5AQJB

Fragment-based screening of hsp70 sheds light on the functional role of atp-binding site residues
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
114
structure length
114
Chain Sequence
PLGSNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
pubmed doi rcsb
molecule tags Chaperone
source organism Homo sapiens
molecule keywords HEAT SHOCK COGNATE 71 KDA PROTEIN
total genus 46
structure length 114
sequence length 114
chains with identical sequence D, F
ec nomenclature
pdb deposition date 2015-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02179 BAG BAG domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.58.120 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase; Chain G, domain 1 BAG domain 5aqjB00
3FZHB 5AQUB 5AQFB 5AQPB 5AQRB 1M62A 2D9DA 5AQVB 4HWFA 3FZFB 3FZLB 5AQGB 5AQTB 4HWIB 1UGOA 5AQOB 1HX1B 3FZMB 5AQLB 3FZKB 5AQHB 5AQJB 3LDQB 5AQMB 5AQQB 5AQIB 5AQKB 1T7SA 3M3ZB 1I6ZA 4HWCA 5AQSB 5AQNB 4HWDA 4HWHA 1UK5A 1M7KA 3A8YC
chains in the Genus database with same CATH superfamily
3KBTA 5AQPB 3VR9A 2CLYB 5AQRB 3JCFA 1IJ6A 3VKGA 4EIWA 1I94T 1D0XA 3OTOT 3IHRA 2KXPB 3PU3A 2BS4A 2BBHA 1IAPA 2WMOA 2KMFA 2WDVA 3FXDB 5ABFA 3RQWA 4V1Av 5LBQB 2DCFA 3B13A 4JYAT 1YQ4A 4X1YE 3IA3A 2FJBA 4LF8T 1HX1B 4X5TA 5ABEA 1E1HB 2WBLA 3EHZA 3CQXC 3WAJA 2YU1A 4ILBA 4F6RC 3T8OA 2WP9A 3P7IA 2XHEB 3GN5A 2NR4A 3LFMA 3LG7A 4UV9B 2VKHA 3JC6C 5HEGA 1MNEA 3AEFA 2UUBT 4DR7T 5JR9A 4DV1T 4KMCA 1XDPA 3AVRA 3CX6B 4HFHA 4MLKA 3RH3A 1MMGA 5JQGE 3SWHA 2A9UA 5AQHB 5AQMB 1D0ZA 3RLFF 1Z8UA 2X0YA 3AEBA 2M6IA 5C3JA 1MMNA 5CFBA 4X20E 4ASKA 4EXTA 3LSVA 2J62A 4J2CA 3RIFA 5C2TA 2RPAA 2M67A 5LHIB 2XQ7A 3B57A 2UUAT 2KSRA 3KVAA 2H3RA 2YOEA 4UVAB 2LKGA 3KDSE 2NTXA 5LP6E 5LXTE 3PUQA 4X1KE 4HN9A 1AJ3A 3ESLA 5ABGA 3KVBA 4HFBA 3JC6D 4P0BA 3AB3B 2D2SA 2IDOB 3ZJ1A 3EAMA 3LK2B 1HG2A 3HL6A 3PUSA 4IL9A 2W66A 2X51A 3N9NA 2C5JA 4QX8B 2KWIB 3IBPA 2WZIA 2UXDT 3LDQB 3QB5A 3SFEA 2BS3A 4UELA 3W15B 3R84B 1S35A 3R6NA 2MYSA 3AA0B 4IDOA 2XASB 4AKRB 2WZHA 1JNZA 4ZOLE 3AA1B 1UUSA 3FB2A 4NUUA 3F57A 2DI4A 3AE4A 3ZYMA 5IUXA 2VVNA 3CK6A 4TUYE 5L47A 3CIRA 2CXDA 4LF7T 2BG9A 1XWMA 2XQAA 4TV9E 2JRKA 5FXWA 3EI0A 2PJQA 5DABA 3ZSTA 2JQQA 4GYSA 1ZV4X 3PE0A 4KX6A 3ZC0A 2MOZA 4JEHB 4E7ZA 5L3EB 4L9IA 5LBMA 1JNRA 4TNWA 3OYZA 5L4EA 5DJQC 5C8YE 1E2AA 4U72A 2CA5A 3ZC1A 1SHZC 3UFGA 3PUVF 1UURA 2CXLA 1BR2A 2ES0A 4F8HA 4ILCA 5HEJA 4QXCB 3AAEB 2R6GF 5F8PA 2Y8DA 4EYUA 1MIWA 2LM2A 3NWIA 3PTRB 4PNIA 4HEAA 5IYZE 5LCYA 3K3NA 5LJMA 2BVLA 4BA9A 2N1GA 3GA8A 3UTKA 3HR0A 3Q5EA 4IDZA 5HAXA 3FHNA 5LNKA 4O2BE 2I6HA 1WCRA 4LF5T 4TNVA 4PW8A 5FXVA 5AQFB 4C90A 3ZT5A 4FJOA 3UQ4A 1MNDA 2XM2A 2DL1A 4GOUA 3RC3A 4C91A 4DO0A 4JBWF 5KXJA 5J1GA 4LMKA 2XM1A 4Z90A 5FXXA 4P0AA 3UQ7A 2WQYA 3AEEA 3I0QA 4PK4A 3M65A 3HI2A 4YTNA 3MJXA 1Z0PA 5JVDE 2K3WA 4DR4T 4U74A 5CB4E 2X0LB 3VRBA 3Q9DA 5L3GB 2YEVC 4CN6A 5LOVE 3RF1A 2ZLYA 4HWIB 2CBIA 4GK0E 5DQWA 3PJAA 4Z91A 3BQLA 2BS2A 5J2TE 5HYAA 4NIQA 2BBJA 3P8CD 5J2UE 3L8RA 3KV5A 1WLXA 3RYFE 2VQET 4PFPA 4DMVA 4QHOA 5JRCA 4ZI2C 2WAUA 4JI7T 3PU8A 1XMOT 4DR2T 4O2AE 2DHRA 3ZYLA 2CEAA 3RYHE 4HFVA 1YXRA 4TZ4C 2XY8B 2DWGA 1D1CA 4I50E 5L3DB 1OWAA 3GWHA 3FZLB 3N2GE 3P50A 2LT3A 2W61A 3ZMUB 2E9XC 2F4VT 3KV4A 3N9QA 1WR6A 5TAOA 2LSYA 3Q5DA 2DWKA 3QK6A 1VOMA 3J9X1 3FZKB 3CWZB 4AKGA 4NXNT 4UV8B 3AXJA 2D9DA 4N78D 4B3RT 4A97A 4AXPA 1U5PA 2SPCA 4YSZA 2LE8A 2VL0A 4LFCT 3UU4A 4CXYA 3C64A 2QVAA 1XNRT 2W67A 2JQ9A 3OJAA 3N2KE 4I4TE 2LRKA 3PUWF 3VKHA 4QXBB 3AEDA 2HPJA 3KINB 4DMWA 2EHOA 2BKPA 2KLQA 4B3TT 1WR0A 2C0SA 4U33A 3L39A 2P9BA 1M7KA 3A8YC 4YY3T 3CQCB 5JDGA 2M6BA 1OEDB 2YDSA 4H9OC 4UVBB 4ZZBA 5JDNA 5AQLB 1CHUA 2NW9A 3N9PA 2C5IT 2VQFT 4ZXLA 2PTFA 3G06A 2C5KT 4HWHA 5FYMA 2YU2A 1ZEEA 5ABHA 3ZYKA 4YSXA 5A1LA 3VHLA 4CZZB 4DV0T 5AQTB 2XQ9A 5LMNT 4X64T 5LHHB 4IDQA 2EHOC 1B7TA 4GKJT 5HXCA 4YLHA 1QUUA 4NXMT 5HEUA 3SS1A 2CLYC 5JDFA 4HKAA 3RYCE 4KHZF 3NZPA 2XQ3A 1KNZA 2AE9A 4JI5T 1IJ5A 4DBQA 2UXXB 4TN7B 3WI3A 3UUNA 5HXHA 4IL4A 4UIGA 3EVYA 1V9DA 3KV6A 3AAIA 2NW7A 5EK3A 1Y01A 4AQFA 5AQJB 2QRXA 1FIOA 4AKLA 3UT5E 4HWCA 2XTLA 2A3DA 2YDQA 5AQUB 2X9YA 3E0ZA 4ZEYA 1YQ3A 4IDPA 4HGAA 3K1SA 3K3QC 5LB7B 5AQQB 1ZHCA 5AQKB 2CM0A 1BR1A 2LOSA 2EHOD 3ZCJA 4H9QC 5HXRA 2CE7A 5ETWA 5M4YA 2CRBA 5AQOB 3AE7A 4JI6T 5L3BB 2VURA 3UUBA 1IZNB 3RIAA 5HCMA 4YHJA 4HWFA 3GN5B 4DR3T 3P4PA 4OK0A 2LKHA 5E0OA 4AQFC 3I9YA 4QWNB 1I6ZA 3SRZA 4AISA 3RRCA 3AEAA 3BQKA 5JR9C 3AE8A 4DUYT 1WRDA 1N33T 3UUXB 2W63A 2WU2A 3BQIA 4ERRA 2CCQA 4DV2T 3ZEFB 4YXDA 5JDHA 2K9AA 1N32T 2VB6A 2LHNA 4CQIA 4B6XA 1W0BA 2CBJA 2JIWA 2JJ9A 4CI3B 4AKIA 1VCTA 4A98A 2UXNB 5FL1A 1FJGT 1WFDA 4M1PA 2MPKA 3MKDA 1KK7A 4QXHB 4DR6T 4X65T 1HR0T 2X67A 4H63H 3U3IA 1W9RA 3E22E 1US7B 2HN1A 4JI4T 3RX6A 4YT0A 4HFDA 5LG3A 4ADZA 3PUYF 2Q9QB 1T72A 3EUHA 3NRYA 4PJLA 2HH7A 1X79A 3FBZA 4FI5A 5BMVE 3F2EA 4HFEA 3EDVA 3PDYA 2X68A 2OA5A 1HNWT 2XQ6A 3CQGB 2XSAA 1OXZA 4QH4A 1UX4A 3NBXX 4DV4T 1OEDE 2V7JA 3UU3A 2UXBT 4ANJA 4ZI7E 2X0HA 5L3CB 1XMQT 2NWBA 2V7IA 3CX8B 4MALA 1S94A 4IE0A 1N34T 2XAJB 2PBIA 5AQSB 2QYWA 4G2AA 4PJJA 5LGUB 1FMVA 2FJAA 3N9OA 2QA7A 3L09A 4H9SE 3SOLA 3IF8B 1MMAA 2BG9C 3ONLC 4KHPT 3NVOA 2I0MA 3ZT7A 4JV5T 3JAEA 3ZLIA 5HWYA 4IE7A 5JTGA 3RGLA 3ZCIA 1D0YA 4KUMB 1L0VA 2V6YB 2WMNA 1VCSA 5KMGP 1H7CA 3PJAJ 5H6RB 3TLVA 1QLBA 2LSJA 4EGWA 3QB5K 2KT9A 1HFAA 4DUZT 4AQYT 2OV9A 4H63V 3LBXB 2BKNA 4U31A 2HPLA 4GIWA 1HNZT 4BJMA 3ZN0B 3ZPOA 3HKBE 4LF9T 2B76A 4TV8E 1YKHB 4IREA 3CVRA 3ZN1B 5AFUL 3PUXF 1FEWA 2H88A 4ZZCA 3CPZA 5EK2A 5LGNB 3U78A 2BKOA 2ODUA 2KINB 3VRAA 1SA0E 3LJCA 3A5XA 3D0TA 2UXCT 5LGTB 2JPFA 2JQKA 4DBRA 1UX5A 3O4XE 4IE4A 3I0OA 3UU8A 2CWOA 4LMLA 4L0RA 4YJ3E 3RQUA 4I0UA 3RYIE 2E5LT 5F5WA 2XAGB 3TLUA 3WAKA 1W09A 5LHGB 3ZMSB 3Q5XA 2L8KA 3FZHB 2ZM8A 2FUPA 1IBKT 2K5BB 1J5ET 4CN4A 3UU6A 5IHYA 3FZFB 4EEBA 1UGOA 4KP3C 1FMWA 5F3JA 4DIDB 4UF0A 4U2ZA 3I1AA 2G0UA 4BAYB 4WYVA 2IUBA 3FXEB 5L4HA 2ACXA 2V5DA 3DP7A 3T1HT 2GK9A 4GK5E 5LG4A 2MBGA 3ZKRA 5FL0A 1YKEB 3P4RA 3HKCE 4DR1T 3ABVA 2E9XB 2VWAA 4EEDA 2BVMA 4JEUB 4UEMA 2CMRA 2CXFA 4KI0F 2RP4A 1CUNA 3RI5A 3BK9A 4JUYA 3E08A 3EABA 5JREA 2JMHA 4DVDA 3MK7C 3AA7B 4TWFA 4AKHA 2IW5B 1KF6A 4AIUA 1LKXA 3B5MA 5LYJE 4B3ST 4JI8T 5AQIB 3C50A 3AAAB 3O1IA 3TLWA 3LK3B 4PJMA 3F31A 5CA1E 1LVKA 5H6QB 2UU9T 4U7IA 3ANWA 3IEEA 3J7Yq 3QNUA 2LM9A 2N2NA 4CXWA 4XZCA 2J1DG 4CXXA 3JADA 2VL8A 4MFRA 4ILAA 3ZT6A 2E2AA 1LVFA 4JI2T 3PUAA 1E7PA 2XQ4A 3AXJB 5JDMA 4HE8A 3MXZA 2LHRA 3RRWA 1O3XA 1DU2A 2ACZA 4MHCA 2YKSA 3MACA 5AQVB 1G73A 3ETUA 1HF8A 3NKZA 2PFVA 2V7MA 2W62A 1NAFA 2A72A 4GYRA 4HWDA 3RIUA 2ZM2A 2XJ7A 2YN6A 3CKDA 2H7VC 4KBMB 2Y48B 3HKDE 4BJNA 3I9WA 2E5VA 4OFZA 4O4LE 3UULA 3PURA 4B3MT 5FY1A 1D1AA 1N36T 2LRLA 2VKJA 4JI3T 4LF6T 5IWAT 2VKOA 3HA4A 3ZSSA 1NWMX 2QGSA 4I43B 2H7OA 5JH7E 2NW8A 3JAFA 3X1DA 1SUMB 3AVSA 2XZEA 3C4XA 4K0KT 5EK4A 3FBLA 3Q2MA 2DNXA 2LSGA 4NUVA 2XQ5A 5FXZA 5ABFB 3AE5A 1Y64B 4IGUA 4OYKA 1IBMT 3RIUC 2VVSA 1BR4A 2XPKA 4DR5T 4CN1A 2WWUA 3P4WA 4WZXA 5FVKA 2WDQA 1ZKEA 3AE2A 4JI0T 4AQGA 3ZJ2A 1KFYA 4UR9A 2Z6EA 4IE6A 3K3OA 1M62A 5HEOA 4Z8XA 1HCIA 3ZMVB 1IBLT 1NENA 4LMJA 2CPTA 3OVUA 4PJNA 2DLRA 4ZS3A 4E7SA 1KNRA 1UK5A 2ODVA 3RC8A 2PG8A 5JR9B 1YD8G 4YJ2E 4G63A 5FNVE 4QKNA 1W0AA 2FBWA 2LLYA 4OYJA 4P1NA 1X9BA 2MTQA 3N5LA 2LJLA 3TLSA 3MZKB 4U2YA 1D1BA 5FMNA 4UXNB 3UU5A 2Q9QA 2W00A 2VK9A 2V6XA 3AE1A 2IHR1 4JI1T 3K8PC 1G8XA 4O8SA 3H3MA 5HXEA 4YSYA 3CMLA 2XSBA 5CJ5A 3KV9A 2J4GA 2XAQB 3SFDA 2W0GA 4COFA 3A7MA 3AE3A 4U7YA 5HWXA 4EZHA 2OLTA 1R8IA 5ADXL 4CI2B 3O1HA 4TWDA 5HXSA 4QH5A 2NP9A 4Q25A 2VKDA 4O4HE 2YDRA 5AQGB 2I59A 4QX7B 2CWYA 3FZMB 3H3AA 4UVCB 5BR8T 3N9LA 2IC9A 2Q9QC 3HKEE 1XDOA 4EYYR 2ZM0A 4XBFB 2VASA 2JMKA 4I55E 4U3CA 3EDUA 2UUCT 1HX8A 4YFSA 1T7SA 4WNKA 1MIVA 2HN2A 3AEGA 4OHFA 4L5GA 3DTOA 2BDEA 2V6YA 4WBOA 2B1EA 3QOFA 2BG9B 3N2OA 1J1JA 2KNDA 3RKOA 3O9XA 3OYXA 4DNDA 2YINA 4EV6A 3VU7H 4X1IE 5CA0E 3LBXA 2D0TA 2K24A 2FJDA 2V7LA 1KNPA 5HEHA 2WSSV 2IIUA 3AECA 3RKGA 1MMDA 3TLTA 3KBUA 3P4QA 4X62T 4LF4T 4DV6T 2RA1A 4WW0A 2Q9QD 4TX5A 3KFWX 5HCJA 3PUZF 4HTEA 4YTPA 3QUJA 2AXDS 2V8SV 4EOZB 4HFCA 2HHHT 3C98B 3GMIA 2IC6A 2XUEA 1ZP0A 2NTYA 5FP3A 3H37A 2X9WA 2A2FX 4ISTA 4JLEA 2V1DB 2D5UA 2V7KA 3N9MA 3QC9A 2YK0A 3RPUA 5J0ZA 4IDNA 3ONXA 4O4IE 4A56A 2H89A 2CHOA 4IHJE 1GQEA 1XZYA 1UCUA 2LSIA 2X9HA 4DV7T 1SE7A 2XQYA 3V5UA 4PK5A 5FY0A 3PV0F 5FKYA 1ZOYA 3CX7B 3Q5WA 3T1YT 2CHNA 4A5XA 2KZ7B 4PFOA 1LRZA 4LFAT 3C4ZA 3O1JA 1HG5A 3AE9A 3V5SA 2BZBA 3PUGA 2WM9A 2E9XA 2JQHA 3UUMA 4AI6A 1QSDA 2W4XA 1KEYA 3ZMZB 5AQNB 2FJEA 3OPCA 3L3PA 1T98A 4GKKT 2V26A 3ETVA 5JDLA 5LMUT 4ZS2A 2WU5A 3OKQA 3UFEA 5LJNA 3NZQA 2LEHA 3M3ZB 2V5CA 4ISSA 4CI1B 1XNQT 4H9NC 2XAFB 4IIJE 2WCAA 5EZYE 1WYBA 2J47A 2XQ8A 2X66A 4K0UA 3AE6A 2E8IA 5JRCB 1NEKA 4TWHA 2IAKA 5KDMC 1HTJF 4EZ4A 4UF0B 1U4QA 1HNXT 2XAHB 4H9PC 2ZMAA 2NOXA 1VRBA 4DV5T 3LK42 4H9RC 4HFIA 4ZI3C 4OX9T 4P09A 5CGMA 1BR0A 4EB6E 2WY2A 5KX5E 5JDQA 1HS7A 4ZHQE 1EZ3A 3C4WA 3DJBA 4LFBT 4X66T 5DQVA 4MBQA 2X9XA 5L3FB 2K48A 4WBNE 4IE5A 2MAWA 2L3LA 1T8BA 4O4JE 1OEDA 2WWVA 2WDRA 3VR8A 4ZI2D 3S4UA 4ILUA 2WB5A 2W2UA 2N9DA 2LSKA 1J5WA 2WS3A 4QH1A 2LOPA 2ZM6T 2BG9E 4NPPA 4PK6A 2L9QA 3ZMTB 3ONJA 1YW0A 4YTMA 2KWHA 5FVLA 5FY7A 2E9XD 3C51A 2Y6XA 5L2LA 4IT4A 4PAGA 3RHWA 3P4SA 3AA6B 4DV3T 4ZI3D 4YHHT 1OEDC 1WYCA 2IMLA 5LA6E 2D0UA 4XAXB 1MIYA 3OBVE 4EAHA 3ANWB 5GONE 2EHOB 3TKLB 3MA9A 3NRXA
chains in the Genus database with same CATH topology
3FZHB 5AQUB 5AQFB 5AQPB 5AQRB 1M62A 2D9DA 5AQVB 4HWFA 3FZFB 3FZLB 5AQGB 5AQTB 4HWIB 1UGOA 5AQOB 1HX1B 3FZMB 5AQLB 3FZKB 5AQHB 5AQJB 3LDQB 5AQMB 5AQQB 5AQIB 5AQKB 1T7SA 3M3ZB 1I6ZA 4HWCA 5AQSB 5AQNB 4HWDA 4HWHA 1UK5A 1M7KA 3A8YC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FZH B;  5AQU B;  5AQF B;  5AQP B;  5AQR B;  1M62 A;  2D9D A;  5AQV B;  4HWF A;  3FZF B;  3FZL B;  5AQG B;  5AQT B;  4HWI B;  1UGO A;  5AQO B;  1HX1 B;  3FZM B;  5AQL B;  3FZK B;  5AQH B;  5AQJ B;  3LDQ B;  5AQM B;  5AQQ B;  5AQI B;  5AQK B;  1T7S A;  3M3Z B;  1I6Z A;  4HWC A;  5AQS B;  5AQN B;  4HWD A;  4HWH A;  1UK5 A;  1M7K A;  3A8Y C; 
#chains in the Genus database with same CATH topology
 3KBT A;  5AQP B;  3VR9 A;  2CLY B;  5AQR B;  3JCF A;  1IJ6 A;  3VKG A;  4EIW A;  1I94 T;  1D0X A;  3OTO T;  3IHR A;  2KXP B;  3PU3 A;  2BS4 A;  2BBH A;  1IAP A;  2WMO A;  2KMF A;  2WDV A;  3FXD B;  5ABF A;  3RQW A;  4V1A v;  5LBQ B;  2DCF A;  3B13 A;  4JYA T;  1YQ4 A;  4X1Y E;  3IA3 A;  2FJB A;  4LF8 T;  1HX1 B;  4X5T A;  5ABE A;  1E1H B;  2WBL A;  3EHZ A;  3CQX C;  3WAJ A;  2YU1 A;  4ILB A;  4F6R C;  3T8O A;  2WP9 A;  3P7I A;  2XHE B;  3GN5 A;  2NR4 A;  3LFM A;  3LG7 A;  4UV9 B;  2VKH A;  3JC6 C;  5HEG A;  1MNE A;  3AEF A;  2UUB T;  4DR7 T;  5JR9 A;  4DV1 T;  4KMC A;  1XDP A;  3AVR A;  3CX6 B;  4HFH A;  4MLK A;  3RH3 A;  1MMG A;  5JQG E;  3SWH A;  2A9U A;  5AQH B;  5AQM B;  1D0Z A;  3RLF F;  1Z8U A;  2X0Y A;  3AEB A;  2M6I A;  5C3J A;  1MMN A;  5CFB A;  4X20 E;  4ASK A;  4EXT A;  3LSV A;  2J62 A;  4J2C A;  3RIF A;  5C2T A;  2RPA A;  2M67 A;  5LHI B;  2XQ7 A;  3B57 A;  2UUA T;  2KSR A;  3KVA A;  2H3R A;  2YOE A;  4UVA B;  2LKG A;  3KDS E;  2NTX A;  5LP6 E;  5LXT E;  3PUQ A;  4X1K E;  4HN9 A;  1AJ3 A;  3ESL A;  5ABG A;  3KVB A;  4HFB A;  3JC6 D;  4P0B A;  3AB3 B;  2D2S A;  2IDO B;  3ZJ1 A;  3EAM A;  3LK2 B;  1HG2 A;  3HL6 A;  3PUS A;  4IL9 A;  2W66 A;  2X51 A;  3N9N A;  2C5J A;  4QX8 B;  2KWI B;  3IBP A;  2WZI A;  2UXD T;  3LDQ B;  3QB5 A;  3SFE A;  2BS3 A;  4UEL A;  3W15 B;  3R84 B;  1S35 A;  3R6N A;  2MYS A;  3AA0 B;  4IDO A;  2XAS B;  4AKR B;  2WZH A;  1JNZ A;  4ZOL E;  3AA1 B;  1UUS A;  3FB2 A;  4NUU A;  3F57 A;  2DI4 A;  3AE4 A;  3ZYM A;  5IUX A;  2VVN A;  3CK6 A;  4TUY E;  5L47 A;  3CIR A;  2CXD A;  4LF7 T;  2BG9 A;  1XWM A;  2XQA A;  4TV9 E;  2JRK A;  5FXW A;  3EI0 A;  2PJQ A;  5DAB A;  3ZST A;  2JQQ A;  4GYS A;  1ZV4 X;  3PE0 A;  4KX6 A;  3ZC0 A;  2MOZ A;  4JEH B;  4E7Z A;  5L3E B;  4L9I A;  5LBM A;  1JNR A;  4TNW A;  3OYZ A;  5L4E A;  5DJQ C;  5C8Y E;  1E2A A;  4U72 A;  2CA5 A;  3ZC1 A;  1SHZ C;  3UFG A;  3PUV F;  1UUR A;  2CXL A;  1BR2 A;  2ES0 A;  4F8H A;  4ILC A;  5HEJ A;  4QXC B;  3AAE B;  2R6G F;  5F8P A;  2Y8D A;  4EYU A;  1MIW A;  2LM2 A;  3NWI A;  3PTR B;  4PNI A;  4HEA A;  5IYZ E;  5LCY A;  3K3N A;  5LJM A;  2BVL A;  4BA9 A;  2N1G A;  3GA8 A;  3UTK A;  3HR0 A;  3Q5E A;  4IDZ A;  5HAX A;  3FHN A;  5LNK A;  4O2B E;  2I6H A;  1WCR A;  4LF5 T;  4TNV A;  4PW8 A;  5FXV A;  5AQF B;  4C90 A;  3ZT5 A;  4FJO A;  3UQ4 A;  1MND A;  2XM2 A;  2DL1 A;  4GOU A;  3RC3 A;  4C91 A;  4DO0 A;  4JBW F;  5KXJ A;  5J1G A;  4LMK A;  2XM1 A;  4Z90 A;  5FXX A;  4P0A A;  3UQ7 A;  2WQY A;  3AEE A;  3I0Q A;  4PK4 A;  3M65 A;  3HI2 A;  4YTN A;  3MJX A;  1Z0P A;  5JVD E;  2K3W A;  4DR4 T;  4U74 A;  5CB4 E;  2X0L B;  3VRB A;  3Q9D A;  5L3G B;  2YEV C;  4CN6 A;  5LOV E;  3RF1 A;  2ZLY A;  4HWI B;  2CBI A;  4GK0 E;  5DQW A;  3PJA A;  4Z91 A;  3BQL A;  2BS2 A;  5J2T E;  5HYA A;  4NIQ A;  2BBJ A;  3P8C D;  5J2U E;  3L8R A;  3KV5 A;  1WLX A;  3RYF E;  2VQE T;  4PFP A;  4DMV A;  4QHO A;  5JRC A;  4ZI2 C;  2WAU A;  4JI7 T;  3PU8 A;  1XMO T;  4DR2 T;  4O2A E;  2DHR A;  3ZYL A;  2CEA A;  3RYH E;  4HFV A;  1YXR A;  4TZ4 C;  2XY8 B;  2DWG A;  1D1C A;  4I50 E;  5L3D B;  1OWA A;  3GWH A;  3FZL B;  3N2G E;  3P50 A;  2LT3 A;  2W61 A;  3ZMU B;  2E9X C;  2F4V T;  3KV4 A;  3N9Q A;  1WR6 A;  5TAO A;  2LSY A;  3Q5D A;  2DWK A;  3QK6 A;  1VOM A;  3J9X 1;  3FZK B;  3CWZ B;  4AKG A;  4NXN T;  4UV8 B;  3AXJ A;  2D9D A;  4N78 D;  4B3R T;  4A97 A;  4AXP A;  1U5P A;  2SPC A;  4YSZ A;  2LE8 A;  2VL0 A;  4LFC T;  3UU4 A;  4CXY A;  3C64 A;  2QVA A;  1XNR T;  2W67 A;  2JQ9 A;  3OJA A;  3N2K E;  4I4T E;  2LRK A;  3PUW F;  3VKH A;  4QXB B;  3AED A;  2HPJ A;  3KIN B;  4DMW A;  2EHO A;  2BKP A;  2KLQ A;  4B3T T;  1WR0 A;  2C0S A;  4U33 A;  3L39 A;  2P9B A;  1M7K A;  3A8Y C;  4YY3 T;  3CQC B;  5JDG A;  2M6B A;  1OED B;  2YDS A;  4H9O C;  4UVB B;  4ZZB A;  5JDN A;  5AQL B;  1CHU A;  2NW9 A;  3N9P A;  2C5I T;  2VQF T;  4ZXL A;  2PTF A;  3G06 A;  2C5K T;  4HWH A;  5FYM A;  2YU2 A;  1ZEE A;  5ABH A;  3ZYK A;  4YSX A;  5A1L A;  3VHL A;  4CZZ B;  4DV0 T;  5AQT B;  2XQ9 A;  5LMN T;  4X64 T;  5LHH B;  4IDQ A;  2EHO C;  1B7T A;  4GKJ T;  5HXC A;  4YLH A;  1QUU A;  4NXM T;  5HEU A;  3SS1 A;  2CLY C;  5JDF A;  4HKA A;  3RYC E;  4KHZ F;  3NZP A;  2XQ3 A;  1KNZ A;  2AE9 A;  4JI5 T;  1IJ5 A;  4DBQ A;  2UXX B;  4TN7 B;  3WI3 A;  3UUN A;  5HXH A;  4IL4 A;  4UIG A;  3EVY A;  1V9D A;  3KV6 A;  3AAI A;  2NW7 A;  5EK3 A;  1Y01 A;  4AQF A;  5AQJ B;  2QRX A;  1FIO A;  4AKL A;  3UT5 E;  4HWC A;  2XTL A;  2A3D A;  2YDQ A;  5AQU B;  2X9Y A;  3E0Z A;  4ZEY A;  1YQ3 A;  4IDP A;  4HGA A;  3K1S A;  3K3Q C;  5LB7 B;  5AQQ B;  1ZHC A;  5AQK B;  2CM0 A;  1BR1 A;  2LOS A;  2EHO D;  3ZCJ A;  4H9Q C;  5HXR A;  2CE7 A;  5ETW A;  5M4Y A;  2CRB A;  5AQO B;  3AE7 A;  4JI6 T;  5L3B B;  2VUR A;  3UUB A;  1IZN B;  3RIA A;  5HCM A;  4YHJ A;  4HWF A;  3GN5 B;  4DR3 T;  3P4P A;  4OK0 A;  2LKH A;  5E0O A;  4AQF C;  3I9Y A;  4QWN B;  1I6Z A;  3SRZ A;  4AIS A;  3RRC A;  3AEA A;  3BQK A;  5JR9 C;  3AE8 A;  4DUY T;  1WRD A;  1N33 T;  3UUX B;  2W63 A;  2WU2 A;  3BQI A;  4ERR A;  2CCQ A;  4DV2 T;  3ZEF B;  4YXD A;  5JDH A;  2K9A A;  1N32 T;  2VB6 A;  2LHN A;  4CQI A;  4B6X A;  1W0B A;  2CBJ A;  2JIW A;  2JJ9 A;  4CI3 B;  4AKI A;  1VCT A;  4A98 A;  2UXN B;  5FL1 A;  1FJG T;  1WFD A;  4M1P A;  2MPK A;  3MKD A;  1KK7 A;  4QXH B;  4DR6 T;  4X65 T;  1HR0 T;  2X67 A;  4H63 H;  3U3I A;  1W9R A;  3E22 E;  1US7 B;  2HN1 A;  4JI4 T;  3RX6 A;  4YT0 A;  4HFD A;  5LG3 A;  4ADZ A;  3PUY F;  2Q9Q B;  1T72 A;  3EUH A;  3NRY A;  4PJL A;  2HH7 A;  1X79 A;  3FBZ A;  4FI5 A;  5BMV E;  3F2E A;  4HFE A;  3EDV A;  3PDY A;  2X68 A;  2OA5 A;  1HNW T;  2XQ6 A;  3CQG B;  2XSA A;  1OXZ A;  4QH4 A;  1UX4 A;  3NBX X;  4DV4 T;  1OED E;  2V7J A;  3UU3 A;  2UXB T;  4ANJ A;  4ZI7 E;  2X0H A;  5L3C B;  1XMQ T;  2NWB A;  2V7I A;  3CX8 B;  4MAL A;  1S94 A;  4IE0 A;  1N34 T;  2XAJ B;  2PBI A;  5AQS B;  2QYW A;  4G2A A;  4PJJ A;  5LGU B;  1FMV A;  2FJA A;  3N9O A;  2QA7 A;  3L09 A;  4H9S E;  3SOL A;  3IF8 B;  1MMA A;  2BG9 C;  3ONL C;  4KHP T;  3NVO A;  2I0M A;  3ZT7 A;  4JV5 T;  3JAE A;  3ZLI A;  5HWY A;  4IE7 A;  5JTG A;  3RGL A;  3ZCI A;  1D0Y A;  4KUM B;  1L0V A;  2V6Y B;  2WMN A;  1VCS A;  5KMG P;  1H7C A;  3PJA J;  5H6R B;  3TLV A;  1QLB A;  2LSJ A;  4EGW A;  3QB5 K;  2KT9 A;  1HFA A;  4DUZ T;  4AQY T;  2OV9 A;  4H63 V;  3LBX B;  2BKN A;  4U31 A;  2HPL A;  4GIW A;  1HNZ T;  4BJM A;  3ZN0 B;  3ZPO A;  3HKB E;  4LF9 T;  2B76 A;  4TV8 E;  1YKH B;  4IRE A;  3CVR A;  3ZN1 B;  5AFU L;  3PUX F;  1FEW A;  2H88 A;  4ZZC A;  3CPZ A;  5EK2 A;  5LGN B;  3U78 A;  2BKO A;  2ODU A;  2KIN B;  3VRA A;  1SA0 E;  3LJC A;  3A5X A;  3D0T A;  2UXC T;  5LGT B;  2JPF A;  2JQK A;  4DBR A;  1UX5 A;  3O4X E;  4IE4 A;  3I0O A;  3UU8 A;  2CWO A;  4LML A;  4L0R A;  4YJ3 E;  3RQU A;  4I0U A;  3RYI E;  2E5L T;  5F5W A;  2XAG B;  3TLU A;  3WAK A;  1W09 A;  5LHG B;  3ZMS B;  3Q5X A;  2L8K A;  3FZH B;  2ZM8 A;  2FUP A;  1IBK T;  2K5B B;  1J5E T;  4CN4 A;  3UU6 A;  5IHY A;  3FZF B;  4EEB A;  1UGO A;  4KP3 C;  1FMW A;  5F3J A;  4DID B;  4UF0 A;  4U2Z A;  3I1A A;  2G0U A;  4BAY B;  4WYV A;  2IUB A;  3FXE B;  5L4H A;  2ACX A;  2V5D A;  3DP7 A;  3T1H T;  2GK9 A;  4GK5 E;  5LG4 A;  2MBG A;  3ZKR A;  5FL0 A;  1YKE B;  3P4R A;  3HKC E;  4DR1 T;  3ABV A;  2E9X B;  2VWA A;  4EED A;  2BVM A;  4JEU B;  4UEM A;  2CMR A;  2CXF A;  4KI0 F;  2RP4 A;  1CUN A;  3RI5 A;  3BK9 A;  4JUY A;  3E08 A;  3EAB A;  5JRE A;  2JMH A;  4DVD A;  3MK7 C;  3AA7 B;  4TWF A;  4AKH A;  2IW5 B;  1KF6 A;  4AIU A;  1LKX A;  3B5M A;  5LYJ E;  4B3S T;  4JI8 T;  5AQI B;  3C50 A;  3AAA B;  3O1I A;  3TLW A;  3LK3 B;  4PJM A;  3F31 A;  5CA1 E;  1LVK A;  5H6Q B;  2UU9 T;  4U7I A;  3ANW A;  3IEE A;  3J7Y q;  3QNU A;  2LM9 A;  2N2N A;  4CXW A;  4XZC A;  2J1D G;  4CXX A;  3JAD A;  2VL8 A;  4MFR A;  4ILA A;  3ZT6 A;  2E2A A;  1LVF A;  4JI2 T;  3PUA A;  1E7P A;  2XQ4 A;  3AXJ B;  5JDM A;  4HE8 A;  3MXZ A;  2LHR A;  3RRW A;  1O3X A;  1DU2 A;  2ACZ A;  4MHC A;  2YKS A;  3MAC A;  5AQV B;  1G73 A;  3ETU A;  1HF8 A;  3NKZ A;  2PFV A;  2V7M A;  2W62 A;  1NAF A;  2A72 A;  4GYR A;  4HWD A;  3RIU A;  2ZM2 A;  2XJ7 A;  2YN6 A;  3CKD A;  2H7V C;  4KBM B;  2Y48 B;  3HKD E;  4BJN A;  3I9W A;  2E5V A;  4OFZ A;  4O4L E;  3UUL A;  3PUR A;  4B3M T;  5FY1 A;  1D1A A;  1N36 T;  2LRL A;  2VKJ A;  4JI3 T;  4LF6 T;  5IWA T;  2VKO A;  3HA4 A;  3ZSS A;  1NWM X;  2QGS A;  4I43 B;  2H7O A;  5JH7 E;  2NW8 A;  3JAF A;  3X1D A;  1SUM B;  3AVS A;  2XZE A;  3C4X A;  4K0K T;  5EK4 A;  3FBL A;  3Q2M A;  2DNX A;  2LSG A;  4NUV A;  2XQ5 A;  5FXZ A;  5ABF B;  3AE5 A;  1Y64 B;  4IGU A;  4OYK A;  1IBM T;  3RIU C;  2VVS A;  1BR4 A;  2XPK A;  4DR5 T;  4CN1 A;  2WWU A;  3P4W A;  4WZX A;  5FVK A;  2WDQ A;  1ZKE A;  3AE2 A;  4JI0 T;  4AQG A;  3ZJ2 A;  1KFY A;  4UR9 A;  2Z6E A;  4IE6 A;  3K3O A;  1M62 A;  5HEO A;  4Z8X A;  1HCI A;  3ZMV B;  1IBL T;  1NEN A;  4LMJ A;  2CPT A;  3OVU A;  4PJN A;  2DLR A;  4ZS3 A;  4E7S A;  1KNR A;  1UK5 A;  2ODV A;  3RC8 A;  2PG8 A;  5JR9 B;  1YD8 G;  4YJ2 E;  4G63 A;  5FNV E;  4QKN A;  1W0A A;  2FBW A;  2LLY A;  4OYJ A;  4P1N A;  1X9B A;  2MTQ A;  3N5L A;  2LJL A;  3TLS A;  3MZK B;  4U2Y A;  1D1B A;  5FMN A;  4UXN B;  3UU5 A;  2Q9Q A;  2W00 A;  2VK9 A;  2V6X A;  3AE1 A;  2IHR 1;  4JI1 T;  3K8P C;  1G8X A;  4O8S A;  3H3M A;  5HXE A;  4YSY A;  3CML A;  2XSB A;  5CJ5 A;  3KV9 A;  2J4G A;  2XAQ B;  3SFD A;  2W0G A;  4COF A;  3A7M A;  3AE3 A;  4U7Y A;  5HWX A;  4EZH A;  2OLT A;  1R8I A;  5ADX L;  4CI2 B;  3O1H A;  4TWD A;  5HXS A;  4QH5 A;  2NP9 A;  4Q25 A;  2VKD A;  4O4H E;  2YDR A;  5AQG B;  2I59 A;  4QX7 B;  2CWY A;  3FZM B;  3H3A A;  4UVC B;  5BR8 T;  3N9L A;  2IC9 A;  2Q9Q C;  3HKE E;  1XDO A;  4EYY R;  2ZM0 A;  4XBF B;  2VAS A;  2JMK A;  4I55 E;  4U3C A;  3EDU A;  2UUC T;  1HX8 A;  4YFS A;  1T7S A;  4WNK A;  1MIV A;  2HN2 A;  3AEG A;  4OHF A;  4L5G A;  3DTO A;  2BDE A;  2V6Y A;  4WBO A;  2B1E A;  3QOF A;  2BG9 B;  3N2O A;  1J1J A;  2KND A;  3RKO A;  3O9X A;  3OYX A;  4DND A;  2YIN A;  4EV6 A;  3VU7 H;  4X1I E;  5CA0 E;  3LBX A;  2D0T A;  2K24 A;  2FJD A;  2V7L A;  1KNP A;  5HEH A;  2WSS V;  2IIU A;  3AEC A;  3RKG A;  1MMD A;  3TLT A;  3KBU A;  3P4Q A;  4X62 T;  4LF4 T;  4DV6 T;  2RA1 A;  4WW0 A;  2Q9Q D;  4TX5 A;  3KFW X;  5HCJ A;  3PUZ F;  4HTE A;  4YTP A;  3QUJ A;  2AXD S;  2V8S V;  4EOZ B;  4HFC A;  2HHH T;  3C98 B;  3GMI A;  2IC6 A;  2XUE A;  1ZP0 A;  2NTY A;  5FP3 A;  3H37 A;  2X9W A;  2A2F X;  4IST A;  4JLE A;  2V1D B;  2D5U A;  2V7K A;  3N9M A;  3QC9 A;  2YK0 A;  3RPU A;  5J0Z A;  4IDN A;  3ONX A;  4O4I E;  4A56 A;  2H89 A;  2CHO A;  4IHJ E;  1GQE A;  1XZY A;  1UCU A;  2LSI A;  2X9H A;  4DV7 T;  1SE7 A;  2XQY A;  3V5U A;  4PK5 A;  5FY0 A;  3PV0 F;  5FKY A;  1ZOY A;  3CX7 B;  3Q5W A;  3T1Y T;  2CHN A;  4A5X A;  2KZ7 B;  4PFO A;  1LRZ A;  4LFA T;  3C4Z A;  3O1J A;  1HG5 A;  3AE9 A;  3V5S A;  2BZB A;  3PUG A;  2WM9 A;  2E9X A;  2JQH A;  3UUM A;  4AI6 A;  1QSD A;  2W4X A;  1KEY A;  3ZMZ B;  5AQN B;  2FJE A;  3OPC A;  3L3P A;  1T98 A;  4GKK T;  2V26 A;  3ETV A;  5JDL A;  5LMU T;  4ZS2 A;  2WU5 A;  3OKQ A;  3UFE A;  5LJN A;  3NZQ A;  2LEH A;  3M3Z B;  2V5C A;  4ISS A;  4CI1 B;  1XNQ T;  4H9N C;  2XAF B;  4IIJ E;  2WCA A;  5EZY E;  1WYB A;  2J47 A;  2XQ8 A;  2X66 A;  4K0U A;  3AE6 A;  2E8I A;  5JRC B;  1NEK A;  4TWH A;  2IAK A;  5KDM C;  1HTJ F;  4EZ4 A;  4UF0 B;  1U4Q A;  1HNX T;  2XAH B;  4H9P C;  2ZMA A;  2NOX A;  1VRB A;  4DV5 T;  3LK4 2;  4H9R C;  4HFI A;  4ZI3 C;  4OX9 T;  4P09 A;  5CGM A;  1BR0 A;  4EB6 E;  2WY2 A;  5KX5 E;  5JDQ A;  1HS7 A;  4ZHQ E;  1EZ3 A;  3C4W A;  3DJB A;  4LFB T;  4X66 T;  5DQV A;  4MBQ A;  2X9X A;  5L3F B;  2K48 A;  4WBN E;  4IE5 A;  2MAW A;  2L3L A;  1T8B A;  4O4J E;  1OED A;  2WWV A;  2WDR A;  3VR8 A;  4ZI2 D;  3S4U A;  4ILU A;  2WB5 A;  2W2U A;  2N9D A;  2LSK A;  1J5W A;  2WS3 A;  4QH1 A;  2LOP A;  2ZM6 T;  2BG9 E;  4NPP A;  4PK6 A;  2L9Q A;  3ZMT B;  3ONJ A;  1YW0 A;  4YTM A;  2KWH A;  5FVL A;  5FY7 A;  2E9X D;  3C51 A;  2Y6X A;  5L2L A;  4IT4 A;  4PAG A;  3RHW A;  3P4S A;  3AA6 B;  4DV3 T;  4ZI3 D;  4YHH T;  1OED C;  1WYC A;  2IML A;  5LA6 E;  2D0U A;  4XAX B;  1MIY A;  3OBV E;  4EAH A;  3ANW B;  5GON E;  2EHO B;  3TKL B;  3MA9 A;  3NRX A; 
#chains in the Genus database with same CATH homology
 3FZH B;  5AQU B;  5AQF B;  5AQP B;  5AQR B;  1M62 A;  2D9D A;  5AQV B;  4HWF A;  3FZF B;  3FZL B;  5AQG B;  5AQT B;  4HWI B;  1UGO A;  5AQO B;  1HX1 B;  3FZM B;  5AQL B;  3FZK B;  5AQH B;  5AQJ B;  3LDQ B;  5AQM B;  5AQQ B;  5AQI B;  5AQK B;  1T7S A;  3M3Z B;  1I6Z A;  4HWC A;  5AQS B;  5AQN B;  4HWD A;  4HWH A;  1UK5 A;  1M7K A;  3A8Y C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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