5AQIB

Fragment-based screening of hsp70 sheds light on the functional role of atp-binding site residues
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
112
structure length
112
Chain Sequence
SNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
pubmed doi rcsb
molecule tags Chaperone
source organism Homo sapiens
molecule keywords HEAT SHOCK COGNATE 71 KDA PROTEIN
total genus 45
structure length 112
sequence length 112
chains with identical sequence D
ec nomenclature
pdb deposition date 2015-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02179 BAG BAG domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.58.120 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase; Chain G, domain 1 BAG domain 5aqiB00
3FZKB 5AQUB 5AQFB 3M3ZB 5AQNB 4HWDA 5AQHB 3FZHB 1HX1B 5AQRB 1M7KA 5AQLB 1UK5A 5AQMB 4HWIB 5AQTB 5AQOB 1I6ZA 5AQSB 2D9DA 3LDQB 5AQVB 3FZMB 5AQKB 5AQQB 3FZLB 5AQIB 1T7SA 5AQPB 1UGOA 5AQGB 3FZFB 4HWFA 1M62A 4HWCA 3A8YC 4HWHA 5AQJB
chains in the Genus database with same CATH superfamily
5AFUL 2FBWA 2WDQA 2H7OA 2WU5A 2BS4A 1XZYA 3PUQA 3TLVA 1WR0A 2LKGA 2AXDS 3CX8B 2D9DA 2E9XD 2WWVA 1MMGA 3OPCA 2VB6A 4O8SA 5AQGB 3PJAJ 4JLEA 5HEUA 1IAPA 3UU3A 2JQKA 4PFPA 5L4EA 4CXXA 5J2TE 4DR4T 4EZHA 3RI5A 3F57A 5H6RB 4YJ3E 5FXWA 2W61A 4JI3T 3CQGB 2ACZA 2WM9A 4H9PC 4DV2T 2LT3A 4I50E 2YDSA 1KNRA 2KT9A 2NWBA 3CIRA 2KSRA 4OFZA 2NTYA 2DHRA 4GK0E 3ZC0A 2XM2A 3JC6C 3UULA 2H3RA 4E7ZA 4QX7B 2XQ7A 1E2AA 5H6QB 3P4RA 1HF8A 2Q9QB 3ZSSA 3C64A 4YXDA 2ZM2A 1KF6A 4X5TA 4JEHB 3ZYMA 3KV6A 5LXTE 5AQUB 2RPAA 5F3JA 4UV9B 2XHEB 3N9QA 4I0UA 3TLWA 4DR2T 2LJLA 3ZMSB 2IHR1 2V1DB 3ZYKA 5AQJB 1T98A 1G8XA 2E8IA 1N36T 2HHHT 4U2ZA 1N33T 3AEFA 2WCAA 3ZMUB 4NXMT 4AQYT 2XY8B 2A2FX 2QVAA 2X0LB 5HWYA 3UU4A 2LRLA 5FKYA 4EZ4A 3QK6A 4ZI7E 4IREA 3PUYF 2KINB 5ADXL 3T8OA 2LLYA 2YINA 4ZZCA 2K3WA 5JR9C 4ZEYA 4YSYA 2WDRA 3RKOA 3P4PA 4A56A 2LM9A 3ZJ1A 5FP3A 2VKHA 3UT5E 5KXJA 3G06A 4AKRB 5AQIB 2MOZA 3N9OA 4A5XA 3RYFE 2P9BA 4OX9T 3PUXF 4TWHA 3AAIA 3UUNA 3Q5EA 2LSJA 3NKZA 3QUJA 2W66A 3RYCE 3CMLA 5DJQC 3RF1A 4DV6T 3ONJA 2XAFB 4X66T 2BKOA 3KV9A 4ZOLE 1OEDC 4A97A 5LNKA 1R8IA 3A7MA 3RQUA 2LSKA 1YW0A 3EUHA 3GMIA 3P4SA 1OWAA 2B1EA 2Z6EA 2A72A 2VK9A 1W0AA 2C5JA 2DLRA 2LSIA 5FY1A 3RYIE 2NTXA 1HX8A 5FL0A 1KNPA 2YOEA 3V5SA 4DV3T 2LE8A 4QH1A 5DABA 2BG9A 4LF7T 4ANJA 2L3LA 3RKGA 5BR8T 5AQPB 3ZMTB 2I0MA 3AECA 3ZN1B 1YQ4A 3AE6A 1KFYA 2EHOC 4BA9A 5L3FB 2NP9A 2BZBA 1JNRA 4HN9A 4I4TE 4XBFB 4U2YA 4YLHA 3E0ZA 4HKAA 3PDYA 3L39A 3J9X1 3TKLB 4UF0B 4UR9A 4J2CA 3VRAA 5HXSA 3B5MA 4UV8B 4MALA 4H9QC 1NEKA 2E9XC 1IJ6A 1J5WA 3VKGA 1S35A 3NRYA 5C2TA 3MACA 2BG9B 4QX8B 2H7VC 4YTMA 5ABHA 4HTEA 3ZLIA 4LF8T 2ACXA 4QXBB 3QB5K 2I6HA 2X51A 5AQFB 4MBQA 5LGUB 4HFBA 3RIAA 4DIDB 2D5UA 5HEJA 5HEGA 1KK7A 3H3AA 1UUSA 4JEUB 4O2BE 5IHYA 2QGSA 5FMNA 4ZS3A 1XNRT 1IBLT 5LHHB 1NWMX 3VKHA 4ILBA 4Z90A 4TNWA 4ILUA 4G2AA 1B7TA 2V7MA 5JVDE 2HPJA 4QH5A 3TLSA 3FZFB 1LKXA 1MMAA 1HS7A 4H9SE 2XSAA 5HYAA 4CI2B 2Y6XA 3TLTA 3I9WA 1IBMT 2WMNA 3EHZA 4XAXB 1XWMA 2XQ6A 3OYXA 1T72A 4ZXLA 3AVRA 3NZQA 1YKHB 4AXPA 3ZPOA 1NAFA 2SPCA 2XQAA 4GYRA 3AE4A 3FBZA 5JDGA 4HWIB 3SRZA 4P0AA 1MIVA 4PJMA 4EXTA 5ABFA 3CX7B 3ZT5A 1VCSA 5J0ZA 4JBWF 2KLQA 2IMLA 4DV5T 4H63H 4LF5T 3ETVA 5AQOB 4GIWA 5EK2A 4ZS2A 2VKJA 4PJNA 5CA0E 3L8RA 5JR9A 3P4QA 4KP3C 4O4JE 3EI0A 4HFCA 4EV6A 3UUXB 4L5GA 4FJOA 4WBNE 3BK9A 4LF6T 2JRKA 4KX6A 2Q9QD 5L3DB 1WYBA 4V1Av 3MXZA 3AE9A 2I59A 2XUEA 2UUBT 3M65A 1D0XA 4H63V 2W63A 3UU8A 1H7CA 3RIFA 4U72A 2J1DG 3SFEA 4CZZB 3E08A 1HFAA 4WYVA 3V5UA 4DV4T 4UVAB 2MAWA 3PUWF 3PU8A 1UGOA 3AA1B 1OEDA 2HPLA 5LYJE 2A9UA 2BBJA 1HG5A 3BQIA 2L8KA 4B3MT 4QXHB 5JREA 5AQSB 2VQET 3LK2B 5JTGA 1U5PA 2XQYA 1VOMA 2V5DA 4U7YA 4L0RA 2CRBA 4OK0A 3LJCA 2N1GA 4C90A 3JAEA 2XZEA 5LA6E 2BKPA 4AQGA 4OHFA 4YHHT 3H3MA 2BS3A 1LVFA 4DUZT 1Y64B 3AE3A 3ANWA 3CPZA 2LEHA 4E7SA 5LG3A 2EHOA 3CK6A 3DP7A 4TV9E 3C51A 4DV1T 4PJJA 4PK6A 3Q5WA 3F2EA 1SA0E 4LF9T 1HG2A 3M3ZB 2X9WA 4YT0A 2VURA 1HX1B 3PUGA 4YY3T 3ZKRA 3C4ZA 3WAKA 2UUAT 4F8HA 2IUBA 3NVOA 3RH3A 3O1HA 3TLUA 3PJAA 2DNXA 4TWDA 2CCQA 4TWFA 5HXCA 2XASB 3AEGA 2M6BA 1UCUA 2GK9A 3I0OA 2E9XA 4CI1B 3RC8A 3AE2A 1LRZA 4ADZA 2C0SA 2WZHA 3JCFA 2V5CA 4HFVA 3U3IA 2ZMAA 3RQWA 3B57A 4KMCA 4TNVA 3CQCB 2J47A 3C98B 4WZXA 4KI0F 3AEBA 1ZOYA 2XQ5A 3I9YA 4X65T 3ZT6A 2MYSA 1M7KA 3QOFA 1SE7A 3OBVE 5HXHA 2CLYC 3IHRA 3VRBA 4Q25A 5HWXA 3UFEA 4JI2T 4OYJA 4WNKA 3KBTA 4OYKA 2ODUA 4CN6A 1XMQT 1BR1A 4MHCA 5LG4A 3AAEB 2AE9A 1D1CA 2UU9T 4UXNB 1LVKA 4YSXA 1N32T 1BR4A 5KX5E 1WCRA 2YU1A 1U4QA 1KNZA 2W67A 4EAHA 3KV4A 4IDPA 4GK5E 3HKEE 1X79A 4P0BA 4JI8T 4PK4A 1HNXT 5EK4A 4IE4A 1N34T 4JYAT 2YKSA 5FY7A 3NBXX 3MJXA 2OV9A 4IL9A 3AE8A 2XAJB 2A3DA 3K8PC 3AAAB 4IE0A 4QHOA 2K24A 3ZC1A 2CHOA 3KDSE 4DV0T 1ZKEA 3I0QA 4X62T 5HXEA 3OTOT 2YDRA 2YK0A 2FJBA 3EVYA 3MA9A 2K9AA 4GKJT 2UUCT 2WDVA 2HH7A 3MK7C 3HI2A 4O4LE 3PE0A 2CMRA 3KVAA 1MIYA 3AA7B 1YD8G 2KMFA 3ZJ2A 3N9NA 2E5LT 2FJAA 4AQFC 2YN6A 1ZEEA 4U31A 3RIUA 2XAQB 5JH7E 5AQHB 4BJNA 3DJBA 2V6XA 3AE5A 2Y48B 2WB5A 2Q9QC 3HKBE 4BJMA 3ZMVB 4DMWA 5F8PA 4UEMA 3S4UA 4UVBB 4IDOA 3PUSA 3P8CD 2XJ7A 4ISTA 3AA0B 3CKDA 4IE5A 3CWZB 2KNDA 3RC3A 2W00A 5HEOA 4YFSA 2V7IA 2D0TA 3EDVA 3RHWA 3L3PA 2RP4A 4Z91A 1MMDA 4HWCA 2V7KA 3FBLA 1G73A 4IE6A 4P09A 3HA4A 2WY2A 1WYCA 3SS1A 2FUPA 3WI3A 4AIUA 3HKCE 2E2AA 5HXRA 4YJ2E 1J1JA 2F4VT 3GN5A 2LKHA 4K0KT 1I94T 2B76A 4WBOA 2JIWA 3PV0F 3T1HT 4ERRA 1WFDA 1MMNA 1L0VA 1MIWA 5FNVE 4X64T 4N78D 3FZMB 5AQQB 3FZLB 2N2NA 1DU2A 2ES0A 3N9LA 1D0ZA 3OKQA 5J2UE 1CHUA 4X1YE 3NWIA 5JDNA 2C5KT 1W09A 4KHZF 4NIQA 3VR9A 1D1BA 4HE8A 3RLFF 1Z8UA 3K3QC 4PAGA 4ZI3D 4QKNA 2WMOA 3AE1A 1SHZC 4B6XA 3UUBA 1FEWA 2V8SV 4JI7T 1XDOA 3NRXA 2J4GA 2VQFT 3Q5DA 1WLXA 2D2SA 4UIGA 2LOSA 4HFDA 2X67A 4DR3T 5LHIB 3A5XA 2XPKA 1HNWT 3GN5B 4EYYR 3KBUA 3A8YC 2CXDA 3N2GE 5FVLA 2QRXA 4LFBT 5LMNT 3PUVF 4NUVA 5FXZA 1QUUA 3LBXA 3ZN0B 3QC9A 3GA8A 4H9OC 3X1DA 1WRDA 4DBRA 2XQ4A 4L9IA 3E22E 3IF8B 1YXRA 2M67A 4EGWA 2WS3A 3VHLA 4DR6T 2ZLYA 3C4XA 2D0UA 1QSDA 4GYSA 5TAOA 4HGAA 2N9DA 2XM1A 1HTJF 2K5BB 2V7LA 3QNUA 4LMJA 2E5VA 4HWDA 4KBMB 3FHNA 3KV5A 3WAJA 1E7PA 2DL1A 1BR2A 5L4HA 2BVLA 2X66A 4U3CA 4AKHA 1ZHCA 5L2LA 1XMOT 1W0BA 2LHNA 2PG8A 2ZM6T 1GQEA 2H88A 4QWNB 4U74A 2LOPA 3AEAA 4U33A 2JQ9A 5L47A 3FXDB 4AKIA 4CQIA 5DQWA 5JDHA 4EEDA 4DNDA 2W62A 1CUNA 2JQHA 2CWYA 4MLKA 4PNIA 4TV8E 4O2AE 2UXXB 3CQXC 2CHNA 5LHGB 4DUYT 2IW5B 5FVKA 3N9MA 2BG9C 3R84B 4ASKA 5ABFB 1IBKT 3UU6A 2KWIB 1JNZA 1UURA 3BQKA 5JRCA 2CPTA 1Z0PA 3LSVA 5LCYA 4EB6E 4AKLA 3RRCA 3ZT7A 4JI5T 1T8BA 4MFRA 2NW8A 4EYUA 5ABGA 5JR9B 3QB5A 4HWFA 4Z8XA 3PUAA 4DO0A 2CM0A 2PBIA 5LJMA 4XZCA 4I43B 3Q9DA 5AQMB 2JQQA 2X9XA 1FIOA 3VU7H 3IEEA 3UQ7A 3RPUA 3C4WA 2VL0A 2CEAA 2Q9QA 2CXFA 1V9DA 4DR1T 4B3ST 4H9NC 2M6IA 3C50A 5CB4E 3N9PA 4CXYA 2DWKA 2PTFA 4JI6T 2W2UA 3HR0A 4ZZBA 4TZ4C 2WP9A 4F6RC 4IDZA 2X9YA 1OEDB 5JRCB 5F5WA 4HFIA 2V7JA 1KEYA 3FB2A 4LMKA 4JI0T 2X0YA 5L3GB 1NENA 2OA5A 2MTQA 3ONLC 2WSSV 5KMGP 3W15B 5JQGE 2YDQA 5CGMA 4IE7A 3HL6A 3N2OA 2DI4A 1XNQT 3O1JA 2UXDT 2NW7A 2ODVA 2X9HA 3LG7A 5KDMC 3RX6A 4X20E 2CBIA 2CXLA 2VASA 4PFOA 3UQ4A 4JI4T 2UXBT 3KVBA 2WWUA 2C5IT 1J5ET 2VVNA 4QXCB 2BG9E 3L09A 3ANWB 5JDLA 1IZNB 4JI1T 4JV5T 2DCFA 3Q5XA 4B3RT 2EHOB 4HEAA 4EOZB 5M4YA 3KFWX 2RA1A 4ZI3C 3ZCIA 3J7Yq 2WAUA 1AJ3A 4CN4A 3KINB 5ABEA 2CWOA 2L9QA 2K48A 4A98A 1I6ZA 2HN1A 1FMWA 2NR4A 4TN7B 2XQ9A 2E9XB 4PK5A 4NPPA 4QH4A 2XAGB 5HEHA 5AQVB 5AQKB 2W4XA 4YHJA 3CVRA 5HAXA 2LRKA 3N5LA 3LFMA 4ZHQE 2J62A 5CFBA 4K0UA 4ISSA 5HCMA 4KHPT 4G63A 1E1HB 4DMVA 5EZYE 5JDFA 2H89A 2YEVC 3B13A 2VVSA 4TUYE 4X1KE 4TX5A 4HFEA 3OJAA 4ZI2D 5LMUT 2LHRA 1HR0T 4B3TT 1D1AA 3H37A 2ZM8A 5LGTB 4M1PA 1SUMB 2WBLA 5FXXA 4HWHA 3DTOA 4NXNT 5FXVA 4EIWA 2X0HA 3GWHA 2VWAA 1YQ3A 3EDUA 5IUXA 3SOLA 1S94A 2BKNA 2LSGA 3ZMZB 5EK3A 2IDOB 5IYZE 3AVSA 1M62A 4P1NA 2KZ7B 3F31A 3T1YT 3I1AA 4DVDA 2NW9A 4ILCA 2PJQA 4FI5A 1ZV4X 2JMKA 4UF0A 3FXEB 4I55E 5AQTB 2HN2A 4JUYA 3UFGA 3AXJA 2BBHA 1X9BA 2YU2A 3P4WA 3IBPA 5LBMA 3AB3B 3ZCJA 1IJ5A 1QLBA 1XDPA 4YSZA 3OVUA 2MBGA 4H9RC 5HCJA 5LJNA 5JDMA 4DBQA 4AKGA 5C3JA 4IHJE 2QA7A 3MKDA 3PURA 3UUMA 2DWGA 2V26A 5L3BB 1FMVA 3RYHE 5A1LA 5FY0A 4DR5T 2VKDA 1UX4A 3K3OA 4O4IE 1HCIA 4BAYB 5ETWA 3EAMA 2LM2A 5LP6E 3JC6D 2XAHB 2IIUA 1Y01A 3FZHB 5L3CB 3AEDA 2PFVA 2BDEA 3AXJB 3ZSTA 2MPKA 2VKOA 3RRWA 4GKKT 1VRBA 1T7SA 3O9XA 4CI3B 4X1IE 4O4HE 5BMVE 2XTLA 5CJ5A 2W0GA 4IDQA 3ZYLA 5AQLB 5FL1A 4WW0A 4UVCB 3ZEFB 3ESLA 1WR6A 1BR0A 3LDQB 5CA1E 4YTPA 3FZKB 5E0OA 4HFHA 1YKEB 4AISA 1OEDE 2IC9A 4IL4A 1OXZA 3VR8A 3U78A 3PU3A 3JAFA 2JPFA 2R6GF 3CX6B 2WU2A 4U7IA 3LK42 3K3NA 3P50A 1MNDA 2KXPB 2XQ3A 4DR7T 1FJGT 1ZP0A 1HNZT 2LSYA 2XSBA 5LOVE 2WZIA 2OLTA 3MZKB 3PUZF 2IAKA 4IT4A 3ONXA 1MNEA 2BVMA 5LGNB 2Y8DA 5LB7B 3O1IA 2BS2A 5JDQA 4AI6A 4LMLA 4IGUA 4YTNA 2JMHA 1US7B 4LF4T 4C91A 1O3XA 2CBJA 3AE7A 3EABA 1EZ3A 3O4XE 3AA6B 3HKDE 2UXNB 3Q2MA 3LK3B 3P7IA 2JJ9A 3BQLA 2ZM0A 5LBQB 2VL8A 2V6YA 2QYWA 4IIJE 2CA5A 5IWAT 3UTKA 5AQNB 3D0TA 5AQRB 1VCTA 2CE7A 4NUUA 4PW8A 3JADA 2NOXA 4KUMB 3N2KE 2FJDA 4EEBA 5GONE 3LBXB 3R6NA 4ILAA 3K1SA 3RGLA 1W9RA 3RIUC 5J1GA 3SFDA 4DV7T 4IDNA 4CN1A 4ZI2C 4UELA 3ABVA 3NZPA 3UU5A 5C8YE 2FJEA 2XQ8A 1UK5A 4COFA 2CLYB 3IA3A 4LFAT 3SWHA 2G0UA 4PJLA 5FYMA 5L3EB 1UX5A 2IC6A 4LFCT 3OYZA 1D0YA 4GOUA 3AEEA 2X68A 3ETUA 2WQYA 5DQVA 2KWHA 2EHOD 2V6YB 4CXWA 4AQFA 2UXCT 3PTRB
chains in the Genus database with same CATH topology
3FZKB 5AQUB 5AQFB 3M3ZB 5AQNB 4HWDA 5AQHB 3FZHB 1HX1B 5AQRB 1M7KA 5AQLB 1UK5A 5AQMB 4HWIB 5AQTB 5AQOB 1I6ZA 5AQSB 2D9DA 3LDQB 5AQVB 3FZMB 5AQKB 5AQQB 3FZLB 5AQIB 1T7SA 5AQPB 1UGOA 5AQGB 3FZFB 4HWFA 1M62A 4HWCA 3A8YC 4HWHA 5AQJB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FZK B;  5AQU B;  5AQF B;  3M3Z B;  5AQN B;  4HWD A;  5AQH B;  3FZH B;  1HX1 B;  5AQR B;  1M7K A;  5AQL B;  1UK5 A;  5AQM B;  4HWI B;  5AQT B;  5AQO B;  1I6Z A;  5AQS B;  2D9D A;  3LDQ B;  5AQV B;  3FZM B;  5AQK B;  5AQQ B;  3FZL B;  5AQI B;  1T7S A;  5AQP B;  1UGO A;  5AQG B;  3FZF B;  4HWF A;  1M62 A;  4HWC A;  3A8Y C;  4HWH A;  5AQJ B; 
#chains in the Genus database with same CATH topology
 5AFU L;  2FBW A;  2WDQ A;  2H7O A;  2WU5 A;  2BS4 A;  1XZY A;  3PUQ A;  3TLV A;  1WR0 A;  2LKG A;  2AXD S;  3CX8 B;  2D9D A;  2E9X D;  2WWV A;  1MMG A;  3OPC A;  2VB6 A;  4O8S A;  5AQG B;  3PJA J;  4JLE A;  5HEU A;  1IAP A;  3UU3 A;  2JQK A;  4PFP A;  5L4E A;  4CXX A;  5J2T E;  4DR4 T;  4EZH A;  3RI5 A;  3F57 A;  5H6R B;  4YJ3 E;  5FXW A;  2W61 A;  4JI3 T;  3CQG B;  2ACZ A;  2WM9 A;  4H9P C;  4DV2 T;  2LT3 A;  4I50 E;  2YDS A;  1KNR A;  2KT9 A;  2NWB A;  3CIR A;  2KSR A;  4OFZ A;  2NTY A;  2DHR A;  4GK0 E;  3ZC0 A;  2XM2 A;  3JC6 C;  3UUL A;  2H3R A;  4E7Z A;  4QX7 B;  2XQ7 A;  1E2A A;  5H6Q B;  3P4R A;  1HF8 A;  2Q9Q B;  3ZSS A;  3C64 A;  4YXD A;  2ZM2 A;  1KF6 A;  4X5T A;  4JEH B;  3ZYM A;  3KV6 A;  5LXT E;  5AQU B;  2RPA A;  5F3J A;  4UV9 B;  2XHE B;  3N9Q A;  4I0U A;  3TLW A;  4DR2 T;  2LJL A;  3ZMS B;  2IHR 1;  2V1D B;  3ZYK A;  5AQJ B;  1T98 A;  1G8X A;  2E8I A;  1N36 T;  2HHH T;  4U2Z A;  1N33 T;  3AEF A;  2WCA A;  3ZMU B;  4NXM T;  4AQY T;  2XY8 B;  2A2F X;  2QVA A;  2X0L B;  5HWY A;  3UU4 A;  2LRL A;  5FKY A;  4EZ4 A;  3QK6 A;  4ZI7 E;  4IRE A;  3PUY F;  2KIN B;  5ADX L;  3T8O A;  2LLY A;  2YIN A;  4ZZC A;  2K3W A;  5JR9 C;  4ZEY A;  4YSY A;  2WDR A;  3RKO A;  3P4P A;  4A56 A;  2LM9 A;  3ZJ1 A;  5FP3 A;  2VKH A;  3UT5 E;  5KXJ A;  3G06 A;  4AKR B;  5AQI B;  2MOZ A;  3N9O A;  4A5X A;  3RYF E;  2P9B A;  4OX9 T;  3PUX F;  4TWH A;  3AAI A;  3UUN A;  3Q5E A;  2LSJ A;  3NKZ A;  3QUJ A;  2W66 A;  3RYC E;  3CML A;  5DJQ C;  3RF1 A;  4DV6 T;  3ONJ A;  2XAF B;  4X66 T;  2BKO A;  3KV9 A;  4ZOL E;  1OED C;  4A97 A;  5LNK A;  1R8I A;  3A7M A;  3RQU A;  2LSK A;  1YW0 A;  3EUH A;  3GMI A;  3P4S A;  1OWA A;  2B1E A;  2Z6E A;  2A72 A;  2VK9 A;  1W0A A;  2C5J A;  2DLR A;  2LSI A;  5FY1 A;  3RYI E;  2NTX A;  1HX8 A;  5FL0 A;  1KNP A;  2YOE A;  3V5S A;  4DV3 T;  2LE8 A;  4QH1 A;  5DAB A;  2BG9 A;  4LF7 T;  4ANJ A;  2L3L A;  3RKG A;  5BR8 T;  5AQP B;  3ZMT B;  2I0M A;  3AEC A;  3ZN1 B;  1YQ4 A;  3AE6 A;  1KFY A;  2EHO C;  4BA9 A;  5L3F B;  2NP9 A;  2BZB A;  1JNR A;  4HN9 A;  4I4T E;  4XBF B;  4U2Y A;  4YLH A;  3E0Z A;  4HKA A;  3PDY A;  3L39 A;  3J9X 1;  3TKL B;  4UF0 B;  4UR9 A;  4J2C A;  3VRA A;  5HXS A;  3B5M A;  4UV8 B;  4MAL A;  4H9Q C;  1NEK A;  2E9X C;  1IJ6 A;  1J5W A;  3VKG A;  1S35 A;  3NRY A;  5C2T A;  3MAC A;  2BG9 B;  4QX8 B;  2H7V C;  4YTM A;  5ABH A;  4HTE A;  3ZLI A;  4LF8 T;  2ACX A;  4QXB B;  3QB5 K;  2I6H A;  2X51 A;  5AQF B;  4MBQ A;  5LGU B;  4HFB A;  3RIA A;  4DID B;  2D5U A;  5HEJ A;  5HEG A;  1KK7 A;  3H3A A;  1UUS A;  4JEU B;  4O2B E;  5IHY A;  2QGS A;  5FMN A;  4ZS3 A;  1XNR T;  1IBL T;  5LHH B;  1NWM X;  3VKH A;  4ILB A;  4Z90 A;  4TNW A;  4ILU A;  4G2A A;  1B7T A;  2V7M A;  5JVD E;  2HPJ A;  4QH5 A;  3TLS A;  3FZF B;  1LKX A;  1MMA A;  1HS7 A;  4H9S E;  2XSA A;  5HYA A;  4CI2 B;  2Y6X A;  3TLT A;  3I9W A;  1IBM T;  2WMN A;  3EHZ A;  4XAX B;  1XWM A;  2XQ6 A;  3OYX A;  1T72 A;  4ZXL A;  3AVR A;  3NZQ A;  1YKH B;  4AXP A;  3ZPO A;  1NAF A;  2SPC A;  2XQA A;  4GYR A;  3AE4 A;  3FBZ A;  5JDG A;  4HWI B;  3SRZ A;  4P0A A;  1MIV A;  4PJM A;  4EXT A;  5ABF A;  3CX7 B;  3ZT5 A;  1VCS A;  5J0Z A;  4JBW F;  2KLQ A;  2IML A;  4DV5 T;  4H63 H;  4LF5 T;  3ETV A;  5AQO B;  4GIW A;  5EK2 A;  4ZS2 A;  2VKJ A;  4PJN A;  5CA0 E;  3L8R A;  5JR9 A;  3P4Q A;  4KP3 C;  4O4J E;  3EI0 A;  4HFC A;  4EV6 A;  3UUX B;  4L5G A;  4FJO A;  4WBN E;  3BK9 A;  4LF6 T;  2JRK A;  4KX6 A;  2Q9Q D;  5L3D B;  1WYB A;  4V1A v;  3MXZ A;  3AE9 A;  2I59 A;  2XUE A;  2UUB T;  3M65 A;  1D0X A;  4H63 V;  2W63 A;  3UU8 A;  1H7C A;  3RIF A;  4U72 A;  2J1D G;  3SFE A;  4CZZ B;  3E08 A;  1HFA A;  4WYV A;  3V5U A;  4DV4 T;  4UVA B;  2MAW A;  3PUW F;  3PU8 A;  1UGO A;  3AA1 B;  1OED A;  2HPL A;  5LYJ E;  2A9U A;  2BBJ A;  1HG5 A;  3BQI A;  2L8K A;  4B3M T;  4QXH B;  5JRE A;  5AQS B;  2VQE T;  3LK2 B;  5JTG A;  1U5P A;  2XQY A;  1VOM A;  2V5D A;  4U7Y A;  4L0R A;  2CRB A;  4OK0 A;  3LJC A;  2N1G A;  4C90 A;  3JAE A;  2XZE A;  5LA6 E;  2BKP A;  4AQG A;  4OHF A;  4YHH T;  3H3M A;  2BS3 A;  1LVF A;  4DUZ T;  1Y64 B;  3AE3 A;  3ANW A;  3CPZ A;  2LEH A;  4E7S A;  5LG3 A;  2EHO A;  3CK6 A;  3DP7 A;  4TV9 E;  3C51 A;  4DV1 T;  4PJJ A;  4PK6 A;  3Q5W A;  3F2E A;  1SA0 E;  4LF9 T;  1HG2 A;  3M3Z B;  2X9W A;  4YT0 A;  2VUR A;  1HX1 B;  3PUG A;  4YY3 T;  3ZKR A;  3C4Z A;  3WAK A;  2UUA T;  4F8H A;  2IUB A;  3NVO A;  3RH3 A;  3O1H A;  3TLU A;  3PJA A;  2DNX A;  4TWD A;  2CCQ A;  4TWF A;  5HXC A;  2XAS B;  3AEG A;  2M6B A;  1UCU A;  2GK9 A;  3I0O A;  2E9X A;  4CI1 B;  3RC8 A;  3AE2 A;  1LRZ A;  4ADZ A;  2C0S A;  2WZH A;  3JCF A;  2V5C A;  4HFV A;  3U3I A;  2ZMA A;  3RQW A;  3B57 A;  4KMC A;  4TNV A;  3CQC B;  2J47 A;  3C98 B;  4WZX A;  4KI0 F;  3AEB A;  1ZOY A;  2XQ5 A;  3I9Y A;  4X65 T;  3ZT6 A;  2MYS A;  1M7K A;  3QOF A;  1SE7 A;  3OBV E;  5HXH A;  2CLY C;  3IHR A;  3VRB A;  4Q25 A;  5HWX A;  3UFE A;  4JI2 T;  4OYJ A;  4WNK A;  3KBT A;  4OYK A;  2ODU A;  4CN6 A;  1XMQ T;  1BR1 A;  4MHC A;  5LG4 A;  3AAE B;  2AE9 A;  1D1C A;  2UU9 T;  4UXN B;  1LVK A;  4YSX A;  1N32 T;  1BR4 A;  5KX5 E;  1WCR A;  2YU1 A;  1U4Q A;  1KNZ A;  2W67 A;  4EAH A;  3KV4 A;  4IDP A;  4GK5 E;  3HKE E;  1X79 A;  4P0B A;  4JI8 T;  4PK4 A;  1HNX T;  5EK4 A;  4IE4 A;  1N34 T;  4JYA T;  2YKS A;  5FY7 A;  3NBX X;  3MJX A;  2OV9 A;  4IL9 A;  3AE8 A;  2XAJ B;  2A3D A;  3K8P C;  3AAA B;  4IE0 A;  4QHO A;  2K24 A;  3ZC1 A;  2CHO A;  3KDS E;  4DV0 T;  1ZKE A;  3I0Q A;  4X62 T;  5HXE A;  3OTO T;  2YDR A;  2YK0 A;  2FJB A;  3EVY A;  3MA9 A;  2K9A A;  4GKJ T;  2UUC T;  2WDV A;  2HH7 A;  3MK7 C;  3HI2 A;  4O4L E;  3PE0 A;  2CMR A;  3KVA A;  1MIY A;  3AA7 B;  1YD8 G;  2KMF A;  3ZJ2 A;  3N9N A;  2E5L T;  2FJA A;  4AQF C;  2YN6 A;  1ZEE A;  4U31 A;  3RIU A;  2XAQ B;  5JH7 E;  5AQH B;  4BJN A;  3DJB A;  2V6X A;  3AE5 A;  2Y48 B;  2WB5 A;  2Q9Q C;  3HKB E;  4BJM A;  3ZMV B;  4DMW A;  5F8P A;  4UEM A;  3S4U A;  4UVB B;  4IDO A;  3PUS A;  3P8C D;  2XJ7 A;  4IST A;  3AA0 B;  3CKD A;  4IE5 A;  3CWZ B;  2KND A;  3RC3 A;  2W00 A;  5HEO A;  4YFS A;  2V7I A;  2D0T A;  3EDV A;  3RHW A;  3L3P A;  2RP4 A;  4Z91 A;  1MMD A;  4HWC A;  2V7K A;  3FBL A;  1G73 A;  4IE6 A;  4P09 A;  3HA4 A;  2WY2 A;  1WYC A;  3SS1 A;  2FUP A;  3WI3 A;  4AIU A;  3HKC E;  2E2A A;  5HXR A;  4YJ2 E;  1J1J A;  2F4V T;  3GN5 A;  2LKH A;  4K0K T;  1I94 T;  2B76 A;  4WBO A;  2JIW A;  3PV0 F;  3T1H T;  4ERR A;  1WFD A;  1MMN A;  1L0V A;  1MIW A;  5FNV E;  4X64 T;  4N78 D;  3FZM B;  5AQQ B;  3FZL B;  2N2N A;  1DU2 A;  2ES0 A;  3N9L A;  1D0Z A;  3OKQ A;  5J2U E;  1CHU A;  4X1Y E;  3NWI A;  5JDN A;  2C5K T;  1W09 A;  4KHZ F;  4NIQ A;  3VR9 A;  1D1B A;  4HE8 A;  3RLF F;  1Z8U A;  3K3Q C;  4PAG A;  4ZI3 D;  4QKN A;  2WMO A;  3AE1 A;  1SHZ C;  4B6X A;  3UUB A;  1FEW A;  2V8S V;  4JI7 T;  1XDO A;  3NRX A;  2J4G A;  2VQF T;  3Q5D A;  1WLX A;  2D2S A;  4UIG A;  2LOS A;  4HFD A;  2X67 A;  4DR3 T;  5LHI B;  3A5X A;  2XPK A;  1HNW T;  3GN5 B;  4EYY R;  3KBU A;  3A8Y C;  2CXD A;  3N2G E;  5FVL A;  2QRX A;  4LFB T;  5LMN T;  3PUV F;  4NUV A;  5FXZ A;  1QUU A;  3LBX A;  3ZN0 B;  3QC9 A;  3GA8 A;  4H9O C;  3X1D A;  1WRD A;  4DBR A;  2XQ4 A;  4L9I A;  3E22 E;  3IF8 B;  1YXR A;  2M67 A;  4EGW A;  2WS3 A;  3VHL A;  4DR6 T;  2ZLY A;  3C4X A;  2D0U A;  1QSD A;  4GYS A;  5TAO A;  4HGA A;  2N9D A;  2XM1 A;  1HTJ F;  2K5B B;  2V7L A;  3QNU A;  4LMJ A;  2E5V A;  4HWD A;  4KBM B;  3FHN A;  3KV5 A;  3WAJ A;  1E7P A;  2DL1 A;  1BR2 A;  5L4H A;  2BVL A;  2X66 A;  4U3C A;  4AKH A;  1ZHC A;  5L2L A;  1XMO T;  1W0B A;  2LHN A;  2PG8 A;  2ZM6 T;  1GQE A;  2H88 A;  4QWN B;  4U74 A;  2LOP A;  3AEA A;  4U33 A;  2JQ9 A;  5L47 A;  3FXD B;  4AKI A;  4CQI A;  5DQW A;  5JDH A;  4EED A;  4DND A;  2W62 A;  1CUN A;  2JQH A;  2CWY A;  4MLK A;  4PNI A;  4TV8 E;  4O2A E;  2UXX B;  3CQX C;  2CHN A;  5LHG B;  4DUY T;  2IW5 B;  5FVK A;  3N9M A;  2BG9 C;  3R84 B;  4ASK A;  5ABF B;  1IBK T;  3UU6 A;  2KWI B;  1JNZ A;  1UUR A;  3BQK A;  5JRC A;  2CPT A;  1Z0P A;  3LSV A;  5LCY A;  4EB6 E;  4AKL A;  3RRC A;  3ZT7 A;  4JI5 T;  1T8B A;  4MFR A;  2NW8 A;  4EYU A;  5ABG A;  5JR9 B;  3QB5 A;  4HWF A;  4Z8X A;  3PUA A;  4DO0 A;  2CM0 A;  2PBI A;  5LJM A;  4XZC A;  4I43 B;  3Q9D A;  5AQM B;  2JQQ A;  2X9X A;  1FIO A;  3VU7 H;  3IEE A;  3UQ7 A;  3RPU A;  3C4W A;  2VL0 A;  2CEA A;  2Q9Q A;  2CXF A;  1V9D A;  4DR1 T;  4B3S T;  4H9N C;  2M6I A;  3C50 A;  5CB4 E;  3N9P A;  4CXY A;  2DWK A;  2PTF A;  4JI6 T;  2W2U A;  3HR0 A;  4ZZB A;  4TZ4 C;  2WP9 A;  4F6R C;  4IDZ A;  2X9Y A;  1OED B;  5JRC B;  5F5W A;  4HFI A;  2V7J A;  1KEY A;  3FB2 A;  4LMK A;  4JI0 T;  2X0Y A;  5L3G B;  1NEN A;  2OA5 A;  2MTQ A;  3ONL C;  2WSS V;  5KMG P;  3W15 B;  5JQG E;  2YDQ A;  5CGM A;  4IE7 A;  3HL6 A;  3N2O A;  2DI4 A;  1XNQ T;  3O1J A;  2UXD T;  2NW7 A;  2ODV A;  2X9H A;  3LG7 A;  5KDM C;  3RX6 A;  4X20 E;  2CBI A;  2CXL A;  2VAS A;  4PFO A;  3UQ4 A;  4JI4 T;  2UXB T;  3KVB A;  2WWU A;  2C5I T;  1J5E T;  2VVN A;  4QXC B;  2BG9 E;  3L09 A;  3ANW B;  5JDL A;  1IZN B;  4JI1 T;  4JV5 T;  2DCF A;  3Q5X A;  4B3R T;  2EHO B;  4HEA A;  4EOZ B;  5M4Y A;  3KFW X;  2RA1 A;  4ZI3 C;  3ZCI A;  3J7Y q;  2WAU A;  1AJ3 A;  4CN4 A;  3KIN B;  5ABE A;  2CWO A;  2L9Q A;  2K48 A;  4A98 A;  1I6Z A;  2HN1 A;  1FMW A;  2NR4 A;  4TN7 B;  2XQ9 A;  2E9X B;  4PK5 A;  4NPP A;  4QH4 A;  2XAG B;  5HEH A;  5AQV B;  5AQK B;  2W4X A;  4YHJ A;  3CVR A;  5HAX A;  2LRK A;  3N5L A;  3LFM A;  4ZHQ E;  2J62 A;  5CFB A;  4K0U A;  4ISS A;  5HCM A;  4KHP T;  4G63 A;  1E1H B;  4DMV A;  5EZY E;  5JDF A;  2H89 A;  2YEV C;  3B13 A;  2VVS A;  4TUY E;  4X1K E;  4TX5 A;  4HFE A;  3OJA A;  4ZI2 D;  5LMU T;  2LHR A;  1HR0 T;  4B3T T;  1D1A A;  3H37 A;  2ZM8 A;  5LGT B;  4M1P A;  1SUM B;  2WBL A;  5FXX A;  4HWH A;  3DTO A;  4NXN T;  5FXV A;  4EIW A;  2X0H A;  3GWH A;  2VWA A;  1YQ3 A;  3EDU A;  5IUX A;  3SOL A;  1S94 A;  2BKN A;  2LSG A;  3ZMZ B;  5EK3 A;  2IDO B;  5IYZ E;  3AVS A;  1M62 A;  4P1N A;  2KZ7 B;  3F31 A;  3T1Y T;  3I1A A;  4DVD A;  2NW9 A;  4ILC A;  2PJQ A;  4FI5 A;  1ZV4 X;  2JMK A;  4UF0 A;  3FXE B;  4I55 E;  5AQT B;  2HN2 A;  4JUY A;  3UFG A;  3AXJ A;  2BBH A;  1X9B A;  2YU2 A;  3P4W A;  3IBP A;  5LBM A;  3AB3 B;  3ZCJ A;  1IJ5 A;  1QLB A;  1XDP A;  4YSZ A;  3OVU A;  2MBG A;  4H9R C;  5HCJ A;  5LJN A;  5JDM A;  4DBQ A;  4AKG A;  5C3J A;  4IHJ E;  2QA7 A;  3MKD A;  3PUR A;  3UUM A;  2DWG A;  2V26 A;  5L3B B;  1FMV A;  3RYH E;  5A1L A;  5FY0 A;  4DR5 T;  2VKD A;  1UX4 A;  3K3O A;  4O4I E;  1HCI A;  4BAY B;  5ETW A;  3EAM A;  2LM2 A;  5LP6 E;  3JC6 D;  2XAH B;  2IIU A;  1Y01 A;  3FZH B;  5L3C B;  3AED A;  2PFV A;  2BDE A;  3AXJ B;  3ZST A;  2MPK A;  2VKO A;  3RRW A;  4GKK T;  1VRB A;  1T7S A;  3O9X A;  4CI3 B;  4X1I E;  4O4H E;  5BMV E;  2XTL A;  5CJ5 A;  2W0G A;  4IDQ A;  3ZYL A;  5AQL B;  5FL1 A;  4WW0 A;  4UVC B;  3ZEF B;  3ESL A;  1WR6 A;  1BR0 A;  3LDQ B;  5CA1 E;  4YTP A;  3FZK B;  5E0O A;  4HFH A;  1YKE B;  4AIS A;  1OED E;  2IC9 A;  4IL4 A;  1OXZ A;  3VR8 A;  3U78 A;  3PU3 A;  3JAF A;  2JPF A;  2R6G F;  3CX6 B;  2WU2 A;  4U7I A;  3LK4 2;  3K3N A;  3P50 A;  1MND A;  2KXP B;  2XQ3 A;  4DR7 T;  1FJG T;  1ZP0 A;  1HNZ T;  2LSY A;  2XSB A;  5LOV E;  2WZI A;  2OLT A;  3MZK B;  3PUZ F;  2IAK A;  4IT4 A;  3ONX A;  1MNE A;  2BVM A;  5LGN B;  2Y8D A;  5LB7 B;  3O1I A;  2BS2 A;  5JDQ A;  4AI6 A;  4LML A;  4IGU A;  4YTN A;  2JMH A;  1US7 B;  4LF4 T;  4C91 A;  1O3X A;  2CBJ A;  3AE7 A;  3EAB A;  1EZ3 A;  3O4X E;  3AA6 B;  3HKD E;  2UXN B;  3Q2M A;  3LK3 B;  3P7I A;  2JJ9 A;  3BQL A;  2ZM0 A;  5LBQ B;  2VL8 A;  2V6Y A;  2QYW A;  4IIJ E;  2CA5 A;  5IWA T;  3UTK A;  5AQN B;  3D0T A;  5AQR B;  1VCT A;  2CE7 A;  4NUU A;  4PW8 A;  3JAD A;  2NOX A;  4KUM B;  3N2K E;  2FJD A;  4EEB A;  5GON E;  3LBX B;  3R6N A;  4ILA A;  3K1S A;  3RGL A;  1W9R A;  3RIU C;  5J1G A;  3SFD A;  4DV7 T;  4IDN A;  4CN1 A;  4ZI2 C;  4UEL A;  3ABV A;  3NZP A;  3UU5 A;  5C8Y E;  2FJE A;  2XQ8 A;  1UK5 A;  4COF A;  2CLY B;  3IA3 A;  4LFA T;  3SWH A;  2G0U A;  4PJL A;  5FYM A;  5L3E B;  1UX5 A;  2IC6 A;  4LFC T;  3OYZ A;  1D0Y A;  4GOU A;  3AEE A;  2X68 A;  3ETU A;  2WQY A;  5DQV A;  2KWH A;  2EHO D;  2V6Y B;  4CXW A;  4AQF A;  2UXC T;  3PTR B; 
#chains in the Genus database with same CATH homology
 3FZK B;  5AQU B;  5AQF B;  3M3Z B;  5AQN B;  4HWD A;  5AQH B;  3FZH B;  1HX1 B;  5AQR B;  1M7K A;  5AQL B;  1UK5 A;  5AQM B;  4HWI B;  5AQT B;  5AQO B;  1I6Z A;  5AQS B;  2D9D A;  3LDQ B;  5AQV B;  3FZM B;  5AQK B;  5AQQ B;  3FZL B;  5AQI B;  1T7S A;  5AQP B;  1UGO A;  5AQG B;  3FZF B;  4HWF A;  1M62 A;  4HWC A;  3A8Y C;  4HWH A;  5AQJ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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