2C5I T;  2DWK A;  4L5G A;  4JEH B;  4KHP T;  5ABH A;  3KFW X;  3N9P A;  3UUL A;  4QX7 B;  2KXP B;  2L8K A;  4PNI A;  3ZST A;  1HX1 B;  1E7P A;  2DLR A;  4U3C A;  3AEA A;  4PJN A;  2BG9 B;  4GYS A;  4LFB T;  3HL6 A;  1HNW T;  4TNW A;  2HN2 A;  3Q5D A;  3CQC B;  3RIA A;  4U7Y A;  5LG3 A;  4AKI A;  3A7M A;  3PV0 F;  3OJA A;  3V5S A;  4IE6 A;  2E5L T;  2C0S A;  2YIN A;  1DU2 A;  4ILB A;  5FXV A;  3BQL A;  1HS7 A;  3ZJ2 A;  2UXD T;  4L9I A;  2W2U A;  2CE7 A;  3FZF B;  4LF5 T;  2PG8 A;  2X51 A;  2I6H A;  4TX5 A;  2LSY A;  5AQQ B;  2EHO A;  4HFE A;  4KUM B;  3VRA A;  3GA8 A;  3O1J A;  4C90 A;  3CK6 A;  3O9X A;  3VRB A;  4JYA T;  1T7S A;  3AE6 A;  3L09 A;  2I59 A;  3ZCJ A;  3NRY A;  1WR6 A;  1UUR A;  3KDS E;  2JQQ A;  4CI3 B;  1XMQ T;  4GK0 E;  3N2O A;  2EHO C;  5JDM A;  2BG9 C;  2LSK A;  1IBK T;  3HKC E;  4PAG A;  4O4H E;  2Y6X A;  2L9Q A;  2W63 A;  2YDS A;  4ZXL A;  5LB7 B;  2BKN A;  2OV9 A;  5C8Y E;  3PUG A;  3ONX A;  2ZLY A;  1UX4 A;  1FIO A;  2BVM A;  2HHH T;  4IRE A;  4DVD A;  2LSG A;  3UT5 E;  2WY2 A;  3OYZ A;  4UEM A;  4HWI B;  3ZT6 A;  1N32 T;  2WQY A;  2VB6 A;  5EK2 A;  1US7 B;  4H63 H;  5IUX A;  4X64 T;  1T8B A;  4O4I E;  4UVA B;  2BZB A;  2H88 A;  5AQS B;  2NP9 A;  4ERR A;  3LK2 B;  1Y64 B;  4Q25 A;  1NWM X;  4EB6 E;  5GON E;  1FJG T;  3UQ7 A;  4HN9 A;  2OLT A;  3AE9 A;  5AQI B;  2LEH A;  3P8C D;  3EAM A;  2E9X A;  5CJ5 A;  4ZI7 E;  3UTK A;  1OED B;  1HNX T;  2A3D A;  2V7M A;  4IDQ A;  3CVR A;  4WYV A;  2MPK A;  3KVB A;  3FZM B;  4DV3 T;  3ESL A;  4PFP A;  3ANW A;  3AED A;  3CIR A;  4TUY E;  1OWA A;  5J2T E;  1D1B A;  3H3A A;  2E9X C;  3TLS A;  2V7J A;  2JJ9 A;  2QVA A;  4LMJ A;  1D0X A;  3AEF A;  4DV0 T;  5AQP B;  4BA9 A;  1NAF A;  4OYJ A;  5L3F B;  5LCY A;  4FI5 A;  5FXW A;  1X9B A;  3SFE A;  2J1D G;  3R84 B;  1GQE A;  3EDU A;  4JI2 T;  1W09 A;  5IWA T;  1OED C;  3RKG A;  2YN6 A;  3EI0 A;  2UXX B;  4WZX A;  4DUY T;  5LP6 E;  4TV8 E;  3MJX A;  1HG2 A;  5AQU B;  1HF8 A;  2CPT A;  5JQG E;  5JR9 B;  2H3R A;  4HFC A;  3F2E A;  3TKL B;  2XQY A;  4EOZ B;  3VR8 A;  1E2A A;  2XSB A;  4PJM A;  5LGN B;  4DR6 T;  4CN4 A;  1MMG A;  2Y8D A;  3UU5 A;  1N34 T;  2XAJ B;  3CML A;  5CA1 E;  3ZCI A;  3K3N A;  2XAG B;  2HPL A;  1SE7 A;  2BDE A;  5HWX A;  1MIY A;  4ILA A;  2R6G F;  4WBN E;  3N9M A;  3FBL A;  2A9U A;  4ZEY A;  1BR2 A;  3FZK B;  4CZZ B;  4CN6 A;  3N2G E;  4YFS A;  1I94 T;  4MBQ A;  2VKO A;  3PTR B;  2JRK A;  3I0O A;  1KNZ A;  4DR5 T;  4F8H A;  4DV2 T;  4KMC A;  2QYW A;  3F57 A;  1WFD A;  3EHZ A;  3QUJ A;  1WRD A;  3RYI E;  3KV9 A;  5LBQ B;  3RX6 A;  3P4P A;  4QH1 A;  1H7C A;  3K3Q C;  4X65 T;  4YHJ A;  3B5M A;  3ONJ A;  3RLF F;  3RQU A;  3E22 E;  1LRZ A;  5AQH B;  1YKE B;  3AA7 B;  5LHG B;  4LF6 T;  2RA1 A;  2WWU A;  3O1H A;  3QB5 K;  5CA0 E;  2WSS V;  3DTO A;  5JRC A;  5L4H A;  2A2F X;  5L47 A;  5JRE A;  3ZSS A;  2XY8 B;  3PUA A;  4NPP A;  2PJQ A;  2LRK A;  3AXJ A;  3AE3 A;  4X66 T;  2KMF A;  4UV9 B;  3LBX A;  1IBM T;  1XWM A;  3H3M A;  1XNR T;  4O8S A;  4IDP A;  3KBU A;  4ZZB A;  4E7S A;  2UUA T;  2WB5 A;  1R8I A;  1X79 A;  5AQV B;  2LRL A;  1CHU A;  2BVL A;  4UEL A;  4C91 A;  3HKE E;  4X1K E;  4LFC T;  4J2C A;  4DV1 T;  4Z8X A;  2RP4 A;  5JDL A;  1SHZ C;  5HAX A;  4LF8 T;  4MHC A;  5FL0 A;  3DP7 A;  2X9H A;  1MNE A;  4TWF A;  1M7K A;  2VWA A;  2E5V A;  5TAO A;  2IHR 1;  4AQG A;  2XQ6 A;  3QOF A;  2V1D B;  1ZOY A;  4CQI A;  4ILC A;  4K0K T;  1HCI A;  3AA6 B;  1LKX A;  3FXE B;  3N9Q A;  2JIW A;  5JDQ A;  1G8X A;  2WDR A;  4P09 A;  3TLW A;  3WAK A;  3P4S A;  2BS3 A;  3QK6 A;  2CXD A;  4EZH A;  1IJ5 A;  3AEC A;  3ZPO A;  5FYM A;  3RC3 A;  4QX8 B;  2K5B B;  5AQL B;  2P9B A;  4COF A;  5JVD E;  3JCF A;  3RI5 A;  4LF7 T;  4U31 A;  1HG5 A;  4HGA A;  1QUU A;  2VKJ A;  2Q9Q D;  3RHW A;  1IBL T;  4AQY T;  5FY0 A;  2RPA A;  5IHY A;  5JDF A;  2DNX A;  2W0G A;  4WW0 A;  5FY1 A;  4UV8 B;  1W9R A;  3B57 A;  3ETU A;  5BMV E;  5LJM A;  1D0Y A;  2WCA A;  4JI3 T;  4TZ4 C;  1S94 A;  4CXW A;  2XQA A;  4HFH A;  5CFB A;  4AXP A;  5HCJ A;  4X1Y E;  3PJA J;  3C4X A;  3C51 A;  2MTQ A;  3QNU A;  2HPJ A;  1YW0 A;  4P1N A;  4JLE A;  5FNV E;  3ABV A;  4QXC B;  3ONL C;  4DR4 T;  3PDY A;  5H6R B;  3PUQ A;  3Q2M A;  2M6I A;  1WR0 A;  2VKD A;  1YQ4 A;  2V8S V;  4U2Y A;  3IHR A;  4I43 B;  4QXB B;  4IDO A;  2UUB T;  5C2T A;  4TN7 B;  2BG9 E;  2VQF T;  2X67 A;  3A8Y C;  3W15 B;  2WDQ A;  3ZC1 A;  3LDQ B;  3QC9 A;  2X66 A;  3CQX C;  3RF1 A;  2V6Y A;  2IC9 A;  1V9D A;  2H89 A;  2K48 A;  5CGM A;  4DV4 T;  2WU5 A;  2N1G A;  5ADX L;  2IW5 B;  5JDG A;  3CX6 B;  5ABF B;  3ZYL A;  1BR1 A;  4CI2 B;  2UUC T;  2C5J A;  2K3W A;  2K9A A;  3ZN0 B;  4EGW A;  1BR0 A;  5E0O A;  3N9O A;  3MAC A;  4V1A v;  4IE4 A;  3NRX A;  3OKQ A;  4JI0 T;  2WAU A;  3LJC A;  3N2K E;  3OYX A;  2BG9 A;  2BS2 A;  5L3B B;  2Q9Q B;  1Z8U A;  2LKG A;  3D0T A;  1I6Z A;  3B13 A;  5F3J A;  4O4L E;  2VKH A;  4IL9 A;  4I0U A;  1WCR A;  4JI5 T;  5HYA A;  4XZC A;  3ZMT B;  2X9Y A;  1MIW A;  3NZP A;  4O2B E;  3AAE B;  4DID B;  1KK7 A;  2CHO A;  4U7I A;  1YXR A;  1UX5 A;  4X62 T;  3SS1 A;  1MMA A;  4PW8 A;  2VUR A;  4N78 D;  2WM9 A;  4LFA T;  4YTP A;  3FHN A;  2W66 A;  4PFO A;  1W0A A;  1U4Q A;  3KIN B;  2JMH A;  3AEG A;  3BQK A;  2LM9 A;  2KND A;  1BR4 A;  3JC6 D;  5F8P A;  4JI4 T;  2ZM0 A;  2KWI B;  3LK3 B;  4AIS A;  5HEO A;  4DV6 T;  2Z6E A;  1OED E;  5KX5 E;  5LA6 E;  3JAD A;  2YOE A;  1NEK A;  3V5U A;  3WI3 A;  1T98 A;  2E8I A;  2XQ3 A;  4DMV A;  2KT9 A;  3R6N A;  3LSV A;  2XQ5 A;  2YU2 A;  4TNV A;  2MBG A;  4EYU A;  4YY3 T;  4QXH B;  2NTY A;  4KP3 C;  3VU7 H;  4AQF A;  3ZT5 A;  4TWD A;  2W00 A;  3CPZ A;  4HKA A;  3ZYK A;  3KV5 A;  4JBW F;  5AQJ B;  3QB5 A;  4UF0 B;  2ZMA A;  4BJN A;  5LBM A;  4PJL A;  4KBM B;  2CM0 A;  3C64 A;  2YDR A;  5AQO B;  4ZI2 C;  4EZ4 A;  2VL0 A;  4YTM A;  4M1P A;  1UCU A;  3EDV A;  3CQG B;  2D0U A;  3RH3 A;  1OED A;  4AQF C;  5LYJ E;  4MFR A;  2KLQ A;  4DO0 A;  4CXX A;  2NOX A;  2DI4 A;  3GN5 B;  2XAF B;  3VR9 A;  4CN1 A;  2YU1 A;  1G73 A;  3HKD E;  2D5U A;  5LHI B;  1IJ6 A;  3MXZ A;  1IZN B;  3VHL A;  2MOZ A;  5KMG P;  3RYH E;  5HXH A;  5JDN A;  4MAL A;  1QLB A;  2KZ7 B;  2XZE A;  3ZMS B;  1JNZ A;  4ZI3 D;  2CLY B;  2SPC A;  3PU8 A;  2XQ4 A;  2KWH A;  2XQ8 A;  2LM2 A;  2JQK A;  2X9W A;  3X1D A;  3I0Q A;  4DR3 T;  3NZQ A;  2N9D A;  5LXT E;  4H9N C;  3OPC A;  2XTL A;  4CI1 B;  2IDO B;  5JR9 A;  3Q5X A;  4O2A E;  2NTX A;  3AVS A;  4DV5 T;  2ODU A;  2ACZ A;  2LHN A;  5ABE A;  5FVL A;  2YKS A;  4OYK A;  3HR0 A;  3AB3 B;  1HFA A;  2QA7 A;  4ZS3 A;  2FJB A;  4HEA A;  4AKG A;  2WBL A;  5FY7 A;  3AE7 A;  3CX7 B;  2FBW A;  4NUU A;  5JR9 C;  1U5P A;  2W67 A;  2MYS A;  1J5W A;  3MZK B;  2V7L A;  4HFD A;  5HXR A;  5LGT B;  1HNZ T;  2GK9 A;  3I9W A;  3MA9 A;  2I0M A;  4U72 A;  2DWG A;  4JI1 T;  3TLT A;  4TV9 E;  2LSJ A;  3WAJ A;  3ZMV B;  1W0B A;  5J0Z A;  5DJQ C;  1VCS A;  4JUY A;  1MIV A;  3M3Z B;  3EAB A;  3GWH A;  3N5L A;  3HKB E;  3E0Z A;  2WZI A;  1YKH B;  2XHE B;  5DAB A;  2G0U A;  2CA5 A;  1MMN A;  2ODV A;  2WP9 A;  3MK7 C;  2DL1 A;  3AVR A;  4IHJ E; 
#chains in the Genus database with same CATH homology
 3M3Z B;  5AQI B;  1UGO A;  5AQN B;  5AQT B;  3FZF B;  5AQH B;  1M7K A;  5AQL B;  5AQR B;  2D9D A;  5AQV B;  5AQS B;  5AQQ B;  3FZH B;  5AQO B;  5AQU B;  5AQF B;  3A8Y C;  4HWC A;  5AQK B;  4HWF A;  3LDQ B;  4HWI B;  5AQP B;  4HWH A;  1UK5 A;  1HX1 B;  4HWD A;  1T7S A;  5AQJ B;  3FZM B;  1I6Z A;  1M62 A;  3FZL B;  5AQG B;  5AQM B;  3FZK B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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